|
Name |
Accession |
Description |
Interval |
E-value |
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
184-901 |
0e+00 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 1235.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:TIGR02478 33 VYAIREGYQGLVDGGDNIEEAQWEDVRGILSLGGTIIGTARCKEFRERPGRLKAARNLVSNGIDALVVIGGDGSLTGADL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:TIGR02478 113 FREEWPSLLEELVDTGKITAEQAEEHRHLTIVGLVGSIDNDMCGTDMTIGADSALHRICEAIDAISSTAQSHQRAFVVEV 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQADWPDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERL 423
Cdd:TIGR02478 193 MGRHCGYLALMAAIATGADYVFIPERPPEEGWEDQLCHKLKRNRKAGKRKTIVIVAEGAIDRDLNPITSEDVKDVLVERL 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRW 503
Cdd:TIGR02478 273 GLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPETPSPVISLRGNKIVRKPLVEAVAQTKTVAKAIEEKDF 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 504 ADAVKLRGRSFERNLETYKMLTRLKPPKENFDADGKGIegyRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGV 583
Cdd:TIGR02478 353 DEAMRLRGREFAENLETFLFLSIPDDDKKLVPSEASRL---RIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGF 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 584 EGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFCI 663
Cdd:TIGR02478 430 SGLARHDVRELTWSDVEGWVGEGGSELGTNRSLPGDDLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDAAREKYPAFRI 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 664 PIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKF 743
Cdd:TIGR02478 510 PMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIKQSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGI 589
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 744 SIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMA 823
Cdd:TIGR02478 590 SLKDLQEDIEHLKETFAEGRAGKLILRNEKASKVYTTDFIARIISEEGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLA 669
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442623120 824 AKCVDWLAAQIKANIDANGVVNCksPDTATLLGIVSRQYRFSPLVD-LIAETNFDQRIPKKQWWLRLRPLLRILAKHDS 901
Cdd:TIGR02478 670 IRAVDFIEEKIKANKHADKLSAD--DTSAVVIGIRGSNVLFTPVKQlLANETDFEHRRPKNQWWLQLRPLVRILAGRDS 746
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
184-886 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 996.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:cd00764 36 VFFVYEGYEGLVKGGDYIKQAEWESVSNWLQEGGTIIGSARCKEFREREGRLQAAYNLIQRGITNLCVIGGDGSLTGADL 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWSSLLDELVKNKTITTEQQEKFNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:cd00764 116 FRSEWPSLLEELVKDGKITEEEVAKYQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRICEVVDAITTTAQSHQRTFVLEV 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQADWPDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERL 423
Cdd:cd00764 196 MGRHCGYLALVSGLATGADWIFIPERPPEDGWEDQMCRRLSEHRSRGKRLNIIIVAEGAIDDQLKPITSEDVKDLVVERL 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVAKAMAEKRW 503
Cdd:cd00764 276 GLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEATPDTPACVVSLNGNKAVRLPLMECVQLTKDVQKAMDEKRF 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 504 ADAVKLRGRSFERNLETYKML--TRLKPPKENfdadgkgiEGYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGIND 581
Cdd:cd00764 356 DEAAALRGKSFDKNWNLYKLLaiELPQPLPEK--------TNLNIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYD 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 582 GVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLPEGKFKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQF 661
Cdd:cd00764 428 GFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDLETIAYNFQKYGIDGLIIVGGFEAYKGLLQLREAREQYEEF 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 662 CIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEE 741
Cdd:cd00764 508 CIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEE 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 742 KFSIKDLQQDVYHMASKMAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTK 821
Cdd:cd00764 588 PFNIRDLQENVEHLTEKMKTTIGRGLVLRNEKCNENYTTVFTYELYSEEGKGVFDCRTNVLGHVQQGGAPSPFDRNFGTK 667
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442623120 822 MAAKCVDWLAAQIKANIdANGVVNCKSPDTATLLGIVSRQYRFSPlVDLIAETNFDQRIPKKQWW 886
Cdd:cd00764 668 FAVKAMKWIEQKLKENY-AAGNEFANDPDFNCVNGVKKYAVLFEP-VEELKQTTFEHRIPKEQWW 730
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
184-519 |
3.73e-137 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 412.85 E-value: 3.73e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:cd00363 33 VYGIYEGYAGLVEGD--IKELDWESVSDIINRGGTIIGSARCKEFRTEEGRAKAAENLKKHGIDALVVIGGDGSYTGADL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWSSLldelvknktitteqQEKFNVlhiVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:cd00363 111 LTEEWPSK--------------YQGFNV---IGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDTASSHQRTFVVEV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQADWPDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKVIDERL 423
Cdd:cd00363 174 MGRHCGDIALEAGLATGADIIFIPEEPAADEWEEEMVDVIKKRRERGKRHGIVIVAEGAIDFIPKPITEKLLAKLVEERL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSVPVVISLDGNQAVRVPLMECVERTQAVakamaekrw 503
Cdd:cd00363 254 GFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLNENQVVRHPLTEAVNMTKRV--------- 324
|
330
....*....|....*.
gi 442623120 504 adAVKLRGRSFERNLE 519
Cdd:cd00363 325 --GVDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
184-456 |
1.48e-115 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 353.95 E-value: 1.48e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:pfam00365 32 VYGIRNGYEGLVEGD--IDELTWRDVSGILNRGGTILGTSRSKPFKTEEGREKIAENLKKLGIDALVVIGGDGSLTGANK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWSslldelvknktitteqqekfnvLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:pfam00365 110 LSEERG----------------------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHNRVFVVEV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQadwPDRLVLKLEqERSAGQRLNIVIVAEGAMDreghpitAEDVKKVIDERL 423
Cdd:pfam00365 168 MGRHCGWLALMAGLAGGADAILIPEIPFD---IEELCEKIK-ELRKGKRFSIIVVAEGASD-------GEFLAKLIEEGT 236
|
250 260 270
....*....|....*....|....*....|...
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEA 456
Cdd:pfam00365 237 GIETRVTVLGHVQRGGTPSAFDRILATRLGVKA 269
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
545-828 |
1.74e-110 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 340.86 E-value: 1.74e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP---EGKF 621
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPfktEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 622 KEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQ 701
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 702 SAQGTkRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHmaskMAEGVSRGLILRNEKASEnysTD 781
Cdd:pfam00365 155 TASSH-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKE----LRKGKRFSIIVVAEGASD---GE 226
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 442623120 782 FIYRLYsEEGKGlFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVD 828
Cdd:pfam00365 227 FLAKLI-EEGTG-IETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
184-508 |
8.22e-106 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 330.50 E-value: 8.22e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:PRK03202 34 VYGIYDGYAGLLEGD--IVKLDLKSVSDIINRGGTILGSARFPEFKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FrqewsslldelvknktitTEqqEKFNVlhiVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:PRK03202 112 L------------------TE--HGIPV---IGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSHERVFIVEV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQadwPDRLVLKLEQERSAGQRLNIVIVAEGAMDreghpitAEDVKKVIDERL 423
Cdd:PRK03202 169 MGRHAGDLALHAGIAGGAEVILIPEVPFD---IEELCAKIKKGRERGKKHAIIVVAEGVMP-------AEELAKEIEERT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVISLDGNQAVRVPLMECVERTQAVAKamaeKRW 503
Cdd:PRK03202 239 GLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGG---RMVGIQNNKIVHVPIEEAVENMKHPFD----KDL 311
|
....*
gi 442623120 504 ADAVK 508
Cdd:PRK03202 312 YELAK 316
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
184-494 |
2.13e-98 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 312.01 E-value: 2.13e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:COG0205 34 VYGIRDGYEGLLEGD--IIDLTREDVSGILQRGGTILGSSRSKPFKTEEGREKALENLKKLGIDALVVIGGDGSLDGAAK 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWSslldelvknktitteqqekfnvLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:COG0205 112 LAEEYG----------------------IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAASHERVFVVEV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQadwPDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPI------------- 410
Cdd:COG0205 170 MGRHAGWLALAAGLAGGADLILIPEVPFD---LDKLLEKLKERRKRGKGYSIIVVAEGAGDEDGEAVleadtdafghvrl 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 411 --TAEDVKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVISLDGNQAVRVPLMECV 488
Cdd:COG0205 247 ggIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTG---VMVGIRRGEIVLVPLEEVA 323
|
....*.
gi 442623120 489 ERTQAV 494
Cdd:COG0205 324 NKEKPV 329
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
184-486 |
4.50e-90 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 288.48 E-value: 4.50e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:TIGR02482 32 VYGIRRGYKGLINGK--IEPLESKNVSGIIHRGGTILGTARCPEFKTEEVREKAVENLKKLGIEGLVVIGGDGSYTGAQK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEwsslldelvknktitteqqekfNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:TIGR02482 110 LYEE----------------------GGIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHERAFVIEV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQadwPDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHpitaeDVKKVIDERL 423
Cdd:TIGR02482 168 MGRHAGDLALYAGIATGAEIIIIPEFDYD---IDELIQRLKEQHEAGKKHSIIIVAEGNIVGSAK-----EVAKKIEEKT 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVISLDGNQAVRVPLME 486
Cdd:TIGR02482 240 GIETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGG---VMIGIQNNKIVTHPIEE 299
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
184-498 |
3.99e-84 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 273.13 E-value: 3.99e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGdcIQEANWASVSSIIHRGGTIIGSARCQDFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:cd00763 33 VYGIRDGYAGLIAGD--IVPLDRYSVSDIINRGGTFLGSARFPEFKDEEGQAKAIEQLKKHGIDALVVIGGDGSYMGAMR 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FrqewsslldelvknktitTEqqEKFNVlhiVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIMEV 343
Cdd:cd00763 111 L------------------TE--HGFPC---VGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQRISVVEV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 344 MGRHCGYLSVVAGIISEADYVFLPESPPQadwPDRLVLKLEQERSAGQRLNIVIVAEGAMDreghpitAEDVKKVIDERL 423
Cdd:cd00763 168 MGRHCGDIALAAGIAGGAEFIVIPEAEFD---REEVANRIKAGIERGKKHAIVVVAEGVYD-------VDELAKEIEEAT 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442623120 424 KHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVISLDGNQAVRVPLMECVERTQAVAKAM 498
Cdd:cd00763 238 GFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGG---LAVGIQNEQLVHHDIIDAIENMKPFKKDW 309
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
184-488 |
2.18e-66 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 225.26 E-value: 2.18e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGgDCIQEANWASVSSIIHRGGTIIGSARCQDFR-ERQGRLKAANNLIQRGITNLVVIGGDGSLTGAN 262
Cdd:TIGR02483 33 VIGIRDGWRGLLEG-DTVPLLDLEDVRGILPRGGTILGSSRTNPFKyEEDGDDKIVANLKELGLDALIAIGGDGTLGIAR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 263 LFRQewsslldelvknktitteqqekfNVLHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTFIME 342
Cdd:TIGR02483 112 RLAD-----------------------KGLPVVGVPKTIDNDLEATDYTFGFDTAVEIATEALDRLHTTAESHHRVMVVE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 343 VMGRHCGYLSVVAGIISEADYVFLPESPPqaDWpDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPITAEDVKKV---- 418
Cdd:TIGR02483 169 VMGRHAGWIALHSGIAGGADVILIPEIPF--DI-DSVCEKVRERFARGKRFAIVVVAEGAKPKGGEMVVQEGVKDAfghv 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 419 ------------IDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDsvpVVISLDGNQAVRVPLME 486
Cdd:TIGR02483 246 rlggignwlaeeIERRTGIETRATVLGHLQRGGSPSAFDRVLATRFGVAAVDLVHEGQFG---HMVALRGTDIVYVPIAE 322
|
..
gi 442623120 487 CV 488
Cdd:TIGR02483 323 AV 324
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
545-832 |
3.59e-58 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 203.00 E-value: 3.59e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTLP---EGKF 621
Cdd:COG0205 3 RIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPfktEEGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 622 KEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQ 701
Cdd:COG0205 83 EKALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG------IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 702 SAQGTkRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVYHMASK--------MAEGVSRGLIlrnEK 773
Cdd:COG0205 157 TAASH-ERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRgkgysiivVAEGAGDEDG---EA 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442623120 774 ASENYSTDFIYRLYSEEGKGL---------FTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAA 832
Cdd:COG0205 233 VLEADTDAFGHVRLGGIGEYLakeieertgIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLE 300
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
545-830 |
6.42e-57 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 199.45 E-value: 6.42e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRT----LPEGk 620
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCkefrTEEG- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 621 FKEIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDNYPQFcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 700
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPSKYQG-FNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 701 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQdvyhMASKMAEGVSRG----LILRNEKAse 776
Cdd:cd00363 160 DTAS-SHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADEWEEE----MVDVIKKRRERGkrhgIVIVAEGA-- 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442623120 777 nysTDFIYRLYSEEG-------KGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWL 830
Cdd:cd00363 233 ---IDFIPKPITEKLlaklveeRLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELL 290
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
545-831 |
2.00e-55 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 194.53 E-value: 2.00e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRTlPEGKFKEI 624
Cdd:PRK03202 3 RIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARF-PEFKDEEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 625 AAR----LKEFKIQGLLIIGGFESYHAAGQIADQRdnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 700
Cdd:PRK03202 82 RAKaienLKKLGIDALVVIGGDGSYMGAKRLTEHG-------IPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 701 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLqqdvyhmASKMAEGVSRG----LILRNEKA-S 775
Cdd:PRK03202 155 DTAS-SHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEEL-------CAKIKKGRERGkkhaIIVVAEGVmP 226
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 442623120 776 ENYSTDFIyrlyseEGKGLFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLA 831
Cdd:PRK03202 227 AEELAKEI------EERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLL 276
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
545-886 |
8.02e-54 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 189.93 E-value: 8.02e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRtLPEGKFKEI 624
Cdd:cd00763 2 RIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSAR-FPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 625 AAR----LKEFKIQGLLIIGGFESYHAAGQIADQRdnypqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIR 700
Cdd:cd00763 81 QAKaieqLKKHGIDALVVIGGDGSYMGAMRLTEHG-------FPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 701 QSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLQQDVyhmASKMAEGVSRGLILRNEKAsenYST 780
Cdd:cd00763 154 DTSS-SHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRI---KAGIERGKKHAIVVVAEGV---YDV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 781 DFIYRLYSEEGKglFTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAAqikaniDANGVVnckspdtatlLGIVSR 860
Cdd:cd00763 227 DELAKEIEEATG--FETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLA------GKGGLA----------VGIQNE 288
|
330 340
....*....|....*....|....*.
gi 442623120 861 QYRFSPLVDLIAEtnfdQRIPKKQWW 886
Cdd:cd00763 289 QLVHHDIIDAIEN----MKPFKKDWL 310
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
184-494 |
9.12e-40 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 150.99 E-value: 9.12e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARCQD---FRERQGRLKAANNLI-----QRGITNLVVIGGD 255
Cdd:PRK14071 38 VIGIRDATQGLMARPPQYIELDLDQVDDLLRMGGTILGTTNKGDpfaFPMPDGSLRDRSQEIidgyhSLGLDALIGIGGD 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 256 GSLtganlfrqewsSLLDELVknktitteQQEKFNvlhIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSH 335
Cdd:PRK14071 118 GSL-----------AILRRLA--------QQGGIN---LVGIPKTIDNDVGATEVSIGFDTAVNIATEALDRLHFTAASH 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 336 QRTFIMEVMGRHCGYLSVVAGIISEADYVFLPESPPQAdwpDRLVLKLEQERSAGQRLNIVIVAEGAMDREGHPITAED- 414
Cdd:PRK14071 176 NRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTL---ENVCKKIRERQEEGKNFCLVVVSEAVRTEEGEQVTKTQa 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 415 ------------VKKVIDERLKHDARITVLGHVQRGGNPSAFDRILACRMGAEATLALMEATKDSvpvVISLDGNQAVRV 482
Cdd:PRK14071 253 lgedryggigqyLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDR---MVAWQNRQVVSV 329
|
330
....*....|..
gi 442623120 483 PLMECVERTQAV 494
Cdd:PRK14071 330 PIAEAIATYRAV 341
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
545-874 |
3.03e-38 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 153.26 E-value: 3.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAG--NVRELGWSDVSGWVGQGGAYLGTKRTLpegKFK 622
Cdd:TIGR02478 2 RIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGgdNIEEAQWEDVRGILSLGGTIIGTARCK---EFR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 623 EIAARLKEFK------IQGLLIIGGFESYHAA-----------------GQI-ADQRDNYPQfcIPIVVIPSTISNNVPG 678
Cdd:TIGR02478 79 ERPGRLKAARnlvsngIDALVVIGGDGSLTGAdlfreewpslleelvdtGKItAEQAEEHRH--LTIVGLVGSIDNDMCG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 679 TEFSLGCDTGLNEITEICDRIRQSAQGTKrRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEkfSIKDLQQDvyHMASK 758
Cdd:TIGR02478 157 TDMTIGADSALHRICEAIDAISSTAQSHQ-RAFVVEVMGRHCGYLALMAAIATGADYVFIPER--PPEEGWED--QLCHK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 759 MAEGVSRG----LILRNEKASENYSTdfiyRLYSEEGKGLFT------CRMNILGHMQQGGSPTPFDRNMGTKMAAKCVD 828
Cdd:TIGR02478 232 LKRNRKAGkrktIVIVAEGAIDRDLN----PITSEDVKDVLVerlgldTRITVLGHVQRGGAPSAFDRILATRQGVEAVL 307
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 442623120 829 wlaAQIKANIDANGVVNCKSPDTATllgivsRQyrfsPLVDLIAET 874
Cdd:TIGR02478 308 ---AVLESTPETPSPVISLRGNKIV------RK----PLVEAVAQT 340
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
543-874 |
3.21e-36 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 147.28 E-value: 3.21e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 543 GYRLAVMHIGAPACGMNAAVRSFVRNAIYRGDVVYGINDGVEGLIAG--NVRELGWSDVSGWVGQGGAYLGTKR----TL 616
Cdd:cd00764 3 GKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGgdYIKQAEWESVSNWLQEGGTIIGSARckefRE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 617 PEGKfKEIAARLKEFKIQGLLIIGG-----------------FESYHAAGQIA-DQRDNYPQfcIPIVVIPSTISNNVPG 678
Cdd:cd00764 83 REGR-LQAAYNLIQRGITNLCVIGGdgsltgadlfrsewpslLEELVKDGKITeEEVAKYQH--LNIVGMVGSIDNDFCG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 679 TEFSLGCDTGLNEITEICDRIRQSAQgTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSikDLQQDvyHMASK 758
Cdd:cd00764 160 TDMTIGTDSALHRICEVVDAITTTAQ-SHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPE--DGWED--QMCRR 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 759 MAEGVSRGLILRNEKASENYSTDFIYRLYSEEGKGL------FTCRMNILGHMQQGGSPTPFDRNMGTKMAAKCVdwlaa 832
Cdd:cd00764 235 LSEHRSRGKRLNIIIVAEGAIDDQLKPITSEDVKDLvverlgLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAV----- 309
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 442623120 833 qiKANIDAngvvnckSPDT-ATLLGIVSRQYRFSPLVDLIAET 874
Cdd:cd00764 310 --MALLEA-------TPDTpACVVSLNGNKAVRLPLMECVQLT 343
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
542-832 |
3.11e-25 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 108.23 E-value: 3.11e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 542 EGYRLAVMHIGAPACGMNAAVRSFVRNAIYR-GDVVYGINDGVEGLIAG--NVRELGWSDVSGWVGQGGAYLGTKRT--- 615
Cdd:PRK14071 3 EKKRIGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNKgdp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 616 ----LPEGKFK----EIAARLKEFKIQGLLIIGGFESYHAAGQIADQRDnypqfcIPIVVIPSTISNNVPGTEFSLGCDT 687
Cdd:PRK14071 83 fafpMPDGSLRdrsqEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQGG------INLVGIPKTIDNDVGATEVSIGFDT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 688 GLNEITEICDRIRQSAqGTKRRVFVIETMGGYCGYLATLAGLAGGADAAYIYEEKFSIKDLqqdVYHMASKMAEGVSRGL 767
Cdd:PRK14071 157 AVNIATEALDRLHFTA-ASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENV---CKKIRERQEEGKNFCL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 768 ILRNE--KASENYSTDFIYRL----------YSEEGKGLFT---CRMNILGHMQQGGSPTPFDRNMGTKMAAKCVDWLAA 832
Cdd:PRK14071 233 VVVSEavRTEEGEQVTKTQALgedryggigqYLAEQIAERTgaeTRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQ 312
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
184-519 |
6.81e-25 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 108.98 E-value: 6.81e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMVdggdciqEANW-----ASVSSIIHRGGTIIGSARCQDFRErqgrlKAANNLIQRGITNLVVIGGDGSL 258
Cdd:PTZ00286 122 IYGAKYGYKGLY-------KEDWikldpKDVKTIHRLGGTILGSSRGGFDPK-----VMVDTLIRHGINILFTLGGDGTH 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 259 TGANlfrqewsSLLDELVKNK-TITteqqekfnvlhIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQR 337
Cdd:PTZ00286 190 RGAL-------AIYKELRRRKlNIS-----------VVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAYVEAKSAKN 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 338 TF-IMEVMGRHCGYLSVVAGIIS-EADYVFLPESppqaDWPDRLVLKLEQERSAGQRLNIVIVAEGAMD--REGHPITAE 413
Cdd:PTZ00286 252 GVgIVKLMGRDSGFIALHASVASaDVNVCLIPEF----DIPLEGVLEYIEQRLQKKGHCVIVVAEGAGQslKDADLDLGT 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 414 D-------------VKKVIDERLKHDARITVLGHVQ-----RGGNPSAFDRILACRMgaeATLALMEATKDSVPVVISLD 475
Cdd:PTZ00286 328 DasgnkklwdigvyLKDEITKYLKKKKPEHTVKYIDpsymiRAVPANAADAKFCTQL---AQNAVHGAMAGFTGFIIGHV 404
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 442623120 476 GNQAVRVPLmecvertqavaKAMAEKrWADAVKLRGRSFERNLE 519
Cdd:PTZ00286 405 HNNYVMIPI-----------KEMSGN-YRRRVNPEGRLWQRMLA 436
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
184-402 |
5.78e-19 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 90.70 E-value: 5.78e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 184 VYFIREGYQGMV-DGGDCIQEANWASVSSIIHRGGTIIGSAR-CQDFRErqgrlkAANNLIQRGITNLVVIGGDGSLTGA 261
Cdd:PRK06830 115 ILGIRYGYQGLIpRYGHDPVELTPEVVADIHEFGGTILGSSRgPQDPEE------IVDTLERMNINILFVIGGDGTLRGA 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 262 NLFRQEwsslldelvknktiTTEQQEKFNVlhiVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYSHQRTF-I 340
Cdd:PRK06830 189 SAIAEE--------------IERRGLKISV---IGIPKTIDNDINFIQKSFGFETAVEKATEAIRCAHVEANGAPNGIgL 251
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442623120 341 MEVMGRHCGYLSVVAGIIS-EADYVFLPESPPQADWPDRLVLKLEqERSAGQRLNIVIVAEGA 402
Cdd:PRK06830 252 VKLMGRHSGFIAAYAALASkDVNFVLIPEVPFDLEGPNGLLAALE-KRLAERGHAVIVVAEGA 313
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
208-402 |
3.55e-13 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 72.86 E-value: 3.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 208 SVSSIIHRGGTIIGSARC-QDFRerqgrlKAANNLIQRGITNLVVIGGDGSLTGANLFRQEWsslldelvknktitteQQ 286
Cdd:PLN02564 144 VVNDIHKRGGTILGTSRGgHDTS------KIVDSIQDRGINQVYIIGGDGTQKGASVIYEEI----------------RR 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 287 EKFNVLhIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAISSTAYS-HQRTFIMEVMGRHCGYLSVVAGIIS-EADYV 364
Cdd:PLN02564 202 RGLKVA-VAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESvENGIGLVKLMGRYSGFIAMYATLASrDVDCC 280
|
170 180 190
....*....|....*....|....*....|....*...
gi 442623120 365 FLPESPPQADWPDRLVLKLEQERSAGQRLNIViVAEGA 402
Cdd:PLN02564 281 LIPESPFYLEGKGGLFEFIEKRLKENGHMVIV-VAEGA 317
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
557-724 |
7.14e-13 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 72.00 E-value: 7.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 557 GMNAAVRSFVRNAIYRGDV--VYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKRtlpeGKF--KEIAARLKEFK 632
Cdd:PTZ00286 101 GLNVVIRELVMNLINNYGVktIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSR----GGFdpKVMVDTLIRHG 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 633 IQGLLIIGGFESYHAAGQIADQ--RDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKRRV 710
Cdd:PTZ00286 177 INILFTLGGDGTHRGALAIYKElrRRKLN---ISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAYVEAKSAKNGV 253
|
170
....*....|....
gi 442623120 711 FVIETMGGYCGYLA 724
Cdd:PTZ00286 254 GIVKLMGRDSGFIA 267
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
187-456 |
2.61e-11 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 66.76 E-value: 2.61e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 187 IREGYQGMVDGGDCIQEANWASVSSIIHRGGTIIGSARcqdfrerqGRLKAA---NNLIQRGITNLVVIGGDGSLTGANL 263
Cdd:PLN02884 90 IPFGYRGFFEKGLSEMPLSRKVVQNIHLSGGSLLGVSR--------GGAKTSdivDSIEARGINMLFVLGGNGTHAGANA 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 FRQEWsslldelvknktitteQQEKFNVLhIVGLVGSIDNDFCGTDMTIGTDTALHriiEAIDAISStAYSHQRTF---- 339
Cdd:PLN02884 162 IHNEC----------------RKRKMKVS-VVGVPKTIDNDILLMDKTFGFDTAVE---EAQRAINS-AYIEAHSAyhgi 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 340 -IMEVMGRHCGYLSVVAGIIS-EADYVFLPESPPQADWPDRLVLKL----EQERSAgqrlnIVIVAEGA----------M 403
Cdd:PLN02884 221 gLVKLMGRSSGFIAMHASLASgQVDICLIPEVPFTLDGPNGVLRHLehliETKGSA-----VVCVAEGAgqdllqktnaT 295
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442623120 404 DREGHPITAEDVKKVIDERLKHDARITVLGHVQ--------RGGNPSAFDRILACRMGAEA 456
Cdd:PLN02884 296 DASGNPVLGDIGVHLQQEIKKHFKDIGVPADVKyidptymiRACRANASDAILCTVLGQNA 356
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
292-472 |
2.20e-10 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 63.73 E-value: 2.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 292 LHIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAI--DAISSTAY-SHQRTFIMEVMGRHCGYLSVVAGIISE-----ADY 363
Cdd:PRK14072 133 IRCIGIPKTIDNDLPGTDHCPGFGSAAKYIATSVleAALDVAAMaNTSKVFILEVMGRHAGWLAAAAALAKQnpddaPHL 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 364 VFLPESP-PQADWpdrlvlkLEQERSAGQRLN--IVIVAEGAMDREGHPI----TAED-------------VKKVIDERL 423
Cdd:PRK14072 213 IYLPERPfDEEKF-------LADVRAIVKRYGycVVVVSEGIRDADGKFIaeagLAEDafghaqlggvapvLANLIKEKL 285
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 442623120 424 KHDARITVLGHVQR--GGNPSAFDRILACRMGAEATLALMeATKDSVPVVI 472
Cdd:PRK14072 286 GKKVHWAVLDYLQRaaRHIASKTDVEEAYAVGKAAVEYAL-AGKNGVMPAI 335
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
188-458 |
2.65e-10 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 63.49 E-value: 2.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 188 REGYQGMVdGGDCIQ-----EANwasvSSIIHR-GGTIIGSAR--------CQD---FRERQGRLK-AANNLIQRGITNL 249
Cdd:PRK06555 42 RSGYQGLL-LGDSIEitpavRAN----AGLLHRyGGSPIGNSRvkltnvadCVKrglVKEGENPLKvAAERLAADGVDIL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 250 VVIGGDGSLTGAnlfrqewSSLLDELVKNKTITTeqqekfnvlhIVGLVGSIDNDFCGTDMTIGTDTALHRIIEAIDAIS 329
Cdd:PRK06555 117 HTIGGDDTNTTA-------ADLAAYLAENGYDLT----------VVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVI 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 330 STAYSHQRTFIM-EVMGRHCGYLSV---------------VAGIISEA-----DYVFLPEsppqadwpdrLVLKLEQErs 388
Cdd:PRK06555 180 NEHSANPRMLIIhEVMGRNCGWLTAatarayrewldrqeyVPGFGLSAerwdiHAVYLPE----------MAFDLEAE-- 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 389 aGQRLNIVivaegaMDREG------------HPITAEDVKKviDERLKHDAritvLGHVQRGG-NPSA-FDRILACRMGA 454
Cdd:PRK06555 248 -AERLKAV------MDEVGnvniflsegaglDAIVAEMEAA--GEEVKRDA----FGHVKLDTiNPGAwFAKQFAELLGA 314
|
....
gi 442623120 455 EATL 458
Cdd:PRK06555 315 EKVM 318
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
557-725 |
9.70e-07 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 52.18 E-value: 9.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 557 GMNAAVRSFVRNAIYRGDV--VYGINDGVEGLIAG---NVRELGWSDVSGWVGQGGAYLGTKR--TLPEgkfkEIAARLK 629
Cdd:PRK06830 94 GLNDVIRAIVLELHHHYGVrrILGIRYGYQGLIPRyghDPVELTPEVVADIHEFGGTILGSSRgpQDPE----EIVDTLE 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 630 EFKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTK 707
Cdd:PRK06830 170 RMNINILFVIGGDGTLRGASAIAEeiERRGLK---ISVIGIPKTIDNDINFIQKSFGFETAVEKATEAIRCAHVEANGAP 246
|
170
....*....|....*...
gi 442623120 708 RRVFVIETMGGYCGYLAT 725
Cdd:PRK06830 247 NGIGLVKLMGRHSGFIAA 264
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
557-724 |
8.91e-06 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 49.36 E-value: 8.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 557 GMNAAVRSFV--RNAIYRGDVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGGAYLGTKR----TlpegkfKEIAARLKE 630
Cdd:PLN02564 101 GLNTVIREIVcgLSYMYGVTRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTSRgghdT------SKIVDSIQD 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 631 FKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGTEFSLGCDTGLNEITEICDRIRQSAQGTKR 708
Cdd:PLN02564 175 RGINQVYIIGGDGTQKGASVIYEeiRRRGLK---VAVAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESVEN 251
|
170
....*....|....*.
gi 442623120 709 RVFVIETMGGYCGYLA 724
Cdd:PLN02564 252 GIGLVKLMGRYSGFIA 267
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
209-404 |
2.02e-04 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 45.35 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 209 VSSIIHRGG-TIIGSARCQDFRERQgrLKAANNLIQR-GITNLVVIGGDGSLTGANL----FRQEWSSLLdelvknktit 282
Cdd:PTZ00468 160 INGILNQGGfNIICSGRHKIETEEQ--MRASLEICEKlKLHGLVVIGGDDSNTNAAVlaeyFKRNSSSTV---------- 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 283 teqqekfnvlhIVGLVGSIDNDFCG--TDMTIGTDTALHRIIEAIDAI-SSTAYSHQRTFIMEVMGRHCGYLSVVAGIIS 359
Cdd:PTZ00468 228 -----------VVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQIGSImDAIKTEGYGYYFVRLMGRSASHITLECGLQT 296
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 442623120 360 EADYVFLPESPPQADWP-----DRLVLKLEQERSAGQRLNIVIVAEGAMD 404
Cdd:PTZ00468 297 RANMILIGEEIKEENRSlmsivDEIVEMILKRDSLGKKHGIVLLPEGLIE 346
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
545-717 |
6.24e-04 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 43.37 E-value: 6.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 545 RLAVMHIGAPA-------CGMNAAVRSFVRNAiyrgdVVYGINDGVEGLIAGNVRELGWSDVSGWVGQGG-AYLGTKRTL 616
Cdd:PRK07085 72 KVGVILSGGQApgghnviAGLFDGLKKLNPDS-----KLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGRTK 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 617 PEGK--FKEIAARLKEFKIQGLLIIGGFESYHAAGQIAD--QRDNYPqfcIPIVVIPSTISNNVPGT--EFSLGCDTGLN 690
Cdd:PRK07085 147 IETEeqKEACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfAKHGCK---TQVIGVPKTIDGDLKNEfiETSFGFDTATK 223
|
170 180
....*....|....*....|....*..
gi 442623120 691 EITEICDRIRQSAQGTKRRVFVIETMG 717
Cdd:PRK07085 224 TYSEMIGNISRDALSAKKYWHFIKLMG 250
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
190-404 |
9.36e-04 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 43.10 E-value: 9.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 190 GYQGMVDGgdcIQEANWASVS-SIIHR-----GGTIIGSARCQdFRERQGRLKAANNLIQRGITNLVVIGGDGSLTGAnl 263
Cdd:PTZ00287 214 GFLGGIDG---LYSKNYVTITdSLMNRfrnlgGFNMLWSGRGK-VRNKDDLIAIENIVAKLKLNGLVIIGGDGSNSNA-- 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 264 frqewsSLLDELVKNKTITteqqekfnvLHIVGLVGSIDNDFC--GTDMTIGTDTALHRIIEAIDAISSTAYS-HQRTFI 340
Cdd:PTZ00287 288 ------ALISEYFAERQIP---------ISIIGIPKTIDGDLKseAIEISFGFDTATKTYSEVIGNLCTDVKTgHNVYHV 352
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442623120 341 MEVMGRHCGYLSVVAGIISEADYVFLPESPPQ-----ADWPDRLVLKLEQERSAGQRLNIVIVAEGAMD 404
Cdd:PTZ00287 353 VRVMGRSASHVVLECALQTRPNIVLIGEEVEKenlslKDIVSNIVNTILKRRSLNKNYGVILIPEGLIE 421
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
216-404 |
5.11e-03 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 40.62 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 216 GGTIIGSARCQDFRERQGRlKAANNLIQRGITNLVVIGGDGSLTGAnlfrqewsSLLDELVKNKTITTEqqekfnvlhIV 295
Cdd:cd00765 138 GFDMICSGRTKIETEDQFK-QAEETAKKLDLDALVVIGGDDSNTNA--------ALLAENFRSKGLKTR---------VI 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623120 296 GLVGSIDNDFCGTDMTI--GTDTALHRIIE-----AIDAISSTAYSHqrtFImEVMGRHCGYLSVVAG--------IISE 360
Cdd:cd00765 200 GVPKTIDGDLKNKEIETsfGFDTATKIYSElignvMRDARSTGKYWH---FV-KLMGRSASHIALECAlkthpnicIISE 275
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 442623120 361 AdyvFLPESPPQADWPDRLVLKLEQERSAGQRLNIVIVAEGAMD 404
Cdd:cd00765 276 E---VSAQKQTLKNITDYMVDVICKRAELGYNFGVVLVPEGLIE 316
|
|
| |
