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Conserved domains on  [gi|392920044|ref|NP_001256134|]
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EGF-like domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 184-231 7.75e-09

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 51.58  E-value: 7.75e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  184 GTMYDEVDEKCVPCPRGEFQDEHGRTTCKTCPDSTTTVGTGTQKKEQC 231
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 238-285 8.76e-06

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 42.72  E-value: 8.76e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  238 GYFYDTSSKMCETCGLRGYQPKSGQDRCIPCPDGTVPIYQNSTTIGHC 285
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
EGF_3 super family cl48154
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 399-439 3.84e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


The actual alignment was detected with superfamily member pfam12947:

Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 3.84e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 392920044  399 CKASTHNCHWLAACidlpdENHKKMYSCKCKPGFVGNGFHC 439
Cdd:pfam12947   1 CSDNNGGCHPNATC-----TNTGGSFTCTCNDGYTGDGVTC 36
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 300-338 1.40e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 1.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 392920044  300 STCEPCPIGSFKSADDMV-CMMCPTGRTTLSKASKALSAC 338
Cdd:pfam07699   9 EPCIPCPRGTYQPEEGQLsCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like super family cl06646
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 346-393 1.79e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


The actual alignment was detected with superfamily member pfam07699:

Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 1.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  346 GTILDHSTFKCEPCDFGTYMDEYDGRICKTCPVSTTTYQQGANTAKMC 393
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 184-231 7.75e-09

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 51.58  E-value: 7.75e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  184 GTMYDEVDEKCVPCPRGEFQDEHGRTTCKTCPDSTTTVGTGTQKKEQC 231
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 238-285 8.76e-06

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 42.72  E-value: 8.76e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  238 GYFYDTSSKMCETCGLRGYQPKSGQDRCIPCPDGTVPIYQNSTTIGHC 285
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 399-439 3.84e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 3.84e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 392920044  399 CKASTHNCHWLAACidlpdENHKKMYSCKCKPGFVGNGFHC 439
Cdd:pfam12947   1 CSDNNGGCHPNATC-----TNTGGSFTCTCNDGYTGDGVTC 36
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 300-338 1.40e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 1.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 392920044  300 STCEPCPIGSFKSADDMV-CMMCPTGRTTLSKASKALSAC 338
Cdd:pfam07699   9 EPCIPCPRGTYQPEEGQLsCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 346-393 1.79e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 1.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  346 GTILDHSTFKCEPCDFGTYMDEYDGRICKTCPVSTTTYQQGANTAKMC 393
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
 
Name Accession Description Interval E-value
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 184-231 7.75e-09

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 51.58  E-value: 7.75e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  184 GTMYDEVDEKCVPCPRGEFQDEHGRTTCKTCPDSTTTVGTGTQKKEQC 231
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 238-285 8.76e-06

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 42.72  E-value: 8.76e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  238 GYFYDTSSKMCETCGLRGYQPKSGQDRCIPCPDGTVPIYQNSTTIGHC 285
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
EGF_3 pfam12947
EGF domain; This family includes a variety of EGF-like domain homologs. This family includes ...
 399-439 3.84e-04

EGF domain; This family includes a variety of EGF-like domain homologs. This family includes the C-terminal domain of the malaria parasite MSP1 protein.


Pssm-ID: 463759 [Multi-domain]  Cd Length: 36  Bit Score: 37.96  E-value: 3.84e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 392920044  399 CKASTHNCHWLAACidlpdENHKKMYSCKCKPGFVGNGFHC 439
Cdd:pfam12947   1 CSDNNGGCHPNATC-----TNTGGSFTCTCNDGYTGDGVTC 36
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 300-338 1.40e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.56  E-value: 1.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 392920044  300 STCEPCPIGSFKSADDMV-CMMCPTGRTTLSKASKALSAC 338
Cdd:pfam07699   9 EPCIPCPRGTYQPEEGQLsCLACPLGTTTDSPGATSISDC 48
Ephrin_rec_like pfam07699
Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region ...
 346-393 1.79e-03

Tyrosine-protein kinase ephrin type A/B receptor-like; This family has repeats of a region rich in cysteines. It is found in various ephrin type A and B receptors, which have tyrosine kinase activity.


Pssm-ID: 429604 [Multi-domain]  Cd Length: 48  Bit Score: 36.17  E-value: 1.79e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 392920044  346 GTILDHSTFKCEPCDFGTYMDEYDGRICKTCPVSTTTYQQGANTAKMC 393
Cdd:pfam07699   1 GTYSNTGLEPCIPCPRGTYQPEEGQLSCLACPLGTTTDSPGATSISDC 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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