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Conserved domains on  [gi|1799133554|ref|NP_001364760|]
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DUF281 domain-containing protein [Caenorhabditis elegans]

Protein Classification

TRA-1 regulated domain-containing protein( domain architecture ID 5459)

TRA-1 regulated domain-containing protein, similar to Caenorhabditis elegans R03H10.4 protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRA-1_regulated super family cl03550
TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of ...
 109-214 1.84e-20

TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of the gene R03H10.4 which is located near a sequence that matches the TRA-1 binding consensus. TRA-1 is a transcription factor which controls sexual differentiation in C.elegans. R03H10.4 shows male-enriched reporter gene expression and acts as a direct target of TRA-1 regulation.


The actual alignment was detected with superfamily member pfam02343:

Pssm-ID: 460535  Cd Length: 129  Bit Score: 83.15  E-value: 1.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133554 109 CPALSSPVIWSQ--MMTVEENGCTEFV-CPEDFVPRVVSTFSRSSIETPPGFTDFtsFIIQPPEPYDAG----INTIDYF 181
Cdd:pfam02343   5 CPDLTSLFDDEEenVEYTEGDGCVRNLtCPAGKLTYVLFSFDESEIPRPDDADDA--FRVVPPTTLAEPpgssIDLFSYF 82

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1799133554 182 GIVC-DGSLAVSQYPRGI---MPLGGDVIGDDGSLDG 214
Cdd:pfam02343  83 GIICeNGKWYATKYPLGIsyfTDDGETYVGADGSLDG 119
 
Name Accession Description Interval E-value
TRA-1_regulated pfam02343
TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of ...
 109-214 1.84e-20

TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of the gene R03H10.4 which is located near a sequence that matches the TRA-1 binding consensus. TRA-1 is a transcription factor which controls sexual differentiation in C.elegans. R03H10.4 shows male-enriched reporter gene expression and acts as a direct target of TRA-1 regulation.


Pssm-ID: 460535  Cd Length: 129  Bit Score: 83.15  E-value: 1.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133554 109 CPALSSPVIWSQ--MMTVEENGCTEFV-CPEDFVPRVVSTFSRSSIETPPGFTDFtsFIIQPPEPYDAG----INTIDYF 181
Cdd:pfam02343   5 CPDLTSLFDDEEenVEYTEGDGCVRNLtCPAGKLTYVLFSFDESEIPRPDDADDA--FRVVPPTTLAEPpgssIDLFSYF 82

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1799133554 182 GIVC-DGSLAVSQYPRGI---MPLGGDVIGDDGSLDG 214
Cdd:pfam02343  83 GIICeNGKWYATKYPLGIsyfTDDGETYVGADGSLDG 119
 
Name Accession Description Interval E-value
TRA-1_regulated pfam02343
TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of ...
 109-214 1.84e-20

TRA-1 regulated protein R03H10.4; This family of proteins represents the protein product of the gene R03H10.4 which is located near a sequence that matches the TRA-1 binding consensus. TRA-1 is a transcription factor which controls sexual differentiation in C.elegans. R03H10.4 shows male-enriched reporter gene expression and acts as a direct target of TRA-1 regulation.


Pssm-ID: 460535  Cd Length: 129  Bit Score: 83.15  E-value: 1.84e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133554 109 CPALSSPVIWSQ--MMTVEENGCTEFV-CPEDFVPRVVSTFSRSSIETPPGFTDFtsFIIQPPEPYDAG----INTIDYF 181
Cdd:pfam02343   5 CPDLTSLFDDEEenVEYTEGDGCVRNLtCPAGKLTYVLFSFDESEIPRPDDADDA--FRVVPPTTLAEPpgssIDLFSYF 82

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1799133554 182 GIVC-DGSLAVSQYPRGI---MPLGGDVIGDDGSLDG 214
Cdd:pfam02343  83 GIICeNGKWYATKYPLGIsyfTDDGETYVGADGSLDG 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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