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Conserved domains on  [gi|1831506368|ref|NP_001366938|]
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Dipeptidyl peptidase 3 [Caenorhabditis elegans]

Protein Classification

dipeptidyl peptidase 3( domain architecture ID 10507915)

dipeptidyl peptidase 3 is an M49 family metallopeptidase that catalyzes the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
144-688 0e+00

Peptidase family M49;


:

Pssm-ID: 460976  Cd Length: 550  Bit Score: 883.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 144 WESVEKVIGSLESNELQLGFGDKG-VTCYHSSN-VTKADAEKIDRFFKQRNVESWNSRLFKEVGSDgkttYTIKLAS--- 218
Cdd:pfam03571   2 WEKVKDAIYSLDPRLLLLGFPSEGhVSTYYSGNdITKEEIEAVQKFLEKKGILPENTRLFKTSDGD----FEILVASnee 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 219 -SEEGIVSEAVEFEGDVVQIVRGDYALIMKRTHEWLDKAIPTAANKNQEEMLRKYVEHFKKGDIALHKDGSRYWIKDVGP 297
Cdd:pfam03571  78 sEEYPEELETGEFNGKKVTLTYGDHSPELKKIVENLEKAKKYAANDTQKKMLEKYIESFETGSIEAHKDSQRHWVKDKGP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 298 AVESYIGFIENYRDPAGTRSEFEGFVAAVNKETSKKFQTLVANAENILKRLPWGTDYEKDTFLKPDFTALDVIAFGSSGI 377
Cdd:pfam03571 158 VVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPLLPWPKDFEKDKFLKPDFTSLEVLTFAGSGI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 378 PAGINIPNYDDIRQNEGFKNVSLGNVISAQ-PKQKMNFLDEHDEELMFKYHKDSFEVQVGLHELLGHGSGKLFQKNLDGT 456
Cdd:pfam03571 238 PAGINIPNYDDIRQNEGFKNVSLGNVLSAKaPNEKITFISEEDQELYKKYRDPAFEVQVGLHELLGHGSGKLLQETADGK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 457 FNFDTNKVKDIITGAPIATWYEPGETWSSKFGPLASAYEECRAEAVGYVLCCDADILEIFGYTGD-LAQEVKYVNWLSEI 535
Cdd:pfam03571 318 FNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVALYLSLNKEVLEIFGFTDKeEADDVIYVNWLQMA 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 536 RAGLLALEFYQAEQKKWGQAHCYARYVLTKVVLEAGQ-GFVKIEETKGEDgkPDLHFKLDRNLIDSVGRPAVNTFLAKLQ 614
Cdd:pfam03571 398 RAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKDED--SDLTIRLDRSKILTVGKPAIGDFLLKLQ 475

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1831506368 615 AYKSTGDFEGGKRLFESYGVVGDTELHWRDICIARRKPRRLFVQPNTV-EKNGEISLVTYSSDVSGVIQSFVERY 688
Cdd:pfam03571 476 VYKSTADVEAGTEFYEDYTTVDEEFLKWRDIVLAKKQPRKVFVQANTVlNDGGKVELKEYEETPEGMIQSFVERF 550
 
Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
144-688 0e+00

Peptidase family M49;


Pssm-ID: 460976  Cd Length: 550  Bit Score: 883.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 144 WESVEKVIGSLESNELQLGFGDKG-VTCYHSSN-VTKADAEKIDRFFKQRNVESWNSRLFKEVGSDgkttYTIKLAS--- 218
Cdd:pfam03571   2 WEKVKDAIYSLDPRLLLLGFPSEGhVSTYYSGNdITKEEIEAVQKFLEKKGILPENTRLFKTSDGD----FEILVASnee 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 219 -SEEGIVSEAVEFEGDVVQIVRGDYALIMKRTHEWLDKAIPTAANKNQEEMLRKYVEHFKKGDIALHKDGSRYWIKDVGP 297
Cdd:pfam03571  78 sEEYPEELETGEFNGKKVTLTYGDHSPELKKIVENLEKAKKYAANDTQKKMLEKYIESFETGSIEAHKDSQRHWVKDKGP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 298 AVESYIGFIENYRDPAGTRSEFEGFVAAVNKETSKKFQTLVANAENILKRLPWGTDYEKDTFLKPDFTALDVIAFGSSGI 377
Cdd:pfam03571 158 VVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPLLPWPKDFEKDKFLKPDFTSLEVLTFAGSGI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 378 PAGINIPNYDDIRQNEGFKNVSLGNVISAQ-PKQKMNFLDEHDEELMFKYHKDSFEVQVGLHELLGHGSGKLFQKNLDGT 456
Cdd:pfam03571 238 PAGINIPNYDDIRQNEGFKNVSLGNVLSAKaPNEKITFISEEDQELYKKYRDPAFEVQVGLHELLGHGSGKLLQETADGK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 457 FNFDTNKVKDIITGAPIATWYEPGETWSSKFGPLASAYEECRAEAVGYVLCCDADILEIFGYTGD-LAQEVKYVNWLSEI 535
Cdd:pfam03571 318 FNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVALYLSLNKEVLEIFGFTDKeEADDVIYVNWLQMA 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 536 RAGLLALEFYQAEQKKWGQAHCYARYVLTKVVLEAGQ-GFVKIEETKGEDgkPDLHFKLDRNLIDSVGRPAVNTFLAKLQ 614
Cdd:pfam03571 398 RAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKDED--SDLTIRLDRSKILTVGKPAIGDFLLKLQ 475

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1831506368 615 AYKSTGDFEGGKRLFESYGVVGDTELHWRDICIARRKPRRLFVQPNTV-EKNGEISLVTYSSDVSGVIQSFVERY 688
Cdd:pfam03571 476 VYKSTADVEAGTEFYEDYTTVDEEFLKWRDIVLAKKQPRKVFVQANTVlNDGGKVELKEYEETPEGMIQSFVERF 550
 
Name Accession Description Interval E-value
Peptidase_M49 pfam03571
Peptidase family M49;
144-688 0e+00

Peptidase family M49;


Pssm-ID: 460976  Cd Length: 550  Bit Score: 883.36  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 144 WESVEKVIGSLESNELQLGFGDKG-VTCYHSSN-VTKADAEKIDRFFKQRNVESWNSRLFKEVGSDgkttYTIKLAS--- 218
Cdd:pfam03571   2 WEKVKDAIYSLDPRLLLLGFPSEGhVSTYYSGNdITKEEIEAVQKFLEKKGILPENTRLFKTSDGD----FEILVASnee 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 219 -SEEGIVSEAVEFEGDVVQIVRGDYALIMKRTHEWLDKAIPTAANKNQEEMLRKYVEHFKKGDIALHKDGSRYWIKDVGP 297
Cdd:pfam03571  78 sEEYPEELETGEFNGKKVTLTYGDHSPELKKIVENLEKAKKYAANDTQKKMLEKYIESFETGSIEAHKDSQRHWVKDKGP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 298 AVESYIGFIENYRDPAGTRSEFEGFVAAVNKETSKKFQTLVANAENILKRLPWGTDYEKDTFLKPDFTALDVIAFGSSGI 377
Cdd:pfam03571 158 VVETNIGFIETYRDPAGVRGEFEGFVAIVNKERSAKFGKLVDNAEKFIPLLPWPKDFEKDKFLKPDFTSLEVLTFAGSGI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 378 PAGINIPNYDDIRQNEGFKNVSLGNVISAQ-PKQKMNFLDEHDEELMFKYHKDSFEVQVGLHELLGHGSGKLFQKNLDGT 456
Cdd:pfam03571 238 PAGINIPNYDDIRQNEGFKNVSLGNVLSAKaPNEKITFISEEDQELYKKYRDPAFEVQVGLHELLGHGSGKLLQETADGK 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 457 FNFDTNKVKDIITGAPIATWYEPGETWSSKFGPLASAYEECRAEAVGYVLCCDADILEIFGYTGD-LAQEVKYVNWLSEI 535
Cdd:pfam03571 318 FNFDKENPPNPLTGKPITSWYKPGETWGSVFGSLASSYEECRAECVALYLSLNKEVLEIFGFTDKeEADDVIYVNWLQMA 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831506368 536 RAGLLALEFYQAEQKKWGQAHCYARYVLTKVVLEAGQ-GFVKIEETKGEDgkPDLHFKLDRNLIDSVGRPAVNTFLAKLQ 614
Cdd:pfam03571 398 RAGLLALEFYDPETKKWGQAHMQARFAILKVLLEAGDaGFVKLEETKDED--SDLTIRLDRSKILTVGKPAIGDFLLKLQ 475

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1831506368 615 AYKSTGDFEGGKRLFESYGVVGDTELHWRDICIARRKPRRLFVQPNTV-EKNGEISLVTYSSDVSGVIQSFVERY 688
Cdd:pfam03571 476 VYKSTADVEAGTEFYEDYTTVDEEFLKWRDIVLAKKQPRKVFVQANTVlNDGGKVELKEYEETPEGMIQSFVERF 550
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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