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Conserved domains on  [gi|392921408|ref|NP_001256481|]
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Serpentine Receptor, class T [Caenorhabditis elegans]

Protein Classification

class I serpentine receptor( domain architecture ID 10563430)

class I serpentine receptor (Sri) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Gene Ontology:  GO:0016020
TCDB:  9.A.14

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
3-305 4.52e-108

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 313539  Cd Length: 303  Bit Score: 317.56  E-value: 4.52e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408    3 APCPETLPNGYLLTLSIIGGISIPMNLLALYMIWFQSPGMHGYKYCLTYMQVASFIVEINVTWLVPAYHFFPLTGGIAAG 82
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408   83 EIIRKF-VSNHTGVTIWIFLFCFLLPASLLCLFYRHNAASKINQSGSNNLYLEKLVMILTHIFPFLTAFGTWNCQMTFAQ 161
Cdd:pfam10327  81 FLATVFgISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408  162 KYEYLSQNYPECLFWLAS-DRFEAYDYkmNPWIVSTAAAAITFLVITASYGGYHGIHTMIILQRLRAHMSVQTYQMHITA 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSlPNFAIYDY--NPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAA 238
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 392921408  241 LISLALQMLTPSVFAVPVYVWVTVVLTNAIDLQGIVSWSPCLMSTHSILMSSVMIVTNATYRRVL 305
Cdd:pfam10327 239 LRSLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
 
Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
3-305 4.52e-108

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 317.56  E-value: 4.52e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408    3 APCPETLPNGYLLTLSIIGGISIPMNLLALYMIWFQSPGMHGYKYCLTYMQVASFIVEINVTWLVPAYHFFPLTGGIAAG 82
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408   83 EIIRKF-VSNHTGVTIWIFLFCFLLPASLLCLFYRHNAASKINQSGSNNLYLEKLVMILTHIFPFLTAFGTWNCQMTFAQ 161
Cdd:pfam10327  81 FLATVFgISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408  162 KYEYLSQNYPECLFWLAS-DRFEAYDYkmNPWIVSTAAAAITFLVITASYGGYHGIHTMIILQRLRAHMSVQTYQMHITA 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSlPNFAIYDY--NPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAA 238
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 392921408  241 LISLALQMLTPSVFAVPVYVWVTVVLTNAIDLQGIVSWSPCLMSTHSILMSSVMIVTNATYRRVL 305
Cdd:pfam10327 239 LRSLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
 
Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
3-305 4.52e-108

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 317.56  E-value: 4.52e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408    3 APCPETLPNGYLLTLSIIGGISIPMNLLALYMIWFQSPGMHGYKYCLTYMQVASFIVEINVTWLVPAYHFFPLTGGIAAG 82
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408   83 EIIRKF-VSNHTGVTIWIFLFCFLLPASLLCLFYRHNAASKINQSGSNNLYLEKLVMILTHIFPFLTAFGTWNCQMTFAQ 161
Cdd:pfam10327  81 FLATVFgISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408  162 KYEYLSQNYPECLFWLAS-DRFEAYDYkmNPWIVSTAAAAITFLVITASYGGYHGIHTMIILQRLRAHMSVQTYQMHITA 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSlPNFAIYDY--NPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAA 238
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 392921408  241 LISLALQMLTPSVFAVPVYVWVTVVLTNAIDLQGIVSWSPCLMSTHSILMSSVMIVTNATYRRVL 305
Cdd:pfam10327 239 LRSLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
10-311 9.28e-20

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 87.98  E-value: 9.28e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408   10 PNGYLLTLSIIGGISIPMNLLALYMIWFQSPG-MHGYKYCLTYMQVASFIVEINVTWLVPAYHFFPLTGGIAAGeiIRKF 88
Cdd:pfam10318   3 PDFLSTSLHIITVISIPIHIFGFYCILFKTPKkMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLG--LLSY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408   89 VSNHTGVTIWIFLFCF-LLPASLLCLF-YRHNAASKiNQSGSNNLYLEKLVMILTHIFPFLTAFGTWNcqMTFAQKY--E 164
Cdd:pfam10318  81 LGVPTPIQFYIGVTSLaLVGVSIILLFeNRYSILFT-NKKRITWKKTRVLYLIFNYIIALLFLIPIYL--NIPDQEAakL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392921408  165 YLSQNYPeCLFWLASDRFEAYDYKMNPWIVSTAAAAITFLVITASygGYHGIHT-MIILQRLRAHMSVQTYQMHITALIS 243
Cdd:pfam10318 158 KVLKKLP-CLPPEFFDNPPVFVLAIDSTYFLICIVLLILILIIQI--LFFVFLTiYYLFKSVKSSLSKKTRKLQKKFFIA 234
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 392921408  244 LALQMLTPSVFAVPVYVWVTVVLTNAIDLQGIVSWSPCLMSTHSILMSSVMIVTNATYRRVLKEKISK 311
Cdd:pfam10318 235 LIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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