|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
72-400 |
1.32e-114 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 340.35 E-value: 1.32e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 72 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWSVET 151
Cdd:COG2319 73 TLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFS-PDGKTLASGSADGTVRLWDLAT 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 152 GKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 231
Cdd:COG2319 152 GKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLW 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 232 DADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGT 311
Cdd:COG2319 232 DLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGT 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 312 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGS 391
Cdd:COG2319 312 VRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGS 391
|
....*....
gi 1051784925 392 KDNTCRIWR 400
Cdd:COG2319 392 ADGTVRLWD 400
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
72-400 |
1.44e-104 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 314.54 E-value: 1.44e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 72 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFnNPYGDKIATGSFDKTCKLWSVET 151
Cdd:COG2319 31 LLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAF-SPDGRLLASASADGTVRLWDLAT 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 152 GKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 231
Cdd:COG2319 110 GLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 232 DADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGT 311
Cdd:COG2319 190 DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGT 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 312 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGS 391
Cdd:COG2319 270 VRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGS 349
|
....*....
gi 1051784925 392 KDNTCRIWR 400
Cdd:COG2319 350 DDGTVRLWD 358
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
72-361 |
5.63e-104 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 313.00 E-value: 5.63e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 72 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWSVET 151
Cdd:COG2319 115 TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFS-PDGKLLASGSDDGTVRLWDLAT 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 152 GKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 231
Cdd:COG2319 194 GKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLW 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 232 DADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGT 311
Cdd:COG2319 274 DLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGT 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1051784925 312 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQT 361
Cdd:COG2319 354 VRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
111-400 |
2.79e-93 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 281.53 E-value: 2.79e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 111 ELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWD 190
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFS-PDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 191 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTC 270
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 271 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSS 350
Cdd:cd00200 160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSE 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1051784925 351 DKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIWR 400
Cdd:cd00200 240 DGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
69-358 |
3.19e-90 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 273.83 E-value: 3.19e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 69 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFnNPYGDKIATGSFDKTCKLWS 148
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAA-SADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 149 VETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTV 228
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 229 VVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASA 308
Cdd:cd00200 160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSE 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1051784925 309 DGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 358
Cdd:cd00200 240 DGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
94-399 |
1.11e-89 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 276.41 E-value: 1.11e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 94 TGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 173
Cdd:COG2319 11 AASADLALALLAAALGALLLLLLGLAAAVASLAAS-PDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 174 STLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSAS 253
Cdd:COG2319 90 GRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 254 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEI 333
Cdd:COG2319 170 FSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSV 249
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1051784925 334 SKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 399
Cdd:COG2319 250 RSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLW 315
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
71-319 |
1.36e-82 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 258.30 E-value: 1.36e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 71 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFnNPYGDKIATGSFDKTCKLWSVE 150
Cdd:COG2319 156 RTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAF-SPDGKLLASGSADGTVRLWDLA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 151 TGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVV 230
Cdd:COG2319 235 TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 231 WDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 310
Cdd:COG2319 315 WDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADG 394
|
....*....
gi 1051784925 311 TARIFSAAT 319
Cdd:COG2319 395 TVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
132-400 |
2.68e-74 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 236.73 E-value: 2.68e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 132 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLS 211
Cdd:COG2319 6 GAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 212 FNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEI 291
Cdd:COG2319 86 FSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 292 LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGH 371
Cdd:COG2319 166 TSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGH 245
|
250 260
....*....|....*....|....*....
gi 1051784925 372 TDEIFSCAFNYKGNIVITGSKDNTCRIWR 400
Cdd:COG2319 246 SGSVRSVAFSPDGRLLASGSADGTVRLWD 274
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
39-277 |
1.01e-66 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 217.09 E-value: 1.01e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 39 LLTASRTEQVKLLiqrlqeklgqnSNHTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGH 118
Cdd:COG2319 177 LASGSDDGTVRLW-----------DLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGH 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 119 RNVVYAIAFnNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 198
Cdd:COG2319 246 SGSVRSVAF-SPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLR 324
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1051784925 199 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATN 277
Cdd:COG2319 325 TLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
169-399 |
3.47e-58 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 195.13 E-value: 3.47e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 169 SFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE 248
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 249 ISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEG 328
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTG 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1051784925 329 HEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 399
Cdd:COG2319 161 HSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLW 231
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
66-232 |
2.00e-43 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 152.87 E-value: 2.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 66 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFnNPYGDKIATGSFDKTCK 145
Cdd:cd00200 124 TGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVAF-SPDGEKLLSSSSDGTIK 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 146 LWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFD 225
Cdd:cd00200 203 LWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSAD 282
|
....*..
gi 1051784925 226 HTVVVWD 232
Cdd:cd00200 283 GTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
211-400 |
9.37e-41 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 148.91 E-value: 9.37e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 211 SFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDE 290
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 291 ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEG 370
Cdd:COG2319 81 VLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTG 160
|
170 180 190
....*....|....*....|....*....|
gi 1051784925 371 HTDEIFSCAFNYKGNIVITGSKDNTCRIWR 400
Cdd:COG2319 161 HSGAVTSVAFSPDGKLLASGSDDGTVRLWD 190
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
83-287 |
4.12e-14 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 73.97 E-value: 4.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 83 VALNKSGSCFITGSYDRTCKLWDTAS----GEELN----TLEGhRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETGKC 154
Cdd:PLN00181 489 IGFDRDGEFFATAGVNKKIKIFECESiikdGRDIHypvvELAS-RSKLSGICWNSYIKSQVASSNFEGVVQVWDVARSQL 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 155 YHTFRGHTAEIVCLSFNPQS-TLVATGSMDTTAKLWDIQNGEEVYTLRGhSAEIISLSF-NTSGDRIITGSFDHTVVVWD 232
Cdd:PLN00181 568 VTEMKEHEKRVWSIDYSSADpTLLASGSDDGSVKLWSINQGVSIGTIKT-KANICCVQFpSESGRSLAFGSADHKVYYYD 646
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1051784925 233 ADTGR-KVNILIGHCAEISSASFnWDCSLILTGSMDKTCKLWDAT------NGKCVATLTGH 287
Cdd:PLN00181 647 LRNPKlPLCTMIGHSKTVSYVRF-VDSSTLVSSSTDNTLKLWDLSmsisgiNETPLHSFMGH 707
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
160-287 |
3.26e-11 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 64.53 E-value: 3.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 160 GHTAEIVCLSFNP-QSTLVATGSMDTTAKLWDI------QN-GEEVYTLRGHSAEIISLSFNTSGDRII-TGSFDHTVVV 230
Cdd:PTZ00421 73 GQEGPIIDVAFNPfDPQKLFTASEDGTIMGWGIpeegltQNiSDPIVHLQGHTKKVGIVSFHPSAMNVLaSAGADMVVNV 152
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1051784925 231 WDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGH 287
Cdd:PTZ00421 153 WDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAH 209
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
284-398 |
8.60e-11 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 63.37 E-value: 8.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 284 LTGHDDEILDSCFD-YTGKLIATASADGTarIF------SAATRKC---IAKLEGHEGEISKISFNPQGNHLL-TGSSDK 352
Cdd:PTZ00421 71 LLGQEGPIIDVAFNpFDPQKLFTASEDGT--IMgwgipeEGLTQNIsdpIVHLQGHTKKVGIVSFHPSAMNVLaSAGADM 148
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1051784925 353 TARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRI 398
Cdd:PTZ00421 149 VVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNI 194
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
319-358 |
8.85e-10 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 53.47 E-value: 8.85e-10
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 319 TRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 358
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
151-190 |
1.33e-09 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 53.09 E-value: 1.33e-09
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 151 TGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWD 190
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
161-394 |
2.91e-09 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 58.94 E-value: 2.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 161 HTAEIVC-LSFNPQSTLVATGSMDTTAKLWD----IQNGEEVY----TLRGHSaEIISLSFNTS-GDRIITGSFDHTVVV 230
Cdd:PLN00181 481 NSSNLVCaIGFDRDGEFFATAGVNKKIKIFEcesiIKDGRDIHypvvELASRS-KLSGICWNSYiKSQVASSNFEGVVQV 559
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 231 WDADTGRKVNILIGH-----CAEISSAsfnwDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEildSCFDY---TGKL 302
Cdd:PLN00181 560 WDVARSQLVTEMKEHekrvwSIDYSSA----DPTLLASGSDDGSVKLWSINQGVSIGTIKTKANI---CCVQFpseSGRS 632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 303 IATASADGTARIFSAATRKC-IAKLEGHEGEISKISFnPQGNHLLTGSSDKTARIWDAQTGQC------LQVLEGHTDEI 375
Cdd:PLN00181 633 LAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRF-VDSSTLVSSSTDNTLKLWDLSMSISginetpLHSFMGHTNVK 711
|
250
....*....|....*....
gi 1051784925 376 FSCAFNYKGNIVITGSKDN 394
Cdd:PLN00181 712 NFVGLSVSDGYIATGSETN 730
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
152-190 |
3.37e-09 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 51.96 E-value: 3.37e-09
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 152 GKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWD 190
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
361-399 |
3.55e-09 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 51.93 E-value: 3.55e-09
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 361 TGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 399
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
320-358 |
1.02e-08 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 50.81 E-value: 1.02e-08
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 320 RKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWD 358
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
362-399 |
1.38e-08 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 50.42 E-value: 1.38e-08
10 20 30
....*....|....*....|....*....|....*...
gi 1051784925 362 GQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 399
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
193-232 |
3.76e-08 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 48.85 E-value: 3.76e-08
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 193 NGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 232
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
79-233 |
1.36e-07 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 53.36 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 79 PLTNVALNK-SGSCFITGSYDRTCKLWDT-ASGEELNT------LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVE 150
Cdd:PTZ00421 77 PIIDVAFNPfDPQKLFTASEDGTIMGWGIpEEGLTQNIsdpivhLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 151 TGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAE-------------IISLSFNTSGD 217
Cdd:PTZ00421 157 RGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAksqrclwakrkdlIITLGCSKSQQ 236
|
170
....*....|....*.
gi 1051784925 218 RiitgsfdhTVVVWDA 233
Cdd:PTZ00421 237 R--------QIMLWDT 244
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
194-232 |
1.57e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 47.34 E-value: 1.57e-07
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 194 GEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 232
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| PTZ00421 |
PTZ00421 |
coronin; Provisional |
200-335 |
2.70e-07 |
|
coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 52.59 E-value: 2.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 200 LRGHSAEIISLSFNTSGD-RIITGSFDHTVVVWDADT-GRKVNI------LIGHCAEISSASFNWDCSLIL-TGSMDKTC 270
Cdd:PTZ00421 71 LLGQEGPIIDVAFNPFDPqKLFTASEDGTIMGWGIPEeGLTQNIsdpivhLQGHTKKVGIVSFHPSAMNVLaSAGADMVV 150
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1051784925 271 KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISK 335
Cdd:PTZ00421 151 NVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQ 215
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
277-316 |
4.40e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.15 E-value: 4.40e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 277 NGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 316
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
108-148 |
6.02e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.77 E-value: 6.02e-07
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1051784925 108 SGEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWS 148
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFS-PDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
235-274 |
9.93e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 45.00 E-value: 9.93e-07
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 235 TGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 274
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
278-316 |
2.32e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 43.87 E-value: 2.32e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 278 GKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFS 316
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
109-148 |
2.56e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 43.87 E-value: 2.56e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 109 GEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCKLWS 148
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFS-PDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
236-274 |
3.27e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 43.49 E-value: 3.27e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1051784925 236 GRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 274
Cdd:pfam00400 1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| NBCH_WD40 |
pfam20426 |
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ... |
135-270 |
4.57e-05 |
|
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.
Pssm-ID: 466575 [Multi-domain] Cd Length: 350 Bit Score: 45.06 E-value: 4.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 135 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIqngeevytLRGHSAEIISLSFNT 214
Cdd:pfam20426 97 ISCGNWENSFQVISLNDGRMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMVWEV--------LRGRSSEKRSRNTQT 168
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1051784925 215 SGDRIitgsfDHTVVvwdadtGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTC 270
Cdd:pfam20426 169 EFPRK-----DHVIA------ETPFHILCGHDDIITCLYVSVELDIVISGSKDGTC 213
|
|
| NBCH_WD40 |
pfam20426 |
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ... |
277-396 |
4.74e-05 |
|
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.
Pssm-ID: 466575 [Multi-domain] Cd Length: 350 Bit Score: 45.06 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 277 NGKCVATLTGHDDEILDSCFDYTGKLIATASADGtarifsaatrKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARI 356
Cdd:pfam20426 81 GAQCFATLQTPSENFLISCGNWENSFQVISLNDG----------RMVQSIRQHKDVVSCVAVTSDGSILATGSYDTTVMV 150
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1051784925 357 WDAQTGQCLQ-----------------------VLEGHTDEIFSCAFNYKGNIVITGSKDNTC 396
Cdd:pfam20426 151 WEVLRGRSSEkrsrntqtefprkdhviaetpfhILCGHDDIITCLYVSVELDIVISGSKDGTC 213
|
|
| PTZ00420 |
PTZ00420 |
coronin; Provisional |
115-217 |
4.87e-05 |
|
coronin; Provisional
Pssm-ID: 240412 [Multi-domain] Cd Length: 568 Bit Score: 45.33 E-value: 4.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 115 LEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSV--------ETGKCYHTFRGHTAEIVCLSFNPQST-LVATGSMDTT 185
Cdd:PTZ00420 70 LKGHTSSILDLQFNPCFSEILASGSEDLTIRVWEIphndesvkEIKDPQCILKGHKKKISIIDWNPMNYyIMCSSGFDSF 149
|
90 100 110
....*....|....*....|....*....|..
gi 1051784925 186 AKLWDIQNGEEVYTLRgHSAEIISLSFNTSGD 217
Cdd:PTZ00420 150 VNIWDIENEKRAFQIN-MPKKLSSLKWNIKGN 180
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
66-105 |
5.61e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 39.99 E-value: 5.61e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1051784925 66 TFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWD 105
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
71-105 |
2.06e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 38.48 E-value: 2.06e-04
10 20 30
....*....|....*....|....*....|....*
gi 1051784925 71 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWD 105
Cdd:pfam00400 5 KTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
302-375 |
5.37e-04 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 38.80 E-value: 5.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 302 LIATASADGT--------ARIFSAAtrkciakLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTD 373
Cdd:pfam12894 9 LIALATEDGElllhrlnwQRVWTLS-------PDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSD 81
|
..
gi 1051784925 374 EI 375
Cdd:pfam12894 82 LI 83
|
|
| PTZ00420 |
PTZ00420 |
coronin; Provisional |
197-279 |
1.55e-03 |
|
coronin; Provisional
Pssm-ID: 240412 [Multi-domain] Cd Length: 568 Bit Score: 40.70 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 197 VYTLRGHSAEIISLSFNTSGDRII-TGSFDHTVVVWD-ADTGRKVN-------ILIGHCAEISSASFNWDCSLILTGS-M 266
Cdd:PTZ00420 67 VIKLKGHTSSILDLQFNPCFSEILaSGSEDLTIRVWEiPHNDESVKeikdpqcILKGHKKKISIIDWNPMNYYIMCSSgF 146
|
90
....*....|...
gi 1051784925 267 DKTCKLWDATNGK 279
Cdd:PTZ00420 147 DSFVNIWDIENEK 159
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
145-213 |
3.06e-03 |
|
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 36.49 E-value: 3.06e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1051784925 145 KLWSVETGKcyhtfrgHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFN 213
Cdd:pfam12894 28 RVWTLSPDK-------EDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
|
|
| ANAPC4_WD40 |
pfam12894 |
Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped ... |
276-339 |
3.09e-03 |
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Anaphase-promoting complex subunit 4 WD40 domain; Apc4 contains an N-terminal propeller-shaped WD40 domain.The N-terminus of Afi1 serves to stabilize the union between Apc4 and Apc5, both of which lie towards the bottom-front of the APC,
Pssm-ID: 403945 [Multi-domain] Cd Length: 91 Bit Score: 36.49 E-value: 3.09e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1051784925 276 TNGKCV--ATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFN 339
Cdd:pfam12894 24 LNWQRVwtLSPDKEDLEVTSLAWRPDGKLLAVGYSDGTVRLLDAENGKIVHHFSAGSDLITCLGWG 89
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| PTZ00421 |
PTZ00421 |
coronin; Provisional |
221-371 |
5.82e-03 |
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coronin; Provisional
Pssm-ID: 173611 [Multi-domain] Cd Length: 493 Bit Score: 38.72 E-value: 5.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 221 TGSFDHTvvvwdaDTGRKVN---ILIGHCAEISSASFN-WDCSLILTGSMDKTCKLWD-ATNG------KCVATLTGHDD 289
Cdd:PTZ00421 53 TAVLKHT------DYGKLASnppILLGQEGPIIDVAFNpFDPQKLFTASEDGTIMGWGiPEEGltqnisDPIVHLQGHTK 126
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 290 EILDSCFDYTGK-LIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL 368
Cdd:PTZ00421 127 KVGIVSFHPSAMnVLASAGADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSV 206
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...
gi 1051784925 369 EGH 371
Cdd:PTZ00421 207 EAH 209
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| NBCH_WD40 |
pfam20426 |
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ... |
79-201 |
7.83e-03 |
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Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.
Pssm-ID: 466575 [Multi-domain] Cd Length: 350 Bit Score: 38.13 E-value: 7.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1051784925 79 PLT-NVALnkSGSCFIT-----GSYDRTCKLWDTA-------SGEELNTLEGHRNVVYAIAFNnPYGDKIATGSFDKTCK 145
Cdd:pfam20426 73 PLAeNVEL--GAQCFATlqtpsENFLISCGNWENSfqvislnDGRMVQSIRQHKDVVSCVAVT-SDGSILATGSYDTTVM 149
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90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1051784925 146 LWSVETGKC-----------------------YHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLR 201
Cdd:pfam20426 150 VWEVLRGRSsekrsrntqtefprkdhviaetpFHILCGHDDIITCLYVSVELDIVISGSKDGTCIFHTLREGRYVRSIR 228
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