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Conserved domains on  [gi|1063696966|ref|NP_001322698|]
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vacuolar H+-pyrophosphatase 2 [Arabidopsis thaliana]

Protein Classification

sodium/proton-translocating pyrophosphatase; MFS transporter( domain architecture ID 10010753)

sodium/proton-translocating pyrophosphatase such as K(+)-stimulated pyrophosphate-energized sodium pump and K(+)-insensitive pyrophosphate-energized proton pump, which utilize the energy of pyrophosphate hydrolysis as the driving force for sodium/proton movement across the membrane| major facilitator superfamily (MFS) transporter facilitates the transport across cytoplasmic or internal membranes of one or more from a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
73-802 0e+00

H(+) -translocating inorganic pyrophosphatase


:

Pssm-ID: 177916  Cd Length: 730  Bit Score: 1401.85  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  73 TVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILCIYLFRSLTPQQEAAGLGR 152
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 153 AMSAYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVW 232
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 233 LGVGSPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 312
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 313 ARGADLFESIAAEIISAMILGGTMAKKCKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKSPVEDPMAVLQKG 392
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 393 YSLTIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGV 472
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 473 SLGLESTALPVLTISVAIISAYWLGNTSGLVDENGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 552
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 553 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAW 632
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 633 ACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLVFRILGYYTGQPLL 712
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 713 GAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 792
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 1063696966 793 ITLVMAPVFL 802
Cdd:PLN02277  721 ITLVMAPMFL 730
 
Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
73-802 0e+00

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 177916  Cd Length: 730  Bit Score: 1401.85  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  73 TVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILCIYLFRSLTPQQEAAGLGR 152
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 153 AMSAYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVW 232
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 233 LGVGSPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 312
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 313 ARGADLFESIAAEIISAMILGGTMAKKCKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKSPVEDPMAVLQKG 392
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 393 YSLTIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGV 472
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 473 SLGLESTALPVLTISVAIISAYWLGNTSGLVDENGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 552
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 553 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAW 632
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 633 ACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLVFRILGYYTGQPLL 712
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 713 GAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 792
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 1063696966 793 ITLVMAPVFL 802
Cdd:PLN02277  721 ITLVMAPMFL 730
H_PPase pfam03030
Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved ...
76-797 0e+00

Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved in establishing the H+ electrochemical potential difference between the vacuole lumen and the cell cytosol. Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of photo-trophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organizms as disparate as thermophilic Archaea and parasitic protists.


Pssm-ID: 427106  Cd Length: 663  Bit Score: 916.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  76 IISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILciylfrsltpqqeaaglgrAMS 155
Cdd:pfam03030   1 LLALLFALYLARWVLKQPAGTEKMQEIAGAIQEGAMAFLKRQYKTLAIFAVVIAVLLF-------------------LLL 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 156 AYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFyvwlgv 235
Cdd:pfam03030  62 GLLTAVAFLVGALFSALAGYIGMRVATRANVRTANAARKGLGKALRVAFRGGAVMGLLVVGLGLLGLSLLYLIF------ 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 236 gsPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARG 315
Cdd:pfam03030 136 --GDGLDDETAPEALVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMG 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 316 ADLFESIAAEIISAMILGGTMAKkckIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKspvEDPMAVLQKGYSL 395
Cdd:pfam03030 214 ADLFESYVVTIVAAMVLGALAAS---PELGVKLVLFPLLIAAVGIIASIIGTFFVRTKANPKGK---EDPMKALNRGLWV 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 396 TIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLG 475
Cdd:pfam03030 288 SAILSIVLIFFASYLLLGAGGAGFGWWGLFLAILIGLVAGALIGLITEYYTSTSYRPVREIAEASETGAATNIISGLAVG 367
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 476 LESTALPVLTISVAIISAYWLGntsglvdengiptgGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPES 555
Cdd:pfam03030 368 MESTALPVLVIAAAILIAYLLA--------------GLYGIALAAVGMLSTAGITLAVDAYGPIADNAGGIAEMSGLPEE 433
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 556 VREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAWACA 635
Cdd:pfam03030 434 VREITDALDAVGNTTKAIGKGFAIGSAALAALALFAAYIEEVGAVLGGPLLVLDLLNPPVLVGLLIGGMLPFLFSALTMQ 513
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 636 AVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLvfrilgyytgqpLLGAK 715
Cdd:pfam03030 514 AVGRAAGRMVEEVRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIVVGF------------LLGPE 581
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 716 VVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITL 795
Cdd:pfam03030 582 ALGGLLAGATVSGVLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMSIVSL 661

                  ..
gi 1063696966 796 VM 797
Cdd:pfam03030 662 VF 663
OVP1 COG3808
Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];
89-802 0e+00

Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];


Pssm-ID: 443021  Cd Length: 660  Bit Score: 858.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  89 VLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTIskmAILLAFVILCIYLFRSltpqqeaaglgraMSAYITVAAFLLGAL 168
Cdd:COG3808     1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTL---AIFAVVIAVLLALLLG-------------GGGWLTAIAFLIGAV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 169 CSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVWLgvgspgsmnvTDLPL 248
Cdd:COG3808    65 FSALAGYIGMRVATRANVRTANAARKGLNKALKVAFRGGAVMGLLVVGLGLLGLSLLYLIFGGFL----------ETAPE 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 249 LLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 328
Cdd:COG3808   135 VLVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVVTIVA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 329 AMILGGTMAkkcKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDAsvkspveDPMAVLQKGYSLTIILAVITFGAST 408
Cdd:COG3808   215 AMVLGALAF---GAALGVALVLLPLLIAAVGIIASIIGIFFVRTKEGA-------NPMKALNRGTYVTAVLSAVATYFVT 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 409 RWLLYTEQAPsaWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLGLESTALPVLTISV 488
Cdd:COG3808   285 YLLLPGSGFG--WLGLFLAVLIGLVAGALIGLITEYYTSTEYRPVREIAEASETGPATNIISGLAVGMESTALPVLVIAA 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 489 AIISAYWLGntsglvdeNGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDLLDAVGN 568
Cdd:COG3808   363 AILVAYLLA--------GGGFAPGLYGIALAAVGMLSTTGITVAVDAYGPIADNAGGIAEMSGLPPEVREITDALDAVGN 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 569 TTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKE-VDIAIPEVFVGGLLGAMLIFLFSAWACAAVGRTAQEVVNE 647
Cdd:COG3808   435 TTKAITKGFAIGSAALAALALFAAYIEEVGIALGEALLLsLDLLNPPVLVGLFIGGMLPFLFSALAMQAVGRAAGAMVEE 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 648 VRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLvfrilgyytgqpLLGAKVVASMLMFATVC 727
Cdd:COG3808   515 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGF------------LLGPEALGGLLAGAIVS 582
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063696966 728 GILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPVFL 802
Cdd:COG3808   583 GVLLAIFMANAGGAWDNAKKYIEDGNLGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMNIVSLVIAPLFV 657
V_PPase TIGR01104
vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases ...
69-801 0e+00

vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases from eukaryotes (predominantly plants), archaea and bacteria. It is an integral membrane protein and is suggested to have about 15 membrane spanning domains. Proton translocating inorganic pyrophosphatase, like H(+)-ATPase, acidifies the vacuoles and is pivotal to the vacuolar secondary active transport systems in plants. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273444  Cd Length: 695  Bit Score: 596.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  69 VFVFTVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTIskmAILLAFVILCIYLFrsltpqqeaA 148
Cdd:TIGR01104   3 ILIPVCAVIGIAYAVLQWVWVSRVKLGTAKMAEIQQAISEGATAFLFTEYKYV---AVFMVAFAVLIFVF---------L 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 149 GLGRAMSAYITVAaFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYST 228
Cdd:TIGR01104  71 GSREGFSDFSTVA-FLLGAVTSLLAGYLGMKIATYANARTTLEARKGVGKALIVAFRSGAVMGFLLAGLGLLVLYITILV 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 229 FYVWLGVGSPGSMNVtdlpllLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNV 308
Cdd:TIGR01104 150 FKIYYGDDWEGLFEP------ITGYGFGASSMALFGRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNV 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 309 GDCAARGADLFESIAAEIISAMILGGTMAkkckIEDPSGFI--LFPLVVHSfdliisSIGILSIKGTRDASVKsPVEDPM 386
Cdd:TIGR01104 224 GDIAGMGADLFESYAESSCAALVLASISS----FGLPHDFTamLYPLALSS------VGILVCLLTTLFVKIK-PVKEIE 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 387 AVLQKGYSLTIILAVITFGASTRWLLYT--------EQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLAL 458
Cdd:TIGR01104 293 PALKKQLIISTVLMTVGVAVISWVALPTgftifnfgTQKEVSNWQLFLCVAVGLWAGLLIGFVTEYYTSNAYSPVQDVAD 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 459 ASSTGHGTNIIAGVSLGLESTALPVLTISVAIISAYWLgntsglvdengiptGGLFGTAVATMGMLSTAAYVLTMDMFGP 538
Cdd:TIGR01104 373 SCRTGAATNVIFGLALGYKSVIIPIFAIAASIIVSFSF--------------AGMYGIAMAALGMLSTAGTGLAIDAYGP 438
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 539 IADNAGGIVEMSQQPESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEvsafanVSFKEVDIAIPEVFVG 618
Cdd:TIGR01104 439 ISDNAGGIAEMAGLPHRVRERTDALDAVGNTTAAIGKGFAIGSAALVALALFGAFVSR------AVITTVDVLTPKVFIG 512
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 619 GLLGAMLIFLFSAWACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGL 698
Cdd:TIGR01104 513 LFVGAMLPYWFSSMTMKSVGRAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGLLVMLTPLIVGF 592
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 699 VFrilgyytgqpllGAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGA-----LGGKGSEAHKAAVTGDTVGD 773
Cdd:TIGR01104 593 LF------------GVETLSGVLAGVLVSGVQIAISASNTGGAWDNAKKYIEAGSeharsLGPKGSEAHKAAVIGDTVGD 660
                         730       740
                  ....*....|....*....|....*...
gi 1063696966 774 PFKDTAGPSIHVLIKMLATITLVMAPVF 801
Cdd:TIGR01104 661 PLKDTSGPSLNILIKLMAVESLVFAPFF 688
 
Name Accession Description Interval E-value
PLN02277 PLN02277
H(+) -translocating inorganic pyrophosphatase
73-802 0e+00

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 177916  Cd Length: 730  Bit Score: 1401.85  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  73 TVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILCIYLFRSLTPQQEAAGLGR 152
Cdd:PLN02277    1 TVCIISLLFSLYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYGTISKMAVVLAFVILGIYLFRSLTPQQEAAGLGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 153 AMSAYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVW 232
Cdd:PLN02277   81 ATSAYITVASFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMTVLGVAILYATFYVW 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 233 LGVGSPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 312
Cdd:PLN02277  161 LGVDSPGGMKVTDLPLLLVGYGFGASFVALFAQLGGGIYTKAADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 313 ARGADLFESIAAEIISAMILGGTMAKKCKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKSPVEDPMAVLQKG 392
Cdd:PLN02277  241 ARGADLFESIAAEIISAMILGGTMAKRCKIEDPSGFILFPLVVHSFDLVVSSIGILSIKGTRDSSVKSPVEDPMAVLQKG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 393 YSLTIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGV 472
Cdd:PLN02277  321 YSVTIILAVVTFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYAFVWISQYYTDYKYEPVRTLALASTTGHGTNIIAGV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 473 SLGLESTALPVLTISVAIISAYWLGNTSGLVDENGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 552
Cdd:PLN02277  401 SLGLESTALPVLVISVAIISAYWLGNTSGLVDENGNPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 553 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAW 632
Cdd:PLN02277  481 PESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFAGVPFKEVDIAIPEVFVGGLLGSMLIFLFSAW 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 633 ACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLVFRILGYYTGQPLL 712
Cdd:PLN02277  561 ACAAVGRTAQEVVNEVRRQFAERPGIMDYKEKPDYGRCVAIVASAALREMIKPGALAVISPIVVGLVFRILGYATGQPLL 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 713 GAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 792
Cdd:PLN02277  641 GAKVVAGMLMFATVSGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLAT 720
                         730
                  ....*....|
gi 1063696966 793 ITLVMAPVFL 802
Cdd:PLN02277  721 ITLVMAPMFL 730
H_PPase pfam03030
Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved ...
76-797 0e+00

Inorganic H+ pyrophosphatase; The H+ pyrophosphatase is an transmembrane proton pump involved in establishing the H+ electrochemical potential difference between the vacuole lumen and the cell cytosol. Vacuolar-type H(+)-translocating inorganic pyrophosphatases have long been considered to be restricted to plants and to a few species of photo-trophic bacteria. However, in recent investigations, these pyrophosphatases have been found in organizms as disparate as thermophilic Archaea and parasitic protists.


Pssm-ID: 427106  Cd Length: 663  Bit Score: 916.43  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  76 IISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILciylfrsltpqqeaaglgrAMS 155
Cdd:pfam03030   1 LLALLFALYLARWVLKQPAGTEKMQEIAGAIQEGAMAFLKRQYKTLAIFAVVIAVLLF-------------------LLL 61
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 156 AYITVAAFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFyvwlgv 235
Cdd:pfam03030  62 GLLTAVAFLVGALFSALAGYIGMRVATRANVRTANAARKGLGKALRVAFRGGAVMGLLVVGLGLLGLSLLYLIF------ 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 236 gsPGSMNVTDLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARG 315
Cdd:pfam03030 136 --GDGLDDETAPEALVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMG 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 316 ADLFESIAAEIISAMILGGTMAKkckIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDASVKspvEDPMAVLQKGYSL 395
Cdd:pfam03030 214 ADLFESYVVTIVAAMVLGALAAS---PELGVKLVLFPLLIAAVGIIASIIGTFFVRTKANPKGK---EDPMKALNRGLWV 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 396 TIILAVITFGASTRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLG 475
Cdd:pfam03030 288 SAILSIVLIFFASYLLLGAGGAGFGWWGLFLAILIGLVAGALIGLITEYYTSTSYRPVREIAEASETGAATNIISGLAVG 367
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 476 LESTALPVLTISVAIISAYWLGntsglvdengiptgGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPES 555
Cdd:pfam03030 368 MESTALPVLVIAAAILIAYLLA--------------GLYGIALAAVGMLSTAGITLAVDAYGPIADNAGGIAEMSGLPEE 433
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 556 VREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAWACA 635
Cdd:pfam03030 434 VREITDALDAVGNTTKAIGKGFAIGSAALAALALFAAYIEEVGAVLGGPLLVLDLLNPPVLVGLLIGGMLPFLFSALTMQ 513
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 636 AVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLvfrilgyytgqpLLGAK 715
Cdd:pfam03030 514 AVGRAAGRMVEEVRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIVVGF------------LLGPE 581
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 716 VVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITL 795
Cdd:pfam03030 582 ALGGLLAGATVSGVLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMSIVSL 661

                  ..
gi 1063696966 796 VM 797
Cdd:pfam03030 662 VF 663
OVP1 COG3808
Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];
89-802 0e+00

Na+ or H+-translocating membrane pyrophosphatase [Energy production and conversion];


Pssm-ID: 443021  Cd Length: 660  Bit Score: 858.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  89 VLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTIskmAILLAFVILCIYLFRSltpqqeaaglgraMSAYITVAAFLLGAL 168
Cdd:COG3808     1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTL---AIFAVVIAVLLALLLG-------------GGGWLTAIAFLIGAV 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 169 CSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFYVWLgvgspgsmnvTDLPL 248
Cdd:COG3808    65 FSALAGYIGMRVATRANVRTANAARKGLNKALKVAFRGGAVMGLLVVGLGLLGLSLLYLIFGGFL----------ETAPE 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 249 LLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 328
Cdd:COG3808   135 VLVGFGFGASLIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDVAGMGADLFESYVVTIVA 214
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 329 AMILGGTMAkkcKIEDPSGFILFPLVVHSFDLIISSIGILSIKGTRDAsvkspveDPMAVLQKGYSLTIILAVITFGAST 408
Cdd:COG3808   215 AMVLGALAF---GAALGVALVLLPLLIAAVGIIASIIGIFFVRTKEGA-------NPMKALNRGTYVTAVLSAVATYFVT 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 409 RWLLYTEQAPsaWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLGLESTALPVLTISV 488
Cdd:COG3808   285 YLLLPGSGFG--WLGLFLAVLIGLVAGALIGLITEYYTSTEYRPVREIAEASETGPATNIISGLAVGMESTALPVLVIAA 362
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 489 AIISAYWLGntsglvdeNGIPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDLLDAVGN 568
Cdd:COG3808   363 AILVAYLLA--------GGGFAPGLYGIALAAVGMLSTTGITVAVDAYGPIADNAGGIAEMSGLPPEVREITDALDAVGN 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 569 TTKATTKGFAIGSAALASFLLFSAYMDEVSAFANVSFKE-VDIAIPEVFVGGLLGAMLIFLFSAWACAAVGRTAQEVVNE 647
Cdd:COG3808   435 TTKAITKGFAIGSAALAALALFAAYIEEVGIALGEALLLsLDLLNPPVLVGLFIGGMLPFLFSALAMQAVGRAAGAMVEE 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 648 VRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLvfrilgyytgqpLLGAKVVASMLMFATVC 727
Cdd:COG3808   515 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGF------------LLGPEALGGLLAGAIVS 582
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063696966 728 GILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPVFL 802
Cdd:COG3808   583 GVLLAIFMANAGGAWDNAKKYIEDGNLGGKGSEAHKAAVVGDTVGDPFKDTAGPSLNILIKLMNIVSLVIAPLFV 657
hppA PRK00733
membrane-bound proton-translocating pyrophosphatase; Validated
89-801 0e+00

membrane-bound proton-translocating pyrophosphatase; Validated


Pssm-ID: 234827 [Multi-domain]  Cd Length: 666  Bit Score: 826.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  89 VLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTISKMAILLAFVILCIYLFRSLtpqqeaaglgramsAYITVAAFLLGAL 168
Cdd:PRK00733    1 VLKQPAGTERMQEIAGAIQEGAMAYLKRQYKTIAIFGVVVAVLLFLPAGGLFL--------------GWLTAVAFLVGAV 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 169 CSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYSTFyvwlgvgsPGSMNVTDLPL 248
Cdd:PRK00733   67 FSALAGYIGMRVATRANVRTAQAARKGLGKALKVAFRGGAVMGLLVVGLGLLGVAGLYLVF--------GLGANPDDAPD 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 249 LLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIAAEIIS 328
Cdd:PRK00733  139 ALVGFGFGASLIALFARVGGGIFTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMGADLFESYAVTIVA 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 329 AMILGGTMAkkcKIEDPSGFILFPLVVHSFDLIISSIGILSIKGtrdasvkSPVEDPMAVLQKGYSLTIILAVITFGAST 408
Cdd:PRK00733  219 AMVLGAAAA---DAAFGVAGVLFPLLIAAVGIIASIIGIFFVRL-------GKGGNPMKALNRGLIVTAVLSIVLTYFAT 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 409 RWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLGLESTALPVLTISV 488
Cdd:PRK00733  289 YWLLGDGADGFTWLNLFGAVLIGLVVGALIGLITEYYTSTEYRPVKEIAEASRTGPATNIISGLAVGMESTALPVLVIVA 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 489 AIISAYWLGNtsglvdengiPTGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESVREITDLLDAVGN 568
Cdd:PRK00733  369 AILGAYLLGM----------AGAGLYGIALAAVGMLSTAGIIVAVDAYGPITDNAGGIAEMAGLPPEVRKITDALDAVGN 438
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 569 TTKATTKGFAIGSAALASFLLFSAYMDEV-SAFANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAWACAAVGRTAQEVVNE 647
Cdd:PRK00733  439 TTKAVTKGFAIGSAALAALALFAAYIDELaGLLGGGGILSLDLSNPYVLVGLLIGGMLPFLFSALAMTAVGRAAGAMVEE 518
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 648 VRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLvfrilgyytgqpLLGAKVVASMLMFATVC 727
Cdd:PRK00733  519 VRRQFREIPGIMEGTAKPDYARCVDISTKAALKEMILPGLLAVLAPIAVGF------------LLGPEALGGLLAGAIVT 586
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063696966 728 GILMALFLNTAGGAWDNAKKYIETGALGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKMLATITLVMAPVF 801
Cdd:PRK00733  587 GLLLAIFMANAGGAWDNAKKYIEDGNHGGKGSEAHKAAVVGDTVGDPFKDTAGPALNPLIKLMNIVALLIAPLL 660
V_PPase TIGR01104
vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases ...
69-801 0e+00

vacuolar-type H(+)-translocating pyrophosphatase; This model describes proton pyrophosphatases from eukaryotes (predominantly plants), archaea and bacteria. It is an integral membrane protein and is suggested to have about 15 membrane spanning domains. Proton translocating inorganic pyrophosphatase, like H(+)-ATPase, acidifies the vacuoles and is pivotal to the vacuolar secondary active transport systems in plants. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273444  Cd Length: 695  Bit Score: 596.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966  69 VFVFTVCIISFLLSIYLTKWVLAKDEGPPEMVEISDAIRDGAEGFFRTQYSTIskmAILLAFVILCIYLFrsltpqqeaA 148
Cdd:TIGR01104   3 ILIPVCAVIGIAYAVLQWVWVSRVKLGTAKMAEIQQAISEGATAFLFTEYKYV---AVFMVAFAVLIFVF---------L 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 149 GLGRAMSAYITVAaFLLGALCSGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAGGFSALVVVGMAVIGIAILYST 228
Cdd:TIGR01104  71 GSREGFSDFSTVA-FLLGAVTSLLAGYLGMKIATYANARTTLEARKGVGKALIVAFRSGAVMGFLLAGLGLLVLYITILV 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 229 FYVWLGVGSPGSMNVtdlpllLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNV 308
Cdd:TIGR01104 150 FKIYYGDDWEGLFEP------ITGYGFGASSMALFGRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNV 223
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 309 GDCAARGADLFESIAAEIISAMILGGTMAkkckIEDPSGFI--LFPLVVHSfdliisSIGILSIKGTRDASVKsPVEDPM 386
Cdd:TIGR01104 224 GDIAGMGADLFESYAESSCAALVLASISS----FGLPHDFTamLYPLALSS------VGILVCLLTTLFVKIK-PVKEIE 292
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 387 AVLQKGYSLTIILAVITFGASTRWLLYT--------EQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLAL 458
Cdd:TIGR01104 293 PALKKQLIISTVLMTVGVAVISWVALPTgftifnfgTQKEVSNWQLFLCVAVGLWAGLLIGFVTEYYTSNAYSPVQDVAD 372
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 459 ASSTGHGTNIIAGVSLGLESTALPVLTISVAIISAYWLgntsglvdengiptGGLFGTAVATMGMLSTAAYVLTMDMFGP 538
Cdd:TIGR01104 373 SCRTGAATNVIFGLALGYKSVIIPIFAIAASIIVSFSF--------------AGMYGIAMAALGMLSTAGTGLAIDAYGP 438
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 539 IADNAGGIVEMSQQPESVREITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMDEvsafanVSFKEVDIAIPEVFVG 618
Cdd:TIGR01104 439 ISDNAGGIAEMAGLPHRVRERTDALDAVGNTTAAIGKGFAIGSAALVALALFGAFVSR------AVITTVDVLTPKVFIG 512
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 619 GLLGAMLIFLFSAWACAAVGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGL 698
Cdd:TIGR01104 513 LFVGAMLPYWFSSMTMKSVGRAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGLLVMLTPLIVGF 592
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 699 VFrilgyytgqpllGAKVVASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGA-----LGGKGSEAHKAAVTGDTVGD 773
Cdd:TIGR01104 593 LF------------GVETLSGVLAGVLVSGVQIAISASNTGGAWDNAKKYIEAGSeharsLGPKGSEAHKAAVIGDTVGD 660
                         730       740
                  ....*....|....*....|....*...
gi 1063696966 774 PFKDTAGPSIHVLIKMLATITLVMAPVF 801
Cdd:TIGR01104 661 PLKDTSGPSLNILIKLMAVESLVFAPFF 688
PLN02255 PLN02255
H(+) -translocating inorganic pyrophosphatase
101-801 2.86e-150

H(+) -translocating inorganic pyrophosphatase


Pssm-ID: 215143  Cd Length: 765  Bit Score: 458.53  E-value: 2.86e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 101 EISDAIRDGAEGFFRTQYSTISKMAILLAFVIlciYLFR------SLTPQQEAAGLGRA-----MSAYITVAAFLLGALC 169
Cdd:PLN02255   75 EIQNAISEGATSFLFTEYKYVGIFMVIFAAVI---FVFLgsvegfSTKSQPCTYDKGKLckpalANAAFSTVAFLLGALT 151
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 170 SGIAGYVGMWVSVRANVRVSSAARRSAREALQIAVRAG---GFsALVVVGMAVIGIAI-LYSTFYV--WLGvgspgsmnv 243
Cdd:PLN02255  152 SVVSGFLGMKIATYANARTTLEARKGVGKAFITAFRSGavmGF-LLAANGLLVLYIAInLFKLYYGddWEG--------- 221
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 244 tdLPLLLVGYGFGASFVALFAQLGGGIYTKGADVGADLVGKVEQGIPEDDPRNPAVIADLVGDNVGDCAARGADLFESIA 323
Cdd:PLN02255  222 --LYEAITGYGLGGSSMALFGRVGGGIYTKAADVGADLVGKVERNIPEDDPRNPAVIADNVGDNVGDIAGMGSDLFGSYA 299
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 324 AEIISAMILGGTMAkkCKIEDPSGFILFPLVVHSFDLIISSIGILSikGTRDASVKSPVE-DPMAVLQKGYS---LTIIL 399
Cdd:PLN02255  300 ESSCAALVVASISS--FGINHDFTAMCYPLLISSVGIIVCLITTLF--ATDFFEIKAVKEiEPALKKQLIIStvlMTVGI 375
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 400 AVITFGA---STRWLLYTEQAPSAWFNFALCGLVGIITAYIFVWISKYYTDYKHEPVRTLALASSTGHGTNIIAGVSLGL 476
Cdd:PLN02255  376 AVVSWLAlpsSFTIFNFGTQKVVKNWQLFFCVAIGLWAGLIIGFVTEYYTSNAYSPVQDVADSCRTGAATNVIFGLALGY 455
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 477 ESTALPVLTISVAIISAYWLgntsglvdengiptGGLFGTAVATMGMLSTAAYVLTMDMFGPIADNAGGIVEMSQQPESV 556
Cdd:PLN02255  456 KSVIIPIFAIAVSIYVSFSL--------------AAMYGIAVAALGMLSTIATGLAIDAYGPISDNAGGIAEMAGMSHRI 521
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 557 REITDLLDAVGNTTKATTKGFAIGSAALASFLLFSAYMdevsafANVSFKEVDIAIPEVFVGGLLGAMLIFLFSAWACAA 636
Cdd:PLN02255  522 RERTDALDAAGNTTAAIGKGFAIGSAALVSLALFGAFV------SRAGISTVDVLTPKVFIGLIVGAMLPYWFSAMTMKS 595
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 637 VGRTAQEVVNEVRRQFIERPGIMEYKEKPDYSRCVAIVASAALREMIKPGALAIASPIVVGLVFrilgyytgqpllGAKV 716
Cdd:PLN02255  596 VGSAALKMVEEVRRQFNTIPGLMEGTAKPDYATCVKISTDASIKEMIPPGALVMLTPLIVGTLF------------GVET 663
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063696966 717 VASMLMFATVCGILMALFLNTAGGAWDNAKKYIETGA------LGGKGSEAHKAAVTGDTVGDPFKDTAGPSIHVLIKML 790
Cdd:PLN02255  664 LSGVLAGALVSGVQIAISASNTGGAWDNAKKYIEAGAseharsLGPKGSDPHKAAVIGDTIGDPLKDTSGPSLNILIKLM 743
                         730
                  ....*....|.
gi 1063696966 791 ATITLVMAPVF 801
Cdd:PLN02255  744 AVESLVFAPFF 754
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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