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Conserved domains on  [gi|1063718341|ref|NP_001327881|]
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disulfide isomerase-like protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ER_PDI_fam super family cl36828
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 23-74 4.41e-14

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


The actual alignment was detected with superfamily member TIGR01130:

Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 66.62  E-value: 4.41e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063718341  23 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 74
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
PLN02692 super family cl29047
alpha-galactosidase
 3-27 5.24e-04

alpha-galactosidase


The actual alignment was detected with superfamily member PLN02692:

Pssm-ID: 178295 [Multi-domain]  Cd Length: 412  Bit Score: 37.71  E-value: 5.24e-04
                          10        20
                  ....*....|....*....|....*
gi 1063718341   3 RTITMVIKMSILMILISSMVMNMVE 27
Cdd:PLN02692    2 ERRAMVIKMALLLILISVMVMVMVE 26
 
Name Accession Description Interval E-value
ER_PDI_fam TIGR01130
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 23-74 4.41e-14

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 66.62  E-value: 4.41e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063718341  23 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 74
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
PTZ00102 PTZ00102
disulphide isomerase; Provisional
 30-79 9.02e-06

disulphide isomerase; Provisional


Pssm-ID: 240266 [Multi-domain]  Cd Length: 477  Bit Score: 42.82  E-value: 9.02e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063718341  30 VDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIVQVSER 79
Cdd:PTZ00102  327 VEALIEFFKDVEAGKVEKSIKSEPIPEEQDGPVKVVVGNTFEEIVFKSDK 376
PLN02692 PLN02692
alpha-galactosidase
 3-27 5.24e-04

alpha-galactosidase


Pssm-ID: 178295 [Multi-domain]  Cd Length: 412  Bit Score: 37.71  E-value: 5.24e-04
                          10        20
                  ....*....|....*....|....*
gi 1063718341   3 RTITMVIKMSILMILISSMVMNMVE 27
Cdd:PLN02692    2 ERRAMVIKMALLLILISVMVMVMVE 26
 
Name Accession Description Interval E-value
ER_PDI_fam TIGR01130
protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide ...
 23-74 4.41e-14

protein disulfide isomerase, eukaryotic; This model represents eukaryotic protein disulfide isomerases retained in the endoplasmic reticulum (ER) and closely related forms. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase and dolichyl-diphosphooligosaccharide-protein glycotransferase. Members of this family have at least two protein-disulfide domains, each similar to thioredoxin but with the redox-active disulfide in the motif PWCGHCK, and an ER retention signal at the extreme C-terminus (KDEL, HDEL, and similar motifs).


Pssm-ID: 273457 [Multi-domain]  Cd Length: 462  Bit Score: 66.62  E-value: 4.41e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063718341  23 MNMVEVEVDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIV 74
Cdd:TIGR01130 309 MDQEEFSSENLEAFVKDFLDGKLKPYLKSEPIPEDDEGPVKVLVGKNFDEIV 360
PTZ00102 PTZ00102
disulphide isomerase; Provisional
 30-79 9.02e-06

disulphide isomerase; Provisional


Pssm-ID: 240266 [Multi-domain]  Cd Length: 477  Bit Score: 42.82  E-value: 9.02e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063718341  30 VDQIESWVKDFQDGKAAVHKNSQPIPAENNEPVKLVVAESLDDIVQVSER 79
Cdd:PTZ00102  327 VEALIEFFKDVEAGKVEKSIKSEPIPEEQDGPVKVVVGNTFEEIVFKSDK 376
PLN02692 PLN02692
alpha-galactosidase
 3-27 5.24e-04

alpha-galactosidase


Pssm-ID: 178295 [Multi-domain]  Cd Length: 412  Bit Score: 37.71  E-value: 5.24e-04
                          10        20
                  ....*....|....*....|....*
gi 1063718341   3 RTITMVIKMSILMILISSMVMNMVE 27
Cdd:PLN02692    2 ERRAMVIKMALLLILISVMVMVMVE 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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