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Conserved domains on  [gi|453229796|ref|NP_001263530|]
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Uncharacterized protein CELE_R05D7.3 [Caenorhabditis elegans]

Protein Classification

TMEM200 family protein( domain architecture ID 8052)

TMEM200 family protein is a DUF2371 domain-containing protein; similar to Homo sapiens transmembrane protein 200B

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2371 super family cl10871
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 12-94 1.57e-10

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


The actual alignment was detected with superfamily member pfam10177:

Pssm-ID: 462979  Cd Length: 141  Bit Score: 57.72  E-value: 1.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453229796   12 VIFGCIIICVGLAMTVLGYF--DKHFSEKVEIIDGSEKVSYDR---------MIQYQL-KSMQYLGPILMGIGSFILIIA 79
Cdd:pfam10177  44 ALLGILVLLVGIAMAVLGYWphEVAQLGSRNNNSSNSTAEMSRdhsgflarfLEQYLHsDKMKVFGPLIMGIGIFLFICA 123

                          90
                  ....*....|....*
gi 453229796   80 CVVTLESRDKHAQII 94
Cdd:pfam10177 124 NAVLHENRDKETKII 138
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 12-94 1.57e-10

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 57.72  E-value: 1.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453229796   12 VIFGCIIICVGLAMTVLGYF--DKHFSEKVEIIDGSEKVSYDR---------MIQYQL-KSMQYLGPILMGIGSFILIIA 79
Cdd:pfam10177  44 ALLGILVLLVGIAMAVLGYWphEVAQLGSRNNNSSNSTAEMSRdhsgflarfLEQYLHsDKMKVFGPLIMGIGIFLFICA 123

                          90
                  ....*....|....*
gi 453229796   80 CVVTLESRDKHAQII 94
Cdd:pfam10177 124 NAVLHENRDKETKII 138
 
Name Accession Description Interval E-value
DUF2371 pfam10177
Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from ...
 12-94 1.57e-10

Uncharacterized conserved protein (DUF2371); This is a family of proteins conserved from nematodes to humans. The function is not known.


Pssm-ID: 462979  Cd Length: 141  Bit Score: 57.72  E-value: 1.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453229796   12 VIFGCIIICVGLAMTVLGYF--DKHFSEKVEIIDGSEKVSYDR---------MIQYQL-KSMQYLGPILMGIGSFILIIA 79
Cdd:pfam10177  44 ALLGILVLLVGIAMAVLGYWphEVAQLGSRNNNSSNSTAEMSRdhsgflarfLEQYLHsDKMKVFGPLIMGIGIFLFICA 123

                          90
                  ....*....|....*
gi 453229796   80 CVVTLESRDKHAQII 94
Cdd:pfam10177 124 NAVLHENRDKETKII 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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