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Conserved domains on  [gi|1208915094|ref|NP_001339607|]
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calcium-responsive transcription factor isoform 8 [Homo sapiens]

Protein Classification

ALS2CR8 domain-containing protein( domain architecture ID 10633845)

ALS2CR8 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ALS2CR8 super family cl21146
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in ...
 1-139 8.63e-52

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein.


The actual alignment was detected with superfamily member pfam15299:

Pssm-ID: 464625  Cd Length: 227  Bit Score: 172.22  E-value: 8.63e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208915094   1 MEQEKAFnmLKKNLVDAGGVLRWYVQLPTQQAHQYHELETPCLTLSPSPFpvssleeeetavrdENCALPSRLHPQVAHK 80
Cdd:pfam15299 105 DALKTDF--LKNGPSEIGGELRYYVQLPAIDEHEGHPLGGVAAVLAPAPK--------------DCCNSSQRLDPQVKEK 168

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1208915094  81 IQELVSQGIEQVYAVRKQLRKFVERELFKPDEVPERHNLSFFPTVNDIKNHIHEVQKSL 139
Cdd:pfam15299 169 IGELVAAGLDSVYEVKKQLKKFVEKELFKGKKPPPRHNKRFFPTVRDIKNHMHEAQKTL 227
 
Name Accession Description Interval E-value
ALS2CR8 pfam15299
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in ...
 1-139 8.63e-52

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein.


Pssm-ID: 464625  Cd Length: 227  Bit Score: 172.22  E-value: 8.63e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208915094   1 MEQEKAFnmLKKNLVDAGGVLRWYVQLPTQQAHQYHELETPCLTLSPSPFpvssleeeetavrdENCALPSRLHPQVAHK 80
Cdd:pfam15299 105 DALKTDF--LKNGPSEIGGELRYYVQLPAIDEHEGHPLGGVAAVLAPAPK--------------DCCNSSQRLDPQVKEK 168

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1208915094  81 IQELVSQGIEQVYAVRKQLRKFVERELFKPDEVPERHNLSFFPTVNDIKNHIHEVQKSL 139
Cdd:pfam15299 169 IGELVAAGLDSVYEVKKQLKKFVEKELFKGKKPPPRHNKRFFPTVRDIKNHMHEAQKTL 227
 
Name Accession Description Interval E-value
ALS2CR8 pfam15299
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in ...
 1-139 8.63e-52

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8; This domain is found in amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein.


Pssm-ID: 464625  Cd Length: 227  Bit Score: 172.22  E-value: 8.63e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1208915094   1 MEQEKAFnmLKKNLVDAGGVLRWYVQLPTQQAHQYHELETPCLTLSPSPFpvssleeeetavrdENCALPSRLHPQVAHK 80
Cdd:pfam15299 105 DALKTDF--LKNGPSEIGGELRYYVQLPAIDEHEGHPLGGVAAVLAPAPK--------------DCCNSSQRLDPQVKEK 168

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1208915094  81 IQELVSQGIEQVYAVRKQLRKFVERELFKPDEVPERHNLSFFPTVNDIKNHIHEVQKSL 139
Cdd:pfam15299 169 IGELVAAGLDSVYEVKKQLKKFVEKELFKGKKPPPRHNKRFFPTVRDIKNHMHEAQKTL 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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