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Conserved domains on  [gi|939619907|ref|NP_001303371|]
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pre-mRNA processing factor 6, isoform B [Drosophila melanogaster]

Protein Classification

pre-mRNA-processing factor 6 family protein( domain architecture ID 13720877)

pre-mRNA-processing factor 6 (PRPF6) family protein similar to human PRPF6 that is involved in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 22-173 2.21e-58

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


:

Pssm-ID: 461908  Cd Length: 109  Bit Score: 195.05  E-value: 2.21e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907   22 APLGYVAGVGRGATGFTTrsdigpardandvsddrhappatkrkkkdeeeeededlndsnyDEFSGYSGSLFSKDPYDKD 101
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT-------------------------------------------DEFEGYDGGLFAGGPYDKD 37

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 939619907  102 DEEADAIYDSIDKRMDEKRKEYRDRRLREDLERYRQERPKIQQQFSDLKRSLASVTSEEWSTIPEVGDSRNR 173
Cdd:pfam06424  38 DEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 610-861 2.10e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 89.40  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 610 MAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLL 688
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDrAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 689 EEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAV 768
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 769 LWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAIFMETKPQRKTKSVDALKKC---EHDPHVLLAVSKLFWSEH 845
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAlelDPSDDLLLALADLLERKE 259

                        250
                 ....*....|....*.
gi 939619907 846 KFSKCRDWFNRTVKID 861
Cdd:COG2956  260 GLEAALALLERQLRRH 275
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 236-800 1.80e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 74.73  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  236 ARNTLMNVKLSQVSDSVTGQTVVDPKGYLTDLQSMIPTYGGdINDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKV 315
Cdd:TIGR02917  97 ARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALRGLAYLG-LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRF 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  316 QMARNLIMRGCEMNIQSEDLWLEAARLQ----PPDTAKAVIAQAARHIPTS-------VRIWIKAADLE-SETKAKrrvf 383
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKAIALRPNNiavllalATILIEAGEFEeAEKHAD---- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  384 rKALEHIPNS--VRLWKAAVELENPD--DARILLSRAVECCNTSVELWL----ALARLETYENARKVLNKARENIPTDRQ 455
Cdd:TIGR02917 252 -ALLKKAPNSplAHYLKALVDFQKKNyeDARETLQDALKSAPEYLPALLlagaSEYQLGNLEQAYQYLNQILKYAPNSHQ 330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  456 IWTTAAKLEEANGN----IHMVEKIIDRSLTS---LTVNGVEINRDQWFQEAIEA-EKSGAVNCCQSIVKAVIGIGVEEE 527
Cdd:TIGR02917 331 ARRLLASIQLRLGRvdeaIATLSPALGLDPDDpaaLSLLGEAYLALGDFEKAAEYlAKATELDPENAAARTQLGISKLSQ 410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  528 DRKQTWIDDAEFCA------------------KENAFECARAVYAHALQIFPSKKSIW--LRAAYFEKNH--GTRESLEA 585
Cdd:TIGR02917 411 GDPSEAIADLETAAqldpelgradlllilsylRSGQFDKALAAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEK 490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  586 LLQRAVAHCPKSEILWLMGAKskwmAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT- 664
Cdd:TIGR02917 491 ALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQe 566

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  665 --PRVMMKSARLEwaLEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:TIGR02917 567 iePALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADA 644

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 939619907  743 EERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNA 800
Cdd:TIGR02917 645 YAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKA 702
 
Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 22-173 2.21e-58

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


Pssm-ID: 461908  Cd Length: 109  Bit Score: 195.05  E-value: 2.21e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907   22 APLGYVAGVGRGATGFTTrsdigpardandvsddrhappatkrkkkdeeeeededlndsnyDEFSGYSGSLFSKDPYDKD 101
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT-------------------------------------------DEFEGYDGGLFAGGPYDKD 37

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 939619907  102 DEEADAIYDSIDKRMDEKRKEYRDRRLREDLERYRQERPKIQQQFSDLKRSLASVTSEEWSTIPEVGDSRNR 173
Cdd:pfam06424  38 DEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 610-861 2.10e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 89.40  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 610 MAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLL 688
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDrAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 689 EEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAV 768
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 769 LWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAIFMETKPQRKTKSVDALKKC---EHDPHVLLAVSKLFWSEH 845
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAlelDPSDDLLLALADLLERKE 259

                        250
                 ....*....|....*.
gi 939619907 846 KFSKCRDWFNRTVKID 861
Cdd:COG2956  260 GLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 236-800 1.80e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 74.73  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  236 ARNTLMNVKLSQVSDSVTGQTVVDPKGYLTDLQSMIPTYGGdINDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKV 315
Cdd:TIGR02917  97 ARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALRGLAYLG-LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRF 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  316 QMARNLIMRGCEMNIQSEDLWLEAARLQ----PPDTAKAVIAQAARHIPTS-------VRIWIKAADLE-SETKAKrrvf 383
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKAIALRPNNiavllalATILIEAGEFEeAEKHAD---- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  384 rKALEHIPNS--VRLWKAAVELENPD--DARILLSRAVECCNTSVELWL----ALARLETYENARKVLNKARENIPTDRQ 455
Cdd:TIGR02917 252 -ALLKKAPNSplAHYLKALVDFQKKNyeDARETLQDALKSAPEYLPALLlagaSEYQLGNLEQAYQYLNQILKYAPNSHQ 330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  456 IWTTAAKLEEANGN----IHMVEKIIDRSLTS---LTVNGVEINRDQWFQEAIEA-EKSGAVNCCQSIVKAVIGIGVEEE 527
Cdd:TIGR02917 331 ARRLLASIQLRLGRvdeaIATLSPALGLDPDDpaaLSLLGEAYLALGDFEKAAEYlAKATELDPENAAARTQLGISKLSQ 410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  528 DRKQTWIDDAEFCA------------------KENAFECARAVYAHALQIFPSKKSIW--LRAAYFEKNH--GTRESLEA 585
Cdd:TIGR02917 411 GDPSEAIADLETAAqldpelgradlllilsylRSGQFDKALAAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEK 490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  586 LLQRAVAHCPKSEILWLMGAKskwmAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT- 664
Cdd:TIGR02917 491 ALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQe 566

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  665 --PRVMMKSARLEwaLEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:TIGR02917 567 iePALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADA 644

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 939619907  743 EERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNA 800
Cdd:TIGR02917 645 YAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKA 702
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 404-693 1.63e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 1.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 404 ENPDDARILLSRAVECCNTSVELWLALARLET----YENARKVLNKARENIPTDRQIWTTAAKLEEANGNihmvekiidr 479
Cdd:COG2956   22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgeYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL---------- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 480 sltsltvngveinrdqwFQEAIEAeksgavncCQSIVKavigigvEEEDRKQTWIDDAEFCAKENAFECARAVYAHALQI 559
Cdd:COG2956   92 -----------------LDRAEEL--------LEKLLE-------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 560 FPSKKSIWLRAA--YFEKNHgtRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLA 637
Cdd:COG2956  140 GPENAHAYCELAelYLEQGD--YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPR 217

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 939619907 638 AVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVE 693
Cdd:COG2956  218 LAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLR 273
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 672-732 2.87e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 45.79  E-value: 2.87e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 939619907  672 ARLEWALEKFDEALRLLEEAVEVFPDFPK---LWMMKGQIEEQQRRTDDAAATYTLGLKKCPTS 732
Cdd:pfam13432   4 ARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 537-898 3.20e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 3.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  537 AEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPA 616
Cdd:TIGR02917 166 AQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  617 ARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT--PRVMMKSArLEWALEKFDEALRLLEEAVEV 694
Cdd:TIGR02917 246 AEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEylPALLLAGA-SEYQLGNLEQAYQYLNQILKY 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  695 FPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAI 774
Cdd:TIGR02917 325 APNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  775 RVELRAGLKEIASTMMARALQ---ECPNAGELWAEAIFMETKPQRKTKSVDALKKCEHD---PHVLLAVSKLfwSEHKFS 848
Cdd:TIGR02917 405 ISKLSQGDPSEAIADLETAAQldpELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDnasLHNLLGAIYL--GKGDLA 482

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 939619907  849 KCRDWFNRTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTH 898
Cdd:TIGR02917 483 KAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKN 532
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 567-763 6.24e-06

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 49.42  E-value: 6.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 567 WLRAAyfeknhGTRESLEAL----LQRAVAH--CpksEIlwlmgAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVK 640
Cdd:PRK11788 157 WQKAI------DVAERLEKLggdsLRVEIAHfyC---EL-----AQQALARGDLDAARALLKKALAADPQCVRASILLGD 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 641 LESENSEYERARRLLAKARGSAP--TPRV---MMKSARlewALEKFDEALRLLEEAVEVFPdFPKLWMMKGQIEEQQRRT 715
Cdd:PRK11788 223 LALAQGDYAAAIEALERVEEQDPeyLSEVlpkLMECYQ---ALGDEAEGLEFLRRALEEYP-GADLLLALAQLLEEQEGP 298

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 939619907 716 DDAAATYTLGLKKCPTS------IPLWILSANLEERKGVLTKARSILERgRLRN 763
Cdd:PRK11788 299 EAAQALLREQLRRHPSLrgfhrlLDYHLAEAEEGRAKESLLLLRDLVGE-QLKR 351
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 434-466 2.55e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.37  E-value: 2.55e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 939619907   434 ETYENARKVLNKARENIPTDRQIWTTAAKLEEA 466
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 368-478 4.91e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 4.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 368 KAADL--ESETKAKRRVFRKALEHIPNSVRLWKAA----VELENPDDARILLSRAVECC-NTSVELWLALARLETYENAR 440
Cdd:cd24142    6 KAEELldQGNFELALKFLQRALELEPNNVEALELLgeilLELGDVEEAREVLLRAIELDpDGGYEKYLYLGQLSGGEEAL 85

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 939619907 441 KVLNKARENIptDRQIWTTAAKLEEANGNI-HMVEKIID 478
Cdd:cd24142   86 QYYEKGIEIL--EEELQALQAASAEAEEEAeELKRKLSS 122
 
Name Accession Description Interval E-value
PRP1_N pfam06424
PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 ...
 22-173 2.21e-58

PRP1 splicing factor, N-terminal; This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.


Pssm-ID: 461908  Cd Length: 109  Bit Score: 195.05  E-value: 2.21e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907   22 APLGYVAGVGRGATGFTTrsdigpardandvsddrhappatkrkkkdeeeeededlndsnyDEFSGYSGSLFSKDPYDKD 101
Cdd:pfam06424   1 APPGYVAGLGRGATGFTT-------------------------------------------DEFEGYDGGLFAGGPYDKD 37

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 939619907  102 DEEADAIYDSIDKRMDEKRKEYRDRRLREDLERYRQERPKIQQQFSDLKRSLASVTSEEWSTIPEVGDSRNR 173
Cdd:pfam06424  38 DEEADRIYEAIDERMDERRKKRREAREKEELEKYRAERPKIQQQFADLKRGLATVSEEEWANIPEVGDLTRK 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 610-861 2.10e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 89.40  E-value: 2.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 610 MAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLL 688
Cdd:COG2956   20 LNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDrAEALLELAQDYLKAGLLDRAEELL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 689 EEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAV 768
Cdd:COG2956  100 EKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 769 LWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAIFMETKPQRKTKSVDALKKC---EHDPHVLLAVSKLFWSEH 845
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAlelDPSDDLLLALADLLERKE 259

                        250
                 ....*....|....*.
gi 939619907 846 KFSKCRDWFNRTVKID 861
Cdd:COG2956  260 GLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 236-800 1.80e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 74.73  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  236 ARNTLMNVKLSQVSDSVTGQTVVDPKGYLTDLQSMIPTYGGdINDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKV 315
Cdd:TIGR02917  97 ARAYLLQGKFQQVLDELPGKTLLDDEGAAELLALRGLAYLG-LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRF 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  316 QMARNLIMRGCEMNIQSEDLWLEAARLQ----PPDTAKAVIAQAARHIPTS-------VRIWIKAADLE-SETKAKrrvf 383
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLlslgNIELALAAYRKAIALRPNNiavllalATILIEAGEFEeAEKHAD---- 251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  384 rKALEHIPNS--VRLWKAAVELENPD--DARILLSRAVECCNTSVELWL----ALARLETYENARKVLNKARENIPTDRQ 455
Cdd:TIGR02917 252 -ALLKKAPNSplAHYLKALVDFQKKNyeDARETLQDALKSAPEYLPALLlagaSEYQLGNLEQAYQYLNQILKYAPNSHQ 330

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  456 IWTTAAKLEEANGN----IHMVEKIIDRSLTS---LTVNGVEINRDQWFQEAIEA-EKSGAVNCCQSIVKAVIGIGVEEE 527
Cdd:TIGR02917 331 ARRLLASIQLRLGRvdeaIATLSPALGLDPDDpaaLSLLGEAYLALGDFEKAAEYlAKATELDPENAAARTQLGISKLSQ 410

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  528 DRKQTWIDDAEFCA------------------KENAFECARAVYAHALQIFPSKKSIW--LRAAYFEKNH--GTRESLEA 585
Cdd:TIGR02917 411 GDPSEAIADLETAAqldpelgradlllilsylRSGQFDKALAAAKKLEKKQPDNASLHnlLGAIYLGKGDlaKAREAFEK 490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  586 LLQRAVAHCPKSEILWLMGAKskwmAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT- 664
Cdd:TIGR02917 491 ALSIEPDFFPAAANLARIDIQ----EGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQe 566

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  665 --PRVMMKSARLEwaLEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:TIGR02917 567 iePALALAQYYLG--KGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADA 644

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 939619907  743 EERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNA 800
Cdd:TIGR02917 645 YAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKA 702
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 666-799 1.59e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.60  E-value: 1.59e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 666 RVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEER 745
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 939619907 746 KGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPN 799
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 404-693 1.63e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.99  E-value: 1.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 404 ENPDDARILLSRAVECCNTSVELWLALARLET----YENARKVLNKARENIPTDRQIWTTAAKLEEANGNihmvekiidr 479
Cdd:COG2956   22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRrrgeYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL---------- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 480 sltsltvngveinrdqwFQEAIEAeksgavncCQSIVKavigigvEEEDRKQTWIDDAEFCAKENAFECARAVYAHALQI 559
Cdd:COG2956   92 -----------------LDRAEEL--------LEKLLE-------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 560 FPSKKSIWLRAA--YFEKNHgtRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLA 637
Cdd:COG2956  140 GPENAHAYCELAelYLEQGD--YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPR 217

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 939619907 638 AVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVE 693
Cdd:COG2956  218 LAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 702-898 8.40e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 8.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 702 WMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAG 781
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 782 LKEIASTMMARALQECPNAGELWAE--AIFMETKpqRKTKSVDALKKCEH----DPHVLLAVSKLFWSEHKFSKCRDWFN 855
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLlaEIYEQEG--DWEKAIEVLERLLKlgpeNAHAYCELAELYLEQGDYDEAIEALE 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 939619907 856 RTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTH 898
Cdd:COG2956  169 KALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDY 211
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 621-744 5.63e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 60.79  E-value: 5.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 621 LSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAP-TPRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFP 699
Cdd:COG4235    6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPdNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 939619907 700 KLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEE 744
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 531-805 2.65e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.24  E-value: 2.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 531 QTWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAyfeknhgtresLEALLQRAVAHCPKSEILWlmgakskwM 610
Cdd:COG3914    2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALG-----------LALLLLAALAEAAAAALLA--------L 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 611 AGDVPAARGILSLAFQANPNSEDIWLAavklesENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLE 689
Cdd:COG3914   63 AAGEAAAAAAALLLLAALLELAALLLQ------ALGRYEEALALYRRALALNPDnAEALFNLGNLLLALGRLEEALAALR 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 690 EAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVL 769
Cdd:COG3914  137 RALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 939619907 770 WLEAIRVELRAGLKEIASTmMARALQECPNAGELWA 805
Cdd:COG3914  217 HSNLLFALRQACDWEVYDR-FEELLAALARGPSELS 251
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 279-446 5.64e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 5.64e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 279 NDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAARLQP----PDTAKAVIAQ 354
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLeqgdYDEAIEALEK 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 355 AARHIPTSVRIWIKAADLESETKAKR---RVFRKALEHIPNSV----RLWKAAVELENPDDARILLSRAVEcCNTSVELW 427
Cdd:COG2956  170 ALKLDPDCARALLLLAELYLEQGDYEeaiAALERALEQDPDYLpalpRLAELYEKLGDPEEALELLRKALE-LDPSDDLL 248

                        170       180
                 ....*....|....*....|...
gi 939619907 428 LALARL----ETYENARKVLNKA 446
Cdd:COG2956  249 LALADLlerkEGLEAALALLERQ 271
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 567-698 3.92e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.97  E-value: 3.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 567 WLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENS 646
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 939619907 647 EYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDF 698
Cdd:COG4783   87 DYDEALALLEKALKLDPEhPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 616-809 5.89e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.01  E-value: 5.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 616 AARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAptprvmmksARLEWALEKFDEALRLLEEAVEVF 695
Cdd:COG3914   38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA---------ALLLQALGRYEEALALYRRALALN 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 696 PDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAIR 775
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGN 188

                        170       180       190
                 ....*....|....*....|....*....|....
gi 939619907 776 VELRAGLKEIASTMMARALQECPNAGELWAEAIF 809
Cdd:COG3914  189 ALQDLGRLEEAIAAYRRALELDPDNADAHSNLLF 222
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
626-796 6.19e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.71  E-value: 6.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 626 QANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMM 704
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDdAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 705 KGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKE 784
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|..
gi 939619907 785 IASTMMARALQE 796
Cdd:COG0457  162 EALELLEKLEAA 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
584-786 1.02e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 584 EALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAP 663
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDP 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 664 T-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:COG0457  108 DdAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAA 187

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 939619907 743 EERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIA 786
Cdd:COG0457  188 LALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
672-826 2.06e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.17  E-value: 2.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 672 ARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTK 751
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEE 94

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 939619907 752 ARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAIFMETKPQRKTKSVDALKK 826
Cdd:COG0457   95 ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEK 169
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 279-469 2.42e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 2.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 279 NDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAARL----QPPDTAKAVIAQ 354
Cdd:COG2956   22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDylkaGLLDRAEELLEK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 355 AARHIPTSVRIWIKAADL---ESETKAKRRVFRKALEHIPNSVRLW----KAAVELENPDDARILLSRAVECCNTSVELW 427
Cdd:COG2956  102 LLELDPDDAEALRLLAEIyeqEGDWEKAIEVLERLLKLGPENAHAYcelaELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 939619907 428 LALARLET----YENARKVLNKARENIPTDRQIWTTAAKLEEANGN 469
Cdd:COG2956  182 LLLAELYLeqgdYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
612-808 5.82e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.63  E-value: 5.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 612 GDVPAARGILSLAFQANPNSEDIW--LAAVKLESENseYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLL 688
Cdd:COG0457   22 GRYEEAIEDYEKALELDPDDAEALynLGLAYLRLGR--YEEALADYEQALELDPDdAEALNNLGLALQALGRYEEALEDY 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 689 EEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAV 768
Cdd:COG0457  100 DKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALL 179

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 939619907 769 LWLEAIRVELRAGLKEIASTMMARALQECPNAGELWAEAI 808
Cdd:COG0457  180 AAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAAL 219
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 583-710 1.50e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 1.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 583 LEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSA 662
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 939619907 663 PT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEE 710
Cdd:COG4235   82 PDnPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 531-663 2.52e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.58  E-value: 2.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 531 QTWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWM 610
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 939619907 611 AGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAP 663
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 615-764 5.44e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 5.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 615 PAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWAL---EKFDEALRLLEEA 691
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYnklGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 939619907 692 VEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNP 764
Cdd:COG5010   81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 683-799 1.57e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.08  E-value: 1.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 683 EALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLR 762
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 939619907 763 NPK-VAVLWLEAIrVELRAGLKEIASTMMARALQECPN 799
Cdd:COG4235   81 DPDnPEALYLLGL-AAFQQGDYAEAIAAWQKLLALLPA 117
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 279-475 1.73e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  279 NDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAAR----LQPPDTAKAVIAQ 354
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQyylgKGQLKKALAILNE 592

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  355 AARHIPTSVRIWIKAADLESETKAKR---RVFRKALEHIPNS----VRLWKAAVELENPDDARILLSRAVECCNTSVELW 427
Cdd:TIGR02917 593 AADAAPDSPEAWLMLGRAQLAAGDLNkavSSFKKLLALQPDSalalLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQ 672

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 939619907  428 LALARLetyENARKVLNKARENIPTDRQIWTTAAKLEEANGNIHMVEK 475
Cdd:TIGR02917 673 IGLAQL---LLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQK 717
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
677-765 1.76e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.09  E-value: 1.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 677 ALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAAtYTLGLKKCPTSIPLWILSANLEERKGVLTKARSIL 756
Cdd:COG3063    4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82


                 ....*....
gi 939619907 757 ERGRLRNPK 765
Cdd:COG3063   83 ERALELDPS 91
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 672-732 2.87e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 45.79  E-value: 2.87e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 939619907  672 ARLEWALEKFDEALRLLEEAVEVFPDFPK---LWMMKGQIEEQQRRTDDAAATYTLGLKKCPTS 732
Cdd:pfam13432   4 ARAALRAGDYDDAAAALEAALARFPESPDaaaALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 608-870 3.01e-06

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 50.29  E-value: 3.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 608 KWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALE--KFDEAL 685
Cdd:COG3071   26 ALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRAELLLDqgQAEQAL 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 686 RLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKK---CPTSIPLWILSANLE------ERKGVLTKARSIL 756
Cdd:COG3071  106 ATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHkalSAEEAQALERRAYLGllrqaaRDAEALKALWKAL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 757 ERGRLRNPKVAvlwLEAIRVELRAGLKEIASTMMARALQECPNAG--ELWAEAIFMETKPQRKtKSVDALKKCEHDPHVL 834
Cdd:COG3071  186 PRAERRDPELA---AAYARALIALGDHDEAERLLREALKRQWDPRlvRLYGRLQGGDPAKQLK-RAEKWLKKHPNDPDLL 261

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 939619907 835 LAVSKLFWSEHKFSKCRDWFNRTVKIDPDlGDAWAY 870
Cdd:COG3071  262 LALGRLCLRNQLWGKAREYLEAALALRPS-AEAYAE 296
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 537-898 3.20e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 3.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  537 AEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPA 616
Cdd:TIGR02917 166 AQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  617 ARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT--PRVMMKSArLEWALEKFDEALRLLEEAVEV 694
Cdd:TIGR02917 246 AEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEylPALLLAGA-SEYQLGNLEQAYQYLNQILKY 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  695 FPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLEERKGVLTKARSILERGRLRNPKVAVLWLEAI 774
Cdd:TIGR02917 325 APNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLG 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  775 RVELRAGLKEIASTMMARALQ---ECPNAGELWAEAIFMETKPQRKTKSVDALKKCEHD---PHVLLAVSKLfwSEHKFS 848
Cdd:TIGR02917 405 ISKLSQGDPSEAIADLETAAQldpELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDnasLHNLLGAIYL--GKGDLA 482

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 939619907  849 KCRDWFNRTVKIDPDLGDAWAYFYKFELLHGTEAQQQEVLDRCISAEPTH 898
Cdd:TIGR02917 483 KAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKN 532
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 567-763 6.24e-06

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 49.42  E-value: 6.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 567 WLRAAyfeknhGTRESLEAL----LQRAVAH--CpksEIlwlmgAKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVK 640
Cdd:PRK11788 157 WQKAI------DVAERLEKLggdsLRVEIAHfyC---EL-----AQQALARGDLDAARALLKKALAADPQCVRASILLGD 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 641 LESENSEYERARRLLAKARGSAP--TPRV---MMKSARlewALEKFDEALRLLEEAVEVFPdFPKLWMMKGQIEEQQRRT 715
Cdd:PRK11788 223 LALAQGDYAAAIEALERVEEQDPeyLSEVlpkLMECYQ---ALGDEAEGLEFLRRALEEYP-GADLLLALAQLLEEQEGP 298

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 939619907 716 DDAAATYTLGLKKCPTS------IPLWILSANLEERKGVLTKARSILERgRLRN 763
Cdd:PRK11788 299 EAAQALLREQLRRHPSLrgfhrlLDYHLAEAEEGRAKESLLLLRDLVGE-QLKR 351
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 644-732 1.14e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.37  E-value: 1.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 644 ENSEYERARRLLAKARGSAP----TPRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKL---WMMKGQIEEQQRRTD 716
Cdd:COG1729    5 KAGDYDEAIAAFKAFLKRYPnsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYD 84

                         90
                 ....*....|....*.
gi 939619907 717 DAAATYTLGLKKCPTS 732
Cdd:COG1729   85 KARATLEELIKKYPDS 100
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 649-758 3.42e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 3.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 649 ERARRLLAKARGSAptpRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKK 728
Cdd:COG4235    4 ARLRQALAANPNDA---EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 939619907 729 CPTSIPLWILSANLEERKGVLTKARSILER 758
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQK 110
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 545-696 4.08e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 4.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 545 AFECARAVYAHALQIFPSKKSIWLRAAYFEKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLA 624
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 939619907 625 FQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFP 696
Cdd:COG5010   81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDnPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 380-481 6.18e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 6.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 380 RRVFRKALEHIPNSVRLW----KAAVELENPDDARILLSRAVECCNTSVELWLALA----RLETYENARKVLNKARENIP 451
Cdd:COG4783   24 EALLEKALELDPDNPEAFallgEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGlallKAGDYDEALALLEKALKLDP 103

                         90       100       110
                 ....*....|....*....|....*....|
gi 939619907 452 TDRQIWTTAAKLEEANGNIHMVEKIIDRSL 481
Cdd:COG4783  104 EHPEAYLRLARAYRALGRPDEAIAALEKAL 133
COG5191 COG5191
Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat [General function ...
 687-778 9.73e-05

Uncharacterized conserved protein, contains HAT (Half-A-TPR) repeat [General function prediction only];


Pssm-ID: 227518 [Multi-domain]  Cd Length: 435  Bit Score: 45.72  E-value: 9.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 687 LLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANLE-ERKGVLTKARSILERGRLRNPK 765
Cdd:COG5191   95 ELYRSTNKFFNDPKIWSQYAAYVIKKKMYGEMKNIFAECLTKHPLNVDLWIYCCAFElFEIANIESSRAMFLKGLRMNSR 174

                         90
                 ....*....|...
gi 939619907 766 VAVLWLEAIRVEL 778
Cdd:COG5191  175 SPRIWIEYFRMEL 187
TPR_19 pfam14559
Tetratricopeptide repeat;
647-708 1.65e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 40.65  E-value: 1.65e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 939619907  647 EYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQI 708
Cdd:pfam14559   3 DYAEALELLEQALAEDPDnAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR_14 pfam13428
Tetratricopeptide repeat;
665-708 2.44e-04

Tetratricopeptide repeat;


Pssm-ID: 463874 [Multi-domain]  Cd Length: 44  Bit Score: 39.33  E-value: 2.44e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 939619907  665 PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQI 708
Cdd:pfam13428   1 PEALLALARALLALGDPDEALALLERALALDPDDPEAWLALAQL 44
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 645-773 4.24e-04

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 43.64  E-value: 4.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 645 NSEYERARRLLAKARGSAPT-PRVMMKSARLEWALEKFDEALRLLEEAVEVFPDFpkLWMMKGQIEEQQRRTDDAAATYT 723
Cdd:PRK11788 193 RGDLDAARALLKKALAADPQcVRASILLGDLALAQGDYAAAIEALERVEEQDPEY--LSEVLPKLMECYQALGDEAEGLE 270

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 939619907 724 LgLKKC----PTSIPLWILSANLEERKGVlTKARSILERGRLRNPKVAVL--WLEA 773
Cdd:PRK11788 271 F-LRRAleeyPGADLLLALAQLLEEQEGP-EAAQALLREQLRRHPSLRGFhrLLDY 324
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 611-697 4.95e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 4.95e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 611 AGDVPAARGILSLAFQANPNSE---DIWLAAVKLESENSEYERA----RRLLAKARGSAPTPRVMMKSARLEWALEKFDE 683
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAaeafEKLLKRYPDSPKAPDALLKLGLSYLELGDYDK 85

                         90
                 ....*....|....
gi 939619907 684 ALRLLEEAVEVFPD 697
Cdd:COG1729   86 ARATLEELIKKYPD 99
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 335-481 5.14e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 5.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 335 LWLEAARLQPPDTAKAVIAQAARHIPTSVRIWIKAADLESETKAKRRVFRKaLEHIPNSVRLWKAAVELeNPDDARILLS 414
Cdd:COG5010   16 LLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNK-LGDFEESLALLEQALQL-DPNNPELYYN 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 939619907 415 RAveccntsvelwLALARLETYENARKVLNKARENIPTDRQIWTTAAKLEEANGNIHMVEKIIDRSL 481
Cdd:COG5010   94 LA-----------LLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 278-393 8.43e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 8.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 278 INDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAA----RLQPPDTAKAVIA 353
Cdd:COG4783   17 AGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGlallKAGDYDEALALLE 96

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 939619907 354 QAARHIPTSVRIWIKAADLESETKAK---RRVFRKALEHIPNS 393
Cdd:COG4783   97 KALKLDPEHPEAYLRLARAYRALGRPdeaIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 335-451 9.88e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 9.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 335 LWLEAARLQPPDTAKAVIAQAARHIPTSVRIWIKAADLESETKAKRRVFRKALEHIPNSVRLW----KAAVELENPDDAR 410
Cdd:COG5010   29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYynlaLLYSRSGDKDEAK 108

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 939619907 411 ILLSRAVECCNTSVELW----LALARLETYENARKVLNKARENIP 451
Cdd:COG5010  109 EYYEKALALSPDNPNAYsnlaALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
611-697 1.07e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 1.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 611 AGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEE 690
Cdd:COG3063    5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                 ....*..
gi 939619907 691 AVEVFPD 697
Cdd:COG3063   85 ALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 333-458 1.20e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 42.67  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 333 EDLWLEAARLQPPDTAKAVIAQAARHIPTSVRIWIKAADLESETKAK---RRVFRKALEHIPNSVRLW----KAAVELEN 405
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLeeaLAALRRALALNPDFAEAYlnlgEALRRLGR 161

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 939619907 406 PDDARILLSRAVECCNTSVELWLALAR----LETYENARKVLNKARENIPTDRQIWT 458
Cdd:COG3914  162 LEEAIAALRRALELDPDNAEALNNLGNalqdLGRLEEAIAAYRRALELDPDNADAHS 218
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 563-693 2.08e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.43  E-value: 2.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 563 KKSIWLRAAYFEK--NHGTRESLEALLQRAVAHCPKSEILWLMGAKskwMAGDVPAARGILSLAFQANPNSEDIWLAAVK 640
Cdd:COG3071  190 RRDPELAAAYARAliALGDHDEAERLLREALKRQWDPRLVRLYGRL---QGGDPAKQLKRAEKWLKKHPNDPDLLLALGR 266

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 939619907 641 LESENSEYERARRLLAKARGSAPTPRVMMKSARLEWALEKFDEALRLLEEAVE 693
Cdd:COG3071  267 LCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALA 319
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 611-727 2.52e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.05  E-value: 2.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 611 AGDVPAARGILSLAFQANPNSEdiwLAAVKLESENSEYERARRLLAKARGSAP-TPRVMMKSARLEWALEKFDEALRLLE 689
Cdd:COG3071  206 LGDHDEAERLLREALKRQWDPR---LVRLYGRLQGGDPAKQLKRAEKWLKKHPnDPDLLLALGRLCLRNQLWGKAREYLE 282

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 939619907 690 EAVEVFPDfPKLWMMKGQIEEQQRRTDDAAATYTLGLK 727
Cdd:COG3071  283 AALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALA 319
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 434-466 2.55e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.37  E-value: 2.55e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 939619907   434 ETYENARKVLNKARENIPTDRQIWTTAAKLEEA 466
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 586-863 2.83e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  586 LLQRAVAHCPK-SEILWLMGaKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPT 664
Cdd:TIGR02917  44 QLKNALQKDPNdAEARFLLG-KIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLDDE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  665 PRVMMKSAR--LEWALEKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:TIGR02917 123 GAAELLALRglAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDL 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907  743 EERKGVLTKARSILERGRLRNPKVAVLWLEAIRVELRAGLKEIAS----TMMARALQEcPNAGELWAEAIFMETKPQR-K 817
Cdd:TIGR02917 203 LLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEkhadALLKKAPNS-PLAHYLKALVDFQKKNYEDaR 281

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 939619907  818 TKSVDALKKC-EHDPHVLLAVSKLFwSEHKFSKCRDWFNRTVKIDPD 863
Cdd:TIGR02917 282 ETLQDALKSApEYLPALLLAGASEY-QLGNLEQAYQYLNQILKYAPN 327
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 546-576 4.35e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 35.60  E-value: 4.35e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 939619907   546 FECARAVYAHALQIFPSKKSIWLRAAYFEKN 576
Cdd:smart00386   3 IERARKIYERALEKFPKSVELWLKYAEFEER 33
TPR_19 pfam14559
Tetratricopeptide repeat;
679-742 4.67e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 36.41  E-value: 4.67e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 939619907  679 EKFDEALRLLEEAVEVFPDFPKLWMMKGQIEEQQRRTDDAAATYTLGLKKCPTSIPLWILSANL 742
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 368-478 4.91e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 4.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 368 KAADL--ESETKAKRRVFRKALEHIPNSVRLWKAA----VELENPDDARILLSRAVECC-NTSVELWLALARLETYENAR 440
Cdd:cd24142    6 KAEELldQGNFELALKFLQRALELEPNNVEALELLgeilLELGDVEEAREVLLRAIELDpDGGYEKYLYLGQLSGGEEAL 85

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 939619907 441 KVLNKARENIptDRQIWTTAAKLEEANGNI-HMVEKIID 478
Cdd:cd24142   86 QYYEKGIEIL--EEELQALQAASAEAEEEAeELKRKLSS 122
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 293-418 5.45e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 5.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 293 ETNPNHPPAWIASARLEEVTGKVQMARNLIMRGCEMNIQSEDLWLEAARL----QPPDTAKAVIAQAARHIPTSVRIWIK 368
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAllaaGDTEEAEELLERALALDPDNPEALYL 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 939619907 369 AADLESETKAkrrvFRKALEHipnsvrlWKAAVELENPDDARILLSRAVE 418
Cdd:COG4235   91 LGLAAFQQGD----YAEAIAA-------WQKLLALLPADAPARLLEASIA 129
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 494-631 6.62e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 6.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 494 DQWFQEAIEAEKSGAVNCCQSIVKAVIgigVEEEDRKQTWIDDAEFCAKENAFECARAVYAHALQIFPSKKSIWLRAAYF 573
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKAL---ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 939619907 574 EKNHGTRESLEALLQRAVAHCPKSEILWLMGAKSKWMAGDVPAARGILSLAFQANPNS 631
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 589-699 7.02e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 39.87  E-value: 7.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 589 RAVAHCPKSEILWLMG-AKSKWMAGDVPAARGILSLAFQANPNSEDIWLAAVKLESENSEYERARRLLAKARGSAPTPRV 667
Cdd:COG3898  142 EAMLEDPETRFLGLRGlMVEALRRGDTEAALALAEEALALAPKLPWAQDALLELQAAAGDWDGALATLDAALKAGLLDKD 221

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 939619907 668 MMKSAR--LEW--ALEKFD----EALRLLEEAVEVFPDFP 699
Cdd:COG3898  222 VARRRRavLLTarARELEEgdpdEARELAIEALKLAPDLV 261
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 636-728 8.82e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 38.68  E-value: 8.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 636 LAAVKLESENSEYERARRLLAKARGSAPTP----RVMMKSARLEWALEKFDEALRLLEEAVEvfPDF-PKLWMMKGQIEE 710
Cdd:COG2976   94 LLLAKAAVDAGDLDKAAAQLQWVLDNAKDPalkaLARLRLARVLLAQKKYDEALATLDAVKP--EAFaALYAELRGDILL 171

                         90
                 ....*....|....*...
gi 939619907 711 QQRRTDDAAATYTLGLKK 728
Cdd:COG2976  172 AQGDKAEARAAYQKALAA 189
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 279-418 9.01e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.94  E-value: 9.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939619907 279 NDIKKARLLLKSVRETNPNHPPAWIASARLEEVTGKVQMArnlimrgcemniqsEDLWLEAARLQPPDtakaviAQAARH 358
Cdd:COG2956  158 GDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEA--------------IAALERALEQDPDY------LPALPR 217

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 939619907 359 IptsvriwIKAADLESETKAKRRVFRKALEHIPNS---VRLWKAAVELENPDDARILLSRAVE 418
Cdd:COG2956  218 L-------AELYEKLGDPEEALELLRKALELDPSDdllLALADLLERKEGLEAALALLERQLR 273
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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