NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1254006583|ref|NP_001343611|]
View 

Serpentine Receptor, class Z [Caenorhabditis elegans]

Protein Classification

class Z serpentine receptor( domain architecture ID 5111)

class Z serpentine receptor (Srz) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srz super family cl10995
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 27-190 2.24e-35

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


The actual alignment was detected with superfamily member pfam10325:

Pssm-ID: 431214  Cd Length: 264  Bit Score: 125.78  E-value: 2.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583  27 IIILIYFLLFPFYVYVNKANRKRDQAVLIYPFTKHFFKMTVVMSILYVIFIAGMLSGVLFLVRKSPYIAVSGLAIFFAIQ 106
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583 107 ALSLVTHVFNLLLSLLGIAKFILYFFPSQEKRVSSIQKSVYRRIWLLYVACSFEDAILYVWVLRENEMNIIKIGLLVFTN 186
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKSLGWETIKYVYL 165


                  ....
gi 1254006583 187 DMYI 190
Cdd:pfam10325 166 IIFI 169
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 27-190 2.24e-35

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 125.78  E-value: 2.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583  27 IIILIYFLLFPFYVYVNKANRKRDQAVLIYPFTKHFFKMTVVMSILYVIFIAGMLSGVLFLVRKSPYIAVSGLAIFFAIQ 106
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583 107 ALSLVTHVFNLLLSLLGIAKFILYFFPSQEKRVSSIQKSVYRRIWLLYVACSFEDAILYVWVLRENEMNIIKIGLLVFTN 186
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKSLGWETIKYVYL 165


                  ....
gi 1254006583 187 DMYI 190
Cdd:pfam10325 166 IIFI 169
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 27-190 2.24e-35

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 125.78  E-value: 2.24e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583  27 IIILIYFLLFPFYVYVNKANRKRDQAVLIYPFTKHFFKMTVVMSILYVIFIAGMLSGVLFLVRKSPYIAVSGLAIFFAIQ 106
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254006583 107 ALSLVTHVFNLLLSLLGIAKFILYFFPSQEKRVSSIQKSVYRRIWLLYVACSFEDAILYVWVLRENEMNIIKIGLLVFTN 186
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKSLGWETIKYVYL 165


                  ....
gi 1254006583 187 DMYI 190
Cdd:pfam10325 166 IIFI 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH