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Conserved domains on  [gi|1063680071|ref|NP_001322270|]
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Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

Protein Classification

HAT repeat-containing protein; tetratricopeptide repeat protein; tetratricopeptide repeat protein( domain architecture ID 13418488)

HAT (Half-A-TPR) repeat-containing protein similar to Candida albicans pre-mRNA-splicing factor CLF1 that is involved in pre-mRNA splicing and cell cycle progression; tetratricopeptide repeat (TPR) protein similar to Xenopus ER membrane protein complex subunit 2 (EMC2); tetratricopeptide repeat (TPR) protein similar to Xenopus ER membrane protein complex subunit 2 (EMC2)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA14 super family cl34906
Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and ...
 60-249 7.22e-11

Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification];


The actual alignment was detected with superfamily member COG5107:

Pssm-ID: 227438 [Multi-domain]  Cd Length: 660  Bit Score: 65.81  E-value: 7.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071  60 SATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETEriAQDNIAKIRKVYDAFLAEFPLCYGYW 139
Cdd:COG5107     2 SSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLE--TQESMDAEREMYEQLSSPFPIMEHAW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 140 KKFADHEARVGAMDKVVEVYERAVLGVtYSVDIWLHYCTFA--INTYGDPE---TIRRLFERALVYVGTDFLSSPLWDKY 214
Cdd:COG5107    80 RLYMSGELARKDFRSVESLFGRCLKKS-LNLDLWMLYLEYIrrVNNLITGQkrfKIYEAYEFVLGCAIFEPQSENYWDEY 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063680071 215 IEY-EYM--------QQDWSRVALIYTRILENPIQNLDRYFSSF 249
Cdd:COG5107   159 GLFlEYIeelgkweeQQRIDKIRNGYMRALQTPMGNLEKLWKDY 202
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 375-407 3.93e-04

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


:

Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 38.30  E-value: 3.93e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1063680071  375 GDFNKVVKLYERCVVTCANYPEYWIRYVTNMEA 407
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 372-493 3.96e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 372 ERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFvKKQPEIHLFAARLKEQNGDIAGARA 451
Cdd:COG4783    15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD-PDEPEARLNLGLALLKAGDYDEALA 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1063680071 452 AYQLVHsEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIA 493
Cdd:COG4783    94 LLEKAL-KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
 
Name Accession Description Interval E-value
RNA14 COG5107
Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and ...
 60-249 7.22e-11

Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification];


Pssm-ID: 227438 [Multi-domain]  Cd Length: 660  Bit Score: 65.81  E-value: 7.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071  60 SATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETEriAQDNIAKIRKVYDAFLAEFPLCYGYW 139
Cdd:COG5107     2 SSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLE--TQESMDAEREMYEQLSSPFPIMEHAW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 140 KKFADHEARVGAMDKVVEVYERAVLGVtYSVDIWLHYCTFA--INTYGDPE---TIRRLFERALVYVGTDFLSSPLWDKY 214
Cdd:COG5107    80 RLYMSGELARKDFRSVESLFGRCLKKS-LNLDLWMLYLEYIrrVNNLITGQkrfKIYEAYEFVLGCAIFEPQSENYWDEY 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063680071 215 IEY-EYM--------QQDWSRVALIYTRILENPIQNLDRYFSSF 249
Cdd:COG5107   159 GLFlEYIeelgkweeQQRIDKIRNGYMRALQTPMGNLEKLWKDY 202
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 375-407 3.93e-04

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 38.30  E-value: 3.93e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1063680071  375 GDFNKVVKLYERCVVTCANYPEYWIRYVTNMEA 407
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 372-493 3.96e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 372 ERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFvKKQPEIHLFAARLKEQNGDIAGARA 451
Cdd:COG4783    15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD-PDEPEARLNLGLALLKAGDYDEALA 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1063680071 452 AYQLVHsEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIA 493
Cdd:COG4783    94 LLEKAL-KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 185-218 1.93e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.37  E-value: 1.93e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1063680071  185 GDPETIRRLFERALVYVGtdfLSSPLWDKYIEYE 218
Cdd:smart00386   1 GDIERARKIYERALEKFP---KSVELWLKYAEFE 31
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 409-541 1.93e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 409 GSADLAENALARATQVF---VKKQPEiHLFA----ARLKEQNGDIAGARAAYQLVhSEISPGLLEAVIKHANMEYRLGNL 481
Cdd:TIGR02917 472 GAIYLGKGDLAKAREAFekaLSIEPD-FFPAaanlARIDIQEGNPDDAIQRFEKV-LTIDPKNLRAILALAGLYLRTGNE 549

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 482 DDAFSLYEQVIAVEKGKEHstiLPLLYAQYsrfsYLVSRDAEKARRIIVEALDhVQPSKP 541
Cdd:TIGR02917 550 EEAVAWLEKAAELNPQEIE---PALALAQY----YLGKGQLKKALAILNEAAD-AAPDSP 601
 
Name Accession Description Interval E-value
RNA14 COG5107
Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and ...
 60-249 7.22e-11

Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification];


Pssm-ID: 227438 [Multi-domain]  Cd Length: 660  Bit Score: 65.81  E-value: 7.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071  60 SATDNVAVTAPAAEHGDNTGSTLSTEEERLWNIVRANSLEFNAWTALIDETEriAQDNIAKIRKVYDAFLAEFPLCYGYW 139
Cdd:COG5107     2 SSSTTPDLLYPSADKVAEPSDNIHGDELRLRERIKDNPTNILSYFQLIQYLE--TQESMDAEREMYEQLSSPFPIMEHAW 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 140 KKFADHEARVGAMDKVVEVYERAVLGVtYSVDIWLHYCTFA--INTYGDPE---TIRRLFERALVYVGTDFLSSPLWDKY 214
Cdd:COG5107    80 RLYMSGELARKDFRSVESLFGRCLKKS-LNLDLWMLYLEYIrrVNNLITGQkrfKIYEAYEFVLGCAIFEPQSENYWDEY 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063680071 215 IEY-EYM--------QQDWSRVALIYTRILENPIQNLDRYFSSF 249
Cdd:COG5107   159 GLFlEYIeelgkweeQQRIDKIRNGYMRALQTPMGNLEKLWKDY 202
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 375-407 3.93e-04

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 38.30  E-value: 3.93e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1063680071  375 GDFNKVVKLYERCVVTCANYPEYWIRYVTNMEA 407
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 372-493 3.96e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 3.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 372 ERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVFvKKQPEIHLFAARLKEQNGDIAGARA 451
Cdd:COG4783    15 LLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD-PDEPEARLNLGLALLKAGDYDEALA 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1063680071 452 AYQLVHsEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIA 493
Cdd:COG4783    94 LLEKAL-KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 372-568 1.15e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.64  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 372 ERDGDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVfVKKQPEIHLFAARLKEQNGDIAGARA 451
Cdd:COG2956    53 RRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAEIYEQEGDWEKAIE 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 452 AYQLVhSEISPGLLEAVIKHANMEYRLGNLDDAFSLYEQVIAVEKGKEHSTilpLLYAQYsrfsYLVSRDAEKARRIIVE 531
Cdd:COG2956   132 VLERL-LKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL---LLLAEL----YLEQGDYEEAIAALER 203

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1063680071 532 ALDHVQPSKPLMEALIH-FEAIQPPPREIDYLEPLVEK 568
Cdd:COG2956   204 ALEQDPDYLPALPRLAElYEKLGDPEEALELLRKALEL 241
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 405-495 1.69e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 405 MEASGSADLAENALARATQVFVKKQPEIHLFAARLKEQnGDIAGARAAYQLVHsEISPGLLEAVIKHANMEYRLGNLDDA 484
Cdd:COG3914    88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL-GRLEEALAALRRAL-ALNPDFAEAYLNLGEALRRLGRLEEA 165

                          90
                  ....*....|.
gi 1063680071 485 FSLYEQVIAVE 495
Cdd:COG3914   166 IAALRRALELD 176
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 185-218 1.93e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 36.37  E-value: 1.93e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1063680071  185 GDPETIRRLFERALVYVGtdfLSSPLWDKYIEYE 218
Cdd:smart00386   1 GDIERARKIYERALEKFP---KSVELWLKYAEFE 31
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 409-541 1.93e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 409 GSADLAENALARATQVF---VKKQPEiHLFA----ARLKEQNGDIAGARAAYQLVhSEISPGLLEAVIKHANMEYRLGNL 481
Cdd:TIGR02917 472 GAIYLGKGDLAKAREAFekaLSIEPD-FFPAaanlARIDIQEGNPDDAIQRFEKV-LTIDPKNLRAILALAGLYLRTGNE 549

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 482 DDAFSLYEQVIAVEKGKEHstiLPLLYAQYsrfsYLVSRDAEKARRIIVEALDhVQPSKP 541
Cdd:TIGR02917 550 EEAVAWLEKAAELNPQEIE---PALALAQY----YLGKGQLKKALAILNEAAD-AAPDSP 601
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 117-146 2.70e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 35.99  E-value: 2.70e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 1063680071  117 NIAKIRKVYDAFLAEFPLCYGYWKKFADHE 146
Cdd:smart00386   2 DIERARKIYERALEKFPKSVELWLKYAEFE 31
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 375-472 3.83e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 3.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 375 GDFNKVVKLYERCVVTCANYPEYWIRYVTNMEASGSADLAENALARATQVfVKKQPEIHLFAARLKEQNGDIAGARAAYQ 454
Cdd:COG4235    31 GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL-DPDNPEALYLLGLAAFQQGDYAEAIAAWQ 109

                          90
                  ....*....|....*...
gi 1063680071 455 LVHSEISPGLLEAVIKHA 472
Cdd:COG4235   110 KLLALLPADAPARLLEAS 127
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 393-494 5.46e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 5.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 393 NYPEYWIRYVTNMEASGSADLAENALARATQvFVKKQPEIHLFAARLKEQNGDIAGARAAYQLVHsEISPGLLEAVIKHA 472
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALR-LDPDNADALLDLAEALLAAGDTEEAEELLERAL-ALDPDNPEALYLLG 92

                          90       100
                  ....*....|....*....|..
gi 1063680071 473 NMEYRLGNLDDAFSLYEQVIAV 494
Cdd:COG4235    93 LAAFQQGDYAEAIAAWQKLLAL 114
HAT smart00386
HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and ...
 150-182 6.67e-03

HAT (Half-A-TPR) repeats; Present in several RNA-binding proteins. Structurally and sequentially thought to be similar to TPRs.


Pssm-ID: 214642 [Multi-domain]  Cd Length: 33  Bit Score: 34.83  E-value: 6.67e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1063680071  150 GAMDKVVEVYERAVLGVTYSVDIWLHYCTFAIN 182
Cdd:smart00386   1 GDIERARKIYERALEKFPKSVELWLKYAEFEER 33
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 409-541 9.81e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.56  E-value: 9.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063680071 409 GSADLAENALARATQVFVK------KQPEIHLFAARLKEQNGDIAGARAAYQLVHsEISPGLLEAVIKHANMEYRLGNLD 482
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEaleldpETVEAHLALGNLYRRRGEYDRAIRIHQKLL-ERDPDRAEALLELAQDYLKAGLLD 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063680071 483 DAFSLYEQviAVEKGKEHSTILPLLYAQYSRfsylvSRDAEKARRiIVEALDHVQPSKP 541
Cdd:COG2956    94 RAEELLEK--LLELDPDDAEALRLLAEIYEQ-----EGDWEKAIE-VLERLLKLGPENA 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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