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Conserved domains on  [gi|453232650|ref|NP_001263911|]
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Serpentine Receptor, class H [Caenorhabditis elegans]

Protein Classification

serpentine receptor domain-containing protein( domain architecture ID 27798)

serpentine receptor domain-containing protein which belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srh super family cl11665
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 1-111 4.13e-25

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10318:

Pssm-ID: 416353  Cd Length: 302  Bit Score: 95.69  E-value: 4.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232650    1 MMVSESVPTIQVGSFFFLNVYNLIFASPSGISRKTVQMQHRLVIALIIQTSVSLFFFLVPINLIISFVFFHHQNQFHNNL 80
Cdd:pfam10318 190 IVLLILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNL 269

                          90       100       110
                  ....*....|....*....|....*....|.
gi 453232650   81 IFFALAIHGIASTLIMVFVHKPYRDFALSPF 111
Cdd:pfam10318 270 LFIIISLHGLLSTIAMLLVHKPYRKFVLSLF 300
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 1-111 4.13e-25

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 95.69  E-value: 4.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232650    1 MMVSESVPTIQVGSFFFLNVYNLIFASPSGISRKTVQMQHRLVIALIIQTSVSLFFFLVPINLIISFVFFHHQNQFHNNL 80
Cdd:pfam10318 190 IVLLILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNL 269

                          90       100       110
                  ....*....|....*....|....*....|.
gi 453232650   81 IFFALAIHGIASTLIMVFVHKPYRDFALSPF 111
Cdd:pfam10318 270 LFIIISLHGLLSTIAMLLVHKPYRKFVLSLF 300
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 1-111 4.13e-25

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 95.69  E-value: 4.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232650    1 MMVSESVPTIQVGSFFFLNVYNLIFASPSGISRKTVQMQHRLVIALIIQTSVSLFFFLVPINLIISFVFFHHQNQFHNNL 80
Cdd:pfam10318 190 IVLLILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNL 269

                          90       100       110
                  ....*....|....*....|....*....|.
gi 453232650   81 IFFALAIHGIASTLIMVFVHKPYRDFALSPF 111
Cdd:pfam10318 270 LFIIISLHGLLSTIAMLLVHKPYRKFVLSLF 300
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 32-104 1.95e-04

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 38.98  E-value: 1.95e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 453232650   32 SRKTVQMQHRLVIALIIQTSVSLFFFLVPINLIISFVFFHHQNQFHNNLIFFALAIHGIASTLIMVFVHKPYR 104
Cdd:pfam10326 231 SEKTRKLQKQLFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYR 303
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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