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Conserved domains on  [gi|392922548|ref|NP_001256741|]
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F-box domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 783-913 4.24e-20

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


:

Pssm-ID: 396410  Cd Length: 141  Bit Score: 87.63  E-value: 4.24e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  783 LKEILKAhETPLKVKCIVMLGVDLPIIRRILSYLDKNELKMIFLNYdaysrvEEEELDTTKLVELDQWKMAEELRV-LDC 861
Cdd:pfam01827   7 FLNILKS-KKCLHVKEISLSGLSFSEVASILPYFDAGTLEEIELSS------ESDEDQFEEIVELEQWKNAKSLKIeGSS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 392922548  862 GLSFSVENIGHFLKVEVTLRTISVEDLVYLKEIFKTSSANRNFNIKSRSFDA 913
Cdd:pfam01827  80 LSSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNP 131
FTH super family cl28746
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 428-553 4.60e-16

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


The actual alignment was detected with superfamily member pfam01827:

Pssm-ID: 396410  Cd Length: 141  Bit Score: 76.07  E-value: 4.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  428 KTLLDTVETMLRErSSKLKVNTfvVTLSEKPINEhLPGIMACLEPRVLKEIILTGDKGELHCDGLVNLEQWKNASLLSIN 507
Cdd:pfam01827   1 EKIIESFLNILKS-KKCLHVKE--ISLSGLSFSE-VASILPYFDAGTLEEIELSSESDEDQFEEIVELEQWKNAKSLKIE 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 392922548  508 NFYVKAA-ISNFLHFQEVRVTFAKLTYDDLIMLKEHFLvneKPSTFE 553
Cdd:pfam01827  77 GSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILL---KSSTFQ 120
FBOX smart00256
A Receptor for Ubiquitination Targets;
655-679 9.76e-03

A Receptor for Ubiquitination Targets;


:

Pssm-ID: 197608  Cd Length: 41  Bit Score: 34.72  E-value: 9.76e-03
                           10        20
                   ....*....|....*....|....*
gi 392922548   655 IIEKCSFVTILSLRKVCKNLRNFID 679
Cdd:smart00256   9 ILSKLDPKDLLRLRKVSRKWRSLID 33
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 783-913 4.24e-20

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 87.63  E-value: 4.24e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  783 LKEILKAhETPLKVKCIVMLGVDLPIIRRILSYLDKNELKMIFLNYdaysrvEEEELDTTKLVELDQWKMAEELRV-LDC 861
Cdd:pfam01827   7 FLNILKS-KKCLHVKEISLSGLSFSEVASILPYFDAGTLEEIELSS------ESDEDQFEEIVELEQWKNAKSLKIeGSS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 392922548  862 GLSFSVENIGHFLKVEVTLRTISVEDLVYLKEIFKTSSANRNFNIKSRSFDA 913
Cdd:pfam01827  80 LSSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNP 131
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 428-553 4.60e-16

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 76.07  E-value: 4.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  428 KTLLDTVETMLRErSSKLKVNTfvVTLSEKPINEhLPGIMACLEPRVLKEIILTGDKGELHCDGLVNLEQWKNASLLSIN 507
Cdd:pfam01827   1 EKIIESFLNILKS-KKCLHVKE--ISLSGLSFSE-VASILPYFDAGTLEEIELSSESDEDQFEEIVELEQWKNAKSLKIE 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 392922548  508 NFYVKAA-ISNFLHFQEVRVTFAKLTYDDLIMLKEHFLvneKPSTFE 553
Cdd:pfam01827  77 GSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILL---KSSTFQ 120
FBOX smart00256
A Receptor for Ubiquitination Targets;
655-679 9.76e-03

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 34.72  E-value: 9.76e-03
                           10        20
                   ....*....|....*....|....*
gi 392922548   655 IIEKCSFVTILSLRKVCKNLRNFID 679
Cdd:smart00256   9 ILSKLDPKDLLRLRKVSRKWRSLID 33
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 783-913 4.24e-20

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 87.63  E-value: 4.24e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  783 LKEILKAhETPLKVKCIVMLGVDLPIIRRILSYLDKNELKMIFLNYdaysrvEEEELDTTKLVELDQWKMAEELRV-LDC 861
Cdd:pfam01827   7 FLNILKS-KKCLHVKEISLSGLSFSEVASILPYFDAGTLEEIELSS------ESDEDQFEEIVELEQWKNAKSLKIeGSS 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 392922548  862 GLSFSVENIGHFLKVEVTLRTISVEDLVYLKEIFKTSSANRNFNIKSRSFDA 913
Cdd:pfam01827  80 LSSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNP 131
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
 428-553 4.60e-16

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 76.07  E-value: 4.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392922548  428 KTLLDTVETMLRErSSKLKVNTfvVTLSEKPINEhLPGIMACLEPRVLKEIILTGDKGELHCDGLVNLEQWKNASLLSIN 507
Cdd:pfam01827   1 EKIIESFLNILKS-KKCLHVKE--ISLSGLSFSE-VASILPYFDAGTLEEIELSSESDEDQFEEIVELEQWKNAKSLKIE 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 392922548  508 NFYVKAA-ISNFLHFQEVRVTFAKLTYDDLIMLKEHFLvneKPSTFE 553
Cdd:pfam01827  77 GSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILL---KSSTFQ 120
FBOX smart00256
A Receptor for Ubiquitination Targets;
655-679 9.76e-03

A Receptor for Ubiquitination Targets;


Pssm-ID: 197608  Cd Length: 41  Bit Score: 34.72  E-value: 9.76e-03
                           10        20
                   ....*....|....*....|....*
gi 392922548   655 IIEKCSFVTILSLRKVCKNLRNFID 679
Cdd:smart00256   9 ILSKLDPKDLLRLRKVSRKWRSLID 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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