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Conserved domains on  [gi|1327571390|ref|NP_001346694|]
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Serpentine Receptor, class H [Caenorhabditis elegans]

Protein Classification

serpentine receptor domain-containing protein( domain architecture ID 27798)

serpentine receptor domain-containing protein which belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srh super family cl11665
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 25-316 3.47e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10318:

Pssm-ID: 416353  Cd Length: 302  Bit Score: 77.58  E-value: 3.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390  25 HIFGLFTF-LYPLTYYVVLFKTPKNFGSLKWFL-VFHIFSITCQWLCSFLLVNfYTFVPSKITRIDGLLIDF-IDINTLF 101
Cdd:pfam10318  11 HIITVISIpIHIFGFYCILFKTPKKMKSVKWSLlNLHFWSALLDLSLSFLTIP-YIFLPALAGYPLGLLSYLgVPTPIQF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 102 TSMYVVYSLASSSCLLLFCNRILSIL-NMYRKSKTCIRRFFELILYIFVFLFPNIMFygFQIPDQSSIKEMTKQISP-YY 179
Cdd:pfam10318  90 YIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLFLIPIY--LNIPDQEAAKLKVLKKLPcLP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 180 PDCIDNPNIIVFISPDTekqkksLIFYLIYLLSLAIASILSAQFA---YFLLSKRMTNQSEKTRKMHQKFNRRTLFQVLI 256
Cdd:pfam10318 168 PEFFDNPPVFVLAIDST------YFLICIVLLILILIIQILFFVFltiYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSI 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 257 DTSFTSIPFTISNMVTLFRWRVPELTYFVDFTSKSGSTACIFVLFLYYEPYQKWLLEVFR 316
Cdd:pfam10318 242 PLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 25-316 3.47e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 77.58  E-value: 3.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390  25 HIFGLFTF-LYPLTYYVVLFKTPKNFGSLKWFL-VFHIFSITCQWLCSFLLVNfYTFVPSKITRIDGLLIDF-IDINTLF 101
Cdd:pfam10318  11 HIITVISIpIHIFGFYCILFKTPKKMKSVKWSLlNLHFWSALLDLSLSFLTIP-YIFLPALAGYPLGLLSYLgVPTPIQF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 102 TSMYVVYSLASSSCLLLFCNRILSIL-NMYRKSKTCIRRFFELILYIFVFLFPNIMFygFQIPDQSSIKEMTKQISP-YY 179
Cdd:pfam10318  90 YIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLFLIPIY--LNIPDQEAAKLKVLKKLPcLP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 180 PDCIDNPNIIVFISPDTekqkksLIFYLIYLLSLAIASILSAQFA---YFLLSKRMTNQSEKTRKMHQKFNRRTLFQVLI 256
Cdd:pfam10318 168 PEFFDNPPVFVLAIDST------YFLICIVLLILILIIQILFFVFltiYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSI 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 257 DTSFTSIPFTISNMVTLFRWRVPELTYFVDFTSKSGSTACIFVLFLYYEPYQKWLLEVFR 316
Cdd:pfam10318 242 PLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 25-316 3.47e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 77.58  E-value: 3.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390  25 HIFGLFTF-LYPLTYYVVLFKTPKNFGSLKWFL-VFHIFSITCQWLCSFLLVNfYTFVPSKITRIDGLLIDF-IDINTLF 101
Cdd:pfam10318  11 HIITVISIpIHIFGFYCILFKTPKKMKSVKWSLlNLHFWSALLDLSLSFLTIP-YIFLPALAGYPLGLLSYLgVPTPIQF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 102 TSMYVVYSLASSSCLLLFCNRILSIL-NMYRKSKTCIRRFFELILYIFVFLFPNIMFygFQIPDQSSIKEMTKQISP-YY 179
Cdd:pfam10318  90 YIGVTSLALVGVSIILLFENRYSILFtNKKRITWKKTRVLYLIFNYIIALLFLIPIY--LNIPDQEAAKLKVLKKLPcLP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 180 PDCIDNPNIIVFISPDTekqkksLIFYLIYLLSLAIASILSAQFA---YFLLSKRMTNQSEKTRKMHQKFNRRTLFQVLI 256
Cdd:pfam10318 168 PEFFDNPPVFVLAIDST------YFLICIVLLILILIIQILFFVFltiYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSI 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1327571390 257 DTSFTSIPFTISNMVTLFRWRVPELTYFVDFTSKSGSTACIFVLFLYYEPYQKWLLEVFR 316
Cdd:pfam10318 242 PLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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