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Conserved domains on  [gi|1831520145|ref|NP_001367832|]
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Class II aldolase/adducin N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

class II aldolase/adducin head domain-containing protein( domain architecture ID 842)

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations

Gene Symbol:  ADD3
PubMed:  10581174

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Aldolase_II super family cl00214
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 115-360 2.45e-63

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


The actual alignment was detected with superfamily member PRK07044:

Pssm-ID: 469663  Cd Length: 252  Bit Score: 211.25  E-value: 2.45e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 115 KYSKAERIQRNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLkaGV 194
Cdd:PRK07044    9 RVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDDSPY--PV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 195 NQPAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAM-VLGPVGYHDYQDIGDDDiqfDE---IIANLGD 270
Cdd:PRK07044   87 NPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALqFYGRLAYHDYEGIALDL---DEgerLVADLGD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 271 KNVLFLRNQGFLVVGDTIEHAtFLANNTVI-ACETQVrAARAGLDNLIIPEEKAIQRAFRNSRNTNSLKRngtvdwrvGE 349
Cdd:PRK07044  164 KPAMLLRNHGLLTVGRTVAEA-FLLMYTLErACEIQV-AAQAGGGELVLPPPEVAERTARQSLFDPGAGA--------GE 233

                         250
                  ....*....|.
gi 1831520145 350 LEWESWMRVLD 360
Cdd:PRK07044  234 LAWPALLRKLD 244
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 115-360 2.45e-63

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 211.25  E-value: 2.45e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 115 KYSKAERIQRNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLkaGV 194
Cdd:PRK07044    9 RVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDDSPY--PV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 195 NQPAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAM-VLGPVGYHDYQDIGDDDiqfDE---IIANLGD 270
Cdd:PRK07044   87 NPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALqFYGRLAYHDYEGIALDL---DEgerLVADLGD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 271 KNVLFLRNQGFLVVGDTIEHAtFLANNTVI-ACETQVrAARAGLDNLIIPEEKAIQRAFRNSRNTNSLKRngtvdwrvGE 349
Cdd:PRK07044  164 KPAMLLRNHGLLTVGRTVAEA-FLLMYTLErACEIQV-AAQAGGGELVLPPPEVAERTARQSLFDPGAGA--------GE 233

                         250
                  ....*....|.
gi 1831520145 350 LEWESWMRVLD 360
Cdd:PRK07044  234 LAWPALLRKLD 244
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 119-329 4.33e-45

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 160.38  E-value: 4.33e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 119 AERIQRNKLACLFRLADLFQWSQGIHNEISYRtnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDcGTLKagvNQPA 198
Cdd:COG0235     2 EEEELREELAAAGRRLARRGLVDGTAGNISVR--LDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVE-GDLK---PSSE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 199 FLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPL--CKEAMVLGPVGYHDYQDIGDDDIQfDEIIANLGDKNVLFL 276
Cdd:COG0235    76 TPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLeqTEAAAFLGDVPVVPYAGPGTEELA-EAIAEALGDRPAVLL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1831520145 277 RNQGFLVVGDTIEHAtflANNTVI---ACETQVRAARAGLDNLIIPEE-KAIQRAFR 329
Cdd:COG0235   155 RNHGVVVWGKDLAEA---FDRAEVleeAARIQLLALALGGPLVLSDEEiDKLARKFG 208
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 127-306 2.79e-39

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 143.16  E-value: 2.79e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145  127 LACLFRLADLFQWSQGIHNEISYRTnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtlKAGVNQPAFLLHSAIY 206
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGG--GGPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145  207 KAHPMVRCILHMHTAIVAAVASMKCGLLPLCKE---AMVLGPVGYHDYQDIGDDDIQFDEIIA-----NLGDKNVLFLRN 278
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKPLPLLPTEqaaAFLGGEIPYAPYAGPGTELAEEGAELAealaeALPDRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1831520145  279 QGFLVVGDTIEHATFLANNTVIACETQV 306
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 125-306 7.19e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 138.83  E-value: 7.19e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 125 NKLACLFRLADLFQWSQGIHNEISYRtnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtLKAGVnqpAFLLHSA 204
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVR--LPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG-LKPSS---ETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 205 IYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL--GPVGYHDYQDIGDDDIQfDEIIANLG-DKNVLFLRNQGF 281
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYTPGTEELG-ERIAEALGgDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1831520145 282 LVVGDTIEHATFLANNTVIACETQV 306
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 125-321 7.85e-33

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 125.94  E-value: 7.85e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 125 NKLACLFRLADLFQWSQGIHNEISYRtNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtlkagvnQPA--FLLH 202
Cdd:cd00398     5 RKIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGK-------KPSseTPLH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 203 SAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL---GPVGYHDYQDIGDDDiqfDEIIA--NLGDKN--VLF 275
Cdd:cd00398    77 LALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPETGE---DEIGTqrALGFPNskAVL 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1831520145 276 LRNQGFLVVGDTIEHATFLANNTVIACETQVRA-ARAGLDNLIIPEE 321
Cdd:cd00398   154 LRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKAlSMGGQLPPISLEL 200
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 115-360 2.45e-63

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 211.25  E-value: 2.45e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 115 KYSKAERIQRNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLkaGV 194
Cdd:PRK07044    9 RVSPAEWQARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVDDSPY--PV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 195 NQPAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAM-VLGPVGYHDYQDIGDDDiqfDE---IIANLGD 270
Cdd:PRK07044   87 NPAGFTIHSAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALqFYGRLAYHDYEGIALDL---DEgerLVADLGD 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 271 KNVLFLRNQGFLVVGDTIEHAtFLANNTVI-ACETQVrAARAGLDNLIIPEEKAIQRAFRNSRNTNSLKRngtvdwrvGE 349
Cdd:PRK07044  164 KPAMLLRNHGLLTVGRTVAEA-FLLMYTLErACEIQV-AAQAGGGELVLPPPEVAERTARQSLFDPGAGA--------GE 233

                         250
                  ....*....|.
gi 1831520145 350 LEWESWMRVLD 360
Cdd:PRK07044  234 LAWPALLRKLD 244
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 119-329 4.33e-45

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 160.38  E-value: 4.33e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 119 AERIQRNKLACLFRLADLFQWSQGIHNEISYRtnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDcGTLKagvNQPA 198
Cdd:COG0235     2 EEEELREELAAAGRRLARRGLVDGTAGNISVR--LDDDRFLITPSGVDFGELTPEDLVVVDLDGNVVE-GDLK---PSSE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 199 FLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPL--CKEAMVLGPVGYHDYQDIGDDDIQfDEIIANLGDKNVLFL 276
Cdd:COG0235    76 TPLHLAIYRARPDVGAVVHTHSPYATALSALGEPLPPLeqTEAAAFLGDVPVVPYAGPGTEELA-EAIAEALGDRPAVLL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1831520145 277 RNQGFLVVGDTIEHAtflANNTVI---ACETQVRAARAGLDNLIIPEE-KAIQRAFR 329
Cdd:COG0235   155 RNHGVVVWGKDLAEA---FDRAEVleeAARIQLLALALGGPLVLSDEEiDKLARKFG 208
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 127-306 2.79e-39

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 143.16  E-value: 2.79e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145  127 LACLFRLADLFQWSQGIHNEISYRTnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtlKAGVNQPAFLLHSAIY 206
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARV-GEEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGG--GGPKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145  207 KAHPMVRCILHMHTAIVAAVASMKCGLLPLCKE---AMVLGPVGYHDYQDIGDDDIQFDEIIA-----NLGDKNVLFLRN 278
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALGKPLPLLPTEqaaAFLGGEIPYAPYAGPGTELAEEGAELAealaeALPDRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1831520145  279 QGFLVVGDTIEHATFLANNTVIACETQV 306
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 125-306 7.19e-38

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 138.83  E-value: 7.19e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 125 NKLACLFRLADLFQWSQGIHNEISYRtnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtLKAGVnqpAFLLHSA 204
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVR--LPGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG-LKPSS---ETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 205 IYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL--GPVGYHDYQDIGDDDIQfDEIIANLG-DKNVLFLRNQGF 281
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYTPGTEELG-ERIAEALGgDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1831520145 282 LVVGDTIEHATFLANNTVIACETQV 306
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
PRK06661 PRK06661
hypothetical protein; Provisional
 121-359 3.55e-34

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 130.34  E-value: 3.55e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 121 RIQRNkLACLFRLADLFQWSQGIHNEISYRTNDEDnTFLMNPFGLLYHEITAATIVKIDENGKILDCGTLKagVNQPAFL 200
Cdd:PRK06661    2 DIKYN-LAAAYRIMAYLSLDDHTYTHLSARPKNAD-FYYIYPFGLRFEEVTTENLLKVSLDGQILEGEEYQ--YNKTGYF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 201 LHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAM-VLGPVGYHDYQDIG-DDDIQFDEIIANLGDKNVLFLRN 278
Cdd:PRK06661   78 IHGSIYKTRPDISAIFHYHTPASIAVSALKCGLLPISQWALhFYDRISYHNYNSLAlDADKQSSRLVNDLKQNYVMLLRN 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 279 QGFLVVGDTIEHATFLANNTVIACETQVRAARAGLDNLIIPEEKAIQRAFRNSRntnslkrngTVDWRVGELEWESWMRV 358
Cdd:PRK06661  158 HGAITCGKTIHEAMFYTYHLEQACKTQCLLNSTKKQELIIPSVEICKKTVKDLL---------SFEEDLGKRDWAAWLRL 228


                  .
gi 1831520145 359 L 359
Cdd:PRK06661  229 I 229
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 125-321 7.85e-33

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 125.94  E-value: 7.85e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 125 NKLACLFRLADLFQWSQGIHNEISYRtNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDCGtlkagvnQPA--FLLH 202
Cdd:cd00398     5 RKIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVEGK-------KPSseTPLH 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 203 SAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVL---GPVGYHDYQDIGDDDiqfDEIIA--NLGDKN--VLF 275
Cdd:cd00398    77 LALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPETGE---DEIGTqrALGFPNskAVL 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1831520145 276 LRNQGFLVVGDTIEHATFLANNTVIACETQVRA-ARAGLDNLIIPEE 321
Cdd:cd00398   154 LRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKAlSMGGQLPPISLEL 200
PRK06486 PRK06486
aldolase;
124-360 1.92e-26

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 109.03  E-value: 1.92e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 124 RNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILdcgtlkAGVNQP---AFL 200
Cdd:PRK06486   28 RVDLAACFRAAARHGLEEGICNHFSAVLPGHDDLFLVNPYGYAFSEITASDLLICDFDGNVL------AGRGEPeatAFF 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 201 LHSAIYKAHPMVRCILHMHTAIVAAVaSM--KCGLLPLCKEAM-VLGPVGY-HDYQDIGDDDIQFDEIIANLGDKNVLFL 276
Cdd:PRK06486  102 IHARIHRAIPRAKAAFHTHMPYATAL-SLteGRPLTTLGQTALkFYGRTAVdEDYNGLALDAAEGDRIARAMGDADIVFL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 277 RNQGFLVVGDTIEHA----TFLANntviACETQVRAARAGLDNLIIPEEKAiQRAFRNSRNTNSLKrngtvdwrvGELEW 352
Cdd:PRK06486  181 KNHGVMVCGPRIAEAwddlYYLER----ACEVQVLAMSTGRPLVPVDPAIA-AAVARQMREGDRES---------ARLHL 246


                  ....*...
gi 1831520145 353 ESWMRVLD 360
Cdd:PRK06486  247 EALRRTLD 254
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 124-312 5.76e-22

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 95.86  E-value: 5.76e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 124 RNKLACLFRLADLFQWSQGIHNEISYRTnDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDcGTlkaGVNQPAFLLHS 203
Cdd:PRK07090   32 RQKLALTCRILFDAGHDSGLAGQITARA-EAPGTYYTQRLGLGFDEITASNLLLVDEDLNVLD-GE---GMPNPANRFHS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 204 AIYKAHPMVRCILHMHTAIVAAVASMKcglLPLCKEAMVLGPVgyhdYQD-----------IGDDDiqfDEIIAN-LGDK 271
Cdd:PRK07090  107 WIYRARPDVNCIIHTHPPHVAALSMLE---VPLVVSHMDTCPL----YDDcaflkdwpgvpVGNEE---GEIISAaLGDK 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1831520145 272 NVLFLRNQGFLVVGDTIEHATFLANNTVIACETQVRAARAG 312
Cdd:PRK07090  177 RAILLSHHGQLVAGKSIEEACVLALLIERAARLQLLAMAAG 217
PRK06208 PRK06208
class II aldolase/adducin family protein;
118-320 4.23e-20

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 90.82  E-value: 4.23e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 118 KAERIQRN-KLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKILDcGtlKAGVNQ 196
Cdd:PRK06208   37 AEERLHRKqRLAAAFRLFARFGFDEGLAGHITARDPELPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVE-G--DRPLNR 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 197 PAFLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKEAMVLgpvgYHDYQDIGD------DDIQFDEIIANLGD 270
Cdd:PRK06208  114 AAFAIHSAIHEARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAF----YEDHALFDDftgvvvDTSEGRRIAAALGT 189

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1831520145 271 KNVLFLRNQGFLVVGDTIEHATF----LANntviACETQVRAARAGLDNLIIPE 320
Cdd:PRK06208  190 HKAVILQNHGLLTVGPSVDAAAWwfiaLER----ACQTQLLAEAAGPPQPIDHE 239
PRK07490 PRK07490
hypothetical protein; Provisional
 119-323 1.74e-17

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 82.46  E-value: 1.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 119 AERIQRNKLACLFRLADLFQWSQGIHNEISYRTNDEDNTFLMNPFGLLYHEITAATIVKIDENGKilDCGTLKAGVNQPA 198
Cdd:PRK07490    7 DEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLDADDP--STAERPDVPDATA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 199 FLLHSAIYKAHPMVRCILHMHTAIVAAVASMKCGLLPLCKE--AMVLGPVGYhdyqDIGDDDIQFDEIIAN----LGDKN 272
Cdd:PRK07490   85 WAIHGQIHRRLPHARCVMHVHSVYATALACLADPTLPPIDQntARFFNRVAV----DTLYGGMALEEEGERlaglLGDKR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1831520145 273 VLFLRNQGFLVVGDTIEHA-----TFLAnntviACETQVRAARAGLDNLIIPEEKA 323
Cdd:PRK07490  161 RLLMGNHGVLVTGDTVAEAfddlyYFER-----ACQTYITALSTGQPLRVLSDAVA 211
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 136-291 1.94e-08

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 55.40  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 136 LFQWSQGihnEISYRTNDEDnTFLMNPFGLLYHEITAATIVKIDENGKILDcGTLKAGVNQPAfllHSAIYKAHPMVRCI 215
Cdd:PRK06557   27 LVVWTSG---NVSARDPGTD-LVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-GDLKPSSDTAS---HLYVYRHMPDVGGV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 216 LHMH----TAIVAAVASMKCGLLPLCKEamvLG---PVGyhDYQDIGDDDI--QFDEIIANLGDKNVLfLRNQGFLVVGD 286
Cdd:PRK06557   99 VHTHstyaTAWAARGEPIPCVLTAMADE---FGgpiPVG--PFALIGDEAIgkGIVETLKGGRSPAVL-MQNHGVFTIGK 172


                  ....*
gi 1831520145 287 TIEHA 291
Cdd:PRK06557  173 DAEDA 177
PRK08130 PRK08130
putative aldolase; Validated
 147-293 5.87e-06

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 47.95  E-value: 5.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 147 ISYRTndEDNTFLMNPFGLLYHEITAATIVKIDENGKILdcgtlkAGvNQPA--FLLHSAIYKAHPMVRCILHMHTAIVA 224
Cdd:PRK08130   30 ISARL--DDGGWLVTPTGSCLGRLDPARLSKVDADGNWL------SG-DKPSkeVPLHRAIYRNNPECGAVVHLHSTHLT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 225 AVAS------------------MKCGLLPLckeamvlgpVGYHdyqDIGDDDIQfdEIIANLGDKN--VLfLRNQGFLVV 284
Cdd:PRK08130  101 ALSClggldptnvlppftpyyvMRVGHVPL---------IPYY---RPGDPAIA--EALAGLAARYraVL-LANHGPVVW 165


                  ....*....
gi 1831520145 285 GDTIEHATF 293
Cdd:PRK08130  166 GSSLEAAVN 174
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
141-227 9.66e-04

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 41.26  E-value: 9.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 141 QGIHNEISYRTNDednTFLMNPFGLLYHEITAATIVKIDENGKiLDCGTLKAGvnqpAFLLHSAIYKAHPMVRCILHMHT 220
Cdd:PRK08087   24 QGTAGNVSVRYQD---GMLITPTGIPYEKLTESHIVFVDGNGK-HEEGKLPSS----EWRFHMAAYQTRPDANAVVHNHA 95


                  ....*..
gi 1831520145 221 AIVAAVA 227
Cdd:PRK08087   96 VHCTAVS 102
PRK06357 PRK06357
hypothetical protein; Provisional
 147-292 2.46e-03

hypothetical protein; Provisional


Pssm-ID: 180541 [Multi-domain]  Cd Length: 216  Bit Score: 40.14  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 147 ISYRTNDEDNT--FLMNPFGL---LYHEITAATIVKID-ENGKILD-CGTLKAGVNqpaflLHSAIYKAHPMVRCILHMH 219
Cdd:PRK06357   30 ISVRMTAEKNKeyIIMTPTLMseaKLCDLSPYQILVVDlNTGEVIEgVGRVTREIN-----MHEAAYVANPKIKCVYHSH 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831520145 220 T--AIVAAVASMKcglLPLCKEAMV-LGPVGYHDYQDIGDDDI--QFDEIIANLGDK---NVLFLRNQGFLVVGDTIEHA 291
Cdd:PRK06357  105 AkeSMFWATLGLE---MPNLTEATQkLGKIPTLPFAPATSPELaeIVRKHLIELGDKavpSAFLLNSHGIVITDTSLHKA 181


                  .
gi 1831520145 292 T 292
Cdd:PRK06357  182 Y 182
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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