|
Name |
Accession |
Description |
Interval |
E-value |
| CCCAP |
pfam15964 |
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ... |
6-738 |
0e+00 |
|
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.
Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 896.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 6 ENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQA 85
Cdd:pfam15964 1 GNSTLEESLGQYQRSLRERANRSIHQLKCALHESDSTISEDEQEESLSSVVQNEDSGSPWSELQHSHAVNQLKALLQQQT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 86 DKESEVSPsRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLK 165
Cdd:pfam15964 81 KKENELSP-RRRKLSPSRTSEDESSSLPTVHDLVPIINDQSQYIHHLEAEVKFCKEELSEMKQRVQVVVLENEKLQQELK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 166 SQRQEETLREQTLLDASGNMHNSWItTGEDSGVGETSKRPFSHDNADFGKAASAGE----QLELnfliisnkksgrikqy 241
Cdd:pfam15964 160 SQTQEETLREQTLLDSSGNMQNSWC-TPEDSRVHQTSKRPASHNLAERLKSATTGEdekwRLEL---------------- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 242 lhsppcqplmtslqlsEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQH 321
Cdd:pfam15964 223 ----------------EKLKLLYEAKTEVLESQVKSLRKDLAESQKTCEDLKERLKHKESLVAASTSSRVGGLCLKCAQH 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 322 EAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELE 401
Cdd:pfam15964 287 EAVLAQTHTNVHMQTIERLTKERDDLMSALVSVRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELE 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 402 RQAERLEKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMD 481
Cdd:pfam15964 367 RQKERLEKELASQQEKRAQEKEALRKEMKKEREELGATMLALSQNVAQLEAQVEKVTREKNSLVSQLEEAQKQLASQEMD 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 482 VTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLG 561
Cdd:pfam15964 447 VTKVCGEMRYQLNQTKMKKDEAEKEHREYRTKTGRQLEIKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLTELLG 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 562 ESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKK 641
Cdd:pfam15964 527 ESEHQLHLTRLEKESIQQSFSNEAKAQALQAQQREQELTQKMQQMEAQHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKK 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 642 LEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLL 721
Cdd:pfam15964 607 LEEITQKSRSEVEQLSQEKEYLQDRLEKLQKRNEELEEQCVQHGRMHERMKQRLRQLDKHCQATAQQLVQLLSKQNQLFK 686
|
730
....*....|....*..
gi 1176461394 722 ERQSLSEEVDRLRTQLP 738
Cdd:pfam15964 687 ERQNLTEEVQSLRSQVP 703
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
429-737 |
6.85e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.77 E-value: 6.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 429 ITKEREYMGSKMLILSQNIAQLEAQVEKVT---KEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEK 505
Cdd:TIGR02168 661 ITGGSAKTNSSILERRREIEELEEKIEELEekiAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 506 EHREFRAKTNR----------DLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKD 575
Cdd:TIGR02168 741 EVEQLEERIAQlskelteleaEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAA 820
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 576 SiQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEqyllLTSQNTFLTKLKEECCTLAKKLEQISQ---KTRSE 652
Cdd:TIGR02168 821 N-LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE----IEELEELIEELESELEALLNERASLEEalaLLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 653 IAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLdkHSQATAQQLVQL---LSKQNQLLLERQSLSEE 729
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLeeaEALENKIEDDEEEARRR 973
|
....*...
gi 1176461394 730 VDRLRTQL 737
Cdd:TIGR02168 974 LKRLENKI 981
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
397-725 |
1.14e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.88 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 397 RKELERQAERLEK--ELASQQEKRAIE--------KDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN 466
Cdd:COG1196 202 LEPLERQAEKAERyrELKEELKELEAEllllklreLEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 467 QLEEIQSQLASREMDVtkvcgemryqlnktnmEKDEAEKEHREFRAKTNRdleikdQEIEKLRIELDESKQHLEQEQQKA 546
Cdd:COG1196 282 ELEEAQAEEYELLAEL----------------ARLEQDIARLEERRRELE------ERLEELEEELAELEEELEELEEEL 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 547 ALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTsqnt 626
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER---- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 627 fLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATA 706
Cdd:COG1196 416 -LERLEEELEELEEALAELEEEEEEEEEALEEAAE----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
|
330
....*....|....*....
gi 1176461394 707 QQLVQLLSKQNQLLLERQS 725
Cdd:COG1196 491 ARLLLLLEAEADYEGFLEG 509
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
390-735 |
5.30e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.69 E-value: 5.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 390 LIQCDQLRKELERQAERLEKElaSQQEKRAIEKDMMKKEITKEreymgskmlILSQNIAQLEAQVEKVTKEKISAINQLE 469
Cdd:TIGR02168 188 LDRLEDILNELERQLKSLERQ--AEKAERYKELKAELRELELA---------LLVLRLEELREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 470 EIQSQLASREMDVTkvcgEMRYQLNKTNMEKDEAEKEHREFRAKTNRdleiKDQEIEklriELDESKQHLEQEQQKAALA 549
Cdd:TIGR02168 257 ELTAELQELEEKLE----ELRLEVSELEEEIEELQKELYALANEISR----LEQQKQ----ILRERLANLERQLEELEAQ 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 550 REECLRLTELLGESEHQLhltRQEKDSIQQSFsKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNtflt 629
Cdd:TIGR02168 325 LEELESKLDELAEELAEL---EEKLEELKEEL-ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA---- 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 630 KLKEECCTLAKKLEQIS---QKTRSEIAQLSQEKRYTydKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATA 706
Cdd:TIGR02168 397 SLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
|
330 340
....*....|....*....|....*....
gi 1176461394 707 QQLVQLLSKQNQLLLERQSLSEEVDRLRT 735
Cdd:TIGR02168 475 QALDAAERELAQLQARLDSLERLQENLEG 503
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
443-737 |
6.16e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.57 E-value: 6.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 443 LSQNIAQLEAQVEKVTK-EKISAinQLEEIQSQLASREMDvtkvcgEMRYQLNKTNMEKDEAEKEHREFRAKtnrdLEIK 521
Cdd:COG1196 198 LERQLEPLERQAEKAERyRELKE--ELKELEAELLLLKLR------ELEAELEELEAELEELEAELEELEAE----LAEL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 522 DQEIEKLRIELDESKQHLEQEQQKAALAREEclrltelLGESEHQLHLTRQEKDSIQQsfskeakaqalqaqqREQELTQ 601
Cdd:COG1196 266 EAELEELRLELEELELELEEAQAEEYELLAE-------LARLEQDIARLEERRRELEE---------------RLEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 602 KIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRyTYDKLGKLQRRNEELEEQC 681
Cdd:COG1196 324 ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE-LAEELLEALRAAAELAAQL 402
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1176461394 682 VQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 737
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
395-728 |
3.99e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 3.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 395 QLRKeLERQAERLEKELASQQEKRAIEKDMMKKEITKEREymgsKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQ 474
Cdd:TIGR02168 201 QLKS-LERQAEKAERYKELKAELRELELALLVLRLEELRE----ELEELQEELKEAEEELEELTAELQELEEKLEELRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 475 LASREMDVTKVCGEMrYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECL 554
Cdd:TIGR02168 276 VSELEEEIEELQKEL-YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 555 RLTELLGESEHQ---LHLTRQEKDSIQQSFSK---EAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTS-QNTF 627
Cdd:TIGR02168 355 SLEAELEELEAEleeLESRLEELEEQLETLRSkvaQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 628 LTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKrytyDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQAtaq 707
Cdd:TIGR02168 435 LKELQAELEELEEELEELQEELERLEEALEELR----EELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG--- 507
|
330 340
....*....|....*....|.
gi 1176461394 708 qLVQLLSKQNQLLLERQSLSE 728
Cdd:TIGR02168 508 -VKALLKNQSGLSGILGVLSE 527
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
370-702 |
4.42e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.99 E-value: 4.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 370 EQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELAsQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQ 449
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE-ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 450 LEAQVEKVTKEKISAINQLEEIQSQLASREMDVTkvcgEMRYQLNKTNMEKDEAEKEH---REFRAKTNRDLEIKDQEIE 526
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIE----QLKEELKALREALDELRAELtllNEEAANLRERLESLERRIA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 527 KLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQsfskeakaQALQAQQREQELTQKIQQM 606
Cdd:TIGR02168 835 ATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--------ALALLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 607 EAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGR 686
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986
|
330 340
....*....|....*....|...
gi 1176461394 687 VH-------ETMKQRLRQLDKHS 702
Cdd:TIGR02168 987 VNlaaieeyEELKERYDFLTAQK 1009
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
341-680 |
4.49e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.00 E-value: 4.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 341 VKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANF-EKTKALiqcdqlrKELERQAERLEKELASQQEKra 419
Cdd:TIGR02169 182 VEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGyELLKEK-------EALERQKEAIERQLASLEEE-- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 420 iekdmmKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN-QLEEIQSQLASREMDVTKVCGEMR---YQLNK 495
Cdd:TIGR02169 253 ------LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKeKIGELEAEIASLERSIAEKERELEdaeERLAK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 496 TNMEKDEAEKEHREFRAKTNRDLEIKDQ---EIEKLRIELDESKQHLEQEQQKAALAREEclrltelLGESEHQLHLTRQ 572
Cdd:TIGR02169 327 LEAEIDKLLAEIEELEREIEEERKRRDKlteEYAELKEELEDLRAELEEVDKEFAETRDE-------LKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 573 EKDSIQQSFSKEAKAQALQAQQREqELTQKIQQMEAQHDKTENEqyllltsqntfLTKLKEECCTLAKKLEQISQ---KT 649
Cdd:TIGR02169 400 EINELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEE-----------KEDKALEIKKQEWKLEQLAAdlsKY 467
|
330 340 350
....*....|....*....|....*....|.
gi 1176461394 650 RSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 680
Cdd:TIGR02169 468 EQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
265-577 |
1.41e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.06 E-value: 1.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 265 EEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAAntcnrvgglclkcAQHEAVLSQTHTNVHMQTIERLVKER 344
Cdd:TIGR02168 683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-------------LSRQISALRKDLARLEAEVEQLEERI 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 345 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRK---ELERQAERLEKELASQQ------ 415
Cdd:TIGR02168 750 AQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRerlesl 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 416 EKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTkvcgEMRYQLNK 495
Cdd:TIGR02168 830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE----ELSEELRE 905
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 496 TNMEKDEAEKEHREFRAKtnrdLEIKDQEIEKLRIELDESKQHL-EQEQQKAALAREECLRLTELLGESEHQLHLTRQEK 574
Cdd:TIGR02168 906 LESKRSELRRELEELREK----LAQLELRLEGLEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981
|
...
gi 1176461394 575 DSI 577
Cdd:TIGR02168 982 KEL 984
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
291-598 |
2.34e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.56 E-value: 2.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 291 DLKEQLKHKEFLLAANTcnrvgglcLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASA-- 368
Cdd:COG1196 217 ELKEELKELEAELLLLK--------LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqa 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 369 --YEQVKQVLQISEEANFEKTK---ALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKEreymgskmlil 443
Cdd:COG1196 289 eeYELLAELARLEQDIARLEERrreLEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE----------- 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 444 sQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDvtkvcgemRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQ 523
Cdd:COG1196 358 -AELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--------AAELAAQLEELEEAEEALLERLERLEEELEELEE 428
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1176461394 524 EIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQE 598
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
335-679 |
2.00e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 335 QTIERLVKERDDLMsalvsvRSSLADTQQREASAYEQVKQVlqisEEANFEKTKALIQCDQLRKELE---RQAERLEKEL 411
Cdd:TIGR02169 198 QQLERLRREREKAE------RYQALLKEKREYEGYELLKEK----EALERQKEAIERQLASLEEELEkltEEISELEKRL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 412 ASQQEKRaiekdmmkKEITKEREYMGS-KMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMdvtkvcgemr 490
Cdd:TIGR02169 268 EEIEQLL--------EELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA---------- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 491 yQLNKTNMEKDEAEKEHREFRaktnRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREEclrltelLGESEHQLHLT 570
Cdd:TIGR02169 330 -EIDKLLAEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE-------LKDYREKLEKL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 571 RQEKDSIQQSFSKeakaqalqAQQREQELTQKIQQMEAQHDKTENEqyllltsqntfLTKLKEECCTLAKKLEQISQKTR 650
Cdd:TIGR02169 398 KREINELKRELDR--------LQEELQRLSEELADLNAAIAGIEAK-----------INELEEEKEDKALEIKKQEWKLE 458
|
330 340
....*....|....*....|....*....
gi 1176461394 651 SEIAQLSQEKRYTYDKLGKLQRRNEELEE 679
Cdd:TIGR02169 459 QLAADLSKYEQELYDLKEEYDRVEKELSK 487
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
443-680 |
2.47e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.53 E-value: 2.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 443 LSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMdvtkvcgemryQLNKTNMEkdeaekehrefRAKTNRDLEIKD 522
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-----------RIRALEQE-----------LAALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 523 QEIEKLRIELDESKQHLEQeqQKAALAREECLRLTELLGESEHQLHLTRQEKdsIQQSFSKEAKAQALQAQQREQELTQK 602
Cdd:COG4942 90 KEIAELRAELEAQKEELAE--LLRALYRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1176461394 603 IQQMEAQHDKTEnEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQ 680
Cdd:COG4942 166 RAELEAERAELE-ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
452-737 |
3.10e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 3.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 452 AQVEKVTKEKISAINQLEEIQSQLASremdVTKVCGEMRYQLNKTNMEKDEAEKehreFRAKTNrdlEIKDQEIEKLRIE 531
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDR----LEDILNELERQLKSLERQAEKAER----YKELKA---ELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 532 LDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTR---QEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEA 608
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRlevSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 609 QHDKTENEQYLLLTSQNTfLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRytydKLGKLQRRNEELEEQcvqhgrvH 688
Cdd:TIGR02168 314 LERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEELESLEAELEELEA----ELEELESRLEELEEQ-------L 381
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1176461394 689 ETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 737
Cdd:TIGR02168 382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
354-509 |
1.12e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 48.62 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 354 VRSSLADTQQREASayEQVKQVLQISE-EANFEKTKALIQC----DQLRKELERQAERLEKELAsQQEKRAIEK----DM 424
Cdd:PRK12704 24 VRKKIAEAKIKEAE--EEAKRILEEAKkEAEAIKKEALLEAkeeiHKLRNEFEKELRERRNELQ-KLEKRLLQKeenlDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 425 MKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIqSQLAS---REMDVTKVCGEMRYQ----LNKTN 497
Cdd:PRK12704 101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERI-SGLTAeeaKEILLEKVEEEARHEaavlIKEIE 179
|
170
....*....|...
gi 1176461394 498 ME-KDEAEKEHRE 509
Cdd:PRK12704 180 EEaKEEADKKAKE 192
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
365-697 |
1.15e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 365 EASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERL---EKELASQQEKRAIEKDMMKKEITKEREYMGSKML 441
Cdd:pfam02463 160 EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 442 ILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIK 521
Cdd:pfam02463 240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 522 DQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQ 601
Cdd:pfam02463 320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 602 KIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQC 681
Cdd:pfam02463 400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479
|
330
....*....|....*.
gi 1176461394 682 VQHGRVHETMKQRLRQ 697
Cdd:pfam02463 480 VKLQEQLELLLSRQKL 495
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
512-733 |
1.21e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.91 E-value: 1.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 512 AKTNRDLEIKDQEIEKLRIELDESKQHLEQ--------EQQKAALAREECLRLTELLGE---SEHQLHLTRQEKDSIQQS 580
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQLERlrrerekaERYQALLKEKREYEGYELLKEkeaLERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 581 FSKeAKAQALQAQQREQELTQKIQQMEAQ-HDKTENEQYLL------LTSQNTFLTKLKEECCTLAKKLEQISQKTRSEI 653
Cdd:TIGR02169 253 LEK-LTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVkekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEI 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 654 AQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRL 733
Cdd:TIGR02169 332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
340-629 |
2.05e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 2.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 340 LVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQA---ERLEKELASQQE 416
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAneiSRLEQQKQILRE 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 417 KRAiEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLAsremdvtkvcgemryQLNKT 496
Cdd:TIGR02168 310 RLA-NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE---------------ELESR 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 497 NMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTelLGESEHQLHLTRQEKDS 576
Cdd:TIGR02168 374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEE 451
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 1176461394 577 IQQSFSkEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLT 629
Cdd:TIGR02168 452 LQEELE-RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
395-736 |
3.84e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.37 E-value: 3.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 395 QLRKELERQAER---LEKELAS-QQEKRAIEKDM------------MKKEITKEREYMGSKMLILSQNIAQLEAQVEKVT 458
Cdd:TIGR02169 671 SEPAELQRLRERlegLKRELSSlQSELRRIENRLdelsqelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 459 KEKISAINQLEEIQSQLASREMDVTKvcgemrYQLNKTNMEKDEAEKEHREFRAKTnrdleikdQEIEKLRIELDESKQH 538
Cdd:TIGR02169 751 QEIENVKSELKELEARIEELEEDLHK------LEEALNDLEARLSHSRIPEIQAEL--------SKLEEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 539 LEQE----QQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQ------QSFSKEAKAQALQAQQREQELTQKIQQMEA 608
Cdd:TIGR02169 817 IEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNgkkeelEEELEELEAALRDLESRLGDLKKERDELEA 896
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 609 QHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRsEIAQLSQEKRYTYDkLGKLQRRNEELEEQCVQHGRVH 688
Cdd:TIGR02169 897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIED-PKGEDEEIPEEELS-LEDVQAELQRVEEEIRALEPVN 974
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1176461394 689 etmkqrLRQLDKHSQaTAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQ 736
Cdd:TIGR02169 975 ------MLAIQEYEE-VLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
446-737 |
5.35e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 5.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 446 NIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMryqlnktnmekDEAEKEHREFRaktnRDLEIKDQEI 525
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL-----------SDASRKIGEIE----KEIEQLEQEE 732
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 526 EKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEakaqalqaqqREQELTQKIQQ 605
Cdd:TIGR02169 733 EKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHS----------RIPEIQAELSK 802
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 606 MEAQHdkTENEQYLLLTSQNTfltklkeecctlaKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHG 685
Cdd:TIGR02169 803 LEEEV--SRIEARLREIEQKL-------------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1176461394 686 RVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 737
Cdd:TIGR02169 868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
335-551 |
5.67e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 5.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 335 QTIERLVKERDDLMSAlvsvRSSLADT-QQREA-----SAYEQVKQVLQISEEANFEKTKALIQCDQLRKEL-ERQAERL 407
Cdd:COG4913 225 EAADALVEHFDDLERA----HEALEDArEQIELlepirELAERYAAARERLAELEYLRAALRLWFAQRRLELlEAELEEL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 408 EKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVT---K 484
Cdd:COG4913 301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPasaE 380
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1176461394 485 VCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQ-----HLEQEQQKAALARE 551
Cdd:COG4913 381 EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERrksniPARLLALRDALAEA 452
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
511-737 |
1.64e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 511 RAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQqsfsKEAKAQAL 590
Cdd:COG4942 22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE----KEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 591 QAQQREQELTQKIQQMEAQHdktENEQYLLLTSQNTFLTKLKeecctLAKKLEQISQKTRSEIAQLSQEKRytydklgKL 670
Cdd:COG4942 98 ELEAQKEELAELLRALYRLG---RQPPLALLLSPEDFLDAVR-----RLQYLKYLAPARREQAEELRADLA-------EL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1176461394 671 QRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 737
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
265-614 |
1.74e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.03 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 265 EEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAAntcnrvgGLCLKCAQheavlsQTHTNVHMQTIERLVKER 344
Cdd:PRK02224 411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEA-------GKCPECGQ------PVEGSPHVETIEEDRERV 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 345 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEAnfEKTKALIQ-CDQLRKELERQAERLEkELASQQEKRAIEKD 423
Cdd:PRK02224 478 EELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLE--ERREDLEElIAERRETIEEKRERAE-ELRERAAELEAEAE 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 424 MMKKEITKEREYMGSKMlilsQNIAQLEAQVEKVTkekiSAINQLEEIQSQLASREmdvtkvcgemryqlnktnmEKDEA 503
Cdd:PRK02224 555 EKREAAAEAEEEAEEAR----EEVAELNSKLAELK----ERIESLERIRTLLAAIA-------------------DAEDE 607
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 504 EKEHREFRAKTNrdlEIKDQEIEKLRiELDESKQHLEQEQQKAAL--AREECLRLTELLGESEHQLHLTRQEKDSIQQSF 581
Cdd:PRK02224 608 IERLREKREALA---ELNDERRERLA-EKRERKRELEAEFDEARIeeAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
|
330 340 350
....*....|....*....|....*....|....*
gi 1176461394 582 SKEAKAQALQAQQREQ--ELTQKIQQMEAQHDKTE 614
Cdd:PRK02224 684 GAVENELEELEELRERreALENRVEALEALYDEAE 718
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
361-734 |
2.00e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 44.96 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 361 TQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEkelasqqEKRAIEKDMMKKEITKEREYMGSKM 440
Cdd:TIGR00618 223 VLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIE-------ELRAQEAVLEETQERINRARKAAPL 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 441 LILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVcGEMRYQLNKTNMEKDEAEKEHREfrAKTNRDLEI 520
Cdd:TIGR00618 296 AAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLHSQEIHIRDAHEV--ATSIREISC 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 521 KDQEIEKLRIELDESKQHLEQEQQKAA-----LAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQR 595
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKLQSLCkeldiLQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 596 EQELTQKIQQMEAQHDKTENEQyllLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQ--EKRYTYDKLGKLQRR 673
Cdd:TIGR00618 453 CEKLEKIHLQESAQSLKEREQQ---LQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnPARQDIDNPGPLTRR 529
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1176461394 674 NEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLR 734
Cdd:TIGR00618 530 MQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQ 590
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
323-732 |
2.17e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.83 E-value: 2.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 323 AVLSQTHTNVHMQTIERLVKERddlmsaLVSVRSSLADTQQREASAYEQVKQVlqiSEEANFEKTKALIQCDQLRKELER 402
Cdd:pfam12128 256 AELRLSHLHFGYKSDETLIASR------QEERQETSAELNQLLRTLDDQWKEK---RDELNGELSAADAAVAKDRSELEA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 403 QAERLEKELASQQEKRAIEKDMMK------KEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAIN-----QLEEI 471
Cdd:pfam12128 327 LEDQHGAFLDADIETAAADQEQLPswqselENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKdklakIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 472 QSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHRE-------------FRAKTNRDLEIKDQEIEKLRIEL------ 532
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSrlgelklrlnqatATPELLLQLENFDERIERAREEQeaanae 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 533 ---------------DESKQHLEQEQQKAALAREECLRLTELLGESEHQL-HLTRQEKDSIQQSFSKEAKAQALQAQQRE 596
Cdd:pfam12128 487 verlqselrqarkrrDQASEALRQASRRLEERQSALDELELQLFPQAGTLlHFLRKEAPDWEQSIGKVISPELLHRTDLD 566
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 597 QELTQKIQQMEAQH-------DKTENEQYLLLTSQntfltkLKEEcctlAKKLEQISQKTRSEIAQLSQEKRYTYDKLGK 669
Cdd:pfam12128 567 PEVWDGSVGGELNLygvkldlKRIDVPEWAASEEE------LRER----LDKAEEALQSAREKQAAAEEQLVQANGELEK 636
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1176461394 670 LQRRnEELEEQCVQHGR--------VHETMKQRL-RQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDR 732
Cdd:pfam12128 637 ASRE-ETFARTALKNARldlrrlfdEKQSEKDKKnKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
335-552 |
2.20e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 335 QTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQ 414
Cdd:COG4942 34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 415 QEKRAIEKDMMK------KEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLAsremdvtkvcge 488
Cdd:COG4942 114 YRLGRQPPLALLlspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA------------ 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1176461394 489 mryQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREE 552
Cdd:COG4942 182 ---ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
356-737 |
4.88e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.35 E-value: 4.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 356 SSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAiEKDMMKKEITKEREY 435
Cdd:pfam07888 34 NRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHE-ELEEKYKELSASSEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 436 MGSKMLILSQNIAQLEAQvekvtkekisaINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKtn 515
Cdd:pfam07888 113 LSEEKDALLAQRAAHEAR-----------IRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAK-- 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 516 rdLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGES---EHQLHLTRQEKDSIQQSFSKEAKAQALQA 592
Cdd:pfam07888 180 --LQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAhrkEAENEALLEELRSLQERLNASERKVEGLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 593 QQREQELTQKIQ-QMEAQHDKTENEQYLLLTSQNTFltKLKEECCTLAKK---LEQISQKTRSEIAQLSQEKRYTYDKLG 668
Cdd:pfam07888 258 EELSSMAAQRDRtQAELHQARLQAAQLTLQLADASL--ALREGRARWAQEretLQQSAEADKDRIEKLSAELQRLEERLQ 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1176461394 669 KLQRRNEELEeqcVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQL 737
Cdd:pfam07888 336 EERMEREKLE---VELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRL 401
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
499-737 |
7.06e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.04 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 499 EKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQ 578
Cdd:pfam02463 171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQ 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 579 QSFSKEAKAQALQAQQREQELTQKIQQMEAQHDK------------TENEQYLLLTSQNTFLTKLKEECCTLAKKLEQIS 646
Cdd:pfam02463 251 EEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQeeelkllakeeeELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 647 QKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSL 726
Cdd:pfam02463 331 KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410
|
250
....*....|.
gi 1176461394 727 SEEVDRLRTQL 737
Cdd:pfam02463 411 LELARQLEDLL 421
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
511-730 |
8.35e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 8.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 511 RAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQK---------AALAREECLRLTELLGESEHQLHLTRQEKDSIQQSF 581
Cdd:COG3206 170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQKnglvdlseeAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 582 SKEAKAQALQAQQRE-QELTQKIQQMEAQhdktENEQYLLLTSQNTFLTKLKEEcctLAKKLEQISQKTRSEIAQLSQEK 660
Cdd:COG3206 250 GSGPDALPELLQSPViQQLRAQLAELEAE----LAELSARYTPNHPDVIALRAQ---IAALRAQLQQEAQRILASLEAEL 322
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 661 RYTYDKLGKLQRRNEELEEQCVQHGRVhetmKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEV 730
Cdd:COG3206 323 EALQAREASLQAQLAQLEARLAELPEL----EAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNV 388
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
345-496 |
9.35e-04 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 41.96 E-value: 9.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 345 DDLMSALVSVRSSLADTQQREASAYEQVKQVLQISE-EANFEKTKAliQCDQLRKELERQAERLEKELASQQEKRAIEkd 423
Cdd:COG1566 79 TDLQAALAQAEAQLAAAEAQLARLEAELGAEAEIAAaEAQLAAAQA--QLDLAQRELERYQALYKKGAVSQQELDEAR-- 154
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1176461394 424 mmkkeitkereymgSKMLILSQNIAQLEAQVEKvTKEKISAINQLEEIQSQLASREMDVTkvcgEMRYQLNKT 496
Cdd:COG1566 155 --------------AALDAAQAQLEAAQAQLAQ-AQAGLREEEELAAAQAQVAQAEAALA----QAELNLART 208
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
404-562 |
1.35e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.15 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 404 AERLEKELASQQEKRAIEKDMMKKEITKEREymgskmlilsqNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVT 483
Cdd:COG2433 383 EELIEKELPEEEPEAEREKEHEERELTEEEE-----------EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELS 451
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1176461394 484 KVcgemryqlnktnmeKDEAEKEHREfraktNRDLEIKDQEIEKLRIELDESKQHLEQEQQKaaLAREECLRLTELLGE 562
Cdd:COG2433 452 EA--------------RSEERREIRK-----DREISRLDREIERLERELEEERERIEELKRK--LERLKELWKLEHSGE 509
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
250-737 |
1.61e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 250 LMTSLQLSEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGglclkcAQHEAVLSQTH 329
Cdd:COG1196 258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE------LEEELAELEEE 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 330 TNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEK 409
Cdd:COG1196 332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 410 ELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEM 489
Cdd:COG1196 412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 490 RYQLNKtNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLR-----------IELDESKQHLEQEQQKAALAREECL---- 554
Cdd:COG1196 492 RLLLLL-EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLkaak 570
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 555 --RLTELLGESEHQLHLTRQEKDSIQQSF----------SKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLT 622
Cdd:COG1196 571 agRATFLPLDKIRARAALAAALARGAIGAavdlvasdlrEADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 623 SQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHS 702
Cdd:COG1196 651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 1176461394 703 QATAQQLVQLLSKQNQLLLE-----------RQSLSEEVDRLRTQL 737
Cdd:COG1196 731 EAEREELLEELLEEEELLEEealeelpeppdLEELERELERLEREI 776
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
372-583 |
3.29e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 40.82 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 372 VKQVLQISEEANFEKTKAliqcdQLRKELERQAERLEKELASQQEkraIEKdmMKKEITKEREYMGSKMLILSQNIAQLE 451
Cdd:PRK03918 151 VRQILGLDDYENAYKNLG-----EVIKEIKRRIERLEKFIKRTEN---IEE--LIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 452 AQVEKVTKEKisaiNQLEEIQSQLASREMDVTKVCGEMR---YQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQ----- 523
Cdd:PRK03918 221 EELEKLEKEV----KELEELKEEIEELEKELESLEGSKRkleEKIRELEERIEELKKEIEELEEKVKELKELKEKaeeyi 296
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 524 EIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSK 583
Cdd:PRK03918 297 KLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
370-617 |
7.09e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 40.12 E-value: 7.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 370 EQVKQVLQISEEANFEKTKAliqcDQLRK--ELERQAERLEK--------ELASQQEKRAIEKDMMKKEITKEREYMGSK 439
Cdd:PTZ00121 1480 EEAKKADEAKKKAEEAKKKA----DEAKKaaEAKKKADEAKKaeeakkadEAKKAEEAKKADEAKKAEEKKKADELKKAE 1555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 440 MLILSQNIAQLEaQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRY----QLNKTNMEKDEAE--------KEH 507
Cdd:PTZ00121 1556 ELKKAEEKKKAE-EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKmkaeEAKKAEEAKIKAEelkkaeeeKKK 1634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 508 REFRAKTNRDLEIKDQEI----EKLRIELDESKQHLEQEQQKAALAREEclrlTELLGESEHQLHLTRQEKDSIQQSFSK 583
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELkkaeEENKIKAAEEAKKAEEDKKKAEEAKKA----EEDEKKAAEALKKEAEEAKKAEELKKK 1710
|
250 260 270
....*....|....*....|....*....|....
gi 1176461394 584 EAKAQALQAQQREQELTQKIQQMEAQHDKTENEQ 617
Cdd:PTZ00121 1711 EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK 1744
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
536-740 |
8.22e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 39.65 E-value: 8.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 536 KQHLEQEQQKAALAREECLRLTELLGESEHQL-HLTRQ------------EKDSIQQSFSKEAKAQALQAQQREQELTQK 602
Cdd:TIGR02168 171 KERRKETERKLERTRENLDRLEDILNELERQLkSLERQaekaerykelkaELRELELALLVLRLEELREELEELQEELKE 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1176461394 603 IQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQktrsEIAQLSQEKRYTYDKLGKLQRRNEELEEQcv 682
Cdd:TIGR02168 251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN----EISRLEQQKQILRERLANLERQLEELEAQ-- 324
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1176461394 683 qhgrvhetmkqrLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLPSM 740
Cdd:TIGR02168 325 ------------LEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
|
|
| |
