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Conserved domains on  [gi|442634135|ref|NP_001262206|]
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cysteine string protein, isoform D [Drosophila melanogaster]

Protein Classification

J domain-containing protein( domain architecture ID 10446266)

J domain-containing protein containing a similar domain as DnaJ, a protein that plays crucial roles in protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of Hsp70.

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  35729039|9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 17-79 2.30e-34

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 117.57  E-value: 2.30e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135   17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYD 79
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 17-79 2.30e-34

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 117.57  E-value: 2.30e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135   17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYD 79
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 19-91 2.80e-31

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 112.49  E-value: 2.80e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQ 91
Cdd:COG0484    3 YEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAELLLAT 75
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 19-82 3.43e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 117.94  E-value: 3.43e-31
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK10767   7 YEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYG 70
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 19-86 4.97e-29

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 111.92  E-value: 4.97e-29
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135   19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDnVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD-KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGF 69
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 19-71 6.98e-27

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.39  E-value: 6.98e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSD 71
Cdd:cd06257    3 YDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
DnaJ smart00271
DnaJ molecular chaperone homology domain;
17-74 2.66e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 96.92  E-value: 2.66e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 442634135    17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDN-VDAADKFKEVNRAHSILSDQTK 74
Cdd:smart00271   2 DYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDkEEAEEKFKEINEAYEVLSDPEK 60
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
19-86 1.18e-21

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 92.58  E-value: 1.18e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAP-DAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV 74
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 17-79 2.30e-34

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 117.57  E-value: 2.30e-34
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135   17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYD 79
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPEAEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 19-91 2.80e-31

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 112.49  E-value: 2.80e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQ 91
Cdd:COG0484    3 YEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPEAEEKFKEINEAYEVLSDPEKRAAYDRFGHAAELLLAT 75
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 19-82 3.43e-31

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 117.94  E-value: 3.43e-31
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK10767   7 YEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKEAEEKFKEIKEAYEVLSDPQKRAAYDQYG 70
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 19-86 4.97e-29

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 111.92  E-value: 4.97e-29
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135   19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDnVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:TIGR02349   3 YEILGVSKDASEEEIKKAYRKLAKKYHPDRNKD-KEAEEKFKEINEAYEVLSDPEKRAQYDQFGHAGF 69
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 19-75 1.82e-27

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 100.07  E-value: 1.82e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKR 75
Cdd:COG5407    3 YEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDPKAEERFKEINEAYELLSDAEKR 59
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 19-71 6.98e-27

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 98.39  E-value: 6.98e-27
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSD 71
Cdd:cd06257    3 YDILGVPPDASDEEIKKAYRKLALKYHPDKNPDDPEAEEKFKEINEAYEVLSD 55
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 11-97 1.54e-26

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 105.70  E-value: 1.54e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634135  11 LSTSGDsLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDnVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGlyIAE 90
Cdd:PRK14298   1 MATTRD-YYEILGLSKDASVEDIKKAYRKLAMKYHPDKNKE-PDAEEKFKEISEAYAVLSDAEKRAQYDRFGHAG--IDN 76


                 ....*..
gi 442634135  91 QFGEENV 97
Cdd:PRK14298  77 QYSAEDI 83
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 19-86 1.61e-26

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 105.66  E-value: 1.61e-26
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14281   6 YEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKEAEEHFKEVNEAYEVLSNDDKRRRYDQFGHAGV 73
DnaJ smart00271
DnaJ molecular chaperone homology domain;
17-74 2.66e-26

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 96.92  E-value: 2.66e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 442634135    17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDN-VDAADKFKEVNRAHSILSDQTK 74
Cdd:smart00271   2 DYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDkEEAEEKFKEINEAYEVLSDPEK 60
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 19-86 2.74e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 102.15  E-value: 2.74e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14294   7 YEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDKEAEELFKEAAEAYEVLSDPKKRGIYDQYGHEGL 74
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 19-95 3.81e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 99.07  E-value: 3.81e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPdNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIA--EQFGEE 95
Cdd:PRK14291   6 YEILGVSRNATQEEIKKAYRRLARKYHPDFNK-NPEAEEKFKEINEAYQVLSDPEKRKLYDQFGHAAFSGSgqQQQGQE 83
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 18-82 1.37e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 97.56  E-value: 1.37e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442634135  18 LYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK14277   7 YYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKEAEQKFKEINEAYEILSDPQKRAQYDQFG 71
PRK14297 PRK14297
molecular chaperone DnaJ;
19-83 1.74e-23

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 97.16  E-value: 1.74e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGS 83
Cdd:PRK14297   7 YEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKEAEEKFKEINEAYQVLSDPQKKAQYDQFGT 71
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 19-87 1.81e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 97.22  E-value: 1.81e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLY 87
Cdd:PRK14284   4 YTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAEAEKRFKEVSEAYEVLSDAQKRESYDRYGKDGPF 72
PRK14289 PRK14289
molecular chaperone DnaJ;
19-86 1.59e-22

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 94.51  E-value: 1.59e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14289   8 YEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKEAEEKFKEAAEAYDVLSDPDKRSRYDQFGHAGV 75
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
19-86 1.18e-21

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 92.58  E-value: 1.18e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:NF037946   8 YEVLGVDRDADDQEIKKAFRKLAKKYHPDRNKAP-DAAEIFAEINEAYEVLSNPEKRANYDKYGHDGV 74
PRK14295 PRK14295
molecular chaperone DnaJ;
19-84 1.28e-21

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 92.22  E-value: 1.28e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSL 84
Cdd:PRK14295  12 YKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDAKAEERFKEISEAYDVLSDEKKRKEYDEARSL 77
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 1-86 1.36e-21

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 92.58  E-value: 1.36e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634135   1 MSAPGMD--KRKLSTSGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDnvdaADKFKEVNRAHSILSDQTKRNIY 78
Cdd:PTZ00037  11 MPGGGFDggRRKREVDNEKLYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKGGD----PEKFKEISRAYEVLSDPEKRKIY 86


                 ....*...
gi 442634135  79 DNYGSLGL 86
Cdd:PTZ00037  87 DEYGEEGL 94
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 19-86 3.93e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 90.57  E-value: 3.93e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14301   7 YEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPEAEQKFKEAAEAYEVLRDAEKRARYDRFGHAGV 74
PRK14280 PRK14280
molecular chaperone DnaJ;
19-85 4.05e-21

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 90.55  E-value: 4.05e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLG 85
Cdd:PRK14280   7 YEVLGVSKSASKDEIKKAYRKLSKKYHPDINKEE-GADEKFKEISEAYEVLSDDQKRAQYDQFGHAG 72
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 14-86 1.47e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 88.89  E-value: 1.47e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 442634135  14 SGDSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14286   2 SERSYYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKESEEKFKEATEAYEILRDPKKRQAYDQFGKAGV 74
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 6-98 2.36e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 88.34  E-value: 2.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634135   6 MDKRklstsgdSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLG 85
Cdd:PRK14283   2 AEKR-------DYYEVLGVDRNADKKEIKKAYRKLARKYHPDVSEEE-GAEEKFKEISEAYAVLSDDEKRQRYDQFGHAG 73

                         90
                 ....*....|....*..
gi 442634135  86 LyiaEQFGEE----NVN 98
Cdd:PRK14283  74 M---DGFSQEdifnNIN 87
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 18-85 2.85e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 88.22  E-value: 2.85e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  18 LYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLG 85
Cdd:PRK14276   6 YYDRLGVSKDASQDEIKKAYRKLSKKYHPDINKEP-GAEEKYKEVQEAYETLSDPQKRAAYDQYGAAG 72
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 19-82 3.42e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 88.12  E-value: 3.42e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK14285   6 YEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKEAESIFKEATEAYEVLIDDNKRAQYDRFG 69
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 19-83 3.59e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 86.92  E-value: 3.59e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGS 83
Cdd:PRK14299   7 YAILGVPKNASQDEIKKAFKKLARKYHPDVNKSP-GAEEKFKEINEAYTVLSDPEKRRIYDTYGT 70
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 19-83 4.18e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 87.64  E-value: 4.18e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGS 83
Cdd:PRK14292   5 YELLGVSRTASADEIKSAYRKLALKYHPDRNKEK-GAAEKFAQINEAYAVLSDAEKRAHYDRFGT 68
PRK14293 PRK14293
molecular chaperone DnaJ;
19-86 1.10e-19

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 86.58  E-value: 1.10e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDnVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14293   6 YEILGVSRDADKDELKRAYRRLARKYHPDVNKE-PGAEDRFKEINRAYEVLSDPETRARYDQFGEAGV 72
PRK14279 PRK14279
molecular chaperone DnaJ;
19-84 9.91e-19

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 84.01  E-value: 9.91e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSL 84
Cdd:PRK14279  12 YKELGVSSDASAEEIKKAYRKLARELHPDANPGDPAAEERFKAVSEAHDVLSDPAKRKEYDETRRL 77
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 19-79 1.22e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 83.56  E-value: 1.22e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYD 79
Cdd:PRK14278   6 YGLLGVSRNASDAEIKRAYRKLARELHPDVNPDE-EAQEKFKEISVAYEVLSDPEKRRIVD 65
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 19-85 3.35e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 82.53  E-value: 3.35e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDN-VDAADKFKEVNRAHSILSDQTKRNIYDNYGSLG 85
Cdd:PRK14282   7 YEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENrKEAEQKFKEIQEAYEVLSDPQKRAMYDRFGYVG 74
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 19-83 4.17e-18

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 82.29  E-value: 4.17e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDN-VDAADKFKEVNRAHSILSDQTKRNIYDNYGS 83
Cdd:PRK14290   6 YKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNkAEAEEKFKEISEAYEVLSDPQKRRQYDQTGT 71
PRK14288 PRK14288
molecular chaperone DnaJ;
17-86 5.58e-18

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 81.66  E-value: 5.58e-18
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 442634135  17 SLYEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PRK14288   4 SYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGL 73
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
16-79 9.14e-18

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 75.52  E-value: 9.14e-18
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 442634135  16 DSLYEILGLPKTATGDDIKKTYRKLALKYHPDKNP-DNVDAADKFKEVNRAHSILSDQTKRNIYD 79
Cdd:COG2214    5 KDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGeLKALAEELFQRLNEAYEVLSDPERRAEYD 69
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 19-82 1.17e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 78.06  E-value: 1.17e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK14296   7 YEVLGVSKTASEQEIRQAYRKLAKQYHPDLNKSP-DAHDKMVEINEAADVLLDKDKRKQYDQFG 69
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 19-82 3.07e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 76.98  E-value: 3.07e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDkNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK14300   6 YQILGVSKTASQADLKKAYLKLAKQYHPD-TTDAKDAEKKFKEINAAYDVLKDEQKRAAYDRFG 68
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 19-82 4.57e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 73.50  E-value: 4.57e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYG 82
Cdd:PRK14287   7 YEVLGVDRNASVDEVKKAYRKLARKYHPDVNKAP-DAEDKFKEVKEAYDTLSDPQKKAHYDQFG 69
PRK10266 PRK10266
curved DNA-binding protein;
19-80 1.85e-11

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 62.53  E-value: 1.85e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDN 80
Cdd:PRK10266   7 YAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEP-DAEARFKEVAEAWEVLSDEQRRAEYDQ 67
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
19-71 5.30e-10

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 54.42  E-value: 5.30e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDK-----NPDNVDAA-DKFKEVNRAHSILSD 71
Cdd:COG1076    7 FELLGLPPDADDAELKRAYRKLQREHHPDRlaaglPEEEQRLAlQKAAAINEAYETLKD 65
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 19-86 2.88e-08

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 54.02  E-value: 2.88e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135   19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNvDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGL 86
Cdd:PTZ00341  576 YDILGVGVNADMKEISERYFKLAENYYPPKRSGN-EGFHKFKKINEAYQILGDIDKKKMYNKFGYDGI 642
PHA03102 PHA03102
Small T antigen; Reviewed
 18-64 1.85e-07

Small T antigen; Reviewed


Pssm-ID: 222986 [Multi-domain]  Cd Length: 153  Bit Score: 49.28  E-value: 1.85e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 442634135  18 LYEILGLPKTATGD--DIKKTYRKLALKYHPDKNPDNvdaaDKFKEVNR 64
Cdd:PHA03102   7 LMDLLGLPRSAWGNlpLMRKAYLRKCLEFHPDKGGDE----EKMKELNT 51
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 18-80 4.44e-07

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 50.03  E-value: 4.44e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 442634135  18 LYEILGLPK---TATGDDIKKTYRKLALKYHPDKNP--DNVDAADKFKEVNRAHSILSDQTKRNIYDN 80
Cdd:COG5269   45 LYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAagGNKGCDEFFKLIQKAREVLGDRKLRLQYDS 112
PHA02624 PHA02624
large T antigen; Provisional
 18-64 1.35e-06

large T antigen; Provisional


Pssm-ID: 222912 [Multi-domain]  Cd Length: 647  Bit Score: 48.83  E-value: 1.35e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 442634135  18 LYEILGLPKTATGD--DIKKTYRKLALKYHPDKNPDNvdaaDKFKEVNR 64
Cdd:PHA02624  13 LMDLLGLPMAAWGNlpLMRKAYLRKCKEYHPDKGGDE----EKMKRLNS 57
djlA PRK09430
co-chaperone DjlA;
12-48 5.38e-06

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 46.34  E-value: 5.38e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 442634135  12 STSGDSL---YEILGLPKTATGDDIKKTYRKLALKYHPDK 48
Cdd:PRK09430 193 AQRGPTLedaYKVLGVSESDDDQEIKRAYRKLMSEHHPDK 232
hscB PRK01356
co-chaperone HscB; Provisional
 19-78 1.33e-04

co-chaperone HscB; Provisional


Pssm-ID: 167217 [Multi-domain]  Cd Length: 166  Bit Score: 41.40  E-value: 1.33e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 442634135  19 YEILGLPKTATGD--DIKKTYRKLALKYHPDKnPDNVDAADKF----KEVNRAHSILSDQTKRNIY 78
Cdd:PRK01356   5 FQLLGLPQEYNIDlkILEKQYFAMQVKYHPDK-AKTLQEKEQNliiaSELNNAYSTLKDALKRAEY 69
PTZ00100 PTZ00100
DnaJ chaperone protein; Provisional
 19-69 1.19e-03

DnaJ chaperone protein; Provisional


Pssm-ID: 240265  Cd Length: 116  Bit Score: 37.52  E-value: 1.19e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 442634135  19 YEILGLPKTATGDDIKKTYRKLALKYHPDKNPDNVDAAdkfkEVNRAHSIL 69
Cdd:PTZ00100  68 YKILNISPTASKERIREAHKQLMLRNHPDNGGSTYIAS----KVNEAKDLL 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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