poly(A) RNA polymerase GLD2 isoform 4 [Homo sapiens]
nucleotidyltransferase domain-containing protein( domain architecture ID 1001423)
nucleotidyltransferase domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
TRF4 super family | cl34961 | DNA polymerase sigma [Replication, recombination and repair]; |
4-245 | 5.28e-30 | |||||
DNA polymerase sigma [Replication, recombination and repair]; The actual alignment was detected with superfamily member COG5260: Pssm-ID: 227585 [Multi-domain] Cd Length: 482 Bit Score: 116.80 E-value: 5.28e-30
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Name | Accession | Description | Interval | E-value | |||||
TRF4 | COG5260 | DNA polymerase sigma [Replication, recombination and repair]; |
4-245 | 5.28e-30 | |||||
DNA polymerase sigma [Replication, recombination and repair]; Pssm-ID: 227585 [Multi-domain] Cd Length: 482 Bit Score: 116.80 E-value: 5.28e-30
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NT_PAP_TUTase | cd05402 | Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; ... |
7-75 | 1.03e-15 | |||||
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; Poly(A) polymerases (PAPs) catalyze mRNA poly(A) tail synthesis, and terminal uridylyl transferases (TUTases) uridylate RNA. PAPs in this subgroup include human PAP alpha, mouse testis-specific cytoplasmic PAP beta, human nuclear PAP gamma, Saccharomyces cerevisiae PAP1, TRF4 and-5, Schizosaccharomyces pombe caffeine-induced death proteins -1, and -14, Caenorhabditis elegans Germ Line Development-2, and Chlamydomonas reinhardtii MUT68. This family also includes human U6 snRNA-specific TUTase1, and Trypanosoma brucei 3'-TUTase-1,-2, and 4. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. For the majority of proteins in this family, these carboxylate residues are conserved. Pssm-ID: 143392 [Multi-domain] Cd Length: 114 Bit Score: 71.05 E-value: 1.03e-15
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PAP_assoc | pfam03828 | Cid1 family poly A polymerase; This domain is found in poly(A) polymerases and has been shown ... |
163-217 | 1.21e-14 | |||||
Cid1 family poly A polymerase; This domain is found in poly(A) polymerases and has been shown to have polynucleotide adenylyltransferase activity. Proteins in this family have been located to both the nucleus and the cytoplasm. Pssm-ID: 427532 Cd Length: 60 Bit Score: 66.44 E-value: 1.21e-14
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Name | Accession | Description | Interval | E-value | |||||
TRF4 | COG5260 | DNA polymerase sigma [Replication, recombination and repair]; |
4-245 | 5.28e-30 | |||||
DNA polymerase sigma [Replication, recombination and repair]; Pssm-ID: 227585 [Multi-domain] Cd Length: 482 Bit Score: 116.80 E-value: 5.28e-30
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NT_PAP_TUTase | cd05402 | Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; ... |
7-75 | 1.03e-15 | |||||
Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases; Poly(A) polymerases (PAPs) catalyze mRNA poly(A) tail synthesis, and terminal uridylyl transferases (TUTases) uridylate RNA. PAPs in this subgroup include human PAP alpha, mouse testis-specific cytoplasmic PAP beta, human nuclear PAP gamma, Saccharomyces cerevisiae PAP1, TRF4 and-5, Schizosaccharomyces pombe caffeine-induced death proteins -1, and -14, Caenorhabditis elegans Germ Line Development-2, and Chlamydomonas reinhardtii MUT68. This family also includes human U6 snRNA-specific TUTase1, and Trypanosoma brucei 3'-TUTase-1,-2, and 4. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. For the majority of proteins in this family, these carboxylate residues are conserved. Pssm-ID: 143392 [Multi-domain] Cd Length: 114 Bit Score: 71.05 E-value: 1.03e-15
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PAP_assoc | pfam03828 | Cid1 family poly A polymerase; This domain is found in poly(A) polymerases and has been shown ... |
163-217 | 1.21e-14 | |||||
Cid1 family poly A polymerase; This domain is found in poly(A) polymerases and has been shown to have polynucleotide adenylyltransferase activity. Proteins in this family have been located to both the nucleus and the cytoplasm. Pssm-ID: 427532 Cd Length: 60 Bit Score: 66.44 E-value: 1.21e-14
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Blast search parameters | ||||
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