|
Name |
Accession |
Description |
Interval |
E-value |
| GAS2 |
smart00243 |
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain |
3227-3299 |
1.94e-43 |
|
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain
Pssm-ID: 128539 Cd Length: 73 Bit Score: 153.37 E-value: 1.94e-43
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1143463347 3227 EKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCRAKG 3299
Cdd:smart00243 1 DKIDDEVKRIVEDCKCPTKFQVEKISEGKYRFGDSQILRLVRILRSTVMVRVGGGWETLDEYLLKHDPCRAKG 73
|
|
| GAS2 |
pfam02187 |
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members ... |
3229-3297 |
1.64e-33 |
|
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members and Gas2 family members. The GAR domain comprises around 57 amino acids and has been shown to bind to microtubules.
Pssm-ID: 460480 Cd Length: 69 Bit Score: 124.63 E-value: 1.64e-33
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1143463347 3229 ITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCRA 3297
Cdd:pfam02187 1 LDDEVRRIVAQCTCPTKFPVEKVGEGKYRFGDSQKLVFVRILRSHVMVRVGGGWDTLEEYLLKHDPCRA 69
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2270-2475 |
4.01e-18 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 85.96 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHlAATVRQP 2349
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSST---DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLENLMLQMGKLAStIAQLTAWMDKTRATLKDIAPPKnavNLRDIEIAQCKLVVLSNDIH 2429
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKELEEELE 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1143463347 2430 AHQDSVNAVNRAAQKYIQTSG-ALDAETSDSLKSMNLKWEDIQKVLE 2475
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHpDADEEIEEKLEELNERWEELLELAE 203
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2494-2699 |
2.92e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 83.26 E-value: 2.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2494 EVEKWQRWLEETESALLSTKPtGGLPETAEFQLDEFKALKLDVEHNASPLEAhLHATEQHLKEEPQDADTWLSKTHGAMK 2573
Cdd:cd00176 8 DADELEAWLSEKEELLSSTDY-GDDLESVEALLKKHEALEAELAAHEERVEA-LNELGEQLIEEGHPDAEEIQERLEELN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2574 TKWNKVKELLVDREKKLQVAYEQAVALESALnDMEDWIIAAERKLTDQPSISRLPDViEKQLAEHESWMEEVAGRKMAMT 2653
Cdd:cd00176 86 QRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLGKDLESV-EELLKKHKELEEELEAHEPRLK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1143463347 2654 KHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQL 2699
Cdd:cd00176 164 SLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKL 209
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2818-3017 |
4.45e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 82.88 E-value: 4.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2818 FEESMNDLESWVDDELERYQKAEHEpvfADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAK 2897
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYG---DDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2898 ERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDaKTHALLDWLAVEEQKLKASG-----------LDEVEGVKQEMDEAKG 2966
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDlgkdlesveelLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 2967 RYQECLKKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLE 3017
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1390-1607 |
1.62e-15 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 78.26 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1390 QQGKVEDAYRALLNWLEETEEMMeNRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKkaL 1469
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELL-SSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE--I 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1470 GNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIpLDSWLQSADKRLQALAKVPiTVEKAEEMIGEQEALQDEL 1549
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALASEDLGK-DLESVEELLKKHKELEEEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1143463347 1550 EHKSDDLKDVLEIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFL 1607
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
711-1431 |
5.17e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 5.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 711 VEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKS 790
Cdd:TIGR02168 248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 791 RFGGVDKALEKLKgilEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNS 870
Cdd:TIGR02168 328 LESKLDELAEELA---ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 871 AENELElaaPIAAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEELKKKPDAELKKKLELLYQKWPKALGAARDRK 950
Cdd:TIGR02168 405 LEARLE---RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 951 DLVSKAGDLVkqfgDQVQALEQRLQGDQAELDELLASDK---AHDPEVCDALKL-------VELTMARRLAD--VDALNA 1018
Cdd:TIGR02168 482 RELAQLQARL----DSLERLQENLEGFSEGVKALLKNQSglsGILGVLSELISVdegyeaaIEAALGGRLQAvvVENLNA 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1019 VMNRIESSAPgpdaNRLRRRADTLSDDAKGMAKKARTAADLAQrkqglAKKFERLCDEVSQFTENQKAEIQD-----AIE 1093
Cdd:TIGR02168 558 AKKAIAFLKQ----NELGRVTFLPLDSIKGTEIQGNDREILKN-----IEGFLGVAKDLVKFDPKLRKALSYllggvLVV 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1094 KDLLNAERVQSKLNKI-------DDFWS-----------------SNSRELKNVGDEI-----KIDATPEDAQAVDTKLA 1144
Cdd:TIGR02168 629 DDLDNALELAKKLRPGyrivtldGDLVRpggvitggsaktnssilERRREIEELEEKIeeleeKIAELEKALAELRKELE 708
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1145 ELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKINSLVAEIADLDPIGRS-RDELQKQKKEVVELAGDLGSAQ 1223
Cdd:TIGR02168 709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEElEERLEEAEEELAEAEAEIEELE 788
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1224 TKMLELGAEWEaALGAGIVAQpvfemnRAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIAKD- 1302
Cdd:TIGR02168 789 AQIEQLKEELK-ALREALDEL------RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEi 861
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1303 EALQGAPSQLLDP-KQVSEKVRQLKESLKPVGEKMDAFNTDckllIKTAgpESDTKELDSLLKKVGDAYSDVVGKVSDKE 1381
Cdd:TIGR02168 862 EELEELIEELESElEALLNERASLEEALALLRSELEELSEE----LREL--ESKRSELRRELEELREKLAQLELRLEGLE 935
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1382 MSVDaavQQQGKVEDAYRALLnwleetEEMMENRKKPSADAKVAKAQLHD 1431
Cdd:TIGR02168 936 VRID---NLQERLSEEYSLTL------EEAEALENKIEDDEEEARRRLKR 976
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1823-2044 |
3.22e-13 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 71.71 E-value: 3.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1823 QSRAVLDDLQYLIEWFSAArERILEGAPPSLDLEVLKSQLKHQRITNEEASANKVQFRNVAGEAKKVARqlgmEGNEANE 1902
Cdd:cd00176 1 KLQQFLRDADELEAWLSEK-EELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIE----EGHPDAE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1903 KISDTVDEGKELVEEVMALCADRTETLERALALMEQLtSQFDELNKWLDQMDAELQASPSVTTATpaaELREMHDHNEEL 1982
Cdd:cd00176 76 EIQERLEELNQRWEELRELAEERRQRLEEALDLQQFF-RDADDLEQWLEEKEAALASEDLGKDLE---SVEELLKKHKEL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1143463347 1983 ARMVAAYRPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMM 2044
Cdd:cd00176 152 EEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
711-1285 |
4.42e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 4.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 711 VEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASA---MSSNDIGDQLATLDS 787
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 788 LKSRFGGVDKALEKLKG-ILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIG 866
Cdd:COG1196 307 LEERRRELEERLEELEEeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 867 TVNSAENE-LELAAPIAAESLKLADELKRAEELFQKLIENEGDvsLIRAKVAEELKKKPDAELKKKLELLYQKwpkALGA 945
Cdd:COG1196 387 ELLEALRAaAELAAQLEELEEAEEALLERLERLEEELEELEEA--LAELEEEEEEEEEALEEAAEEEAELEEE---EEAL 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 946 ARDRKDLVSKAgdlvKQFGDQVQALEQRLQGDQAELDELLASDKAHDPEVCDALKLVELTMARRLA-DVDALNAVMNRIE 1024
Cdd:COG1196 462 LELLAELLEEA----ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgAVAVLIGVEAAYE 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1025 SSAPGPDANRLRRRADTLSDDAkgmakkARTAADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDAIEKDLLNAERVQS 1104
Cdd:COG1196 538 AALEAALAAALQNIVVEDDEVA------AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1105 KLNKIDDFWSSNSRELKNVGDEIKIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGK 1184
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1185 INSLVAEIADLDPIGRSRDELQKQKKEVVELAGDLGSAQTKMLELGAEWEaalgagivaqpvfEMNRAATDELNKLAARA 1264
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL-------------LEEEELLEEEALEELPE 758
|
570 580
....*....|....*....|.
gi 1143463347 1265 GKRLAQREKKITETEDEIDKL 1285
Cdd:COG1196 759 PPDLEELERELERLEREIEAL 779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
24-874 |
6.51e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.56 E-value: 6.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 24 RIDEARFEAKSLMDEV-------IREESRLKtigaSVLKIEQEISAMRDDVRASgstddvgiSVDEVYETRRRVEDDYMQ 96
Cdd:PTZ00121 1088 RADEATEEAFGKAEEAkktetgkAEEARKAE----EAKKKAEDARKAEEARKAE--------DARKAEEARKAEDAKRVE 1155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 97 LLRQCQDLISFQNRLHAMNDEHSEQARRADEWLQMLQ-NDVEDVDQDPRFQRDEDrIQRIEELNRMA-AGGSSQLDDAEQ 174
Cdd:PTZ00121 1156 IARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEElRKAEDARKAEAARKAEE-ERKAEEARKAEdAKKAEAVKKAEE 1234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 175 ASRRLLTALEGTNVANDVRARHEELANLRRGKHQKVIDRlsqnmmeaASRKAEAEGVKQAVENLRQWSEQTAQRTRQPVQ 254
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK--------AEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 255 LpltELDLHEARKDEQvLHGEIENRLALIEELEKKAADVGDHASLAELQECKMKLKRSNSDLKGLRDnifdainglQTVN 334
Cdd:PTZ00121 1307 A---KKKAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA---------EKKK 1373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 335 SEGETLSRAVDSAGAKIRSARlpEAQSEVEALQDQADNLERITNNLCNIPNVTRTEPVIQKSKDLRKRVDSCAQELDARm 414
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKAD--EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK- 1450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 415 gKLAElESLDAEfdGAKNKLSSFIGAFDDELKGLEKVSIDK-EKLAEQRRQTQDLVDKHSEGNAILDDVEAIAQKVTAED 493
Cdd:PTZ00121 1451 -KKAE-EAKKAE--EAKKKAEEAKKADEAKKKAEEAKKADEaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 494 PSKTGSAQKSVGELGARLQRQASELKaRGDKINKLDSKATSFAESEAAVLGYIEKQKDQLSTgfpvPATKEGVKSQLLDL 573
Cdd:PTZ00121 1527 AKKAEEAKKADEAKKAEEKKKADELK-KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK----KAEEARIEEVMKLY 1601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 574 ERMNKTGKEEQRRVDDARHSARELAREASVEKEVQDMNQREKKlldewedladqfdavrsRANKAEQVLNEcaqmEKYIG 653
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE-----------------EKKKAEELKKA----EEENK 1660
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 654 AKKnmlegigapSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLANEliadgGANVEELMKKMDRLNRKWHSLESGLD 733
Cdd:PTZ00121 1661 IKA---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE-----AKKAEELKKKEAEEKKKAEELKKAEE 1726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 734 ENAGRVEEAAKLGQELKDIQKELRKELGElesnvekasamssndigdqlatLDSLKSRFGGVDKALEKLKGILEATEELE 813
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEAKKDEEE----------------------KKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 814 VDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENE 874
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2380-2594 |
2.06e-12 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 69.01 E-value: 2.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2380 KLASTIAQLTAWMDKTRATLKDIAPPKNavnLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTSGALDAETSDS 2459
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDD---LESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2460 LKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGgEVEKWQRWLEETESALLSTKPtGGLPETAEFQLDEFKALKLDVEHN 2539
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDL-GKDLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 2540 ASPLEAHLHATEQHLKEEPQDADTWLSKTHGAMKTKWNKVKELLVDREKKLQVAY 2594
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
562-1327 |
7.43e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.10 E-value: 7.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 562 TKEGVKSQLLDLERMNKTGKE------EQRRVDDARHSARELAREASVEKEVQDMNQREKKLLDEWEDLADQFDAVR--S 633
Cdd:PTZ00121 1058 GKAEAKAHVGQDEGLKPSYKDfdfdakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARkaE 1137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 634 RANKAEQVLNecAQMEKYIGAKKNMLEG----IGAPSTEPGVAKANRAQIQSMKAEtegEKSALEHVNSLANELIADGGA 709
Cdd:PTZ00121 1138 DARKAEEARK--AEDAKRVEIARKAEDArkaeEARKAEDAKKAEAARKAEEVRKAE---ELRKAEDARKAEAARKAEEER 1212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 710 NVEELMKKMDRlnRKWHSLESGldENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLK 789
Cdd:PTZ00121 1213 KAEEARKAEDA--KKAEAVKKA--EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 790 SRFGGVDKALEKLKGILEATEELEvDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVN 869
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAE-EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 870 SAENELELAAPIAAESLKLADELKRAEELFQKLIENEgdvsliraKVAEELKKKpdAELKKKLEllyqkwpkalgAARDR 949
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK--------KKADELKKA--AAAKKKAD-----------EAKKK 1426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 950 KDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDELLASdKAHDPEVCDALKlveltmaRRLADVDALNAVMNRIESSAPG 1029
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK-KAEEAKKADEAK-------KKAEEAKKADEAKKKAEEAKKK 1498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1030 PDANRLRRRADTLSDDAKgMAKKARTAADLAQ----RKQGLAKKFE--RLCDEVSQFTENQKAEIQDAIEKDLLNAERVQ 1103
Cdd:PTZ00121 1499 ADEAKKAAEAKKKADEAK-KAEEAKKADEAKKaeeaKKADEAKKAEekKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1104 SKLNKIDDFWSSNSRELKNVGDEIKIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAG 1183
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1184 KINSLVAEIAdldpigrSRDELQKQKKEvvELAGDLGSAQTKMLELGAEWEAALGAGIVAQPVFEMNRAA-----TDELN 1258
Cdd:PTZ00121 1658 ENKIKAAEEA-------KKAEEDKKKAE--EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelkkAEEEN 1728
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 1259 KLAARAGKRLAQREKKITET----EDEIDKL-HADADQIVGALEAIAKDEALQGAPSQLLDPKQVSEKVRQLKE 1327
Cdd:PTZ00121 1729 KIKAEEAKKEAEEDKKKAEEakkdEEEKKKIaHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2050-2264 |
1.25e-11 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 66.70 E-value: 1.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2050 FGERLETLVANLQGAADRLRENEGISaDPSVLESRLAENRSIVESLRDKQNAYDALKQTASELLASAPEgdaAAGDVENK 2129
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP---DAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2130 LNRLEKLWKEIEREAVDRGVLLEDVLDKAKHFWsELDSCQKAVDDLRNRLElVEPATGHPEQLADQQEIMAQVASEMERA 2209
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALA-SEDLGKDLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 2210 RPRIEALSIAGKQLADYVPDDEKAVIENQVANVRGGFSTITGLFAEKKRDLIAAM 2264
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2270-2372 |
2.31e-11 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 62.73 E-value: 2.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHlAATVRQP 2349
Cdd:smart00150 3 FLRDADELEAWLEEKEQLLASE---DLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPD-AEEIEER 78
|
90 100
....*....|....*....|...
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLE 2372
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
207-875 |
2.58e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 70.15 E-value: 2.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 207 HQKVIDRLSQNMMEAASRKAEAEGVKQAVENLRQWSEQTAQRTRQPVQLPLTELDLHEARKD------------------ 268
Cdd:pfam15921 101 HEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmledsntqieqlrkmml 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 269 --EQVLHgeiENRLALIEELEKKAADVGDHASLAELQECKMK------LKRSNSDLKGLRDNIFDAINGLQTVNSEGETL 340
Cdd:pfam15921 181 shEGVLQ---EIRSILVDFEEASGKKIYEHDSMSTMHFRSLGsaiskiLRELDTEISYLKGRIFPVEDQLEALKSESQNK 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 341 -----------------SRAVDSAG--AKIRSAR--LPEAQSEVEALQDQADNLERITnnLCNIPNVTRTepVIQKSKDL 399
Cdd:pfam15921 258 ielllqqhqdrieqlisEHEVEITGltEKASSARsqANSIQSQLEIIQEQARNQNSMY--MRQLSDLEST--VSQLRSEL 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 400 RKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGLEKVSIDKEK-LAEQRRQTQDLVDKHSeGNAI 478
Cdd:pfam15921 334 REAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKeLSLEKEQNKRLWDRDT-GNSI 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 479 --------LDDVEAIAQKVTAedpskTGSAQKSvgELGARLQRQASELKARGDKINKLdSKATSFAESeaavlgyiekqk 550
Cdd:pfam15921 413 tidhlrreLDDRNMEVQRLEA-----LLKAMKS--ECQGQMERQMAAIQGKNESLEKV-SSLTAQLES------------ 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 551 dqlstgfpvpaTKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARELARE-ASVEKEVQDMNQREKKLLDEWEDLADQFD 629
Cdd:pfam15921 473 -----------TKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAiEATNAEITKLRSRVDLKLQELQHLKNEGD 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 630 AVRSRANKAEQVLNECAQMEKYIGAKK----NMLEGIGAPSTEPGVAKANRAQIQSmkaETEGEKSALEHVNSLANElia 705
Cdd:pfam15921 542 HLRNVQTECEALKLQMAEKDKVIEILRqqieNMTQLVGQHGRTAGAMQVEKAQLEK---EINDRRLELQEFKILKDK--- 615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 706 dGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATL 785
Cdd:pfam15921 616 -KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTT 694
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 786 DSLKSRFGGVDKALEKLKGILEATEELEVDATNRA-EIQEQLETTQKKADELERKIENVKKAALNAQNEG--LELEK-KL 861
Cdd:pfam15921 695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKhfLKEEKnKL 774
|
730
....*....|....
gi 1143463347 862 DELIGTVNSAENEL 875
Cdd:pfam15921 775 SQELSTVATEKNKM 788
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
637-850 |
3.95e-11 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 65.54 E-value: 3.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 637 KAEQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVaKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMK 716
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLESV-EALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 717 KMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQkELRKELGELEsnvekaSAMSSNDIGDQLATLDSLKSRFGGVD 796
Cdd:cd00176 80 RLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKE------AALASEDLGKDLESVEELLKKHKELE 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 797 KALEKLKGILEATEEL------EVDATNRAEIQEQLETTQKKADELERKIENVKKAALNA 850
Cdd:cd00176 153 EELEAHEPRLKSLNELaeelleEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
238-984 |
2.00e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 238 LRQWSEQTAQRTRQPVQLPLTELDLHEARKDEQVLHGEIENRLALIEELEKKAADVGD--HASLAELQECKMKLKRSNSD 315
Cdd:TIGR02168 231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKelYALANEISRLEQQKQILRER 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 316 LKGLRDNIFDAINGLQTVNSEGETLSRAVDSAGAKIRsarlpEAQSEVEALQDQADNLERITNNLcnipnVTRTEPVIQK 395
Cdd:TIGR02168 311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----ELKEELESLEAELEELEAELEEL-----ESRLEELEEQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 396 SKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGLEKVSIdKEKLAEQRRQTQDLVDKHSEG 475
Cdd:TIGR02168 381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL-QAELEELEEELEELQEELERL 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 476 NAILDDV-EAIAQKVTAEDPsktgsaqksvgelgarLQRQASELKARGDKINKLDSKATSFAESEAAVLgyieKQKDQLS 554
Cdd:TIGR02168 460 EEALEELrEELEEAEQALDA----------------AERELAQLQARLDSLERLQENLEGFSEGVKALL----KNQSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 555 TGFpvpatkeGVKSQLLDLERMNKTGKEEqrrVDDARHSARELAREASVEKEVQDMNQREKK-----LLDEWEDLADQFD 629
Cdd:TIGR02168 520 GIL-------GVLSELISVDEGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 630 AVRSRANKaEQVLNECAQMEKYIGAKKNMLEGIGApstepGVAKANR-AQIQSMKAETEGEKSALehvnSLANELIADGG 708
Cdd:TIGR02168 590 DREILKNI-EGFLGVAKDLVKFDPKLRKALSYLLG-----GVLVVDDlDNALELAKKLRPGYRIV----TLDGDLVRPGG 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 709 A-NVEELMKKMDRLNRKwhsleSGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAM---SSNDIGDQLAT 784
Cdd:TIGR02168 660 ViTGGSAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEleeLSRQISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 785 LDSLKSRFGGVDKALEKLKG-ILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDE 863
Cdd:TIGR02168 735 LARLEAEVEQLEERIAQLSKeLTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 864 LIGTVNSAENELElaapiaAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEElkKKPDAELKKKLELLYQKWPKAL 943
Cdd:TIGR02168 815 LNEEAANLRERLE------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL--EELIEELESELEALLNERASLE 886
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 1143463347 944 GAARDRKDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDEL 984
Cdd:TIGR02168 887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2466-3049 |
2.52e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 63.62 E-value: 2.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2466 KWEDIQKVlESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAE--FQLDEF-KALKLDVEHNASP 2542
Cdd:PTZ00121 1219 KAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEeaRKADELkKAEEKKKADEAKK 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2543 LEAHLHATEQHLKEEPQDADTWLSKTHGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQp 2622
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA- 1376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2623 siSRLPDVIEKQlAEHESWMEEvAGRKMAMTKHQASGVHmQYYCEKKDAIPIKNRLVSLKHRVE-KISGRTAERAKQLAV 2701
Cdd:PTZ00121 1377 --KKKADAAKKK-AEEKKKADE-AKKKAEEDKKKADELK-KAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAKK 1451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2702 TRDEVATWQDGLHDLEHF-ISDVLVKIAPEPNTTsslEKLKAKLEEVK----EAQRDVTAKQTLFDVTRKRGIGLAERAT 2776
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAkKADEAKKKAEEAKKA---DEAKKKAEEAKkkadEAKKAAEAKKKADEAKKAEEAKKADEAK 1528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2777 RSEYKQISMTNEKMS-KKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALV 2855
Cdd:PTZ00121 1529 KAEEAKKADEAKKAEeKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2856 DEESRRSAERKTKENGVKtvvkKADalmasgvDEKDSIAQAKERLVEKWNQVEEAAR-HRGNSIKEAEQAAEEFDAKTHA 2934
Cdd:PTZ00121 1609 AEEAKKAEEAKIKAEELK----KAE-------EEKKKVEQLKKKEAEEKKKAEELKKaEEENKIKAAEEAKKAEEDKKKA 1677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2935 LLDWLAVEEQKLKASGLDEVEGVKQEMDEAKGRYQECLKKGEEIlskcQPAAEpilRNWMRVVEARWKEVSEKVDEREFT 3014
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL----KKAEE---ENKIKAEEAKKEAEEDKKKAEEAK 1750
|
570 580 590
....*....|....*....|....*....|....*
gi 1143463347 3015 LLEQEQKAKEQNEQIEKlaKFAAQKREELNRMIEQ 3049
Cdd:PTZ00121 1751 KDEEEKKKIAHLKKEEE--KKAEEIRKEKEAVIEE 1783
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2270-2373 |
2.31e-08 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 54.25 E-value: 2.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLlkmSPVEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAaDAPPHLAATVRQP 2349
Cdd:pfam00435 6 FFRDADDLESWIEEKEALL---SSEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLI-DEGHYASEEIQER 81
|
90 100
....*....|....*....|....
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLEN 2373
Cdd:pfam00435 82 LEELNERWEQLLELAAERKQKLEE 105
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2743-3162 |
1.40e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2743 KLEEVKEAQ--RDVTAKQTLFDVTRKRGIGLAERATRSE-------YKQISMTNEKMSKKWAEMLKKLRDRLREAEQAV- 2812
Cdd:PTZ00121 1165 KAEEARKAEdaKKAEAARKAEEVRKAEELRKAEDARKAEaarkaeeERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKk 1244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2813 LEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALvdEESRRSAERKTKENGVKTVVKKADALMASGVDE-KD 2891
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEaKK 1322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2892 SIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFD-AKTHALLDWLAVEEQKLKASGLDEVEGVKQEMDEAKGRYQE 2970
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEaAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2971 CLKKGEEIlsKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQNEQIEKLAKFAAQKR--EELNRMIE 3048
Cdd:PTZ00121 1403 DKKKADEL--KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKkaDEAKKKAE 1480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 3049 QppAQDLDTMEQNICDFANLDSELREQQPEVDAACKSAKKGARNPAAEMLSTEWKKlwlDAMGLQSSLDNQKAllEEMKR 3128
Cdd:PTZ00121 1481 E--AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK---KADEAKKAEEKKKA--DELKK 1553
|
410 420 430
....*....|....*....|....*....|....
gi 1143463347 3129 LEGWKWEDWKeRYVEWNDHAKARVNDLFRRIDRL 3162
Cdd:PTZ00121 1554 AEELKKAEEK-KKAEEAKKAEEDKNMALRKAEEA 1586
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2494-2591 |
3.52e-07 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 50.79 E-value: 3.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2494 EVEKWQRWLEETEsALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTwLSKTHGAMK 2573
Cdd:smart00150 6 DADELEAWLEEKE-QLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEE-IEERLEELN 83
|
90
....*....|....*...
gi 1143463347 2574 TKWNKVKELLVDREKKLQ 2591
Cdd:smart00150 84 ERWEELKELAEERRQKLE 101
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2818-2919 |
1.28e-06 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 49.25 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2818 FEESMNDLESWVDdelERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAK 2897
Cdd:smart00150 3 FLRDADELEAWLE---EKEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 1143463347 2898 ERLVEKWNQVEEAARHRGNSIK 2919
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2925-3126 |
1.30e-06 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 52.06 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2925 AEEFDAKTHALLDWLAVEEQKLKASG-----------LDEVEGVKQEMDEAKGRYQECLKKGEEILSKCQPAAEPIlRNW 2993
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDygddlesvealLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEI-QER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2994 MRVVEARWKEVSEKVDEREfTLLEQEQKAKEQNEQIEKLAKFAAQKREELNRmieQPPAQDLDTMEQNICDFANLDSELR 3073
Cdd:cd00176 81 LEELNQRWEELRELAEERR-QRLEEALDLQQFFRDADDLEQWLEEKEAALAS---EDLGKDLESVEELLKKHKELEEELE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1143463347 3074 EQQPEVDAACKSAKK------GARNPAAEMLSTEWKKLWLDamgLQSSLDNQKALLEEM 3126
Cdd:cd00176 157 AHEPRLKSLNELAEElleeghPDADEEIEEKLEELNERWEE---LLELAEERQKKLEEA 212
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
728-1421 |
3.36e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.20 E-value: 3.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 728 LESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKSRFGGVDKALEKLKGILE 807
Cdd:pfam15921 115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 808 ATEEL------EVDATNRAEIQEQLETTQKKADELERKIENVKK---------AALNAQNEG---LELEKKLDELIGTVN 869
Cdd:pfam15921 195 DFEEAsgkkiyEHDSMSTMHFRSLGSAISKILRELDTEISYLKGrifpvedqlEALKSESQNkieLLLQQHQDRIEQLIS 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 870 SAENELELAAPIAAESLKLADELKRAEELFQKLIEN------------EGDVSLIRAKVAEELKKKPDA--ELKKKLELL 935
Cdd:pfam15921 275 EHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNqnsmymrqlsdlESTVSQLRSELREAKRMYEDKieELEKQLVLA 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 936 YQKwpkaLGAARDRKDLVSK-AGDLvkqfGDQVQALEQRLQGDQAELDellasdkahdpevcdalklVELTMARRLADVD 1014
Cdd:pfam15921 355 NSE----LTEARTERDQFSQeSGNL----DDQLQKLLADLHKREKELS-------------------LEKEQNKRLWDRD 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1015 ALNAVMN---RIESSAPGPDANRLRRRADTLSDDAKGMAKKARTAAdlaqrkQGLAKKFERLCDEVSQFtENQKAEIQDA 1091
Cdd:pfam15921 408 TGNSITIdhlRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI------QGKNESLEKVSSLTAQL-ESTKEMLRKV 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1092 IEKDLLNAERVQSKLNKIDDFWSSNSRELKNVgdeikidatpedaQAVDTKLAELQAGIDGLLATLQeqnvHLEEKREQA 1171
Cdd:pfam15921 481 VEELTAKKMTLESSERTVSDLTASLQEKERAI-------------EATNAEITKLRSRVDLKLQELQ----HLKNEGDHL 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1172 NRVQSESQkaagkinSLVAEIADLDPIgrsRDELQKQKKEVVELAGDLGSAQTKMLELGAEWEAalgagivaqpvfEMN- 1250
Cdd:pfam15921 544 RNVQTECE-------ALKLQMAEKDKV---IEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK------------EINd 601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1251 -RAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIA--KDEALQGAPSQLLDPKQVSEKVRQLKE 1327
Cdd:pfam15921 602 rRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKqeRDQLLNEVKTSRNELNSLSEDYEVLKR 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1328 SLKPVGEKMDAFNTDCKLLIKTAGPESDTKE--LDSLLKKVGDAYSDVVG---KVSDKEMSVDAAvqqQGKVEDAYRALL 1402
Cdd:pfam15921 682 NFRNKSEEMETTTNKLKMQLKSAQSELEQTRntLKSMEGSDGHAMKVAMGmqkQITAKRGQIDAL---QSKIQFLEEAMT 758
|
730
....*....|....*....
gi 1143463347 1403 NWLEETEEMMENRKKPSAD 1421
Cdd:pfam15921 759 NANKEKHFLKEEKNKLSQE 777
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
434-901 |
8.35e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 8.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 434 LSSFIGAFDDELKGLEKVS-----IDKEKLAEQRRQTQDLVDKHSEGNAILDDVEAIAQKVtaedpsktgsaqksvgelg 508
Cdd:COG4717 44 RAMLLERLEKEADELFKPQgrkpeLNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL------------------- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 509 ARLQRQASELKARGDKINKLDSKATSFAESEAAvlgyiekqKDQLStgfPVPATKEGVKSQLLDLERMNKTGKEEQRRVD 588
Cdd:COG4717 105 EELEAELEELREELEKLEKLLQLLPLYQELEAL--------EAELA---ELPERLEELEERLEELRELEEELEELEAELA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 589 DARHSARELAREASVEKEvqdmnQREKKLLDEWEDLADQFDAVRSRANKAEQVLNEC-------------AQMEKYIGAK 655
Cdd:COG4717 174 ELQEELEELLEQLSLATE-----EELQDLAEELEELQQRLAELEEELEEAQEELEELeeeleqleneleaAALEERLKEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 656 KNMLEGIGA--------------PSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDRL 721
Cdd:COG4717 249 RLLLLIAAAllallglggsllslILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 722 NRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKE--LGELESNVEKASAMSSND---IGDQLATLDSLKSRFGGVD 796
Cdd:COG4717 329 GLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEelEQEIAALLAEAGVEDEEElraALEQAEEYQELKEELEELE 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 797 KALEKLKGILEAteelEVDATNRAEIQEQLETTQKKADELERKIENV--KKAALNAQNEGLELEKKLDELIGTVNSAENE 874
Cdd:COG4717 409 EQLEELLGELEE----LLEALDEEELEEELEELEEELEELEEELEELreELAELEAELEQLEEDGELAELLQELEELKAE 484
|
490 500
....*....|....*....|....*...
gi 1143463347 875 LELAApIAAESLKLADE-LKRAEELFQK 901
Cdd:COG4717 485 LRELA-EEWAALKLALElLEEAREEYRE 511
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
535-742 |
1.42e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 48.98 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 535 FAESEAAVLGYIEKQKDQLSTGFPvPATKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARELARE-----ASVEKEVQD 609
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDY-GDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEghpdaEEIQERLEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 610 MNQREKKLLDEWEDLADQFDavrsRANKAEQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRaQIQSMKAETEGE 689
Cdd:cd00176 84 LNQRWEELRELAEERRQRLE----EALDLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLK-KHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 690 KSALEHVNSLANELIADGG-ANVEELMKKMDRLNRKWHSLESGLDENAGRVEEA 742
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHpDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1393-1494 |
2.48e-05 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.78 E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1393 KVEDAYRALLNWLEETEEMMENrKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEasSDEEKKALGNK 1472
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLAS-EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEE--GHPDAEEIEER 78
|
90 100
....*....|....*....|..
gi 1143463347 1473 NAQIEDRYKDLLNSAVDRQRKL 1494
Cdd:smart00150 79 LEELNERWEELKELAEERRQKL 100
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2684-3061 |
5.58e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.37 E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2684 RVEKISgRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKL--KAKLEEVKEAQRDVTAkqtlf 2761
Cdd:PTZ00121 1231 KAEEAK-KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAeeKKKADEAKKAEEKKKA----- 1304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2762 DVTRKRgiglAERATRSEykQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGgafEESMNDLESWVDDELERYQKAEH 2841
Cdd:PTZ00121 1305 DEAKKK----AEEAKKAD--EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA---EAAADEAEAAEEKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2842 EPVFADIDGVRAlvdEESRRSAERKTKENGVKtvvKKADALMASGvDEKDSIAQAKERLVEKwnQVEEAARHRGNSIKEA 2921
Cdd:PTZ00121 1376 AKKKADAAKKKA---EEKKKADEAKKKAEEDK---KKADELKKAA-AAKKKADEAKKKAEEK--KKADEAKKKAEEAKKA 1446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2922 EQAAEEFDAKTHALLDWLAVEEQKlKASGLDEVEGVKQEMDEAKGRYQECLKKGEEILSKCQPAAepilrnwmRVVEARW 3001
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAK-KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK--------KADEAKK 1517
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 3002 KEVSEKVDEREFTllEQEQKAKEQNEQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQN 3061
Cdd:PTZ00121 1518 AEEAKKADEAKKA--EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1609-1820 |
1.23e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 46.28 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1609 QIQDFTLDAEDMTQFVGETEVKLGElDELPIEPDDLVEQTNILAEIAVSIADRDEMMANIFEVGKQLAIQGEPEEALIaQ 1688
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSS-TDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEI-Q 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1689 KKLDDLKFRYADLMTSADEKIALLAKAIPLSEGFHEgFDTVMQVLEDMDRDLQTIDEEDPETQAELIF----LLEEDISQ 1764
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLESVEELLkkhkELEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1143463347 1765 KmRPSVDELTALSNQLQVLCSADKADELQTNTIAMNKLVNSVADRVARRAERIEMA 1820
Cdd:cd00176 158 H-EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1457-2180 |
2.18e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1457 VAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEvtipLDSWLQSADKRLQALAKVPITVEKAE 1536
Cdd:TIGR02168 264 ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN----LERQLEELEAQLEELESKLDELAEEL 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1537 EMIGEQEA-LQDELEHKSDDLKDVLEIAPMLASLVSV--EDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDF 1613
Cdd:TIGR02168 340 AELEEKLEeLKEELESLEAELEELEAELEELESRLEEleEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1614 TLDAEDMTQFVGETEVKL--GELDELPIEPDDLVEQTNILAEIAVSIADRDEMmanifevgKQLAIQGEPEEALIAQKKL 1691
Cdd:TIGR02168 420 QQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEE--------AEQALDAAERELAQLQARL 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1692 DDLKFRYADLMTSADEKIALLAKAI-------PLSEGFH--EGFDTVMQ----------VLEDMDRDLQTIDEEDPETQA 1752
Cdd:TIGR02168 492 DSLERLQENLEGFSEGVKALLKNQSglsgilgVLSELISvdEGYEAAIEaalggrlqavVVENLNAAKKAIAFLKQNELG 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1753 ELIFLLEEDISQKmRPSVDELTALSNQLQVLCSADkadELQTNTIAMNKLVNS------VADRVARRAE-RIEMASKQSR 1825
Cdd:TIGR02168 572 RVTFLPLDSIKGT-EIQGNDREILKNIEGFLGVAK---DLVKFDPKLRKALSYllggvlVVDDLDNALElAKKLRPGYRI 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1826 AVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRITNEEASANKvqfrnvagEAKKVARQLgmegNEANEKIS 1905
Cdd:TIGR02168 648 VTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK--------ALAELRKEL----EELEEELE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1906 DTVDEGKELVEEVMALCADrtetLERALALMEQLTSQFDELNKWLDQMDAELQASpsvttatpAAELREMHDHNEELARM 1985
Cdd:TIGR02168 716 QLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEEL--------EERLEEAEEELAEAEAE 783
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1986 VAAYRPIIEGFKSDVGSLHEVLAEDQAPL--LESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQG 2063
Cdd:TIGR02168 784 IEELEAQIEQLKEELKALREALDELRAELtlLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2064 AADRLRENE----GISADPSVLESRLAENRSIVESLRDKQNAYDalkQTASELLASAPEGDAAAGDVENKLNRLE-KLWK 2138
Cdd:TIGR02168 864 LEELIEELEseleALLNERASLEEALALLRSELEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEvRIDN 940
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 1143463347 2139 EIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLE 2180
Cdd:TIGR02168 941 LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
639-740 |
7.06e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 639 EQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRAQiQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKM 718
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGKDLESVEALLKKH-EAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 1143463347 719 DRLNRKWHSLESGLDENAGRVE 740
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1828-1930 |
2.32e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 40.01 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1828 LDDLQYLIEWFSAArERILEGAPPSLDLEVLKSQLKHQRITNEEASANKVQFRNVageaKKVARQLGMEGNEANEKISDT 1907
Cdd:smart00150 4 LRDADELEAWLEEK-EQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEAL----NELGEQLIEEGHPDAEEIEER 78
|
90 100
....*....|....*....|...
gi 1143463347 1908 VDEGKELVEEVMALCADRTETLE 1930
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2065-2152 |
4.23e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 39.24 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2065 ADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDALKQTASELLASAPEgdaAAGDVENKLNRLEKLWKEIEREA 2144
Cdd:smart00150 17 KEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP---DAEEIEERLEELNERWEELKELA 93
|
....*...
gi 1143463347 2145 VDRGVLLE 2152
Cdd:smart00150 94 EERRQKLE 101
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1807-2210 |
4.82e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1807 ADRVARRAERIEMASKQSRAVLDDLQY---LIEWFSAARERiLEGAPPSLDLEVLKSQLKHQRITN--EEASANKVQFRN 1881
Cdd:PRK02224 278 AEEVRDLRERLEELEEERDDLLAEAGLddaDAEAVEARREE-LEDRDEELRDRLEECRVAAQAHNEeaESLREDADDLEE 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1882 VAGEAKKVARQLGMEGNEANEKISD---TVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNkwldQMDAELQ 1958
Cdd:PRK02224 357 RAEELREEAAELESELEEAREAVEDrreEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELR----EREAELE 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1959 aspsvttatpaAELREMHDHNEELARMVAAYRpIIEGFKSDVGSLHEVLAEDQAPLLESVAGELvqgyEEVREAVRARGH 2038
Cdd:PRK02224 433 -----------ATLRTARERVEEAEALLEAGK-CPECGQPVEGSPHVETIEEDRERVEELEAEL----EDLEEEVEEVEE 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2039 AIdnmmgatigfgERLETLVAnLQGAADRLRENEgisadpSVLESRLAENRSIVESLRDKQnayDALKQTASELLASAPE 2118
Cdd:PRK02224 497 RL-----------ERAEDLVE-AEDRIERLEERR------EDLEELIAERRETIEEKRERA---EELRERAAELEAEAEE 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2119 GDAAAGDVENKLNRLEKLWKEIEREavdRGVLLE--DVLDKAKHFWSELDSCQKAVDDLRNRLE-LVEPATGHPEQLADQ 2195
Cdd:PRK02224 556 KREAAAEAEEEAEEAREEVAELNSK---LAELKEriESLERIRTLLAAIADAEDEIERLREKREaLAELNDERRERLAEK 632
|
410
....*....|....*
gi 1143463347 2196 QEIMAQVASEMERAR 2210
Cdd:PRK02224 633 RERKRELEAEFDEAR 647
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1399-1496 |
5.89e-03 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 38.84 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1399 RALLNWLEETEEMMENRKKPSaDAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEkkALGNKNAQIED 1478
Cdd:pfam00435 11 DDLESWIEEKEALLSSEDYGK-DLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASE--EIQERLEELNE 87
|
90
....*....|....*...
gi 1143463347 1479 RYKDLLNSAVDRQRKLLD 1496
Cdd:pfam00435 88 RWEQLLELAAERKQKLEE 105
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2737-3049 |
7.12e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 7.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2737 LEKLKAKLEEVkEAQRDVTAKQtlfdvtrkrgiglAERATRseYKQISmtnEKMSKKWAEmLKKLRDRLREAEQAVLEgg 2816
Cdd:COG1196 188 LERLEDILGEL-ERQLEPLERQ-------------AEKAER--YRELK---EELKELEAE-LLLLKLRELEAELEELE-- 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2817 afeESMNDLESWVDDELERYQKAEhepvfADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQA 2896
Cdd:COG1196 246 ---AELEELEAELEELEAELAELE-----AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2897 KERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASgLDEVEGVKQEMDEAKGRYQECLKKGE 2976
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-EAELAEAEEELEELAEELLEALRAAA 396
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1143463347 2977 EILSKCQPAAEPILRNwmrvvEARWKEVSEKVDEREFTLLEQEQKAKEQNEQIEKLAKFAAQKREELNRMIEQ 3049
Cdd:COG1196 397 ELAAQLEELEEAEEAL-----LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| GAS2 |
smart00243 |
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain |
3227-3299 |
1.94e-43 |
|
Growth-Arrest-Specific Protein 2 Domain; GROWTH-ARREST-SPECIFIC PROTEIN 2 Domain
Pssm-ID: 128539 Cd Length: 73 Bit Score: 153.37 E-value: 1.94e-43
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1143463347 3227 EKITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCRAKG 3299
Cdd:smart00243 1 DKIDDEVKRIVEDCKCPTKFQVEKISEGKYRFGDSQILRLVRILRSTVMVRVGGGWETLDEYLLKHDPCRAKG 73
|
|
| GAS2 |
pfam02187 |
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members ... |
3229-3297 |
1.64e-33 |
|
Growth-Arrest-Specific Protein 2 Domain; The GAR2 domain is common in plakin family members and Gas2 family members. The GAR domain comprises around 57 amino acids and has been shown to bind to microtubules.
Pssm-ID: 460480 Cd Length: 69 Bit Score: 124.63 E-value: 1.64e-33
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1143463347 3229 ITHEIELQKKTCSCCTPYQIEKISENHYRFGDTHIKRMVRILRSTVMVRVGGGWESLDEFLHKHDPCRA 3297
Cdd:pfam02187 1 LDDEVRRIVAQCTCPTKFPVEKVGEGKYRFGDSQKLVFVRILRSHVMVRVGGGWDTLEEYLLKHDPCRA 69
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2270-2475 |
4.01e-18 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 85.96 E-value: 4.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHlAATVRQP 2349
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSST---DYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLENLMLQMGKLAStIAQLTAWMDKTRATLKDIAPPKnavNLRDIEIAQCKLVVLSNDIH 2429
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGK---DLESVEELLKKHKELEEELE 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1143463347 2430 AHQDSVNAVNRAAQKYIQTSG-ALDAETSDSLKSMNLKWEDIQKVLE 2475
Cdd:cd00176 157 AHEPRLKSLNELAEELLEEGHpDADEEIEEKLEELNERWEELLELAE 203
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2494-2699 |
2.92e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 83.26 E-value: 2.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2494 EVEKWQRWLEETESALLSTKPtGGLPETAEFQLDEFKALKLDVEHNASPLEAhLHATEQHLKEEPQDADTWLSKTHGAMK 2573
Cdd:cd00176 8 DADELEAWLSEKEELLSSTDY-GDDLESVEALLKKHEALEAELAAHEERVEA-LNELGEQLIEEGHPDAEEIQERLEELN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2574 TKWNKVKELLVDREKKLQVAYEQAVALESALnDMEDWIIAAERKLTDQPSISRLPDViEKQLAEHESWMEEVAGRKMAMT 2653
Cdd:cd00176 86 QRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKEAALASEDLGKDLESV-EELLKKHKELEEELEAHEPRLK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1143463347 2654 KHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQL 2699
Cdd:cd00176 164 SLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKL 209
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2818-3017 |
4.45e-17 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 82.88 E-value: 4.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2818 FEESMNDLESWVDDELERYQKAEHEpvfADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAK 2897
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYG---DDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQERL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2898 ERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDaKTHALLDWLAVEEQKLKASG-----------LDEVEGVKQEMDEAKG 2966
Cdd:cd00176 82 EELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDlgkdlesveelLKKHKELEEELEAHEP 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 2967 RYQECLKKGEEILSKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLE 3017
Cdd:cd00176 161 RLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEE 211
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1390-1607 |
1.62e-15 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 78.26 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1390 QQGKVEDAYRALLNWLEETEEMMeNRKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKkaL 1469
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELL-SSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEE--I 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1470 GNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIpLDSWLQSADKRLQALAKVPiTVEKAEEMIGEQEALQDEL 1549
Cdd:cd00176 78 QERLEELNQRWEELRELAEERRQRLEEALDLQQFFRDADD-LEQWLEEKEAALASEDLGK-DLESVEELLKKHKELEEEL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1143463347 1550 EHKSDDLKDVLEIAPMLASLVSVEDANSISGQVNQLEARARALDAGITNMRPLLESFL 1607
Cdd:cd00176 156 EAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
711-1431 |
5.17e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.95 E-value: 5.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 711 VEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKS 790
Cdd:TIGR02168 248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 791 RFGGVDKALEKLKgilEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNS 870
Cdd:TIGR02168 328 LESKLDELAEELA---ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 871 AENELElaaPIAAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEELKKKPDAELKKKLELLYQKWPKALGAARDRK 950
Cdd:TIGR02168 405 LEARLE---RLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 951 DLVSKAGDLVkqfgDQVQALEQRLQGDQAELDELLASDK---AHDPEVCDALKL-------VELTMARRLAD--VDALNA 1018
Cdd:TIGR02168 482 RELAQLQARL----DSLERLQENLEGFSEGVKALLKNQSglsGILGVLSELISVdegyeaaIEAALGGRLQAvvVENLNA 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1019 VMNRIESSAPgpdaNRLRRRADTLSDDAKGMAKKARTAADLAQrkqglAKKFERLCDEVSQFTENQKAEIQD-----AIE 1093
Cdd:TIGR02168 558 AKKAIAFLKQ----NELGRVTFLPLDSIKGTEIQGNDREILKN-----IEGFLGVAKDLVKFDPKLRKALSYllggvLVV 628
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1094 KDLLNAERVQSKLNKI-------DDFWS-----------------SNSRELKNVGDEI-----KIDATPEDAQAVDTKLA 1144
Cdd:TIGR02168 629 DDLDNALELAKKLRPGyrivtldGDLVRpggvitggsaktnssilERRREIEELEEKIeeleeKIAELEKALAELRKELE 708
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1145 ELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKINSLVAEIADLDPIGRS-RDELQKQKKEVVELAGDLGSAQ 1223
Cdd:TIGR02168 709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEElEERLEEAEEELAEAEAEIEELE 788
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1224 TKMLELGAEWEaALGAGIVAQpvfemnRAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIAKD- 1302
Cdd:TIGR02168 789 AQIEQLKEELK-ALREALDEL------RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEi 861
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1303 EALQGAPSQLLDP-KQVSEKVRQLKESLKPVGEKMDAFNTDckllIKTAgpESDTKELDSLLKKVGDAYSDVVGKVSDKE 1381
Cdd:TIGR02168 862 EELEELIEELESElEALLNERASLEEALALLRSELEELSEE----LREL--ESKRSELRRELEELREKLAQLELRLEGLE 935
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1382 MSVDaavQQQGKVEDAYRALLnwleetEEMMENRKKPSADAKVAKAQLHD 1431
Cdd:TIGR02168 936 VRID---NLQERLSEEYSLTL------EEAEALENKIEDDEEEARRRLKR 976
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1823-2044 |
3.22e-13 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 71.71 E-value: 3.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1823 QSRAVLDDLQYLIEWFSAArERILEGAPPSLDLEVLKSQLKHQRITNEEASANKVQFRNVAGEAKKVARqlgmEGNEANE 1902
Cdd:cd00176 1 KLQQFLRDADELEAWLSEK-EELLSSTDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIE----EGHPDAE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1903 KISDTVDEGKELVEEVMALCADRTETLERALALMEQLtSQFDELNKWLDQMDAELQASPSVTTATpaaELREMHDHNEEL 1982
Cdd:cd00176 76 EIQERLEELNQRWEELRELAEERRQRLEEALDLQQFF-RDADDLEQWLEEKEAALASEDLGKDLE---SVEELLKKHKEL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1143463347 1983 ARMVAAYRPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQGYEEVREAVRARGHAIDNMM 2044
Cdd:cd00176 152 EEELEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
711-1285 |
4.42e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 4.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 711 VEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASA---MSSNDIGDQLATLDS 787
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyELLAELARLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 788 LKSRFGGVDKALEKLKG-ILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIG 866
Cdd:COG1196 307 LEERRRELEERLEELEEeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 867 TVNSAENE-LELAAPIAAESLKLADELKRAEELFQKLIENEGDvsLIRAKVAEELKKKPDAELKKKLELLYQKwpkALGA 945
Cdd:COG1196 387 ELLEALRAaAELAAQLEELEEAEEALLERLERLEEELEELEEA--LAELEEEEEEEEEALEEAAEEEAELEEE---EEAL 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 946 ARDRKDLVSKAgdlvKQFGDQVQALEQRLQGDQAELDELLASDKAHDPEVCDALKLVELTMARRLA-DVDALNAVMNRIE 1024
Cdd:COG1196 462 LELLAELLEEA----ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgAVAVLIGVEAAYE 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1025 SSAPGPDANRLRRRADTLSDDAkgmakkARTAADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDAIEKDLLNAERVQS 1104
Cdd:COG1196 538 AALEAALAAALQNIVVEDDEVA------AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1105 KLNKIDDFWSSNSRELKNVGDEIKIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGK 1184
Cdd:COG1196 612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1185 INSLVAEIADLDPIGRSRDELQKQKKEVVELAGDLGSAQTKMLELGAEWEaalgagivaqpvfEMNRAATDELNKLAARA 1264
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL-------------LEEEELLEEEALEELPE 758
|
570 580
....*....|....*....|.
gi 1143463347 1265 GKRLAQREKKITETEDEIDKL 1285
Cdd:COG1196 759 PPDLEELERELERLEREIEAL 779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
24-874 |
6.51e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.56 E-value: 6.51e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 24 RIDEARFEAKSLMDEV-------IREESRLKtigaSVLKIEQEISAMRDDVRASgstddvgiSVDEVYETRRRVEDDYMQ 96
Cdd:PTZ00121 1088 RADEATEEAFGKAEEAkktetgkAEEARKAE----EAKKKAEDARKAEEARKAE--------DARKAEEARKAEDAKRVE 1155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 97 LLRQCQDLISFQNRLHAMNDEHSEQARRADEWLQMLQ-NDVEDVDQDPRFQRDEDrIQRIEELNRMA-AGGSSQLDDAEQ 174
Cdd:PTZ00121 1156 IARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEElRKAEDARKAEAARKAEE-ERKAEEARKAEdAKKAEAVKKAEE 1234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 175 ASRRLLTALEGTNVANDVRARHEELANLRRGKHQKVIDRlsqnmmeaASRKAEAEGVKQAVENLRQWSEQTAQRTRQPVQ 254
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIK--------AEEARKADELKKAEEKKKADEAKKAEEKKKADE 1306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 255 LpltELDLHEARKDEQvLHGEIENRLALIEELEKKAADVGDHASLAELQECKMKLKRSNSDLKGLRDnifdainglQTVN 334
Cdd:PTZ00121 1307 A---KKKAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAA---------EKKK 1373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 335 SEGETLSRAVDSAGAKIRSARlpEAQSEVEALQDQADNLERITNNLCNIPNVTRTEPVIQKSKDLRKRVDSCAQELDARm 414
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKAD--EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK- 1450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 415 gKLAElESLDAEfdGAKNKLSSFIGAFDDELKGLEKVSIDK-EKLAEQRRQTQDLVDKHSEGNAILDDVEAIAQKVTAED 493
Cdd:PTZ00121 1451 -KKAE-EAKKAE--EAKKKAEEAKKADEAKKKAEEAKKADEaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 494 PSKTGSAQKSVGELGARLQRQASELKaRGDKINKLDSKATSFAESEAAVLGYIEKQKDQLSTgfpvPATKEGVKSQLLDL 573
Cdd:PTZ00121 1527 AKKAEEAKKADEAKKAEEKKKADELK-KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK----KAEEARIEEVMKLY 1601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 574 ERMNKTGKEEQRRVDDARHSARELAREASVEKEVQDMNQREKKlldewedladqfdavrsRANKAEQVLNEcaqmEKYIG 653
Cdd:PTZ00121 1602 EEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE-----------------EKKKAEELKKA----EEENK 1660
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 654 AKKnmlegigapSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLANEliadgGANVEELMKKMDRLNRKWHSLESGLD 733
Cdd:PTZ00121 1661 IKA---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEE-----AKKAEELKKKEAEEKKKAEELKKAEE 1726
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 734 ENAGRVEEAAKLGQELKDIQKELRKELGElesnvekasamssndigdqlatLDSLKSRFGGVDKALEKLKGILEATEELE 813
Cdd:PTZ00121 1727 ENKIKAEEAKKEAEEDKKKAEEAKKDEEE----------------------KKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 814 VDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENE 874
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2380-2594 |
2.06e-12 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 69.01 E-value: 2.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2380 KLASTIAQLTAWMDKTRATLKDIAPPKNavnLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTSGALDAETSDS 2459
Cdd:cd00176 4 QFLRDADELEAWLSEKEELLSSTDYGDD---LESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2460 LKSMNLKWEDIQKVLESLAFDMEVAKKEAENVGgEVEKWQRWLEETESALLSTKPtGGLPETAEFQLDEFKALKLDVEHN 2539
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALASEDL-GKDLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 2540 ASPLEAHLHATEQHLKEEPQDADTWLSKTHGAMKTKWNKVKELLVDREKKLQVAY 2594
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
399-1128 |
5.48e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 5.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 399 LRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGL-EKVSIDKEKLAEQRRQTQDLVDKHSEGNA 477
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaNEISRLEQQKQILRERLANLERQLEELEA 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 478 ILDDVEA---IAQKVTAEDPSKTGSAQKSVGELGARLQRQASELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQLS 554
Cdd:TIGR02168 324 QLEELESkldELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 555 TgfpvpatkegVKSQLLDLERMNKTGKEEQRRVDDARHSARELAREASVEKEvqdmNQREKKLLDEWEDLADQFDAVRSR 634
Cdd:TIGR02168 404 R----------LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEEL----EEELEELQEELERLEEALEELREE 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 635 ANKAEQVLNECAQMEKYIGAKKNMLE------------------------GIGAP-----STEPG----VAKANRAQIQS 681
Cdd:TIGR02168 470 LEEAEQALDAAERELAQLQARLDSLErlqenlegfsegvkallknqsglsGILGVlseliSVDEGyeaaIEAALGGRLQA 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 682 mkAETEGEKSALEHVNSLANEliADGGANVEELMKKMDRLnrkwhsLESGLDENAGRVEEAAKLGQELKDIQKELRKELG 761
Cdd:TIGR02168 550 --VVVENLNAAKKAIAFLKQN--ELGRVTFLPLDSIKGTE------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 762 ELESNV----EKASAM---SSNDIGDQLATLDSLKSRFGGV--DKALEKLKGILEATEELEVDATNRAEIQEQLETTQKK 832
Cdd:TIGR02168 620 YLLGGVlvvdDLDNALelaKKLRPGYRIVTLDGDLVRPGGVitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 833 ADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELE-LAAPIAAESLKLADELKRAEELFQKLIENEGdvsl 911
Cdd:TIGR02168 700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEELEERLEEAEE---- 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 912 iRAKVAEELKKKPDAELKKKLELLyQKWPKALGAARDRKDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDELLASDKAH 991
Cdd:TIGR02168 776 -ELAEAEAEIEELEAQIEQLKEEL-KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 992 DPEVCDALKLVELTMARRLADVDALNAVMNRIESsapgpDANRLRRRADTLSDDAKGMAKKARTAADLAQRKQGLAKKFE 1071
Cdd:TIGR02168 854 IESLAAEIEELEELIEELESELEALLNERASLEE-----ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 1143463347 1072 RLCDEvsqfTENQKAEIQDAI-EKDLLNAERVQSKLNKIDDFWSSNSRELKNVGDEIK 1128
Cdd:TIGR02168 929 LRLEG----LEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
562-1327 |
7.43e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.10 E-value: 7.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 562 TKEGVKSQLLDLERMNKTGKE------EQRRVDDARHSARELAREASVEKEVQDMNQREKKLLDEWEDLADQFDAVR--S 633
Cdd:PTZ00121 1058 GKAEAKAHVGQDEGLKPSYKDfdfdakEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARkaE 1137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 634 RANKAEQVLNecAQMEKYIGAKKNMLEG----IGAPSTEPGVAKANRAQIQSMKAEtegEKSALEHVNSLANELIADGGA 709
Cdd:PTZ00121 1138 DARKAEEARK--AEDAKRVEIARKAEDArkaeEARKAEDAKKAEAARKAEEVRKAE---ELRKAEDARKAEAARKAEEER 1212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 710 NVEELMKKMDRlnRKWHSLESGldENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLK 789
Cdd:PTZ00121 1213 KAEEARKAEDA--KKAEAVKKA--EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEE 1288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 790 SRFGGVDKALEKLKGILEATEELEvDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVN 869
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAE-EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAE 1367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 870 SAENELELAAPIAAESLKLADELKRAEELFQKLIENEgdvsliraKVAEELKKKpdAELKKKLEllyqkwpkalgAARDR 949
Cdd:PTZ00121 1368 AAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK--------KKADELKKA--AAAKKKAD-----------EAKKK 1426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 950 KDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDELLASdKAHDPEVCDALKlveltmaRRLADVDALNAVMNRIESSAPG 1029
Cdd:PTZ00121 1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK-KAEEAKKADEAK-------KKAEEAKKADEAKKKAEEAKKK 1498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1030 PDANRLRRRADTLSDDAKgMAKKARTAADLAQ----RKQGLAKKFE--RLCDEVSQFTENQKAEIQDAIEKDLLNAERVQ 1103
Cdd:PTZ00121 1499 ADEAKKAAEAKKKADEAK-KAEEAKKADEAKKaeeaKKADEAKKAEekKKADELKKAEELKKAEEKKKAEEAKKAEEDKN 1577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1104 SKLNKIDDFWSSNSRELKNVGDEIKIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAG 1183
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1184 KINSLVAEIAdldpigrSRDELQKQKKEvvELAGDLGSAQTKMLELGAEWEAALGAGIVAQPVFEMNRAA-----TDELN 1258
Cdd:PTZ00121 1658 ENKIKAAEEA-------KKAEEDKKKAE--EAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAeelkkAEEEN 1728
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 1259 KLAARAGKRLAQREKKITET----EDEIDKL-HADADQIVGALEAIAKDEALQGAPSQLLDPKQVSEKVRQLKE 1327
Cdd:PTZ00121 1729 KIKAEEAKKEAEEDKKKAEEakkdEEEKKKIaHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2050-2264 |
1.25e-11 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 66.70 E-value: 1.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2050 FGERLETLVANLQGAADRLRENEGISaDPSVLESRLAENRSIVESLRDKQNAYDALKQTASELLASAPEgdaAAGDVENK 2129
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDYGD-DLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHP---DAEEIQER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2130 LNRLEKLWKEIEREAVDRGVLLEDVLDKAKHFWsELDSCQKAVDDLRNRLElVEPATGHPEQLADQQEIMAQVASEMERA 2209
Cdd:cd00176 81 LEELNQRWEELRELAEERRQRLEEALDLQQFFR-DADDLEQWLEEKEAALA-SEDLGKDLESVEELLKKHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 2210 RPRIEALSIAGKQLADYVPDDEKAVIENQVANVRGGFSTITGLFAEKKRDLIAAM 2264
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2270-2372 |
2.31e-11 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 62.73 E-value: 2.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHlAATVRQP 2349
Cdd:smart00150 3 FLRDADELEAWLEEKEQLLASE---DLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPD-AEEIEER 78
|
90 100
....*....|....*....|...
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLE 2372
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
207-875 |
2.58e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 70.15 E-value: 2.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 207 HQKVIDRLSQNMMEAASRKAEAEGVKQAVENLRQWSEQTAQRTRQPVQLPLTELDLHEARKD------------------ 268
Cdd:pfam15921 101 HEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmledsntqieqlrkmml 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 269 --EQVLHgeiENRLALIEELEKKAADVGDHASLAELQECKMK------LKRSNSDLKGLRDNIFDAINGLQTVNSEGETL 340
Cdd:pfam15921 181 shEGVLQ---EIRSILVDFEEASGKKIYEHDSMSTMHFRSLGsaiskiLRELDTEISYLKGRIFPVEDQLEALKSESQNK 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 341 -----------------SRAVDSAG--AKIRSAR--LPEAQSEVEALQDQADNLERITnnLCNIPNVTRTepVIQKSKDL 399
Cdd:pfam15921 258 ielllqqhqdrieqlisEHEVEITGltEKASSARsqANSIQSQLEIIQEQARNQNSMY--MRQLSDLEST--VSQLRSEL 333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 400 RKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGLEKVSIDKEK-LAEQRRQTQDLVDKHSeGNAI 478
Cdd:pfam15921 334 REAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKeLSLEKEQNKRLWDRDT-GNSI 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 479 --------LDDVEAIAQKVTAedpskTGSAQKSvgELGARLQRQASELKARGDKINKLdSKATSFAESeaavlgyiekqk 550
Cdd:pfam15921 413 tidhlrreLDDRNMEVQRLEA-----LLKAMKS--ECQGQMERQMAAIQGKNESLEKV-SSLTAQLES------------ 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 551 dqlstgfpvpaTKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARELARE-ASVEKEVQDMNQREKKLLDEWEDLADQFD 629
Cdd:pfam15921 473 -----------TKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAiEATNAEITKLRSRVDLKLQELQHLKNEGD 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 630 AVRSRANKAEQVLNECAQMEKYIGAKK----NMLEGIGAPSTEPGVAKANRAQIQSmkaETEGEKSALEHVNSLANElia 705
Cdd:pfam15921 542 HLRNVQTECEALKLQMAEKDKVIEILRqqieNMTQLVGQHGRTAGAMQVEKAQLEK---EINDRRLELQEFKILKDK--- 615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 706 dGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATL 785
Cdd:pfam15921 616 -KDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTT 694
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 786 DSLKSRFGGVDKALEKLKGILEATEELEVDATNRA-EIQEQLETTQKKADELERKIENVKKAALNAQNEG--LELEK-KL 861
Cdd:pfam15921 695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKhfLKEEKnKL 774
|
730
....*....|....
gi 1143463347 862 DELIGTVNSAENEL 875
Cdd:pfam15921 775 SQELSTVATEKNKM 788
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
637-850 |
3.95e-11 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 65.54 E-value: 3.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 637 KAEQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVaKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMK 716
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLESV-EALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 717 KMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQkELRKELGELEsnvekaSAMSSNDIGDQLATLDSLKSRFGGVD 796
Cdd:cd00176 80 RLEELNQRWEELRELAEERRQRLEEALDLQQFFRDAD-DLEQWLEEKE------AALASEDLGKDLESVEELLKKHKELE 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 797 KALEKLKGILEATEEL------EVDATNRAEIQEQLETTQKKADELERKIENVKKAALNA 850
Cdd:cd00176 153 EELEAHEPRLKSLNELaeelleEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2187-2375 |
4.34e-11 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 65.16 E-value: 4.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2187 GHPEQLADQQEIMAQVASEMERARPRIEALSIAGKQLADYVPDDeKAVIENQVANVRGGFSTITGLFAEKKRDLIAAMEe 2266
Cdd:cd00176 30 DDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPD-AEEIQERLEELNQRWEELRELAEERRQRLEEALD- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2267 AMTFHGDLQELLKWLDMAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAADAPPHLAATV 2346
Cdd:cd00176 108 LQQFFRDADDLEQWLEEKEAALASE---DLGKDLESVEELLKKHKELEEELEAHEPRLKSLNELAEELLEEGHPDADEEI 184
|
170 180
....*....|....*....|....*....
gi 1143463347 2347 RQPVADLNTRWSRLNAALAEREHKLENLM 2375
Cdd:cd00176 185 EEKLEELNERWEELLELAEERQKKLEEAL 213
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
749-1550 |
4.46e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.23 E-value: 4.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 749 LKDIQKELRKELGELESNVEKASAMSsnDIGDQL--ATLDSLKSRFGGVDKALEKLKGILEATEELEVDATNR-AEIQEQ 825
Cdd:TIGR02168 191 LEDILNELERQLKSLERQAEKAERYK--ELKAELreLELALLVLRLEELREELEELQEELKEAEEELEELTAElQELEEK 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 826 LETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELELAAPIAAESLKLADELK-RAEELFQKLIE 904
Cdd:TIGR02168 269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAeELAELEEKLEE 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 905 NEGDVSLIRAKVAEELKKKPdaELKKKLELLYQKWpkaLGAARDRKDLVSKAGDLVKQF---GDQVQALEQRLQGDQAEL 981
Cdd:TIGR02168 349 LKEELESLEAELEELEAELE--ELESRLEELEEQL---ETLRSKVAQLELQIASLNNEIerlEARLERLEDRRERLQQEI 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 982 DELLASDKAHDPEVCDA-----------LKLVELTMARRLADVDALNAVMNRIESSAPGpDANRLRRRADTLSDDAKGMA 1050
Cdd:TIGR02168 424 EELLKKLEEAELKELQAeleeleeeleeLQEELERLEEALEELREELEEAEQALDAAER-ELAQLQARLDSLERLQENLE 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1051 KKARTAADLAQRKQGLAKKFERLCDEVSqFTENQKAEIQDAIEKDLLNAerVQSKLNKIDDFWSSNSRelKNVGDEIKID 1130
Cdd:TIGR02168 503 GFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGGRLQAV--VVENLNAAKKAIAFLKQ--NELGRVTFLP 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1131 ATPEDAQAVDTKLAELQAGIDGLLATLQEqnvhLEEKREQAnrvqsesQKAAGKINSLVAEIADLDpigrSRDELQKQKK 1210
Cdd:TIGR02168 578 LDSIKGTEIQGNDREILKNIEGFLGVAKD----LVKFDPKL-------RKALSYLLGGVLVVDDLD----NALELAKKLR 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1211 E---VVELAGDLgsaqtkmleLGAEWEAALGAGIVAQPVFEmNRAATDELNKLAARAGKRLAQREKKITETEDEIDKLHA 1287
Cdd:TIGR02168 643 PgyrIVTLDGDL---------VRPGGVITGGSAKTNSSILE-RRREIEELEEKIEELEEKIAELEKALAELRKELEELEE 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1288 DADQIVGALEAIAKDEALQGAPSQLLDPK--QVSEKVRQLKESLKPVGEKMDAFNTDC-KLLIKTAGPESDTKELDSLLK 1364
Cdd:TIGR02168 713 ELEQLRKELEELSRQISALRKDLARLEAEveQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIE 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1365 KVGDAYSDVVGKVSDKEMSV----DAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVAKAQLHDYEVLMKHVE 1440
Cdd:TIGR02168 793 QLKEELKALREALDELRAELtllnEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1441 DKKPSVDGFKAMIEKIVAEASSDEEKkaLGNKNAQIEDRYKDLLNSAVDRQRKLldaVDLAERLQEVTIPLDSWLQSADK 1520
Cdd:TIGR02168 873 SELEALLNERASLEEALALLRSELEE--LSEELRELESKRSELRRELEELREKL---AQLELRLEGLEVRIDNLQERLSE 947
|
810 820 830
....*....|....*....|....*....|
gi 1143463347 1521 RLQALAKVPITVEKAEEMigEQEALQDELE 1550
Cdd:TIGR02168 948 EYSLTLEEAEALENKIED--DEEEARRRLK 975
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
672-1198 |
4.99e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.73 E-value: 4.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 672 AKANRAQIQSMKAETEGEKSALEHVNSLANELIAD---GGANVEELMKKMDRLNRKWHSLESGLDENAGRVEE----AAK 744
Cdd:COG1196 255 LEELEAELAELEAELEELRLELEELELELEEAQAEeyeLLAELARLEQDIARLEERRRELEERLEELEEELAEleeeLEE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 745 LGQELKDIQKELRKELGELES------NVEKASAMSSNDIGDQLATLDSLKSR-FGGVDKALEKLKGILEATEELEVDAT 817
Cdd:COG1196 335 LEEELEELEEELEEAEEELEEaeaelaEAEEALLEAEAELAEAEEELEELAEElLEALRAAAELAAQLEELEEAEEALLE 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 818 NRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELELAAPIAAESLKLADELKRAEE 897
Cdd:COG1196 415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 898 LFQKLIENEGDvsliRAKVAEELKKKPDAELKKKLELLYQKWPKALGAARDRKDLVSKAGDLVKQFGD---QVQALEQRL 974
Cdd:COG1196 495 LLLEAEADYEG----FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVaaaAIEYLKAAK 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 975 QGDQAELDELLASDKAHDPEVCDALKLVELTMARRLADVDALNAVMNRIESSAPGPDANRLRRRADTLSDDAKGMAKKAR 1054
Cdd:COG1196 571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1055 TAADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDAIEKDLLNAERVQSKLNKIDDfwSSNSRELKNVGDEIKIDATPE 1134
Cdd:COG1196 651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER--ELAEAEEERLEEELEEEALEE 728
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 1135 DAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRvqsesqkaagKINSLVAEIADLDPI 1198
Cdd:COG1196 729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER----------ELERLEREIEALGPV 782
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
238-984 |
2.00e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 238 LRQWSEQTAQRTRQPVQLPLTELDLHEARKDEQVLHGEIENRLALIEELEKKAADVGD--HASLAELQECKMKLKRSNSD 315
Cdd:TIGR02168 231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKelYALANEISRLEQQKQILRER 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 316 LKGLRDNIFDAINGLQTVNSEGETLSRAVDSAGAKIRsarlpEAQSEVEALQDQADNLERITNNLcnipnVTRTEPVIQK 395
Cdd:TIGR02168 311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----ELKEELESLEAELEELEAELEEL-----ESRLEELEEQ 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 396 SKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGLEKVSIdKEKLAEQRRQTQDLVDKHSEG 475
Cdd:TIGR02168 381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL-QAELEELEEELEELQEELERL 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 476 NAILDDV-EAIAQKVTAEDPsktgsaqksvgelgarLQRQASELKARGDKINKLDSKATSFAESEAAVLgyieKQKDQLS 554
Cdd:TIGR02168 460 EEALEELrEELEEAEQALDA----------------AERELAQLQARLDSLERLQENLEGFSEGVKALL----KNQSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 555 TGFpvpatkeGVKSQLLDLERMNKTGKEEqrrVDDARHSARELAREASVEKEVQDMNQREKK-----LLDEWEDLADQFD 629
Cdd:TIGR02168 520 GIL-------GVLSELISVDEGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAFLKQNELGrvtflPLDSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 630 AVRSRANKaEQVLNECAQMEKYIGAKKNMLEGIGApstepGVAKANR-AQIQSMKAETEGEKSALehvnSLANELIADGG 708
Cdd:TIGR02168 590 DREILKNI-EGFLGVAKDLVKFDPKLRKALSYLLG-----GVLVVDDlDNALELAKKLRPGYRIV----TLDGDLVRPGG 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 709 A-NVEELMKKMDRLNRKwhsleSGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAM---SSNDIGDQLAT 784
Cdd:TIGR02168 660 ViTGGSAKTNSSILERR-----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEleeLSRQISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 785 LDSLKSRFGGVDKALEKLKG-ILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDE 863
Cdd:TIGR02168 735 LARLEAEVEQLEERIAQLSKeLTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL 814
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 864 LIGTVNSAENELElaapiaAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEElkKKPDAELKKKLELLYQKWPKAL 943
Cdd:TIGR02168 815 LNEEAANLRERLE------SLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL--EELIEELESELEALLNERASLE 886
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 1143463347 944 GAARDRKDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDEL 984
Cdd:TIGR02168 887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2466-3049 |
2.52e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 63.62 E-value: 2.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2466 KWEDIQKVlESLAFDMEVAKKEAENVGGEVEKWQRWLEETESALLSTKPTGGLPETAE--FQLDEF-KALKLDVEHNASP 2542
Cdd:PTZ00121 1219 KAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEeaRKADELkKAEEKKKADEAKK 1297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2543 LEAHLHATEQHLKEEPQDADTWLSKTHGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTDQp 2622
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEA- 1376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2623 siSRLPDVIEKQlAEHESWMEEvAGRKMAMTKHQASGVHmQYYCEKKDAIPIKNRLVSLKHRVE-KISGRTAERAKQLAV 2701
Cdd:PTZ00121 1377 --KKKADAAKKK-AEEKKKADE-AKKKAEEDKKKADELK-KAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAKK 1451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2702 TRDEVATWQDGLHDLEHF-ISDVLVKIAPEPNTTsslEKLKAKLEEVK----EAQRDVTAKQTLFDVTRKRGIGLAERAT 2776
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAkKADEAKKKAEEAKKA---DEAKKKAEEAKkkadEAKKAAEAKKKADEAKKAEEAKKADEAK 1528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2777 RSEYKQISMTNEKMS-KKWAEMLKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALV 2855
Cdd:PTZ00121 1529 KAEEAKKADEAKKAEeKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2856 DEESRRSAERKTKENGVKtvvkKADalmasgvDEKDSIAQAKERLVEKWNQVEEAAR-HRGNSIKEAEQAAEEFDAKTHA 2934
Cdd:PTZ00121 1609 AEEAKKAEEAKIKAEELK----KAE-------EEKKKVEQLKKKEAEEKKKAEELKKaEEENKIKAAEEAKKAEEDKKKA 1677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2935 LLDWLAVEEQKLKASGLDEVEGVKQEMDEAKGRYQECLKKGEEIlskcQPAAEpilRNWMRVVEARWKEVSEKVDEREFT 3014
Cdd:PTZ00121 1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEEL----KKAEE---ENKIKAEEAKKEAEEDKKKAEEAK 1750
|
570 580 590
....*....|....*....|....*....|....*
gi 1143463347 3015 LLEQEQKAKEQNEQIEKlaKFAAQKREELNRMIEQ 3049
Cdd:PTZ00121 1751 KDEEEKKKIAHLKKEEE--KKAEEIRKEKEAVIEE 1783
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
713-1330 |
3.35e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.16 E-value: 3.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 713 ELMKKMDRLnRKWHSLESGLDENAGRVEEaaKLGQELKDIqKELRKELGELESNVEKASAmssndigdQLATLDSLKSRF 792
Cdd:PRK03918 173 EIKRRIERL-EKFIKRTENIEELIKEKEK--ELEEVLREI-NEISSELPELREELEKLEK--------EVKELEELKEEI 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 793 GGVDKALEKLKGILEATEELEVdatnraEIQEQLETTQKKADELERKIENVKKAALNAQnEGLELEKKLDELIGTVNSAE 872
Cdd:PRK03918 241 EELEKELESLEGSKRKLEEKIR------ELEERIEELKKEIEELEEKVKELKELKEKAE-EYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 873 NELElaapiaaeslKLADELKRAEELFQKLIENEGDVslirakvaEELKKKpDAELKKKLELLyQKWPKALgaardrkdl 952
Cdd:PRK03918 314 KRLS----------RLEEEINGIEERIKELEEKEERL--------EELKKK-LKELEKRLEEL-EERHELY--------- 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 953 vskagDLVKQFGDQVQALEQRLQGDQAE-LDELLASDKAHDPEVCDALKLVELTMARRLADVDALNAVMNRIESsAPG-- 1029
Cdd:PRK03918 365 -----EEAKAKKEELERLKKRLTGLTPEkLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK-AKGkc 438
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1030 PDANRLrrradtLSDDAKG--MAKKARTAADLAQRKQGLAKKFERLcdevsqftENQKAEIQDAIEKdllnaERVQSKLN 1107
Cdd:PRK03918 439 PVCGRE------LTEEHRKelLEEYTAELKRIEKELKEIEEKERKL--------RKELRELEKVLKK-----ESELIKLK 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1108 KIDDFWSSNSRELKNVGDEiKIDATPEDAQAVDTKLAELQAGIDGL-------------LATLQEQNVHLEEKREQANRV 1174
Cdd:PRK03918 500 ELAEQLKELEEKLKKYNLE-ELEKKAEEYEKLKEKLIKLKGEIKSLkkelekleelkkkLAELEKKLDELEEELAELLKE 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1175 QSEsqKAAGKINSLVAEIADLDPIGRSRDELQKQKKEVVELAGDLGSAQTKMLELGAEWEAALGA------------GIV 1242
Cdd:PRK03918 579 LEE--LGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRleelrkeleeleKKY 656
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1243 AQPVFEMNRAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIAKDEalqgapSQLLDPKQVSEKV 1322
Cdd:PRK03918 657 SEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLE------KALERVEELREKV 730
|
....*...
gi 1143463347 1323 RQLKESLK 1330
Cdd:PRK03918 731 KKYKALLK 738
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
77-864 |
5.88e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.38 E-value: 5.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 77 GISVDEVYETRRRVEDDYMQLLRQCQDLISFQNRLHA----MNDEHSEQARRADEW---LQMLQNDVEDVDQDPRFQRde 149
Cdd:TIGR02168 231 VLRLEELREELEELQEELKEAEEELEELTAELQELEEkleeLRLEVSELEEEIEELqkeLYALANEISRLEQQKQILR-- 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 150 driQRIEELNRMAAGGSSQLDDAEQASRRLLtalegtnvandvrarhEELANLrrgkhQKVIDRLSQNMMEAASRKAEAE 229
Cdd:TIGR02168 309 ---ERLANLERQLEELEAQLEELESKLDELA----------------EELAEL-----EEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 230 GVKQAVENLRQWSEQTAQRTRQpvqlpltelDLHEARKDEQVLHGEIENRLALIEELEKKAADVGDHASLAELQECKMKL 309
Cdd:TIGR02168 365 AELEELESRLEELEEQLETLRS---------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 310 KRSNSDLKGLRDNIFDAINGLQTVNSEGETLSRAVDSAGAKIRSAR--LPEAQSEVEALQDQADNLERITNNLCNIPNVT 387
Cdd:TIGR02168 436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEreLAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 388 RTEP-------------------------------VIQKSKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSS 436
Cdd:TIGR02168 516 SGLSgilgvlselisvdegyeaaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 437 FIGAFDDELKGLEKVSIDKEKLAEQRRQTQDLVDKHSEGNAILDDVEAIAQKVTAEDP--SKTGSAQKSVGELGARLQRQ 514
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSSILER 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 515 ASELKARGDKINKLDSKAtsfAESEAAVLGYiEKQKDQLSTGFPVPATKEGVKSQLLDLERMN--KTGKEEQRRVDDARH 592
Cdd:TIGR02168 676 RREIEELEEKIEELEEKI---AELEKALAEL-RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQ 751
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 593 SAREL----AREASVEKEVQDMNQREKKLLDEWEDLADQFDAVRSRANKAE------------------QVLNECAQMEK 650
Cdd:TIGR02168 752 LSKELteleAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRealdelraeltllneeaaNLRERLESLER 831
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 651 YIGAKKNMLEGIgapstepgvakanRAQIQSMKAETEGEKSALEHVNSLANELIADgganVEELMKKMDRLNRKWHSLES 730
Cdd:TIGR02168 832 RIAATERRLEDL-------------EEQIEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRS 894
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 731 GLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKAsamssndigdqLATLDSLKSRFGGvdkaleklkgilEATE 810
Cdd:TIGR02168 895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL-----------EVRIDNLQERLSE------------EYSL 951
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 811 ELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDEL 864
Cdd:TIGR02168 952 TLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFL 1005
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
676-1206 |
8.78e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.59 E-value: 8.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 676 RAQIQSMKAETEG--EKSALEHVNSLANELiADGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQ 753
Cdd:PRK02224 186 RGSLDQLKAQIEEkeEKDLHERLNGLESEL-AELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLR 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 754 -----------------KELRKELGELESNVEKA---SAMSSNDIGDQLATLDSLKSRFGGVDKALEKLK-GILEATEEL 812
Cdd:PRK02224 265 etiaeterereelaeevRDLRERLEELEEERDDLlaeAGLDDADAEAVEARREELEDRDEELRDRLEECRvAAQAHNEEA 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 813 EVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELElaapiAAESLkLADEL 892
Cdd:PRK02224 345 ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG-----NAEDF-LEELR 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 893 KRAEELFQKLIENEGDVSLIRAKVAE---------------ELKKKPDAElkkklellyqkwpkalgAARDRKDLVSKAG 957
Cdd:PRK02224 419 EERDELREREAELEATLRTARERVEEaealleagkcpecgqPVEGSPHVE-----------------TIEEDRERVEELE 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 958 DLVKQFGDQVQALEQRLqgDQAEldellasdkahdpevcdalKLVELtmARRLADV-DALNAVMNRIESSAPGPDANR-- 1034
Cdd:PRK02224 482 AELEDLEEEVEEVEERL--ERAE-------------------DLVEA--EDRIERLeERREDLEELIAERRETIEEKRer 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1035 ---LRRRADTLSDDAKGMAKKARTAADLAQRKQGLAKKFERlcdevsqftenQKAEIQDAIEkdllNAERVQSKLNKIDD 1111
Cdd:PRK02224 539 aeeLRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNS-----------KLAELKERIE----SLERIRTLLAAIAD 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1112 fwssNSRELKNVGDEIKIDATPEDAQAvdTKLAELQAGIDGLLATLQEQNVhlEEKREQANRVQSESQKAAGKINSLVAE 1191
Cdd:PRK02224 604 ----AEDEIERLREKREALAELNDERR--ERLAEKRERKRELEAEFDEARI--EEAREDKERAEEYLEQVEEKLDELREE 675
|
570
....*....|....*.
gi 1143463347 1192 IADL-DPIGRSRDELQ 1206
Cdd:PRK02224 676 RDDLqAEIGAVENELE 691
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2596-2811 |
2.06e-08 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 57.46 E-value: 2.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2596 QAVALESALNDMEDWIIAAERKLTDQPSISRLPDViEKQLAEHESWMEEVAGRKMAMTKHQASGVHM--QYYCEKKDaip 2673
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSSTDYGDDLESV-EALLKKHEALEAELAAHEERVEALNELGEQLieEGHPDAEE--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2674 IKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDgLHDLEHFISDVLVKIAPEPnTTSSLEKLKAKLEEVKEAQRD 2753
Cdd:cd00176 77 IQERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASED-LGKDLESVEELLKKHKELEEE 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1143463347 2754 VTAKQTLFDVTRKRGIGLAERATRSEYKQISMTNEKMSKKWAEMLKKLRDRLREAEQA 2811
Cdd:cd00176 155 LEAHEPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
102-764 |
2.19e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 60.52 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 102 QDLISFQNRLHAMNDEHSEQA--RRADEWLQ-----MLQNDVEDVDQDPRFQRD--EDRIQRIEELNRMAAGGS------ 166
Cdd:pfam15921 110 QSVIDLQTKLQEMQMERDAMAdiRRRESQSQedlrnQLQNTVHELEAAKCLKEDmlEDSNTQIEQLRKMMLSHEgvlqei 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 167 -SQLDDAEQASRRLLTALE----------GTNVANDVRARHEELANLRrGKHQKVIDRLSqnmmeaaSRKAEAEgvkQAV 235
Cdd:pfam15921 190 rSILVDFEEASGKKIYEHDsmstmhfrslGSAISKILRELDTEISYLK-GRIFPVEDQLE-------ALKSESQ---NKI 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 236 ENLRQWSEQTAQRTRQPVQLPLTELDLHEARKDEQVlhGEIENRLALIEELEKKAadvgDHASLAELQECKMKLKRSNSD 315
Cdd:pfam15921 259 ELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQA--NSIQSQLEIIQEQARNQ----NSMYMRQLSDLESTVSQLRSE 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 316 LKGLRDNIFDAINGLQT----VNSEgetlsravdsagakirsarLPEAQSEVEALQDQADNLERITNNLcnIPNVTRTEP 391
Cdd:pfam15921 333 LREAKRMYEDKIEELEKqlvlANSE-------------------LTEARTERDQFSQESGNLDDQLQKL--LADLHKREK 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 392 VIQKSKDLRKR-----------VDSCAQELDARMGKLAELESL-DAEFDGAKNKLSSFIGAFDDELKGLEKVSidkeKLA 459
Cdd:pfam15921 392 ELSLEKEQNKRlwdrdtgnsitIDHLRRELDDRNMEVQRLEALlKAMKSECQGQMERQMAAIQGKNESLEKVS----SLT 467
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 460 EQRRQTQDLVDKHSEgnailddvEAIAQKVTAEdpsktgSAQKSVGELGARLQRQASELKARGDKINKLDSKAtsfaESE 539
Cdd:pfam15921 468 AQLESTKEMLRKVVE--------ELTAKKMTLE------SSERTVSDLTASLQEKERAIEATNAEITKLRSRV----DLK 529
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 540 AAVLGYIEKQKDQLSTgfpVPATKEGVKSQLLDLERMNKTGKEE-----QRRVDDARHSARELAREASVEKEVQD--MNQ 612
Cdd:pfam15921 530 LQELQHLKNEGDHLRN---VQTECEALKLQMAEKDKVIEILRQQienmtQLVGQHGRTAGAMQVEKAQLEKEINDrrLEL 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 613 REKKLLDEWEDL-----------------------ADQFDAVRSRANKAEQVLNECAQ--------MEKYIGAKKNMLEg 661
Cdd:pfam15921 607 QEFKILKDKKDAkirelearvsdlelekvklvnagSERLRAVKDIKQERDQLLNEVKTsrnelnslSEDYEVLKRNFRN- 685
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 662 igapSTEPGVAKANRAQIQSMKAETEGEKSAlehvNSLANELIADGGA-NVEELMKK--------MDRLNRKWHSLESGL 732
Cdd:pfam15921 686 ----KSEEMETTTNKLKMQLKSAQSELEQTR----NTLKSMEGSDGHAmKVAMGMQKqitakrgqIDALQSKIQFLEEAM 757
|
730 740 750
....*....|....*....|....*....|....*..
gi 1143463347 733 dENAGR-----VEEAAKLGQELKDIQKELRKELGELE 764
Cdd:pfam15921 758 -TNANKekhflKEEKNKLSQELSTVATEKNKMAGELE 793
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
2270-2373 |
2.31e-08 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 54.25 E-value: 2.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLlkmSPVEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQLAaDAPPHLAATVRQP 2349
Cdd:pfam00435 6 FFRDADDLESWIEEKEALL---SSEDYGKDLESVQALLKKHKALEAELAAHQDRVEALNELAEKLI-DEGHYASEEIQER 81
|
90 100
....*....|....*....|....
gi 1143463347 2350 VADLNTRWSRLNAALAEREHKLEN 2373
Cdd:pfam00435 82 LEELNERWEQLLELAAERKQKLEE 105
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
811-1559 |
3.32e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.15 E-value: 3.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 811 ELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELELAAPIA---AESLK 887
Cdd:PTZ00121 1049 DEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkkAEDAR 1128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 888 LADELKRAEElfqklienegdvslirAKVAEELKKKPDAelkkklellyQKWPKALGAARDRKDLVSKAGDLVKQFGDQV 967
Cdd:PTZ00121 1129 KAEEARKAED----------------ARKAEEARKAEDA----------KRVEIARKAEDARKAEEARKAEDAKKAEAAR 1182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 968 QALEQRLQGDQAELDELLASDKAHDPEvcDALKLVEltmARRLADVDALNAVMNRIESSAPGPDAnrlrRRADTLSDDAK 1047
Cdd:PTZ00121 1183 KAEEVRKAEELRKAEDARKAEAARKAE--EERKAEE---ARKAEDAKKAEAVKKAEEAKKDAEEA----KKAEEERNNEE 1253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1048 GMAKKARTAADLAQRKQGLAKKFERLCDEVSQFTENQKA-EIQDAIEKDLLNAERVQSKLNKIDDFWSSNSRELKNVGDE 1126
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADA 1333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1127 IKIDATpEDAQAVDTKLAELQAGIDGLLATlqeqnvhlEEKREQANRVQSESQKAAGKINSLVAEIADLDPIGRSRDELQ 1206
Cdd:PTZ00121 1334 AKKKAE-EAKKAAEAAKAEAEAAADEAEAA--------EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1207 KQKKEVVELAgdlgSAQTKMLELGAEWEAALGAGIVAQPVFEMNRAatDELNKLAARAGKrlAQREKKITETEDEIDKLH 1286
Cdd:PTZ00121 1405 KKADELKKAA----AAKKKADEAKKKAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKK--AEEAKKKAEEAKKADEAK 1476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1287 ADADQIVGALEAIAKDEALQGAPSQLLDPKQVSEKVRQLK--------ESLKPVGEKMDAfntdcklliKTAGPESDTKE 1358
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKkaeeakkaDEAKKAEEAKKA---------DEAKKAEEKKK 1547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1359 LDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSAD-------AKVAKAQLHD 1431
Cdd:PTZ00121 1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeakkaeeAKIKAEELKK 1627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1432 YEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAV----DLAERLQEV 1507
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALkkeaEEAKKAEEL 1707
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 1143463347 1508 TIPLDSWLQSADKRLQALAKVPITVEKAEEMIGEQEALQDELEHKSDDLKDV 1559
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKI 1759
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
639-1212 |
3.60e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.69 E-value: 3.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 639 EQVLNECAQMEKYIGAKKNMLEgigapstepgVAKANRAQIQSMKAETEGEKSAlehvnslaNELIADGGANVEELMKKM 718
Cdd:PRK03918 148 EKVVRQILGLDDYENAYKNLGE----------VIKEIKRRIERLEKFIKRTENI--------EELIKEKEKELEEVLREI 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 719 DRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKasamssndigdqlatLDSLKSRFGGVDKA 798
Cdd:PRK03918 210 NEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---------------IRELEERIEELKKE 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 799 LEKLKGILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELiGTVNSAENELELA 878
Cdd:PRK03918 275 IEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKR 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 879 APIAAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEELKKKPDAELKKKLELLYQKWPKALGAARDRKDLVSK--- 955
Cdd:PRK03918 354 LEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkk 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 956 ----------------AGDLVKQFGDQVQALEQRLQGDQAELDELLASDKAHDPEVCDALKLVEL-TMARRLADVDALNA 1018
Cdd:PRK03918 434 akgkcpvcgrelteehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLkELAEQLKELEEKLK 513
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1019 VMNRIESSAPGPDANRLRRRADTLSDDAKGMAKKARTAADLAQRKQGLAKKFERLcdevsqftENQKAEIQDAI-EKDLL 1097
Cdd:PRK03918 514 KYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDEL--------EEELAELLKELeELGFE 585
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1098 NAERVQSKLNKIDDFWsSNSRELKNVGDEI-----KIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHL--EEKREQ 1170
Cdd:PRK03918 586 SVEELEERLKELEPFY-NEYLELKDAEKELereekELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYseEEYEEL 664
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 1143463347 1171 ANRVQSESQKAAGK------INSLVAEIA-DLDPIGRSRDELQKQKKEV 1212
Cdd:PRK03918 665 REEYLELSRELAGLraeleeLEKRREEIKkTLEKLKEELEEREKAKKEL 713
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
46-778 |
7.58e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 58.59 E-value: 7.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 46 LKTIGASVLKI----EQEISAMRDDVrasgstddvgISVDEVYETRRRVEDDYMQLLRQcqdliSFQNRLHAMNDEH--- 118
Cdd:pfam15921 215 FRSLGSAISKIlrelDTEISYLKGRI----------FPVEDQLEALKSESQNKIELLLQ-----QHQDRIEQLISEHeve 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 119 ----SEQARRADEWLQMLQNDVEDVDQDPRFQ----------------------RDEDRI--QRIEELNRMAAGGSSQLD 170
Cdd:pfam15921 280 itglTEKASSARSQANSIQSQLEIIQEQARNQnsmymrqlsdlestvsqlrselREAKRMyeDKIEELEKQLVLANSELT 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 171 DAE-------QASRRLLTALEgtNVANDVRARHEELAnLRRGKHQKVIDRLSQNMM-------EAASRKAEAEGVKQAVE 236
Cdd:pfam15921 360 EARterdqfsQESGNLDDQLQ--KLLADLHKREKELS-LEKEQNKRLWDRDTGNSItidhlrrELDDRNMEVQRLEALLK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 237 NLRqwSEQTAQRTRQPVQLPLTELDLHEARKDEQVLHGEIENRLALIEELEKKAADVGDHASL-----AELQECKMKLKR 311
Cdd:pfam15921 437 AMK--SECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTvsdltASLQEKERAIEA 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 312 SNSDLKGLRDNIFDAINGLQTVNSEGETLsRAVDSAGAKIRsARLPEAQSEVEALQDQADNLERItnnlcnIPNVTRTEP 391
Cdd:pfam15921 515 TNAEITKLRSRVDLKLQELQHLKNEGDHL-RNVQTECEALK-LQMAEKDKVIEILRQQIENMTQL------VGQHGRTAG 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 392 VIQKSK-DLRKRVDSCAQEL-------DARMGKLAELESLDAEFDGAKNKLssfIGAFDDELKGLEKVSIDKEKLAEQRR 463
Cdd:pfam15921 587 AMQVEKaQLEKEINDRRLELqefkilkDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVK 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 464 QTQdlvdkhSEGNAILDDVEAIAQKVTaedpSKTGSAQKSVGELGARLQRQASELKARGDKINKL---DSKATSFAESEA 540
Cdd:pfam15921 664 TSR------NELNSLSEDYEVLKRNFR----NKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMegsDGHAMKVAMGMQ 733
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 541 AVLGYIEKQKDQLSTgfpvpatkegvKSQLLDlERMNKTGKEEQRRVDDARHSARELAREAS----VEKEVQDMNQREKK 616
Cdd:pfam15921 734 KQITAKRGQIDALQS-----------KIQFLE-EAMTNANKEKHFLKEEKNKLSQELSTVATeknkMAGELEVLRSQERR 801
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 617 LLDEWEDLADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNM----LEGIG---APSTEPGVAK-ANRAQIQSMKAETEG 688
Cdd:pfam15921 802 LKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLdvkeLQGPGytsNSSMKPRLLQpASFTRTHSNVPSSQS 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 689 EKSALEHVNSLANELIADGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKD--IQKELRKELGELESN 766
Cdd:pfam15921 882 TASFLSHHSRKTNALKEDPTRDLKQLLQELRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDciIESSLRSDICHSSSN 961
|
810
....*....|..
gi 1143463347 767 VEKASAMSSNDI 778
Cdd:pfam15921 962 SLQTEGSKSSET 973
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
590-962 |
1.22e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 590 ARHSARELAREASVEKEVQDMNQREKKLLDEWEDLADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNMLEGigAPSTEP 669
Cdd:TIGR02169 659 SRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ--EEEKLK 736
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 670 GVAKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDRLNRKwhslesgldenagRVEEAAKLGQEL 749
Cdd:TIGR02169 737 ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS-------------RIPEIQAELSKL 803
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 750 KDIQKELRKELGELEsnvekasamssndigdqlATLDSLKSRFGGVDKALEKLKGILEATEElevdatNRAEIQEQLETT 829
Cdd:TIGR02169 804 EEEVSRIEARLREIE------------------QKLNRLTLEKEYLEKEIQELQEQRIDLKE------QIKSIEKEIENL 859
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 830 QKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENEL-ELAAPIAAESLKLADELKRAEELFQKLIENEGD 908
Cdd:TIGR02169 860 NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIeELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 909 VSLIRAKVAEELK-KKPDAELKKKLELLYQKWPKALGAARDRKDLVSKAGDLVKQ 962
Cdd:TIGR02169 940 KGEDEEIPEEELSlEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEK 994
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2743-3162 |
1.40e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 1.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2743 KLEEVKEAQ--RDVTAKQTLFDVTRKRGIGLAERATRSE-------YKQISMTNEKMSKKWAEMLKKLRDRLREAEQAV- 2812
Cdd:PTZ00121 1165 KAEEARKAEdaKKAEAARKAEEVRKAEELRKAEDARKAEaarkaeeERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKk 1244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2813 LEGGAFEESMNDLESWVDDELERYQKAEHEPVFADIDGVRALvdEESRRSAERKTKENGVKTVVKKADALMASGVDE-KD 2891
Cdd:PTZ00121 1245 AEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKA--EEKKKADEAKKAEEKKKADEAKKKAEEAKKADEaKK 1322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2892 SIAQAKERLVEKWNQVEEAARHRGNSIKEAEQAAEEFD-AKTHALLDWLAVEEQKLKASGLDEVEGVKQEMDEAKGRYQE 2970
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEaAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2971 CLKKGEEIlsKCQPAAEPILRNWMRVVEARWKEVSEKVDEREFTLLEQEQKAKEQNEQIEKLAKFAAQKR--EELNRMIE 3048
Cdd:PTZ00121 1403 DKKKADEL--KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKkaDEAKKKAE 1480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 3049 QppAQDLDTMEQNICDFANLDSELREQQPEVDAACKSAKKGARNPAAEMLSTEWKKlwlDAMGLQSSLDNQKAllEEMKR 3128
Cdd:PTZ00121 1481 E--AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK---KADEAKKAEEKKKA--DELKK 1553
|
410 420 430
....*....|....*....|....*....|....
gi 1143463347 3129 LEGWKWEDWKeRYVEWNDHAKARVNDLFRRIDRL 3162
Cdd:PTZ00121 1554 AEELKKAEEK-KKAEEAKKAEEDKNMALRKAEEA 1586
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
732-1268 |
2.57e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 2.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 732 LDENA--GRVEEAAKLGQELKDIQKELRKE------LGELESNVEKASAMSsndigDQLATLDSLKSRFggvdKALEKLK 803
Cdd:COG4913 218 LEEPDtfEAADALVEHFDDLERAHEALEDAreqielLEPIRELAERYAAAR-----ERLAELEYLRAAL----RLWFAQR 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 804 GILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLE-LEKKLDELIGTVNSAENELE------ 876
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRArleall 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 877 --LAAPIAAESLKLADELKRAEELFQKLIENEGDVS--LIRAKVAEELKKKPDAELKKKLELLYQK---WPKALGAARDR 949
Cdd:COG4913 369 aaLGLPLPASAEEFAALRAEAAALLEALEEELEALEeaLAEAEAALRDLRRELRELEAEIASLERRksnIPARLLALRDA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 950 --KDLVSKAGDLvKQFGD--QVQALEQRLQ-------GDQAeLDeLLASDKAHDpevcDALKLVELTMARRLADVDALNA 1018
Cdd:COG4913 449 laEALGLDEAEL-PFVGEliEVRPEEERWRgaiervlGGFA-LT-LLVPPEHYA----AALRWVNRLHLRGRLVYERVRT 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1019 VMNRIESSAPGPDA-----------------NRLRRRAD--------TLSDDAK-----GMAKKARTAADLAQRKQGL-- 1066
Cdd:COG4913 522 GLPDPERPRLDPDSlagkldfkphpfrawleAELGRRFDyvcvdspeELRRHPRaitraGQVKGNGTRHEKDDRRRIRsr 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1067 -------AKKFERLCDEVSQFTE--NQKAEIQDAIEKDLLNAERVQSKLNKIDDFWSsnsrelknvgDEIKIDATPEDAQ 1137
Cdd:COG4913 602 yvlgfdnRAKLAALEAELAELEEelAEAEERLEALEAELDALQERREALQRLAEYSW----------DEIDVASAEREIA 671
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1138 AVDTKLAELQAGiDGLLATLQEQnvhLEEKREQANRVQSESQKAAGKINSLVAEIADLdpigrsrDELQKQKKEVVELAG 1217
Cdd:COG4913 672 ELEAELERLDAS-SDDLAALEEQ---LEELEAELEELEEELDELKGEIGRLEKELEQA-------EEELDELQDRLEAAE 740
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 1218 DLGSAQTKmLELGAEWEAALGAGIVAQpVFEMNRAATDELNKLAARAGKRL 1268
Cdd:COG4913 741 DLARLELR-ALLEERFAAALGDAVERE-LRENLEERIDALRARLNRAEEEL 789
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2494-2591 |
3.52e-07 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 50.79 E-value: 3.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2494 EVEKWQRWLEETEsALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEEPQDADTwLSKTHGAMK 2573
Cdd:smart00150 6 DADELEAWLEEKE-QLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEE-IEERLEELN 83
|
90
....*....|....*...
gi 1143463347 2574 TKWNKVKELLVDREKKLQ 2591
Cdd:smart00150 84 ERWEELKELAEERRQKLE 101
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2818-2919 |
1.28e-06 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 49.25 E-value: 1.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2818 FEESMNDLESWVDdelERYQKAEHEPVFADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQAK 2897
Cdd:smart00150 3 FLRDADELEAWLE---EKEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 1143463347 2898 ERLVEKWNQVEEAARHRGNSIK 2919
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
2925-3126 |
1.30e-06 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 52.06 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2925 AEEFDAKTHALLDWLAVEEQKLKASG-----------LDEVEGVKQEMDEAKGRYQECLKKGEEILSKCQPAAEPIlRNW 2993
Cdd:cd00176 2 LQQFLRDADELEAWLSEKEELLSSTDygddlesvealLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEI-QER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2994 MRVVEARWKEVSEKVDEREfTLLEQEQKAKEQNEQIEKLAKFAAQKREELNRmieQPPAQDLDTMEQNICDFANLDSELR 3073
Cdd:cd00176 81 LEELNQRWEELRELAEERR-QRLEEALDLQQFFRDADDLEQWLEEKEAALAS---EDLGKDLESVEELLKKHKELEEELE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1143463347 3074 EQQPEVDAACKSAKK------GARNPAAEMLSTEWKKLWLDamgLQSSLDNQKALLEEM 3126
Cdd:cd00176 157 AHEPRLKSLNELAEElleeghPDADEEIEEKLEELNERWEE---LLELAEERQKKLEEA 212
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
136-649 |
1.50e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 54.28 E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 136 VEDV--DQDPRFQRDEDRIQRIEE------LNRMAAGGSSQLDDAEQASRRLLTALEGTNVANDVRARHEElanlrrgkH 207
Cdd:PRK02224 178 VERVlsDQRGSLDQLKAQIEEKEEkdlherLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEE--------R 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 208 QKVIDRLSQNMMEAASRKAEAEGVKQAVenlrqwSEQTAQRTRQPVQLpltELDLHEARKDEQVLHGEIENRLALIEELE 287
Cdd:PRK02224 250 REELETLEAEIEDLRETIAETEREREEL------AEEVRDLRERLEEL---EEERDDLLAEAGLDDADAEAVEARREELE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 288 KKAADVGDhaslaELQECKMKLKRSNSDLKGLRDNIFDAINGLQTVNSEGETLSRAVDSAGAKI--RSARLPEAQSEVEA 365
Cdd:PRK02224 321 DRDEELRD-----RLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVedRREEIEELEEEIEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 366 LQDQ------------------ADNLERITNNLCNIPNVTRT-EPVIQKSKDLRK--RVDSCAQE---------LDARMG 415
Cdd:PRK02224 396 LRERfgdapvdlgnaedfleelREERDELREREAELEATLRTaRERVEEAEALLEagKCPECGQPvegsphvetIEEDRE 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 416 KLAELESLDAEFDGAKNKLSSFIgafdDELKGLEKVSIDKEKLAEQRRQTQDLVDKHSEG-----------NAILDDVEA 484
Cdd:PRK02224 476 RVEELEAELEDLEEEVEEVEERL----ERAEDLVEAEDRIERLEERREDLEELIAERRETieekreraeelRERAAELEA 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 485 IAQKVTAEDPSKTGSAQKSVGELGArLQRQASELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQlstgfpvpATKE 564
Cdd:PRK02224 552 EAEEKREAAAEAEEEAEEAREEVAE-LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREAL--------AELN 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 565 GVKSQLLDLERMNKT---GKEEQRRVDDARhSARELARE--ASVEKEVQDMNQREKKL----------LDEWEDLADQFD 629
Cdd:PRK02224 623 DERRERLAEKRERKReleAEFDEARIEEAR-EDKERAEEylEQVEEKLDELREERDDLqaeigaveneLEELEELRERRE 701
|
570 580
....*....|....*....|
gi 1143463347 630 AVRSRANKAEQVLNECAQME 649
Cdd:PRK02224 702 ALENRVEALEALYDEAEELE 721
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
727-984 |
1.50e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 727 SLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIgdqlatlDSLKSRFGGVDKALEKLKGIL 806
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ-------LRVKEKIGELEAEIASLERSI 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 807 EATE-ELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELigtvnsaENELElaaPIAAES 885
Cdd:TIGR02169 311 AEKErELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL-------RAELE---EVDKEF 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 886 LKLADELKRAEELFQKLIENEGDVSLIRAKVAEELKKKPD--AELKKKLELLYQKWPKALGAARDRKDLVSKAGDLVKQF 963
Cdd:TIGR02169 381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEelADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460
|
250 260
....*....|....*....|.
gi 1143463347 964 GDQVQALEQRLQGDQAELDEL 984
Cdd:TIGR02169 461 AADLSKYEQELYDLKEEYDRV 481
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
511-880 |
1.85e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 1.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 511 LQRQASELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQLSTGFPVPATK-EGVKSQLLDLERMNKTGKEEQRRVdD 589
Cdd:TIGR02169 686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERlEELEEDLSSLEQEIENVKSELKEL-E 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 590 ARHSARELAREAsVEKEVQDMNQRE-----KKLLDEWEDLADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNMLEGIGA 664
Cdd:TIGR02169 765 ARIEELEEDLHK-LEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 665 PSTEPgvAKANRAQIQSMKAETEGEKSALEHVNSLANELIADgganVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAK 744
Cdd:TIGR02169 844 DLKEQ--IKSIEKEIENLNGKKEELEEELEELEAALRDLESR----LGDLKKERDELEAQLRELERKIEELEAQIEKKRK 917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 745 LGQELKDIQKELRKELGELESNVEKASAMSSNDigdqlATLDSLKSRFGGVDKALEKLKGI-LEATEELEVDATNRAEIQ 823
Cdd:TIGR02169 918 RLSELKAKLEALEEELSEIEDPKGEDEEIPEEE-----LSLEDVQAELQRVEEEIRALEPVnMLAIQEYEEVLKRLDELK 992
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1143463347 824 EQLETTQKKADELERKIENVKKAALNAQNEGLE-LEKKLDELIGTVNSAENELELAAP 880
Cdd:TIGR02169 993 EKRAKLEEERKAILERIEEYEKKKREVFMEAFEaINENFNEIFAELSGGTGELILENP 1050
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
388-902 |
3.02e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.53 E-value: 3.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 388 RTEPVIQKSKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGafddELKGLEkvsidkEKLAEQRRQTQD 467
Cdd:PRK03918 201 ELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEG----SKRKLE------EKIRELEERIEE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 468 LVDKHSEGNAILDDVEAIAQKVTA-----EDPSKTGSAQKSVGELGARLQRQASELKARGDKINKLDSKATSFAESEAAV 542
Cdd:PRK03918 271 LKKEIEELEEKVKELKELKEKAEEyiklsEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKEL 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 543 ---LGYIEKQKDQLSTGFPVPATKEGVKSQL--LDLERMNKTGKEEQRRVDDARHSAREL-AREASVEKEVQDMNQREKK 616
Cdd:PRK03918 351 ekrLEELEERHELYEEAKAKKEELERLKKRLtgLTPEKLEKELEELEKAKEEIEEEISKItARIGELKKEIKELKKAIEE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 617 L-------------LDEwEDLADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRAQIQSMK 683
Cdd:PRK03918 431 LkkakgkcpvcgreLTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELE 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 684 AETEG--------EKSALEHVNSLANEL------IADGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEaakLGQEL 749
Cdd:PRK03918 510 EKLKKynleelekKAEEYEKLKEKLIKLkgeiksLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE---LGFES 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 750 KDiqkELRKELGELESNVEKASAMSS--NDIGDQLATLDSLKSRfggVDKALEKLKGILEATEEL--EVDATNRAEIQEQ 825
Cdd:PRK03918 587 VE---ELEERLKELEPFYNEYLELKDaeKELEREEKELKKLEEE---LDKAFEELAETEKRLEELrkELEELEKKYSEEE 660
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1143463347 826 LETTQKKADELERKIenvkkAALNAQNEglELEKKLDELIGTVNSAENELELAAPIAAESLKLADELKRAEELFQKL 902
Cdd:PRK03918 661 YEELREEYLELSREL-----AGLRAELE--ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
500-918 |
3.34e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 53.12 E-value: 3.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 500 AQKSVGELGARLQRQASELKARGDKINKLDSK---ATSFAESEAAVLGYIEKQKDQLSTgfpVPATKEGVKSQLLDLERM 576
Cdd:PRK02224 197 EEKEEKDLHERLNGLESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELET---LEAEIEDLRETIAETERE 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 577 NKTGKEEQRRVDDARHSARELAREASVEKEVQDMNQrekklldewEDLADQFDAVRSRANKAEQVLNECAQMekyIGAKK 656
Cdd:PRK02224 274 REELAEEVRDLRERLEELEEERDDLLAEAGLDDADA---------EAVEARREELEDRDEELRDRLEECRVA---AQAHN 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 657 NMLEGigapstepgvAKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDRLNRKWHSLESGLDENA 736
Cdd:PRK02224 342 EEAES----------LREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 737 GRVEEAAKLGQELKDIQKELRKELGELESNVEKASAM------------------------SSNDIGDQLATLDSLKSRF 792
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVEEAEALleagkcpecgqpvegsphvetieeDRERVEELEAELEDLEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 793 GGVDKALEKLKGILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGtvnSAE 872
Cdd:PRK02224 492 EEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE---EAE 568
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1143463347 873 NELELAAPIAAESLKLADE---LKRAEELFQKLIENEGDVSLIRAKVAE 918
Cdd:PRK02224 569 EAREEVAELNSKLAELKERiesLERIRTLLAAIADAEDEIERLREKREA 617
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
728-1421 |
3.36e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.20 E-value: 3.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 728 LESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKSRFGGVDKALEKLKGILE 807
Cdd:pfam15921 115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 808 ATEEL------EVDATNRAEIQEQLETTQKKADELERKIENVKK---------AALNAQNEG---LELEKKLDELIGTVN 869
Cdd:pfam15921 195 DFEEAsgkkiyEHDSMSTMHFRSLGSAISKILRELDTEISYLKGrifpvedqlEALKSESQNkieLLLQQHQDRIEQLIS 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 870 SAENELELAAPIAAESLKLADELKRAEELFQKLIEN------------EGDVSLIRAKVAEELKKKPDA--ELKKKLELL 935
Cdd:pfam15921 275 EHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNqnsmymrqlsdlESTVSQLRSELREAKRMYEDKieELEKQLVLA 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 936 YQKwpkaLGAARDRKDLVSK-AGDLvkqfGDQVQALEQRLQGDQAELDellasdkahdpevcdalklVELTMARRLADVD 1014
Cdd:pfam15921 355 NSE----LTEARTERDQFSQeSGNL----DDQLQKLLADLHKREKELS-------------------LEKEQNKRLWDRD 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1015 ALNAVMN---RIESSAPGPDANRLRRRADTLSDDAKGMAKKARTAAdlaqrkQGLAKKFERLCDEVSQFtENQKAEIQDA 1091
Cdd:pfam15921 408 TGNSITIdhlRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI------QGKNESLEKVSSLTAQL-ESTKEMLRKV 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1092 IEKDLLNAERVQSKLNKIDDFWSSNSRELKNVgdeikidatpedaQAVDTKLAELQAGIDGLLATLQeqnvHLEEKREQA 1171
Cdd:pfam15921 481 VEELTAKKMTLESSERTVSDLTASLQEKERAI-------------EATNAEITKLRSRVDLKLQELQ----HLKNEGDHL 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1172 NRVQSESQkaagkinSLVAEIADLDPIgrsRDELQKQKKEVVELAGDLGSAQTKMLELGAEWEAalgagivaqpvfEMN- 1250
Cdd:pfam15921 544 RNVQTECE-------ALKLQMAEKDKV---IEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK------------EINd 601
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1251 -RAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIA--KDEALQGAPSQLLDPKQVSEKVRQLKE 1327
Cdd:pfam15921 602 rRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKqeRDQLLNEVKTSRNELNSLSEDYEVLKR 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1328 SLKPVGEKMDAFNTDCKLLIKTAGPESDTKE--LDSLLKKVGDAYSDVVG---KVSDKEMSVDAAvqqQGKVEDAYRALL 1402
Cdd:pfam15921 682 NFRNKSEEMETTTNKLKMQLKSAQSELEQTRntLKSMEGSDGHAMKVAMGmqkQITAKRGQIDAL---QSKIQFLEEAMT 758
|
730
....*....|....*....
gi 1143463347 1403 NWLEETEEMMENRKKPSAD 1421
Cdd:pfam15921 759 NANKEKHFLKEEKNKLSQE 777
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
264-845 |
5.24e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.37 E-value: 5.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 264 EARKDEQVLHGEIENRlalIEELEKKAADVgdhasLAELQECKMKLKRSNSDLKGLR------DNIFDAINGLQTVNSEG 337
Cdd:PRK03918 179 ERLEKFIKRTENIEEL---IKEKEKELEEV-----LREINEISSELPELREELEKLEkevkelEELKEEIEELEKELESL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 338 ETLSRAVDSAGAKIRSaRLPEAQSEVEALQDQADNLERITNNLCNIPNVTR-TEPVIQKSKDLRKRVDSCAQELDARMGK 416
Cdd:PRK03918 251 EGSKRKLEEKIRELEE-RIEELKKEIEELEEKVKELKELKEKAEEYIKLSEfYEEYLDELREIEKRLSRLEEEINGIEER 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 417 LAELESLDAEFDGAKNKLSSFigafDDELKGLEKvsidKEKLAEQRRQTQDLVDKHSEGNAILDdVEAIAQKVTAEDPSK 496
Cdd:PRK03918 330 IKELEEKEERLEELKKKLKEL----EKRLEELEE----RHELYEEAKAKKEELERLKKRLTGLT-PEKLEKELEELEKAK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 497 TgSAQKSVGELGARLQRQASELKARGDKINKLDSkatsfAESEAAVLGYIEKQKDQlstgfpvpatKEGVKSQLLDLERM 576
Cdd:PRK03918 401 E-EIEEEISKITARIGELKKEIKELKKAIEELKK-----AKGKCPVCGRELTEEHR----------KELLEEYTAELKRI 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 577 NKTGKEEQRRVDDARHSARELAREASVEKEVQdmnqREKKLLDEWEDLADQF-----DAVRSRANKAEQVLNECAQMEKY 651
Cdd:PRK03918 465 EKELKEIEEKERKLRKELRELEKVLKKESELI----KLKELAEQLKELEEKLkkynlEELEKKAEEYEKLKEKLIKLKGE 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 652 IGAKKNMLEGIGApstepgvAKANRAQIQSMKAETEGEKSALEHvnslanELIADGGANVEELMKKMDRLN---RKWHSL 728
Cdd:PRK03918 541 IKSLKKELEKLEE-------LKKKLAELEKKLDELEEELAELLK------ELEELGFESVEELEERLKELEpfyNEYLEL 607
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 729 ESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLD----SLKSRFGGVDKALEKLKG 804
Cdd:PRK03918 608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELReeylELSRELAGLRAELEELEK 687
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 1143463347 805 ILEAT----EELEVDATNRAEIQEQLETTQKKADELERKIENVKK 845
Cdd:PRK03918 688 RREEIkktlEKLKEELEEREKAKKELEKLEKALERVEELREKVKK 732
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
434-901 |
8.35e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 8.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 434 LSSFIGAFDDELKGLEKVS-----IDKEKLAEQRRQTQDLVDKHSEGNAILDDVEAIAQKVtaedpsktgsaqksvgelg 508
Cdd:COG4717 44 RAMLLERLEKEADELFKPQgrkpeLNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL------------------- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 509 ARLQRQASELKARGDKINKLDSKATSFAESEAAvlgyiekqKDQLStgfPVPATKEGVKSQLLDLERMNKTGKEEQRRVD 588
Cdd:COG4717 105 EELEAELEELREELEKLEKLLQLLPLYQELEAL--------EAELA---ELPERLEELEERLEELRELEEELEELEAELA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 589 DARHSARELAREASVEKEvqdmnQREKKLLDEWEDLADQFDAVRSRANKAEQVLNEC-------------AQMEKYIGAK 655
Cdd:COG4717 174 ELQEELEELLEQLSLATE-----EELQDLAEELEELQQRLAELEEELEEAQEELEELeeeleqleneleaAALEERLKEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 656 KNMLEGIGA--------------PSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDRL 721
Cdd:COG4717 249 RLLLLIAAAllallglggsllslILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAAL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 722 NRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKE--LGELESNVEKASAMSSND---IGDQLATLDSLKSRFGGVD 796
Cdd:COG4717 329 GLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEelEQEIAALLAEAGVEDEEElraALEQAEEYQELKEELEELE 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 797 KALEKLKGILEAteelEVDATNRAEIQEQLETTQKKADELERKIENV--KKAALNAQNEGLELEKKLDELIGTVNSAENE 874
Cdd:COG4717 409 EQLEELLGELEE----LLEALDEEELEEELEELEEELEELEEELEELreELAELEAELEQLEEDGELAELLQELEELKAE 484
|
490 500
....*....|....*....|....*...
gi 1143463347 875 LELAApIAAESLKLADE-LKRAEELFQK 901
Cdd:COG4717 485 LRELA-EEWAALKLALElLEEAREEYRE 511
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
535-742 |
1.42e-05 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 48.98 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 535 FAESEAAVLGYIEKQKDQLSTGFPvPATKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARELARE-----ASVEKEVQD 609
Cdd:cd00176 5 FLRDADELEAWLSEKEELLSSTDY-GDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEghpdaEEIQERLEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 610 MNQREKKLLDEWEDLADQFDavrsRANKAEQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRaQIQSMKAETEGE 689
Cdd:cd00176 84 LNQRWEELRELAEERRQRLE----EALDLQQFFRDADDLEQWLEEKEAALASEDLGKDLESVEELLK-KHKELEEELEAH 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 690 KSALEHVNSLANELIADGG-ANVEELMKKMDRLNRKWHSLESGLDENAGRVEEA 742
Cdd:cd00176 159 EPRLKSLNELAEELLEEGHpDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
757-1743 |
1.68e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 1.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 757 RKELGELESNVEKASAMSSnDIGDQLATLDSLKsrfggvDKALE--KLKGILEATEELEVdATNRAEIQEQLETTQKKAD 834
Cdd:TIGR02169 176 LEELEEVEENIERLDLIID-EKRQQLERLRRER------EKAERyqALLKEKREYEGYEL-LKEKEALERQKEAIERQLA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 835 ELERKIEnvkkaalnaqneglELEKKLDELIGTVNSAENEL-ELAAPIAAESLKLADELKRaeelfqKLIENEGDVSLIR 913
Cdd:TIGR02169 248 SLEEELE--------------KLTEEISELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKE------KIGELEAEIASLE 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 914 AKVAEELKKKPDAELK-KKLELLYQKwpKALGAARDRKDLVSKAGDlVKQFGDQVQALEQRLQGDQAELDELlasDKAHD 992
Cdd:TIGR02169 308 RSIAEKERELEDAEERlAKLEAEIDK--LLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEV---DKEFA 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 993 pevcdalKLVELTMARRladvDALNAVMNRIESsapgpdanrLRRRADTLSDDAKGM-AKKARTAADLAQRKQGLAKKFE 1071
Cdd:TIGR02169 382 -------ETRDELKDYR----EKLEKLKREINE---------LKRELDRLQEELQRLsEELADLNAAIAGIEAKINELEE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1072 RLCD---EVSQFTEN--QKAEIQDAIEKDLlnaERVQSKLNKIDDFWSSNSRELKNVGDEIKIDATPE-DAQAVDTKLAE 1145
Cdd:TIGR02169 442 EKEDkalEIKKQEWKleQLAADLSKYEQEL---YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrGGRAVEEVLKA 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1146 LQAGIDGLLATLqeqnvhLEEKREQANRVQSesqkAAGkiNSLVAEIADLDPIGRSRDELQKQKKevvelagdLGSAQ-- 1223
Cdd:TIGR02169 519 SIQGVHGTVAQL------GSVGERYATAIEV----AAG--NRLNNVVVEDDAVAKEAIELLKRRK--------AGRATfl 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1224 --TKMLELGAEWEAALGAGIVA------------QPVFEMNRAATDELNKLAAraGKRLAQREKKITETEDEIDKLHAda 1289
Cdd:TIGR02169 579 plNKMRDERRDLSILSEDGVIGfavdlvefdpkyEPAFKYVFGDTLVVEDIEA--ARRLMGKYRMVTLEGELFEKSGA-- 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1290 dqIVGALEAiakdealqgAPSQLLDPKQVSEKVRQLKESLkpvgEKMDAFNTDCKlliktagpeSDTKELDSLLKKVGDA 1369
Cdd:TIGR02169 655 --MTGGSRA---------PRGGILFSRSEPAELQRLRERL----EGLKRELSSLQ---------SELRRIENRLDELSQE 710
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1370 YSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENrkkpsadakvakaqlhdyevlmkhvedkkpsvdgF 1449
Cdd:TIGR02169 711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------------------------------V 756
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1450 KAMIEKIVAEASSDEEKkaLGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDlaerlqEVTIPLDSWLQSADKRLQALAkvp 1529
Cdd:TIGR02169 757 KSELKELEARIEELEED--LHKLEEALNDLEARLSHSRIPEIQAELSKLE------EEVSRIEARLREIEQKLNRLT--- 825
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1530 ITVEKAEEMIGEQEALQDELEHKSDDLKDVLE-IAPMLASLVSVEDanSISGQVNQLEARARALDAGITNMRPLLESFLQ 1608
Cdd:TIGR02169 826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnLNGKKEELEEELE--ELEAALRDLESRLGDLKKERDELEAQLRELER 903
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1609 QIQDFTLDAEDMTQFVGETEVKLG----ELDELPIEPDDLVEQTNILAEIAVSIADRDEMMANI--FEVGKQLAIQgEPE 1682
Cdd:TIGR02169 904 KIEELEAQIEKKRKRLSELKAKLEaleeELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIraLEPVNMLAIQ-EYE 982
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 1683 EAliaQKKLDDLKFRYADLMTSADEKIALLAKaipLSEGFHEGFdtvMQVLEDMDRDLQTI 1743
Cdd:TIGR02169 983 EV---LKRLDELKEKRAKLEEERKAILERIEE---YEKKKREVF---MEAFEAINENFNEI 1034
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
780-1330 |
1.97e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 1.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 780 DQLATLDSLKSRfggVDKALEK---LKGILEATEELEvDATNRAEIQEQLETT------QKKADELERKIENVKKAALNA 850
Cdd:COG4913 232 EHFDDLERAHEA---LEDAREQielLEPIRELAERYA-AARERLAELEYLRAAlrlwfaQRRLELLEAELEELRAELARL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 851 QNEGLELEKKLDELIGTVNSAENELELAAPIAAESLK-----LADELKRAEELFQKLIENEGDVSLIRAKVAEELkkkpd 925
Cdd:COG4913 308 EAELERLEARLDALREELDELEAQIRGNGGDRLEQLEreierLERELEERERRRARLEALLAALGLPLPASAEEF----- 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 926 AELKKKLELLYQKWPKALGAARDRKDlvskagdlvkQFGDQVQALEQRLQGDQAELDELLASDKAHDPEV-------CDA 998
Cdd:COG4913 383 AALRAEAAALLEALEEELEALEEALA----------EAEAALRDLRRELRELEAEIASLERRKSNIPARLlalrdalAEA 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 999 LK-----------LVEL----------------TMARRL----ADVDALNAVMNRIessapgPDANRLR--------RRA 1039
Cdd:COG4913 453 LGldeaelpfvgeLIEVrpeeerwrgaiervlgGFALTLlvppEHYAAALRWVNRL------HLRGRLVyervrtglPDP 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1040 DTLSDDAKGMAKKARTAADLAQR--KQGLAKKFERLC-DEVSQFTENQKAeiqdaIEKDLLnaervqsklnkiddfwSSN 1116
Cdd:COG4913 527 ERPRLDPDSLAGKLDFKPHPFRAwlEAELGRRFDYVCvDSPEELRRHPRA-----ITRAGQ----------------VKG 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1117 SRELKNVGDEIKIDATP---EDAQAvdtKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQsESQKAAGKINSLVAEIA 1193
Cdd:COG4913 586 NGTRHEKDDRRRIRSRYvlgFDNRA---KLAALEAELAELEEELAEAEERLEALEAELDALQ-ERREALQRLAEYSWDEI 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1194 DLDPIGRSRDELQKQKKEVVELAGDLGsaqtkmlELGAEWEAAlgagivaqpvfemnRAATDELNKLAARAGKRLAQREK 1273
Cdd:COG4913 662 DVASAEREIAELEAELERLDASSDDLA-------ALEEQLEEL--------------EAELEELEEELDELKGEIGRLEK 720
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 1143463347 1274 KITETEDEIDKLHADADQIvGALEAIAKDEALQGAPSQLLDPKQVSEKVRQLKESLK 1330
Cdd:COG4913 721 ELEQAEEELDELQDRLEAA-EDLARLELRALLEERFAAALGDAVERELRENLEERID 776
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1393-1494 |
2.48e-05 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 45.78 E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1393 KVEDAYRALLNWLEETEEMMENrKKPSADAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEasSDEEKKALGNK 1472
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLAS-EDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEE--GHPDAEEIEER 78
|
90 100
....*....|....*....|..
gi 1143463347 1473 NAQIEDRYKDLLNSAVDRQRKL 1494
Cdd:smart00150 79 LEELNERWEELKELAEERRQKL 100
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
24-291 |
2.86e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.32 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 24 RIDEARFEAKSLMDEVIREESRLKTIGASVLKIEQEISAMRDDVRASGStddvgiSVDEVYETRRRVEDDYMQLLRQCQD 103
Cdd:COG1196 247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA------ELARLEQDIARLEERRRELEERLEE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 104 LISFQNRLHAMNDEHSEQARRADEWLQMLQNDVEDVDQdprfQRDEDRIQRIEELNRMAAGGSSQLDDAEQASRRLLTAL 183
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEA----ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 184 EGTNVANDVRARHEELANLRRGKHQKVIDRLSQNMMEAASRKAEAEGVKQAVENLRQWSEQTAQRTRQPVQLPLTELDLH 263
Cdd:COG1196 397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
250 260
....*....|....*....|....*...
gi 1143463347 264 EARKDEQVLHGEIENRLALIEELEKKAA 291
Cdd:COG1196 477 AALAELLEELAEAAARLLLLLEAEADYE 504
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2684-3061 |
5.58e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.37 E-value: 5.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2684 RVEKISgRTAERAKQLAVTRDEVATWQDGLHDLEHFISDVLVKIAPEPNTTSSLEKL--KAKLEEVKEAQRDVTAkqtlf 2761
Cdd:PTZ00121 1231 KAEEAK-KDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAeeKKKADEAKKAEEKKKA----- 1304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2762 DVTRKRgiglAERATRSEykQISMTNEKMSKKWAEMLKKLRDRLREAEQAVLEGgafEESMNDLESWVDDELERYQKAEH 2841
Cdd:PTZ00121 1305 DEAKKK----AEEAKKAD--EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA---EAAADEAEAAEEKAEAAEKKKEE 1375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2842 EPVFADIDGVRAlvdEESRRSAERKTKENGVKtvvKKADALMASGvDEKDSIAQAKERLVEKwnQVEEAARHRGNSIKEA 2921
Cdd:PTZ00121 1376 AKKKADAAKKKA---EEKKKADEAKKKAEEDK---KKADELKKAA-AAKKKADEAKKKAEEK--KKADEAKKKAEEAKKA 1446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2922 EQAAEEFDAKTHALLDWLAVEEQKlKASGLDEVEGVKQEMDEAKGRYQECLKKGEEILSKCQPAAepilrnwmRVVEARW 3001
Cdd:PTZ00121 1447 DEAKKKAEEAKKAEEAKKKAEEAK-KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK--------KADEAKK 1517
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 3002 KEVSEKVDEREFTllEQEQKAKEQNEQIEKLAKFAAQKREELNRMIEQPPAQDLDTMEQN 3061
Cdd:PTZ00121 1518 AEEAKKADEAKKA--EEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
225-843 |
6.71e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 6.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 225 KAEAEgVKQAVENLRQWSEQTAQRTRQPVQLPLTELDLHEARKDEQVLHGEIENRLALIEELEKKAADVGD--HASLAEL 302
Cdd:COG1196 219 KEELK-ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeYELLAEL 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 303 QECKMKLKRSNSDLKGLRDNIFDAINGLQTVNSEGETLSRAVDSAGAKIRSARlPEAQSEVEALQDQADNLERITNNLcn 382
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE-EELEEAEAELAEAEEALLEAEAEL-- 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 383 ipnvtrtepvIQKSKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGAFDDELKGLEKVSIDKEKLAEQR 462
Cdd:COG1196 375 ----------AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 463 RQTQDLVDKHSEGNAILDDVEAIAQKVTAEDPSKTGSAQKSVGELGARLQRQASELKARGDKINKLDSKATSFAESEAAV 542
Cdd:COG1196 445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 543 LGYIEKQKDQLSTGFPVPATKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARELAREASVE-KEVQDMNQREKKLLDEW 621
Cdd:COG1196 525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAaLAAALARGAIGAAVDLV 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 622 EDLADQFDAVRSRANKAEQVLN-ECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLA 700
Cdd:COG1196 605 ASDLREADARYYVLGDTLLGRTlVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 701 NELIADGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGD 780
Cdd:COG1196 685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 781 QLATLDSLKsrfggvdKALEKLKGI-LEATEELEVDATNRAEIQEQLETTQKKADELERKIENV 843
Cdd:COG1196 765 LERELERLE-------REIEALGPVnLLAIEEYEELEERYDFLSEQREDLEEARETLEEAIEEI 821
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
390-1146 |
1.07e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.30 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 390 EPVIQKSKDLRKRVDSCAQELDARMGKLA----ELESLDAEfdgaknklssfIGAFDDElkGLEKVSIDKEKLAEQRRQT 465
Cdd:pfam12128 290 QLLRTLDDQWKEKRDELNGELSAADAAVAkdrsELEALEDQ-----------HGAFLDA--DIETAAADQEQLPSWQSEL 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 466 QDLvdkhsegNAILDDVEAIAQKVTAEdpsktgsAQKSVGELGARLQRQASELKARGDKINklDSKATSFAESEAAVLGY 545
Cdd:pfam12128 357 ENL-------EERLKALTGKHQDVTAK-------YNRRRSKIKEQNNRDIAGIKDKLAKIR--EARDRQLAVAEDDLQAL 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 546 IEKQKDQLSTGF-PVPATKEGVKSQLldlermnktgKEEQRRVDDARHSARELAREASVEKEVQDMNQREKKLLDEWEDL 624
Cdd:pfam12128 421 ESELREQLEAGKlEFNEEEYRLKSRL----------GELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERL 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 625 ADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNMLEGIGAP---------STEPGVAKANRAQIQSmkaetegekSALEH 695
Cdd:pfam12128 491 QSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqagtllhflRKEAPDWEQSIGKVIS---------PELLH 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 696 VNSLANELIADGGANVEELMKKMDRLNR----KWHSLESGLDENAGRVEEAAklgQELKDIQKELRKELGELESNVEKAS 771
Cdd:pfam12128 562 RTDLDPEVWDGSVGGELNLYGVKLDLKRidvpEWAASEEELRERLDKAEEAL---QSAREKQAAAEEQLVQANGELEKAS 638
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 772 AMSSndigDQLATLDSLKSRFG--GVDKALEKLKgILEATEElevdatNRAEIQEQLETTQKKADELERKIenvkKAALN 849
Cdd:pfam12128 639 REET----FARTALKNARLDLRrlFDEKQSEKDK-KNKALAE------RKDSANERLNSLEAQLKQLDKKH----QAWLE 703
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 850 AQNEGL-----ELEKKLDELIGTVNSAENELElaAPIAAESLKLADELK-----RAEELFQKLIENEGDVSLIRaKVAEE 919
Cdd:pfam12128 704 EQKEQKreartEKQAYWQVVEGALDAQLALLK--AAIAARRSGAKAELKaletwYKRDLASLGVDPDVIAKLKR-EIRTL 780
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 920 LKKKPDAELKKKLELLYQKWPKALGAARD--RKDLVSKAGDLVKQFGDQVQALEQRLQGDQAELD-ELLASDKAHDpEVC 996
Cdd:pfam12128 781 ERKIERIAVRRQEVLRYFDWYQETWLQRRprLATQLSNIERAISELQQQLARLIADTKLRRAKLEmERKASEKQQV-RLS 859
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 997 DALKLVELTMaRRLADVdALNAVMNRIESSAPGPDA--NRLRRRADTLSDDAK--------GMAKKARTA---------- 1056
Cdd:pfam12128 860 ENLRGLRCEM-SKLATL-KEDANSEQAQGSIGERLAqlEDLKLKRDYLSESVKkyvehfknVIADHSGSGlaetweslre 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1057 ADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDAIEKDL--LNAERVQSKLNKIDDF---WSSNSREL-KNVGDEIKID 1130
Cdd:pfam12128 938 EDHYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQvsILGVDLTEFYDVLADFdrrIASFSRELqREVGEEAFFE 1017
|
810
....*....|....*.
gi 1143463347 1131 ATPEDAQAVDTKLAEL 1146
Cdd:pfam12128 1018 GVSESAVRIRSKVSEL 1033
|
|
| SPEC |
cd00176 |
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members ... |
1609-1820 |
1.23e-04 |
|
Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; the repeats are independent folding units; tandem repeats are found in differing numbers and arrange in an antiparallel manner to form dimers; the repeats are defined by a characteristic tryptophan (W) residue in helix A and a leucine (L) at the carboxyl end of helix C and separated by a linker of 5 residues; two copies of the repeat are present here
Pssm-ID: 238103 [Multi-domain] Cd Length: 213 Bit Score: 46.28 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1609 QIQDFTLDAEDMTQFVGETEVKLGElDELPIEPDDLVEQTNILAEIAVSIADRDEMMANIFEVGKQLAIQGEPEEALIaQ 1688
Cdd:cd00176 1 KLQQFLRDADELEAWLSEKEELLSS-TDYGDDLESVEALLKKHEALEAELAAHEERVEALNELGEQLIEEGHPDAEEI-Q 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1689 KKLDDLKFRYADLMTSADEKIALLAKAIPLSEGFHEgFDTVMQVLEDMDRDLQTIDEEDPETQAELIF----LLEEDISQ 1764
Cdd:cd00176 79 ERLEELNQRWEELRELAEERRQRLEEALDLQQFFRD-ADDLEQWLEEKEAALASEDLGKDLESVEELLkkhkELEEELEA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1143463347 1765 KmRPSVDELTALSNQLQVLCSADKADELQTNTIAMNKLVNSVADRVARRAERIEMA 1820
Cdd:cd00176 158 H-EPRLKSLNELAEELLEEGHPDADEEIEEKLEELNERWEELLELAEERQKKLEEA 212
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1457-2180 |
2.18e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 2.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1457 VAEASSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEvtipLDSWLQSADKRLQALAKVPITVEKAE 1536
Cdd:TIGR02168 264 ELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN----LERQLEELEAQLEELESKLDELAEEL 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1537 EMIGEQEA-LQDELEHKSDDLKDVLEIAPMLASLVSV--EDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDF 1613
Cdd:TIGR02168 340 AELEEKLEeLKEELESLEAELEELEAELEELESRLEEleEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1614 TLDAEDMTQFVGETEVKL--GELDELPIEPDDLVEQTNILAEIAVSIADRDEMmanifevgKQLAIQGEPEEALIAQKKL 1691
Cdd:TIGR02168 420 QQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEE--------AEQALDAAERELAQLQARL 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1692 DDLKFRYADLMTSADEKIALLAKAI-------PLSEGFH--EGFDTVMQ----------VLEDMDRDLQTIDEEDPETQA 1752
Cdd:TIGR02168 492 DSLERLQENLEGFSEGVKALLKNQSglsgilgVLSELISvdEGYEAAIEaalggrlqavVVENLNAAKKAIAFLKQNELG 571
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1753 ELIFLLEEDISQKmRPSVDELTALSNQLQVLCSADkadELQTNTIAMNKLVNS------VADRVARRAE-RIEMASKQSR 1825
Cdd:TIGR02168 572 RVTFLPLDSIKGT-EIQGNDREILKNIEGFLGVAK---DLVKFDPKLRKALSYllggvlVVDDLDNALElAKKLRPGYRI 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1826 AVLDDLQYLIEWFSAARERILEGAPPSLDLEVLKSQLKHQRITNEEASANKvqfrnvagEAKKVARQLgmegNEANEKIS 1905
Cdd:TIGR02168 648 VTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEK--------ALAELRKEL----EELEEELE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1906 DTVDEGKELVEEVMALCADrtetLERALALMEQLTSQFDELNKWLDQMDAELQASpsvttatpAAELREMHDHNEELARM 1985
Cdd:TIGR02168 716 QLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTELEAEIEEL--------EERLEEAEEELAEAEAE 783
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1986 VAAYRPIIEGFKSDVGSLHEVLAEDQAPL--LESVAGELVQGYEEVREAVRARGHAIDNMMGATIGFGERLETLVANLQG 2063
Cdd:TIGR02168 784 IEELEAQIEQLKEELKALREALDELRAELtlLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2064 AADRLRENE----GISADPSVLESRLAENRSIVESLRDKQNAYDalkQTASELLASAPEGDAAAGDVENKLNRLE-KLWK 2138
Cdd:TIGR02168 864 LEELIEELEseleALLNERASLEEALALLRSELEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEvRIDN 940
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 1143463347 2139 EIEREAVDRGVLLEDVLDKAKHFWSELDSCQKAVDDLRNRLE 2180
Cdd:TIGR02168 941 LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
672-932 |
2.65e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 672 AKANRAQIQSMKAETEGEKSALEHVNSLANELIADgganVEELMKKMDRLNRKWHSLESGLDENAGRVeeaaklgQELKD 751
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ----LAALERRIAALARRIRALEQELAALEAEL-------AELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 752 IQKELRKELGELESNVEK-ASAMSSNDIGDQLATLDSLKSrFGGVDKALEKLKGILEAteelevdatnRAEIQEQLETTQ 830
Cdd:COG4942 91 EIAELRAELEAQKEELAElLRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKYLAPA----------RREQAEELRADL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 831 KKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELELAAPIAAESLKladELKRAEELFQKLIEnegDVS 910
Cdd:COG4942 160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA---ELQQEAEELEALIA---RLE 233
|
250 260
....*....|....*....|..
gi 1143463347 911 LIRAKVAEELKKKPDAELKKKL 932
Cdd:COG4942 234 AEAAAAAERTPAAGFAALKGKL 255
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
816-1057 |
3.00e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 816 ATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELElaapiaaeslKLADELKRA 895
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELA----------ALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 896 EElfqklienegdvsliRAKVAEELKKKPDAELKKKLELLY----QKWPKALGAARDRKDLVsKAGDLVKQFGDQVQALE 971
Cdd:COG4942 89 EK---------------EIAELRAELEAQKEELAELLRALYrlgrQPPLALLLSPEDFLDAV-RRLQYLKYLAPARREQA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 972 QRLQGDQAELDELLASDKAHDPEVCDALKLVELTMARRLADVDALNAVMNRIESSAPG--PDANRLRRRADTLSDDAKGM 1049
Cdd:COG4942 153 EELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAElaAELAELQQEAEELEALIARL 232
|
....*...
gi 1143463347 1050 AKKARTAA 1057
Cdd:COG4942 233 EAEAAAAA 240
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
673-877 |
4.51e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 46.16 E-value: 4.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 673 KANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDrlnrkwhslesgldenagrveEAAKLGQELKDI 752
Cdd:PHA02562 177 RELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD---------------------ELVEEAKTIKAE 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 753 QKELRKELGELESNVEKASAmSSNDIGDQLATLDSLKSRFGGVDKALEK-------LKGILEATEELEVDATNRAEIQEQ 825
Cdd:PHA02562 236 IEELTDELLNLVMDIEDPSA-ALNKLNTAAAKIKSKIEQFQKVIKMYEKggvcptcTQQISEGPDRITKIKDKLKELQHS 314
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1143463347 826 LE-----------------TTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELEL 877
Cdd:PHA02562 315 LEkldtaideleeimdefnEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAK 383
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
639-740 |
7.06e-04 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 41.55 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 639 EQVLNECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANRAQiQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKM 718
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDLGKDLESVEALLKKH-EAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEERL 79
|
90 100
....*....|....*....|..
gi 1143463347 719 DRLNRKWHSLESGLDENAGRVE 740
Cdd:smart00150 80 EELNERWEELKELAEERRQKLE 101
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
677-1296 |
9.31e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.28 E-value: 9.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 677 AQIQSMKAETEGEKSALEHV-NSLANELIadggaNVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKE 755
Cdd:PRK01156 207 ADDEKSHSITLKEIERLSIEyNNAMDDYN-----NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEER 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 756 LRkelgELESNVEKASAMSSNDIGDQLATLDSLKSRFGGVDKALEKLKGILEATEELEVDATNRAEIQEQLETTQKKADE 835
Cdd:PRK01156 282 HM----KIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 836 LE----------RKIENVKKaalNAQNEGLELEKKLDELIGTVNSAEnelelaapIAAESLKladelKRAEELFQKLIEN 905
Cdd:PRK01156 358 LEgyemdynsylKSIESLKK---KIEEYSKNIERMSAFISEILKIQE--------IDPDAIK-----KELNEINVKLQDI 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 906 EGDVSLIRAKVAEELKKKpdAELKKKLELL--YQKWP---KALGAardrkdlvSKAGDLVKQFGDQVQALEQrlqgdqaE 980
Cdd:PRK01156 422 SSKVSSLNQRIRALRENL--DELSRNMEMLngQSVCPvcgTTLGE--------EKSNHIINHYNEKKSRLEE-------K 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 981 LDELLASDKAHDPEVCDALKLVELTMARrlaDVDALNAVMNRIESsapgpdanrLRRRADTLSDDAKGMAKKARTAADLA 1060
Cdd:PRK01156 485 IREIEIEVKDIDEKIVDLKKRKEYLESE---EINKSINEYNKIES---------ARADLEDIKIKINELKDKHDKYEEIK 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1061 QRKQGLakkfeRLCDEVSQFTENQKAEIQdaieKDLLNAERVQSKLNKIddfwSSNSRELKNVGDEIKIDaTPEDAQAVD 1140
Cdd:PRK01156 553 NRYKSL-----KLEDLDSKRTSWLNALAV----ISLIDIETNRSRSNEI----KKQLNDLESRLQEIEIG-FPDDKSYID 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1141 TKLAElqagIDGLLATLQEQNVHLEEKREQANRVQsesqkaaGKINSLVAEIADLDPIGRSRDELQKQKKEVVELAGDLG 1220
Cdd:PRK01156 619 KSIRE----IENEANNLNNKYNEIQENKILIEKLR-------GKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSR 687
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1143463347 1221 SAQTKMLELGAEWEAALgagivaqpvfEMNRAATDELNklaaragKRLAQREKKItETEDEIDKLHADADQIVGAL 1296
Cdd:PRK01156 688 KALDDAKANRARLESTI----------EILRTRINELS-------DRINDINETL-ESMKKIKKAIGDLKRLREAF 745
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
1865-2421 |
1.01e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.21 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1865 QRITNEEASANKVQFRNVAGEAKKVARQLGMEGNEANEKISDTVDEGKELVEEVMALCADRTETLEralALMEQLTSQFD 1944
Cdd:pfam12128 278 QEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAA---ADQEQLPSWQS 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1945 ELNKWLDQMDAELQASPSVTTATPAAELREMHDHNEELARMVAAYRPIIEGFKSDVGSLHEVLAEDQAPLLESVAGELVQ 2024
Cdd:pfam12128 355 ELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2025 GYEEVREAVRARGHAIDNMMGATIgfGERLETLVANLQGAADRLRENEGiSADPSVleSRLAENRSIVESLRDKQN---- 2100
Cdd:pfam12128 435 FNEEEYRLKSRLGELKLRLNQATA--TPELLLQLENFDERIERAREEQE-AANAEV--ERLQSELRQARKRRDQASealr 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2101 -AYDALKQTASELLASAPEGDAAAGDVENKLNRLEKLWKEIEREAVDRGVLLEDVLDKAkhFWSELDSCQKAVDDLRNRL 2179
Cdd:pfam12128 510 qASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPE--VWDGSVGGELNLYGVKLDL 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2180 ELVEpatgHPEQLADQQEI---MAQVASEMERARPRIEALSIAGKQLADYVpDDEKAVIENQVANVRGGFSTITGLFAEk 2256
Cdd:pfam12128 588 KRID----VPEWAASEEELrerLDKAEEALQSAREKQAAAEEQLVQANGEL-EKASREETFARTALKNARLDLRRLFDE- 661
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2257 KRDLIAAMEEAMTFHGDL-QELLKWLDmAEQKLLKMspvEHAKHMTEIEQLLKELHTFKDE-----VHERGVAKEQVVAT 2330
Cdd:pfam12128 662 KQSEKDKKNKALAERKDSaNERLNSLE-AQLKQLDK---KHQAWLEEQKEQKREARTEKQAywqvvEGALDAQLALLKAA 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2331 ALQLAADAPPHLAATVRQPVADLNTR------WSRLNAALAEREHKLENLmlqmGKLASTIAQLTAWMDKTRATLKdiap 2404
Cdd:pfam12128 738 IAARRSGAKAELKALETWYKRDLASLgvdpdvIAKLKREIRTLERKIERI----AVRRQEVLRYFDWYQETWLQRR---- 809
|
570
....*....|....*..
gi 1143463347 2405 PKNAVNLRDIEIAQCKL 2421
Cdd:pfam12128 810 PRLATQLSNIERAISEL 826
|
|
| AAA_13 |
pfam13166 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
729-1206 |
1.02e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.
Pssm-ID: 463796 [Multi-domain] Cd Length: 712 Bit Score: 45.05 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 729 ESGLDENaGRVEEAAKLGQELKDIQKELRKELGELesnvekasamssNDIGDQLATLDSLKSrfgGVDKALEKLKGILEA 808
Cdd:pfam13166 72 EENLSEQ-GEIKPIFTLGEESIEIQEKIAKLKKEI------------KDHEEKLDAAEANLQ---KLDKEKEKLEADFLD 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 809 TEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNegLELEKKLDELIGTVNsaENELELAAPIAAESLKL 888
Cdd:pfam13166 136 ECWKKIKRKKNSALSEALNGFKYEANFKSRLLREIEKDNFNAGV--LLSDEDRKAALATVF--SDNKPEIAPLTFNVIDF 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 889 aDELKRAEELFQKLIeneGDVSLIrakvaEELKKKPDAelkkklellyQKWPKA-LGAARDRKDL---------VSKAGD 958
Cdd:pfam13166 212 -DALEKAEILIQKVI---GKSSAI-----EELIKNPDL----------ADWVEQgLELHKAHLDTcpfcgqplpAERKAA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 959 LVKQFGDQVQALEQRLQGDQAELDELLASDKAhdpevcdalklveltmarRLADVDALNavmnrIESSAPGPDANRLRRR 1038
Cdd:pfam13166 273 LEAHFDDEFTEFQNRLQKLIEKVESAISSLLA------------------QLPAVSDLA-----SLLSAFELDVEDIESE 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1039 ADTLSDDAKGMAKKartaadLAQRKQGLAKKFE--RLCDEVSQFTENQkAEIQDAIEKdllNAERVQ---SKLNK-IDDF 1112
Cdd:pfam13166 330 AEVLNSQLDGLRRA------LEAKRKDPFKSIEldSVDAKIESINDLV-ASINELIAK---HNEITDnfeEEKNKaKKKL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1113 WSSNSRELKnvgdeIKIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNvhlEEKREQANRVQSEsQKAAGKINSLVAEi 1192
Cdd:pfam13166 400 RLHLVEEFK-----SEIDEYKDKYAGLEKAINSLEKEIKNLEAEIKKLR---EEIKELEAQLRDH-KPGADEINKLLKA- 469
|
490
....*....|....
gi 1143463347 1193 adldpIGRSRDELQ 1206
Cdd:pfam13166 470 -----FGFGELELS 478
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
357-904 |
1.66e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 357 PEAQSEVEALQDQADNLERITNNLCNIpnvtrtepviQKSKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLss 436
Cdd:COG4913 221 PDTFEAADALVEHFDDLERAHEALEDA----------REQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQR-- 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 437 FIGAFDDELKGLEKvsiDKEKLAEQRRQTQDLVDKHSEgnaILDDVEAiaqkvtaedpsktgsAQKSVGelGARLQRQAS 516
Cdd:COG4913 289 RLELLEAELEELRA---ELARLEAELERLEARLDALRE---ELDELEA---------------QIRGNG--GDRLEQLER 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 517 ELKARGDKINKLDSKATSFAESEAAVlgyiekqkdqlstGFPVPATKEGVKSQLLDLERMNKTGKEEQRRVDDARHSARE 596
Cdd:COG4913 346 EIERLERELEERERRRARLEALLAAL-------------GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 597 LAREA-----SVEKEVQDMNQReKKLLDEWedLADQFDAVRSRANKAE----------QVLNECAQ----MEKYIGAKKN 657
Cdd:COG4913 413 ALRDLrrelrELEAEIASLERR-KSNIPAR--LLALRDALAEALGLDEaelpfvgeliEVRPEEERwrgaIERVLGGFAL 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 658 MLegIGAPSTEPGVAKA-----NRAQIQSMKAETEGEKSALE--HVNSLANELIADGGA-------------------NV 711
Cdd:COG4913 490 TL--LVPPEHYAAALRWvnrlhLRGRLVYERVRTGLPDPERPrlDPDSLAGKLDFKPHPfrawleaelgrrfdyvcvdSP 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 712 EEL---------------------MKKMDRLNRKW----------HSLESGLDENAGRVEEAAKLGQELKDIQKELRK-- 758
Cdd:COG4913 568 EELrrhpraitragqvkgngtrheKDDRRRIRSRYvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDALQErr 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 759 -------ELGELESNVEKASAMSSnDIGDQLATLDSLKSRFGGVDKALEKLKGILEATEELevdatnRAEIQEQLETTQK 831
Cdd:COG4913 648 ealqrlaEYSWDEIDVASAEREIA-ELEAELERLDASSDDLAALEEQLEELEAELEELEEE------LDELKGEIGRLEK 720
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1143463347 832 KADELERKIENVKKAALNAQNEG-LELEKKLDELIGTVNSAENELELAAPIAAESLKLADELKRAEELFQKLIE 904
Cdd:COG4913 721 ELEQAEEELDELQDRLEAAEDLArLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMR 794
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
680-941 |
1.92e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.86 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 680 QSMKAETEGEKSALEHVNSLANELIADGGANVEELMK-KMDRLNRKWHslESGLDENAGRVEEAAKLGQELKDIQKELRK 758
Cdd:pfam05667 258 SAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGLtKGSRFTHTEK--LQFTNEAPAATSSPPTKVETEEELQQQREE 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 759 ELGELESNvekasamssndigdqlatLDSLKSRfggvdkaleklkgILEATEELEVDATNRAEIQEQLETTQKKADELER 838
Cdd:pfam05667 336 ELEELQEQ------------------LEDLESS-------------IQELEKEIKKLESSIKQVEEELEELKEQNEELEK 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 839 KIENVKKAA---LNAQNEGLELEKKLDEligtvnSAENELELA-------APIAAESLKLADEL-KRAEELFQKLIENEG 907
Cdd:pfam05667 385 QYKVKKKTLdllPDAEENIAKLQALVDA------SAQRLVELAgqwekhrVPLIEEYRALKEAKsNKEDESQRKLEEIKE 458
|
250 260 270
....*....|....*....|....*....|....
gi 1143463347 908 DVSLIRaKVAEELKKKpdAELKKKLELLYQKWPK 941
Cdd:pfam05667 459 LREKIK-EVAEEAKQK--EELYKQLVAEYERLPK 489
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
709-929 |
2.12e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 43.91 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 709 ANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRK------ELGELE------SNVEK------- 769
Cdd:COG0497 151 AGLEELLEEYREAYRAWRALKKELEELRADEAERARELDLLRFQLEELEAaalqpgEEEELEeerrrlSNAEKlrealqe 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 770 -ASAMSSNDIG--DQLATLDSLKSRFGGVDKALEKLKGILE-ATEELEvDATNR-AEIQEQLETTQKKADELERKIenvk 844
Cdd:COG0497 231 aLEALSGGEGGalDLLGQALRALERLAEYDPSLAELAERLEsALIELE-EAASElRRYLDSLEFDPERLEEVEERL---- 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 845 kAALNAqnegleLEKK----LDELIGTVNSAENELELAAPIAAESLKLADELKRAEELFQKLIEnegDVSLIRAKVAEEL 920
Cdd:COG0497 306 -ALLRR------LARKygvtVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELLEAAE---KLSAARKKAAKKL 375
|
....*....
gi 1143463347 921 KKKPDAELK 929
Cdd:COG0497 376 EKAVTAELA 384
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
1828-1930 |
2.32e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 40.01 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1828 LDDLQYLIEWFSAArERILEGAPPSLDLEVLKSQLKHQRITNEEASANKVQFRNVageaKKVARQLGMEGNEANEKISDT 1907
Cdd:smart00150 4 LRDADELEAWLEEK-EQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEAL----NELGEQLIEEGHPDAEEIEER 78
|
90 100
....*....|....*....|...
gi 1143463347 1908 VDEGKELVEEVMALCADRTETLE 1930
Cdd:smart00150 79 LEELNERWEELKELAEERRQKLE 101
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
111-841 |
2.38e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 2.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 111 LHAMNDEHSEQARRADEWLQmLQNDVEDVDQDPRFQRDEDRIQRIEELNRMAAGGSSQLDDAEQASRRLLTALEGTN--- 187
Cdd:TIGR00618 181 LALMEFAKKKSLHGKAELLT-LRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkkq 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 188 -VANDVRARHEELANL--RRGKHQKVIDRLSQNMMEAASRKAEAEGVKQAVENLRQWSEQTAQRTR---QPVQLPLTELD 261
Cdd:TIGR00618 260 qLLKQLRARIEELRAQeaVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKllmKRAAHVKQQSS 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 262 LHEARKDEQVLHGEiENRLALIEELEKKAADVGDHAsLAELQEckmklkrsnsdLKGLRDNIFDAINGLQTVNSEGETLS 341
Cdd:TIGR00618 340 IEEQRRLLQTLHSQ-EIHIRDAHEVATSIREISCQQ-HTLTQH-----------IHTLQQQKTTLTQKLQSLCKELDILQ 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 342 RAVDSAGAKIrSARLPEAQSEVEALQDQADNLERITNNLCNIPNVTRTEpvIQKSKDLRKrvdsCAQELDARMGKLAELE 421
Cdd:TIGR00618 407 REQATIDTRT-SAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCE--KLEKIHLQE----SAQSLKEREQQLQTKE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 422 SLDAEFDGAKnklsSFIGAFDDELKGLEKVSIDKEKLAEQRRQ-----------TQDLVDKHSEGNAILDDVEAIAQKVT 490
Cdd:TIGR00618 480 QIHLQETRKK----AVVLARLLELQEEPCPLCGSCIHPNPARQdidnpgpltrrMQRGEQTYAQLETSEEDVYHQLTSER 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 491 aedpsktgsaqKSVGELGARLQRQASELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQlstgfpvpatkegvKSQL 570
Cdd:TIGR00618 556 -----------KQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEA--------------EDML 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 571 LDLERMNKTGKEEQrrVDDARHSARELAREASVEKEVQDMNQREKKLLDEWEDLAdqfdAVRSRANKA---EQVLNECAQ 647
Cdd:TIGR00618 611 ACEQHALLRKLQPE--QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREH----ALSIRVLPKellASRQLALQK 684
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 648 MEKYIGAKKNMLEGIG----APSTEPGVAKANRAQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDrLNR 723
Cdd:TIGR00618 685 MQSEKEQLTYWKEMLAqcqtLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKART-EAH 763
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 724 KWHSLESGLDENAGrvEEAAKLGQELKDIQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKSRFGGVDKALEKLK 803
Cdd:TIGR00618 764 FNNNEEVTAALQTG--AELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841
|
730 740 750
....*....|....*....|....*....|....*....
gi 1143463347 804 GIL-EATEELEVDATNRAEiQEQLETTQKKADELERKIE 841
Cdd:TIGR00618 842 ATLgEITHQLLKYEECSKQ-LAQLTQEQAKIIQLSDKLN 879
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
723-1159 |
2.53e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 723 RKWHSLESGLDENAGRVEEAAKLGQELKDIQKE---LRKELGELESNVEKASAMSSNdiGDQLATLDSLKSRFGGVDKAL 799
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEEleeLEAELEELREELEKLEKLLQL--LPLYQELEALEAELAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 800 EKLKGILEATEELEVDatnRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLE-LEKKLDELIGTVNSAENELEla 878
Cdd:COG4717 149 EELEERLEELRELEEE---LEELEAELAELQEELEELLEQLSLATEEELQDLAEELEeLQQRLAELEEELEEAQEELE-- 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 879 apIAAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEELkkkpdaeLKKKLELLYQKWPKAL----GAARDRKDLVS 954
Cdd:COG4717 224 --ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLG-------LGGSLLSLILTIAGVLflvlGLLALLFLLLA 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 955 KAGDLVKQFGDQVQALEQRLQGDQAELDELLAsdKAHDPEVCDALKLVELtmARRLADVDALNAVMNRIESSApgpDANR 1034
Cdd:COG4717 295 REKASLGKEAEELQALPALEELEEEELEELLA--ALGLPPDLSPEELLEL--LDRIEELQELLREAEELEEEL---QLEE 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1035 LRRRADTLSDDAKGMAKKA-RTAADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDaiekdlLNAERVQSKLNKIDDFW 1113
Cdd:COG4717 368 LEQEIAALLAEAGVEDEEElRAALEQAEEYQELKEELEELEEQLEELLGELEELLEA------LDEEELEEELEELEEEL 441
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1143463347 1114 SSNSRELKNVGDEI-KIDATPEDAQAvDTKLAELQAGIDGLLATLQE 1159
Cdd:COG4717 442 EELEEELEELREELaELEAELEQLEE-DGELAELLQELEELKAELRE 487
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1137-1298 |
2.68e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.22 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1137 QAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKINSLVAEIADLD----------PIGRSRDELQ 1206
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEarikkyeeqlGNVRNNKEYE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1207 KQKKEVVELAGDLGSAQTKMLELGAEWEAALgagivaqpvfEMNRAATDELNKLAARAGKRLAQREKKITETEDEIDKLH 1286
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELE----------EELAELEAELAELEAELEEKKAELDEELAELEAELEELE 162
|
170
....*....|..
gi 1143463347 1287 ADADQIVGALEA 1298
Cdd:COG1579 163 AEREELAAKIPP 174
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
604-876 |
3.39e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.09 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 604 EKEVQDMNQREKKLLDEWEDLADQFDAVRSRANKAEQVLNECAQMEKYIGAKKNMLEgigapstepgvakanrAQIQSMK 683
Cdd:TIGR04523 369 QNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE----------------KEIERLK 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 684 AETEGEKSA---LEHVNSLANELIADGGANVEELMKKMDRLNRKWHSLESGLDEN----AGRVEEAAKLGQELKDI---Q 753
Cdd:TIGR04523 433 ETIIKNNSEikdLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKqkelKSKEKELKKLNEEKKELeekV 512
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 754 KELRKELGELESNVEKASAMSS------NDIGDQLATLDS------LKSRFGGVDKALEKLK----GILEATEELEVDA- 816
Cdd:TIGR04523 513 KDLTKKISSLKEKIEKLESEKKekeskiSDLEDELNKDDFelkkenLEKEIDEKNKEIEELKqtqkSLKKKQEEKQELId 592
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1143463347 817 ---TNRAEIQEQLETTQKKADELERKIENVKKaalnaQNEGLELEKKldeligTVNSAENELE 876
Cdd:TIGR04523 593 qkeKEKKDLIKEIEEKEKKISSLEKELEKAKK-----ENEKLSSIIK------NIKSKKNKLK 644
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1257-2042 |
3.45e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1257 LNKLAaRAGKRLAQREKKITETEDEIDKLHADADQIVGALEAIAKDEALQGApSQLLDPKQVSEKVRQLKESLKPVGEKM 1336
Cdd:TIGR02168 178 ERKLE-RTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELA-LLVLRLEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1337 DAFNTDckllIKTAGPESDTK-----ELDSLLKKVGDAYSDVVGKVSDKEMSVDAAVQQQGKVEDAYRALLNWLEETEEM 1411
Cdd:TIGR02168 256 EELTAE----LQELEEKLEELrlevsELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1412 MENRKKPSADAKVAKAQLhdyevlmkhvedkKPSVDGFKAMIEKivAEASSDEEKKALGNKNAQIE---DRYKDLLNSAV 1488
Cdd:TIGR02168 332 LDELAEELAELEEKLEEL-------------KEELESLEAELEE--LEAELEELESRLEELEEQLEtlrSKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1489 DRQRKLLDAVDLAERLQEVTIPLDSWLQSADKRLQALAKvpitvEKAEEMIGEQEALQDELEHKSDDLKDVLEIAPMlas 1568
Cdd:TIGR02168 397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL-----KELQAELEELEEELEELQEELERLEEALEELRE--- 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1569 lvSVEDANSISGQVNQLEARARALDAGITNMRPLLESFLQQIQDFTLDAEDMTQFVGE--TEVKLGELDELPIEP----- 1641
Cdd:TIGR02168 469 --ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVlsELISVDEGYEAAIEAalggr 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1642 -DDLVEQTNILAEIAVSIADRDEMMANIFEVGKQLAIQGEPEEALIAQKKLDDLKFRYADLMTSADE-KIAL-------- 1711
Cdd:TIGR02168 547 lQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlRKALsyllggvl 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1712 ----LAKAIPLSEGFHEGFDTV-----------MQVLEDMDRDLQTIdeedpETQAELiflleEDISQKMRPSVDELTAL 1776
Cdd:TIGR02168 627 vvddLDNALELAKKLRPGYRIVtldgdlvrpggVITGGSAKTNSSIL-----ERRREI-----EELEEKIEELEEKIAEL 696
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1777 SNQLQVLCSA-----DKADELQTNTIAMNKLVNSVADRVARRAERIEMASKQSRAVLDDLQYLIEWFSAARERILEGAPP 1851
Cdd:TIGR02168 697 EKALAELRKEleeleEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1852 SLDLEVLKSQLKHQRitnEEASANKVQFRNVAGEAKKVARQLGMEGNEANEKISD---TVDEGKELVEEVMALCADRTET 1928
Cdd:TIGR02168 777 LAEAEAEIEELEAQI---EQLKEELKALREALDELRAELTLLNEEAANLRERLESlerRIAATERRLEDLEEQIEELSED 853
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1929 LERALALMEQLTSQFDE----LNKWLDQMDAELQASPSVTTA--TPAAELREMHDHN-------EELARMVAAYRPIIEG 1995
Cdd:TIGR02168 854 IESLAAEIEELEELIEEleseLEALLNERASLEEALALLRSEleELSEELRELESKRselrrelEELREKLAQLELRLEG 933
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 1143463347 1996 FKSDVGSLHEVLAEDQAPLLEsVAGELVQGYEEVREAVRARGHAIDN 2042
Cdd:TIGR02168 934 LEVRIDNLQERLSEEYSLTLE-EAEALENKIEDDEEEARRRLKRLEN 979
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
994-1236 |
3.54e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 3.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 994 EVCDALKLVELTMARRLADVDALNAVMNRIESSAP-----------GPDANRLRRRADTLSD-------DAKgMAKKART 1055
Cdd:COG3206 98 RVVDKLNLDEDPLGEEASREAAIERLRKNLTVEPVkgsnvieisytSPDPELAAAVANALAEayleqnlELR-REEARKA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1056 AADLAQRKQGLAKKFERLCDEVSQFTENQKAEIQDAIEKDLLNA--------ERVQSKLNKIDDFWSSNSRELKNVGDEI 1127
Cdd:COG3206 177 LEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQlselesqlAEARAELAEAEARLAALRAQLGSGPDAL 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1128 KIDATPEDAQAVDTKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKI-NSLVAEIADLDpigRSRDELQ 1206
Cdd:COG3206 257 PELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIlASLEAELEALQ---AREASLQ 333
|
250 260 270
....*....|....*....|....*....|
gi 1143463347 1207 KQKKEVVELAGDLGSAQTKMLELGAEWEAA 1236
Cdd:COG3206 334 AQLAQLEARLAELPELEAELRRLEREVEVA 363
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1852-2620 |
3.60e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 3.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1852 SLDLEVLKSQLKHQRitnEEASANKVQFRNVAGEAKKVARQLgmegNEANEKISDTVDEGKELVEEVmalcADRTETLER 1931
Cdd:TIGR02168 224 ELELALLVLRLEELR---EELEELQEELKEAEEELEELTAEL----QELEEKLEELRLEVSELEEEI----EELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1932 ALALMEQLTSQFDELNKWLDQMDAELQASpsvttatpAAELREMHDHNEELARMVAAYRPIIEGFKSDVGSLHEVLAEdq 2011
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEEL--------EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE-- 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2012 aplLESVAGELVQGYEEVREAVRARGHAIDNMmgatigfGERLETLVANLQGAADRLrenegisadpSVLESRLAENRSI 2091
Cdd:TIGR02168 363 ---LEAELEELESRLEELEEQLETLRSKVAQL-------ELQIASLNNEIERLEARL----------ERLEDRRERLQQE 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2092 VESLRDKQNAYDaLKQTASELLASAPEGDAAAGDVENKLNRLEKLWKEIEReavdrgvlLEDVLDKAKHFWSELDSCQKA 2171
Cdd:TIGR02168 423 IEELLKKLEEAE-LKELQAELEELEEELEELQEELERLEEALEELREELEE--------AEQALDAAERELAQLQARLDS 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2172 VDDLRNRLElvEPATGHPEQLADQQEI--MAQVASEMERARPRIE-ALSIA-GKQLADYVPDDEKAVIENQ--VANVRGG 2245
Cdd:TIGR02168 494 LERLQENLE--GFSEGVKALLKNQSGLsgILGVLSELISVDEGYEaAIEAAlGGRLQAVVVENLNAAKKAIafLKQNELG 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2246 FSTITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLlkmSPVehakhmteIEQLLKELHTFKDevhergvake 2325
Cdd:TIGR02168 572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL---RKA--------LSYLLGGVLVVDD---------- 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2326 qvVATALQLAADAPPHLAATVRQPVAdLNTRWS------RLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATL 2399
Cdd:TIGR02168 631 --LDNALELAKKLRPGYRIVTLDGDL-VRPGGVitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2400 KDIAppknavnlRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTSGALDAETSDSLKSMNLKWEDIQKVLESLAf 2479
Cdd:TIGR02168 708 EELE--------EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELA- 778
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2480 dmeVAKKEAENVGGEVEKWQRWLEETESALLSTKptGGLPETAEFQLDEFKALKlDVEHNASPLEAHLHATEQHLKEEPQ 2559
Cdd:TIGR02168 779 ---EAEAEIEELEAQIEQLKEELKALREALDELR--AELTLLNEEAANLRERLE-SLERRIAATERRLEDLEEQIEELSE 852
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1143463347 2560 DAdTWLSKTHGAMKTKWNKVKELLVDREKKLQVAYEQAVALESALNDMEDWIIAAERKLTD 2620
Cdd:TIGR02168 853 DI-ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2065-2152 |
4.23e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 39.24 E-value: 4.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2065 ADRLRENEGISADPSVLESRLAENRSIVESLRDKQNAYDALKQTASELLASAPEgdaAAGDVENKLNRLEKLWKEIEREA 2144
Cdd:smart00150 17 KEQLLASEDLGKDLESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHP---DAEEIEERLEELNERWEELKELA 93
|
....*...
gi 1143463347 2145 VDRGVLLE 2152
Cdd:smart00150 94 EERRQKLE 101
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
712-1512 |
4.60e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.04 E-value: 4.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 712 EELMKK---MDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKEL-GELESNVEKASAMSSNDIGDQLATLDS 787
Cdd:pfam02463 176 KKLIEEtenLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLyLDYLKLNEERIDLLQELLRDEQEEIES 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 788 LKSRF-GGVDKALEKLKGILEATEELEVDATNRAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIG 866
Cdd:pfam02463 256 SKQEIeKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 867 TVNSAENELELAApIAAESLKLADELKRAEELFQKLIENEGDVSLIRAKVAEELKKKPDAELKKKLELLYQKWPKALGAA 946
Cdd:pfam02463 336 EIEELEKELKELE-IKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELA 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 947 RDRKDLVSKAGDLVKQFGDQVQALEQRLQGDQAELDELLASDKAHDPEVCDALK----------LVELTMARRLADVDAL 1016
Cdd:pfam02463 415 RQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKksedllketqLVKLQEQLELLLSRQK 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1017 NAVMNRIESSAPGPDANRLRRRADTLSDDAKG-----------------------MAKKARTAADLAQRKQGLAKKFERL 1073
Cdd:pfam02463 495 LEERSQKESKARSGLKVLLALIKDGVGGRIISahgrlgdlgvavenykvaistavIVEVSATADEVEERQKLVRALTELP 574
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1074 CDEVSQFTENQKAEIQDAIEKDLLNAERVQ--SKLNKIDDFWSSNSRELKNVGDEIKIDATPEDAQAV--------DTKL 1143
Cdd:pfam02463 575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKakesglrkGVSL 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1144 AELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKINSLVAEIADLDPIGRSR---DELQKQKKEVVELAGDLG 1220
Cdd:pfam02463 655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKklkLEAEELLADRVQEAQDKI 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1221 SAQTKMLELGAEWEAALGAGIVAQPVFEMNRAAtDELNKLAARAGKRLAQREKKITETEDEIDKLhadADQIVGALEAIA 1300
Cdd:pfam02463 735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKS-ELSLKEKELAEEREKTEKLKVEEEKEEKLKA---QEEELRALEEEL 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1301 KDEALQGAPSQLLDPKQVSEKVRQLKESLKPVGEKMDAFNtdcKLLIKTAGPESDTKELDSLLKKVGDAYSDVVGKVSDK 1380
Cdd:pfam02463 811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEK---LAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1381 EMSVDAAVQQQGKVEDAYRALLNWLEETEEMMENRKKPSADAKVakaQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEa 1460
Cdd:pfam02463 888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILL---KYEEEPEELLLEEADEKEKEENNKEEEEERNK- 963
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 1143463347 1461 SSDEEKKALGNKNAQIEDRYKDLLNSAVDRQRKLLDAVDLAERLQEVTIPLD 1512
Cdd:pfam02463 964 RLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEET 1015
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1807-2210 |
4.82e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 42.72 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1807 ADRVARRAERIEMASKQSRAVLDDLQY---LIEWFSAARERiLEGAPPSLDLEVLKSQLKHQRITN--EEASANKVQFRN 1881
Cdd:PRK02224 278 AEEVRDLRERLEELEEERDDLLAEAGLddaDAEAVEARREE-LEDRDEELRDRLEECRVAAQAHNEeaESLREDADDLEE 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1882 VAGEAKKVARQLGMEGNEANEKISD---TVDEGKELVEEVMALCADRTETLERALALMEQLTSQFDELNkwldQMDAELQ 1958
Cdd:PRK02224 357 RAEELREEAAELESELEEAREAVEDrreEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELR----EREAELE 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1959 aspsvttatpaAELREMHDHNEELARMVAAYRpIIEGFKSDVGSLHEVLAEDQAPLLESVAGELvqgyEEVREAVRARGH 2038
Cdd:PRK02224 433 -----------ATLRTARERVEEAEALLEAGK-CPECGQPVEGSPHVETIEEDRERVEELEAEL----EDLEEEVEEVEE 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2039 AIdnmmgatigfgERLETLVAnLQGAADRLRENEgisadpSVLESRLAENRSIVESLRDKQnayDALKQTASELLASAPE 2118
Cdd:PRK02224 497 RL-----------ERAEDLVE-AEDRIERLEERR------EDLEELIAERRETIEEKRERA---EELRERAAELEAEAEE 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2119 GDAAAGDVENKLNRLEKLWKEIEREavdRGVLLE--DVLDKAKHFWSELDSCQKAVDDLRNRLE-LVEPATGHPEQLADQ 2195
Cdd:PRK02224 556 KREAAAEAEEEAEEAREEVAELNSK---LAELKEriESLERIRTLLAAIADAEDEIERLREKREaLAELNDERRERLAEK 632
|
410
....*....|....*
gi 1143463347 2196 QEIMAQVASEMERAR 2210
Cdd:PRK02224 633 RERKRELEAEFDEAR 647
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
572-1372 |
5.53e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.75 E-value: 5.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 572 DLERMNKTGKEEQRRVDDARHSARELAREASVEKEVQDMNQREKK-----LLDEWEDLADQFDAVRSRANKAEQVLN--- 643
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEklt 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 644 -ECAQMEKYIGAKKNMLEGIGAPSTEPGVAKANraQIQSMKAETEGEKSALEHVNSLANELIADGGANVEELMKKMDRLN 722
Cdd:TIGR02169 258 eEISELEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 723 RKWHSLESGLDENAGRVEeaaKLGQELKDIQKELRKELGELESnVEKASAMSSNDIGDQLATLDSLKSRF----GGVDKA 798
Cdd:TIGR02169 336 AEIEELEREIEEERKRRD---KLTEEYAELKEELEDLRAELEE-VDKEFAETRDELKDYREKLEKLKREInelkRELDRL 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 799 LEKLKGILEATEELEVDATN----RAEIQEQLETTQKKADELERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENE 874
Cdd:TIGR02169 412 QEELQRLSEELADLNAAIAGieakINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 875 LELAAPIAAESLKLADELKRAEELFQKLIENegdvslIRAKVAEELKKKPdaELKKKLELlyqkwpkalgAARDRKDLVS 954
Cdd:TIGR02169 492 LAEAEAQARASEERVRGGRAVEEVLKASIQG------VHGTVAQLGSVGE--RYATAIEV----------AAGNRLNNVV 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 955 KAGDLVKQfgDQVQALEQRLQGDQAEL------DELLASDKAHDPEVCD-ALKLVELTMARRLADVDAL--NAVMNRIES 1025
Cdd:TIGR02169 554 VEDDAVAK--EAIELLKRRKAGRATFLplnkmrDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVFgdTLVVEDIEA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1026 SAPGPDANRLRRRADTLSDDAKGMAKKARTAADLAQRKQGLAKKFERLCDEVsqftenqkaeiqDAIEKDLlnaERVQSK 1105
Cdd:TIGR02169 632 ARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL------------EGLKREL---SSLQSE 696
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1106 LNKIDDFWSSNSRELKnvgdeikidatpeDAQAvdtKLAELQAGIDGLLATLQEQNVHLEEKREQANRVQSESQKAAGKI 1185
Cdd:TIGR02169 697 LRRIENRLDELSQELS-------------DASR---KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSEL 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1186 NSLVAEIADLD--------------------PIGRSRDELQKQKKEVVELAGDLGSAQTKM--LELGAEWEAALGAGIVA 1243
Cdd:TIGR02169 761 KELEARIEELEedlhkleealndlearlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLnrLTLEKEYLEKEIQELQE 840
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1244 QPVF-----EMNRAATDELNKLAARAGKRLAQREKKITETEDEIDKLHADADqivgalEAIAKDEALQGAPSQL-LDPKQ 1317
Cdd:TIGR02169 841 QRIDlkeqiKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD------ELEAQLRELERKIEELeAQIEK 914
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 1318 VSEKVRQLKESLKPVGEKMDAFNTDCKLLIKTAGPESDTKELDSLLKKVGDAYSD 1372
Cdd:TIGR02169 915 KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRA 969
|
|
| Spectrin |
pfam00435 |
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in ... |
1399-1496 |
5.89e-03 |
|
Spectrin repeat; Spectrin repeat-domains are found in several proteins involved in cytoskeletal structure. These include spectrin, alpha-actinin and dystrophin. The sequence repeat used in this family is taken from the structural repeat in reference. The spectrin domain- repeat forms a three helix bundle. The second helix is interrupted by proline in some sequences. The repeats are defined by a characteriztic tryptophan (W) residue at position 17 in helix A and a leucine (L) at 2 residues from the carboxyl end of helix C. Although the domain occurs in multiple repeats along sequences, the domains are actually stable on their own - ie they act, biophysically, like domains rather than repeats that along function when aggregated.
Pssm-ID: 395348 [Multi-domain] Cd Length: 105 Bit Score: 38.84 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1399 RALLNWLEETEEMMENRKKPSaDAKVAKAQLHDYEVLMKHVEDKKPSVDGFKAMIEKIVAEASSDEEkkALGNKNAQIED 1478
Cdd:pfam00435 11 DDLESWIEEKEALLSSEDYGK-DLESVQALLKKHKALEAELAAHQDRVEALNELAEKLIDEGHYASE--EIQERLEELNE 87
|
90
....*....|....*...
gi 1143463347 1479 RYKDLLNSAVDRQRKLLD 1496
Cdd:pfam00435 88 RWEQLLELAAERKQKLEE 105
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
140-844 |
5.94e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 42.52 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 140 DQDPRFQRDEDRIQRIEELNRMAAGGSSQLDDAEQASRRLLTaLEGTNVANDVR--ARHEELANLRRGKHQKVI---DRL 214
Cdd:pfam12128 221 QQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSH-LHFGYKSDETLiaSRQEERQETSAELNQLLRtldDQW 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 215 SQNMMEAASRKAEAEGvkqAVENLRQWSEQTAQRTRQPVQLPLTELDLHEARKDEqvLHGEIENRLALIEELEKKAADVg 294
Cdd:pfam12128 300 KEKRDELNGELSAADA---AVAKDRSELEALEDQHGAFLDADIETAAADQEQLPS--WQSELENLEERLKALTGKHQDV- 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 295 DHASLAELQECKMKLKRSNSDLKGLRDNIFDAINGLQTVnseGETLSRAVDSAGAKIRSARLPEAQSEVEALQDQADNLE 374
Cdd:pfam12128 374 TAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAV---AEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 375 RITNNlcnipnVTRTEPVIQKSKDLRKRVDSCAQELDARMGKLAELESLDAEFDGAKNKLSSFIGafDDELKGLEKVSID 454
Cdd:pfam12128 451 LRLNQ------ATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALR--QASRRLEERQSAL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 455 KEKLAEQRRQTQDLVdkHSEGNAILDDVEAIAQKVTAE-------DPSKTGSAQK---SVGELGARLQR--------QAS 516
Cdd:pfam12128 523 DELELQLFPQAGTLL--HFLRKEAPDWEQSIGKVISPEllhrtdlDPEVWDGSVGgelNLYGVKLDLKRidvpewaaSEE 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 517 ELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQLSTGFPVPATkeGVKSQLLDLERMNKTGKEEQRRVDDARHSare 596
Cdd:pfam12128 601 ELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFART--ALKNARLDLRRLFDEKQSEKDKKNKALAE--- 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 597 laREASVEKEVQDMNQREKKLLDEWEDLADQFDAVRSRANKAEQvlnecAQMEKYIGAKKNMLEGIGApstepgvakANR 676
Cdd:pfam12128 676 --RKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQ-----AYWQVVEGALDAQLALLKA---------AIA 739
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 677 AQIQSMKAETEGEKSalEHVNSLAN-----ELIADGGANVEELMKKMDRLNRKWHSL--------ESGLDENAGRVEEAA 743
Cdd:pfam12128 740 ARRSGAKAELKALET--WYKRDLASlgvdpDVIAKLKREIRTLERKIERIAVRRQEVlryfdwyqETWLQRRPRLATQLS 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 744 KLGQElkdiQKELRKELGELESNVEKASAMSSNDIGDQLATLDSLKSRFGGVDKALEKLKGILEA--TEELEVDATNRAE 821
Cdd:pfam12128 818 NIERA----ISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDanSEQAQGSIGERLA 893
|
730 740
....*....|....*....|....
gi 1143463347 822 IQEQLETTQKKADE-LERKIENVK 844
Cdd:pfam12128 894 QLEDLKLKRDYLSEsVKKYVEHFK 917
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2190-2927 |
6.02e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 6.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2190 EQLADQQEIMAQVASEMERARPRIEALSIAGKQLadyvpDDEKAVIENQVANVRGGFSTITGLFAEKKRDLIAAMEEAMT 2269
Cdd:TIGR02168 239 EELEELQEELKEAEEELEELTAELQELEEKLEEL-----RLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2270 FHGDLQELLKWLDMAEQKLLKMSpvEHAKHMTEIEQLLKELHTFKDEVHERGVAKEQVVATALQlaadapphlaatvrqp 2349
Cdd:TIGR02168 314 LERQLEELEAQLEELESKLDELA--EELAELEEKLEELKEELESLEAELEELEAELEELESRLE---------------- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2350 vaDLNTRWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKNAVNLRDIEIAQCKLVVLSNDIH 2429
Cdd:TIGR02168 376 --ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2430 AHQDSVNAVNRAAQKYIQTSGALDAETSDSLKSMNLKWEDIQKVLESLAFDMEVAK---KEAENVGGEV----------E 2496
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKallKNQSGLSGILgvlselisvdE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2497 KWQRWLEetesALLSTKPTGGLPETAEFQLDEFKALKLDVEHNASPLEAhlhateqhlkeePQDADTWLSKTHGAMKTKW 2576
Cdd:TIGR02168 534 GYEAAIE----AALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPL------------DSIKGTEIQGNDREILKNI 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2577 NKVKELLVDREK---KLQVA-------------YEQAVALESALNDMEDWIIAAERKLTDQPSISRLPDVIEKQLAEHES 2640
Cdd:TIGR02168 598 EGFLGVAKDLVKfdpKLRKAlsyllggvlvvddLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRR 677
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2641 WMEEVAgRKMAMTKHQASGVHMQYYCEKKDAIPIKNRLVSLKHRVEKISGRTAERAKQLAVTRDEVATWQDGLHDLEHFI 2720
Cdd:TIGR02168 678 EIEELE-EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2721 SDVLVKIAP-EPNTTSSLEKLKAKLEEVKEAQRDVTAKQTLFDVTRKRGIGL--AERATRSEYKQISMTNEKMSKKWAEM 2797
Cdd:TIGR02168 757 TELEAEIEElEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELraELTLLNEEAANLRERLESLERRIAAT 836
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2798 LKKLRDRLREAEQAVLEGGAFEESMNDLESWVDDELERYQKAEHEpVFADIDGVRALVDEESRRSAERKTKENGVKTVVK 2877
Cdd:TIGR02168 837 ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE-RASLEEALALLRSELEELSEELRELESKRSELRR 915
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*..
gi 1143463347 2878 KADALMASGVDEKDSIAQAK-------ERLVEKWNQVEEAARHRGNSIKEAEQAAEE 2927
Cdd:TIGR02168 916 ELEELREKLAQLELRLEGLEvridnlqERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1056-1232 |
6.26e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 6.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1056 AADLAQRKQglaKKFERLCDEVSQFtENQKAEIQDAIEKDLLNAERVQSKLNKIDDFWSSNSRELKNVGDEIK------- 1128
Cdd:PHA02562 211 NGENIARKQ---NKYDELVEEAKTI-KAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKmyekggv 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1129 -------IDATPEDAQAVDTKLAELQAGIDgllatlqeqnvHLEEKREQANRVQSESQKAAGKINSLVAEIADLD-PIGR 1200
Cdd:PHA02562 287 cptctqqISEGPDRITKIKDKLKELQHSLE-----------KLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKqSLIT 355
|
170 180 190
....*....|....*....|....*....|..
gi 1143463347 1201 SRDELQKQKKEVVELAGDLGSAQTKMLELGAE 1232
Cdd:PHA02562 356 LVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2737-3049 |
7.12e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 7.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2737 LEKLKAKLEEVkEAQRDVTAKQtlfdvtrkrgiglAERATRseYKQISmtnEKMSKKWAEmLKKLRDRLREAEQAVLEgg 2816
Cdd:COG1196 188 LERLEDILGEL-ERQLEPLERQ-------------AEKAER--YRELK---EELKELEAE-LLLLKLRELEAELEELE-- 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2817 afeESMNDLESWVDDELERYQKAEhepvfADIDGVRALVDEESRRSAERKTKENGVKTVVKKADALMASGVDEKDSIAQA 2896
Cdd:COG1196 246 ---AELEELEAELEELEAELAELE-----AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2897 KERLVEKWNQVEEAARHRGNSIKEAEQAAEEFDAKTHALLDWLAVEEQKLKASgLDEVEGVKQEMDEAKGRYQECLKKGE 2976
Cdd:COG1196 318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA-EAELAEAEEELEELAEELLEALRAAA 396
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1143463347 2977 EILSKCQPAAEPILRNwmrvvEARWKEVSEKVDEREFTLLEQEQKAKEQNEQIEKLAKFAAQKREELNRMIEQ 3049
Cdd:COG1196 397 ELAAQLEELEEAEEAL-----LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1855-2639 |
7.43e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.35 E-value: 7.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1855 LEVLKSQLKHQRITNEEAsankVQFRNVAGEAKKVARQL-GMEGNEANEKISDTVDEGKELVEEVMALcadrTETLERAL 1933
Cdd:TIGR02168 195 LNELERQLKSLERQAEKA----ERYKELKAELRELELALlVLRLEELREELEELQEELKEAEEELEEL----TAELQELE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1934 ALMEQLTSQFDELNKWLDQMDAELQ--------------------ASPSVTTATPAAELREMHDHNEELARMVAAYRPII 1993
Cdd:TIGR02168 267 EKLEELRLEVSELEEEIEELQKELYalaneisrleqqkqilrerlANLERQLEELEAQLEELESKLDELAEELAELEEKL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 1994 EGFKSDVGSLHEVLAEdqaplLESVAGELVQGYEEVREAVRARGHAIDNMmgatigfGERLETLVANLQGAADRLreneg 2073
Cdd:TIGR02168 347 EELKEELESLEAELEE-----LEAELEELESRLEELEEQLETLRSKVAQL-------ELQIASLNNEIERLEARL----- 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2074 isadpSVLESRLAENRSIVESLRDKQNAYDaLKQTASELLASAPEGDAAAGDVENKLNRLEKLWKEIEReavdrgvlLED 2153
Cdd:TIGR02168 410 -----ERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEELQEELERLEEALEELREELEE--------AEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2154 VLDKAKHFWSELDSCQKAVDDLRNRLElvEPATGHPEQLADQQEI--MAQVASEMERARPRIE-ALSIA-GKQLADYVPD 2229
Cdd:TIGR02168 476 ALDAAERELAQLQARLDSLERLQENLE--GFSEGVKALLKNQSGLsgILGVLSELISVDEGYEaAIEAAlGGRLQAVVVE 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2230 DEKAVIENQ--VANVRGGFSTITGLFAEKKRDLIAAMEEAMTFHGDLQELLKWLDMAEQKLLK--------MSPVEHAKH 2299
Cdd:TIGR02168 554 NLNAAKKAIafLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggVLVVDDLDN 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2300 MTEIEQLLKELHTF----KDEVHERGVAK--------------------EQVVATALQLAADAPPHLAAtVRQPVADLNT 2355
Cdd:TIGR02168 634 ALELAKKLRPGYRIvtldGDLVRPGGVITggsaktnssilerrreieelEEKIEELEEKIAELEKALAE-LRKELEELEE 712
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2356 RWSRLNAALAEREHKLENLMLQMGKLASTIAQLTAWMDKTRATLKDIAPPKnAVNLRDIEIAQCKLVVLSNDIHAHQDSV 2435
Cdd:TIGR02168 713 ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI-EELEERLEEAEEELAEAEAEIEELEAQI 791
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2436 NAVNRAAQKYIQTSGALDAEtsdsLKSMNLKWEDIQKVLESLAFDMEVAKKEAENVggeVEKWQRWLEETESALLSTKPT 2515
Cdd:TIGR02168 792 EQLKEELKALREALDELRAE----LTLLNEEAANLRERLESLERRIAATERRLEDL---EEQIEELSEDIESLAAEIEEL 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2516 GGLPETAEFQLDEFKALKLDVEHNASPLEAHLHATEQHLKEepqdadtwLSKTHGAMKTKWNKVKELLVDREKKLQVAYE 2595
Cdd:TIGR02168 865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRE--------LESKRSELRRELEELREKLAQLELRLEGLEV 936
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 1143463347 2596 QAVALESALNdmEDWIIAAERKLTDQPSISRLPDVIEKQLAEHE 2639
Cdd:TIGR02168 937 RIDNLQERLS--EEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
692-910 |
7.75e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 7.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 692 ALEHVNSLANELIADGGANVEELMKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQELKDIQKELRKELGELESNVEKAS 771
Cdd:COG3883 6 LAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 772 A----------MSSNDIGDQLATLDS-----LKSRFGGVDKALEKLKGILEATEELEVDATN-RAEIQEQLETTQKKADE 835
Cdd:COG3883 86 EelgeraralyRSGGSVSYLDVLLGSesfsdFLDRLSALSKIADADADLLEELKADKAELEAkKAELEAKLAELEALKAE 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1143463347 836 LERKIENVKKAALNAQNEGLELEKKLDELIGTVNSAENELELAAPIAAESLKLADELKRAEELFQKLIENEGDVS 910
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 240
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
509-793 |
7.95e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 7.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 509 ARLQRQASELKARGDKINKLDSKATSFAESEAAVLGYIEKQKDQLSTGfpvpATKEGVKSQLLDLERMNKTGKEEQRRVD 588
Cdd:COG4913 620 AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAE----REIAELEAELERLDASSDDLAALEEQLE 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 589 DARHSARELareasvEKEVQDMNQREKKLLDEWEDLADQFDAVRSRANKAEQvlNECAQMEKYIGAkknMLEGIGAPSTE 668
Cdd:COG4913 696 ELEAELEEL------EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAED--LARLELRALLEE---RFAAALGDAVE 764
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 669 PGVAKANRAQIQSMKAETEGEKSALEhvnslaneliadgganveelmKKMDRLNRKWHSLESGLDENAGRVEEAAKLGQE 748
Cdd:COG4913 765 RELRENLEERIDALRARLNRAEEELE---------------------RAMRAFNREWPAETADLDADLESLPEYLALLDR 823
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 749 LKDIQ--------KELRKE-----LGELESNVEKAsamsSNDIGDQLATL-DSLK-SRFG 793
Cdd:COG4913 824 LEEDGlpeyeerfKELLNEnsiefVADLLSKLRRA----IREIKERIDPLnDSLKrIPFG 879
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2926-3015 |
8.05e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 38.46 E-value: 8.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2926 EEFDAKTHALLDWLAVEEQKLKASG-----------LDEVEGVKQEMDEAKGRYQECLKKGEEILSKCQPAAEPIlRNWM 2994
Cdd:smart00150 1 QQFLRDADELEAWLEEKEQLLASEDlgkdlesvealLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEI-EERL 79
|
90 100
....*....|....*....|.
gi 1143463347 2995 RVVEARWKEVSEKVDEREFTL 3015
Cdd:smart00150 80 EELNERWEELKELAEERRQKL 100
|
|
| SPEC |
smart00150 |
Spectrin repeats; |
2380-2475 |
8.62e-03 |
|
Spectrin repeats;
Pssm-ID: 197544 [Multi-domain] Cd Length: 101 Bit Score: 38.46 E-value: 8.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 2380 KLASTIAQLTAWMDKTRATLKDIAPPKNavnLRDIEIAQCKLVVLSNDIHAHQDSVNAVNRAAQKYIQTSGALDAETSDS 2459
Cdd:smart00150 2 QFLRDADELEAWLEEKEQLLASEDLGKD---LESVEALLKKHEAFEAELEAHEERVEALNELGEQLIEEGHPDAEEIEER 78
|
90
....*....|....*.
gi 1143463347 2460 LKSMNLKWEDIQKVLE 2475
Cdd:smart00150 79 LEELNERWEELKELAE 94
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
259-476 |
8.87e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 8.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 259 ELDLHEARKDEQVLHGE---IENRLALIEELEKKAADVGDHAS----LAELQECKMKLKRSNSDLKGLRDNIFDAINGLQ 331
Cdd:COG4913 623 EEELAEAEERLEALEAEldaLQERREALQRLAEYSWDEIDVASaereIAELEAELERLDASSDDLAALEEQLEELEAELE 702
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143463347 332 TVNSEGETLSRAVDSAGAKIRsarlpEAQSEVEALQDQADNLERITNNLCN------IPNVTRTEPVIQKSKDLRKRVDS 405
Cdd:COG4913 703 ELEEELDELKGEIGRLEKELE-----QAEEELDELQDRLEAAEDLARLELRalleerFAAALGDAVERELRENLEERIDA 777
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1143463347 406 CAQELDARMGKLAEL-ESLDAEFDGAKNKLSSFIGAFDDELKGLEKvsIDKEKLAEQRRQTQDLVDKHSEGN 476
Cdd:COG4913 778 LRARLNRAEEELERAmRAFNREWPAETADLDADLESLPEYLALLDR--LEEDGLPEYEERFKELLNENSIEF 847
|
|
| |
