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Conserved domains on  [gi|442623664|ref|NP_001260966|]
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uncharacterized protein Dmel_CG18327, isoform B [Drosophila melanogaster]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 5-293 7.74e-22

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 92.91  E-value: 7.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664   5 DFVLGGVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQP-YKSVFQAFVTVAKNDGILGLQKG-------LAPALCFQ 76
Cdd:PTZ00169  10 DFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPrYSGIVNCFRRVSKEQGVLSLWRGntanvirYFPTQAFN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  77 FVINSFRLSIYTHavekgwvHNNKGEIS--FAKGMFWGALGGVVGSYCASPFFLIKTQLqaqaAKQIAVGYQHQHASMSD 154
Cdd:PTZ00169  90 FAFKDYFKNMFPK-------YNQKTDFWkfFGVNILSGGLAGASSLLIVYPLDFARTRL----ASDIGKGGDREFTGLFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664 155 AIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLL---KENGVVTHPTILSFCSGLAAGsfvsLAITPLDVV 231
Cdd:PTZ00169 159 CLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfgnDKNTNILYKWAVAQTVTILAG----LISYPFDTV 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442623664 232 TTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPySTLVLLFFDEL 293
Cdd:PTZ00169 235 RRRMMMMSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAG-GALVLVFYDEL 295
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 5-293 7.74e-22

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 92.91  E-value: 7.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664   5 DFVLGGVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQP-YKSVFQAFVTVAKNDGILGLQKG-------LAPALCFQ 76
Cdd:PTZ00169  10 DFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPrYSGIVNCFRRVSKEQGVLSLWRGntanvirYFPTQAFN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  77 FVINSFRLSIYTHavekgwvHNNKGEIS--FAKGMFWGALGGVVGSYCASPFFLIKTQLqaqaAKQIAVGYQHQHASMSD 154
Cdd:PTZ00169  90 FAFKDYFKNMFPK-------YNQKTDFWkfFGVNILSGGLAGASSLLIVYPLDFARTRL----ASDIGKGGDREFTGLFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664 155 AIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLL---KENGVVTHPTILSFCSGLAAGsfvsLAITPLDVV 231
Cdd:PTZ00169 159 CLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfgnDKNTNILYKWAVAQTVTILAG----LISYPFDTV 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442623664 232 TTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPySTLVLLFFDEL 293
Cdd:PTZ00169 235 RRRMMMMSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAG-GALVLVFYDEL 295
Mito_carr pfam00153
Mitochondrial carrier protein;
204-293 1.10e-18

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 79.24  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  204 THPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRgiyYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPYS 283
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|
gi 442623664  284 TLVLLFFDEL 293
Cdd:pfam00153  79 AIYFGTYETL 88
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 5-293 7.74e-22

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 92.91  E-value: 7.74e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664   5 DFVLGGVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQP-YKSVFQAFVTVAKNDGILGLQKG-------LAPALCFQ 76
Cdd:PTZ00169  10 DFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKVPrYSGIVNCFRRVSKEQGVLSLWRGntanvirYFPTQAFN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  77 FVINSFRLSIYTHavekgwvHNNKGEIS--FAKGMFWGALGGVVGSYCASPFFLIKTQLqaqaAKQIAVGYQHQHASMSD 154
Cdd:PTZ00169  90 FAFKDYFKNMFPK-------YNQKTDFWkfFGVNILSGGLAGASSLLIVYPLDFARTRL----ASDIGKGGDREFTGLFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664 155 AIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLL---KENGVVTHPTILSFCSGLAAGsfvsLAITPLDVV 231
Cdd:PTZ00169 159 CLMKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfgnDKNTNILYKWAVAQTVTILAG----LISYPFDTV 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442623664 232 TTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPySTLVLLFFDEL 293
Cdd:PTZ00169 235 RRRMMMMSGRKAKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAG-GALVLVFYDEL 295
Mito_carr pfam00153
Mitochondrial carrier protein;
204-293 1.10e-18

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 79.24  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  204 THPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRgiyYRGWLDCVLTILRSEGVYGLYKGFWPIYLRSAPYS 283
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|
gi 442623664  284 TLVLLFFDEL 293
Cdd:pfam00153  79 AIYFGTYETL 88
Mito_carr pfam00153
Mitochondrial carrier protein;
101-201 2.43e-18

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 78.47  E-value: 2.43e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664  101 GEISFAKGMFWGALGGVVGSYCASPFFLIKTQLQAQAAKqiavgYQHQHASMSDAIRKIYRKNGVFGLWRGSLANVSRAT 180
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGS-----GKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVA 75

                          90       100
                  ....*....|....*....|.
gi 442623664  181 VASAVQIAVFGQAKSLLKENG 201
Cdd:pfam00153  76 PAAAIYFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
4-87 4.35e-14

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 66.91  E-value: 4.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442623664    4 SDFVLGGVAAMGAGVFTNPVEVIKTRIQLQGelaarGSHAQPYKSVFQAFVTVAKNDGILGLQKGLAPALCFQFVINSFR 83
Cdd:pfam00153   7 ASLLAGGIAGAIAVTVTYPLDVVKTRLQVQG-----GSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIY 81


                  ....
gi 442623664   84 LSIY 87
Cdd:pfam00153  82 FGTY 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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