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Conserved domains on  [gi|1769843734|ref|NP_001362357|]
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SERTA domain-containing protein 4 isoform 1 [Homo sapiens]

Protein Classification

SERTA domain-containing protein( domain architecture ID 10532710)

SERTA domain-containing protein similar to Homo sapiens cell division cycle associated 4 (CDCA4) that may participate in the regulation of cell proliferation through the E2F/RB pathway

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 108-142 3.93e-10

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


:

Pssm-ID: 461806  Cd Length: 36  Bit Score: 54.47  E-value: 3.93e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1769843734 108 ILYMSLEKLKFIDD-PEVYLRRSVLINNLMKRIHGE 142
Cdd:pfam06031   1 VLNLSLDKLQRSRDlVEPSLRRSVLINNTLRRIQDE 36
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 108-142 3.93e-10

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 54.47  E-value: 3.93e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1769843734 108 ILYMSLEKLKFIDD-PEVYLRRSVLINNLMKRIHGE 142
Cdd:pfam06031   1 VLNLSLDKLQRSRDlVEPSLRRSVLINNTLRRIQDE 36
 
Name Accession Description Interval E-value
SERTA pfam06031
SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and ...
 108-142 3.93e-10

SERTA motif; This family consists of a novel motif designated as SERTA (for SEI-1, RBT1, and TARA), corresponding to the largest conserved region among TRIP-Br proteins. The function of this motif is uncertain, but the CDK4-interacting segment of p34SEI-1 (amino acid residues 44-161) includes most of the SERTA motif.


Pssm-ID: 461806  Cd Length: 36  Bit Score: 54.47  E-value: 3.93e-10
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1769843734 108 ILYMSLEKLKFIDD-PEVYLRRSVLINNLMKRIHGE 142
Cdd:pfam06031   1 VLNLSLDKLQRSRDlVEPSLRRSVLINNTLRRIQDE 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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