|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
33-350 |
1.22e-169 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 474.55 E-value: 1.22e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 33 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIA 112
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 113 SASRVTAVIPCFPYARQDKKDKAnaqsRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIK 192
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRP----REPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 193 ENipEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRL 272
Cdd:COG0462 157 SK--DLEDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEAL 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665410166 273 VEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRdCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:COG0462 235 KEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKR-CDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
36-349 |
1.98e-158 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 446.10 E-value: 1.98e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASAS 115
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 116 RVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENI 195
Cdd:PRK01259 81 RITAVIPYFGYARQDRKAR----SRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 196 PEwkNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEA 275
Cdd:PRK01259 157 LE--NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKER 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665410166 276 GATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PRK01259 235 GAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
36-350 |
1.63e-149 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 423.61 E-value: 1.63e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV-QSGSGEINDNLMELLIMINACKIASA 114
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 115 SRVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEN 194
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFK----SREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 195 IpeWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERK-KANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 273
Cdd:TIGR01251 157 I--LDNPVVVSPDAGGVERAKKVADALGCPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILK 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665410166 274 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHmrdCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:TIGR01251 235 SAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEKH---KPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
36-156 |
1.85e-67 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 207.66 E-value: 1.85e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASAS 115
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 665410166 116 RVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAG 156
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDK----PREPITAKLVADLLEAAG 117
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
183-310 |
4.30e-25 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 98.24 E-value: 4.30e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 183 AEPAVLKWIKENIpeWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASM------VLVGDVKDKIAILVD 256
Cdd:cd06223 1 AGRLLAEEIREDL--LEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVD 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 665410166 257 DMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAisRINNACFEAVVVTNT 310
Cdd:cd06223 79 DVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PrsA |
COG0462 |
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ... |
33-350 |
1.22e-169 |
|
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis
Pssm-ID: 440230 [Multi-domain] Cd Length: 311 Bit Score: 474.55 E-value: 1.22e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 33 MPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIA 112
Cdd:COG0462 1 MKDLKIFSGNANPELAEEIAEYLGVPLGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 113 SASRVTAVIPCFPYARQDKKDKAnaqsRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIK 192
Cdd:COG0462 81 SARRITAVIPYYGYARQDRKFRP----REPITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 193 ENipEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRL 272
Cdd:COG0462 157 SK--DLEDLVVVSPDVGGVKRARAFAKRLGAPLAIIDKRRPGANEVEVMNIIGDVEGKTCIIVDDMIDTGGTLVEAAEAL 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665410166 273 VEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRdCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:COG0462 235 KEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEKR-CDKIKVLSVAPLLAEAIRRIHEGESVSSLFD 311
|
|
| PRK01259 |
PRK01259 |
ribose-phosphate diphosphokinase; |
36-349 |
1.98e-158 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 234929 [Multi-domain] Cd Length: 309 Bit Score: 446.10 E-value: 1.98e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASAS 115
Cdd:PRK01259 1 MKLFAGNANPELAEKIAKYLGIPLGKASVGRFSDGEISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 116 RVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENI 195
Cdd:PRK01259 81 RITAVIPYFGYARQDRKAR----SRVPITAKLVANLLETAGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQKN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 196 PEwkNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEA 275
Cdd:PRK01259 157 LE--NLVVVSPDVGGVVRARALAKRLDADLAIIDKRRPRANVSEVMNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKER 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665410166 276 GATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PRK01259 235 GAKSVYAYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLF 308
|
|
| ribP_PPkin |
TIGR01251 |
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ... |
36-350 |
1.63e-149 |
|
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 273523 [Multi-domain] Cd Length: 308 Bit Score: 423.61 E-value: 1.63e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIV-QSGSGEINDNLMELLIMINACKIASA 114
Cdd:TIGR01251 1 MKIFSGSSNQELAQKVAKNLGLPLGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 115 SRVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEN 194
Cdd:TIGR01251 81 KSITAVIPYYGYARQDKKFK----SREPISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 195 IpeWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERK-KANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 273
Cdd:TIGR01251 157 I--LDNPVVVSPDAGGVERAKKVADALGCPLAIIDKRRIsATNEVEVMNLVGDVEGKDVVIVDDIIDTGGTIAKAAEILK 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665410166 274 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHmrdCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:TIGR01251 235 SAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEKH---KPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
|
|
| PLN02369 |
PLN02369 |
ribose-phosphate pyrophosphokinase |
45-349 |
4.51e-111 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 215209 [Multi-domain] Cd Length: 302 Bit Score: 325.88 E-value: 4.51e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 45 PDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCF 124
Cdd:PLN02369 1 PALSQEIACYLGLELGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 125 PYARQDKKdkanAQSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWKNSIIV 204
Cdd:PLN02369 81 GYARADRK----TQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 205 SPDAGGAKRVTSIADRL-NVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAI 283
Cdd:PLN02369 157 SPDVGGVARARAFAKKLsDAPLAIVDKRRQGHNVAEVMNLIGDVKGKVAIMVDDMIDTAGTITKGAALLHQEGAREVYAC 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665410166 284 LTHGIFSGPAISRINNACFEAVVVTNTIPQDgHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PLN02369 237 ATHAVFSPPAIERLSSGLFQEVIVTNTIPVS-EKNYFPQLTVLSVANLLGETIWRVHDDCSVSSIF 301
|
|
| PRK04923 |
PRK04923 |
ribose-phosphate diphosphokinase; |
34-349 |
1.30e-107 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179893 [Multi-domain] Cd Length: 319 Bit Score: 317.64 E-value: 1.30e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 34 PNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIAS 113
Cdd:PRK04923 5 RNLLVFSGNANKPLAQSICKELGVRMGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 114 ASRVTAVIPCFPYARQDKKDKAnaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLK--WI 191
Cdd:PRK04923 85 AASVTAVIPYFGYSRQDRRMRS---SRVPITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLAdiWR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 192 KENIPewkNSIIVSPDAGGAKRVTSIADRL-NVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAAD 270
Cdd:PRK04923 162 AYGTD---NLIVVSPDVGGVVRARAVAKRLdDADLAIIDKRRPRANVATVMNIIGDVQGKTCVLVDDLVDTAGTLCAAAA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665410166 271 RLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PRK04923 239 ALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
|
|
| PRK02812 |
PRK02812 |
ribose-phosphate pyrophosphokinase; Provisional |
36-349 |
3.26e-107 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235072 [Multi-domain] Cd Length: 330 Bit Score: 317.07 E-value: 3.26e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASAS 115
Cdd:PRK02812 22 LRLFSGSSNPALAQEVARYLGMDLGPMIRKRFADGELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 116 RVTAVIPCFPYARQDKKdkanAQSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKE-N 194
Cdd:PRK02812 102 QITAVIPYYGYARADRK----TAGRESITAKLVANLITKAGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASkN 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 195 IPEwknSIIVSPDAGGAKRVTSIADRLN-VEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLV 273
Cdd:PRK02812 178 LED---IVVVSPDVGGVARARAFAKKLNdAPLAIIDKRRQAHNVAEVLNVIGDVKGKTAILVDDMIDTGGTICEGARLLR 254
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665410166 274 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIP--QDGHMrdcPKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PRK02812 255 KEGAKQVYACATHAVFSPPAIERLSSGLFEEVIVTNTIPvpEERRF---PQLKVLSVANMLGEAIWRIHEESSVSSMF 329
|
|
| PRK02269 |
PRK02269 |
ribose-phosphate diphosphokinase; |
35-349 |
4.08e-107 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 167353 [Multi-domain] Cd Length: 320 Bit Score: 316.35 E-value: 4.08e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 35 NIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASA 114
Cdd:PRK02269 5 DLKLFALSSNKELAEKVAQEIGIELGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 115 SRVTAVIPCFPYARQDKKdkanAQSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKEN 194
Cdd:PRK02269 85 ESINVVMPYYGYARQDRK----ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 195 IPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERK--KANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRL 272
Cdd:PRK02269 161 GLVGDDVVVVSPDHGGVTRARKLAQFLKTPIAIIDKRRSvdKMNTSEVMNIIGNVKGKKCILIDDMIDTAGTICHAADAL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665410166 273 VEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTI--PQDGHMRdcpKIQCIDVSMMFAEAVRRTHNGESVSYLF 349
Cdd:PRK02269 241 AEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIylPEERLID---KIEQISIADLLGEAIIRIHEKRPLSPLF 316
|
|
| PTZ00145 |
PTZ00145 |
phosphoribosylpyrophosphate synthetase; Provisional |
29-354 |
4.55e-104 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 240290 [Multi-domain] Cd Length: 439 Bit Score: 312.96 E-value: 4.55e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 29 IHSRMPNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINA 108
Cdd:PTZ00145 113 FEKKMENAILFSGSSNPLLSKNIADHLGTILGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMIST 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 109 CKIASASRVTAVIPCFPYARQDKKdkanAQSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFD--IPVDNLYAEPA 186
Cdd:PTZ00145 193 CRRASAKKITAVIPYYGYARQDRK----LSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGprVPVDNLEAQLI 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 187 VLKWIKENiPEWKnSIIVSPDAGGAKRVTSIADRLN------VEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMAD 260
Cdd:PTZ00145 269 GLDYFTKK-DLYK-PVIVSPDAGGVYRARKFQDGLNhrgisdCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMID 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 261 TCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTH 340
Cdd:PTZ00145 347 TSGTLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIH 426
|
330
....*....|....
gi 665410166 341 NGESVSYLFsNVPY 354
Cdd:PTZ00145 427 QKESLNDLF-NVKG 439
|
|
| PRK03092 |
PRK03092 |
ribose-phosphate diphosphokinase; |
47-353 |
6.12e-104 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 179535 [Multi-domain] Cd Length: 304 Bit Score: 307.64 E-value: 6.12e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 47 LAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRVTAVIPCFPY 126
Cdd:PRK03092 1 LAEEVAKELGVEVTPTTAYDFANGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 127 ARQDKKDKAnaqsRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPEwKNSIIVSP 206
Cdd:PRK03092 81 ARQDKKHRG----REPISARLVADLFKTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVVSP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 207 DAGGAKRVTSIADRL-NVEFALIHKER--KKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAI 283
Cdd:PRK03092 156 DAGRVRVAEQWADRLgGAPLAFIHKTRdpTVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVIIA 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 284 LTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRdCPKIQCIDVSMMFAEAVRRTHNGESVSYLFSNVP 353
Cdd:PRK03092 236 ATHGVLSGPAAERLKNCGAREVVVTDTLPIPEEKR-FDKLTVLSIAPLLARAIREVFEDGSVTSLFDGLA 304
|
|
| PRK02458 |
PRK02458 |
ribose-phosphate pyrophosphokinase; Provisional |
34-350 |
3.43e-92 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 235039 [Multi-domain] Cd Length: 323 Bit Score: 278.55 E-value: 3.43e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 34 PNIKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIAS 113
Cdd:PRK02458 8 KQIKLFSLNSNLEIAEKIAQAAGVPLGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 114 ASRVTAVIPCFPYARQDKkdkaNAQSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKE 193
Cdd:PRK02458 88 ANTVNVVLPYFGYARQDR----IAKPREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 194 NIPEWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVlVGDVKDKIAILVDDMADTCGTIVHAADRLV 273
Cdd:PRK02458 164 KGLSGSDVVVVSPKNSGIKRARSLAEYLDAPIAIIDYAQDDSEREEGYI-IGDVAGKKAILIDDILNTGKTFAEAAKIVE 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665410166 274 EAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIpqDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:PRK02458 243 REGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSV--ATKERVPKNVTYLSASELIADAIIRIHERKPLSPLFA 317
|
|
| PRK00553 |
PRK00553 |
ribose-phosphate pyrophosphokinase; Provisional |
38-350 |
2.67e-82 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 179062 [Multi-domain] Cd Length: 332 Bit Score: 253.69 E-value: 2.67e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 38 VFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASASRV 117
Cdd:PRK00553 12 IFSLSKAKKLVDSICRKLSMKPGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 118 TAVIPCFPYARQDKKDKAnaqsRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIPE 197
Cdd:PRK00553 92 TAILPYYGYARQDRKTAG----REPITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLELLGK 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 198 wKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGA 277
Cdd:PRK00553 168 -KDLVVVSPDYGGVKRARLIAESLELPLAIIDKRRPKHNVAESINVLGEVKNKNCLIVDDMIDTGGTVIAAAKLLKKQKA 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665410166 278 TKVYAILTHGIFSGPAISRINNACFEAVV----VTNTIPQDgHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:PRK00553 247 KKVCVMATHGLFNKNAIQLFDEAFKKKLIdklfVSNSIPQT-KFEKKPQFKVVDLAHLYEEVLLCYANGGSISAIYT 322
|
|
| Pribosyltran_N |
pfam13793 |
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ... |
36-156 |
1.85e-67 |
|
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.
Pssm-ID: 433483 [Multi-domain] Cd Length: 117 Bit Score: 207.66 E-value: 1.85e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 36 IKVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEINDNLMELLIMINACKIASAS 115
Cdd:pfam13793 1 LKIFSGNSNPELAEKIAKRLGIPLGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAK 80
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 665410166 116 RVTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAG 156
Cdd:pfam13793 81 RITAVIPYFGYARQDRKDK----PREPITAKLVADLLEAAG 117
|
|
| PRK00934 |
PRK00934 |
ribose-phosphate pyrophosphokinase; Provisional |
37-314 |
8.47e-63 |
|
ribose-phosphate pyrophosphokinase; Provisional
Pssm-ID: 234868 [Multi-domain] Cd Length: 285 Bit Score: 201.68 E-value: 8.47e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 37 KVFSGTSHPDLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSGEiNDNLMELLIMINACKIASASR 116
Cdd:PRK00934 1 MIIGGSASQLLASEVARLLNTELALVETKRFPDGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 117 VTAVIPCFPYARQDKKDKanaqSRAPISAKLVANMLSVAGaDHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENIp 196
Cdd:PRK00934 80 ITLVIPYLGYARQDKRFK----PGEPISARAIAKIISAYY-DRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGDKL- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 197 ewKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAG 276
Cdd:PRK00934 154 --DDPLVLAPDKGALELAKEAAEILGCEYDYLEKTRISPTEVEIAPKNLDVKGKDVLIVDDIISTGGTMATAIKILKEQG 231
|
250 260 270
....*....|....*....|....*....|....*...
gi 665410166 277 ATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQD 314
Cdd:PRK00934 232 AKKVYVACVHPVLVGDAILKLYNAGVDEIIVTDTLESE 269
|
|
| Pribosyl_synth |
pfam14572 |
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ... |
197-349 |
6.28e-47 |
|
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.
Pssm-ID: 434046 Cd Length: 184 Bit Score: 157.67 E-value: 6.28e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 197 EWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKA------------------------------NEVASMVLVGD 246
Cdd:pfam14572 1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAesdevdgrqspppyrsrtvsrslglpeiipKEKPPMTVVGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 247 VKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQDGHMRDCPKIQCI 326
Cdd:pfam14572 81 VGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKTI 160
|
170 180
....*....|....*....|...
gi 665410166 327 DVSMMFAEAVRRTHNGESVSYLF 349
Cdd:pfam14572 161 DISQLIAEAIRRIHNGESMSYLF 183
|
|
| PRK07199 |
PRK07199 |
ribose-phosphate diphosphokinase; |
46-338 |
4.99e-43 |
|
ribose-phosphate diphosphokinase;
Pssm-ID: 235960 [Multi-domain] Cd Length: 301 Bit Score: 150.86 E-value: 4.99e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 46 DLAQRIVDRLGIDLGKVVTKKFSNLETCVEIGESVRGEDVYIVQSGSgEINDNLMELLIMINACKIASASRVTAVIPCFP 125
Cdd:PRK07199 13 AAAGRLAAALGVEVGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLD-RPDEKLLPLLFAAEAARELGARRVGLVAPYLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 126 YARQDKKdkanAQSRAPISAKLVANMLSvAGADHIITMD--LH-ASQIQGFFDIPVDNLYAEPAVLKWIKENIPEWknsI 202
Cdd:PRK07199 92 YMRQDIA----FHPGEAISQRHFARLLS-GSFDRLVTVDphLHrYPSLSEVYPIPAVVLSAAPAIAAWIRAHVPRP---L 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 203 IVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVAsmVLVGDV---KDKIAILVDDMADTCGTIVHAADRLVEAGATK 279
Cdd:PRK07199 164 LIGPDEESEQWVAAVAERAGAPHAVLRKTRHGDRDVE--ISLPDAapwAGRTPVLVDDIVSTGRTLIEAARQLRAAGAAS 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 665410166 280 VYAILTHGIFSGPAISRINNACFEAVVVTNTIPqdgHMRDcpkiqCIDVSMMFAEAVRR 338
Cdd:PRK07199 242 PDCVVVHALFAGDAYSALAAAGIARVVSTDTVP---HPSN-----AISLAPLLAEALRR 292
|
|
| PRK06827 |
PRK06827 |
phosphoribosylpyrophosphate synthetase; Provisional |
61-351 |
1.31e-39 |
|
phosphoribosylpyrophosphate synthetase; Provisional
Pssm-ID: 180714 [Multi-domain] Cd Length: 382 Bit Score: 143.94 E-value: 1.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 61 KVVTKKFSNLETCVEIGESVRGEDVYIVQ---------SGSGE-----INDNLMELLIMINACKiASASRVTAVIPCFPY 126
Cdd:PRK06827 56 PAKFIRFSNGEAKGEILESVRGKDIYILQdvgnysvtyNMFGEknhmsPDDHFQDLKRTIDAIR-GKARRITVIMPFLYE 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 127 ARQDKKDkanaqSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDI-PVDNLYAEPAVLKWIKENIPE----WKNS 201
Cdd:PRK06827 135 SRQHKRK-----GRESLDCALALQELEELGVDNIITFDAHDPRIENAIPLmGFENLYPSYQIIKALLKNEKDleidKDHL 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 202 IIVSPDAGGAKRVTSIADRLNVEFALIHKERK-------KANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVE 274
Cdd:PRK06827 210 MVISPDTGAMDRAKYYASVLGVDLGLFYKRRDysrvvngRNPIVAHEFLGRDVEGKDVLIVDDMIASGGSMIDAAKELKS 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 275 AGATKVYAILTHGIFSGpAISRINNA----CFEAVVVTNTIPQDGHMRDCPKIQCIDVSMMFAEAVRRTHNGESVSYLFS 350
Cdd:PRK06827 290 RGAKKIIVAATFGFFTN-GLEKFDKAyeegYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARIIDALNHDVSLSKLLD 368
|
.
gi 665410166 351 N 351
Cdd:PRK06827 369 P 369
|
|
| PRTases_typeI |
cd06223 |
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The ... |
183-310 |
4.30e-25 |
|
Phosphoribosyl transferase (PRT)-type I domain; Phosphoribosyl transferase (PRT) domain. The type I PRTases are identified by a conserved PRPP binding motif which features two adjacent acidic residues surrounded by one or more hydrophobic residue. PRTases catalyze the displacement of the alpha-1'-pyrophosphate of 5-phosphoribosyl-alpha1-pyrophosphate (PRPP) by a nitrogen-containing nucleophile. The reaction products are an alpha-1 substituted ribose-5'-phosphate and a free pyrophosphate (PP). PRPP, an activated form of ribose-5-phosphate, is a key metabolite connecting nucleotide synthesis and salvage pathways. The type I PRTase family includes a range of diverse phosphoribosyl transferase enzymes and regulatory proteins of the nucleotide synthesis and salvage pathways, including adenine phosphoribosyltransferase EC:2.4.2.7., hypoxanthine-guanine-xanthine phosphoribosyltransferase, hypoxanthine phosphoribosyltransferase EC:2.4.2.8., ribose-phosphate pyrophosphokinase EC:2.7.6.1., amidophosphoribosyltransferase EC:2.4.2.14., orotate phosphoribosyltransferase EC:2.4.2.10., uracil phosphoribosyltransferase EC:2.4.2.9., and xanthine-guanine phosphoribosyltransferase EC:2.4.2.22.
Pssm-ID: 206754 [Multi-domain] Cd Length: 130 Bit Score: 98.24 E-value: 4.30e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 183 AEPAVLKWIKENIpeWKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASM------VLVGDVKDKIAILVD 256
Cdd:cd06223 1 AGRLLAEEIREDL--LEPDVVVGILRGGLPLAAALARALGLPLAFIRKERKGPGRTPSEpyglelPLGGDVKGKRVLLVD 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 665410166 257 DMADTCGTIVHAADRLVEAGATKVYAILTHGIFSGPAisRINNACFEAVVVTNT 310
Cdd:cd06223 79 DVIATGGTLLAAIELLKEAGAKVVGVAVLLDKPEGGA--RELASPGDPVYSLFT 130
|
|
| PLN02297 |
PLN02297 |
ribose-phosphate pyrophosphokinase |
46-313 |
9.12e-13 |
|
ribose-phosphate pyrophosphokinase
Pssm-ID: 177934 [Multi-domain] Cd Length: 326 Bit Score: 68.18 E-value: 9.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 46 DLAQRIVDRLG-IDLGKVVTKKFS----NLEtcVEIGESVRGEDVYIVQSGSGeiNDNLMELLIMINACKIASASRVTAV 120
Cdd:PLN02297 27 ELARKIAAESDaIELGSINWRKFPdgfpNLF--INNAHGIRGQHVAFLASFSS--PAVIFEQLSVIYALPKLFVASFTLV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 121 IPCFPYARQDKKDKANAQSRAPISAKLVANM-LSVAGADHIITMDLHASQIQGFFDIPVDNLYAE--PAVLKWIKEnIPE 197
Cdd:PLN02297 103 LPFFPTGTSERVEREGDVATAFTLARILSNIpISRGGPTSLVIFDIHALQERFYFGDNVLPCFESgiPLLKKRLQQ-LPD 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 198 WKNSIIVSPDAGGAKRVTSIADrlNVEFALIHKERKkaNEVASMVLV-GDVKDKIAILVDDMADTCGTIVHAADRLVEAG 276
Cdd:PLN02297 182 SDNIVIAFPDDGAWKRFHKQFE--HFPMVVCTKVRE--GDKRIVRIKeGNPAGRHVVIVDDLVQSGGTLIECQKVLAAHG 257
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 665410166 277 ATKVYAILTHGIFSGPAISRINN------ACFEAVVVTNTIPQ 313
Cdd:PLN02297 258 AAKVSAYVTHGVFPNESWERFTHdnggpeAGFAYFWITDSCPQ 300
|
|
| Pribosyltran |
pfam00156 |
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl ... |
177-280 |
1.59e-11 |
|
Phosphoribosyl transferase domain; This family includes a range of diverse phosphoribosyl transferase enzymes. This family includes: Adenine phosphoribosyl-transferase EC:2.4.2.7. Hypoxanthine-guanine-xanthine phosphoribosyl-transferase. Hypoxanthine phosphoribosyl-transferase EC:2.4.2.8. Ribose-phosphate pyrophosphokinase i EC:2.7.6.1. Amidophosphoribosyltransferase EC:2.4.2.14. Orotate phosphoribosyl-transferase EC:2.4.2.10. Uracil phosphoribosyl-transferase EC:2.4.2.9. Xanthine-guanine phosphoribosyl-transferase EC:2.4.2.22. In Arabidopsis, At the very N-terminus of this domain is the P-Loop NTPase domain.
Pssm-ID: 425489 [Multi-domain] Cd Length: 150 Bit Score: 61.61 E-value: 1.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 177 PVDNLYAEPAVLKWIKENIPE------WKNSIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVASMVLV---GDV 247
Cdd:pfam00156 1 SVDEILDNPAILKAVARLAAQinedygGKPDVVVGILRGGLPFAGILARRLDVPLAFVRKVSYNPDTSEVMKTSsalPDL 80
|
90 100 110
....*....|....*....|....*....|...
gi 665410166 248 KDKIAILVDDMADTCGTIVHAADRLVEAGATKV 280
Cdd:pfam00156 81 KGKTVLIVDDILDTGGTLLKVLELLKNVGPKEV 113
|
|
| PRK07322 |
PRK07322 |
adenine phosphoribosyltransferase; Provisional |
202-287 |
1.54e-03 |
|
adenine phosphoribosyltransferase; Provisional
Pssm-ID: 180928 Cd Length: 178 Bit Score: 38.81 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665410166 202 IIVSPDAGGAKRVTSIADRLNVEFALIHKERKK------ANEVASM------VLVGDVKD------KIAILVDDMADTCG 263
Cdd:PRK07322 55 VLVTPETKGIPLAHALSRRLGKPYVVARKSRKPymqdpiIQEVVSIttgkpqLLVLDGADaeklkgKRVAIVDDVVSTGG 134
|
90 100
....*....|....*....|....*..
gi 665410166 264 TIvHAADRLVE-AGAT--KVYAILTHG 287
Cdd:PRK07322 135 TL-TALERLVErAGGQvvAKAAIFAEG 160
|
|
| Hpt1 |
COG2236 |
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine ... |
217-280 |
4.04e-03 |
|
Hypoxanthine phosphoribosyltransferase [Coenzyme transport and metabolism]; Hypoxanthine phosphoribosyltransferase is part of the Pathway/BioSystem: Purine salvage
Pssm-ID: 441837 [Multi-domain] Cd Length: 153 Bit Score: 37.52 E-value: 4.04e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665410166 217 IADRLNV-EFALI------HKERKKANEVASMVLVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKV 280
Cdd:COG2236 49 LADALGVpDLASIrvssytGTAKRLEEPVVKGPLDEDLAGKRVLIVDDVADTGRTLEAVRDLLKEAGPAEV 119
|
|
| PyrE |
COG0461 |
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate ... |
214-287 |
5.64e-03 |
|
Orotate phosphoribosyltransferase [Nucleotide transport and metabolism]; Orotate phosphoribosyltransferase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440229 Cd Length: 201 Bit Score: 37.44 E-value: 5.64e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665410166 214 VTSIADRLNVEFALIHKERKKANEVASmvLVGDVK--DKIAIlVDDMADTCGTIVHAADRLVEAGAT--KVYAILTHG 287
Cdd:COG0461 78 AAAVARALGLPAIFVRKEAKDHGTGGQ--IEGGLLpgERVLV-VEDVITTGGSVLEAVEALREAGAEvvGVAVIVDRE 152
|
|
| upp |
PRK00129 |
uracil phosphoribosyltransferase; Reviewed |
243-283 |
6.85e-03 |
|
uracil phosphoribosyltransferase; Reviewed
Pssm-ID: 234653 Cd Length: 209 Bit Score: 37.38 E-value: 6.85e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 665410166 243 LVGDVKDKIAILVDDMADTCGTIVHAADRLVEAGATKVYAI 283
Cdd:PRK00129 118 LPEDIDERTVIVVDPMLATGGSAIAAIDLLKKRGAKNIKVL 158
|
|
| |
