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Conserved domains on  [gi|1831514340|ref|NP_001368475|]
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Collagen triple helix repeat protein [Caenorhabditis elegans]

Protein Classification

collagen-like domain-containing protein( domain architecture ID 1903237)

collagen-like domain-containing protein such as collagens, which are extracellular structural proteins involved in formation of connective tissue structure

PubMed:  21421911|15837519

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 52-213 2.68e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.47  E-value: 2.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  52 EDGDHGLVGEDGTPGADGNLGVPLSANgcivcPAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPG 131
Cdd:NF038329  139 DRGETGPAGPAGPPGPQGERGEKGPAG-----PQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAG 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340 132 RPGNDGRPGAPGAPGTRSVGRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAAGQPG 211
Cdd:NF038329  214 PDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNG 293


                  ..
gi 1831514340 212 GD 213
Cdd:NF038329  294 KD 295
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 52-213 2.68e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.47  E-value: 2.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  52 EDGDHGLVGEDGTPGADGNLGVPLSANgcivcPAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPG 131
Cdd:NF038329  139 DRGETGPAGPAGPPGPQGERGEKGPAG-----PQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAG 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340 132 RPGNDGRPGAPGAPGTRSVGRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAAGQPG 211
Cdd:NF038329  214 PDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNG 293


                  ..
gi 1831514340 212 GD 213
Cdd:NF038329  294 KD 295
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-213 1.83e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.75  E-value: 1.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  84 PAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGAPGTRsvGRPGTAGSPGPQG 163
Cdd:NF038329  124 PAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPA--GEKGPQGPRGETG 201

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1831514340 164 PPGQNGNDGQPGNDGAPGQPGQPGPDGHPG--QPGNAGPPGTPGAAGQPGGD 213
Cdd:NF038329  202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPGPTGEDGPQGPD 253
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-218 3.34e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340 103 DGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGAPGtrSVGRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQ 182
Cdd:NF038329  116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERG--EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGP 193

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1831514340 183 PGQPGPDGHPGQPGNAGPPGTPGAAGQPGGDAAYCP 218
Cdd:NF038329  194 QGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGP 229
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 172-211 1.62e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 38.63  E-value: 1.62e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1831514340 172 GQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAAGQPG 211
Cdd:pfam01391  16 GPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 5-224 7.27e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340   5 PQGGKQRQVYESLFGRTKRQAAQCNCGANSAASNCPAGPPGPPGAPGEDGDHGLVGEDGTPGADGNLGVP--LSANGciv 82
Cdd:NF038329  187 PAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAgkDGPRG--- 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  83 cPAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGapgtrsvgrpgtagspgpq 162
Cdd:NF038329  264 -DRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPG------------------- 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1831514340 163 gppgqngNDGQPGNDGAPGQPGQPGPDGH--PGQPGNAgpPGTPGAAGQPGGDAAYCPCPSRSS 224
Cdd:NF038329  324 -------KDGLPGKDGKDGQPGKPAPKTPevPQKPDTA--PHTPKTPQIPGQSKDVTPAPQNPS 378
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 52-213 2.68e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.47  E-value: 2.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  52 EDGDHGLVGEDGTPGADGNLGVPLSANgcivcPAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPG 131
Cdd:NF038329  139 DRGETGPAGPAGPPGPQGERGEKGPAG-----PQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAG 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340 132 RPGNDGRPGAPGAPGTRSVGRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAAGQPG 211
Cdd:NF038329  214 PDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNG 293


                  ..
gi 1831514340 212 GD 213
Cdd:NF038329  294 KD 295
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-213 1.83e-06

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 48.75  E-value: 1.83e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  84 PAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGAPGTRsvGRPGTAGSPGPQG 163
Cdd:NF038329  124 PAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPA--GEKGPQGPRGETG 201

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1831514340 164 PPGQNGNDGQPGNDGAPGQPGQPGPDGHPG--QPGNAGPPGTPGAAGQPGGD 213
Cdd:NF038329  202 PAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPGPTGEDGPQGPD 253
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 103-218 3.34e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 44.90  E-value: 3.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340 103 DGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGAPGtrSVGRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQ 182
Cdd:NF038329  116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERG--EKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGP 193

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1831514340 183 PGQPGPDGHPGQPGNAGPPGTPGAAGQPGGDAAYCP 218
Cdd:NF038329  194 QGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGP 229
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 172-211 1.62e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 38.63  E-value: 1.62e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1831514340 172 GQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAAGQPG 211
Cdd:pfam01391  16 GPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 151-207 6.76e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.09  E-value: 6.76e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1831514340 151 GRPGTAGSPGPQGPPGQNGNDGQPGNDGAPGQPGQPGPDGHPGQPGNAGPPGTPGAA 207
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 5-224 7.27e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340   5 PQGGKQRQVYESLFGRTKRQAAQCNCGANSAASNCPAGPPGPPGAPGEDGDHGLVGEDGTPGADGNLGVP--LSANGciv 82
Cdd:NF038329  187 PAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAgkDGPRG--- 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1831514340  83 cPAGPPGPPGQPGQNGQRGSDGQPGQDAMGGGQGAPGPQGPAGDNGQPGRPGNDGRPGAPGapgtrsvgrpgtagspgpq 162
Cdd:NF038329  264 -DRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPG------------------- 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1831514340 163 gppgqngNDGQPGNDGAPGQPGQPGPDGH--PGQPGNAgpPGTPGAAGQPGGDAAYCPCPSRSS 224
Cdd:NF038329  324 -------KDGLPGKDGKDGQPGKPAPKTPevPQKPDTA--PHTPKTPQIPGQSKDVTPAPQNPS 378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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