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Conserved domains on  [gi|398303820|ref|NP_001257647|]
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interferon induced transmembrane protein 7 [Mus musculus]

Protein Classification

CD225/dispanin family protein( domain architecture ID 10517436)

CD225/dispanin family protein similar to Homo sapiens tumor suppressor candidate 5 (TUSC5), which may be involved in fat metabolism, and synapse differentiation-inducing gene protein 1 (SynDIG1), which may regulate AMPA receptor content at nascent synapses and have a role in postsynaptic development and maturation. CD225 is an interferon-inducible transmembrane protein associated with interferon induced cell growth suppression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 33-99 1.62e-26

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


:

Pssm-ID: 461336  Cd Length: 68  Bit Score: 93.33  E-value: 1.62e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398303820   33 PDYVVWSLFNTLFmnfCCL--GFIAYAYSVKSRDRKMVGDMTGAQAFASTARCLNISCLILSVVMVILF 99
Cdd:pfam04505   3 PDYLVWSIFSTLC---CCLplGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
 
Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 33-99 1.62e-26

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


Pssm-ID: 461336  Cd Length: 68  Bit Score: 93.33  E-value: 1.62e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398303820   33 PDYVVWSLFNTLFmnfCCL--GFIAYAYSVKSRDRKMVGDMTGAQAFASTARCLNISCLILSVVMVILF 99
Cdd:pfam04505   3 PDYLVWSIFSTLC---CCLplGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
Pat_TGL3_like cd07229
Triacylglycerol lipase 3; Triacylglycerol lipase 3 (TGL3) are responsible for all the TAG ...
 65-86 9.90e-03

Triacylglycerol lipase 3; Triacylglycerol lipase 3 (TGL3) are responsible for all the TAG lipase activity of the lipid particle. Triacylglycerol (TAG) lipases are also necessary for the mobilization of TAG stored in lipid particles. TGL3 contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes. This family includes Tgl3p from Saccharomyces cerevisiae.


Pssm-ID: 132867  Cd Length: 391  Bit Score: 34.20  E-value: 9.90e-03
                         10        20
                 ....*....|....*....|..
gi 398303820  65 RKMVGDMTGAQAFASTARCLNI 86
Cdd:cd07229  194 RANLGDLTFEEAYARTGRVLNI 215
 
Name Accession Description Interval E-value
CD225 pfam04505
Interferon-induced transmembrane protein; This family includes the human leukocyte antigen ...
 33-99 1.62e-26

Interferon-induced transmembrane protein; This family includes the human leukocyte antigen CD225, which is an interferon inducible transmembrane protein, and is associated with interferon induced cell growth suppression.


Pssm-ID: 461336  Cd Length: 68  Bit Score: 93.33  E-value: 1.62e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398303820   33 PDYVVWSLFNTLFmnfCCL--GFIAYAYSVKSRDRKMVGDMTGAQAFASTARCLNISCLILSVVMVILF 99
Cdd:pfam04505   3 PDYLVWSIFSTLC---CCLplGIVAIVYSVKVRDRKAAGDYEGAQRASRTAKCLNIIALVLGLVVIILY 68
Pat_TGL3_like cd07229
Triacylglycerol lipase 3; Triacylglycerol lipase 3 (TGL3) are responsible for all the TAG ...
 65-86 9.90e-03

Triacylglycerol lipase 3; Triacylglycerol lipase 3 (TGL3) are responsible for all the TAG lipase activity of the lipid particle. Triacylglycerol (TAG) lipases are also necessary for the mobilization of TAG stored in lipid particles. TGL3 contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes. This family includes Tgl3p from Saccharomyces cerevisiae.


Pssm-ID: 132867  Cd Length: 391  Bit Score: 34.20  E-value: 9.90e-03
                         10        20
                 ....*....|....*....|..
gi 398303820  65 RKMVGDMTGAQAFASTARCLNI 86
Cdd:cd07229  194 RANLGDLTFEEAYARTGRVLNI 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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