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Conserved domains on  [gi|1483453018|ref|NP_001353200|]
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protein archease isoform 14 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Archease super family cl00606
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 67-92 4.26e-06

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


The actual alignment was detected with superfamily member pfam01951:

Pssm-ID: 469838  Cd Length: 136  Bit Score: 41.75  E-value: 4.26e-06
                          10        20
                  ....*....|....*....|....*..
gi 1483453018  67 EVKAITYSAMQVYNEEN-PEVFVIIDI 92
Cdd:pfam01951 110 EVKAVTYHELRIEKEDGgWEAQVVVDI 136
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 67-92 4.26e-06

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 41.75  E-value: 4.26e-06
                          10        20
                  ....*....|....*....|....*..
gi 1483453018  67 EVKAITYSAMQVYNEEN-PEVFVIIDI 92
Cdd:pfam01951 110 EVKAVTYHELRIEKEDGgWEAQVVVDI 136
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
 67-92 5.02e-03

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 33.61  E-value: 5.02e-03
                          10        20
                  ....*....|....*....|....*..
gi 1483453018  67 EVKAITYSAMQVYNEENP-EVFVIIDI 92
Cdd:COG1371   113 EVKAVTYHELRVEQEDGGwRAQVVVDV 139
 
Name Accession Description Interval E-value
Archease pfam01951
Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 ...
 67-92 4.26e-06

Archease protein family (MTH1598/TM1083); This archease family of proteins, has two SHS2 domains, with one inserted into another. It is predicted to be an enzyme. It is predicted to act as a chaperone in DNA/RNA metabolism.


Pssm-ID: 426527  Cd Length: 136  Bit Score: 41.75  E-value: 4.26e-06
                          10        20
                  ....*....|....*....|....*..
gi 1483453018  67 EVKAITYSAMQVYNEEN-PEVFVIIDI 92
Cdd:pfam01951 110 EVKAVTYHELRIEKEDGgWEAQVVVDI 136
ARCH COG1371
Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and ...
 67-92 5.02e-03

Archease, activates RNA ligation by RtcB (tRNA splicing) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440982  Cd Length: 139  Bit Score: 33.61  E-value: 5.02e-03
                          10        20
                  ....*....|....*....|....*..
gi 1483453018  67 EVKAITYSAMQVYNEENP-EVFVIIDI 92
Cdd:COG1371   113 EVKAVTYHELRVEQEDGGwRAQVVVDV 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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