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Conserved domains on  [gi|1831514711|ref|NP_001367272|]
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CXXC-type zinc finger protein 1 [Caenorhabditis elegans]

Protein Classification

CpG_bind_C superfamily-containing protein( domain architecture ID 40203)

CpG_bind_C superfamily-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CpG_bind_C super family cl13675
CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that ...
 2-125 1.36e-48

CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that exhibits a DNA binding specificity for unmethylated CpG motifs. CpG is made of a PHD1, an acidic, a basic, a coiled-coil, and a PHD2 domains. This protein contains three cysteine-rich domains identified at the N-terminal, central region and C-terminal of the protein, where the central cysteine-rich domain is located within the DNA-binding domain, found between PHD1 and the acidic domains. This domain is found in eukaryotes, and is approximately 240 amino acids in length. It is found at the C-terminal of the CpG-binding protein containing the coiled-coil and PHD2 domains.


The actual alignment was detected with superfamily member pfam12269:

Pssm-ID: 463514  Cd Length: 235  Bit Score: 158.23  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514711   2 FYCEKYDSRTNSFCKRLKSLCPEHRKLGDEQHLKVCGYPKkwedgmietaktvseLIEMEDPFGEEgCRTKKDACHKHHK 81
Cdd:pfam12269 128 MFCDFYNPQQKTYCKRLKVLCPEHTKEPKIPDTEVCGCPL---------------VRNVFDPTGEF-CRAPKKKCVKHYC 191

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1831514711  82 WIPSLRGTIELEQACLFQKMYELCHEMHKLNAHAEWTTNALSIM 125
Cdd:pfam12269 192 WEKLRRAEIDLERVRQWLKLDELFEQERQIRTAMANRAGVLGLM 235
 
Name Accession Description Interval E-value
CpG_bind_C pfam12269
CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that ...
 2-125 1.36e-48

CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that exhibits a DNA binding specificity for unmethylated CpG motifs. CpG is made of a PHD1, an acidic, a basic, a coiled-coil, and a PHD2 domains. This protein contains three cysteine-rich domains identified at the N-terminal, central region and C-terminal of the protein, where the central cysteine-rich domain is located within the DNA-binding domain, found between PHD1 and the acidic domains. This domain is found in eukaryotes, and is approximately 240 amino acids in length. It is found at the C-terminal of the CpG-binding protein containing the coiled-coil and PHD2 domains.


Pssm-ID: 463514  Cd Length: 235  Bit Score: 158.23  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514711   2 FYCEKYDSRTNSFCKRLKSLCPEHRKLGDEQHLKVCGYPKkwedgmietaktvseLIEMEDPFGEEgCRTKKDACHKHHK 81
Cdd:pfam12269 128 MFCDFYNPQQKTYCKRLKVLCPEHTKEPKIPDTEVCGCPL---------------VRNVFDPTGEF-CRAPKKKCVKHYC 191

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1831514711  82 WIPSLRGTIELEQACLFQKMYELCHEMHKLNAHAEWTTNALSIM 125
Cdd:pfam12269 192 WEKLRRAEIDLERVRQWLKLDELFEQERQIRTAMANRAGVLGLM 235
 
Name Accession Description Interval E-value
CpG_bind_C pfam12269
CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that ...
 2-125 1.36e-48

CpG binding protein C-terminal domain; CpG-binding protein is a transcriptional activator that exhibits a DNA binding specificity for unmethylated CpG motifs. CpG is made of a PHD1, an acidic, a basic, a coiled-coil, and a PHD2 domains. This protein contains three cysteine-rich domains identified at the N-terminal, central region and C-terminal of the protein, where the central cysteine-rich domain is located within the DNA-binding domain, found between PHD1 and the acidic domains. This domain is found in eukaryotes, and is approximately 240 amino acids in length. It is found at the C-terminal of the CpG-binding protein containing the coiled-coil and PHD2 domains.


Pssm-ID: 463514  Cd Length: 235  Bit Score: 158.23  E-value: 1.36e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514711   2 FYCEKYDSRTNSFCKRLKSLCPEHRKLGDEQHLKVCGYPKkwedgmietaktvseLIEMEDPFGEEgCRTKKDACHKHHK 81
Cdd:pfam12269 128 MFCDFYNPQQKTYCKRLKVLCPEHTKEPKIPDTEVCGCPL---------------VRNVFDPTGEF-CRAPKKKCVKHYC 191

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1831514711  82 WIPSLRGTIELEQACLFQKMYELCHEMHKLNAHAEWTTNALSIM 125
Cdd:pfam12269 192 WEKLRRAEIDLERVRQWLKLDELFEQERQIRTAMANRAGVLGLM 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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