|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
175-582 |
3.24e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 3.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 175 SISLLDCSLRNVTFLSDAKIFDNVSLHGLVISSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDL 254
Cdd:COG4886 24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 255 ANNKikalgtaDFVGLTSLVYLELSNNQISSISQrTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQclsLRQLDLQANNLN 334
Cdd:COG4886 104 SGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTN---LKSLDLSNNQLT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 335 GpLSEqTLPGMRNLESLNLNRNLIKSIQnKALANFSRLVSLSLRHNQIDVLqDHAFFGLGALDSLDLSYNGIVAISSasL 414
Cdd:COG4886 173 D-LPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 415 QHLSRLTVLDLTHNFLRALTSdlIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQES 494
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 495 QLHSSLSASCVTPPRLEGAPLLQVPVETLSCDMDNVEKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLI 574
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
|
....*...
gi 665402320 575 LTWLLNLS 582
Cdd:COG4886 405 LALLDAVN 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
241-455 |
4.99e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 72.13 E-value: 4.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 241 NALSTLSALERLDLANNKIKALgtADFVGLTSLVYLELSNNQISSISQrtFVNLRKLEVLKLGGNRLgdyaQSLRSLSQC 320
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI----SVVEGLENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 321 LSLRQLDLQANNLngPLSEQTLPGMRNLESLnlnrnliksiqnkalanfsrlvSLSLRHnqidvlqdhaffglgaldsLD 400
Cdd:cd21340 90 TNLEELHIENQRL--PPGEKLTFDPRSLAAL----------------------SNSLRV-------------------LN 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 665402320 401 LSYNGIVAISSasLQHLSRLTVLDLTHNFLRALT--SDLIAPLPSLRELRLAGNDIS 455
Cdd:cd21340 127 ISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVC 181
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
249-307 |
3.32e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 3.32e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 665402320 249 LERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL 307
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
223-430 |
1.44e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 68.34 E-value: 1.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 223 GPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQIS-SISQRTFvNLRKLEVLK 301
Cdd:PLN00113 380 GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKW-DMPSLQMLS 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 302 LGGNR-LGDYAQSLRSLSqclsLRQLDLQANNLNG--PLSEQTLPgmrNLESLNLNRNLIKSIQNKALANFSRLVSLSLR 378
Cdd:PLN00113 459 LARNKfFGGLPDSFGSKR----LENLDLSRNQFSGavPRKLGSLS---ELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 379 HNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFL 430
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
476-526 |
6.91e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 49.35 E-value: 6.91e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 476 NPLSCDCSIRPFAEWLQESQ-LHSSLSASCVTPPRLEGaPLLQVPVETLSCD 526
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEhLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
449-536 |
1.58e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 55.47 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 449 LAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQESQLH--SSLSASCVTPPRLEGAPLLQVPVETLSCD 526
Cdd:TIGR00864 2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKvrQPEAALCAGPGALAGQPLLGIPLLDSGCD 81
|
90
....*....|..
gi 665402320 527 MDNVE--KDNAN 536
Cdd:TIGR00864 82 EEYVAclKDNSS 93
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
175-582 |
3.24e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.33 E-value: 3.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 175 SISLLDCSLRNVTFLSDAKIFDNVSLHGLVISSGEIKRVHKSAFLGIRGPLQALGLPGNALMSVPWNALSTLSALERLDL 254
Cdd:COG4886 24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 255 ANNKikalgtaDFVGLTSLVYLELSNNQISSISQrTFVNLRKLEVLKLGGNRLGDYAQSLRSLSQclsLRQLDLQANNLN 334
Cdd:COG4886 104 SGNE-------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTN---LKSLDLSNNQLT 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 335 GpLSEqTLPGMRNLESLNLNRNLIKSIQnKALANFSRLVSLSLRHNQIDVLqDHAFFGLGALDSLDLSYNGIVAISSasL 414
Cdd:COG4886 173 D-LPE-ELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 415 QHLSRLTVLDLTHNFLRALTSdlIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQES 494
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 495 QLHSSLSASCVTPPRLEGAPLLQVPVETLSCDMDNVEKDNANIMQHLETLAKPNQTSPIKDLSEEIILHELHFSTDYGLI 574
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLT 404
|
....*...
gi 665402320 575 LTWLLNLS 582
Cdd:COG4886 405 LALLDAVN 412
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
241-455 |
4.99e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 72.13 E-value: 4.99e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 241 NALSTLSALERLDLANNKIKALgtADFVGLTSLVYLELSNNQISSISQrtFVNLRKLEVLKLGGNRLgdyaQSLRSLSQC 320
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI----SVVEGLENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 321 LSLRQLDLQANNLngPLSEQTLPGMRNLESLnlnrnliksiqnkalanfsrlvSLSLRHnqidvlqdhaffglgaldsLD 400
Cdd:cd21340 90 TNLEELHIENQRL--PPGEKLTFDPRSLAAL----------------------SNSLRV-------------------LN 126
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 665402320 401 LSYNGIVAISSasLQHLSRLTVLDLTHNFLRALT--SDLIAPLPSLRELRLAGNDIS 455
Cdd:cd21340 127 ISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVC 181
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
225-380 |
2.68e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 67.12 E-value: 2.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 225 LQALGLPGNALMSVPwnALSTLSALERLDLANNKIKALGtadfvGLTSLVYLE---LSNNQISSISQrtFVNLRKLEVLK 301
Cdd:cd21340 26 LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIE-----NLENLVNLKklyLGGNRISVVEG--LENLTNLEELH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 302 LGGNRLG-------DYAqSLRSLSQClsLRQLDLQANNLNgplSEQTLPGMRNLESLNLNRNLIKSIQN--KALANFSRL 372
Cdd:cd21340 97 IENQRLPpgekltfDPR-SLAALSNS--LRVLNISGNNID---SLEPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSL 170
|
....*...
gi 665402320 373 VSLSLRHN 380
Cdd:cd21340 171 RELDLTGN 178
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
249-307 |
3.32e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 3.32e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 665402320 249 LERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL 307
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
370-428 |
3.39e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 3.39e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 665402320 370 SRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHN 428
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
240-462 |
7.69e-12 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 68.28 E-value: 7.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 240 WNALSTLSALERLDLANNKIKALGTADFV----GLTSLVYLELSNNQISSisqRTFVNL-------RKLEVLKLGGNRLG 308
Cdd:COG5238 201 AEALTQNTTVTTLWLKRNPIGDEGAEILAealkGNKSLTTLDLSNNQIGD---EGVIALaealknnTTVETLYLSGNQIG 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 309 dyAQSLRSLSqclslrqldlqannlngplseQTLPGMRNLESLNLNRNLIKSIQNKALANfsrlvslSLRHNQIdvlqdh 388
Cdd:COG5238 278 --AEGAIALA---------------------KALQGNTTLTSLDLSVNRIGDEGAIALAE-------GLQGNKT------ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 389 affglgaLDSLDLSYNGI-----VAISSAsLQHLSRLTVLDLTHNFLRALTSDLIAPL----PSLRELRLAGNDISIVAR 459
Cdd:COG5238 322 -------LHTLNLAYNGIgaqgaIALAKA-LQENTTLHSLDLSDNQIGDEGAIALAKYlegnTTLRELNLGKNNIGKQGA 393
|
...
gi 665402320 460 NAM 462
Cdd:COG5238 394 EAL 396
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
270-479 |
1.03e-11 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 67.00 E-value: 1.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 270 LTSLVYLELSNNQISSISQRTFVNLRK---LEVLKLGGNRLGD-----YAQSLRSLSqcLSLRQLDLQANNLNGPLSEQ- 340
Cdd:cd00116 80 GCGLQELDLSDNALGPDGCGVLESLLRsssLQELKLNNNGLGDrglrlLAKGLKDLP--PALEKLVLGRNRLEGASCEAl 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 341 --TLPGMRNLESLNLNRNlikSIQNKALanfsRLVSLSLRHNQidvlqdhaffglgALDSLDLSYNGI----VAISSASL 414
Cdd:cd00116 158 akALRANRDLKELNLANN---GIGDAGI----RALAEGLKANC-------------NLEVLDLNNNGLtdegASALAETL 217
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665402320 415 QHLSRLTVLDLTHNFLR-----ALTSDLIAPLPSLRELRLAGNDISIVA----RNAMDGARELESLQMQENPLS 479
Cdd:cd00116 218 ASLKSLEVLNLGDNNLTdagaaALASALLSPNISLLTLSLSCNDITDDGakdlAEVLAEKESLLELDLRGNKFG 291
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
223-430 |
1.44e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 68.34 E-value: 1.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 223 GPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQIS-SISQRTFvNLRKLEVLK 301
Cdd:PLN00113 380 GNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQgRINSRKW-DMPSLQMLS 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 302 LGGNR-LGDYAQSLRSLSqclsLRQLDLQANNLNG--PLSEQTLPgmrNLESLNLNRNLIKSIQNKALANFSRLVSLSLR 378
Cdd:PLN00113 459 LARNKfFGGLPDSFGSKR----LENLDLSRNQFSGavPRKLGSLS---ELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 379 HNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFL 430
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
346-406 |
1.59e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 60.23 E-value: 1.59e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665402320 346 RNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGI 406
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
242-455 |
5.36e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 66.41 E-value: 5.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 242 ALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDyaQSLRSLSQCL 321
Cdd:PLN00113 327 ALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEG--EIPKSLGACR 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 322 SLRQLDLQANNLNGPL---------------SEQTLPG--------MRNLESLNLNRN-----LIKSIQNKALANfsrlv 373
Cdd:PLN00113 405 SLRRVRLQDNSFSGELpseftklplvyfldiSNNNLQGrinsrkwdMPSLQMLSLARNkffggLPDSFGSKRLEN----- 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 374 sLSLRHNQIDVLQDHAFFGLGALDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGND 453
Cdd:PLN00113 480 -LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQ 558
|
..
gi 665402320 454 IS 455
Cdd:PLN00113 559 LS 560
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
245-455 |
6.64e-11 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 66.02 E-value: 6.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 245 TLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLgdYAQSLRSLSQCLSLR 324
Cdd:PLN00113 138 SIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQL--VGQIPRELGQMKSLK 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 325 QLDLQANNLNGPLSEQtLPGMRNLESLNL-NRNLIKSIQNkALANFSRLVSLSLRHNQIDVLQDHAFFGLGALDSLDLSY 403
Cdd:PLN00113 216 WIYLGYNNLSGEIPYE-IGGLTSLNHLDLvYNNLTGPIPS-SLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSD 293
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 404 NGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDIS 455
Cdd:PLN00113 294 NSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFS 345
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
396-454 |
4.90e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.99 E-value: 4.90e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 665402320 396 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDI 454
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
239-441 |
1.79e-09 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 60.06 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 239 PWNALSTLSALERLDLANNKIKALGTAdFV--GLTS----LVYLELSNNQISSISQR----TFVNLRKLEVLKLGGNRLG 308
Cdd:cd00116 100 VLESLLRSSSLQELKLNNNGLGDRGLR-LLakGLKDlppaLEKLVLGRNRLEGASCEalakALRANRDLKELNLANNGIG 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 309 DyaQSLRSLSQCL----SLRQLDLQANNLN----GPLSEqTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRhn 380
Cdd:cd00116 179 D--AGIRALAEGLkancNLEVLDLNNNGLTdegaSALAE-TLASLKSLEVLNLGDNNLTDAGAAALASALLSPNISLL-- 253
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665402320 381 qidvlqdhaffglgaldSLDLSYNGIVAISSASL----QHLSRLTVLDLTHNFLRALTSDLIAPL 441
Cdd:cd00116 254 -----------------TLSLSCNDITDDGAKDLaevlAEKESLLELDLRGNKFGEEGAQLLAES 301
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
225-283 |
3.83e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 3.83e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 665402320 225 LQALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQI 283
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
242-479 |
1.11e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.09 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 242 ALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRL-GDYAQSLRSLSQc 320
Cdd:PLN00113 255 SLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFtGKIPVALTSLPR- 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 321 lsLRQLDLQANNLNGPLSeQTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQID----------------V 384
Cdd:PLN00113 334 --LQVLQLWSNKFSGEIP-KNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEgeipkslgacrslrrvR 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 385 LQDHAFFG--------LGALDSLDLSYNGIVA-ISSA-----SLQHLS-----------------RLTVLDLTHNFLRAL 433
Cdd:PLN00113 411 LQDNSFSGelpseftkLPLVYFLDISNNNLQGrINSRkwdmpSLQMLSlarnkffgglpdsfgskRLENLDLSRNQFSGA 490
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 665402320 434 TSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLS 479
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLS 536
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
219-455 |
1.27e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 58.71 E-value: 1.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 219 LGIRGPLQALGLPGNALMSVPWNALSTLSALERLDLANNKIKA----------------LGTADFVG--------LTSLV 274
Cdd:PLN00113 160 IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGqiprelgqmkslkwiyLGYNNLSGeipyeiggLTSLN 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 275 YLELSNNQISSISQRTFVNLRKLEVLKLGGNRL-GDYAQSLRSLSQCLSlrqLDLQANNLNGPLSEQTLPgMRNLESLNL 353
Cdd:PLN00113 240 HLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLsGPIPPSIFSLQKLIS---LDLSDNSLSGEIPELVIQ-LQNLEILHL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 354 NRNLIKSIQNKALANFSRLVSLSLRHNQI--DVLQDhaffgLGA---LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHN 428
Cdd:PLN00113 316 FSNNFTGKIPVALTSLPRLQVLQLWSNKFsgEIPKN-----LGKhnnLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSN 390
|
250 260
....*....|....*....|....*..
gi 665402320 429 FLRALTSDLIAPLPSLRELRLAGNDIS 455
Cdd:PLN00113 391 SLEGEIPKSLGACRSLRRVRLQDNSFS 417
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
271-333 |
1.91e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.91e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665402320 271 TSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNRLGDYaqSLRSLSQCLSLRQLDLQANNL 333
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTL--SPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
322-382 |
2.06e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 2.06e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665402320 322 SLRQLDLQANNLNGpLSEQTLPGMRNLESLNLNRNLIKSIQNKALANFSRLVSLSLRHNQI 382
Cdd:pfam13855 2 NLRSLDLSNNRLTS-LDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
476-526 |
6.91e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 49.35 E-value: 6.91e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 476 NPLSCDCSIRPFAEWLQESQ-LHSSLSASCVTPPRLEGaPLLQVPVETLSCD 526
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEhLQDPVDLRCASPSSLRG-PLLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
449-536 |
1.58e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 55.47 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 449 LAGNDISIVARNAMDGARELESLQMQENPLSCDCSIRPFAEWLQESQLH--SSLSASCVTPPRLEGAPLLQVPVETLSCD 526
Cdd:TIGR00864 2 ISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKvrQPEAALCAGPGALAGQPLLGIPLLDSGCD 81
|
90
....*....|..
gi 665402320 527 MDNVE--KDNAN 536
Cdd:TIGR00864 82 EEYVAclKDNSS 93
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
273-479 |
3.28e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 54.08 E-value: 3.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 273 LVYLELSNNQIS-SISQRTFvNLRKLEVLKLGGNRL-GDYAQSLRSLSQclSLRQLDLQANNLNGPLSEQTLPgmrNLES 350
Cdd:PLN00113 71 VVSIDLSGKNISgKISSAIF-RLPYIQTINLSNNQLsGPIPDDIFTTSS--SLRYLNLSNNNFTGSIPRGSIP---NLET 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 351 LNLNRNLIKSIQNKALANFSRLVSLSLRHNqidVLQDHAFFGLGALDSLD---LSYNGIVAISSASLQHLSRLTVLDLTH 427
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGN---VLVGKIPNSLTNLTSLEfltLASNQLVGQIPRELGQMKSLKWIYLGY 221
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 665402320 428 NFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPLS 479
Cdd:PLN00113 222 NNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS 273
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
396-455 |
2.01e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 48.27 E-value: 2.01e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 396 LDSLDLSYNGIVAISSASLQHLSRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDIS 455
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLS 503
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
418-478 |
7.21e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 7.21e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665402320 418 SRLTVLDLTHNFLRALTSDLIAPLPSLRELRLAGNDISIVARNAMDGARELESLQMQENPL 478
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
151-334 |
4.17e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 43.50 E-value: 4.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 151 HTLRCNIDLHGMMLLADRLRTSPYSISLLDCSLRNvtfLSDAKIFDnvsLHGLVISSGEIKRVHKSaflgiRGPLQALGL 230
Cdd:cd00116 114 KLNNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNR---LEGASCEA---LAKALRANRDLKELNLA-----NNGIGDAGI 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 231 PGNALmsvpwnALSTLSALERLDLANNKIKALGTADFVG----LTSLVYLELSNNQISSISQRTFVN-----LRKLEVLK 301
Cdd:cd00116 183 RALAE------GLKANCNLEVLDLNNNGLTDEGASALAEtlasLKSLEVLNLGDNNLTDAGAAALASallspNISLLTLS 256
|
170 180 190
....*....|....*....|....*....|....*
gi 665402320 302 LGGNRLGDYA--QSLRSLSQCLSLRQLDLQANNLN 334
Cdd:cd00116 257 LSCNDITDDGakDLAEVLAEKESLLELDLRGNKFG 291
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
227-307 |
1.54e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 42.11 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 227 ALGLPGNALMSVPWNALSTLSALERLDLANNKIKALGTADFVGLTSLVYLELSNNQISSISQRTFVNLRKLEVLKLGGNR 306
Cdd:PLN03150 422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501
|
.
gi 665402320 307 L 307
Cdd:PLN03150 502 L 502
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
156-314 |
4.48e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.54 E-value: 4.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 156 NIDLHGMMLLADRLRtSPYSISLLDCSLRNVT-----FLSDAkIFDNVSLHGLVISSGEIKRVHKSAF---LGIRGPLQA 227
Cdd:COG5238 247 QIGDEGVIALAEALK-NNTTVETLYLSGNQIGaegaiALAKA-LQGNTTLTSLDLSVNRIGDEGAIALaegLQGNKTLHT 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665402320 228 LGLPGNALMSVPWN----ALSTLSALERLDLANNKI-----KALGTAdFVGLTSLVYLELSNNQISSISQRTFV---NLR 295
Cdd:COG5238 325 LNLAYNGIGAQGAIalakALQENTTLHSLDLSDNQIgdegaIALAKY-LEGNTTLRELNLGKNNIGKQGAEALIdalQTN 403
|
170
....*....|....*....
gi 665402320 296 KLEVLKLGGNRLGDYAQSL 314
Cdd:COG5238 404 RLHTLILDGNLIGAEAQQR 422
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
249-287 |
6.34e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 6.34e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 665402320 249 LERLDLANNKIKALGtaDFVGLTSLVYLELS-NNQISSIS 287
Cdd:pfam12799 3 LEVLDLSNNQITDIP--PLAKLPNLETLDLSgNNKITDLS 40
|
|
| |
