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Conserved domains on  [gi|1063694420|ref|NP_001321509|]
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Mannose-binding lectin superfamily protein [Arabidopsis thaliana]

Protein Classification

jacalin family lectin; zinc metalloproteinase family protein( domain architecture ID 10658524)

jacalin family lectin is a sugar-binding protein containing a jacalin domain| zinc metalloproteinase family protein contains an HEXXH motif characteristic of metallopeptidases; contains a Jacalin-like lectin domain that may bind mono- or oligosaccharides

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 168-300 1.51e-47

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


:

Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 155.47  E-value: 1.51e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  168 GEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQVVTRYHGMKNGDTEEFViDYPNEYLISVEGTYnilpdDNVLVI 247
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEIL-LYPGEYITSVEGTY-----DKSGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420  248 RSLIFKTSKGRISPTYGFVSGTKFVLESQ-GNAIVGFYGRDGGAF-DAIGVYFSP 300
Cdd:smart00915  74 TSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 22-153 6.81e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


:

Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 143.52  E-value: 6.81e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420   22 GKQWDDGaDHDNVAKVYIRGGLEGIQYIKFDYVKDGKtIDASIHGVSGsgfTQTFEIDYQNSEYIVSVDGYYDKSGTMQA 101
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  102 LEFKTNL-KTSEVIGYPKGtTKFSLGGVNGKMVIGFHG-SAGKVLNSIGAYLTT 153
Cdd:smart00915  76 LTFKTNKgRTSPFGGYEGG-TKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 168-300 1.51e-47

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 155.47  E-value: 1.51e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  168 GEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQVVTRYHGMKNGDTEEFViDYPNEYLISVEGTYnilpdDNVLVI 247
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEIL-LYPGEYITSVEGTY-----DKSGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420  248 RSLIFKTSKGRISPTYGFVSGTKFVLESQ-GNAIVGFYGRDGGAF-DAIGVYFSP 300
Cdd:smart00915  74 TSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 168-300 1.55e-45

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 150.50  E-value: 1.55e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 168 GEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQ-VVTRYHGMKNG-DTEEFVIDYPNEYLISVEGTYNILPDDNVL 245
Cdd:pfam01419   1 GASWDDGV-YDGVRKVYVGQGGDGITYIKFEYVKGGGkVEGDEHGKKGLlGPEEFEIDYPDEYITSVEGTYDKVFGSDSE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420 246 VIRSLIFKTSKGRISPTYGFVSGTKFVLESQGNAIVGFYGRDGGAFDAIGVYFSP 300
Cdd:pfam01419  80 VITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 168-299 2.10e-44

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 147.71  E-value: 2.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 168 GEPWDDGSNYDGVKKISVTYISTLIRSINVDYEKDGQ-VVTRYHGMKNGDTEEFVIDYPNEYLISVEGTYNILPDDNVlv 246
Cdd:cd09612     1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQhVVGPWHGGGGGTPEEIVLDYPDEYITSVSGTYGPVSGSNV-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063694420 247 IRSLIFKTSKgRISPTYGFVSGTKFVLESQGNAIVGFYGRDGGAFDAIGVYFS 299
Cdd:cd09612    79 ITSLTFKTNK-RTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 22-153 6.81e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 143.52  E-value: 6.81e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420   22 GKQWDDGaDHDNVAKVYIRGGLEGIQYIKFDYVKDGKtIDASIHGVSGsgfTQTFEIDYQNSEYIVSVDGYYDKSGTMQA 101
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  102 LEFKTNL-KTSEVIGYPKGtTKFSLGGVNGKMVIGFHG-SAGKVLNSIGAYLTT 153
Cdd:smart00915  76 LTFKTNKgRTSPFGGYEGG-TKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 22-153 5.07e-40

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 136.25  E-value: 5.07e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  22 GKQWDDGaDHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGFTQTFEIDYQNsEYIVSVDGYYDK-----S 96
Cdd:pfam01419   1 GASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPD-EYITSVEGTYDKvfgsdS 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063694420  97 GTMQALEFKTNL-KTSEVIGYPKGtTKFSLgGVNGKMVIGFHGSAGKVLNSIGAYLTT 153
Cdd:pfam01419  79 EVITSLTFKTNKgRTSPFFGTPSG-TKFSL-EVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 22-152 5.79e-34

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 120.36  E-value: 5.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  22 GKQWDDGADHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGfTQTFEIDYqNSEYIVSVDGYYDK---SGT 98
Cdd:cd09612     1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT-PEEIVLDY-PDEYITSVSGTYGPvsgSNV 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  99 MQALEFKTNLKTSEVIGYPKGtTKFSLgGVNGKMVIGFHGSAGKVLNSIGAYLT 152
Cdd:cd09612    79 ITSLTFKTNKRTYGPFGVESG-TPFSL-PVEGGKIVGFHGRSGDYLDAIGVYVS 130
PLN02193 PLN02193
nitrile-specifier protein
 11-158 5.20e-23

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 98.49  E-value: 5.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  11 AQKLDAIGGKGGKQWDDGAdHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGFTQTFEIDyqNSEYIVSVD 90
Cdd:PLN02193    2 AQKLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID--ADDYIVYVE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  91 GYYDKSGTMQA-----LEFKT-NLKTSEVIGYPKGtTKFSLGGvnGKMViGFHGSAGKVLNSIGAYLTTAPPTK 158
Cdd:PLN02193   79 GYREKVNDMTSemitfLSFKTyKGKTSHPIEKRPG-VKFVLQG--GKIV-GFHGRSTDVLHSLGAYISLPSTPK 148
PLN02193 PLN02193
nitrile-specifier protein
 163-299 1.38e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 79.61  E-value: 1.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 163 GGLTGgEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQVVT-RYHGMKNG-DTEEFVIDyPNEYLISVEGTYNILP 240
Cdd:PLN02193    9 GGETG-DVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVgDEHGKKTElGVEEFEID-ADDYIVYVEGYREKVN 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063694420 241 DDNVLVIRSLIFKTSKGRISPTYGFVSGTKFVLesQGNAIVGFYGRDGGAFDAIGVYFS 299
Cdd:PLN02193   86 DMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIS 142
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 168-300 1.51e-47

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 155.47  E-value: 1.51e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  168 GEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQVVTRYHGMKNGDTEEFViDYPNEYLISVEGTYnilpdDNVLVI 247
Cdd:smart00915   1 GTEWDDGA-FDGVRKIYVGQGGEGIKSIQFDYDKGGKVWGDEHGGKGGTGEEIL-LYPGEYITSVEGTY-----DKSGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420  248 RSLIFKTSKGRISPTYGFVSGTKFVLESQ-GNAIVGFYGRDGGAF-DAIGVYFSP 300
Cdd:smart00915  74 TSLTFKTNKGRTSPFGGYEGGTKFVLESKeGKKIVGFHGRSSGDGlDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 168-300 1.55e-45

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 150.50  E-value: 1.55e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 168 GEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQ-VVTRYHGMKNG-DTEEFVIDYPNEYLISVEGTYNILPDDNVL 245
Cdd:pfam01419   1 GASWDDGV-YDGVRKVYVGQGGDGITYIKFEYVKGGGkVEGDEHGKKGLlGPEEFEIDYPDEYITSVEGTYDKVFGSDSE 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420 246 VIRSLIFKTSKGRISPTYGFVSGTKFVLESQGNAIVGFYGRDGGAFDAIGVYFSP 300
Cdd:pfam01419  80 VITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 168-299 2.10e-44

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 147.71  E-value: 2.10e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 168 GEPWDDGSNYDGVKKISVTYISTLIRSINVDYEKDGQ-VVTRYHGMKNGDTEEFVIDYPNEYLISVEGTYNILPDDNVlv 246
Cdd:cd09612     1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQhVVGPWHGGGGGTPEEIVLDYPDEYITSVSGTYGPVSGSNV-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063694420 247 IRSLIFKTSKgRISPTYGFVSGTKFVLESQGNAIVGFYGRDGGAFDAIGVYFS 299
Cdd:cd09612    79 ITSLTFKTNK-RTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 22-153 6.81e-43

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 143.52  E-value: 6.81e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420   22 GKQWDDGaDHDNVAKVYIRGGLEGIQYIKFDYVKDGKtIDASIHGVSGsgfTQTFEIDYQNSEYIVSVDGYYDKSGTMQA 101
Cdd:smart00915   1 GTEWDDG-AFDGVRKIYVGQGGEGIKSIQFDYDKGGK-VWGDEHGGKG---GTGEEILLYPGEYITSVEGTYDKSGVITS 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  102 LEFKTNL-KTSEVIGYPKGtTKFSLGGVNGKMVIGFHG-SAGKVLNSIGAYLTT 153
Cdd:smart00915  76 LTFKTNKgRTSPFGGYEGG-TKFVLESKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 22-153 5.07e-40

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 136.25  E-value: 5.07e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  22 GKQWDDGaDHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGFTQTFEIDYQNsEYIVSVDGYYDK-----S 96
Cdd:pfam01419   1 GASWDDG-VYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPD-EYITSVEGTYDKvfgsdS 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063694420  97 GTMQALEFKTNL-KTSEVIGYPKGtTKFSLgGVNGKMVIGFHGSAGKVLNSIGAYLTT 153
Cdd:pfam01419  79 EVITSLTFKTNKgRTSPFFGTPSG-TKFSL-EVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 22-152 5.79e-34

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 120.36  E-value: 5.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  22 GKQWDDGADHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGfTQTFEIDYqNSEYIVSVDGYYDK---SGT 98
Cdd:cd09612     1 GSAWDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGGGGGT-PEEIVLDY-PDEYITSVSGTYGPvsgSNV 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  99 MQALEFKTNLKTSEVIGYPKGtTKFSLgGVNGKMVIGFHGSAGKVLNSIGAYLT 152
Cdd:cd09612    79 ITSLTFKTNKRTYGPFGVESG-TPFSL-PVEGGKIVGFHGRSGDYLDAIGVYVS 130
PLN02193 PLN02193
nitrile-specifier protein
 11-158 5.20e-23

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 98.49  E-value: 5.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  11 AQKLDAIGGKGGKQWDDGAdHDNVAKVYIRGGLEGIQYIKFDYVKDGKTIDASIHGVSGSGFTQTFEIDyqNSEYIVSVD 90
Cdd:PLN02193    2 AQKLEAKGGETGDVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID--ADDYIVYVE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063694420  91 GYYDKSGTMQA-----LEFKT-NLKTSEVIGYPKGtTKFSLGGvnGKMViGFHGSAGKVLNSIGAYLTTAPPTK 158
Cdd:PLN02193   79 GYREKVNDMTSemitfLSFKTyKGKTSHPIEKRPG-VKFVLQG--GKIV-GFHGRSTDVLHSLGAYISLPSTPK 148
PLN02193 PLN02193
nitrile-specifier protein
 163-299 1.38e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 79.61  E-value: 1.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 163 GGLTGgEPWDDGSnYDGVKKISVTYISTLIRSINVDYEKDGQVVT-RYHGMKNG-DTEEFVIDyPNEYLISVEGTYNILP 240
Cdd:PLN02193    9 GGETG-DVWDDGV-YDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVgDEHGKKTElGVEEFEID-ADDYIVYVEGYREKVN 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063694420 241 DDNVLVIRSLIFKTSKGRISPTYGFVSGTKFVLesQGNAIVGFYGRDGGAFDAIGVYFS 299
Cdd:PLN02193   86 DMTSEMITFLSFKTYKGKTSHPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGAYIS 142
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 167-299 1.79e-07

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 49.24  E-value: 1.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 167 GGEPWDDGSNYDG-VKKISVTYISTLIRSINVDYekdGQVVTRYHGMKNGDTEEFVIDyPNEYLISVEGTYNIlpddnvl 245
Cdd:cd09611     4 GGKYFSDVGEGGGpITGIRVSVGNNYIKGIQVRY---GSNWSDVYGGRGGNEQEIVLE-PGESITKVSGSYKI------- 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063694420 246 VIRSLIFKTSKGRiSPTYGFVSGTKFVLE--SQGNAIVGFYGR-DGGAFDAIGVYFS 299
Cdd:cd09611    73 YLHGLVFTTNKGR-YLSFGKLRGRSFNATppPSNYVLRGISGRyGGLGIKSIGFHWG 128
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 19-153 1.90e-07

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 49.32  E-value: 1.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  19 GKGGKQWDDgADHDNVAKVYIRGGLEgIQYIKFDYVKDGKTIDASiHGVSGSGFTQTFEIdyQNSEYIVSVDGYYdkSGT 98
Cdd:cd09614     1 GFGGSPGSD-FDILTVSAIQLRSGSY-VDQIITDYQDLNGTQNFH-HGGGGGNLSPTLNF--SSGEYITEVTGRS--GDR 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063694420  99 MQALEFKTNLKTSEVIGYPKGTTKFSLGGVNGKMVIGFHGSAGKVLNSIGAYLTT 153
Cdd:cd09614    74 VDQVQFTTNYGGRTLPGGGGGGSAFTWTVPDNQKVIGFAGRSGSYLDQLQVYYLS 128
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 168-299 5.46e-04

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 39.31  E-value: 5.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 168 GEPWDDGSNYD-GVKKISVtYISTLIRSINVDYekDGQVVTRYHGMKNGDTEEFVIDyPNEYL--ISVEGTYNilpdDNV 244
Cdd:cd09302     1 GKPFSDTGGDGaRLTEIRV-RSGGAVDAIRVVL--RDYTDGRHGGNGGPNTSSVFLD-PGEYItiTSVSSGDN----GGG 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063694420 245 LVIRSLIFKTSKGRiSPTYG---FVSGTKFVLESqGNAIVGFYGRDGGAFDAIGVYFS 299
Cdd:cd09302    73 TRIDAIQFTTNKGR-SGTYGttsGALGTEFTVPV-GGEIVGIYGRAGDDVDAFGFILS 128
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 167-298 3.82e-03

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 36.61  E-value: 3.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420 167 GGEPWDDgsnYDGVKKISVTYIS-TLIRSINVDYEKDGQVVTRYHGMKNGDTEEFVIDYPNEYLISVEGTYNILPDdnvl 245
Cdd:cd09614     3 GGSPGSD---FDILTVSAIQLRSgSYVDQIITDYQDLNGTQNFHHGGGGGNLSPTLNFSSGEYITEVTGRSGDRVD---- 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063694420 246 virSLIFKTSKGRISPTYGFVSGTKFVLESQGNAIV-GFYGRDGGAFDAIGVYF 298
Cdd:cd09614    76 ---QVQFTTNYGGRTLPGGGGGGSAFTWTVPDNQKViGFAGRSGSYLDQLQVYY 126
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 22-152 5.03e-03

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 36.61  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063694420  22 GKQWDDGADHDNVAK---VYIRGGLEGIQyIKFDYVKDGKtidasihgVSGSGFTQTFEIDYQNSEYIVSVDGYYDKSGT 98
Cdd:cd09302     1 GKPFSDTGGDGARLTeirVRSGGAVDAIR-VVLRDYTDGR--------HGGNGGPNTSSVFLDPGEYITITSVSSGDNGG 71

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1063694420  99 MQ---ALEFKTNLKTSEVIGYPKGTTKFSLGGVNGKMVIGFHGSAGKVLNSIGAYLT 152
Cdd:cd09302    72 GTridAIQFTTNKGRSGTYGTTSGALGTEFTVPVGGEIVGIYGRAGDDVDAFGFILS 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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