NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1063705628|ref|NP_001324867|]
View 

Tryptophan/tyrosine permease [Arabidopsis thaliana]

Protein Classification

SLC5/6 family protein; NCS1 family transporter( domain architecture ID 10505197)

SLC5/6 (solute carrier 5/6) family protein may function as a transporter| NCS1 (nucleobase-cation-symport-1) family transporter is an essential component of salvage pathways for nucleobases and related metabolites such as allantoin, uracil, thiamine, and nicotinamide riboside

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Trp_Tyr_perm pfam03222
Tryptophan/tyrosine permease family;
116-540 2.96e-127

Tryptophan/tyrosine permease family;


:

Pssm-ID: 367404  Cd Length: 393  Bit Score: 377.40  E-value: 2.96e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 116 KGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFAAMEEdnaaeVSFTGLATKSF 195
Cdd:pfam03222   1 KTPSLLGGVLIIAGTAIGAGMLALPVATAGAGFIPSLLLLILSWFLMLASGLLLLEVYLWYPEG-----ASFNTLAKDLL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 196 GNKFGVFVAFVYASLSFSLMVACVSGIGSIVSQWFPSMN-----PFLANAIFPLVSGILIGFFPFnAIDFTNRGLCFLML 270
Cdd:pfam03222  76 GKKGNIIAGLVYAFLLYILTYAYISGGGSILSRVIPEMFgipwsARAAPLIFTLLFGPFVWAGTK-AVDRINRVLIFGKI 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 271 FSITSLVAIGLSVARSNVLASFGQsCWKVSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAMVLS 350
Cdd:pfam03222 155 IAFALVFSGLLPKIKGDLLLDALD-TSYWPYILMALPVFFTSFGFHGNVPSLYKYYGGNVKKVRKAILIGTAIPLVLYIL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 351 WNLIVLG------LARITVPAAPSSTIDPISLLLSVNPSALSAVQGFAFSALATSLIGYAVSFPKQLLDTWKLvSKQSNG 424
Cdd:pfam03222 234 WQLATLGnlpreeFAPIIAKGGNLDTLVEALLGVLKSPSFELALELFSFFALATSFLGVALGLFDYLADLFKF-DDSKNG 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 425 NGRLGSVSFSSkerdrrtngrasyneparardgfeavvmlfvlgvPALIATFFPSTFSRALDFAGvYANCFLFGVLPPAM 504
Cdd:pfam03222 313 RFKTGLLTFLP----------------------------------PLVWALFFPEGFLYALGYAG-LAATIWAVILPALL 357

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1063705628 505 AYIQQSRKKLRPWVLPGGNFTLLILFAIAIILGIWH 540
Cdd:pfam03222 358 AWKARKRFPNAPYRVWGGNKTLLLVILFGIVVILVH 393
 
Name Accession Description Interval E-value
Trp_Tyr_perm pfam03222
Tryptophan/tyrosine permease family;
116-540 2.96e-127

Tryptophan/tyrosine permease family;


Pssm-ID: 367404  Cd Length: 393  Bit Score: 377.40  E-value: 2.96e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 116 KGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFAAMEEdnaaeVSFTGLATKSF 195
Cdd:pfam03222   1 KTPSLLGGVLIIAGTAIGAGMLALPVATAGAGFIPSLLLLILSWFLMLASGLLLLEVYLWYPEG-----ASFNTLAKDLL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 196 GNKFGVFVAFVYASLSFSLMVACVSGIGSIVSQWFPSMN-----PFLANAIFPLVSGILIGFFPFnAIDFTNRGLCFLML 270
Cdd:pfam03222  76 GKKGNIIAGLVYAFLLYILTYAYISGGGSILSRVIPEMFgipwsARAAPLIFTLLFGPFVWAGTK-AVDRINRVLIFGKI 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 271 FSITSLVAIGLSVARSNVLASFGQsCWKVSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAMVLS 350
Cdd:pfam03222 155 IAFALVFSGLLPKIKGDLLLDALD-TSYWPYILMALPVFFTSFGFHGNVPSLYKYYGGNVKKVRKAILIGTAIPLVLYIL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 351 WNLIVLG------LARITVPAAPSSTIDPISLLLSVNPSALSAVQGFAFSALATSLIGYAVSFPKQLLDTWKLvSKQSNG 424
Cdd:pfam03222 234 WQLATLGnlpreeFAPIIAKGGNLDTLVEALLGVLKSPSFELALELFSFFALATSFLGVALGLFDYLADLFKF-DDSKNG 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 425 NGRLGSVSFSSkerdrrtngrasyneparardgfeavvmlfvlgvPALIATFFPSTFSRALDFAGvYANCFLFGVLPPAM 504
Cdd:pfam03222 313 RFKTGLLTFLP----------------------------------PLVWALFFPEGFLYALGYAG-LAATIWAVILPALL 357

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1063705628 505 AYIQQSRKKLRPWVLPGGNFTLLILFAIAIILGIWH 540
Cdd:pfam03222 358 AWKARKRFPNAPYRVWGGNKTLLLVILFGIVVILVH 393
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
114-536 2.82e-38

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 144.90  E-value: 2.82e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 114 TKKGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFAAmeednAAEVSFTGLATK 193
Cdd:COG0814     6 MKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSS-----PPGADITTVVEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 194 SFGNKFGVFVAFVYASLSFSLMVACVSGIGSIVS-----QWFPSMNPFLANAIFPLVSGILIgFFPFNAIDFTNRGLCFL 268
Cdd:COG0814    81 YLGKGGGILIGLLYFFLLYPLLLAYISGGGNILAsflvnQLGLTIPRWLLSLIFILVLGAIV-WLGTRLVDRVNRILVFP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 269 MLFSITSLVAIGL-SVARSNVLASFGQSCWKVsmVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAM 347
Cdd:COG0814   160 KIIAFLLLSLYLIpHWNLANLLNSALPSYLKY--LWLALPVLLTSFGFHPIIPSLVKYYRKDAKKLRRAILIGSLIPLVI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 348 VLSWNLIVLG-LARITVPAAPSSTIDPISLLLSVNPSAL--SAVQGFAFSALATSLIGYAVSfpkqLLDTWK-LVSKQSN 423
Cdd:COG0814   238 YLFWVFSCLGsLPPEEFAEAKAQNISLLSALANVFNSPLisYLGPLFAFFAIATSFLGVYLG----LFDFLAdLFKKKKS 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 424 GNGRLGSvsfsskerdrrtngrasyneparardgfeavvMLFVLGVPALIATFFPSTFSRALDFAGVYAnCFLFGVLPPA 503
Cdd:COG0814   314 KKGRLKT--------------------------------ALLTFLPPWIVALLNPSIFILALGYAGPII-AILLFILPAL 360

                         410       420       430
                  ....*....|....*....|....*....|...
gi 1063705628 504 MAYIQQSRKKLrPWVLPGGNFTLLILFAIAIIL 536
Cdd:COG0814   361 LVWKVRARFPL-KYRVPGGKLSLIFVILFGLLA 392
PRK15132 PRK15132
tyrosine transporter TyrP; Provisional
 123-538 4.69e-17

tyrosine transporter TyrP; Provisional


Pssm-ID: 185086  Cd Length: 403  Bit Score: 83.20  E-value: 4.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 123 AVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSfaameEDNAAEVSFTGLATKSFGNKFGVF 202
Cdd:PRK15132    8 SIFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLWALMCYTALLLLEVY-----QHVPADTGLGTLAKRYLGRYGQWL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 203 VAFVYASLSFSLMVACVSGIG----SIVSQWF-PSMNPFLANAIFPLVSG--ILIGFfpfNAIDFTNRGL-CFLMLFSIT 274
Cdd:PRK15132   83 TGFSMMFLMYALTAAYISGAGellaSSISDWTgISMSPTAGVLLFTLVAGgvVCVGT---SSVDLFNRFLfSAKIIFLVV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 275 SLVAIGLSVARSNVLASFGQScwkvSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAMVLSWNLI 354
Cdd:PRK15132  160 MLALMMPHIHKVNLLTLPLQQ----GLALSAIPVIFTSFGFHGSVPSIVSYMGGNIRKLRWVFIIGSAIPLVAYIFWQLA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 355 VLGlaritvpAAPSSTIDPI--------SLLLSV-----NPSALSAVQGFAFSALATSLIGYAVSFPKQLLDTWKlvskq 421
Cdd:PRK15132  236 TLG-------SIDSTTFMGLlanhaglnGLLQALrevvaSPHVELAVHLFADLALATSFLGVALGLFDYLADLFQ----- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 422 sngngrlgsvsfsskeRDRRTNGRasyneparardgFEAVVMLFVlgVPALIATFFPSTFSRALDFAGVyANCFLFGVLP 501
Cdd:PRK15132  304 ----------------RRNTVGGR------------LQTGLITFL--PPLAFALFYPRGFVMALGYAGV-ALAVLALLLP 352

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 1063705628 502 PAMAYIQQSRKKLRPWVLPGGNFTLLILFA-----IAIILGI 538
Cdd:PRK15132  353 SLLVWQSRKQNPQAGYRVKGGRPALALVFLcgiavIGIQFLI 394
 
Name Accession Description Interval E-value
Trp_Tyr_perm pfam03222
Tryptophan/tyrosine permease family;
116-540 2.96e-127

Tryptophan/tyrosine permease family;


Pssm-ID: 367404  Cd Length: 393  Bit Score: 377.40  E-value: 2.96e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 116 KGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFAAMEEdnaaeVSFTGLATKSF 195
Cdd:pfam03222   1 KTPSLLGGVLIIAGTAIGAGMLALPVATAGAGFIPSLLLLILSWFLMLASGLLLLEVYLWYPEG-----ASFNTLAKDLL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 196 GNKFGVFVAFVYASLSFSLMVACVSGIGSIVSQWFPSMN-----PFLANAIFPLVSGILIGFFPFnAIDFTNRGLCFLML 270
Cdd:pfam03222  76 GKKGNIIAGLVYAFLLYILTYAYISGGGSILSRVIPEMFgipwsARAAPLIFTLLFGPFVWAGTK-AVDRINRVLIFGKI 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 271 FSITSLVAIGLSVARSNVLASFGQsCWKVSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAMVLS 350
Cdd:pfam03222 155 IAFALVFSGLLPKIKGDLLLDALD-TSYWPYILMALPVFFTSFGFHGNVPSLYKYYGGNVKKVRKAILIGTAIPLVLYIL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 351 WNLIVLG------LARITVPAAPSSTIDPISLLLSVNPSALSAVQGFAFSALATSLIGYAVSFPKQLLDTWKLvSKQSNG 424
Cdd:pfam03222 234 WQLATLGnlpreeFAPIIAKGGNLDTLVEALLGVLKSPSFELALELFSFFALATSFLGVALGLFDYLADLFKF-DDSKNG 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 425 NGRLGSVSFSSkerdrrtngrasyneparardgfeavvmlfvlgvPALIATFFPSTFSRALDFAGvYANCFLFGVLPPAM 504
Cdd:pfam03222 313 RFKTGLLTFLP----------------------------------PLVWALFFPEGFLYALGYAG-LAATIWAVILPALL 357

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 1063705628 505 AYIQQSRKKLRPWVLPGGNFTLLILFAIAIILGIWH 540
Cdd:pfam03222 358 AWKARKRFPNAPYRVWGGNKTLLLVILFGIVVILVH 393
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
114-536 2.82e-38

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 144.90  E-value: 2.82e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 114 TKKGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFAAmeednAAEVSFTGLATK 193
Cdd:COG0814     6 MKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSS-----PPGADITTVVEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 194 SFGNKFGVFVAFVYASLSFSLMVACVSGIGSIVS-----QWFPSMNPFLANAIFPLVSGILIgFFPFNAIDFTNRGLCFL 268
Cdd:COG0814    81 YLGKGGGILIGLLYFFLLYPLLLAYISGGGNILAsflvnQLGLTIPRWLLSLIFILVLGAIV-WLGTRLVDRVNRILVFP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 269 MLFSITSLVAIGL-SVARSNVLASFGQSCWKVsmVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAM 347
Cdd:COG0814   160 KIIAFLLLSLYLIpHWNLANLLNSALPSYLKY--LWLALPVLLTSFGFHPIIPSLVKYYRKDAKKLRRAILIGSLIPLVI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 348 VLSWNLIVLG-LARITVPAAPSSTIDPISLLLSVNPSAL--SAVQGFAFSALATSLIGYAVSfpkqLLDTWK-LVSKQSN 423
Cdd:COG0814   238 YLFWVFSCLGsLPPEEFAEAKAQNISLLSALANVFNSPLisYLGPLFAFFAIATSFLGVYLG----LFDFLAdLFKKKKS 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 424 GNGRLGSvsfsskerdrrtngrasyneparardgfeavvMLFVLGVPALIATFFPSTFSRALDFAGVYAnCFLFGVLPPA 503
Cdd:COG0814   314 KKGRLKT--------------------------------ALLTFLPPWIVALLNPSIFILALGYAGPII-AILLFILPAL 360

                         410       420       430
                  ....*....|....*....|....*....|...
gi 1063705628 504 MAYIQQSRKKLrPWVLPGGNFTLLILFAIAIIL 536
Cdd:COG0814   361 LVWKVRARFPL-KYRVPGGKLSLIFVILFGLLA 392
PRK15132 PRK15132
tyrosine transporter TyrP; Provisional
 123-538 4.69e-17

tyrosine transporter TyrP; Provisional


Pssm-ID: 185086  Cd Length: 403  Bit Score: 83.20  E-value: 4.69e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 123 AVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSfaameEDNAAEVSFTGLATKSFGNKFGVF 202
Cdd:PRK15132    8 SIFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLWALMCYTALLLLEVY-----QHVPADTGLGTLAKRYLGRYGQWL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 203 VAFVYASLSFSLMVACVSGIG----SIVSQWF-PSMNPFLANAIFPLVSG--ILIGFfpfNAIDFTNRGL-CFLMLFSIT 274
Cdd:PRK15132   83 TGFSMMFLMYALTAAYISGAGellaSSISDWTgISMSPTAGVLLFTLVAGgvVCVGT---SSVDLFNRFLfSAKIIFLVV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 275 SLVAIGLSVARSNVLASFGQScwkvSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVVPLAMVLSWNLI 354
Cdd:PRK15132  160 MLALMMPHIHKVNLLTLPLQQ----GLALSAIPVIFTSFGFHGSVPSIVSYMGGNIRKLRWVFIIGSAIPLVAYIFWQLA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 355 VLGlaritvpAAPSSTIDPI--------SLLLSV-----NPSALSAVQGFAFSALATSLIGYAVSFPKQLLDTWKlvskq 421
Cdd:PRK15132  236 TLG-------SIDSTTFMGLlanhaglnGLLQALrevvaSPHVELAVHLFADLALATSFLGVALGLFDYLADLFQ----- 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 422 sngngrlgsvsfsskeRDRRTNGRasyneparardgFEAVVMLFVlgVPALIATFFPSTFSRALDFAGVyANCFLFGVLP 501
Cdd:PRK15132  304 ----------------RRNTVGGR------------LQTGLITFL--PPLAFALFYPRGFVMALGYAGV-ALAVLALLLP 352

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 1063705628 502 PAMAYIQQSRKKLRPWVLPGGNFTLLILFA-----IAIILGI 538
Cdd:PRK15132  353 SLLVWQSRKQNPQAGYRVKGGRPALALVFLcgiavIGIQFLI 394
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
111-539 1.46e-08

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 57.21  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 111 THETKKGKSFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELsfAAMEEDNAAEVSFtgl 190
Cdd:COG0531     6 SSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAEL--ASAFPRAGGAYTY--- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 191 ATKSFGNKFGVFVAFVYASLSFSLMVACVSGIGSIVSQWFPsmnpflANAIFPLVSGILIGFFPFNAID-----FTNRGL 265
Cdd:COG0531    81 ARRALGPLLGFLAGWALLLSYVLAVAAVAVAFGGYLSSLFP------AGGSVLIALVLILLLTLLNLRGvkesaKVNNIL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 266 CFLMLFSITSLVAIGLSVARSNVLASFGQSCWKVSMVLPAVPVMVLT-LGFHVITpficNLAG---DSVSDARRAILVGG 341
Cdd:COG0531   155 TVLKLLVLLLFIVVGLFAFDPANFTPFLPAGGGLSGVLAALALAFFAfTGFEAIA----NLAEeakNPKRNIPRAIILSL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 342 VVPLAMVLSWNLIVLGLARITVPAAPSstiDPISLLLS--VNPSALSAVQGFAFSALATSLIGYAVSFPKQLLdtwklvs 419
Cdd:COG0531   231 LIVGVLYILVSLALTGVVPYDELAASG---APLADAAEavFGPWGAILIALGALLSLLGALNASILGASRLLY------- 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 420 kqSNGNGRLGSVSFSskerdrRTNGRasYNEPARArdgfeavvMLFVLGVPALIATFFPSTFSRALDFAGVyanCFLFGV 499
Cdd:COG0531   301 --AMARDGLLPKVFA------KVHPR--FGTPVNA--------ILLTGVIALLLLLLGAASFTALASLASV---GVLLAY 359

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 500 LPPAMAYIQQSRKKL---RPWVLPG-----------------GNFTLLILFAIAIILGIW 539
Cdd:COG0531   360 LLVALAVIVLRRRRPdlpRPFRVPLplipilgillclfllylLGPGALLIGLVLLAIGLL 419
PRK09664 PRK09664
low affinity tryptophan permease TnaB;
115-536 2.08e-05

low affinity tryptophan permease TnaB;


Pssm-ID: 182022  Cd Length: 415  Bit Score: 46.81  E-value: 2.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 115 KKGKSFWAaVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSFaameeDNAAEVSFTGLATKS 194
Cdd:PRK09664    7 KKHSAFWG-VMVIAGTVIGGGMFALPVDLAGAWFFWGAFILIIAWFSMLHSGLLLLEANL-----NYPVGSSFNTITKDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 195 FGNKFGVFVAFVYASLSFSLMVACVSGIGSIVSQWFpSMNpfLANAIFPLVSGILIGFFPFNAIDFTNRGLC-----FLM 269
Cdd:PRK09664   81 IGNTWNIISGITVAFVLYILTYAYISANGAIISETI-SMN--LGYHANPRIVGICTAIFVASVLWISSLAASritslFLG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 270 LFSITSLVAIGLSVAR------SNVLASFGQSCWkVSMVLPAVPVMVLTLGFHVITPFICNLAGDSVSDARRAILVGGVV 343
Cdd:PRK09664  158 LKIISFVIVFGSFFFQvdysilRDATSTTAGTSY-FPYIFMALPVCLASFGFHGNIPSLIICYGKRKDKLIKSVVFGSLL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 344 PLAMVLSWNLIVLG-LARITVPAAPSSTIDPISLLLSVNPSALSAVQGF---AFS--ALATSLIGYAVSFPKQLLDTWKL 417
Cdd:PRK09664  237 ALVIYLFWLYCTMGnIPRESFKAIISSGGNVDSLVKSFLGTKQHGIIEFcllVFSnlAVASSFFGVTLGLFDYLADLFKI 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 418 vskqsngngrlgsvsfsskerDRRTNGRasyneparardgFEAVVMLFVlgVPALIATFFPSTFSRALDFAGVYANcfLF 497
Cdd:PRK09664  317 ---------------------DNSHGGR------------FKTVLLTFL--PPALLYLIFPNGFIYGIGGAGLCAT--IW 359

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1063705628 498 GVLPPAMAYIqQSRKKL--RPWVLPGGNF--TLLILFAIAIIL 536
Cdd:PRK09664  360 AVIIPAVLAI-KARKKFpnQMFTVWGGNLipAIVILFGITVIL 401
Aa_trans pfam01490
Transmembrane amino acid transporter protein; This transmembrane region is found in many amino ...
 119-540 8.56e-05

Transmembrane amino acid transporter protein; This transmembrane region is found in many amino acid transporters including UNC-47 and MTR. UNC-47 encodes a vesicular amino butyric acid (GABA) transporter, (VGAT). UNC-47 is predicted to have 10 transmembrane domains. MTR is a N system amino acid transporter system protein involved in methyltryptophan resistance. Other members of this family include proline transporters and amino acid permeases.


Pssm-ID: 279788  Cd Length: 410  Bit Score: 44.99  E-value: 8.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 119 SFWAAVSLIIGTAVGPGMLGLPAATIRSGSIPSTIALLCSWVYVISSILLVAELSfAAMEEDNAAEVSFTGLATKSFGNK 198
Cdd:pfam01490   4 SAWQAVFNLINAIIGAGVLSLPYAFKQLGWIPGLILLLIVGLISLYTAHLLVRCS-KEVPVTGKRNKSYGDLGYRLLGPK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 199 FGVFVAFVYASLSF----SLMVACVSGIGSIVSQWFPsmNPFLANAIFPLVSGILigFFPFNAI-DFTN-RGLCFLMLFS 272
Cdd:pfam01490  83 GRLLILFAILLNLFgvciSYLIFAGDNLPAIFDSFFD--TCPISLVYFIIIFGLI--FIPLSFIpNLSAlSILSLLAAVS 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 273 ITSLVAIGLSVARSNVL----------ASFGQSCWKVSMvlpAVPVMVLTLGFHVITPFICNlagdSVSDarrailvggv 342
Cdd:pfam01490 159 SLYYIVILVLSVAEGIVltaqgvghlgSKTNIKLAGTFL---AIGIIVFAFEGHAVLLPIQN----EMKN---------- 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 343 vPLAMVLSWNLIVLGLARITVPAAP----------SSTIDPISLLLSVNPSALSAVQGFafsaLATSLIGyavSFPKQLL 412
Cdd:pfam01490 222 -PSKFKAMTKILLTAIIIATVLYILiglvgylafgDNVKGNILLNLPKSAWLIDIANLL----LVLHVIL---SFPLQLF 293

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063705628 413 DTWKLVSKQSNgngrlgsvsfsskerdRRTNGRASYNEPARARDGFEAVVMLFVLGVPALIATFFPStFSRALDFAGVYA 492
Cdd:pfam01490 294 PIRQIVENLLF----------------RKEAPFGASGKNNPKSKLLRVVIRSGLVVITYLIAISVPF-FGDLLSLVGATS 356

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063705628 493 nCFLFGVLPPAMAYIQQSRKKLRP----WVLPGGNFTLLILFAIAIILGIWH 540
Cdd:pfam01490 357 -CAPLSFILPPLFHLKLKKTKKKSqeklWKPDILDVICIVIGLLLMAYGVAG 407
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH