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Conserved domains on  [gi|922581565|ref|NP_001257074|]
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Calponin-homology (CH) domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2610-2704 1.17e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 1.17e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2610 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2689
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   2690 EHVPGSPFLVMIVDT 2704
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2516-2607 8.89e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 8.89e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2516 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2594
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581565   2595 VKGSPFVVHVSLP 2607
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2421-2510 1.44e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.44e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2421 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2499
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581565   2500 VKGSPFAVSAD 2510
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1332-1415 6.96e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 6.96e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1332 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1406
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581565   1407 VPGSPFLCQ 1415
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2012-2101 1.04e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 1.04e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2012 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2091
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
                            90
                    ....*....|
gi 922581565   2092 SPFKTEVIDP 2101
Cdd:smart00557   84 SPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1086-1179 1.53e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.53e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1086 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1164
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   1165 EVLKNSPFEVNIVDA 1179
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
216-300 9.27e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 9.27e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    216 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 292
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581565    293 PIKVEILP 300
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1243-1332 5.78e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.03  E-value: 5.78e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1243 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1318
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581565   1319 PVTGSPFTCRAYDP 1332
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1522-1601 1.72e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.72e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1522 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1600
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581565   1601 A 1601
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
124-209 1.80e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.80e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    124 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 203
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581565    204 GSPLSV 209
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1839-1920 8.32e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 8.32e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1839 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 1918
Cdd:smart00557   12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91

                    ..
gi 922581565   1919 DP 1920
Cdd:smart00557   92 PA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2197-2284 1.34e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.18  E-value: 1.34e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2197 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2275
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581565   2276 PFTVNVVDP 2284
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1920-2008 2.76e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 73.41  E-value: 2.76e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1920 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 1996
Cdd:smart00557    1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 922581565   1997 LSDGPYEVFISH 2008
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1429-1512 1.22e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.22e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1429 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1507
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581565   1508 KAYDA 1512
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
31-109 2.35e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 2.35e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565     31 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 107
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581565    108 ED 109
Cdd:smart00557   91 GP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2118-2191 3.46e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 3.46e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581565   2118 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2191
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2303-2379 3.26e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 3.26e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581565   2303 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2379
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
IG_FLMN super family cl42963
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1754-1817 4.62e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


The actual alignment was detected with superfamily member smart00557:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 49.91  E-value: 4.62e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565   1754 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1817
Cdd:smart00557   16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
PTZ00121 super family cl31754
MAEBL; Provisional
671-1093 1.91e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  671 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 750
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  751 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 827
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  828 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV-------KS 900
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakKA 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  901 EDDKILAKHgfTRKPEpsiEIQEPVTEQIRDDVVETAIAPEV------------PLRPVEELPHSPAPSSRSTPATTPKL 968
Cdd:PTZ00121 1671 EEDKKKAEE--AKKAE---EDEKKAAEALKKEAEEAKKAEELkkkeaeekkkaeELKKAEEENKIKAEEAKKEAEEDKKK 1745
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  969 SAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKSS 1048
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDIF 1804
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 922581565 1049 SKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1093
Cdd:PTZ00121 1805 DNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
Filamin super family cl44411
Filamin/ABP280 repeat;
1666-1730 7.69e-04

Filamin/ABP280 repeat;


The actual alignment was detected with superfamily member pfam00630:

Pssm-ID: 395505  Cd Length: 89  Bit Score: 40.74  E-value: 7.69e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565  1666 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1730
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2610-2704 1.17e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 1.17e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2610 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2689
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   2690 EHVPGSPFLVMIVDT 2704
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2607-2697 1.34e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.34e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2607 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2686
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581565  2687 WHGEHVPGSPF 2697
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2516-2607 8.89e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 8.89e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2516 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2594
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581565   2595 VKGSPFVVHVSLP 2607
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2421-2510 1.44e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.44e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2421 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2499
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581565   2500 VKGSPFAVSAD 2510
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1332-1415 6.96e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 6.96e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1332 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1406
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581565   1407 VPGSPFLCQ 1415
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2012-2101 1.04e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 1.04e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2012 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2091
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
                            90
                    ....*....|
gi 922581565   2092 SPFKTEVIDP 2101
Cdd:smart00557   84 SPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1086-1179 1.53e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.53e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1086 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1164
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   1165 EVLKNSPFEVNIVDA 1179
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2012-2095 1.95e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 82.34  E-value: 1.95e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2012 VRASGDALRKAQRARTARFEVINVEQNrGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2091
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ....
gi 922581565  2092 SPFK 2095
Cdd:pfam00630   86 SPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
216-300 9.27e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 9.27e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    216 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 292
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581565    293 PIKVEILP 300
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1243-1332 5.78e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.03  E-value: 5.78e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1243 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1318
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581565   1319 PVTGSPFTCRAYDP 1332
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1522-1601 1.72e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.72e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1522 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1600
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581565   1601 A 1601
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
124-209 1.80e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.80e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    124 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 203
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581565    204 GSPLSV 209
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1839-1920 8.32e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 8.32e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1839 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 1918
Cdd:smart00557   12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91

                    ..
gi 922581565   1919 DP 1920
Cdd:smart00557   92 PA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2197-2284 1.34e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.18  E-value: 1.34e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2197 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2275
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581565   2276 PFTVNVVDP 2284
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1920-2008 2.76e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 73.41  E-value: 2.76e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1920 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 1996
Cdd:smart00557    1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 922581565   1997 LSDGPYEVFISH 2008
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1429-1512 1.22e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.22e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1429 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1507
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581565   1508 KAYDA 1512
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
31-109 2.35e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 2.35e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565     31 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 107
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581565    108 ED 109
Cdd:smart00557   91 GP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2197-2278 5.23e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 5.23e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2197 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 2276
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581565  2277 FT 2278
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1509-1593 1.14e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 1.14e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1509 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1586
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581565  1587 ISVPGSP 1593
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2421-2505 1.53e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.53e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2421 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2499
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581565  2500 VKGSPF 2505
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1329-1412 2.82e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.82e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1329 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1403
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581565  1404 NEPVPGSPF 1412
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
216-295 2.79e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 64.62  E-value: 2.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   216 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 293
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581565   294 IK 295
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1917-2003 4.68e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 64.23  E-value: 4.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1917 VLDPSAVRV--IGLKNAPVGVEQQFSVDYTNSGASiASVEVRHGD-QTIPITVKKMKPGQLLCTFTPFVDGPHQVEVIID 1993
Cdd:pfam00630    1 AADASKVKAsgPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 922581565  1994 GVPLSDGPYE 2003
Cdd:pfam00630   80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
125-206 8.81e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 8.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   125 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 204
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581565   205 SP 206
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1083-1173 1.76e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.31  E-value: 1.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1083 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1161
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581565  1162 FNKEVLKNSPFE 1173
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1256-1326 1.13e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.00  E-value: 1.13e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1256 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1326
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1429-1506 2.47e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 2.47e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581565  1429 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1506
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2118-2191 3.46e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 3.46e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581565   2118 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2191
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2526-2601 4.66e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 4.66e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581565  2526 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2601
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
2098-2184 9.41e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 9.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2098 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 2176
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581565  2177 GFQIPGYP 2184
Cdd:pfam00630   80 GQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
31-104 2.31e-09

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 56.53  E-value: 2.31e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565    31 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 104
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2303-2379 3.26e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 3.26e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581565   2303 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2379
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
2281-2371 2.43e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.45  E-value: 2.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2281 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2360
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581565  2361 SIYLYWNELPV 2371
Cdd:pfam00630   73 TVSVKFNGQHI 83
Filamin pfam00630
Filamin/ABP280 repeat;
1842-1913 1.25e-07

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 51.52  E-value: 1.25e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1842 IVGEQTELKILIdSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPF 1913
Cdd:pfam00630   18 VVGKPAEFTVDT-RDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1754-1817 4.62e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 49.91  E-value: 4.62e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565   1754 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1817
Cdd:smart00557   16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
Filamin pfam00630
Filamin/ABP280 repeat;
1754-1818 1.70e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 48.44  E-value: 1.70e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565  1754 AGQKYSFDVNSDD-KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPIG 1818
Cdd:pfam00630   19 VGKPAEFTVDTRDaGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIP 84
PTZ00121 PTZ00121
MAEBL; Provisional
671-1093 1.91e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  671 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 750
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  751 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 827
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  828 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV-------KS 900
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakKA 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  901 EDDKILAKHgfTRKPEpsiEIQEPVTEQIRDDVVETAIAPEV------------PLRPVEELPHSPAPSSRSTPATTPKL 968
Cdd:PTZ00121 1671 EEDKKKAEE--AKKAE---EDEKKAAEALKKEAEEAKKAEELkkkeaeekkkaeELKKAEEENKIKAEEAKKEAEEDKKK 1745
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  969 SAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKSS 1048
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDIF 1804
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 922581565 1049 SKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1093
Cdd:PTZ00121 1805 DNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
999-1086 5.10e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 5.10e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    999 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1077
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581565   1078 PFAVRVYDA 1086
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1029-1079 6.14e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 6.14e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1029 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1079
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1666-1730 7.69e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 40.74  E-value: 7.69e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565  1666 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1730
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1666-1733 8.33e-03

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 37.97  E-value: 8.33e-03
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922581565   1666 LNSAQIGQKKGFTIDNINK-SSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEI-YLDHEI 1733
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYtVSYTPTEPGDYTVTVkFGGEHI 81
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2610-2704 1.17e-28

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.54  E-value: 1.17e-28
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2610 PSKVRVYGPGVEHGILSLfKSNFVVETRGAGAGQLTVRVRGPKGAfNVEMQREKKNERTIHCKYEPKEPGDYQVEVKWHG 2689
Cdd:smart00557    1 ASKVKASGPGLEKGVVGE-PAEFTVDTRDAGGGELEVEVTGPSGK-KVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   2690 EHVPGSPFLVMIVDT 2704
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2607-2697 1.34e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 94.28  E-value: 1.34e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2607 PPDPSKVRVYGPGVEHGILSLfKSNFVVETRGAGaGQLTVRVRGPKGAFnVEMQREKKNERTIHCKYEPKEPGDYQVEVK 2686
Cdd:pfam00630    1 AADASKVKASGPGLEPGVVGK-PAEFTVDTRDAG-GEGEVEVTGPDGSP-VPVEVTDNGDGTYTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|.
gi 922581565  2687 WHGEHVPGSPF 2697
Cdd:pfam00630   78 FNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2516-2607 8.89e-22

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 91.90  E-value: 8.89e-22
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2516 ADLIDVDASTLKIGIINENIKTLIDTRRAGSGQLSALCMGP-NKPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEH 2594
Cdd:smart00557    1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPsGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|...
gi 922581565   2595 VKGSPFVVHVSLP 2607
Cdd:smart00557   81 IPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2421-2510 1.44e-20

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 88.43  E-value: 1.44e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2421 SRIMVRGDGLHRAVLKEHNEFIIDGSDINkEGRITATLLG-SKADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2499
Cdd:smart00557    2 SKVKASGPGLEKGVVGEPAEFTVDTRDAG-GGELEVEVTGpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|.
gi 922581565   2500 VKGSPFAVSAD 2510
Cdd:smart00557   81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1332-1415 6.96e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.81  E-value: 6.96e-19
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1332 PAKIKVGA--IPKGLLDKPVYFTVDASEAGVGNLEVAVCEGR---VPSMAHALGHHKYDISFVPKEDVDHTITVRFNNEP 1406
Cdd:smart00557    1 ASKVKASGpgLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                    ....*....
gi 922581565   1407 VPGSPFLCQ 1415
Cdd:smart00557   81 IPGSPFTVK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2012-2101 1.04e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 83.04  E-value: 1.04e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2012 VRASGDALRKAQRARTARFEVINVEQNRGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2091
Cdd:smart00557    4 VKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPG 83
                            90
                    ....*....|
gi 922581565   2092 SPFKTEVIDP 2101
Cdd:smart00557   84 SPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1086-1179 1.53e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 1.53e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1086 ASEIIV-GEIPNQSNLNDTVEFTVDAGRAGFGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNITFNK 1164
Cdd:smart00557    1 ASKVKAsGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGT--YTVSYTPTEPGDYTVTVKFGG 78
                            90
                    ....*....|....*
gi 922581565   1165 EVLKNSPFEVNIVDA 1179
Cdd:smart00557   79 EHIPGSPFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
2012-2095 1.95e-18

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 82.34  E-value: 1.95e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2012 VRASGDALRKAQRARTARFEVINVEQNrGELDVMVSDPKGGPLPVRCYKQQDDSYWVEFTPEHLGTHTIEVTFGDVPVPG 2091
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ....
gi 922581565  2092 SPFK 2095
Cdd:pfam00630   86 SPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
216-300 9.27e-18

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 80.34  E-value: 9.27e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    216 KVRLEPLGGGVPKQPVQFYVDAVEAGKGQLEISV---NQGKVPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGC 292
Cdd:smart00557    5 KASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*...
gi 922581565    293 PIKVEILP 300
Cdd:smart00557   85 PFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1243-1332 5.78e-17

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 78.03  E-value: 5.78e-17
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1243 PAKTTVSkIPSL--SRVGQPSSLVVEVS--GHDQLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGV 1318
Cdd:smart00557    1 ASKVKAS-GPGLekGVVGEPAEFTVDTRdaGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGE 79
                            90
                    ....*....|....
gi 922581565   1319 PVTGSPFTCRAYDP 1332
Cdd:smart00557   80 HIPGSPFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1522-1601 1.72e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.72e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1522 NAVVGKPATFVIDAARSGAGNMEI-IVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNGISVPGSPLICSVSS 1600
Cdd:smart00557   13 KGVVGEPAEFTVDTRDAGGGELEVeVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92

                    .
gi 922581565   1601 A 1601
Cdd:smart00557   93 A 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
124-209 1.80e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 76.87  E-value: 1.80e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    124 YSELSGPGLVRAPVNRTAQFDITGEGLELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVD 203
Cdd:smart00557    3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                    ....*.
gi 922581565    204 GSPLSV 209
Cdd:smart00557   83 GSPFTV 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1839-1920 8.32e-16

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.95  E-value: 8.32e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1839 KREIVGEQTELKILIDSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPFPIHVL 1918
Cdd:smart00557   12 EKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91

                    ..
gi 922581565   1919 DP 1920
Cdd:smart00557   92 PA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2197-2284 1.34e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 74.18  E-value: 1.34e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   2197 VYGAAVDQSIkIGEPASLIFDPKKTNGG-LKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGS 2275
Cdd:smart00557    6 ASGPGLEKGV-VGEPAEFTVDTRDAGGGeLEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581565   2276 PFTVNVVDP 2284
Cdd:smart00557   85 PFTVKVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1920-2008 2.76e-15

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 73.41  E-value: 2.76e-15
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1920 PSAVRV--IGLKNAPVGVEQQFSVDYTNSGASIASVEVRHGDQT-IPITVKKMKPGQLLCTFTPFVDGPHQVEVIIDGVP 1996
Cdd:smart00557    1 ASKVKAsgPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKkVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80
                            90
                    ....*....|..
gi 922581565   1997 LSDGPYEVFISH 2008
Cdd:smart00557   81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1429-1512 1.22e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 71.48  E-value: 1.22e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   1429 LERIPVDEETEIQILT-DEIDSAPEARVRDPQGNDLPVNVtRSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFTA 1507
Cdd:smart00557   11 LEKGVVGEPAEFTVDTrDAGGGELEVEVTGPSGKKVPVEV-KDNGDGT-YTVSYTPTEPGDYTVTVKFGGEHIPGSPFTV 88

                    ....*
gi 922581565   1508 KAYDA 1512
Cdd:smart00557   89 KVGPA 93
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
31-109 2.35e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 70.71  E-value: 2.35e-14
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565     31 IQPSKLHTDHSFEIDASAAGSGNLEIMI---NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWKLPV 107
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAGGGELEVEVtgpSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKV 90

                    ..
gi 922581565    108 ED 109
Cdd:smart00557   91 GP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2197-2278 5.23e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 5.23e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2197 VYGAAVDQSiKIGEPASLIFDPKKTNGGLKIHATGPDGQKVHHNVMRRPNGTSEVVFYPEETGTYNVSIDFNNRPITGSP 2276
Cdd:pfam00630    9 ASGPGLEPG-VVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581565  2277 FT 2278
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1509-1593 1.14e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.85  E-value: 1.14e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1509 AYDARKTVLVPPA--NAVVGKPATFVIDAARSGAGNMEIIVSVDNRNVPNFVQAEGQARFKVSFTPQDAKDHTISVKFNG 1586
Cdd:pfam00630    1 AADASKVKASGPGlePGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80

                   ....*..
gi 922581565  1587 ISVPGSP 1593
Cdd:pfam00630   81 QHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
2421-2505 1.53e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 68.47  E-value: 1.53e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2421 SRIMVRGDGLHRAVLKEHNEFIIDGSDinKEGRITATLLGSK-ADIPVRIQQLGHNVYKATYTPLTGGTYELHILWNGKH 2499
Cdd:pfam00630    5 SKVKASGPGLEPGVVGKPAEFTVDTRD--AGGEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQH 82

                   ....*.
gi 922581565  2500 VKGSPF 2505
Cdd:pfam00630   83 IPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1329-1412 2.82e-13

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 67.70  E-value: 2.82e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1329 AYDPAKIKVG--AIPKGLLDKPVYFTVDASEAGvGNLEVAVCE---GRVPSMAHALGHHKYDISFVPKEDVDHTITVRFN 1403
Cdd:pfam00630    1 AADASKVKASgpGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGpdgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*....
gi 922581565  1404 NEPVPGSPF 1412
Cdd:pfam00630   80 GQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
216-295 2.79e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 64.62  E-value: 2.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   216 KVRLEPLGGGVPKQPVQFYVDAVEA-GKGQLEISVNQGK-VPNNVQMQGAGRCLVTFIPQHAGTYVIDVTFNGEQVHGCP 293
Cdd:pfam00630    8 KASGPGLEPGVVGKPAEFTVDTRDAgGEGEVEVTGPDGSpVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSP 87

                   ..
gi 922581565   294 IK 295
Cdd:pfam00630   88 FK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1917-2003 4.68e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 64.23  E-value: 4.68e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1917 VLDPSAVRV--IGLKNAPVGVEQQFSVDYTNSGASiASVEVRHGD-QTIPITVKKMKPGQLLCTFTPFVDGPHQVEVIID 1993
Cdd:pfam00630    1 AADASKVKAsgPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79
                           90
                   ....*....|
gi 922581565  1994 GVPLSDGPYE 2003
Cdd:pfam00630   80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
125-206 8.81e-12

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 63.46  E-value: 8.81e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565   125 SELSGPGLVRAPVNRTAQFDITGEGlELSDIQAKISGPDNREYPIRIIPRSSGKYTAEYEIEQVGEHHLTVWIAGRKVDG 204
Cdd:pfam00630    7 VKASGPGLEPGVVGKPAEFTVDTRD-AGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85

                   ..
gi 922581565   205 SP 206
Cdd:pfam00630   86 SP 87
Filamin pfam00630
Filamin/ABP280 repeat;
1083-1173 1.76e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 62.31  E-value: 1.76e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  1083 VYDASEIIV-GEIPNQSNLNDTVEFTVDAGRAGfGNLEMAIKDADGVIIPSHVAQLESGSakFLVTFTPATKGPHTVNIT 1161
Cdd:pfam00630    1 AADASKVKAsGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGT--YTVSYTPTEPGDYTVSVK 77
                           90
                   ....*....|..
gi 922581565  1162 FNKEVLKNSPFE 1173
Cdd:pfam00630   78 FNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1256-1326 1.13e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.00  E-value: 1.13e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1256 RVGQPSSLVVEVSGHD-QLEIRVLDSKKSEIGTDIVEIEPGHMQINFTPAQVGDHEIDVRYGGVPVTGSPFT 1326
Cdd:pfam00630   18 VVGKPAEFTVDTRDAGgEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
1429-1506 2.47e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.22  E-value: 2.47e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581565  1429 LERIPVDEETEIQILTDEIDSAPEARVRDPQGNDLPVNVTrSRENETlHIATYVPKCVGNHLIDIFLQGEPIAGSPFT 1506
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVT-DNGDGT-YTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2118-2191 3.46e-10

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 58.77  E-value: 3.46e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 922581565   2118 ATTINVDRRNAGNGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVAGFQIPGYPQTILVSE 2191
Cdd:smart00557   19 PAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
2526-2601 4.66e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 58.45  E-value: 4.66e-10
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 922581565  2526 LKIGIINENIKTLIDTRRAGsGQLSALCMGPN-KPAYCELYDHRDGTYALCVRPAEIGKHTLVIKYDDEHVKGSPFV 2601
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
2098-2184 9.41e-10

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 57.68  E-value: 9.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2098 VIDPKNVEIRGLS-DQVLLRHATTINVDRRNAGnGELQVEITDPTGSPLRTEMLKSPGGEDRITFLPNQTGPHKINVKVA 2176
Cdd:pfam00630    1 AADASKVKASGPGlEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                   ....*...
gi 922581565  2177 GFQIPGYP 2184
Cdd:pfam00630   80 GQHIPGSP 87
Filamin pfam00630
Filamin/ABP280 repeat;
31-104 2.31e-09

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 56.53  E-value: 2.31e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565    31 IQPSKLHTDHSFEIDAS-AAGSGNLEIMI-NGGRVPCRVRELGSRQYMAIFTPTQSMTHTIEMRFNGEHVSGSPWK 104
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRdAGGEGEVEVTGpDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
2303-2379 3.26e-09

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 56.07  E-value: 3.26e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 922581565   2303 RLGHSNSFDVDATAAGPGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKYSIYLYWNELPVE-SAFPVRA 2379
Cdd:smart00557   15 VVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVP--VEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPgSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
2281-2371 2.43e-08

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 53.45  E-value: 2.43e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  2281 VVDPTKVIVNDLDMDRDgtlllRLGHSNSFDVDATAAGpGKLRAEVRDADSSLIGngPVVEDMGQGKYRVRFNPDQPGKY 2360
Cdd:pfam00630    1 AADASKVKASGPGLEPG-----VVGKPAEFTVDTRDAG-GEGEVEVTGPDGSPVP--VEVTDNGDGTYTVSYTPTEPGDY 72
                           90
                   ....*....|.
gi 922581565  2361 SIYLYWNELPV 2371
Cdd:pfam00630   73 TVSVKFNGQHI 83
Filamin pfam00630
Filamin/ABP280 repeat;
1842-1913 1.25e-07

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 51.52  E-value: 1.25e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1842 IVGEQTELKILIdSGVESQVEVIIEGPDREDNEVFVKKVSETLWSAVWTPKVEGEHELSILVAGEQIPGSPF 1913
Cdd:pfam00630   18 VVGKPAEFTVDT-RDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1754-1817 4.62e-07

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 49.91  E-value: 4.62e-07
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565   1754 AGQKYSFDVNSDD--KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPI 1817
Cdd:smart00557   16 VGEPAEFTVDTRDagGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81
Filamin pfam00630
Filamin/ABP280 repeat;
1754-1818 1.70e-06

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 48.44  E-value: 1.70e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565  1754 AGQKYSFDVNSDD-KNKVRVTIREPSGRMLPVQMEDLPDGGVRVSCRFKEVGIHSIDVFVDDQPIG 1818
Cdd:pfam00630   19 VGKPAEFTVDTRDaGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIP 84
PTZ00121 PTZ00121
MAEBL; Provisional
671-1093 1.91e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  671 KKPNVPKKRATTPEGHVEPVNDNEEKDRQAFLRTQSEKVFEPVDAPLRRSDEKESIYDLPPQERLHKYPEEPTIALGEKA 750
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  751 NTSAIAAYTKGRQDDI---DEVSRNASFPSAPTINYNERSDEVSNYNRTKEDHYGVVGEYPTAPKIaysdsKEAVIREHY 827
Cdd:PTZ00121 1524 ADEAKKAEEAKKADEAkkaEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVM 1598
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  828 AQAKEDPYATVGECPPAPEISLRSDKLNETKNEYRRTTDSDQQDGKagppppviEISKAEQARRTEEYLRV-------KS 900
Cdd:PTZ00121 1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--------EKKKAEELKKAEEENKIkaaeeakKA 1670
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  901 EDDKILAKHgfTRKPEpsiEIQEPVTEQIRDDVVETAIAPEV------------PLRPVEELPHSPAPSSRSTPATTPKL 968
Cdd:PTZ00121 1671 EEDKKKAEE--AKKAE---EDEKKAAEALKKEAEEAKKAEELkkkeaeekkkaeELKKAEEENKIKAEEAKKEAEEDKKK 1745
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565  969 SAKFRKDGKEGKPFDFGKSKFVCKHDVIKRGKEVEVKlEGIKlgKEDQLRvvvlppankaipganggpPTEVDTKVKKSS 1048
Cdd:PTZ00121 1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELD--EEDEKR------------------RMEVDKKIKDIF 1804
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 922581565 1049 SKYEIsfkpTEVGTHKVFAYVNDMQHPLSPFAVRVYDASEIIVGE 1093
Cdd:PTZ00121 1805 DNFAN----IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
999-1086 5.10e-05

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 44.13  E-value: 5.10e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581565    999 GKEVEVKLEGIKLGkEDQLRVVVLPPANKaipganggpptEVDTKVK-KSSSKYEISFKPTEVGTHKVFAYVNDMQHPLS 1077
Cdd:smart00557   17 GEPAEFTVDTRDAG-GGELEVEVTGPSGK-----------KVPVEVKdNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGS 84

                    ....*....
gi 922581565   1078 PFAVRVYDA 1086
Cdd:smart00557   85 PFTVKVGPA 93
Filamin pfam00630
Filamin/ABP280 repeat;
1029-1079 6.14e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 41.12  E-value: 6.14e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 922581565  1029 IPGANGGP-PTEVdtkVKKSSSKYEISFKPTEVGTHKVFAYVNDMQHPLSPF 1079
Cdd:pfam00630   40 VTGPDGSPvPVEV---TDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
1666-1730 7.69e-04

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 40.74  E-value: 7.69e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 922581565  1666 LNSAQIGQKKGFTIDNINKSSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEIYLD 1730
Cdd:pfam00630   14 LEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYtVSYTPTEPGDYTVSVKFN 79
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
1666-1733 8.33e-03

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 37.97  E-value: 8.33e-03
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 922581565   1666 LNSAQIGQKKGFTIDNINK-SSDCNVIITAPDGSMVPVSIQKSSTSAY-AEFTPTITGEHLVEI-YLDHEI 1733
Cdd:smart00557   11 LEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYtVSYTPTEPGDYTVTVkFGGEHI 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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