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Conserved domains on  [gi|1248495068|ref|NP_001343300|]
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transcription cofactor vestigial-like protein 4 isoform 2 [Mus musculus]

Protein Classification

VGLL4 and TDU domain-containing protein( domain architecture ID 10633645)

VGLL4 and TDU domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 2-215 2.50e-90

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


:

Pssm-ID: 464585  Cd Length: 216  Bit Score: 267.11  E-value: 2.50e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068   2 ETPLDVLSRAASLVHADDEKREASLRGEPRMQTLpvaSALSSHRTGPPPISPSKRKFSMEPGDKDLDcENDHVSKMSRIF 81
Cdd:pfam15245   1 LLNFQYLDKMNNNIGVLIYEGEAALRGEPRMRSL---SAVSNHRTGPPPVSPVKRKLSGEQGDDDFD-DNEHVAKMSRLF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068  82 SPHLNKTvNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSL-MEQPLALTKNSSD---------TGRSAVERQQN 151
Cdd:pfam15245  77 ATQLGKS-NGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYaMDQPLALTKNSMKdsartaeisPTSGAVERQQN 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1248495068 152 RPSVITCASAGARNCNLSHCPIahSGCSAPgSASYRRPPSATATCDPVVEEHFRRSLGKNYKEP 215
Cdd:pfam15245 156 RPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLGKNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 225-240 8.49e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


:

Pssm-ID: 197839  Cd Length: 16  Bit Score: 35.92  E-value: 8.49e-04
                           10
                   ....*....|....*.
gi 1248495068  225 TGSVDDHFAKALGDTW 240
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 2-215 2.50e-90

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 267.11  E-value: 2.50e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068   2 ETPLDVLSRAASLVHADDEKREASLRGEPRMQTLpvaSALSSHRTGPPPISPSKRKFSMEPGDKDLDcENDHVSKMSRIF 81
Cdd:pfam15245   1 LLNFQYLDKMNNNIGVLIYEGEAALRGEPRMRSL---SAVSNHRTGPPPVSPVKRKLSGEQGDDDFD-DNEHVAKMSRLF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068  82 SPHLNKTvNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSL-MEQPLALTKNSSD---------TGRSAVERQQN 151
Cdd:pfam15245  77 ATQLGKS-NGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYaMDQPLALTKNSMKdsartaeisPTSGAVERQQN 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1248495068 152 RPSVITCASAGARNCNLSHCPIahSGCSAPgSASYRRPPSATATCDPVVEEHFRRSLGKNYKEP 215
Cdd:pfam15245 156 RPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLGKNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 197-212 6.39e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 6.39e-04
                           10
                   ....*....|....*.
gi 1248495068  197 DPVVEEHFRRSLGKNY 212
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 225-240 8.49e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 35.92  E-value: 8.49e-04
                           10
                   ....*....|....*.
gi 1248495068  225 TGSVDDHFAKALGDTW 240
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Name Accession Description Interval E-value
VGLL4 pfam15245
Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional ...
 2-215 2.50e-90

Transcription cofactor vestigial-like protein 4; These proteins act as transcriptional enhancer factor (TEF-1) cofactors.


Pssm-ID: 464585  Cd Length: 216  Bit Score: 267.11  E-value: 2.50e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068   2 ETPLDVLSRAASLVHADDEKREASLRGEPRMQTLpvaSALSSHRTGPPPISPSKRKFSMEPGDKDLDcENDHVSKMSRIF 81
Cdd:pfam15245   1 LLNFQYLDKMNNNIGVLIYEGEAALRGEPRMRSL---SAVSNHRTGPPPVSPVKRKLSGEQGDDDFD-DNEHVAKMSRLF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248495068  82 SPHLNKTvNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSL-MEQPLALTKNSSD---------TGRSAVERQQN 151
Cdd:pfam15245  77 ATQLGKS-NGDYRQEHFSRSRSPIERATAPSTSLHPNHLYASPPSYaMDQPLALTKNSMKdsartaeisPTSGAVERQQN 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1248495068 152 RPSVITCASAGARNCNLSHCPIahSGCSAPgSASYRRPPSATATCDPVVEEHFRRSLGKNYKEP 215
Cdd:pfam15245 156 RPSVITCAPASNRNCNLSHCPV--NGCPSL-PPDYRRSSSTNTACDPVIEEHFRRSLGKNYKEP 216
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 197-212 6.39e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 36.30  E-value: 6.39e-04
                           10
                   ....*....|....*.
gi 1248495068  197 DPVVEEHFRRSLGKNY 212
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
TDU smart00711
Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.
 225-240 8.49e-04

Short repeats in human TONDU, fly vestigial and other proteins; Unknown function.


Pssm-ID: 197839  Cd Length: 16  Bit Score: 35.92  E-value: 8.49e-04
                           10
                   ....*....|....*.
gi 1248495068  225 TGSVDDHFAKALGDTW 240
Cdd:smart00711   1 TSVVDEHFRRALGGNW 16
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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