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Conserved domains on  [gi|922581730|ref|NP_001300374|]
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SAP domain-containing protein [Caenorhabditis elegans]

Protein Classification

SAP domain-containing protein( domain architecture ID 10488483)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

CATH:  1.10.720.30
Gene Ontology:  GO:0003676|GO:0003700
PubMed:  10694879
SCOP:  4002795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 336-364 1.96e-04

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


:

Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 39.69  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*....
gi 922581730   336 TDLRSACKKRSLPHTGPKPRLCERLRGHE 364
Cdd:pfam02037    7 AELKEELRKRGLPTSGKKAELIERLQEYL 35
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 75-223 8.61e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.49  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581730    75 QSSQVNQCDYNQNMSEQSEQPILRPSRMESTNQSHQNIDSMYHIDQPQQvvfqanLQNRSNRVMQQTPNNSSNHQNHLSL 154
Cdd:pfam09770  217 APAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI------LQRPQSPQPDPAQPSIQPQAQQFHQ 290

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922581730   155 KQPHLSMNSTQLqsgFQTGNRMMPSFQVNPTTQDQVPHLSHMDQPPPTQHSMNSISQSQQHPSQLSQLS 223
Cdd:pfam09770  291 QPPPVPVQPTQI---LQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQQLAQLS 356
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 336-364 1.96e-04

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 39.69  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*....
gi 922581730   336 TDLRSACKKRSLPHTGPKPRLCERLRGHE 364
Cdd:pfam02037    7 AELKEELRKRGLPTSGKKAELIERLQEYL 35
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 75-223 8.61e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.49  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581730    75 QSSQVNQCDYNQNMSEQSEQPILRPSRMESTNQSHQNIDSMYHIDQPQQvvfqanLQNRSNRVMQQTPNNSSNHQNHLSL 154
Cdd:pfam09770  217 APAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI------LQRPQSPQPDPAQPSIQPQAQQFHQ 290

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922581730   155 KQPHLSMNSTQLqsgFQTGNRMMPSFQVNPTTQDQVPHLSHMDQPPPTQHSMNSISQSQQHPSQLSQLS 223
Cdd:pfam09770  291 QPPPVPVQPTQI---LQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQQLAQLS 356
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
 336-364 1.96e-04

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 39.69  E-value: 1.96e-04
                           10        20
                   ....*....|....*....|....*....
gi 922581730   336 TDLRSACKKRSLPHTGPKPRLCERLRGHE 364
Cdd:pfam02037    7 AELKEELRKRGLPTSGKKAELIERLQEYL 35
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 75-223 8.61e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.49  E-value: 8.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922581730    75 QSSQVNQCDYNQNMSEQSEQPILRPSRMESTNQSHQNIDSMYHIDQPQQvvfqanLQNRSNRVMQQTPNNSSNHQNHLSL 154
Cdd:pfam09770  217 APAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTI------LQRPQSPQPDPAQPSIQPQAQQFHQ 290

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 922581730   155 KQPHLSMNSTQLqsgFQTGNRMMPSFQVNPTTQDQVPHLSHMDQPPPTQHSMNSISQSQQHPSQLSQLS 223
Cdd:pfam09770  291 QPPPVPVQPTQI---LQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQQLAQLS 356
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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