NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1245897723|ref|NP_001342620|]
View 

tetratricopeptide repeat protein 17 isoform 3 precursor [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
610-724 1.24e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILneaGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG0457    36 ELDPDDAEALYNL---GLAYLRLGRYEEALADYEQALELDPDDAE--ALNNLGLALQALGRYEEALEDYDKALELDPDDA 110

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG0457   111 EALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
226-406 5.30e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.93  E-value: 5.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 226 WVLYNLASFYWRIKNEPyQVVECAMRALHFSSRHnkDIALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNI 304
Cdd:COG0457    43 EALYNLGLAYLRLGRYE-EALADYEQALELDPDD--AEALNNLGLALQALGRYEEALEDYDKALElDPDDAEALYNLGLA 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 305 YAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKL 384
Cdd:COG0457   120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199

                         170       180
                  ....*....|....*....|..
gi 1245897723 385 IQEEQILRNIIHETQMAKEAQL 406
Cdd:COG0457   200 LLALEQALRKKLAILTLAALAE 221
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
610-724 1.24e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILneaGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG0457    36 ELDPDDAEALYNL---GLAYLRLGRYEEALADYEQALELDPDDAE--ALNNLGLALQALGRYEEALEDYDKALELDPDDA 110

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG0457   111 EALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
226-406 5.30e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.93  E-value: 5.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 226 WVLYNLASFYWRIKNEPyQVVECAMRALHFSSRHnkDIALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNI 304
Cdd:COG0457    43 EALYNLGLAYLRLGRYE-EALADYEQALELDPDD--AEALNNLGLALQALGRYEEALEDYDKALElDPDDAEALYNLGLA 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 305 YAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKL 384
Cdd:COG0457   120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199

                         170       180
                  ....*....|....*....|..
gi 1245897723 385 IQEEQILRNIIHETQMAKEAQL 406
Cdd:COG0457   200 LLALEQALRKKLAILTLAALAE 221
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 573-718 2.84e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 573 RMDLKAKIPDD--------------HARKIL-LSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGlYWRAVGNSTF 637
Cdd:TIGR02917 507 RIDIQEGNPDDaiqrfekvltidpkNLRAILaLAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQ-YYLGKGQLKK 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPVQYQDIPLvnLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:TIGR02917 586 ALAILNEAADAAPDSPEAWLM--LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663


                  .
gi 1245897723 718 L 718
Cdd:TIGR02917 664 L 664
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
 329-410 4.16e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 43.33  E-value: 4.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 329 EQAIKRKHAVL--CQQKLEQKLEAQHRSLQRTLNELKE-YQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQ 405
Cdd:cd16269   207 AEAAEQERKLLeeQQRELEQKLEDQERSYEEHLRQLKEkMEEERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEE 286


                  ....*
gi 1245897723 406 LGNHQ 410
Cdd:cd16269   287 IRSLK 291
TPR_12 pfam13424
Tetratricopeptide repeat;
658-721 1.21e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 1.21e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1245897723 658 LVNLANLLIHYGLHLDATKLLLQAVAVNSSEP--------LTFLSLGNAYLALKNVSGALEAFRQALKLSTK 721
Cdd:pfam13424   6 LNNLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 689-718 3.70e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.89  E-value: 3.70e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 1245897723  689 PLTFLSLGNAYLALKNVSGALEAFRQALKL 718
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
TPR_1 pfam00515
Tetratricopeptide repeat;
297-328 7.43e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.43e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1245897723 297 SYYTLGNIYAMLGEYNHSVLCYDHALQAKPGF 328
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
610-724 1.24e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 1.24e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILneaGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG0457    36 ELDPDDAEALYNL---GLAYLRLGRYEEALADYEQALELDPDDAE--ALNNLGLALQALGRYEEALEDYDKALELDPDDA 110

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG0457   111 EALYNLGLALLELGRYDEAIEAYERALELDPDDAD 145
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
610-724 2.63e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.56  E-value: 2.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILneaGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG0457     2 ELDPDDAEAYNNL---GLAYRRLGRYEEAIEDYEKALELDPDDAE--ALYNLGLAYLRLGRYEEALADYEQALELDPDDA 76

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG0457    77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAE 111
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 610-729 3.37e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.86  E-value: 3.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILNEAglyWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG3914   106 ALNPDNAEALFNLGNL---LLALGRLEEALAALRRALALNPDFAE--AYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSL 729
Cdd:COG3914   181 EALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 621-724 4.48e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 4.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 621 ILNEAGLYWRAVGNSTFAIACLQRALNLAPvQYQDIpLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYL 700
Cdd:COG3914    80 LLELAALLLQALGRYEEALALYRRALALNP-DNAEA-LFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALR 157

                          90       100
                  ....*....|....*....|....
gi 1245897723 701 ALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG3914   158 RLGRLEEAIAALRRALELDPDNAE 181
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 615-719 4.51e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 4.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 615 NAPVWLILneaGLYWRAVGNSTFAIACLQRALNLAPvQYQDIpLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLS 694
Cdd:COG4235    16 DAEGWLLL---GRAYLRLGRYDEALAAYEKALRLDP-DNADA-LLDLAEALLAAGDTEEAEELLERALALDPDNPEALYL 90

                          90       100
                  ....*....|....*....|....*
gi 1245897723 695 LGNAYLALKNVSGALEAFRQALKLS 719
Cdd:COG4235    91 LGLAAFQQGDYAEAIAAWQKLLALL 115
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 622-724 3.08e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.35  E-value: 3.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 622 LNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLA 701
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPE--AFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100
                  ....*....|....*....|...
gi 1245897723 702 LKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPE 107
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 633-719 1.91e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.58  E-value: 1.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 633 GNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAF 712
Cdd:COG5010    68 GDFEESLALLEQALQLDPNNPE--LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAAL 145


                  ....*..
gi 1245897723 713 RQALKLS 719
Cdd:COG5010   146 QRALGTS 152
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
619-733 8.45e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.77  E-value: 8.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 619 WLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNA 698
Cdd:COG4785    73 AQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAE--AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 699 YLALKNVSGALEAFRQALKLSTKCPECESSLKLIR 733
Cdd:COG4785   151 LYYLGRYELAIADLEKALELDPNDPERALWLYLAE 185
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
226-406 5.30e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.93  E-value: 5.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 226 WVLYNLASFYWRIKNEPyQVVECAMRALHFSSRHnkDIALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNI 304
Cdd:COG0457    43 EALYNLGLAYLRLGRYE-EALADYEQALELDPDD--AEALNNLGLALQALGRYEEALEDYDKALElDPDDAEALYNLGLA 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 305 YAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKL 384
Cdd:COG0457   120 LLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199

                         170       180
                  ....*....|....*....|..
gi 1245897723 385 IQEEQILRNIIHETQMAKEAQL 406
Cdd:COG0457   200 LLALEQALRKKLAILTLAALAE 221
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
621-717 8.01e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 8.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 621 ILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYL 700
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAE--ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                          90
                  ....*....|....*..
gi 1245897723 701 ALKNVSGALEAFRQALK 717
Cdd:COG0457   156 KLGRYEEALELLEKLEA 172
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
628-719 1.16e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.47  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 628 YWRAVGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLlQAVAVNSSEPLTFLSLGNAYLALKNVSG 707
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNAD--ALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAEALLNLAELLLELGDYDE 77

                          90
                  ....*....|..
gi 1245897723 708 ALEAFRQALKLS 719
Cdd:COG3063    78 ALAYLERALELD 89
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 638-719 4.34e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 4.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:COG4783    57 AIVLLHEALELDPDEPE--ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134


                  ..
gi 1245897723 718 LS 719
Cdd:COG4783   135 LD 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 638-725 5.11e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 5.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:COG2956    61 AIRIHQKLLERDPDRAE--ALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK 138


                  ....*...
gi 1245897723 718 LSTKCPEC 725
Cdd:COG2956   139 LGPENAHA 146
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 638-718 1.59e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.80  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:COG2956   129 AIEVLERLLKLGPENAH--AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE 206


                  .
gi 1245897723 718 L 718
Cdd:COG2956   207 Q 207
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 573-718 2.84e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 573 RMDLKAKIPDD--------------HARKIL-LSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGlYWRAVGNSTF 637
Cdd:TIGR02917 507 RIDIQEGNPDDaiqrfekvltidpkNLRAILaLAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQ-YYLGKGQLKK 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPVQYQDIPLvnLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:TIGR02917 586 ALAILNEAADAAPDSPEAWLM--LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALE 663


                  .
gi 1245897723 718 L 718
Cdd:TIGR02917 664 L 664
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 610-724 4.57e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 4.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 610 AINKPNAPVWLILneAGLYWRAvGNSTFAIACLQRALNLAPVQYQdiPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEP 689
Cdd:COG2956    70 ERDPDRAEALLEL--AQDYLKA-GLLDRAEELLEKLLELDPDDAE--ALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1245897723 690 LTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPE 724
Cdd:COG2956   145 HAYCELAELYLEQGDYDEAIEALEKALKLDPDCAR 179
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 622-718 7.96e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.52  E-value: 7.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 622 LNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDiplvnlANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLA 701
Cdd:COG3914    51 LAEAAAAALLALAAGEAAAAAAALLLLAALLELA------ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLA 124

                          90
                  ....*....|....*..
gi 1245897723 702 LKNVSGALEAFRQALKL 718
Cdd:COG3914   125 LGRLEEALAALRRALAL 141
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 621-718 2.05e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 2.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 621 ILNEAGLYWRAVGNSTFAIACLQRALNLAPvqyQDIP-LVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAY 699
Cdd:COG2956   146 AYCELAELYLEQGDYDEAIEALEKALKLDP---DCARaLLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELY 222

                          90
                  ....*....|....*....
gi 1245897723 700 LALKNVSGALEAFRQALKL 718
Cdd:COG2956   223 EKLGDPEEALELLRKALEL 241
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 638-729 3.41e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.56  E-value: 3.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 638 AIACLQRALNLAPvQYQDIpLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALK 717
Cdd:COG2956    27 AIDLLEEALELDP-ETVEA-HLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLE 104

                          90
                  ....*....|..
gi 1245897723 718 LSTKCPECESSL 729
Cdd:COG2956   105 LDPDDAEALRLL 116
GBP_C cd16269
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ...
 329-410 4.16e-04

Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.


Pssm-ID: 293879 [Multi-domain]  Cd Length: 291  Bit Score: 43.33  E-value: 4.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 329 EQAIKRKHAVL--CQQKLEQKLEAQHRSLQRTLNELKE-YQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQ 405
Cdd:cd16269   207 AEAAEQERKLLeeQQRELEQKLEDQERSYEEHLRQLKEkMEEERENLLKEQERALESKLKEQEALLEEGFKEQAELLQEE 286


                  ....*
gi 1245897723 406 LGNHQ 410
Cdd:cd16269   287 IRSLK 291
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 615-736 8.02e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 8.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 615 NAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHY--GLHLDATKLLLQAVAVNSSEPLTF 692
Cdd:COG5010    12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNklGDFEESLALLEQALQLDPNNPELY 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1245897723 693 LSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQ 736
Cdd:COG5010    92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSL 135
ClassIIa_HDAC5_Gln-rich-N cd10164
Glutamine-rich N-terminal helical domain of HDAC5, a Class IIa histone deacetylase; This ...
 338-424 9.17e-04

Glutamine-rich N-terminal helical domain of HDAC5, a Class IIa histone deacetylase; This family consists of the glutamine-rich domain of histone deacetylase 5 (HDAC5). It belongs to a superfamily that consists of the glutamine-rich N-terminal helical extension to certain Class IIa histone deacetylases (HDACs), including HDAC4, HDAC5 and HDCA9; it is missing from HDAC7. This domain confers responsiveness to calcium signals and mediates interactions with transcription factors and cofactors, and it is able to repress transcription independently of the HDAC C-terminal, zinc-dependent catalytic domain. It has many intra- and inter-helical interactions which are possibly involved in reversible assembly and disassembly of proteins. HDACs regulate diverse cellular processes through enzymatic deacetylation of histone as well as non-histone proteins, in particular deacetylating N(6)-acetyl-lysine residues.


Pssm-ID: 197400 [Multi-domain]  Cd Length: 97  Bit Score: 39.42  E-value: 9.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 338 VLCQQKLEQKLEA--QHRSLQRTLnELKEYQKQHDHYLRQQEI-LEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRL 414
Cdd:cd10164     3 SLREQQLQQELLLlkQQQQLQKQL-LFAEFQKQHEHLTRQHEVqLQKHLKVRAELFSEQQQQEILAAKRQQELEQQRKRE 81

                          90
                  ....*....|
gi 1245897723 415 VNQQHSLHCQ 424
Cdd:cd10164    82 QQRQEELEKQ 91
TPR_12 pfam13424
Tetratricopeptide repeat;
658-721 1.21e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.52  E-value: 1.21e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1245897723 658 LVNLANLLIHYGLHLDATKLLLQAVAVNSSEP--------LTFLSLGNAYLALKNVSGALEAFRQALKLSTK 721
Cdd:pfam13424   6 LNNLAAVLRRLGRYDEALELLEKALEIARRLLgpdhpltaTTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 673-719 2.21e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 2.21e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1245897723 673 DATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLS 719
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD 47
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 172-385 2.25e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.52  E-value: 2.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 172 AFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHeGLQKNASS-WVLYNLASFYwRIKNEPYQVVECAM 250
Cdd:COG3914    59 LLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRR-ALALNPDNaEALFNLGNLL-LALGRLEEALAALR 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 251 RALHFSSRHNKdiALVNLANVLHRAH-FSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFE 329
Cdd:COG3914   137 RALALNPDFAE--AYLNLGEALRRLGrLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNA 214

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1245897723 330 QAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQ---QEILEKHKLI 385
Cdd:COG3914   215 DAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDddpAELLALARAW 273
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
291-356 3.45e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 3.45e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1245897723 291 DSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQ-KLEQKLEAQHRSLQ 356
Cdd:COG0457     4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLgRYEEALADYEQALE 70
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 689-718 3.70e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.89  E-value: 3.70e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 1245897723  689 PLTFLSLGNAYLALKNVSGALEAFRQALKL 718
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALEL 30
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 673-719 6.17e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.16  E-value: 6.17e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1245897723 673 DATKLLLQAVAVNSSEPLTF---LSLGNAYLALKNVSGALEAFRQALKLS 719
Cdd:pfam13432  15 DAAAALEAALARFPESPDAAaalLLLGLAALRQGRLAEAAAAYRAALRAA 64
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
291-378 6.57e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 6.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 291 DSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQK--------LEQKLEAQ------HRSLQ 356
Cdd:COG0457    38 DPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGryeealedYDKALELDpddaeaLYNLG 117

                          90       100
                  ....*....|....*....|..
gi 1245897723 357 RTLNELKEYQKQHDHYLRQQEI 378
Cdd:COG0457   118 LALLELGRYDEAIEAYERALEL 139
TPR_1 pfam00515
Tetratricopeptide repeat;
297-328 7.43e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.43e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1245897723 297 SYYTLGNIYAMLGEYNHSVLCYDHALQAKPGF 328
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
689-718 7.96e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 7.96e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1245897723 689 PLTFLSLGNAYLALKNVSGALEAFRQALKL 718
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 695-718 8.03e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.81  E-value: 8.03e-03
                          10        20
                  ....*....|....*....|....
gi 1245897723 695 LGNAYLALKNVSGALEAFRQALKL 718
Cdd:pfam07719   7 LGLAYYKLGDYEEALEAYEKALEL 30
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
226-392 8.67e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.83  E-value: 8.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 226 WVLYNLASFYWRIkNEPYQVVECAMRALHFSSRHNKdiALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNI 304
Cdd:COG0457    77 EALNNLGLALQAL-GRYEEALEDYDKALELDPDDAE--ALYNLGLALLELGRYDEAIEAYERALElDPDDADALYNLGIA 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1245897723 305 YAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKL 384
Cdd:COG0457   154 LEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLAL 233


                  ....*...
gi 1245897723 385 IQEEQILR 392
Cdd:COG0457   234 RLAALALY 241
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH