NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1418589286|ref|NP_001351700|]
View 

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform 2 [Mus musculus]

Protein Classification

PIG-L family deacetylase( domain architecture ID 2293)

PIG-L (phosphatidylinositol glycan class L) family deacetylase catalyzes the removal of an acetyl group from a specific acetylated substrate

CATH:  3.40.50.10320
EC:  3.5.1.-
Gene Ontology:  GO:0010125|GO:0046872
PubMed:  24970229
SCOP:  4001164

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PIG-L super family cl00929
GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an ...
 44-79 2.71e-10

GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.


The actual alignment was detected with superfamily member pfam02585:

Pssm-ID: 445182  Cd Length: 128  Bit Score: 52.30  E-value: 2.71e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1418589286  44 LVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSG 79
Cdd:pfam02585   1 LVVSAHPDDEELGAGGTIARLAAAGVEVHVVCLTDG 36
 
Name Accession Description Interval E-value
PIG-L pfam02585
GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an ...
 44-79 2.71e-10

GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.


Pssm-ID: 426852  Cd Length: 128  Bit Score: 52.30  E-value: 2.71e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1418589286  44 LVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSG 79
Cdd:pfam02585   1 LVVSAHPDDEELGAGGTIARLAAAGVEVHVVCLTDG 36
LmbE COG2120
N-acetylglucosaminyl deacetylase, LmbE family [Carbohydrate transport and metabolism];
42-81 3.23e-05

N-acetylglucosaminyl deacetylase, LmbE family [Carbohydrate transport and metabolism];


Pssm-ID: 441723 [Multi-domain]  Cd Length: 201  Bit Score: 39.91  E-value: 3.23e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1418589286  42 RALVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSGRR 81
Cdd:COG2120     1 RVLVVAAHPDDEELGCGGTIARLAAAGHEVTVVTLTDGEA 40
 
Name Accession Description Interval E-value
PIG-L pfam02585
GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an ...
 44-79 2.71e-10

GlcNAc-PI de-N-acetylase; Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase (EC:3.5.1.89) that catalyzes the second step in GPI biosynthesis.


Pssm-ID: 426852  Cd Length: 128  Bit Score: 52.30  E-value: 2.71e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1418589286  44 LVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSG 79
Cdd:pfam02585   1 LVVSAHPDDEELGAGGTIARLAAAGVEVHVVCLTDG 36
LmbE COG2120
N-acetylglucosaminyl deacetylase, LmbE family [Carbohydrate transport and metabolism];
42-81 3.23e-05

N-acetylglucosaminyl deacetylase, LmbE family [Carbohydrate transport and metabolism];


Pssm-ID: 441723 [Multi-domain]  Cd Length: 201  Bit Score: 39.91  E-value: 3.23e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1418589286  42 RALVVIAHPDDEAMFFAPTMLGLARLEQQVSLLCFSSGRR 81
Cdd:COG2120     1 RVLVVAAHPDDEELGCGGTIARLAAAGHEVTVVTLTDGEA 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH