NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|665395261|ref|NP_001263016|]
View 

uncharacterized protein Dmel_CG5611, isoform C [Drosophila melanogaster]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 39-256 7.97e-82

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PRK08259:

Pssm-ID: 474030  Cd Length: 254  Bit Score: 248.27  E-value: 7.97e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeAEAQRGSLnf 118
Cdd:PRK08259   1 MSMSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV-GTGRGNRL-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK08259  78 HPSGDGPMGPSRMRLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENAN 256
Cdd:PRK08259 158 ILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAFPQTCLRADRLSALEQWG 215
 
Name Accession Description Interval E-value
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-256 7.97e-82

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 248.27  E-value: 7.97e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeAEAQRGSLnf 118
Cdd:PRK08259   1 MSMSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV-GTGRGNRL-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK08259  78 HPSGDGPMGPSRMRLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENAN 256
Cdd:PRK08259 158 ILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAFPQTCLRADRLSALEQWG 215
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 43-289 1.98e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.16  E-value: 1.98e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:COG1024   81 LQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENANAYNKPGFHVASYNEIMNVTSDmitDM 282
Cdd:COG1024  161 RRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASE---DA 237


                 ....*..
gi 665395261 283 QEGVKRF 289
Cdd:COG1024  238 REGIAAF 244
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 43-233 1.00e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 171.97  E-value: 1.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIAT 201
Cdd:cd06558   81 ELQELLRAlLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLT 160

                        170       180       190
                 ....*....|....*....|....*....|..
gi 665395261 202 GRRIYSGEARRIGLVNRVVATGTALGQAVNLA 233
Cdd:cd06558  161 GRRISAEEALELGLVDEVVPDEELLAAALELA 192
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 46-314 1.23e-32

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 121.31  E-value: 1.23e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261   46 EKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeaeaQRGSLNFLLRHEGS 125
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEM----YGEGPAHQALYREN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  126 VGPTRRHLR---KPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:pfam00378  77 VLDLWTLLYtcpKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMhdrnAVLENANAYNKPGFHVASYNEIMNVTSDMIT-D 281
Cdd:pfam00378 157 RRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALA----QLKKALNAKLEDALPTQLEAEARLFYSTFSKdD 232

                         250       260       270
                  ....*....|....*....|....*....|...
gi 665395261  282 MQEGVKRFknseikgpktdswsiKEKTIPDWEK 314
Cdd:pfam00378 233 IIEGLQAF---------------LEKRKPPWED 250
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 34-220 2.32e-20

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 91.82  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261   34 SQEGAP-ART-VLVEKDSHITLIGLNREQQR-NSIDANTAEQLTEAISQFEADDTSPVGVLY-GIGGSFCAGYDLEELEA 109
Cdd:TIGR02441   4 STSAALmARThRHYEVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLIsGKPGSFVAGADIQMIAA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  110 EaQRGSLNFLLRHEGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVM--EDTAVLGFFNRRLGVPLSDGGTVRL 186
Cdd:TIGR02441  84 C-KTAQEVTQLSQEGQEMFERiEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRL 162

                         170       180       190
                  ....*....|....*....|....*....|....
gi 665395261  187 AAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:TIGR02441 163 PKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLV 196
 
Name Accession Description Interval E-value
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
39-256 7.97e-82

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 248.27  E-value: 7.97e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeAEAQRGSLnf 118
Cdd:PRK08259   1 MSMSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV-GTGRGNRL-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK08259  78 HPSGDGPMGPSRMRLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENAN 256
Cdd:PRK08259 158 ILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAFPQTCLRADRLSALEQWG 215
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 43-289 1.98e-61

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 196.16  E-value: 1.98e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEARAFARG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:COG1024   81 LQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENANAYNKPGFHVASYNEIMNVTSDmitDM 282
Cdd:COG1024  161 RRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASE---DA 237


                 ....*..
gi 665395261 283 QEGVKRF 289
Cdd:COG1024  238 REGIAAF 244
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 43-233 1.00e-52

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 171.97  E-value: 1.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEEARAFIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIAT 201
Cdd:cd06558   81 ELQELLRAlLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLT 160

                        170       180       190
                 ....*....|....*....|....*....|..
gi 665395261 202 GRRIYSGEARRIGLVNRVVATGTALGQAVNLA 233
Cdd:cd06558  161 GRRISAEEALELGLVDEVVPDEELLAAALELA 192
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
39-237 2.10e-44

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 152.45  E-value: 2.10e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEeleaEAQRGSlNF 118
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLK----AFARGE-RP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK08252  76 SIPGRGFGGLTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMEL 155

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA 237
Cdd:PRK08252 156 ALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIA 194
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
43-257 4.88e-39

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 138.56  E-value: 4.88e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFllrH 122
Cdd:PRK06563   1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVAPKLAAGGFPF---P 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTR---RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEII 199
Cdd:PRK06563  78 EGGIDPWGtvgRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 665395261 200 ATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFP----MASLMHDRNAVLENANA 257
Cdd:PRK06563 158 LTGDEFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAAplgvQATLASARAAVREGEAA 219
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
44-313 4.90e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 136.00  E-value: 4.90e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  44 LVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNfllrhE 123
Cdd:PRK07799   8 LVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKPPGDSFK-----D 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 124 GSVGPTR-------RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGV-PLSdGGTVRLAAAVGYSNA 195
Cdd:PRK07799  83 GSYDPSRidallkgRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLfPMG-GSAVRLVRQIPYTVA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 196 LEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSI-AKFPMASlmhdrNAVLenANAYNKPGFHVASYNEImnv 274
Cdd:PRK07799 162 CDLLLTGRHITAAEAKEIGLIGHVVPDGQALDKALELAELInANGPLAV-----QAIL--RTIRETEGMHENEAFKI--- 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 665395261 275 tsdmitDMQEGVKRFKNSEIK-GPKtdswSIKEKTIPDWE 313
Cdd:PRK07799 232 ------DTKIGIPVFLSEDAKeGPR----AFAEKRAPNFQ 261
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 43-242 4.92e-37

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 133.24  E-value: 4.92e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAEAQRGSlnfllR 121
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDkAFSAGNDLKEQAAGGKRGW-----P 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTRRH-LRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIA 200
Cdd:PRK06494  81 ESGFGGLTSRFdLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMIL 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 665395261 201 TGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKF-PMA 242
Cdd:PRK06494 161 TGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACsPLS 203
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 43-251 7.38e-37

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 132.68  E-value: 7.38e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:PRK06688   7 LLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDELAPVN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EgsvgPTRR--HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIA 200
Cdd:PRK06688  87 R----FLRAiaALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 665395261 201 TGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAV 251
Cdd:PRK06688 163 LGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAI 213
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 43-244 7.02e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 130.09  E-value: 7.02e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFllRH 122
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSAYGAQD--AL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRhLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:PRK06190  84 PNPSPAWPA-MRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTG 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 665395261 203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASL 244
Cdd:PRK06190 163 DFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAV 204
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 42-251 2.46e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 128.62  E-value: 2.46e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELE----AEAQRGslN 117
Cdd:PRK05862   5 TILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMAdlsfMDVYKG--D 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 118 FLLRHEgsvgpTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALE 197
Cdd:PRK05862  83 YITNWE-----KVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMD 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 665395261 198 IIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAV 251
Cdd:PRK05862 158 LCLTGRMMDAAEAERAGLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAV 211
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 46-314 1.23e-32

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 121.31  E-value: 1.23e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261   46 EKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeaeaQRGSLNFLLRHEGS 125
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEM----YGEGPAHQALYREN 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  126 VGPTRRHLR---KPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:pfam00378  77 VLDLWTLLYtcpKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMhdrnAVLENANAYNKPGFHVASYNEIMNVTSDMIT-D 281
Cdd:pfam00378 157 RRISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALA----QLKKALNAKLEDALPTQLEAEARLFYSTFSKdD 232

                         250       260       270
                  ....*....|....*....|....*....|...
gi 665395261  282 MQEGVKRFknseikgpktdswsiKEKTIPDWEK 314
Cdd:pfam00378 233 IIEGLQAF---------------LEKRKPPWED 250
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 41-257 3.29e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 117.85  E-value: 3.29e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  41 RTVLVEKDSH-ITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeaeAQRGSLNFL 119
Cdd:PRK08138   7 DVVLLERPADgVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEF---ATAGAIEMY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 120 LRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEII 199
Cdd:PRK08138  84 LRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMA 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 665395261 200 ATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENANA 257
Cdd:PRK08138 164 LTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADA 221
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 48-239 3.36e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 118.27  E-value: 3.36e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  48 DSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEA-----EAQRGSLNFLLRH 122
Cdd:PRK06210  13 DSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTidpsdGRRDTDVRPFVGN 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRH----LRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLG-FFNRRlGVPLSDGGTVRLAAAVGYSNALE 197
Cdd:PRK06210  93 RRPDYQTRYHfltaLRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTtAFARR-GLIAEHGISWILPRLVGHANALD 171

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 665395261 198 IIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKF 239
Cdd:PRK06210 172 LLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARN 213
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
41-237 1.03e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 116.27  E-value: 1.03e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  41 RTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISqfEADDTSPVGVLYGIGGSFCAGYDLEEL-EAEAQRGSLNFL 119
Cdd:PRK08150   2 SLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFA--RLPEGVRAVVLHGEGDHFCAGLDLSELrERDAGEGMHHSR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 120 LRHEgsVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEII 199
Cdd:PRK08150  80 RWHR--VFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMM 157

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 665395261 200 ATGrRIYSG-EARRIGLVNRVVATGTALGQAVNLAFSIA 237
Cdd:PRK08150 158 LTG-RVYDAqEGERLGLAQYLVPAGEALDKAMELARRIA 195
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
43-244 1.56e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 113.53  E-value: 1.56e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTA-EQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLN-FLL 120
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALSDNDAvDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRARVGAFGGSpADI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 121 RHEGSVGPTR-----RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNA 195
Cdd:PRK09245  85 RQGYRHGIQRiplalYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARA 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 665395261 196 LEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASL 244
Cdd:PRK09245 165 AEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHAL 213
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 42-238 1.74e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 113.29  E-value: 1.74e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVE-KDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIG-GSFCAGYDLEE---LEAEAQRGSL 116
Cdd:PRK07657   4 NISVDyVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADLKEragMNEEQVRHAV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 117 NFLLRHEGSVgptrRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNAL 196
Cdd:PRK07657  84 SLIRTTMEMV----EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAK 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 665395261 197 EIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
Cdd:PRK07657 160 ELIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIAS 201
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
43-295 1.36e-27

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 108.24  E-value: 1.36e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQrNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGS-FCAGYDLEEL-EAEAQRGSLNFll 120
Cdd:PRK03580   5 LHTTRNGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKfFSAGWDLKAAaEGEAPDADFGP-- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 121 rhEGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEII 199
Cdd:PRK03580  82 --GGFAGLTEiFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 200 ATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAkfpmaslmhdrnavlenanayNKPGFHVASYNEIMNVTSDMi 279
Cdd:PRK03580 160 MTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLV---------------------NSAPLAIAALKEIYRETSEM- 217

                        250
                 ....*....|....*.
gi 665395261 280 tDMQEGVKRFKNSEIK 295
Cdd:PRK03580 218 -PVEEAYRYIRSGVLK 232
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
43-242 1.88e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 107.91  E-value: 1.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEEL----EAEAQRGSL- 116
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEkAFVAGADISEMkdlnEEEGRKFGLl 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 117 --NFLLRHEgsvgptrrHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSN 194
Cdd:PRK05809  86 gnKVFRKLE--------NLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGK 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 665395261 195 ALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA-KFPMA 242
Cdd:PRK05809 158 AKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAaNAPIA 206
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 32-221 3.18e-27

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 107.48  E-value: 3.18e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  32 SESQEGAPARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAe 110
Cdd:PRK06127   2 TMSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEkAFVSGADISQFEE- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 111 aQRGSLNFLLRHEGSVGPTRRHLR---KPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLA 187
Cdd:PRK06127  81 -SRSDAEAVAAYEQAVEAAQAALAdyaKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLV 159

                        170       180       190
                 ....*....|....*....|....*....|....
gi 665395261 188 AAVGYSNALEIIATGRRIYSGEARRIGLVNRVVA 221
Cdd:PRK06127 160 DLVGPSAAKDLFYTARRFDAAEALRIGLVHRVTA 193
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 43-289 9.29e-27

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 106.18  E-value: 9.29e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLRH 122
Cdd:PRK08139  13 LLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAARGLAYFRALFAR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAvlgffnrRLGVPLSDGG------TVRLAAAVGYSNAL 196
Cdd:PRK08139  93 CSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTA-------RFAVPGVNIGlfcstpMVALSRNVPRKQAM 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 197 EIIATGRRIYSGEARRIGLVNRVVATGtALGQAVN-LAFSIA-KFPMA----SLMHDRNAVLENANAYnkpgfHVASynE 270
Cdd:PRK08139 166 EMLLTGEFIDAATAREWGLVNRVVPAD-ALDAAVArLAAVIAaKSPAAvrigKEAFYRQAEMPLADAY-----AYAG--D 237

                        250       260
                 ....*....|....*....|
gi 665395261 271 IMnvTSDMIT-DMQEGVKRF 289
Cdd:PRK08139 238 VM--AENMMAeDAEEGIDAF 255
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 45-289 1.20e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 105.49  E-value: 1.20e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  45 VEKDSHITLIGLNReQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL---------EELEAEAQRGS 115
Cdd:PRK07658   6 VRVEDHVAVITLNH-PPANALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIkeftsvteaEQATELAQLGQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 LNFLlRHEgsvgptrrHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNA 195
Cdd:PRK07658  85 VTFE-RVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 196 LEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLmhdrNAVLENANAYNKPGFHVASYNEIMNVT 275
Cdd:PRK07658 156 LEMMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATT----RAVLELLQTTKSSSYYEGVKREAKIFG 231

                        250
                 ....*....|....*
gi 665395261 276 SDMIT-DMQEGVKRF 289
Cdd:PRK07658 232 EVFTSeDAKEGVQAF 246
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 39-251 1.72e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 105.81  E-value: 1.72e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQ------ 112
Cdd:PRK08290   2 EYEYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGSGTPGRDrdpgpd 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 113 -----------RGSLNFLLRHEGSV--GPTRR--HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAvlgFFNR---RL 174
Cdd:PRK08290  82 qhptlwwdgatKPGVEQRYAREWEVylGMCRRwrDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDA---FFSDpvvRM 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665395261 175 GVPlsdgGTVRLAAA--VGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAV 251
Cdd:PRK08290 159 GIP----GVEYFAHPweLGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAV 233
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 48-278 2.53e-26

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 105.37  E-value: 2.53e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  48 DSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQ------RGSLNFLLR 121
Cdd:PLN02664  15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEqsssgdRGRSGERLR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HE----GSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALE 197
Cdd:PLN02664  95 RKikflQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAME 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 198 IIATGRRIYSGEARRIGLVNRVVATGTALGQAVNL-AFSI-AKFPM------ASLMHDRNAVLENANAYnkpgfhVASYN 269
Cdd:PLN02664 175 LALTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRLiAEGIaAKSPLavtgtkAVLLRSRELSVEQGLDY------VATWN 248


                 ....*....
gi 665395261 270 EIMNVTSDM 278
Cdd:PLN02664 249 SAMLVSDDL 257
PLN02600 PLN02600
enoyl-CoA hydratase
 48-245 6.63e-26

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 103.35  E-value: 6.63e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  48 DSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYG-IGGSFCAGYDLEELE----AEAQrgslnFLLRH 122
Cdd:PLN02600   2 DSGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSsVPGVFCAGADLKERRkmspSEVQ-----KFVNS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 EGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATG 202
Cdd:PLN02600  77 LRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTG 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 665395261 203 RRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA-KFPMASLM 245
Cdd:PLN02600 157 RRIGAREAASMGLVNYCVPAGEAYEKALELAQEINqKGPLAIKM 200
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
41-257 7.11e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 98.96  E-value: 7.11e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  41 RTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL----EELEAEAQRGSL 116
Cdd:PRK08272  10 KTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLsayaEGSSSGGGGGAY 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 117 NFLLRHEGSVGP---------------TRR-----HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRL-G 175
Cdd:PRK08272  90 PGKRQAVNHLPDdpwdpmidyqmmsrfVRGfmslwHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVwG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 176 VPLSDGGTVRLaaavGYSNALEIIATGRRIYSGEARRIGLVNRVVATgTALGQAV-NLAFSIAKFPMASL-MHDR--NAV 251
Cdd:PRK08272 170 VPATGMWAYRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPP-EELDERTeRLVERIAAVPVNQLaMVKLavNSA 244


                 ....*.
gi 665395261 252 LENANA 257
Cdd:PRK08272 245 LLQQGV 250
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 43-242 7.36e-24

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 97.91  E-value: 7.36e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNfllrh 122
Cdd:PRK09674   4 LLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMAEKDLAATLN----- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 egsvGPTRRH------LRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNAL 196
Cdd:PRK09674  79 ----DPRPQLwqrlqaFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLAS 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 665395261 197 EIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKF-PMA 242
Cdd:PRK09674 155 QMVLTGESITAQQAQQAGLVSEVFPPELTLERALQLASKIARHsPLA 201
PLN02888 PLN02888
enoyl-CoA hydratase
 43-238 1.13e-23

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 97.90  E-value: 1.13e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKD-SHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEaEAQRGSLNflLR 121
Cdd:PLN02888  11 ILVPKSrNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTAAE-EVFKGDVK--DV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTRRhLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIAT 201
Cdd:PLN02888  88 ETDPVAQMER-CRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLT 166

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 665395261 202 GRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
Cdd:PLN02888 167 AMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIK 203
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 42-220 1.73e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 97.30  E-value: 1.73e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAG-----------YDLEELEAE 110
Cdd:PRK05995   5 TLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGadlnwmkkmagYSDDENRAD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 111 AQRgsLNFLLRhegsvgpTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGV------PLsdggtv 184
Cdd:PRK05995  85 ARR--LADMLR-------AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLipatisPY------ 149

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 665395261 185 rLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:PRK05995 150 -VIRAMGERAARRYFLTAERFDAAEALRLGLVHEVV 184
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 43-233 5.65e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 95.83  E-value: 5.65e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEA--EAQRGsLNFL 119
Cdd:PRK06144  10 LLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDkAFVAGTDIAQFRAfsTAEDA-VAYE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 120 LRHEGSVGpTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGF-FNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK06144  89 RRIDRVLG-ALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDM 167

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLA 233
Cdd:PRK06144 168 LFTARLLEAEEALAAGLVNEVVEDAALDARADALA 202
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 45-238 2.06e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 94.22  E-value: 2.06e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  45 VEKDSHITLIGLNREQQrNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSF-CAGYDLEeLEAEAQRGSLNFLLRHE 123
Cdd:PRK09076   7 LEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLN-LFADGDKAVAREMARRF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 124 GSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGR 203
Cdd:PRK09076  85 GEAFEALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGE 164

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 665395261 204 RIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
Cdd:PRK09076 165 RVDAATALRIGLVEEVVEKGEAREAALALAQKVAN 199
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
42-242 2.14e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 94.27  E-value: 2.14e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL-------EELEAEAQRG 114
Cdd:PRK06142   7 SFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLpamagvfGQLGKDGLAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 115 S----LNFLLRHEGSVGPTRRhLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVpLSDGGTV-RLAAA 189
Cdd:PRK06142  87 PrtdlRREILRLQAAINAVAD-CRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGM-VADVGSLqRLPRI 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 665395261 190 VGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVN-LAFSIA-KFPMA 242
Cdd:PRK06142 165 IGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDADALLAAAHaTAREIAaKSPLA 219
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 38-220 1.72e-21

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 91.99  E-value: 1.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  38 APARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEE--LEAEAQRGS 115
Cdd:PRK09120   5 NRWDTVKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEyfRETDAQPEI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 LNFLLRHEGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSN 194
Cdd:PRK09120  85 LQERIRREAYGWWRRlRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRD 164

                        170       180
                 ....*....|....*....|....*.
gi 665395261 195 ALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:PRK09120 165 ALYYIMTGETFTGRKAAEMGLVNESV 190
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
40-240 4.30e-21

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 90.80  E-value: 4.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  40 ARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFE-ADDTSPVgVLYGIGGSFCAGYDLEELEAEAQRGSLNF 118
Cdd:PRK08258  16 ARHFLWEVDDGVATITLNRPERKNPLTFESYAELRDLFRELVyADDVKAV-VLTGAGGNFCSGGDVHEIIGPLTKMDMPE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LL---RHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGtvrlAAA-----V 190
Cdd:PRK08258  95 LLaftRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAGADMG----ACAllpriI 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 665395261 191 GYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFP 240
Cdd:PRK08258 171 GQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGP 220
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 45-261 5.26e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 90.08  E-value: 5.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  45 VEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVgVLYGIGGSFCAGYDLE-ELEAEAQRGSLNFLLRHE 123
Cdd:PRK07854   4 VTRDGQVLTIELQRPERRNALNAELCEELREAVRKAVDESARAI-VLTGQGTVFCAGADLSgDVYADDFPDALIEMLHAI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 124 GSVGptrrhlrKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLsDGGTV-RLAAAVGYSNALEIIATG 202
Cdd:PRK07854  83 DAAP-------VPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIAL-DNWTIrRLSSLVGGGRARAMLLGA 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 665395261 203 RRIYSGEARRIGLVNRVvatGTaLGQAVNLAFSIAKFPMASLMHDRnAVLENANAYNKP 261
Cdd:PRK07854 155 EKLTAEQALATGMANRI---GT-LADAQAWAAEIAGLAPLALQHAK-RVLNDDGAIEEA 208
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 42-240 7.00e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 89.78  E-value: 7.00e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLR 121
Cdd:PRK05870   4 PVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGRPAEDGLRR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 -HEG--SVgptrRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK05870  84 iYDGflAV----ASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTAlgQAVNLAFSIAKFP 240
Cdd:PRK05870 160 LLFGMRFDAEAAVRHGLALMVADDPVA--AALELAAGPAAAP 199
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 34-220 2.32e-20

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 91.82  E-value: 2.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261   34 SQEGAP-ART-VLVEKDSHITLIGLNREQQR-NSIDANTAEQLTEAISQFEADDTSPVGVLY-GIGGSFCAGYDLEELEA 109
Cdd:TIGR02441   4 STSAALmARThRHYEVKGDVAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLIsGKPGSFVAGADIQMIAA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  110 EaQRGSLNFLLRHEGSVGPTR-RHLRKPLVCGISGFCVAGGLELALMCDLRVM--EDTAVLGFFNRRLGVPLSDGGTVRL 186
Cdd:TIGR02441  84 C-KTAQEVTQLSQEGQEMFERiEKSQKPIVAAISGSCLGGGLELALACHYRIAtkDRKTLLGLPEVMLGLLPGAGGTQRL 162

                         170       180       190
                  ....*....|....*....|....*....|....
gi 665395261  187 AAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:TIGR02441 163 PKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLV 196
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 42-238 2.54e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 89.29  E-value: 2.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL----EELEAEAQRGSLN 117
Cdd:PRK08260   5 TIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLsaggNTFDLDAPRTPVE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 118 FLLR-HEGSVGPTRR-----------HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGF-FNRRLGVPLSdGGTV 184
Cdd:PRK08260  85 ADEEdRADPSDDGVRdgggrvtlrifDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFvFGRRGIVPEA-ASSW 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 665395261 185 RLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
Cdd:PRK08260 164 FLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIAD 217
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 43-239 5.74e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 87.97  E-value: 5.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDS-HITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLN---F 118
Cdd:PRK05864  11 VLVDHPRpEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHVEGLTrptY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHE---GSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGG-TVRLAAAVGYSN 194
Cdd:PRK05864  91 ALRSMellDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTASELGlSYLLPRAIGSSR 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 665395261 195 ALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKF 239
Cdd:PRK05864 171 AFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGF 215
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
56-230 1.18e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 86.65  E-value: 1.18e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  56 LNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAE-----AQRGS----LNFLLRhegsv 126
Cdd:PRK07468  20 LNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGWMRAQmtadrATRIEearrLAMMLK----- 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 127 gpTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLG-VPLSDGGTVrlAAAVGYSNALEIIATGRRI 205
Cdd:PRK07468  95 --ALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGlIPATISPYV--VARMGEANARRVFMSARLF 170

                        170       180
                 ....*....|....*....|....*
gi 665395261 206 YSGEARRIGLVNRVVAtGTALGQAV 230
Cdd:PRK07468 171 DAEEAVRLGLLSRVVP-AERLDAAV 194
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 63-242 1.33e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 86.24  E-value: 1.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  63 NSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAEAQRGSLNFL--LRHegsVGPTRRHLRKPLVC 139
Cdd:PRK06143  29 NILGTPVILALTQALRWLAADPDVRVLVLRGAGEkAFIGGADIKEMATLDQASAEAFIsrLRD---LCDAVRHFPVPVIA 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 140 GISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPlSDGGTVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRV 219
Cdd:PRK06143 106 RIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGIP-SVIHAALLPRLIGWARTRWLLLTGETIDAAQALAWGLVDRV 184

                        170       180
                 ....*....|....*....|....*
gi 665395261 220 VATGtALGQAV-NLAFSIAKF-PMA 242
Cdd:PRK06143 185 VPLA-ELDAAVeRLAASLAGCgPQA 208
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
63-233 2.73e-19

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 88.41  E-value: 2.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  63 NSIDANTAEQLTEAISQFEADDTSPVGVLY-GIGGSFCAGYDLEELEA-----EAQRgslnflLRHEGSVGPTRRH-LRK 135
Cdd:PRK11154  29 NTLKAEFAEQVRAILKQLREDKELKGVVFIsGKPDNFIAGADINMLAAcktaqEAEA------LARQGQQLFAEIEaLPI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 136 PLVCGISGFCVAGGLELALMCDLRVMEDTA--VLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGRRIYSGEARRI 213
Cdd:PRK11154 103 PVVAAIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKL 182

                        170       180
                 ....*....|....*....|
gi 665395261 214 GLVNRVVATGTALGQAVNLA 233
Cdd:PRK11154 183 GLVDDVVPHSILLEVAVELA 202
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 56-244 1.02e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 83.89  E-value: 1.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  56 LNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLE------ELEAEAQRGSLNFLlrheGSVGPT 129
Cdd:PRK07511  18 LSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNrllenrAKPPSVQAASIDGL----HDWIRA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 130 RRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGRRIYSGE 209
Cdd:PRK07511  94 IRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAER 173

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 665395261 210 ARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASL 244
Cdd:PRK07511 174 LHALGVVNRLAEPGQALAEALALADQLAAGSPNAL 208
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
136-232 8.21e-18

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 84.14  E-value: 8.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 136 PLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGRRIYSGEARRIGL 215
Cdd:PRK11730 104 PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGA 183

                         90
                 ....*....|....*..
gi 665395261 216 VNRVVATGTALGQAVNL 232
Cdd:PRK11730 184 VDAVVAPEKLQEAALAL 200
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
42-238 1.62e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 80.57  E-value: 1.62e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAEAQRGS----L 116
Cdd:PRK05980   4 TVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDrAFSAGADIHEFSASVAAGAdvalR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 117 NFLLRHEGSvgpTRR--HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSN 194
Cdd:PRK05980  84 DFVRRGQAM---TARleAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKR 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 665395261 195 ALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAK 238
Cdd:PRK05980 161 ALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIR 204
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
42-244 7.20e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 79.61  E-value: 7.20e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL--------EELEAEAQ- 112
Cdd:PRK12478   6 TLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFgggfqhwgEAMMTDGRw 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 113 RGSLNFLLRHEGSVGPTRRHL-----RKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGF-FNRRLGVPLSDGGTVRL 186
Cdd:PRK12478  86 DPGKDFAMVTARETGPTQKFMaiwraSKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTpYSRMWGAYLTGMWLYRL 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 665395261 187 AAAVGYSNALeiiaTGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASL 244
Cdd:PRK12478 166 SLAKVKWHSL----TGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARIPLSQL 219
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
42-238 1.03e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 78.38  E-value: 1.03e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAE----------- 110
Cdd:PRK07509   4 RVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSpgnavkllfkr 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 111 -------AQRGSLNFllrhegsvgptrRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLG-VPlsD-G 181
Cdd:PRK07509  84 lpgnanlAQRVSLGW------------RRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGlVP--DmA 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 665395261 182 GTVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVVAtgTALGQAVNLAFSIAK 238
Cdd:PRK07509 150 GTVSLRGLVRKDVARELTYTARVFSAEEALELGLVTHVSD--DPLAAALALAREIAQ 204
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 43-290 1.04e-16

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 78.53  E-value: 1.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTsPVGVLYGIGGS--FCAGYDLEELEAeAQRGSLnfll 120
Cdd:PRK11423   6 VNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRPEI-RVVILRAPSGSkvWSAGHDIHELPS-GGRDPL---- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 121 rheGSVGPTRRHLR------KPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSN 194
Cdd:PRK11423  80 ---SYDDPLRQILRmiqkfpKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHI 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 195 ALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA-KFPMA-SLMHDRNAVLENANAYNKPGFHvaSYNEIM 272
Cdd:PRK11423 157 VKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISeKAPLAiAVIKEQLRVLGEAHPMNPDEFE--RIQGLR 234

                        250
                 ....*....|....*...
gi 665395261 273 NVTSDMiTDMQEGVKRFK 290
Cdd:PRK11423 235 RAVYDS-EDYQEGMNAFL 251
PLN02921 PLN02921
naphthoate synthase
 41-220 1.51e-14

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 73.28  E-value: 1.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  41 RTVLVEK--DSHITLIGLNREQQRNSIDANTAEQLTEAISqfEADDTSPVGV--LYGIGG-SFCAGYDleeleaEAQRGS 115
Cdd:PLN02921  65 TDIIYEKavGEGIAKITINRPERRNAFRPRTVKELQRAFN--DARDDSSVGViiLTGKGTkAFCSGGD------QAVRGK 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 lnfllrhEGSVGPTR-------------RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGG 182
Cdd:PLN02921 137 -------DGYVGPDDagrlnvldlqiqiRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYG 209

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 665395261 183 TVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:PLN02921 210 SSIMARLVGQKKAREMWFLARFYTASEALKMGLVNTVV 247
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 38-243 1.81e-14

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 72.22  E-value: 1.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  38 APARTVLVEKDSH---ITLIGLNREQQrNSIDANTAEQLTEAISQFEADDTSpVGVLYGIG---GSFCAGYDLEELEA-- 109
Cdd:PLN03214   6 PPGATPGVRVDRRpggIAVVWLAKEPV-NSMTLAMWRSLDDALTALENDPTV-RGVVFASGlrrDVFTAGNDIAELYApk 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 110 -------EAQRGSLNFLLRHegsvgptrrhLRKPL--VCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSD 180
Cdd:PLN03214  84 tsaaryaEFWLTQTTFLVRL----------LRSRLatVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIPVPK 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665395261 181 -GGTVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMAS 243
Cdd:PLN03214 154 fWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAA 217
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 42-240 1.98e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 69.17  E-value: 1.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVgVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLR 121
Cdd:PRK08140   5 TILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDGARAL-LLTGAGRGFCAGQDLADRDVTPGGAMPDLGES 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTRRHLR---KPLVCGISGFCVAGGLELALMCDLRVMEDTA--VLGFFnrRLG-VPLSdGGTVRLAAAVGYSNA 195
Cdd:PRK08140  84 IETFYNPLVRRLRalpLPVIAAVNGVAAGAGANLALACDIVLAARSAsfIQAFV--KIGlVPDS-GGTWFLPRLVGMARA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 665395261 196 LEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFP 240
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQP 205
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
43-251 4.53e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 67.89  E-value: 4.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSH---ITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGS---- 115
Cdd:PRK06023   5 ILVERPGAhpgVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDFLAAAMGGTsfgs 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 --LNFLLRHEGSvgptrrhlRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVlgffnrrLGVPLSDGGTVRLAAA---- 189
Cdd:PRK06023  85 eiLDFLIALAEA--------EKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSL-------FRTPFVDLALVPEAGSslla 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665395261 190 ---VGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAV 251
Cdd:PRK06023 150 prlMGHQRAFALLALGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLM 214
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 43-298 6.46e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 67.50  E-value: 6.46e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELeaeaqRGSLNFLLRH 122
Cdd:PRK06072   2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF-----APDFAIDLRE 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 123 egSVGPTRRHLR---KPLVCGISGFCVAGGLELALMCDLRVMEDTA--VLGFfnRRLGVPlSDGGTVRLAAAVGYSNALE 197
Cdd:PRK06072  77 --TFYPIIREIRfsdKIYISAINGVTAGACIGIALSTDFKFASRDVkfVTAF--QRLGLA-SDTGVAYFLLKLTGQRFYE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 198 IIATGRRIYSGEARRIGLVNrvvATGTALGQAVNLAFSIAKFPMAS-----------LMHDRNAVLEnanaynkpgfhva 266
Cdd:PRK06072 152 ILVLGGEFTAEEAERWGLLK---ISEDPLSDAEEMANRISNGPFQSyiaakrminlvLYNDLEEFLE------------- 215

                        250       260       270
                 ....*....|....*....|....*....|..
gi 665395261 267 sYNEIMNVTSDMITDMQEGVKRFKnsEIKGPK 298
Cdd:PRK06072 216 -YESAIQGYLGKTEDFKEGISSFK--EKREPK 244
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
43-257 7.86e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 67.45  E-value: 7.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSP-VGVLYGIGGSFCAGYDLEeleaeaQRGSLNFLLR 121
Cdd:PRK05981   6 VTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAEVrCLVLTGAGRGFCTGANLQ------GRGSGGRESD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVG--------PTRRHLRK---PLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLG-VPlsDGG-TVRLAA 188
Cdd:PRK05981  80 SGGDAGaaletayhPFLRRLRNlpcPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGlVP--DGGsTWLLPR 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665395261 189 AVGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASLMHDRNAVLENANA 257
Cdd:PRK05981 158 LVGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPEN 226
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
39-245 3.33e-12

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 65.49  E-value: 3.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQrNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEEleaeaqRGSLnf 118
Cdd:PRK06495   2 MMSQLKLEVSDHVAVVTLDNPPV-NALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKG------RPDV-- 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 llrhEGSVGPTRRHLR-------------KPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFfnRRLGVPLSDGG--T 183
Cdd:PRK06495  73 ----IKGPGDLRAHNRrtrecfhairecaKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGL--PEIDVGLAGGGkhA 146

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665395261 184 VRLaaaVGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIA-KFPMASLM 245
Cdd:PRK06495 147 MRL---FGHSLTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIAsKSPLATRL 206
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 83-244 6.48e-12

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 64.09  E-value: 6.48e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  83 DDTSPVgVLYGIGGSFCAGYDLEELE---AEAQRGSLNFLLRHEGSVGPtrrhLRKPLVCGISGFCVAGGLELALMCDLR 159
Cdd:PRK05869  50 DDVAAV-ILYGGHEIFSAGDDMPELRtlsAQEADTAARVRQQAVDAVAA----IPKPTVAAITGYALGAGLTLALAADWR 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 160 VMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKF 239
Cdd:PRK05869 125 VSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDG 204


                 ....*
gi 665395261 240 PMASL 244
Cdd:PRK05869 205 PPHAL 209
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 43-220 7.54e-12

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 64.53  E-value: 7.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDleeleaEAQRGslnfllr 121
Cdd:PRK07396  15 ILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDkAFCSGGD------QKVRG------- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTR-------------RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGvplS-DG--GTVR 185
Cdd:PRK07396  82 YGGYVDDDGvprlnvldlqrliRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVG---SfDGgyGASY 158

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 665395261 186 LAAAVGYSNALEIIATGRRIYSGEARRIGLVNRVV 220
Cdd:PRK07396 159 LARIVGQKKAREIWFLCRQYDAQEALDMGLVNTVV 193
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 43-244 1.06e-11

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 63.83  E-value: 1.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEaQRGSLNF---- 118
Cdd:PRK07110   7 ELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGLLSL-QTGKGTFtean 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEgsvgptrRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNALEI 198
Cdd:PRK07110  86 LYSLA-------LNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEM 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTALGQAVNLAFSIAKFPMASL 244
Cdd:PRK07110 159 LLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSL 204
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
39-216 1.71e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 63.55  E-value: 1.71e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  39 PARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNF 118
Cdd:PRK07827   4 VDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPYDAA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 119 LLRHEGSVGPTRR--HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGV-PLSDGGTV--RL--AAAVG 191
Cdd:PRK07827  84 VARAREMTALLRAivELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVaPAIISLTLlpRLspRAAAR 163

                        170       180
                 ....*....|....*....|....*
gi 665395261 192 YsnaleiIATGRRIYSGEARRIGLV 216
Cdd:PRK07827 164 Y------YLTGEKFGAAEAARIGLV 182
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 50-220 2.49e-09

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 57.48  E-value: 2.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261   50 HITLiglNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAEAQRGS------------- 115
Cdd:pfam16113   3 VITL---NRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGErAFCAGGDVRALYEAAKAGGgeagrdffreeyr 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  116 LNFLLrHegsvgptrrHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVL-------GFFnrrlgvPlsD-GGTV--- 184
Cdd:pfam16113  80 LNYLI-A---------TYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFampetaiGLF------P--DvGGSYfls 141

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 665395261  185 RLAAAVGYSNALeiiaTGRRIYSGEARRIGLVNRVV 220
Cdd:pfam16113 142 RLPGELGLYLAL----TGARLNGADALAAGLATHYV 173
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 42-225 5.21e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 56.19  E-value: 5.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVgVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLR 121
Cdd:PRK07659   7 SVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSAHIV-VLRGNGRGFSAGGDIKMMLSSNDESKFDGVMN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGF-FNrrlGVPL--SDGGTVRLAAAVGYSNALEI 198
Cdd:PRK07659  86 TISEIVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMnFI---GIGLipDGGGHFFLQKRVGENKAKQI 162

                        170       180
                 ....*....|....*....|....*..
gi 665395261 199 IATGRRIYSGEARRIGLVNRVVATGTA 225
Cdd:PRK07659 163 IWEGKKLSATEALDLGLIDEVIGGDFQ 189
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
63-237 1.34e-08

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 54.59  E-value: 1.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  63 NSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSL---------NFLLRHEGSVgptrrhl 133
Cdd:PRK07938  23 NALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALidanrgcfaAFRAVYECAV------- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 134 rkPLVCGISGFCVAGGLELALMCDLRVMEDTAvlgffnrRLGVPLSD----GGTVRLAAAVGYSNALEIIATGRRIYSGE 209
Cdd:PRK07938  96 --PVIAAVHGFCLGGGIGLVGNADVIVASDDA-------TFGLPEVDrgalGAATHLQRLVPQHLMRALFFTAATITAAE 166

                        170       180
                 ....*....|....*....|....*...
gi 665395261 210 ARRIGLVNRVVATGTALGQAVNLAFSIA 237
Cdd:PRK07938 167 LHHFGSVEEVVPRDQLDEAALEVARKIA 194
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 31-104 4.37e-08

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 54.03  E-value: 4.37e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665395261  31 ESESQEGAPARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDL 104
Cdd:PLN02874   1 MAQQVQNPAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDL 74
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 36-222 3.56e-07

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 51.26  E-value: 3.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  36 EGAPARTVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGS 115
Cdd:PLN02988   4 EMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 LNF---LLRHEGSVGPTRRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGVPLSDGGTVRLAAAVGY 192
Cdd:PLN02988  84 WRLganFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF 163

                        170       180       190
                 ....*....|....*....|....*....|
gi 665395261 193 SNALeIIATGRRIYSGEARRIGLVNRVVAT 222
Cdd:PLN02988 164 FGEY-VGLTGARLDGAEMLACGLATHFVPS 192
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 42-220 2.57e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 47.81  E-value: 2.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQRGSLNFLLR 121
Cdd:PRK07260   3 HIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 122 HEGSVGPTR---RHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAvlGFFNRRLGVPLSD--GGTVRLAAAVGYSNAL 196
Cdd:PRK07260  83 IAELVNEISfaiKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKT--KFIQAFVGVGLAPdaGGLFLLTRAIGLNRAT 160

                        170       180
                 ....*....|....*....|....
gi 665395261 197 EIIATGRRIYSGEARRIGLVNRVV 220
Cdd:PRK07260 161 HLAMTGEALTAEKALEYGFVYRVA 184
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 43-222 6.67e-06

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 47.12  E-value: 6.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  43 VLVEKDSHITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGG-SFCAGYDLEELEAEAQRGS------ 115
Cdd:PRK05617   5 VLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGErGFCAGGDIRALYEAARAGDplaadr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 116 -------LNFLLrhegsvgptrRHLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVL-------GFFnrrlgvPlsD- 180
Cdd:PRK05617  85 ffreeyrLNALI----------ARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMampetgiGFF------P--Dv 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 665395261 181 GGTVRLAAA---VGYSNALeiiaTGRRIYSGEARRIGLVNRVVAT 222
Cdd:PRK05617 147 GGTYFLSRApgaLGTYLAL----TGARISAADALYAGLADHFVPS 187
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 42-216 4.93e-05

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 44.03  E-value: 4.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  42 TVLVEKDSH-ITLIGLNREQQRNSIDANTAEQLTEAISQFEADDTSPVGVLYGIGGSFCAGYDLEELEAEAQrgslnflL 120
Cdd:PRK05674   6 TIELIRDPRgFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAWMQQSAD-------L 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 121 RHEGSVGPTRR---------HLRKPLVCGISGFCVAGGLELALMCDLRVMEDTAVLGFFNRRLGV-PLSDGGTVrlAAAV 190
Cdd:PRK05674  79 DYNTNLDDARElaelmynlyRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLaPAVISPFV--VKAI 156

                        170       180
                 ....*....|....*....|....*.
gi 665395261 191 GYSNALEIIATGRRIYSGEARRIGLV 216
Cdd:PRK05674 157 GERAARRYALTAERFDGRRARELGLL 182
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 76-238 2.60e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 38.54  E-value: 2.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261  76 AISQFEADdTSPVGVLYGI--GGSFCAGYDLeeleAEAQRGSLNFLLRHE-----GSVGPTRRHLRKPLVCGISGFCVAG 148
Cdd:PLN02267  34 ALRQVKSQ-ATPGSVLITTaeGKFFSNGFDL----AWAQAAGSAPSRLHLmvaklRPLVADLISLPMPTIAAVTGHASAA 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665395261 149 GLELALMCDLRVM-EDTAVLGFFNRRLGVPLSDGGTVRLAAAVGYSNAL-EIIATGRRIYSGEARRIGLVNrvVATGTAL 226
Cdd:PLN02267 109 GFILALSHDYVLMrKDRGVLYMSEVDIGLPLPDYFMALLRAKIGSPAARrDVLLRAAKLTAEEAVEMGIVD--SAHDSAE 186

                        170
                 ....*....|....*
gi 665395261 227 G---QAVNLAFSIAK 238
Cdd:PLN02267 187 EtveAAVRLGEELAA 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH