DNA polymerase interacting tpr containing protein of 47kD, isoform B [Drosophila melanogaster]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
CTWD_Cns1 | cd21380 | C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and ... |
232-387 | 6.07e-53 | |||
C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and similar proteins; Cns1, also called cyclophilin seven suppressor 1, or STI1 stress-inducible protein homolog, binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1). It stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. It is involved in only a subset of Hsp90 functions. The model corresponds to Cns1 C-terminal wheel domain consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. : Pssm-ID: 439174 Cd Length: 153 Bit Score: 173.13 E-value: 6.07e-53
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3a0801s09 super family | cl36792 | mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ... |
84-179 | 3.25e-08 | |||
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines] The actual alignment was detected with superfamily member TIGR00990: Pssm-ID: 273380 [Multi-domain] Cd Length: 615 Bit Score: 55.38 E-value: 3.25e-08
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Name | Accession | Description | Interval | E-value | ||||
CTWD_Cns1 | cd21380 | C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and ... |
232-387 | 6.07e-53 | ||||
C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and similar proteins; Cns1, also called cyclophilin seven suppressor 1, or STI1 stress-inducible protein homolog, binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1). It stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. It is involved in only a subset of Hsp90 functions. The model corresponds to Cns1 C-terminal wheel domain consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. Pssm-ID: 439174 Cd Length: 153 Bit Score: 173.13 E-value: 6.07e-53
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Wheel | pfam18972 | Cns1/TTC4 Wheel domain; The wheel domain is found at the C-terminus of yeast Cns1 and human ... |
280-388 | 5.38e-16 | ||||
Cns1/TTC4 Wheel domain; The wheel domain is found at the C-terminus of yeast Cns1 and human TTC4 proteins. The structure of the domain shows an overall fold consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. The Hsp90 chaperone machinery in eukaryotes comprises a number of distinct accessory factors. Cns1 is one of the few essential co-chaperones in yeast. Cns1 is important for maintaining translation elongation, specifically chaperoning the elongation factor eEF2. In this context, Cns1 interacts with the novel co-factor Hgh1 and forms a quaternary complex together with eEF2 and Hsp90. Pssm-ID: 436877 Cd Length: 114 Bit Score: 73.41 E-value: 5.38e-16
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3a0801s09 | TIGR00990 | mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ... |
84-179 | 3.25e-08 | ||||
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines] Pssm-ID: 273380 [Multi-domain] Cd Length: 615 Bit Score: 55.38 E-value: 3.25e-08
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NlpI | COG4785 | Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
78-227 | 1.93e-07 | ||||
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 51.45 E-value: 1.93e-07
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Name | Accession | Description | Interval | E-value | ||||
CTWD_Cns1 | cd21380 | C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and ... |
232-387 | 6.07e-53 | ||||
C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1 and similar proteins; Cns1, also called cyclophilin seven suppressor 1, or STI1 stress-inducible protein homolog, binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1). It stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. It is involved in only a subset of Hsp90 functions. The model corresponds to Cns1 C-terminal wheel domain consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. Pssm-ID: 439174 Cd Length: 153 Bit Score: 173.13 E-value: 6.07e-53
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CTWD_Cns1-like | cd21377 | C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1, Homo ... |
233-386 | 4.77e-23 | ||||
C-terminal wheel domain found in Saccharomyces cerevisiae Hsp70/Hsp90 co-chaperone Cns1, Homo sapiens tetratricopeptide repeat protein 4 (TTC4), and similar proteins; The family includes Hsp70/Hsp90 co-chaperone Cns1 from Saccharomyces cerevisiae and the human Cns1 homolog tetratricopeptide repeat protein 4 (TTC4), both of which contain a C-terminal wheel domain consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. Cns1, also called cyclophilin seven suppressor 1, or STI1 stress-inducible protein homolog, binds to the molecular chaperones Hsp90 (HSC82 and HSP82) and Hsp70 (SSA1). It stimulates SSA1 ATPase activity, but not Hsp90 ATPase activity. It is involved in only a subset of Hsp90 functions. TTC4, also called TPR repeat protein 4, is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells. It interacts with TBK1 and promotes Sendai virus (SeV)-induced host cell innate immune responses. Pssm-ID: 439173 Cd Length: 159 Bit Score: 94.33 E-value: 4.77e-23
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Wheel | pfam18972 | Cns1/TTC4 Wheel domain; The wheel domain is found at the C-terminus of yeast Cns1 and human ... |
280-388 | 5.38e-16 | ||||
Cns1/TTC4 Wheel domain; The wheel domain is found at the C-terminus of yeast Cns1 and human TTC4 proteins. The structure of the domain shows an overall fold consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. The Hsp90 chaperone machinery in eukaryotes comprises a number of distinct accessory factors. Cns1 is one of the few essential co-chaperones in yeast. Cns1 is important for maintaining translation elongation, specifically chaperoning the elongation factor eEF2. In this context, Cns1 interacts with the novel co-factor Hgh1 and forms a quaternary complex together with eEF2 and Hsp90. Pssm-ID: 436877 Cd Length: 114 Bit Score: 73.41 E-value: 5.38e-16
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CTWD_TTC4 | cd21381 | C-terminal wheel domain found in Homo sapiens tetratricopeptide repeat protein 4 (TTC4) and ... |
268-388 | 5.50e-12 | ||||
C-terminal wheel domain found in Homo sapiens tetratricopeptide repeat protein 4 (TTC4) and similar proteins; TTC4, also called TPR repeat protein 4, is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells. It interacts with TBK1 and promotes Sendai virus (SeV)-induced host cell innate immune responses. The model corresponds to TTC4 C-terminal wheel domain consisting of a twisted five-stranded beta sheet surrounded by several alpha helices. Pssm-ID: 439175 Cd Length: 150 Bit Score: 63.30 E-value: 5.50e-12
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3a0801s09 | TIGR00990 | mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ... |
84-179 | 3.25e-08 | ||||
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines] Pssm-ID: 273380 [Multi-domain] Cd Length: 615 Bit Score: 55.38 E-value: 3.25e-08
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NlpI | COG4785 | Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
78-227 | 1.93e-07 | ||||
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 51.45 E-value: 1.93e-07
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TPR | COG0457 | Tetratricopeptide (TPR) repeat [General function prediction only]; |
83-262 | 2.18e-06 | ||||
Tetratricopeptide (TPR) repeat [General function prediction only]; Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 48.46 E-value: 2.18e-06
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NrfG | COG4235 | Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
76-202 | 8.15e-05 | ||||
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 41.92 E-value: 8.15e-05
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Spy | COG3914 | Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
75-203 | 3.64e-03 | ||||
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 39.59 E-value: 3.64e-03
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Blast search parameters | ||||
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