NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1063679811|ref|NP_001321395|]
View 

R3H domain protein [Arabidopsis thaliana]

Protein Classification

R3H-assoc and R3H domain-containing protein( domain architecture ID 10621373)

R3H-assoc and R3H domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
R3H-assoc pfam13902
R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, ...
 1-91 1.82e-24

R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, domain-containing proteins. The function is not known.


:

Pssm-ID: 464031  Cd Length: 127  Bit Score: 92.48  E-value: 1.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063679811   1 MELVPRLDAQEIRGlFAPPPWGDDVPPSAFSLTNVGEWDKFRNIDMDKEANIMDSLNRSSVRQKG---SVDGDKIAVLNA 77
Cdd:pfam13902  35 HELVPRLDEIEDDP-DAEPPLPSDFTVLPTHPENAQLWDDFRNLDEDEQERILASLEQSEKKRKKhrvSGEDDRESALAR 113

                          90
                  ....*....|....
gi 1063679811  78 WRRIDCRTRDALRR 91
Cdd:pfam13902 114 FQRIDRRLRAALKR 127
R3H super family cl00297
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ...
 108-152 4.39e-04

R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


The actual alignment was detected with superfamily member cd02642:

Pssm-ID: 469711  Cd Length: 63  Bit Score: 37.20  E-value: 4.39e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1063679811 108 FIEEGGEgDVLELKVQDPFHRLLLHGVCEYHNLVSTTATEQIGRI 152
Cdd:cd02642    15 FIKDSTR-QSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGGKCV 58
 
Name Accession Description Interval E-value
R3H-assoc pfam13902
R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, ...
 1-91 1.82e-24

R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, domain-containing proteins. The function is not known.


Pssm-ID: 464031  Cd Length: 127  Bit Score: 92.48  E-value: 1.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063679811   1 MELVPRLDAQEIRGlFAPPPWGDDVPPSAFSLTNVGEWDKFRNIDMDKEANIMDSLNRSSVRQKG---SVDGDKIAVLNA 77
Cdd:pfam13902  35 HELVPRLDEIEDDP-DAEPPLPSDFTVLPTHPENAQLWDDFRNLDEDEQERILASLEQSEKKRKKhrvSGEDDRESALAR 113

                          90
                  ....*....|....
gi 1063679811  78 WRRIDCRTRDALRR 91
Cdd:pfam13902 114 FQRIDRRLRAALKR 127
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 108-152 4.39e-04

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 37.20  E-value: 4.39e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1063679811 108 FIEEGGEgDVLELKVQDPFHRLLLHGVCEYHNLVSTTATEQIGRI 152
Cdd:cd02642    15 FIKDSTR-QSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGGKCV 58
 
Name Accession Description Interval E-value
R3H-assoc pfam13902
R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, ...
 1-91 1.82e-24

R3H-associated N-terminal domain; This family is found at the N-terminus of R3H, pfam01424, domain-containing proteins. The function is not known.


Pssm-ID: 464031  Cd Length: 127  Bit Score: 92.48  E-value: 1.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063679811   1 MELVPRLDAQEIRGlFAPPPWGDDVPPSAFSLTNVGEWDKFRNIDMDKEANIMDSLNRSSVRQKG---SVDGDKIAVLNA 77
Cdd:pfam13902  35 HELVPRLDEIEDDP-DAEPPLPSDFTVLPTHPENAQLWDDFRNLDEDEQERILASLEQSEKKRKKhrvSGEDDRESALAR 113

                          90
                  ....*....|....
gi 1063679811  78 WRRIDCRTRDALRR 91
Cdd:pfam13902 114 FQRIDRRLRAALKR 127
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 108-152 4.39e-04

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 37.20  E-value: 4.39e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1063679811 108 FIEEGGEgDVLELKVQDPFHRLLLHGVCEYHNLVSTTATEQIGRI 152
Cdd:cd02642    15 FIKDSTR-QSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGGKCV 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH