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Conserved domains on  [gi|1063716562|ref|NP_001319737|]
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Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-315 7.04e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 7.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 113 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 189
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 190 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 269
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716562 270 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 315
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-315 7.04e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 7.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 113 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 189
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 190 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 269
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716562 270 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 315
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 112-310 8.64e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 8.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPlRVEAYHGLLmaySDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKllvAQIRVIEGKHSEALKLYQELVKEEPR 271
Cdd:TIGR02917 221 ALRP-NNIAVLLAL---ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK---ALVDFQKKNYEDARETLQDALKSAPE 293

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1063716562 272 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYR 310
Cdd:TIGR02917 294 YLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQAR 332
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-315 7.04e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 7.04e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 113 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 189
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 190 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 269
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716562 270 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 315
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 141-310 1.31e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 1.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 141 IKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVES 220
Cdd:COG2956    19 LLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG-LLDRAEE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 221 RIEEAMlkckkENNQNDfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFR 300
Cdd:COG2956    98 LLEKLL-----ELDPDD-AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                         170
                  ....*....|
gi 1063716562 301 KLVPKNHPYR 310
Cdd:COG2956   172 KLDPDCARAL 181
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
127-336 2.27e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.88  E-value: 2.27e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 127 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLM 206
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 207 AYSDAGldlkevesRIEEAMLKCKK--ENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYT 284
Cdd:COG0457    85 ALQALG--------RYEEALEDYDKalELDPDDAEALYNL-GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063716562 285 LLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATKLFSEKAQREMAEEMA 336
Cdd:COG0457   156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 112-295 7.72e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 7.72e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPR 271
Cdd:COG2956   172 KLDPDCARALLLLAELYLEQG-DYEEAIAALERAL-----EQDPDYLPALPRL-AELYEKLGDPEEALELLRKALELDPS 244

                         170       180
                  ....*....|....*....|....
gi 1063716562 272 DfRPYLCQGIIYTLLKKKDKAEEQ 295
Cdd:COG2956   245 D-DLLLALADLLERKEGLEAALAL 267
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 128-306 2.34e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 2.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 128 SDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMA 207
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 208 YSDAGldlkevesrieeamlkckkennqndfrdfkllvaqirviegKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLK 287
Cdd:COG4783    82 LLKAG-----------------------------------------DYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         170
                  ....*....|....*....
gi 1063716562 288 KKDKAEEQFDNFRKLVPKN 306
Cdd:COG4783   121 RPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 114-336 5.16e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 5.16e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 114 EEERALDEH---LITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEI 190
Cdd:COG2956    57 EYDRAIRIHqklLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 191 LAKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEP 270
Cdd:COG2956   137 LKLGPENAHAYCELAELYLEQG-DYDEAIEALEKAL-----KLDPDCARALLLL-AELYLEQGDYEEAIAALERALEQDP 209

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063716562 271 RDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFmdNMIATKLFSEKAQREMAEEMA 336
Cdd:COG2956   210 DYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALA--DLLERKEGLEAALALLERQLR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 112-226 1.16e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.75  E-value: 1.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG4783    20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAM 226
Cdd:COG4783   100 KLDPEHPEAYLRLARAYRALG-RPDEAIAALEKAL 133
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 114-212 9.19e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.17  E-value: 9.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 114 EEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAK 193
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90
                  ....*....|....*....
gi 1063716562 194 DPLRVEAYHGLLMAYSDAG 212
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQG 99
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 169-312 4.41e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 4.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 169 LKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkEVEsRIEEAMLKCKKENNQNDFRDFKLlvAQI 248
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG----EYD-RAIRIHQKLLERDPDRAEALLEL--AQD 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063716562 249 RVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN-HPYREY 312
Cdd:COG2956    86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENaHAYCEL 150
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 112-310 8.64e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 8.64e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPlRVEAYHGLLmaySDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKllvAQIRVIEGKHSEALKLYQELVKEEPR 271
Cdd:TIGR02917 221 ALRP-NNIAVLLAL---ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK---ALVDFQKKNYEDARETLQDALKSAPE 293

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1063716562 272 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYR 310
Cdd:TIGR02917 294 YLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQAR 332
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 148-310 2.53e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 2.53e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 148 EAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLlmaysdagldlkevesrieeaml 227
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL----------------------- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 228 kckkennqndfrdfkllvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNH 307
Cdd:COG4235    58 ------------------AEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119


                  ...
gi 1063716562 308 PYR 310
Cdd:COG4235   120 PAR 122
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 127-312 2.74e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 2.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 127 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKL-EPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGL- 204
Cdd:TIGR02917  87 YPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLdDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLa 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 205 --LMAYSdaglDLKEVESRIEEAMLKckkennQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGII 282
Cdd:TIGR02917 167 qlALAEN----RFDEARALIDEVLTA------DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATI 236

                         170       180       190
                  ....*....|....*....|....*....|
gi 1063716562 283 YTLLKKKDKAEEQFDNFRKLVPkNHPYREY 312
Cdd:TIGR02917 237 LIEAGEFEEAEKHADALLKKAP-NSPLAHY 265
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
191-312 5.70e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.01  E-value: 5.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 191 LAKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAMLKCKK--ENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKE 268
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLG--------RYEEAIEDYEKalELDPDDAEALYNL-GLAYLRLGRYEEALADYEQALEL 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1063716562 269 EPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREY 312
Cdd:COG0457    72 DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYN 115
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 112-212 7.69e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.76  E-value: 7.69e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG3914   128 LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRAL 207

                          90       100
                  ....*....|....*....|.
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAG 212
Cdd:COG3914   208 ELDPDNADAHSNLLFALRQAC 228
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 246-336 1.03e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 1.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 246 AQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATKLFsE 325
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY-D 89

                          90
                  ....*....|.
gi 1063716562 326 KAQREMAEEMA 336
Cdd:COG4783    90 EALALLEKALK 100
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 112-197 1.18e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 1.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG5010    70 FEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                  ....*.
gi 1063716562 192 AKDPLR 197
Cdd:COG5010   150 GTSPLK 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
112-295 1.43e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.85  E-value: 1.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG0457    58 YEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAMLKCKKENNQNdfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPR 271
Cdd:COG0457   138 ELDPDDADALYNLGIALEKLG--------RYEEALELLEKLEAAA--LAALLAAALGEAALALAAAEVLLALLLALEQAL 207

                         170       180
                  ....*....|....*....|....
gi 1063716562 272 DFRPYLCQGIIYTLLKKKDKAEEQ 295
Cdd:COG0457   208 RKKLAILTLAALAELLLLALALLL 231
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 112-226 4.19e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 4.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG3914    94 YEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL 173

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAM 226
Cdd:COG3914   174 ELDPDNAEALNNLGNALQDLG--------RLEEAI 200
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 112-195 4.71e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 4.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG4783    54 LDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133


                  ....
gi 1063716562 192 AKDP 195
Cdd:COG4783   134 ELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 171-308 8.47e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 8.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 171 ANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLlmaysdagldlkevesrieeamlkckkennqndfrdfkllvAQIRV 250
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALL-----------------------------------------GEILL 49

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063716562 251 IEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPkNHP 308
Cdd:COG4783    50 QLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP-EHP 106
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 113-308 2.56e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 2.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 113 EEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILA 192
Cdd:TIGR02917 652 AKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALK 731

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 193 KDPLRVEAYhGLLMAYSDAGlDLKEVESRIeEAMLKckkeNNQNDFRdFKLLVAQIRVIEGKHSEALKLYQELVKEEPrD 272
Cdd:TIGR02917 732 RAPSSQNAI-KLHRALLASG-NTAEAVKTL-EAWLK----THPNDAV-LRTALAELYLAQKDYDKAIKHYQTVVKKAP-D 802

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063716562 273 FRPYLcQGIIYTLLKKKD-KAEEQFDNFRKLVPKNHP 308
Cdd:TIGR02917 803 NAVVL-NNLAWLYLELKDpRALEYAERALKLAPNIPA 838
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
171-334 2.58e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.91  E-value: 2.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 171 ANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkevesrieeamlkckkennqndfrDFKllvaqirv 250
Cdd:COG4785    80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLG---------------------------DYD-------- 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 251 iegkhsEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPkNHPYReYFMDNMIATKLFSEKAQRE 330
Cdd:COG4785   125 ------AALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDP-NDPER-ALWLYLAERKLDPEKALAL 196


                  ....
gi 1063716562 331 MAEE 334
Cdd:COG4785   197 LLED 200
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 112-225 2.66e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 2.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG4235    33 YDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1063716562 192 AKDPlrveayhgllmaysdAGLDLKEVESRIEEA 225
Cdd:COG4235   113 ALLP---------------ADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 112-308 3.79e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 3.79e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:TIGR02917 311 LEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKAT 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckKENNQNDFRDFKLLVAQIRviEGKHSEALKLYQELVKEEPR 271
Cdd:TIGR02917 391 ELDPENAAARTQLGISKLSQG-DPSEAIADLETAA----QLDPELGRADLLLILSYLR--SGQFDKALAAAKKLEKKQPD 463

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063716562 272 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHP 308
Cdd:TIGR02917 464 NASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFP 500
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
178-274 6.57e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 6.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 178 GDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAmLKCKK--ENNQNDFRDFKLLvAQIRVIEGKH 255
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG--------RYDEA-IALEKalKLDPNNAEALLNL-AELLLELGDY 75

                          90
                  ....*....|....*....
gi 1063716562 256 SEALKLYQELVKEEPRDFR 274
Cdd:COG3063    76 DEALAYLERALELDPSALR 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 127-321 7.92e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 7.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 127 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLM 206
Cdd:TIGR02917 428 PELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLAR 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 207 aysdagLDLKevESRIE------EAMLKCKKENNqndfrDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQG 280
Cdd:TIGR02917 508 ------IDIQ--EGNPDdaiqrfEKVLTIDPKNL-----RAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALA 574

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063716562 281 IIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATK 321
Cdd:TIGR02917 575 QYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAG 615
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 142-226 1.43e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.87  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 142 KSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVESR 221
Cdd:COG5010    66 KLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-QDDEAKAA 144


                  ....*
gi 1063716562 222 IEEAM 226
Cdd:COG5010   145 LQRAL 149
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
126-297 3.07e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.44  E-value: 3.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 126 HPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLL 205
Cdd:COG4785    69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 206 MAYSDAGldlkevesRIEEA---MLKCKKENNQNDFRDFKLLVAQIRViegKHSEALKLYQELVkeeprdFRPYLCQGii 282
Cdd:COG4785   149 IALYYLG--------RYELAiadLEKALELDPNDPERALWLYLAERKL---DPEKALALLLEDW------ATAYLLQG-- 209

                         170
                  ....*....|....*
gi 1063716562 283 ytllkKKDKAEEQFD 297
Cdd:COG4785   210 -----DTEEARELFK 219
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
139-226 4.86e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 139 VKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTgFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEV 218
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-DYDEA 78


                  ....*...
gi 1063716562 219 ESRIEEAM 226
Cdd:COG3063    79 LAYLERAL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 187-306 5.83e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 5.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 187 FEEILAKDPLRVEAYHGLLMAYSDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELV 266
Cdd:COG5010     2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1063716562 267 KEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN 306
Cdd:COG5010    82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN 121
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 112-270 6.23e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 6.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG5010     2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEP 270
Cdd:COG5010    82 QLDPNNPELYYNLALLYSRSG-DKDEAKEYYEKAL-----ALSPDNPNAYSNL-AALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
112-195 7.12e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 7.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEvIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:COG3063     8 LEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERAL 86


                  ....
gi 1063716562 192 AKDP 195
Cdd:COG3063    87 ELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 118-306 9.40e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 9.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 118 ALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLR 197
Cdd:TIGR02917 589 ILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 198 VEAYHGLLMAY------SDAGLDLKEVESRIEEAMLKCKKENN----QNDFRD----FK------------LLVAQIRVI 251
Cdd:TIGR02917 669 TEAQIGLAQLLlaakrtESAKKIAKSLQKQHPKAALGFELEGDlylrQKDYPAaiqaYRkalkrapssqnaIKLHRALLA 748

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063716562 252 EGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN 306
Cdd:TIGR02917 749 SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDN 803
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 155-304 1.11e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 155 RLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENN 234
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-DFEESLALLEQAL-----QLD 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 235 QNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVP 304
Cdd:COG5010    85 PNNPELYYNL-ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 112-294 1.17e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 191
Cdd:TIGR02917 481 LAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAA 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkeNNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPR 271
Cdd:TIGR02917 561 ELNPQEIEPALALAQYYLGKG-QLKKALAILNEAA------DAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPD 633

                         170       180
                  ....*....|....*....|...
gi 1063716562 272 DFRPYLCQGIIYTLLKKKDKAEE 294
Cdd:TIGR02917 634 SALALLLLADAYAVMKNYAKAIT 656
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
112-269 1.64e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 112 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAktgfEEIL 191
Cdd:COG0457    92 YEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA----LELL 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063716562 192 AKDPLRVEAYHGLLMAYSDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEE 269
Cdd:COG0457   168 EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 141-308 4.97e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 4.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 141 IKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVES 220
Cdd:TIGR02917 476 LGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG-NEEEAVA 554

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 221 RIEEAMlkckKENNQNdfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFR 300
Cdd:TIGR02917 555 WLEKAA----ELNPQE--IEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL 628


                  ....*...
gi 1063716562 301 KLVPKNHP 308
Cdd:TIGR02917 629 ALQPDSAL 636
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 103-297 5.43e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 38.43  E-value: 5.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 103 SVESKENVTLEEEERALDEHLITH---PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGD 179
Cdd:TIGR00990 301 SPESKADESYEEAARAFEKALDLGklgEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGD 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 180 LDLAKTGFEEILAKDPLRVEAY------HGLLMAYSDAGLDLKevesrieeamlKCKKENNQNDFRDFKLLVAQIRviEG 253
Cdd:TIGR00990 381 PDKAEEDFDKALKLNSEDPDIYyhraqlHFIKGEFAQAGKDYQ-----------KSIDLDPDFIFSHIQLGVTQYK--EG 447

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063716562 254 KHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFD 297
Cdd:TIGR00990 448 SIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFD 491
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
189-297 7.00e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 37.59  E-value: 7.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716562 189 EILAKDPLRVEAYHGLLMAYSDAGLDLKEVESRIEEAMLKCKKENNQNDfRdfkllvAQIRVIEGKHSEALKLYQELVKE 268
Cdd:COG4785    30 LFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYE-R------GVAYDSLGDYDLAIADFDQALEL 102

                          90       100
                  ....*....|....*....|....*....
gi 1063716562 269 EPRDFRPYLCQGIIYTLLKKKDKAEEQFD 297
Cdd:COG4785   103 DPDLAEAYNNRGLAYLLLGDYDAALEDFD 131
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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