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Conserved domains on  [gi|1063743517|ref|NP_001330538|]
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beta-hydroxyisobutyryl-CoA hydrolase 1 [Arabidopsis thaliana]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
1-378 0e+00

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02988:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 381  Bit Score: 741.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIN 80
Cdd:PLN02988    1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  81 QGNWRLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
Cdd:PLN02988   81 QGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDR 240
Cdd:PLN02988  161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 241 CFSRRTVEEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
Cdd:PLN02988  241 CFSRRTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVERE---DDLKLPPRNNLPALGIAKL 378
Cdd:PLN02988  321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEeewDDLKLPPRNNLPALAIAKL 381
 
Name Accession Description Interval E-value
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-378 0e+00

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 741.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIN 80
Cdd:PLN02988    1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  81 QGNWRLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
Cdd:PLN02988   81 QGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDR 240
Cdd:PLN02988  161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 241 CFSRRTVEEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
Cdd:PLN02988  241 CFSRRTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVERE---DDLKLPPRNNLPALGIAKL 378
Cdd:PLN02988  321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEeewDDLKLPPRNNLPALAIAKL 381
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-353 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 522.03  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDINQGNWRLGANYFSSEYML 97
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  98 NYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDG 177
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 178 AEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDRCFSRRTVEEIISALERE 257
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 258 AtqEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGeisKDFVEGCRAILVDKDKNPKWE 337
Cdd:pfam16113 241 A--DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRR---PDFVEGVRALLIDKDRNPKWS 315
                         330
                  ....*....|....*.
gi 1063743517 338 PRRLEDMKDSMVEQYF 353
Cdd:pfam16113 316 PATLEEVTDEMVDAYF 331
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
11-204 4.65e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 184.69  E-value: 4.65e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWrlGANY 90
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEE--ARAF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVG 169
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPaRARELL 158
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCR 204
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
11-210 3.82e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 158.02  E-value: 3.82e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRlgaNY 90
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEAR---AF 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVG 169
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLaRAKELL 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRL-TALEADLCRINSNDP 210
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDELlAAALALAARLAAGPP 199
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
22-210 2.49e-18

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 83.75  E-value: 2.49e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAavVRDinqgnwRLGANYFSSEYMLNY- 99
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGdKAFCSGGDQK--VRG------DYGYIDDSGVHRLNVl 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 100 ----VMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG-FFGEYVGLTGAR 174
Cdd:TIGR01929  88 dvqrQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGqKKAREIWFLCRQ 167
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063743517 175 LDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDP 210
Cdd:TIGR01929 168 YDAKQALDMGLVNTVVPLADLEKETVRWCReILQKSP 204
 
Name Accession Description Interval E-value
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
1-378 0e+00

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 741.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIN 80
Cdd:PLN02988    1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  81 QGNWRLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
Cdd:PLN02988   81 QGNWRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDR 240
Cdd:PLN02988  161 PGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYTQHPRLKPQSAYHRLDVIDR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 241 CFSRRTVEEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
Cdd:PLN02988  241 CFSRRTVEEIISALEREATQEADGWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFV 320
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVERE---DDLKLPPRNNLPALGIAKL 378
Cdd:PLN02988  321 EGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEeewDDLKLPPRNNLPALAIAKL 381
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-353 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 522.03  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDINQGNWRLGANYFSSEYML 97
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  98 NYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDG 177
Cdd:pfam16113  81 NYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 178 AEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDRCFSRRTVEEIISALERE 257
Cdd:pfam16113 161 ADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFAEESDPPPSPLAAHREAIDRCFSADTVEEIIAALEAE 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 258 AtqEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGeisKDFVEGCRAILVDKDKNPKWE 337
Cdd:pfam16113 241 A--DGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRR---PDFVEGVRALLIDKDRNPKWS 315
                         330
                  ....*....|....*.
gi 1063743517 338 PRRLEDMKDSMVEQYF 353
Cdd:pfam16113 316 PATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
7-354 6.93e-139

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 398.81  E-value: 6.93e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   7 SQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKG-HGRAFCAGGDVAAVVRDINQGNWR 85
Cdd:PRK05617    1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGaGERGFCAGGDIRALYEAARAGDPL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  86 LGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFG 165
Cdd:PRK05617   81 AADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGALG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 166 EYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLcrINSNDPTFAST---ILDAYTQHPrlKQQSAYRRLDVIDRCF 242
Cdd:PRK05617  161 TYLALTGARISAADALYAGLADHFVPSADLPALLDAL--ISLRWDSGADVvdaALAAFATPA--PASELAAQRAWIDECF 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 243 SRRTVEEIISALEReatqEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKgeiSKDFVEG 322
Cdd:PRK05617  237 AGDTVEDIIAALEA----DGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLR---SPDFVEG 309
                         330       340       350
                  ....*....|....*....|....*....|..
gi 1063743517 323 CRAILVDKDKNPKWEPRRLEDMKDSMVEQYFE 354
Cdd:PRK05617  310 VRAVLIDKDRNPKWSPATLEDVTPEDVEAFFA 341
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
5-365 4.07e-138

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 398.40  E-value: 4.07e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQ------VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRD 78
Cdd:PLN02874    1 MAQQVQnpaeevVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKMFYDG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  79 INQGNWRLGANYfsSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
Cdd:PLN02874   81 RESDDSCLEVVY--RMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILS 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 159 RLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVI 238
Cdd:PLN02874  159 RLPGHLGEYLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFSKDVQADEDSILNKQSWI 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 239 DRCFSRRTVEEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKD 318
Cdd:PLN02874  239 NECFSKDTVEEIIKAFESEASKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMNILRSTVSDD 318
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 1063743517 319 FVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEREDDLKLP 365
Cdd:PLN02874  319 VYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVFQPFKAREELQLP 365
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
8-365 2.53e-134

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 389.72  E-value: 2.53e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   8 QSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLG 87
Cdd:PLN02851   41 QDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGADVVSLYHLINEGNVEEC 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  88 ANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEY 167
Cdd:PLN02851  121 KLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGYLGEY 200
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 168 VGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILDAYTQHPRLKQQSAYRRLDVIDRCFSRRTV 247
Cdd:PLN02851  201 LALTGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPAVIEDSLAQYGDLVYPDKSSVLHKIETIDKCFGHDTV 280
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 248 EEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRM-VCHVMKgEISKDFVEGCRAI 326
Cdd:PLN02851  281 EEIIEALENEAASSYDEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAREYRIsLCGVSK-WVSGDFCEGVRAR 359
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 1063743517 327 LVDKDKNPKWEPRRLEDMKDSMVEQYFERV-EREDDLKLP 365
Cdd:PLN02851  360 LVDKDFAPKWDPPSLGEVSKDMVDCYFTPLdESESELELP 399
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
10-365 4.37e-121

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 355.92  E-value: 4.37e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  10 QVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLGAN 89
Cdd:PLN02157   38 QVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPDAIRE 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVG 169
Cdd:PLN02157  118 FFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLG 197
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTILD--AYTQHPrlKQQSAYRRLDVIDRCFSRRTV 247
Cdd:PLN02157  198 LTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESCLEkcAEVAHP--EKTGVIRRIDLLEKCFSHDTV 275
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 248 EEIISALEREATQEADGWISATIQALKKGSPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGEISKDFVEGCRAIL 327
Cdd:PLN02157  276 EEIIDSLEIEAGRRKDTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLIGPMSGNFCEGVRARL 355
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 1063743517 328 VDKDKNPKWEPRRLEDMKDSMVEQYF-ERVEREDDLKLP 365
Cdd:PLN02157  356 IDKDEAPKWDPPSLEKVSEDMVDDYFcALTPTEPDLDLP 394
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
11-204 4.65e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 184.69  E-value: 4.65e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWrlGANY 90
Cdd:cd06558     1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAALSDAGEE--ARAF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVG 169
Cdd:cd06558    79 IRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPaRARELL 158
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCR 204
Cdd:cd06558   159 LTGRRISAEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
11-210 3.82e-46

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 158.02  E-value: 3.82e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRlgaNY 90
Cdd:COG1024     1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAADPEEAR---AF 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVG 169
Cdd:COG1024    78 ARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLaRAKELL 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRL-TALEADLCRINSNDP 210
Cdd:COG1024   158 LTGRRIDAEEALELGLVNRVVPDDELlAAALALAARLAAGPP 199
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
5-201 3.74e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 116.12  E-value: 3.74e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvrdinqGNW 84
Cdd:PRK06688    1 MTMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDF------PKA 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  85 RLGANYFSSEYM--LNYVmATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLpg 162
Cdd:PRK06688   75 PPKPPDELAPVNrfLRAI-AALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRL-- 151
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1063743517 163 ffgeyVG--------LTGARLDGAEMLACGLATHFVPSTRLTAlEAD 201
Cdd:PRK06688  152 -----IGraraaemlLLGEPLSAEEALRIGLVNRVVPAAELDA-EAD 192
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-220 5.57e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 115.53  E-value: 5.57e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  14 EEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDvaavVRDINQGNWRLGANYFSS 93
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGAD----LKEMYGEGPAHQALYREN 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  94 EYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVGLTG 172
Cdd:pfam00378  77 VLDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHsKAMEMLLLG 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063743517 173 ARLDGAEMLACGLATHFVPSTRL--TALEAdLCRINSNDPTFASTILDAY 220
Cdd:pfam00378 157 RRISAQEALKWGLVDKVVPEDQLldEAREL-AEKLAEKSPAALAQLKKAL 205
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
11-222 3.77e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 111.00  E-value: 3.77e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDINQGNWRLGAN 89
Cdd:PRK05980    5 VLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGdRAFSAGADIHEFSASVAAGADVALRD 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYV 168
Cdd:PRK05980   85 FVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRkRALEL 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063743517 169 GLTGARLDGAEMLACGLATHFVPSTRLTALEADLC-RINSNDPTFASTILDAYTQ 222
Cdd:PRK05980  165 LLTGDAFSAERALEIGLVNAVVPHEELLPAARALArRIIRHSPVAVAAILTAVTR 219
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
11-222 1.95e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 106.21  E-value: 1.95e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDinqgnwrlGANY 90
Cdd:PRK06190    6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGD--------GSAY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMAT--YSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASyflSRLPGFFGEY- 167
Cdd:PRK06190   78 GAQDALPNPSPAWpaMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLS---VRLPQKVGIGr 154
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 168 ---VGLTGARLDGAEMLACGLATHFVPSTRL--TALE-ADlcRINSNDPTFASTILDAYTQ 222
Cdd:PRK06190  155 arrMSLTGDFLDAADALRAGLVTEVVPHDELlpRARRlAA--SIAGNNPAAVRALKASYDD 213
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
11-162 5.24e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.16  E-value: 5.24e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINqgnwrlgANY 90
Cdd:PRK06072    2 IKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEFAPDFA-------IDL 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG 162
Cdd:PRK06072   75 RETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG 146
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
5-249 2.49e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 100.55  E-value: 2.49e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGdvaavvrDINQ-G 82
Cdd:PRK06127    7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGeKAFVSGA-------DISQfE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  83 NWRLGAN----YFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
Cdd:PRK06127   80 ESRSDAEavaaYEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 159 RL--PGFFGEYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDPTfasTILDAYTQHPRLKQQSAYRRL 235
Cdd:PRK06127  160 DLvgPSAAKDLF-YTARRFDAAEALRIGLVHRVTAADDLETALADYAAtIAGNAPL---TLRAAKRAIAELLKDEPERDM 235
                         250
                  ....*....|....*...
gi 1063743517 236 DVIDR----CFSRRTVEE 249
Cdd:PRK06127  236 AACQAlvaaCFDSEDYRE 253
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
17-210 7.37e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 96.34  E-value: 7.37e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRdINQGNWRlganyfSSEY 95
Cdd:PRK07657   12 PHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADLKERAG-MNEEQVR------HAVS 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  96 MLNYVMATYSK-AQVSI--LNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL--PGFFGEYVgL 170
Cdd:PRK07657   85 LIRTTMEMVEQlPQPVIaaINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELI-Y 163
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063743517 171 TGARLDGAEMLACGLATHFVPSTRLTALEADLC-RINSNDP 210
Cdd:PRK07657  164 TGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAeKIASNGP 204
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
11-211 8.78e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 93.45  E-value: 8.78e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVaavvrdinqgNW-RLGAN 89
Cdd:PRK05995    6 LEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADL----------NWmKKMAG 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSE---------YMLNyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL 160
Cdd:PRK05995   76 YSDDEnradarrlaDMLR-AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAM 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063743517 161 P-GFFGEYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADLC-RINSNDPT 211
Cdd:PRK05995  155 GeRAARRYF-LTAERFDAAEALRLGLVHEVVPAEALDAKVDELLaALVANSPQ 206
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
1-200 2.75e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 92.03  E-value: 2.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMasqsqVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVvrdin 80
Cdd:PRK05862    1 MAYET-----ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEM----- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  81 qGNWRLgANYFSSEYMLNY-VMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASyflSR 159
Cdd:PRK05862   71 -ADLSF-MDVYKGDYITNWeKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGS---QR 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1063743517 160 LPGFFGEY----VGLTGARLDGAEMLACGLATHFVPSTRL--TALEA 200
Cdd:PRK05862  146 LTRAVGKAkamdLCLTGRMMDAAEAERAGLVSRVVPADKLldEALAA 192
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
11-253 1.41e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 90.10  E-value: 1.41e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDINQGNWRLGAN 89
Cdd:PRK06494    6 STVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGdKAFSAGNDLKEQAAGGKRGWPESGFG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSEYMLNyvmatysKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGAsyfLSRLPGFFGEYVG 169
Cdd:PRK06494   86 GLTSRFDLD-------KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGG---LHRLPRQIGLKRA 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 170 ----LTGARLDGAEMLACGLATHFVPSTrltalEADLCRinsndPTFASTILDAYTQHPRLKQQSAYRRLDVidrcfsrr 245
Cdd:PRK06494  156 mgmiLTGRRVTAREGLELGFVNEVVPAG-----ELLAAA-----ERWADDILACSPLSIRASKQAVYRGLEV-------- 217

                  ....*...
gi 1063743517 246 TVEEIISA 253
Cdd:PRK06494  218 SLEEAITA 225
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
5-199 2.63e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 86.64  E-value: 2.63e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVEEKS--SVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVR----D 78
Cdd:PRK08138    2 MSTATDVVLLERPadGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEFATagaiE 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  79 INQGNwrlganyfsSEYMLNyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
Cdd:PRK08138   82 MYLRH---------TERYWE-AIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLV 151
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063743517 159 RLPG-FFGEYVGLTGARLDGAEMLACGLATHFVP--STRLTALE 199
Cdd:PRK08138  152 RAVGkFKAMRMALTGCMVPAPEALAIGLVSEVVEdeQTLPRALE 195
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
11-195 4.40e-19

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 85.95  E-value: 4.40e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVvRDINQGNWR---- 85
Cdd:PRK05809    6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGeKAFVAGADISEM-KDLNEEEGRkfgl 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  86 LGANYFSSEYMLnyvmatySKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL--PGF 163
Cdd:PRK05809   85 LGNKVFRKLENL-------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIvgPGK 157
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1063743517 164 FGEYVgLTGARLDGAEMLACGLATHFVPSTRL 195
Cdd:PRK05809  158 AKELI-YTGDMINAEEALRIGLVNKVVEPEKL 188
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
11-211 4.69e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 85.79  E-value: 4.69e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFH-MISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDinQGNWRLGAN 89
Cdd:PRK09245    5 LLVERDGHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKDMRAR--VGAFGGSPA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSEYMLN---YVMATYSKAQVSI--LNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF 164
Cdd:PRK09245   83 DIRQGYRHGiqrIPLALYNLEVPVIaaVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMA 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 165 GEY-VGLTGARLDGAEMLACGLATHFVPSTRL--TALE-ADlcRINSNDPT 211
Cdd:PRK09245  163 RAAeMAFTGDAIDAATALEWGLVSRVVPADQLlpAARAlAE--RIAANPPH 211
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
5-217 1.39e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 84.38  E-value: 1.39e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDiNQGNW 84
Cdd:PRK07799    1 MEGGPHALVEQRGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKK-PPGDS 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  85 RLGANYFSS--EYMLNYVMATysKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR-LP 161
Cdd:PRK07799   80 FKDGSYDPSriDALLKGRRLT--KPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRqIP 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063743517 162 GFFGEYVGLTGARLDGAEMLACGLATHFVPS-TRLT-ALE-ADLcrINSNDPTFASTIL 217
Cdd:PRK07799  158 YTVACDLLLTGRHITAAEAKEIGLIGHVVPDgQALDkALElAEL--INANGPLAVQAIL 214
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
11-199 1.52e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 84.16  E-value: 1.52e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRL---- 86
Cdd:PRK07509    5 VSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSPGNAVKLLfkrl 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  87 --GANYFSseymlnyvmatyskaQVSI------------LNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVG 152
Cdd:PRK07509   85 pgNANLAQ---------------RVSLgwrrlpvpviaaLEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMA 149
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063743517 153 ASYFLSRLpgffgeyVG--------LTGARLDGAEMLACGLATHFVPSTRLTALE 199
Cdd:PRK07509  150 GTVSLRGL-------VRkdvareltYTARVFSAEEALELGLVTHVSDDPLAAALA 197
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
19-204 1.89e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 84.67  E-value: 1.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAA----VVRDINQGNWRLGANYFSSE 94
Cdd:PRK08260   14 IATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSAggntFDLDAPRTPVEADEEDRADP 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  95 YMLNY-------VMATYS--KAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFG 165
Cdd:PRK08260   94 SDDGVrdgggrvTLRIFDslKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQT 173
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063743517 166 --EYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADLCR 204
Cdd:PRK08260  174 alEWV-YSGRVFDAQEALDGGLVRSVHPPDELLPAARALAR 213
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
22-210 2.49e-18

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 83.75  E-value: 2.49e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAavVRDinqgnwRLGANYFSSEYMLNY- 99
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGdKAFCSGGDQK--VRG------DYGYIDDSGVHRLNVl 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 100 ----VMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG-FFGEYVGLTGAR 174
Cdd:TIGR01929  88 dvqrQIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGqKKAREIWFLCRQ 167
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063743517 175 LDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDP 210
Cdd:TIGR01929 168 YDAKQALDMGLVNTVVPLADLEKETVRWCReILQKSP 204
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
13-195 2.49e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 83.53  E-value: 2.49e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  13 VEEKSSVRILTLNRPKQlNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAV--VRDINQGN--WRLGA 88
Cdd:PRK07658    6 VRVEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFtsVTEAEQATelAQLGQ 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  89 NYFSSeymlnyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASyflSRLPgffgEYV 168
Cdd:PRK07658   85 VTFER-------VEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGT---QRLP----RYV 150
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1063743517 169 G--------LTGARLDGAEMLACGLATHFVPSTRL 195
Cdd:PRK07658  151 GkakalemmLTSEPITGAEALKWGLVNGVFPEETL 185
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
19-202 5.15e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 82.80  E-value: 5.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGD-------VAAVVRDINQGNWRLGAnyf 91
Cdd:PRK07468   15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDlgwmraqMTADRATRIEEARRLAM--- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  92 sseyMLNyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLT 171
Cdd:PRK07468   92 ----MLK-ALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFMS 166
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1063743517 172 GARLDGAEMLACGLATHFVPSTRL-TALEADL 202
Cdd:PRK07468  167 ARLFDAEEAVRLGLLSRVVPAERLdAAVEAEV 198
PLN02888 PLN02888
enoyl-CoA hydratase
11-199 1.76e-17

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 81.34  E-value: 1.76e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAvVRDINQGNWRLgany 90
Cdd:PLN02888   12 LVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTA-AEEVFKGDVKD---- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 fsSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF-GEYVG 169
Cdd:PLN02888   87 --VETDPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANrAREVS 164
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRL--TALE 199
Cdd:PLN02888  165 LTAMPLTAETAERWGLVNHVVEESELlkKARE 196
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
22-235 2.77e-17

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 80.89  E-value: 2.77e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQlNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDV-AAVVRDINQGNWRLGANYFSSE-YMLN 98
Cdd:PRK03580   16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGeKFFSAGWDLkAAAEGEAPDADFGPGGFAGLTEiFDLD 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 yvmatysKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFL-SRLPGFFGEYVGLTGARLDG 177
Cdd:PRK03580   95 -------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLpKRLPPAIANEMVMTGRRMDA 167
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063743517 178 AEMLACGLATHFVPSTRLTALEADLCR-INSNDPTFASTILDAYTQHPRLKQQSAYRRL 235
Cdd:PRK03580  168 EEALRWGIVNRVVPQAELMDRARELAQqLVNSAPLAIAALKEIYRETSEMPVEEAYRYI 226
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
1-159 4.27e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 80.08  E-value: 4.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASqsqVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSvKLVILKGHGRAFCAGGDVAAVVRDIN 80
Cdd:PRK07659    1 VTSKMES---VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSA-HIVVLRGNGRGFSAGGDIKMMLSSND 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063743517  81 QGNWRLGANYFSSEYMLNYVMatySKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR 159
Cdd:PRK07659   77 ESKFDGVMNTISEIVVTLYTM---PKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQK 152
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
8-162 6.78e-17

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 79.43  E-value: 6.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   8 QSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGD--------VAAVVRDI 79
Cdd:PRK09674    1 MSELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADlnemaekdLAATLNDP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  80 NQGNW-RLGAnyfsseymlnyvmatYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
Cdd:PRK09674   81 RPQLWqRLQA---------------FNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLI 145

                  ....
gi 1063743517 159 RLPG 162
Cdd:PRK09674  146 RSVG 149
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
11-200 7.26e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 79.38  E-value: 7.26e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDV----AAVVRDINQGnwrL 86
Cdd:PRK05870    5 VLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLtalgAAPGRPAEDG---L 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  87 GANYFSseYMlnyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGffGE 166
Cdd:PRK05870   82 RRIYDG--FL---AVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVG--PQ 154
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063743517 167 YVG---LTGARLDGAEMLACGLATHFVPSTRLTALEA 200
Cdd:PRK05870  155 VARaalLFGMRFDAEAAVRHGLALMVADDPVAAALEL 191
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
11-231 2.94e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 77.75  E-value: 2.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDpsVKLVILKGHGRAFCAGGDVA-AVVRDinqgnwrlgan 89
Cdd:PRK08150    4 VSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDHFCAGLDLSeLRERD----------- 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 yfSSEYMLNYVM--ATYSKAQ------VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLP 161
Cdd:PRK08150   71 --AGEGMHHSRRwhRVFDKIQygrvpvIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLI 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063743517 162 GF--FGEYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADLC-RINSNDPTFASTILDAYtqhPRLKQQSA 231
Cdd:PRK08150  149 GVarMTDMM-LTGRVYDAQEGERLGLAQYLVPAGEALDKAMELArRIAQNAPLTNFAVLNAL---PRIADMSA 217
PLN02600 PLN02600
enoyl-CoA hydratase
17-210 8.69e-16

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 76.38  E-value: 8.69e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGH-GRAFCAGGDVAaVVRDINQGNWRLGANYFSSEY 95
Cdd:PLN02600    3 SGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSvPGVFCAGADLK-ERRKMSPSEVQKFVNSLRSTF 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  96 MLnyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASyflSRLPGFFGEYVG----LT 171
Cdd:PLN02600   82 SS---LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGT---QRLPRLVGRSRAkeliFT 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063743517 172 GARLDGAEMLACGLATHFVPS--TRLTALEAdLCRINSNDP 210
Cdd:PLN02600  156 GRRIGAREAASMGLVNYCVPAgeAYEKALEL-AQEINQKGP 195
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
5-197 9.15e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 76.67  E-value: 9.15e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVE-EKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDV----AAVVRDI 79
Cdd:PRK06210    1 DMAYDAVLYEvADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMgelqTIDPSDG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  80 NQGNW--RLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFL 157
Cdd:PRK06210   81 RRDTDvrPFVGNRRPDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWIL 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063743517 158 SRLPGFFGEY-VGLTGARLDGAEMLACGLATHFVPSTRLTA 197
Cdd:PRK06210  161 PRLVGHANALdLLLSARTFYAEEALRLGLVNRVVPPDELME 201
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
11-203 1.54e-15

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 75.82  E-value: 1.54e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGN------- 83
Cdd:PRK09120   10 VKVEVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEYFRETDAQPeilqeri 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  84 -------WRLganyfsseymlnyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYF 156
Cdd:PRK09120   90 rreaygwWRR--------------LRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKA 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1063743517 157 LSRLPGFFGE-YVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLC 203
Cdd:PRK09120  156 MADTVGHRDAlYYIMTGETFTGRKAAEMGLVNESVPLAQLRARTRELA 203
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
9-185 1.89e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 75.42  E-value: 1.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   9 SQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDvaavvrdINQ--GNWRL 86
Cdd:PRK07511    3 AELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGN-------LNRllENRAK 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  87 GANY--FSSEYMLNYVMA--TYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSR-LP 161
Cdd:PRK07511   76 PPSVqaASIDGLHDWIRAirAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARaLP 155
                         170       180
                  ....*....|....*....|....
gi 1063743517 162 GFFGEYVGLTGARLDGAEMLACGL 185
Cdd:PRK07511  156 RQLATELLLEGKPISAERLHALGV 179
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-202 2.90e-15

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 74.98  E-value: 2.90e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEEKSS-VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDvaavVRDI 79
Cdd:PRK08139    2 MAPAAATEAPLLLREDRDgVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHD----LKEM 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  80 NQGNwrlGANYFS------SEYMLNyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLF---PD 150
Cdd:PRK08139   78 RAAR---GLAYFRalfarcSRVMQA--IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPM 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063743517 151 VGASYFLSRLPGFfgEYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADL 202
Cdd:PRK08139  153 VALSRNVPRKQAM--EML-LTGEFIDAATAREWGLVNRVVPADALDAAVARL 201
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
5-182 3.17e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 74.95  E-value: 3.17e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSqVLVEEKSSVRILTLNRPKQLNALSFHMiSRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNW 84
Cdd:PRK08140    1 MMYET-ILLAIEAGVATLTLNRPDKLNSFTREM-HRELREALDQVEDDGARALLLTGAGRGFCAGQDLADRDVTPGGAMP 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  85 RLGA---NYFSSEYMLnyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLP 161
Cdd:PRK08140   79 DLGEsieTFYNPLVRR---LRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLV 155
                         170       180
                  ....*....|....*....|.
gi 1063743517 162 GFfgeyvgltgARLDGAEMLA 182
Cdd:PRK08140  156 GM---------ARALGLALLG 167
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
19-216 4.42e-15

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 74.62  E-value: 4.42e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQgnwrlganyFSSEYMLN 98
Cdd:PRK08258   27 VATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHEIIGPLTK---------MDMPELLA 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 YVMAT--YSKAQ-------VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLF-PDVGASYFLSRLpgffgeyV 168
Cdd:PRK08258   98 FTRMTgdLVKAMracpqpiIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRI-------I 170
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1063743517 169 GL--------TGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFASTI 216
Cdd:PRK08258  171 GQgrasellyTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPTFAHGM 226
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
9-210 5.50e-15

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 73.96  E-value: 5.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   9 SQVLVEEKSSVRILTLNRPKqLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLGA 88
Cdd:PRK06495    4 SQLKLEVSDHVAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDVIKGPGDLRAH 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  89 NYFSSEymLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLfpdVGASYFLSRL-PGFFGEY 167
Cdd:PRK06495   83 NRRTRE--CFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLfGHSLTRR 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063743517 168 VGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDP 210
Cdd:PRK06495  158 MMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAReIASKSP 201
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
16-187 1.08e-14

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 73.40  E-value: 1.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  16 KSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAV--------VRDINQGNWRLG 87
Cdd:PLN02664   15 NSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLnsiseqssSGDRGRSGERLR 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  88 ANYfssEYMLNYVMATYS--KAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGAsyfLSRLPGFFG 165
Cdd:PLN02664   95 RKI---KFLQDAITAIEQcrKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVG 168
                         170       180
                  ....*....|....*....|....*.
gi 1063743517 166 ----EYVGLTGARLDGAEMLACGLAT 187
Cdd:PLN02664  169 ygnaMELALTGRRFSGSEAKELGLVS 194
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
11-195 4.45e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 71.31  E-value: 4.45e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLGANY 90
Cdd:PRK07260    4 IIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEMKRAVDEDDVQSLVKI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFF-GEYVG 169
Cdd:PRK07260   84 AELVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNrATHLA 163
                         170       180
                  ....*....|....*....|....*.
gi 1063743517 170 LTGARLDGAEMLACGLATHFVPSTRL 195
Cdd:PRK07260  164 MTGEALTAEKALEYGFVYRVAESEKL 189
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
4-185 5.03e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 71.54  E-value: 5.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   4 EMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQ-G 82
Cdd:PRK06142    1 MMTTYESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQlG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  83 NWRLGAN--YFSSEYM-----LNYVmATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGAsy 155
Cdd:PRK06142   81 KDGLARPrtDLRREILrlqaaINAV-ADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGS-- 157
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1063743517 156 fLSRLPGFFGEYV----GLTGARLDGAEMLACGL 185
Cdd:PRK06142  158 -LQRLPRIIGDGHlrelALTGRDIDAAEAEKIGL 190
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
4-204 1.80e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 69.64  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   4 EMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAvVRDINQG 82
Cdd:PRK06144    3 MTTSTDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGdKAFVAGTDIAQ-FRAFSTA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  83 nwRLGANYfssEYMLNYVMATYSKAQV---SILNGIVMGGGAGVSVHGRFRIATENTVFAMPeTALGLFPDVGASYfLSR 159
Cdd:PRK06144   82 --EDAVAY---ERRIDRVLGALEQLRVptiAAIAGACVGGGAAIAAACDLRIATPSARFGFP-IARTLGNCLSMSN-LAR 154
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1063743517 160 LPGFFG----EYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCR 204
Cdd:PRK06144  155 LVALLGaarvKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAE 203
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
1-195 4.05e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 69.09  E-value: 4.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEE-KSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGD--VAAVVR 77
Cdd:PRK05864    1 VAGYRSTMSLVLVDHpRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADhkSAGVVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  78 DInQGNWRLGANYFSSEYMLNYVMATYSKAQ--VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLF-PDVGAS 154
Cdd:PRK05864   81 HV-EGLTRPTYALRSMELLDDVILALRRLHQpvIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLS 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1063743517 155 YFLSRLPGFFGEY-VGLTGARLDGAEMLACGLATHFVPSTRL 195
Cdd:PRK05864  160 YLLPRAIGSSRAFeIMLTGRDVDAEEAERIGLVSRQVPDEQL 201
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
9-213 4.17e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 68.61  E-value: 4.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   9 SQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPS-VKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLG 87
Cdd:PRK05981    4 KKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAGRGFCTGANLQGRGSGGRESDSGGD 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  88 ANYfSSEYMLNYVMATYSKAQ---VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG-F 163
Cdd:PRK05981   84 AGA-ALETAYHPFLRRLRNLPcpiVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGkA 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063743517 164 FGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFA 213
Cdd:PRK05981  163 RAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVA 212
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
11-205 1.53e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 67.67  E-value: 1.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRD-----INQGNWR 85
Cdd:PRK12478    7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGGGFQHwgeamMTDGRWD 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  86 LGANYF---SSEYMLNY-VMATY--SKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETAL-GLFPdvgASYFLS 158
Cdd:PRK12478   87 PGKDFAmvtARETGPTQkFMAIWraSKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYL---TGMWLY 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063743517 159 RLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTA----LEADLCRI 205
Cdd:PRK12478  164 RLSLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLEArvaeVATELARI 214
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
10-213 4.44e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 66.14  E-value: 4.44e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  10 QVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDV--AAVVRDINQGN---- 83
Cdd:PRK08290    5 YVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLgsGTPGRDRDPGPdqhp 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  84 --WRLGANYFS--------SEYMLNYVMATY-----SKAQVSilnGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLf 148
Cdd:PRK08290   85 tlWWDGATKPGveqryareWEVYLGMCRRWRdlpkpTIAQVQ---GACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI- 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 149 pdVGASYFLSrlPGFFG-----EYVgLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRINSNDPTFA 213
Cdd:PRK08290  161 --PGVEYFAH--PWELGprkakELL-FTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFG 225
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
22-197 1.33e-11

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 64.44  E-value: 1.33e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVA----AVVRDINQgnwRLGANYFSSEYMl 97
Cdd:PRK05674   19 LWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLAwmqqSADLDYNT---NLDDARELAELM- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  98 nYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDG 177
Cdd:PRK05674   95 -YNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDG 173
                         170       180
                  ....*....|....*....|
gi 1063743517 178 AEMLACGLATHFVPSTRLTA 197
Cdd:PRK05674  174 RRARELGLLAESYPAAELEA 193
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
11-192 1.42e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 64.21  E-value: 1.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDINQGNWRLGANY 90
Cdd:PRK06563    1 VSRERRGHVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVAPKLAAGGFPFPEGG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMlnyVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGfFGE---Y 167
Cdd:PRK06563   81 IDPWGT---VGRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAG-WGNamrY 156
                         170       180
                  ....*....|....*....|....*
gi 1063743517 168 VgLTGARLDGAEMLACGLATHFVPS 192
Cdd:PRK06563  157 L-LTGDEFDAQEALRLGLVQEVVPP 180
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
13-202 1.69e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 63.78  E-value: 1.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  13 VEEKSSVRILTLNRPKQlNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAF-CAGGDVAAVVrDINQGNWRLGANYF 91
Cdd:PRK09076    7 LEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFfSAGADLNLFA-DGDKAVAREMARRF 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  92 SSEYmlnyvmATYSKAQ-VSI--LNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLpgffgeyV 168
Cdd:PRK09076   85 GEAF------EALSAFRgVSIaaINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWL-------V 151
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1063743517 169 G--------LTGARLDGAEMLACGLATHFVPstRLTALEADL 202
Cdd:PRK09076  152 GegwakrmiLCGERVDAATALRIGLVEEVVE--KGEAREAAL 191
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
11-210 3.24e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 63.09  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRD---INQGNWRLG 87
Cdd:PRK08252    5 VLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFARGerpSIPGRGFGG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  88 anyfsseymlnYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFL-SRLPGFFGE 166
Cdd:PRK08252   85 -----------LTERPPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLpRRIPYHIAM 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1063743517 167 YVGLTGARLDGAEMLACGLATHFVPSTrlTALEADLC---RINSNDP 210
Cdd:PRK08252  154 ELALTGDMLTAERAHELGLVNRLTEPG--QALDAALElaeRIAANGP 198
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
11-187 1.24e-10

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 61.24  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVrdiNQGNWRLGANY 90
Cdd:PRK07827    8 VRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAG---GGGGDPYDAAV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSEYMLNYVMATYS--KAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRL-PGFFGEY 167
Cdd:PRK07827   85 ARAREMTALLRAIVElpKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLsPRAAARY 164
                         170       180
                  ....*....|....*....|
gi 1063743517 168 VgLTGARLDGAEMLACGLAT 187
Cdd:PRK07827  165 Y-LTGEKFGAAEAARIGLVT 183
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
11-185 3.91e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 59.81  E-value: 3.91e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSS---VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDV----AAVVRDINQGN 83
Cdd:PRK06023    5 ILVERPGAhpgVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMqdflAAAMGGTSFGS 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  84 WRLganyfssEYMlnYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF 163
Cdd:PRK06023   85 EIL-------DFL--IALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGH 155
                         170       180
                  ....*....|....*....|...
gi 1063743517 164 FGEYVGLT-GARLDGAEMLACGL 185
Cdd:PRK06023  156 QRAFALLAlGEGFSAEAAQEAGL 178
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
7-198 5.68e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 59.28  E-value: 5.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   7 SQSQVLVEEKSSVRiLTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRdINQGNWR 85
Cdd:PRK06143    6 AHAGVTRDDRGVAT-LTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGeKAFIGGADIKEMAT-LDQASAE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  86 lgaNYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLfPDVGASYFLSRLPGFF- 164
Cdd:PRK06143   84 ---AFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWAr 159
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1063743517 165 GEYVGLTGARLDGAEMLACGLATHFVPSTRLTAL 198
Cdd:PRK06143  160 TRWLLLTGETIDAAQALAWGLVDRVVPLAELDAA 193
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
1-197 7.38e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 59.29  E-value: 7.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   1 MAVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIN 80
Cdd:PRK08272    2 RPVDLDNLKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAYAEGSS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  81 QGNW-------RLGANYFSSE---YMLNYVM-----------ATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENT--- 136
Cdd:PRK08272   82 SGGGggaypgkRQAVNHLPDDpwdPMIDYQMmsrfvrgfmslWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAkig 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063743517 137 -----VFAMPETALGLFpDVGASYfLSRLPgffgeyvgLTGARLDGAEMLACGLATHFVPSTRLTA 197
Cdd:PRK08272  162 ypptrVWGVPATGMWAY-RLGPQR-AKRLL--------FTGDCITGAQAAEWGLAVEAVPPEELDE 217
PLN02921 PLN02921
naphthoate synthase
22-211 1.90e-09

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 58.26  E-value: 1.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDinqgnwrlgaNYFSSEYM--LN 98
Cdd:PLN02921   80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGtKAFCSGGDQAVRGKD----------GYVGPDDAgrLN 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 YV-----MATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFpDVG-ASYFLSRLpgffgeyVGLTG 172
Cdd:PLN02921  150 VLdlqiqIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARL-------VGQKK 221
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1063743517 173 AR--------LDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDPT 211
Cdd:PLN02921  222 ARemwflarfYTASEALKMGLVNTVVPLDELEGETVKWCReILRNSPT 269
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
19-199 2.09e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 57.67  E-value: 2.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKqLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDV---------AAVVrDINQGNwrlgAN 89
Cdd:PRK07938   12 IAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIkelqatpgfTALI-DANRGC----FA 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  90 YFSSEYMLnyvmatySKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLfpdVGASYFLSRL-PGFFGEYV 168
Cdd:PRK07938   86 AFRAVYEC-------AVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGA---LGAATHLQRLvPQHLMRAL 155
                         170       180       190
                  ....*....|....*....|....*....|...
gi 1063743517 169 GLTGARLDGAEMLACGLATHFVPSTRL--TALE 199
Cdd:PRK07938  156 FFTAATITAAELHHFGSVEEVVPRDQLdeAALE 188
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
7-210 2.10e-09

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 57.73  E-value: 2.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   7 SQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEdPSVKLVILK--GHGRAFCAGGDVaavvRDINQGNw 84
Cdd:PRK11423    2 SMQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILRapSGSKVWSAGHDI----HELPSGG- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  85 RLGANYFSSEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGL-FPDVGASYFLSRLPGF 163
Cdd:PRK11423   76 RDPLSYDDPLRQILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVpYNLSGILNFTNDAGFH 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1063743517 164 FGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDP 210
Cdd:PRK11423  156 IVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHhISEKAP 203
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
11-75 4.27e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 56.83  E-value: 4.27e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAV 75
Cdd:PRK08259    5 VRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAV 69
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
22-128 6.70e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 56.18  E-value: 6.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVaAVVRDINqGNWRLGANYFSSEYMLNYVM 101
Cdd:PRK07327   25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDL-ALVEEMA-DDFEVRARVWREARDLVYNV 102
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1063743517 102 ATYSKAQVSILNGIVMGGG------AGVSVHGR 128
Cdd:PRK07327  103 INCDKPIVSAIHGPAVGAGlvaallADISIAAK 135
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
11-206 1.73e-08

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 54.69  E-value: 1.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDpsVKLVILKGHGRAFCAGGDvaavVRDINQGNWRLGANY 90
Cdd:PRK07112    6 IRVRQQGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPEVFCFGAD----FSAIAEKPDAGRADL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  91 FSSE--YMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPdvgASY--FLSRLPGFF-G 165
Cdd:PRK07112   80 IDAEplYDLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP---ACVlpFLIRRIGTQkA 156
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063743517 166 EYVGLTGARLDGAEMLACGLATHFVPSTRlTALEADLCRIN 206
Cdd:PRK07112  157 HYMTLMTQPVTAQQAFSWGLVDAYGANSD-TLLRKHLLRLR 196
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
5-191 6.34e-08

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 53.05  E-value: 6.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   5 MASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGdVAAVVRDINQGnw 84
Cdd:PRK07110    1 MMMKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGG-TQEGLLSLQTG-- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  85 rlganyfsseYMLNYVMATYSKAQ------VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLS 158
Cdd:PRK07110   78 ----------KGTFTEANLYSLALncpipvIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILP 147
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1063743517 159 RLPGF-FGEYVGLTGARLDGAEMLACGLATHFVP 191
Cdd:PRK07110  148 EKLGLaLGQEMLLTARYYRGAELKKRGVPFPVLP 181
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
22-211 1.09e-07

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 52.59  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAavVRdinqGNwrlgANYFSSEYM--LN 98
Cdd:PRK07396   26 ITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGdKAFCSGGDQK--VR----GY----GGYVDDDGVprLN 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 YV-----MATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFpD--VGASYfLSRLpgffgeyVGLT 171
Cdd:PRK07396   96 VLdlqrlIRTCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DggYGASY-LARI-------VGQK 166
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1063743517 172 GAR--------LDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDPT 211
Cdd:PRK07396  167 KAReiwflcrqYDAQEALDMGLVNTVVPLADLEKETVRWCReMLQNSPM 215
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
7-162 3.28e-07

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 52.15  E-value: 3.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517   7 SQSQVLVEEKSSVRILTLNRPK-QLNALSFHMISRLLQLFLAFEEDPSVK-LVILKGHGRAFCAGGDV--------AAVV 76
Cdd:TIGR02441  11 ARTHRHYEVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIqmiaacktAQEV 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  77 RDINQGnwrlganyfsSEYMLNYvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATEN--TVFAMPETALGLFPDVGAS 154
Cdd:TIGR02441  91 TQLSQE----------GQEMFER-IEKSQKPIVAAISGSCLGGGLELALACHYRIATKDrkTLLGLPEVMLGLLPGAGGT 159

                  ....*...
gi 1063743517 155 YFLSRLPG 162
Cdd:TIGR02441 160 QRLPKLTG 167
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
19-186 3.93e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 47.71  E-value: 3.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRPKQLNALSFHMISRLLQLFLAFEEDpSVKLVILKGHGRAFCAGGDVAAVVrdinqgnwrLGANYFSSEYMLN 98
Cdd:PRK07854   10 VLTIELQRPERRNALNAELCEELREAVRKAVDE-SARAIVLTGQGTVFCAGADLSGDV---------YADDFPDALIEML 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 YVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDvgaSYFLSRLPGFFG----EYVGLTGAR 174
Cdd:PRK07854   80 HAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGggraRAMLLGAEK 156
                         170
                  ....*....|..
gi 1063743517 175 LDGAEMLACGLA 186
Cdd:PRK07854  157 LTAEQALATGMA 168
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
19-211 4.91e-06

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 47.51  E-value: 4.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRIlTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG------RAFCAGGDVAAVVRDINQGNWRLGanyfs 92
Cdd:COG0447    29 ARI-AINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGpskdggWAFCSGGDQRVRGRGGYVYEDGVG----- 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  93 seyMLNYV-----MATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAmpETAlglfPDV-------GASYfLSRL 160
Cdd:COG0447   103 ---RLNILevqrlIRFMPKPVIAMVAGWAIGGGHVLHVVCDLTIASENARFG--QTG----PDVgsfdagyGSAY-LARQ 172
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 161 pgffgeyVGLTGAR--------LDGAEMLACGLATHFVPSTRLTALEADLCR-INSNDPT 211
Cdd:COG0447   173 -------VGQKKAReiwflcrqYSAQEALEMGLVNKVVPHAELEEEAVEWAReILEKSPT 225
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
109-162 2.98e-05

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 46.01  E-value: 2.98e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063743517 109 VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPG 162
Cdd:PRK11730  106 VAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
21-195 4.97e-05

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 44.49  E-value: 4.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  21 ILTLNRpKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGR--AFCAGGDVAAVVRDinQGNWRLGANYFSSEYMLN 98
Cdd:PLN03214   24 VVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRrdVFTAGNDIAELYAP--KTSAARYAEFWLTQTTFL 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  99 YVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGL-FPDVGASYFLSRLPG-FFGEYVGLTGARLD 176
Cdd:PLN03214  101 VRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDrKVAESLLLRGRLVR 180
                         170
                  ....*....|....*....
gi 1063743517 177 GAEMLACGLATHFVPSTRL 195
Cdd:PLN03214  181 PAEAKQLGLIDEVVPAAAL 199
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
19-199 1.49e-04

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 43.73  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  19 VRILTLNRP-KQLNALSFHMISRLLQLFLAFEEDPSVK-LVILKGHGRAFCAGGDV--------AAVVRDINqgnwRLGA 88
Cdd:PRK11154   16 IAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKgVVFISGKPDNFIAGADInmlaacktAQEAEALA----RQGQ 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517  89 NYFSSeymlnyvMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATEN--TVFAMPETALGLFPDVGASYFLSRLpgffge 166
Cdd:PRK11154   92 QLFAE-------IEALPIPVVAAIHGACLGGGLELALACHYRVCTDDpkTVLGLPEVQLGLLPGSGGTQRLPRL------ 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1063743517 167 yVG--------LTGARLDGAEMLACGLATHFVPSTRL--TALE 199
Cdd:PRK11154  159 -IGvstaldmiLTGKQLRAKQALKLGLVDDVVPHSILleVAVE 200
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
109-191 5.34e-04

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 41.44  E-value: 5.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063743517 109 VSILNGIVMGGG--AGVSVHgrFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVGLTGARLDGAEMLACGL 185
Cdd:PRK08788  125 IALVQGDALGGGfeAALSHH--TIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPkLAEELILSGKLYTAEELHDMGL 202

                  ....*.
gi 1063743517 186 ATHFVP 191
Cdd:PRK08788  203 VDVLVE 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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