|
Name |
Accession |
Description |
Interval |
E-value |
| COG5028 |
COG5028 |
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking ... |
395-1190 |
3.00e-168 |
|
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion];
Pssm-ID: 227361 [Multi-domain] Cd Length: 861 Bit Score: 521.27 E-value: 3.00e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 395 QPGRPGFNQPPMPGAGNMYQQAPQ-ARRLDPDQMPNPI-QVMIENQRLSGGPFVTNQPGLLPPLVTTKFVVHDQGNSSPR 472
Cdd:COG5028 72 NNPAPSVMSPAFQSQQKFSSPYGGsMADGTAPKPTNPLvPVDLFEDQPPPISDLFLPPPPIVPPLTTNFVGSEQSNCSPK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 473 FLRSSLYCIPNTGDLLKTTALPLTLNISPLAKVGEGEMEPPIVNFGEmgPIRCNRCKAYMSPNMQFVDAGRRFQCLMCKV 552
Cdd:COG5028 152 YVRSTMYAIPETNDLLKKSKIPFGLVIRPFLELYPEEDPVPLVEDGS--IVRCRRCRSYINPFVQFIEQGRKWRCNICRS 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 553 TSEVHQNYYQHLDHTGQRVDKHERPELLLGTYEFLATKDYCRNNTPPevPAFIFIIDVSYNTVKSGLVHLLCSQIKNILK 632
Cdd:COG5028 230 KNDVPEGFDNPSGPNDPRSDRYSRPELKSGVVDFLAPKEYSLRQPPP--PVYVFLIDVSFEAIKNGLVKAAIRAILENLD 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 633 HLPVDQGqdksKVRVGFITYNSTVHFYNIKSSLaQPQMMVVGDVQEMFMPLLDGFLCHPEESAAVI-DALMEEIPRMFAD 711
Cdd:COG5028 308 QIPNFDP----RTKIAIICFDSSLHFFKLSPDL-DEQMLIVSDLDEPFLPFPSGLFVLPLKSCKQIiETLLDRVPRIFQD 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 712 TKETETILYPAIQAGLEALKASnaAGKLLVFNSTLPiAEAPGKLKNRDDrkllgtdKEKTVLTPQTTAYNTLGQECVQQG 791
Cdd:COG5028 383 NKSPKNALGPALKAAKSLIGGT--GGKIIVFLSTLP-NMGIGKLQLRED-------KESSLLSCKDSFYKEFAIECSKVG 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 792 CSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQAD--VDGKRLIQDIIKNVSRPIAFDAVMRVRTSAGIRPTEFYGH 869
Cdd:COG5028 453 ISVDLFLTSEDYIDVATLSHLCRYTGGQTYFYPNFSATrpNDATKLANDLVSHLSMEIGYEAVMRVRCSTGLRVSSFYGN 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 870 FFMSNTTDVELASIDATKSISIEIKHDDKLApEENVYLQVALLYTSCSGQRRLRILNLALRVTTTIADVFKCCDLDAMML 949
Cdd:COG5028 533 FFNRSSDLCAFSTMPRDTSLLVEFSIDEKLM-TSDVYFQVALLYTLNDGERRIRVVNLSLPTSSSIREVYASADQLAIAC 611
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 950 FFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISGGSdMTLDDRS 1029
Cdd:COG5028 612 ILAKKASTKALNSSLKEARVLINKSMVDILKAYKKELVKSNTSTQLPLPANLKLLPLLMLALLKSSAFRSGS-TPSDIRI 690
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1030 YVIQFILSMDLNQSVSYLYPRFIPIHNVVPE-------ETDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFV 1102
Cdd:COG5028 691 SALNRLTSLPLKQLMRNIYPTLYALHDMPIEaglpdegLLVLPSPINATSSLLESGGLYLIDTGQKIFLWFGKDAVPSLL 770
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1103 QSVFGVQGLQQIALERFNIVPE-TPLAKRIHGILEQImkeRSRYMRITW----LRQN--DKLESVFRHFLVEDRgTDGSA 1175
Cdd:COG5028 771 QDLFGVDSLSDIPSGKFTLPPTgNEFNERVRNIIGEL---RSVNDDSTLplvlVRGGgdPSLRLWFFSTLVEDK-TLNIP 846
|
810
....*....|....*
gi 442625389 1176 SYVDFLCHMHKEIKD 1190
Cdd:COG5028 847 SYLDYLQILHEKIKS 861
|
|
| Sec24-like |
cd01479 |
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the ... |
599-847 |
8.78e-121 |
|
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes of vesicular carriers within the endocytic and the biosynthetic pathways are COP- and clathrin-coated vesicles. Formation of COPII vesicles requires the ordered assembly of the coat built from several cytosolic components GTPase Sar1, complexes of Sec23-Sec24 and Sec13-Sec31. The process is initiated by the conversion of GDP to GTP by the GTPase Sar1 which then recruits the heterodimeric complex of Sec23 and Sec24. This heterodimeric complex generates the pre-budding complex. The final step leading to membrane deformation and budding of COPII-coated vesicles is carried by the heterodimeric complex Sec13-Sec31. The members of this CD belong to the Sec23-like family. Sec 24 is very similar to Sec23. The Sec23 and Sec24 polypeptides fold into five distinct domains: a beta-barrel, a zinc finger, a vWA or trunk, an all helical region and a carboxy Gelsolin domain. The members of this subgroup carry a partial MIDAS motif and have the overall Para-Rossmann type fold that is characteristic of this superfamily.
Pssm-ID: 238756 [Multi-domain] Cd Length: 244 Bit Score: 373.53 E-value: 8.78e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 599 PEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQgqdkSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQE 678
Cdd:cd01479 1 PQPAVYVFLIDVSYNAIKSGLLATACEALLSNLDNLPGDD----PRTRVGFITFDSTLHFFNLKSSLEQPQMMVVSDLDD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 679 MFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKasNAAGKLLVFNSTLPIAEApGKLKNR 758
Cdd:cd01479 77 PFLPLPDGLLVNLKESRQVIEDLLDQIPEMFQDTKETESALGPALQAAFLLLK--ETGGKIIVFQSSLPTLGA-GKLKSR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 759 DDRKLLGTDKEKTVLTPQTTAYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYT--YFQADVDGKRLI 836
Cdd:cd01479 154 EDPKLLSTDKEKQLLQPQTDFYKKLALECVKSQISVDLFLFSNQYVDVATLGCLSRLTGGQVYYYPsfNFSAPNDVEKLV 233
|
250
....*....|.
gi 442625389 837 QDIIKNVSRPI 847
Cdd:cd01479 234 NELARYLTRKI 244
|
|
| Sec23_trunk |
pfam04811 |
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum ... |
599-843 |
1.75e-109 |
|
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is known as the trunk domain and has an alpha/beta vWA fold and forms the dimer interface.
Pssm-ID: 398467 [Multi-domain] Cd Length: 241 Bit Score: 343.08 E-value: 1.75e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 599 PEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDqgqdkSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQE 678
Cdd:pfam04811 1 PQPPVFLFVIDVSYNAIKSGLLAALKESLLQSLDLLPGD-----PRARVGFITFDSTVHFFNLGSSLRQPQMLVVSDLQD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 679 MFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKASNAAGKLLVFNSTLPIAEAPGKLKNR 758
Cdd:pfam04811 76 MFLPLPDRFLVPLSECRFVLEDLLEQLPPMFPVTKRPERCLGPALQAAFLLLKAAFTGGKIMVFQGGLPTVGPGGKLKSR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 759 DDRKLLGTDKEKTVLTPQTT-AYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLIQ 837
Cdd:pfam04811 156 LDESHHGTDKEKAKLVKKADkFYKSLAKECVKQGHSVDLFAFSLDYVDVATLGQLSRLTGGQVYLYPSFQADVDGSKFKQ 235
|
....*.
gi 442625389 838 DIIKNV 843
Cdd:pfam04811 236 DLQRYF 241
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
586-1186 |
8.83e-51 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 197.22 E-value: 8.83e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 586 FLATKDYCRNNTPPevpAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQgqdkskVRVGFITYNSTVHFYNIKSSL 665
Cdd:PTZ00395 940 FLAKYPQVKNMLPP---YFVFVVECSYNAIYNNITYTILEGIRYAVQNVKCPQ------TKIAIITFNSSIYFYHCKGGK 1010
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 666 AQP-------------QMMVVGDVQEMFMPL-LDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALK 731
Cdd:PTZ00395 1011 GVSgeegdggggsgnhQVIVMSDVDDPFLPLpLEDLFFGCVEEIDKINTLIDTIKSVSTTMQSYGSCGNSALKIAMDMLK 1090
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 732 ASNAAGKLLVFNSTLPIAeAPGKLKNrddrklLGTDKEKTVL-TPQTTAYNTLGQECVQQGCSVDLFVF--NNAYIDLAT 808
Cdd:PTZ00395 1091 ERNGLGSICMFYTTTPNC-GIGAIKE------LKKDLQENFLeVKQKIFYDSLLLDLYAFNISVDIFIIssNNVRVCVPS 1163
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 809 IGQVSRLTGGEVFKYTYFQADVDGKRLIQDIIKNV-SRPIAFDAVMRVRTSAGIRPTEFyghfFMSNTTDVELASIDATK 887
Cdd:PTZ00395 1164 LQYVAQNTGGKILFVENFLWQKDYKEIYMNIMDTLtSEDIAYCCELKLRYSHHMSVKKL----FCCNNNFNSIISVDTIK 1239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 888 SIsiEIKHDDKLA----------PEENVYLQVALLYTSCSGQRRLRILNLALRVTTTIADVFKCCDLDAMMLFFAKQACF 957
Cdd:PTZ00395 1240 IP--KIRHDQTFAfllnysdiseSKKQIYFQCACIYTNLWGDRFVRLHTTHMNLTSSLSTVFRYTDAEALMNILIKQLCT 1317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 958 KLM--EHSPKQVKDNLihrsAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISggSDMTLDDRSYVIQFI 1035
Cdd:PTZ00395 1318 NILhnDNYSKIIIDNL----AAILFSYRINCASSAHSGQLILPDTLKLLPLFTSSLLKHNVTK--KEILHDLKVYSLIKL 1391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1036 LSMDLNQSVSYLYPRFIPIH--------NVVPEETDL--PTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFVQSV 1105
Cdd:PTZ00395 1392 LSMPIISSLLYVYPVMYVIHikgktneiDSMDVDDDLfiPKTIPSSAEKIYSNGIYLLDACTHFYLYFGFHSDANFAKEI 1471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1106 FGVQGLQQIALErFNIVpETPLAKRIHGILEQIMK--ERSRYMRITWLRQNDKLESVFRHFLVEDRGtDGSASYVDFLCH 1183
Cdd:PTZ00395 1472 VGDIPTEKNAHE-LNLT-DTPNAQKVQRIIKNLSRihHFNKYVPLVMVAPKSNEEEHLISLCVEDKA-DKEYSYVNFLCF 1548
|
...
gi 442625389 1184 MHK 1186
Cdd:PTZ00395 1549 IHK 1551
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
119-321 |
3.45e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 119 QFNSNAAPPPTNNNNAAFGAP----------PPTQAGSYVNGALPPSSTPQSVASGINQMSLNSATLAGLPHMPPPK-AA 187
Cdd:PRK12323 367 QSGGGAGPATAAAAPVAQPAPaaaapaaaapAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGpGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 188 TPGAAPGQPPIPAAGSTSQPPLPGQPPLPGQPPFSGQIPTSQPAPSPYGVPssrPGQPQLPPGATPPTYTQPGLPPQQQQ 267
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP---PWEELPPEFASPAPAQPDAAPAGWVA 523
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 442625389 268 GIPPLQQPGIPQQQPGFPPQQPGLPPLSQPGLPPQPGAPYGAPQQG--GYSGGFPG 321
Cdd:PRK12323 524 ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASasGLPDMFDG 579
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5028 |
COG5028 |
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking ... |
395-1190 |
3.00e-168 |
|
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion];
Pssm-ID: 227361 [Multi-domain] Cd Length: 861 Bit Score: 521.27 E-value: 3.00e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 395 QPGRPGFNQPPMPGAGNMYQQAPQ-ARRLDPDQMPNPI-QVMIENQRLSGGPFVTNQPGLLPPLVTTKFVVHDQGNSSPR 472
Cdd:COG5028 72 NNPAPSVMSPAFQSQQKFSSPYGGsMADGTAPKPTNPLvPVDLFEDQPPPISDLFLPPPPIVPPLTTNFVGSEQSNCSPK 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 473 FLRSSLYCIPNTGDLLKTTALPLTLNISPLAKVGEGEMEPPIVNFGEmgPIRCNRCKAYMSPNMQFVDAGRRFQCLMCKV 552
Cdd:COG5028 152 YVRSTMYAIPETNDLLKKSKIPFGLVIRPFLELYPEEDPVPLVEDGS--IVRCRRCRSYINPFVQFIEQGRKWRCNICRS 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 553 TSEVHQNYYQHLDHTGQRVDKHERPELLLGTYEFLATKDYCRNNTPPevPAFIFIIDVSYNTVKSGLVHLLCSQIKNILK 632
Cdd:COG5028 230 KNDVPEGFDNPSGPNDPRSDRYSRPELKSGVVDFLAPKEYSLRQPPP--PVYVFLIDVSFEAIKNGLVKAAIRAILENLD 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 633 HLPVDQGqdksKVRVGFITYNSTVHFYNIKSSLaQPQMMVVGDVQEMFMPLLDGFLCHPEESAAVI-DALMEEIPRMFAD 711
Cdd:COG5028 308 QIPNFDP----RTKIAIICFDSSLHFFKLSPDL-DEQMLIVSDLDEPFLPFPSGLFVLPLKSCKQIiETLLDRVPRIFQD 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 712 TKETETILYPAIQAGLEALKASnaAGKLLVFNSTLPiAEAPGKLKNRDDrkllgtdKEKTVLTPQTTAYNTLGQECVQQG 791
Cdd:COG5028 383 NKSPKNALGPALKAAKSLIGGT--GGKIIVFLSTLP-NMGIGKLQLRED-------KESSLLSCKDSFYKEFAIECSKVG 452
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 792 CSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQAD--VDGKRLIQDIIKNVSRPIAFDAVMRVRTSAGIRPTEFYGH 869
Cdd:COG5028 453 ISVDLFLTSEDYIDVATLSHLCRYTGGQTYFYPNFSATrpNDATKLANDLVSHLSMEIGYEAVMRVRCSTGLRVSSFYGN 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 870 FFMSNTTDVELASIDATKSISIEIKHDDKLApEENVYLQVALLYTSCSGQRRLRILNLALRVTTTIADVFKCCDLDAMML 949
Cdd:COG5028 533 FFNRSSDLCAFSTMPRDTSLLVEFSIDEKLM-TSDVYFQVALLYTLNDGERRIRVVNLSLPTSSSIREVYASADQLAIAC 611
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 950 FFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISGGSdMTLDDRS 1029
Cdd:COG5028 612 ILAKKASTKALNSSLKEARVLINKSMVDILKAYKKELVKSNTSTQLPLPANLKLLPLLMLALLKSSAFRSGS-TPSDIRI 690
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1030 YVIQFILSMDLNQSVSYLYPRFIPIHNVVPE-------ETDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFV 1102
Cdd:COG5028 691 SALNRLTSLPLKQLMRNIYPTLYALHDMPIEaglpdegLLVLPSPINATSSLLESGGLYLIDTGQKIFLWFGKDAVPSLL 770
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1103 QSVFGVQGLQQIALERFNIVPE-TPLAKRIHGILEQImkeRSRYMRITW----LRQN--DKLESVFRHFLVEDRgTDGSA 1175
Cdd:COG5028 771 QDLFGVDSLSDIPSGKFTLPPTgNEFNERVRNIIGEL---RSVNDDSTLplvlVRGGgdPSLRLWFFSTLVEDK-TLNIP 846
|
810
....*....|....*
gi 442625389 1176 SYVDFLCHMHKEIKD 1190
Cdd:COG5028 847 SYLDYLQILHEKIKS 861
|
|
| Sec24-like |
cd01479 |
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the ... |
599-847 |
8.78e-121 |
|
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes of vesicular carriers within the endocytic and the biosynthetic pathways are COP- and clathrin-coated vesicles. Formation of COPII vesicles requires the ordered assembly of the coat built from several cytosolic components GTPase Sar1, complexes of Sec23-Sec24 and Sec13-Sec31. The process is initiated by the conversion of GDP to GTP by the GTPase Sar1 which then recruits the heterodimeric complex of Sec23 and Sec24. This heterodimeric complex generates the pre-budding complex. The final step leading to membrane deformation and budding of COPII-coated vesicles is carried by the heterodimeric complex Sec13-Sec31. The members of this CD belong to the Sec23-like family. Sec 24 is very similar to Sec23. The Sec23 and Sec24 polypeptides fold into five distinct domains: a beta-barrel, a zinc finger, a vWA or trunk, an all helical region and a carboxy Gelsolin domain. The members of this subgroup carry a partial MIDAS motif and have the overall Para-Rossmann type fold that is characteristic of this superfamily.
Pssm-ID: 238756 [Multi-domain] Cd Length: 244 Bit Score: 373.53 E-value: 8.78e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 599 PEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQgqdkSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQE 678
Cdd:cd01479 1 PQPAVYVFLIDVSYNAIKSGLLATACEALLSNLDNLPGDD----PRTRVGFITFDSTLHFFNLKSSLEQPQMMVVSDLDD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 679 MFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKasNAAGKLLVFNSTLPIAEApGKLKNR 758
Cdd:cd01479 77 PFLPLPDGLLVNLKESRQVIEDLLDQIPEMFQDTKETESALGPALQAAFLLLK--ETGGKIIVFQSSLPTLGA-GKLKSR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 759 DDRKLLGTDKEKTVLTPQTTAYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYT--YFQADVDGKRLI 836
Cdd:cd01479 154 EDPKLLSTDKEKQLLQPQTDFYKKLALECVKSQISVDLFLFSNQYVDVATLGCLSRLTGGQVYYYPsfNFSAPNDVEKLV 233
|
250
....*....|.
gi 442625389 837 QDIIKNVSRPI 847
Cdd:cd01479 234 NELARYLTRKI 244
|
|
| Sec23_trunk |
pfam04811 |
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum ... |
599-843 |
1.75e-109 |
|
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is known as the trunk domain and has an alpha/beta vWA fold and forms the dimer interface.
Pssm-ID: 398467 [Multi-domain] Cd Length: 241 Bit Score: 343.08 E-value: 1.75e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 599 PEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDqgqdkSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQE 678
Cdd:pfam04811 1 PQPPVFLFVIDVSYNAIKSGLLAALKESLLQSLDLLPGD-----PRARVGFITFDSTVHFFNLGSSLRQPQMLVVSDLQD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 679 MFMPLLDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALKASNAAGKLLVFNSTLPIAEAPGKLKNR 758
Cdd:pfam04811 76 MFLPLPDRFLVPLSECRFVLEDLLEQLPPMFPVTKRPERCLGPALQAAFLLLKAAFTGGKIMVFQGGLPTVGPGGKLKSR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 759 DDRKLLGTDKEKTVLTPQTT-AYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLIQ 837
Cdd:pfam04811 156 LDESHHGTDKEKAKLVKKADkFYKSLAKECVKQGHSVDLFAFSLDYVDVATLGQLSRLTGGQVYLYPSFQADVDGSKFKQ 235
|
....*.
gi 442625389 838 DIIKNV 843
Cdd:pfam04811 236 DLQRYF 241
|
|
| trunk_domain |
cd01468 |
trunk domain. COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi ... |
599-838 |
7.16e-98 |
|
trunk domain. COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is known as the trunk domain and has an alpha/beta vWA fold and forms the dimer interface. Some members of this family possess a partial MIDAS motif that is a characteristic feature of most vWA domain proteins.
Pssm-ID: 238745 [Multi-domain] Cd Length: 239 Bit Score: 311.49 E-value: 7.16e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 599 PEVPAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDqgqdkSKVRVGFITYNSTVHFYNIKSSLAQPQMMVVGDVQE 678
Cdd:cd01468 1 PQPPVFVFVIDVSYEAIKEGLLQALKESLLASLDLLPGD-----PRARVGLITYDSTVHFYNLSSDLAQPKMYVVSDLKD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 679 MFMPLLDGFLCHPEESAAVIDALMEEIPRMFAD--TKETETILYPAIQAGLEALKASNAAGKLLVFNSTLPIAEaPGKLK 756
Cdd:cd01468 76 VFLPLPDRFLVPLSECKKVIHDLLEQLPPMFWPvpTHRPERCLGPALQAAFLLLKGTFAGGRIIVFQGGLPTVG-PGKLK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 757 NRDDRKLLGTDKEKTVLTPQTTAYNTLGQECVQQGCSVDLFVFNNAYIDLATIGQVSRLTGGEVFKYTYFQADVDGKRLI 836
Cdd:cd01468 155 SREDKEPIRSHDEAQLLKPATKFYKSLAKECVKSGICVDLFAFSLDYVDVATLKQLAKSTGGQVYLYDSFQAPNDGSKFK 234
|
..
gi 442625389 837 QD 838
Cdd:cd01468 235 QD 236
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
586-1186 |
8.83e-51 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 197.22 E-value: 8.83e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 586 FLATKDYCRNNTPPevpAFIFIIDVSYNTVKSGLVHLLCSQIKNILKHLPVDQgqdkskVRVGFITYNSTVHFYNIKSSL 665
Cdd:PTZ00395 940 FLAKYPQVKNMLPP---YFVFVVECSYNAIYNNITYTILEGIRYAVQNVKCPQ------TKIAIITFNSSIYFYHCKGGK 1010
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 666 AQP-------------QMMVVGDVQEMFMPL-LDGFLCHPEESAAVIDALMEEIPRMFADTKETETILYPAIQAGLEALK 731
Cdd:PTZ00395 1011 GVSgeegdggggsgnhQVIVMSDVDDPFLPLpLEDLFFGCVEEIDKINTLIDTIKSVSTTMQSYGSCGNSALKIAMDMLK 1090
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 732 ASNAAGKLLVFNSTLPIAeAPGKLKNrddrklLGTDKEKTVL-TPQTTAYNTLGQECVQQGCSVDLFVF--NNAYIDLAT 808
Cdd:PTZ00395 1091 ERNGLGSICMFYTTTPNC-GIGAIKE------LKKDLQENFLeVKQKIFYDSLLLDLYAFNISVDIFIIssNNVRVCVPS 1163
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 809 IGQVSRLTGGEVFKYTYFQADVDGKRLIQDIIKNV-SRPIAFDAVMRVRTSAGIRPTEFyghfFMSNTTDVELASIDATK 887
Cdd:PTZ00395 1164 LQYVAQNTGGKILFVENFLWQKDYKEIYMNIMDTLtSEDIAYCCELKLRYSHHMSVKKL----FCCNNNFNSIISVDTIK 1239
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 888 SIsiEIKHDDKLA----------PEENVYLQVALLYTSCSGQRRLRILNLALRVTTTIADVFKCCDLDAMMLFFAKQACF 957
Cdd:PTZ00395 1240 IP--KIRHDQTFAfllnysdiseSKKQIYFQCACIYTNLWGDRFVRLHTTHMNLTSSLSTVFRYTDAEALMNILIKQLCT 1317
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 958 KLM--EHSPKQVKDNLihrsAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISggSDMTLDDRSYVIQFI 1035
Cdd:PTZ00395 1318 NILhnDNYSKIIIDNL----AAILFSYRINCASSAHSGQLILPDTLKLLPLFTSSLLKHNVTK--KEILHDLKVYSLIKL 1391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1036 LSMDLNQSVSYLYPRFIPIH--------NVVPEETDL--PTPVRCTHEKTQEDGAYILENGVHLFVWLGQALSPDFVQSV 1105
Cdd:PTZ00395 1392 LSMPIISSLLYVYPVMYVIHikgktneiDSMDVDDDLfiPKTIPSSAEKIYSNGIYLLDACTHFYLYFGFHSDANFAKEI 1471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 1106 FGVQGLQQIALErFNIVpETPLAKRIHGILEQIMK--ERSRYMRITWLRQNDKLESVFRHFLVEDRGtDGSASYVDFLCH 1183
Cdd:PTZ00395 1472 VGDIPTEKNAHE-LNLT-DTPNAQKVQRIIKNLSRihHFNKYVPLVMVAPKSNEEEHLISLCVEDKA-DKEYSYVNFLCF 1548
|
...
gi 442625389 1184 MHK 1186
Cdd:PTZ00395 1549 IHK 1551
|
|
| Sec23_helical |
pfam04815 |
Sec23/Sec24 helical domain; COPII-coated vesicles carry proteins from the endoplasmic ... |
943-1044 |
1.39e-35 |
|
Sec23/Sec24 helical domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is composed of five alpha helices.
Pssm-ID: 461441 [Multi-domain] Cd Length: 103 Bit Score: 130.70 E-value: 1.39e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 943 DLDAMMLFFAKQACFKLMEHSPKQVKDNLIHRSAQILACYRKHCTSPTSAGQLILPECLKLLPLYASCLLKNDAISGGSD 1022
Cdd:pfam04815 1 DQEAIAVLLAKKAVEKALSSSLSDAREALDNKLVDILAAYRKYCASSSSPGQLILPESLKLLPLYMLALLKSPALRGGNS 80
|
90 100
....*....|....*....|..
gi 442625389 1023 MTLDDRSYVIQFILSMDLNQSV 1044
Cdd:pfam04815 81 SPSDERAYARHLLLSLPVEELL 102
|
|
| Sec23_BS |
pfam08033 |
Sec23/Sec24 beta-sandwich domain; |
848-932 |
1.46e-31 |
|
Sec23/Sec24 beta-sandwich domain;
Pssm-ID: 429794 [Multi-domain] Cd Length: 86 Bit Score: 118.41 E-value: 1.46e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 848 AFDAVMRVRTSAGIRPTEFYGHFFMSNTTD-VELASIDATKSISIEIKHDDKLAPEENVYLQVALLYTSCSGQRRLRILN 926
Cdd:pfam08033 1 GFNAVLRVRTSKGLKVSGFIGNFVSRSSGDtWKLPSLDPDTSYAFEFDIDEPLPNGSNAYIQFALLYTHSSGERRIRVTT 80
|
....*.
gi 442625389 927 LALRVT 932
Cdd:pfam08033 81 VALPVT 86
|
|
| Gelsolin |
pfam00626 |
Gelsolin repeat; |
1061-1135 |
1.74e-12 |
|
Gelsolin repeat;
Pssm-ID: 395501 [Multi-domain] Cd Length: 76 Bit Score: 63.87 E-value: 1.74e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442625389 1061 ETDLPTPVRCTHEKTQEDGAYILENGVHLFVWLGQalSPDFVQSVFGVQGLQQIALERFNIVPE---TPLAKRIHGIL 1135
Cdd:pfam00626 1 KFVLPPPVPLSQESLNSGDCYLLDNGFTIFLWVGK--GSSLLEKLFAALLAAQLDDDERFPLPEvirVPQGKEPARFL 76
|
|
| SEC23 |
COG5047 |
Vesicle coat complex COPII, subunit SEC23 [Intracellular trafficking and secretion]; |
496-1097 |
3.05e-12 |
|
Vesicle coat complex COPII, subunit SEC23 [Intracellular trafficking and secretion];
Pssm-ID: 227380 [Multi-domain] Cd Length: 755 Bit Score: 71.07 E-value: 3.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 496 TLNISPLAKVGEGEMEPPIVNFGEMGPIRCNR-CKAYMSPNMQfVDAGRRF-QCLMCkvtsevhqNYYQHLDHTGQRVDK 573
Cdd:COG5047 27 TRTVIPIACLYTPLHEDDALTVNYYEPVKCTApCKAVLNPYCH-IDERNQSwICPFC--------NQRNTLPPQYRDISN 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 574 HERPELLLGTYeflATKDYCRNNTPPEVPAFIFIIDVSYNTVKsglVHLLCSQIKNILKHLPVDqgqdkskVRVGFITYN 653
Cdd:COG5047 98 ANLPLELLPQS---STIEYTLSKPVILPPVFFFVVDACCDEEE---LTALKDSLIVSLSLLPPE-------ALVGLITYG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 654 STVHFYNIkSSLAQPQMMVVGDVQEMFMPLLDGFLCHPEES------AAVIDALMEEIPRMFADTKETETILYPAIQ--- 724
Cdd:COG5047 165 TSIQVHEL-NAENHRRSYVFSGNKEYTKENLQELLALSKPTksggfeSKISGIGQFASSRFLLPTQQCEFKLLNILEqlq 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 725 ---------------AGLeALKAS---------NAAGKLLVFNSTlPIAEAPGKLKNRDDRK------LLGTDKEKTVlT 774
Cdd:COG5047 244 pdpwpvpagkrplrcTGS-ALNIAsslleqcfpNAGCHIVLFAGG-PCTVGPGTVVSTELKEpmrshhDIESDSAQHS-K 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 775 PQTTAYNTLGQECVQQGCSVDLFVfnnAYIDLATIGQVSRL---TGGEVFKYTYFQADvdgkRLIQDIIKNVSR------ 845
Cdd:COG5047 321 KATKFYKGLAERVANQGHALDIFA---GCLDQIGIMEMEPLttsTGGALVLSDSFTTS----IFKQSFQRIFNRdsegyl 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 846 PIAFDAVMRVRTSAGIRPTEFYGH---------------FFMSNTTDVELASIDATKSISI------EIKHDDKLAPEEn 904
Cdd:COG5047 394 KMGFNANMEVKTSKNLKIKGLIGHavsvkkkannisdseIGIGATNSWKMASLSPKSNYALyfeialGAASGSAQRPAE- 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 905 VYLQVALLYTSCSGQRRLRILNLALRVTTTIADV-FKCCDLDAMMLFFAKQACFKLMEHSPKQV----KDNLIhRSAQIL 979
Cdd:COG5047 473 AYIQFITTYQHSSGTYRIRVTTVARMFTDGGLPKiNRSFDQEAAAVFMARIAAFKAETEDIIDVfrwiDRNLI-RLCQKF 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 980 ACYRKhcTSPTSAGqliLPECLKLLPLYASCLLKNDAISGGSDmTLDDRSYVIQFILSMDLNQSVSYLYPRFIPIH---N 1056
Cdd:COG5047 552 ADYRK--DDPSSFR---LDPNFTLYPQFMYHLRRSPFLSVFNN-SPDETAFYRHMLNNADVNDSLIMIQPTLQSYSfekG 625
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 442625389 1057 VVPEETDLPTpvrcthekTQEDGAYILENGVHLFVWLGQAL 1097
Cdd:COG5047 626 GVPVLLDSVS--------VKPDVILLLDTFFHILIFHGSYI 658
|
|
| zf-Sec23_Sec24 |
pfam04810 |
Sec23/Sec24 zinc finger; COPII-coated vesicles carry proteins from the endoplasmic reticulum ... |
522-559 |
2.89e-11 |
|
Sec23/Sec24 zinc finger; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is found to be zinc binding domain.
Pssm-ID: 461437 [Multi-domain] Cd Length: 38 Bit Score: 59.00 E-value: 2.89e-11
10 20 30
....*....|....*....|....*....|....*...
gi 442625389 522 PIRCNRCKAYMSPNMQFVDAGRRFQCLMCKVTSEVHQN 559
Cdd:pfam04810 1 PVRCRRCRAYLNPFCQFDFGGKKWTCNFCGTRNPVPPE 38
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
119-321 |
3.45e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 3.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 119 QFNSNAAPPPTNNNNAAFGAP----------PPTQAGSYVNGALPPSSTPQSVASGINQMSLNSATLAGLPHMPPPK-AA 187
Cdd:PRK12323 367 QSGGGAGPATAAAAPVAQPAPaaaapaaaapAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGpGG 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 188 TPGAAPGQPPIPAAGSTSQPPLPGQPPLPGQPPFSGQIPTSQPAPSPYGVPssrPGQPQLPPGATPPTYTQPGLPPQQQQ 267
Cdd:PRK12323 447 APAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPP---PWEELPPEFASPAPAQPDAAPAGWVA 523
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 442625389 268 GIPPLQQPGIPQQQPGFPPQQPGLPPLSQPGLPPQPGAPYGAPQQG--GYSGGFPG 321
Cdd:PRK12323 524 ESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASasGLPDMFDG 579
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
124-320 |
2.40e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 124 AAPPPTNNNNAAFGAPPPTQAGSYVNGALPPS----STPQSVASGINQMSLNSATLAGLphMPPPKAATPgAAPGQPPIP 199
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSpwdpADPPAAVLAPAAALPPAASPAGP--LPPPTSAQP-TAPPPPPGP 2845
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 200 AAGSTSQPPLPGQPPLpgqppFSGQIPTSQPAPSPYG---VPSSRPGQPQLPPgatPPTYTQPGLPPQQQQGIPPLQQPG 276
Cdd:PHA03247 2846 PPPSLPLGGSVAPGGD-----VRRRPPSRSPAAKPAAparPPVRRLARPAVSR---STESFALPPDQPERPPQPQAPPPP 2917
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 442625389 277 IPQQQPGFPPQQPGLPPlsQPGLPPQPGAPYGAPQ-QGGYSGGFP 320
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPP--PPPRPQPPLAPTTDPAgAGEPSGAVP 2960
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
125-424 |
2.70e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 125 APPPTNnnnAAFGAPPPTQAGSYVNGALPPSSTPQSVASGiNQMSLNSATLAGLPHMPPPKAATPGAAPGQPPIPAAGST 204
Cdd:PHA03247 2711 APHALV---SATPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 205 SQPPLPGQPPLPGQPPFSGQIPTSQPAPSPYGVPSSRPGQPQLPPGATPPTytqpglppqqqqgipplqqpgipqqqpgf 284
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPT----------------------------- 2837
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 285 ppqqpglpplsQPGLPPQPGAPYGAPQQGGYSGG-----FPGQAPGGFPGAPPPLPGQQAAAPPqfgAPQPGYPGQQPGY 359
Cdd:PHA03247 2838 -----------APPPPPGPPPPSLPLGGSVAPGGdvrrrPPSRSPAAKPAAPARPPVRRLARPA---VSRSTESFALPPD 2903
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442625389 360 PPQPGQQPMPGYPPQPGQQLGGPGYPPQPGAgFPGQPgrpgfNQPPMPGAGNMYQQAPQARRLDP 424
Cdd:PHA03247 2904 QPERPPQPQAPPPPQPQPQPPPPPQPQPPPP-PPPRP-----QPPLAPTTDPAGAGEPSGAVPQP 2962
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
133-254 |
4.71e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.12 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442625389 133 NAAFGAPPPTQAGSYVNGALPPSSTPQSVAsginqmslnsatlAGLPHMPPPKAATPGAAPGQPPIPAAGSTSQPPLPGQ 212
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAA-------------APAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGG 452
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 442625389 213 PPLPGQPPFSGQIPTSQPAPSPYGVPSSRPGQPQLPPGATPP 254
Cdd:PRK07764 453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494
|
|
| |
