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Conserved domains on  [gi|1834199290|ref|NP_001368962|]
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cytoplasmic linker protein 190, isoform W [Drosophila melanogaster]

Protein Classification

CAP-Gly domain-containing linker protein; CAP-Gly domain-containing linker protein; CAP-Gly domain-containing protein( domain architecture ID 13652438)

CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth; CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth; cytoskeleton-associated protein (CAP)-Gly domain-containing protein similar to Saccharomyces cerevisiae nuclear fusion protein BIK1, a protein required for microtubule function during mating and mitosis

Gene Ontology:  GO:0031122|GO:0008017
PubMed:  15928712|12221106|18835717

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 1.06e-33

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 1.06e-33
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290  239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 743-1596 1.59e-30

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 132.10  E-value: 1.59e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  743 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 822
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  823 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 902
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  903 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 979
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 1059
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1119
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1120 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1197
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1198 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1277
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1357
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1358 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1430
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1571
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 1834199290 1572 GNEFDTQLAEYQKVIDEMDDAASVK 1596
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.84e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.84e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 546-912 6.72e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 6.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  546 DELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpsddgalqEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRE 625
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEEL------------EQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  626 NVKYLNEQIATLQSELVSKDEALEKFSLSECGIEnlrrELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLK 705
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  706 ATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADssalddmlrlqkegTEEKSTLLEKTEKEL 785
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE--------------LEALLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  786 VQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELedfqkkQSESEVHLQEI 865
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEE-------LREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEA 956

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290  866 KAQNTQKDFELVESGESLKKLQQQLEQktLGHEKLqAALEELKKEKE 912
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKRLENKIKE--LGPVNL-AAIEEYEELKE 1000
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1773-1789 1.39e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.39e-06
                           10
                   ....*....|....*..
gi 1834199290 1773 RKYCDSCEVFGHDTSEC 1789
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1726-1743 1.01e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 1.01e-04
                           10
                   ....*....|....*...
gi 1834199290 1726 RLFCDICDEFDqHDTEDC 1743
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 super family cl25907
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1534-1703 3.01e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


The actual alignment was detected with superfamily member COG4913:

Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1534 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1608
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1609 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1688
Cdd:COG4913    299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                          170
                   ....*....|....*
gi 1834199290 1689 QQKNDALKAKVQTLE 1703
Cdd:COG4913    358 ERRRARLEALLAALG 372
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 2-118 1.58e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290    2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307   280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1834199290   82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307   354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 1.06e-33

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 1.06e-33
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290  239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 743-1596 1.59e-30

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 132.10  E-value: 1.59e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  743 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 822
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  823 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 902
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  903 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 979
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 1059
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1119
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1120 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1197
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1198 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1277
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1357
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1358 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1430
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1571
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 1834199290 1572 GNEFDTQLAEYQKVIDEMDDAASVK 1596
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.84e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.84e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 239-307 2.84e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.84e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290   239 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 307
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1273-1624 1.22e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.22e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1273 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1347
Cdd:COG1196    213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1348 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1427
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1428 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1507
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1508 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1587
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1834199290 1588 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1624
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 125-190 3.69e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.69e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290   125 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 190
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 772-1645 1.86e-20

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 98.89  E-value: 1.86e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  772 EEKSTLLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDLKQLA-EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 849
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALeYYQLKEKLELEEEYLLYlDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  850 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 929
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  930 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 1009
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1010 SGHLLEQITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 1089
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEE-------ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1090 SSSALhtklskfsdeiatghkeltskadawsQEMLQKEKELQELRQQLQDSQDSQTKLKAegerkeKSFEESIKNLQEEV 1169
Cdd:pfam02463  491 SRQKL--------------------------EERSQKESKARSGLKVLLALIKDGVGGRI------ISAHGRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1170 TKAKTENL-ELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQA 1248
Cdd:pfam02463  539 ENYKVAIStAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1249 EKSETNHIFELFEMEADMNSERLIEKVTGIKE--ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE 1326
Cdd:pfam02463  619 DKRAKVVEGILKDTELTKLKESAKAKESGLRKgvSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1327 IQQSLQELqdsvKQKEELVQNLEEKVResssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG 1406
Cdd:pfam02463  699 LEIKKKEQ----REKEELKKLKLEAEE-----LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1407 ELQQVQEANGDIKDSLVKVEELvkvLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANG 1486
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEE---KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1487 ELKEALCQKENGLKELQGKLDESNtvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQ 1566
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQ--ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1567 LLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSRE 1645
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
996-1618 1.59e-19

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 95.88  E-value: 1.59e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  996 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 1070
Cdd:PRK02224   182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1071 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 1141
Cdd:PRK02224   258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1142 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1221
Cdd:PRK02224   337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1222 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1289
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1290 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1369
Cdd:PRK02224   471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1370 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1449
Cdd:PRK02224   542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1450 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1529
Cdd:PRK02224   594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1530 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1603
Cdd:PRK02224   651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                          650
                   ....*....|....*
gi 1834199290 1604 QNRVAELETALRQAN 1618
Cdd:PRK02224   721 ESMYGDLRAELRQRN 735
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 237-301 6.61e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.40  E-value: 6.61e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  237 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV 301
Cdd:COG5244      4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFI 64
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 546-912 6.72e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 6.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  546 DELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpsddgalqEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRE 625
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEEL------------EQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  626 NVKYLNEQIATLQSELVSKDEALEKFSLSECGIEnlrrELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLK 705
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  706 ATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADssalddmlrlqkegTEEKSTLLEKTEKEL 785
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE--------------LEALLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  786 VQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELedfqkkQSESEVHLQEI 865
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEE-------LREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEA 956

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290  866 KAQNTQKDFELVESGESLKKLQQQLEQktLGHEKLqAALEELKKEKE 912
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKRLENKIKE--LGPVNL-AAIEEYEELKE 1000
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 125-185 9.37e-09

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 60.47  E-value: 9.37e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290  125 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 185
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 592-875 2.66e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.51  E-value: 2.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  592 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 671
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  672 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 750
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  751 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 830
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1834199290  831 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 875
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
613-860 7.90e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.25  E-value: 7.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  613 IAEQLEEEQ-RLRENVKYLNEQIATLQSELVSKDEALEKFsLSECGIENlrrelellkeenekqAQEAQAEFTRKLAEKS 691
Cdd:COG3206    162 LEQNLELRReEARKALEFLEEQLPELRKELEEAEAALEEF-RQKNGLVD---------------LSEEAKLLLQQLSELE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  692 VEVLRLSSELQNLKATSDSLESERVNKTDECEILQTevrmrDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEg 770
Cdd:COG3206    226 SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNHpDVIALRAQ- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  771 teekstlLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDL-KQLAEQEKLVREMtenaiNQIQLEKESIEQQLALKQNEL 848
Cdd:COG3206    300 -------IAALRAQLQQEAQRILASLeAELEALQAREASLqAQLAQLEARLAEL-----PELEAELRRLEREVEVARELY 367

                          250
                   ....*....|..
gi 1834199290  849 EDFQKKQSESEV 860
Cdd:COG3206    368 ESLLQRLEEARL 379
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1773-1789 1.39e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.39e-06
                           10
                   ....*....|....*..
gi 1834199290 1773 RKYCDSCEVFGHDTSEC 1789
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK11281 PRK11281
mechanosensitive channel MscK;
519-929 1.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  519 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 592
Cdd:PRK11281    40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 663
Cdd:PRK11281   101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  664 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 743
Cdd:PRK11281   157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  744 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 802
Cdd:PRK11281   215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  803 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 857
Cdd:PRK11281   285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  858 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 923
Cdd:PRK11281   365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                   ....*.
gi 1834199290  924 QLQSKS 929
Cdd:PRK11281   439 QLLSVS 444
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1726-1743 1.01e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 1.01e-04
                           10
                   ....*....|....*...
gi 1834199290 1726 RLFCDICDEFDqHDTEDC 1743
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1534-1703 3.01e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1534 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1608
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1609 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1688
Cdd:COG4913    299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                          170
                   ....*....|....*
gi 1834199290 1689 QQKNDALKAKVQTLE 1703
Cdd:COG4913    358 ERRRARLEALLAALG 372
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1302-1450 4.63e-04

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 43.56  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1302 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1381
Cdd:cd21116     74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1382 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1450
Cdd:cd21116    151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 736-1116 4.68e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.00  E-value: 4.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  736 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 814
Cdd:NF033838    71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  815 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 892
Cdd:NF033838   144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  893 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 972
Cdd:NF033838   216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  973 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 1050
Cdd:NF033838   289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1051 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 1116
Cdd:NF033838   354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1326-1553 7.17e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.85  E-value: 7.17e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  1326 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1399
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  1400 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1479
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290  1480 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1553
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-118 1.58e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290    2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307   280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1834199290   82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307   354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
SHE3 pfam17078
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an ...
 1502-1702 6.67e-03

SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an RNA-binding protein that binds specific mRNAs, including the mRNA of Ash1, which is invalid in cell-fate determination. She3 acts as an adapter protein that docks the myosin motor Myo4p onto an Ash1-She2p ribonucleoprotein complex. She3 seems to bind to Myo4p and Shep2p via different domains.


Pssm-ID: 293683 [Multi-domain]  Cd Length: 228  Bit Score: 40.11  E-value: 6.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1502 LQGKLDESNTVLESQKKSHNEIQDKLEQAQQKErtlqeetSKLAEQLSQLKQANEELQKSLQQKQlllEKGNEFDTQLAE 1581
Cdd:pfam17078    8 LHDQIDALTKTNLQLTVQSQNLLSKLEIAQQKE-------SKFLENLASLKHENDNLSSMLNRKE---RRLKDLEDQLSE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1582 YQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAnDAQKTAYLETKELRRQLESLELEKSREVL-SLKAQMNGASSRS 1660
Cdd:pfam17078   78 LKNSYEELTESNKQLKKRLENSSASETTLEAELERL-QIQYDALVDSQNEYKDHYQQEINTLQESLeDLKLENEKQLENY 156

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1661 GKGDEVESLDIETslaKINFLNSIIADMQQKNDALKAKVQTL 1702
Cdd:pfam17078  157 QQRISSNDKDIDT---KLDSYNNKFKNLDNIYVNKNNKLLTK 195
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 239-306 1.06e-33

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.44  E-value: 1.06e-33
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290  239 VGDRVIVSsgfGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKV 306
Cdd:pfam01302    1 VGDRVEVP---GGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 743-1596 1.59e-30

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 132.10  E-value: 1.59e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  743 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEklvrem 822
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK------ 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  823 tenaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQA 902
Cdd:TIGR02168  269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  903 ALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQ 979
Cdd:TIGR02168  345 KLEELKEELESLeaeLEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 1059
Cdd:TIGR02168  407 ARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRA----------EASDLQDKVKE----------ITDTLHAELQAERSSSSALHTKLSKFSDEIATghkelTSKADAW 1119
Cdd:TIGR02168  485 AQLQArldslerlqeNLEGFSEGVKAllknqsglsgILGVLSELISVDEGYEAAIEAALGGRLQAVVV-----ENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1120 SQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEEVTKAKTeNLELSTGTQTTIKDLQERLEIT 1197
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKniEGFLGVAKDLVKFDPKLRK-ALSYLLGGVLVVDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1198 NaELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELstvlevlqaeksetnhifelfemeadmnsERLIEKVTG 1277
Cdd:TIGR02168  639 K-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREI-----------------------------EELEEKIEE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1357
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1358 IIEAQNTKLNESNVQLENKTSCLKETQDQ-------LLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1430
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEElkalreaLDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TVLESQKKSHNEIQDKL--------EQAQQKERTLQEETSKLAEQLSQLKQ-----------ANEELQKSLQQKQLLLEK 1571
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|....*
gi 1834199290 1572 GNEFDTQLAEYQKVIDEMDDAASVK 1596
Cdd:TIGR02168 1009 KEDLTEAKETLEEAIEEIDREARER 1033
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 125-189 6.84e-30

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 113.27  E-value: 6.84e-30
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  125 IGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRL 189
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 239-307 2.84e-29

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 111.91  E-value: 2.84e-29
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290   239 VGDRVIVSSGfgSRPGILRYLGETQFAPGNWCGVELDEP-SGKNDGTVDDIRYFECKPKYGVFVPIAKVS 307
Cdd:smart01052    1 VGDRVEVGGG--GRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 734-1535 4.00e-27

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 120.94  E-value: 4.00e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  734 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE----QLEKQISDL 809
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEeeleKLTEEISEL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  810 KQ--------LAEQEKLVREMTENAINQIQ-------LEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQntqkdf 874
Cdd:TIGR02169  264 EKrleeieqlLEELNKKIKDLGEEEQLRVKekigeleAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAE------ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  875 elvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIikekEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASG 954
Cdd:TIGR02169  338 --------IEELEREIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  955 EEGSK---TVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAAL 1031
Cdd:TIGR02169  406 RELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1032 SSchtdvesKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsdEIATGH-- 1109
Cdd:TIGR02169  486 SK-------LQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAI---------EVAAGNrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1110 KELTSKADAWSQEMLQKEKELQELRQ------QLQDSQDSQTKLKAEG------------ERKEKSFE---------ESI 1162
Cdd:TIGR02169  550 NNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEDGvigfavdlvefdPKYEPAFKyvfgdtlvvEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1163 KNLQEEVTKAKTENLE---------------LSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1227
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEgelfeksgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1228 ANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSerLIEKVTGIKEELKETHLQLDERQKKFEELEEKL---- 1303
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLE--ELEEDLSS--LEQEIENVKSELKELEARIEELEEDLHKLEEALndle 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1304 --------KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLEN 1375
Cdd:TIGR02169  786 arlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1376 KTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1455
Cdd:TIGR02169  866 LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE 945

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1456 lLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDesntVLESQKKshnEIQDKLEQAQQKER 1535
Cdd:TIGR02169  946 -IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRA----KLEEERK---AILERIEEYEKKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 853-1647 2.08e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.15  E-value: 2.08e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  853 KKQSESEVHLQEIKAQNTQKDFELveSGESLKKLQQQLEQKtlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 932
Cdd:TIGR02168  206 ERQAEKAERYKELKAELRELELAL--LVLRLEELREELEEL----QEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  933 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGH 1012
Cdd:TIGR02168  280 EEEIEELQKELYAL-----------ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1013 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLhAELQAERSS-- 1090
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRR-ERLQQEIEEll 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1091 SSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKE--KSFEESIKNLQEE 1168
Cdd:TIGR02168  428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEG 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1169 VTKAKTENLELSTGTQTtikdLQERLEITNAELQHKEKMASEDAQKIadlktLVEAIQVANANISA---TNAELSTVLE- 1244
Cdd:TIGR02168  508 VKALLKNQSGLSGILGV----LSELISVDEGYEAAIEAALGGRLQAV-----VVENLNAAKKAIAFlkqNELGRVTFLPl 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1245 -VLQAEKSETNHIFELFEMEADMNSERLIEK------------------VTGIKEEL----------------------- 1282
Cdd:TIGR02168  579 dSIKGTEIQGNDREILKNIEGFLGVAKDLVKfdpklrkalsyllggvlvVDDLDNALelakklrpgyrivtldgdlvrpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1283 -------KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRES 1355
Cdd:TIGR02168  659 gvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1356 SSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEK 1435
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1436 LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLES 1515
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE-------LEALLNERASLEEALAL 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1516 QKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEfdtqlaEYQKVIDEMDDAASV 1595
Cdd:TIGR02168  892 LRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDN---LQERLSE------EYSLTLEEAEALENK 962

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1596 KSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE-----LEKSREVL 1647
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTaqkedLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 605-1564 2.66e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 2.66e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  605 QQKEVESRIAEQLEEEQRLRENVKYLNEQIATL--QSELVSK----DEALEKFSLSECGIE-NLRRELELLKEENEKQAQ 677
Cdd:TIGR02168  173 RRKETERKLERTRENLDRLEDILNELERQLKSLerQAEKAERykelKAELRELELALLVLRlEELREELEELQEELKEAE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  678 EAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLnvQKADS 757
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL--EELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  758 SALDDMLRLQKEGTEekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKlvremteNAINQIQLEKESI 837
Cdd:TIGR02168  331 KLDELAEELAELEEK-----LEELKEELESLEAELEELEAELEELESRLEELEEQLETLR-------SKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  838 eqqlalkQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESgeSLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKE 917
Cdd:TIGR02168  399 -------NNEIERLEARLERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  918 KEQELQQLQsksaesesalkvvqvqleqlqqqaaasgeegsktvaklhdeisQLKSQAEETQSELKSTQSNLEAKSKQLE 997
Cdd:TIGR02168  470 LEEAEQALD-------------------------------------------AAERELAQLQARLDSLERLQENLEGFSE 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  998 AANGSLEEEAKKSGHLLEQITKLKSEVGETQA---ALSSCHTDVESKTkqLEAANAALekvnkeyaESRAEASDLQDKVK 1074
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSELISVDEGYEAAieaALGGRLQAVVVEN--LNAAKKAI--------AFLKQNELGRVTFL 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1075 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEkELQElrqqlqdsqdsqtklkAEGERK 1154
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD-DLDN----------------ALELAK 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1155 EKSFEESIKNLQEE-------VTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQV 1227
Cdd:TIGR02168  640 KLRPGYRIVTLDGDlvrpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRK 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1228 ANANISATNAELSTVLEVLQAEksetnhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1307
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAE------------------VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1308 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL 1387
Cdd:TIGR02168  782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1388 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNL 1467
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1468 QG---ESLAVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESNTV-------LESQKKSHNEIQDKLEQAQQKERTL 1537
Cdd:TIGR02168  942 QErlsEEYSLTLEEAEALENKIEDDEEEARRR--LKRLENKIKELGPVnlaaieeYEELKERYDFLTAQKEDLTEAKETL 1019

                          970       980
                   ....*....|....*....|....*...
gi 1834199290 1538 QEETSKL-AEQLSQLKQANEELQKSLQQ 1564
Cdd:TIGR02168 1020 EEAIEEIdREARERFKDTFDQVNENFQR 1047
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 846-1647 1.13e-24

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 112.85  E-value: 1.13e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  846 NELEDFQKKQSESEVHLQEIKAQ--NTQKDFELVESGESLKKLQQQLEQKTLGHEKLqaALEELKKEKETIIKEKEQELQ 923
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQleRLRREREKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQLASLEEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  924 QLQSKSAESESALKVVQVQLEQLQQQAAASGEEgsktvaklhdEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSL 1003
Cdd:TIGR02169  255 KLTEEISELEKRLEEIEQLLEELNKKIKDLGEE----------EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1004 EEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQ---DKVKEITDTL 1080
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYReklEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1081 HAELQAERSSSSALHTKLSKFSDEIA---TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERkeks 1157
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNAAIAgieAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDR---- 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1158 FEESIKNLQEEVTKAKTENLELSTG------TQTTIKDLQERLEITNAEL-QHKEKMASE---------DAQKIADLKTL 1221
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEERvrggraVEEVLKASIQGVHGTVAQLgSVGERYATAievaagnrlNNVVVEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1222 VEAIQVANA---------------------NISATNAELSTVLEVLQAEKSETNHIFELF-------EMEAD---MNSER 1270
Cdd:TIGR02169  561 KEAIELLKRrkagratflplnkmrderrdlSILSEDGVIGFAVDLVEFDPKYEPAFKYVFgdtlvveDIEAArrlMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1271 LiekVTgIKEELKET-------HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSvkqkee 1343
Cdd:TIGR02169  641 M---VT-LEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE------ 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1344 lVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLv 1423
Cdd:TIGR02169  711 -LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL- 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1424 kveelvkvLEEKLQAATSQLDAQQATNKELQELLvksQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQ 1503
Cdd:TIGR02169  789 --------SHSRIPEIQAELSKLEEEVSRIEARL---REIEQKLN----RLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1504 GKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL----LLEKGNEFDTQL 1579
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlseLKAKLEALEEEL 933

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1580 AEYQKVIDEMDDaASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLesLELEKSREVL 1647
Cdd:TIGR02169  934 SEIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRL--DELKEKRAKL 998
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1273-1624 1.22e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.22e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1273 EKVTGIKEELKETH-----LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQN 1347
Cdd:COG1196    213 ERYRELKEELKELEaelllLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1348 LEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1427
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1428 LVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD 1507
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1508 ESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVID 1587
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 1834199290 1588 EMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1624
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA 569
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 125-190 3.69e-23

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 94.19  E-value: 3.69e-23
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290   125 IGQRVWLGGT-RPGQIAFIGDTHFAAGEWAGVVLDEPN-GKNDGCVSGKRYFQCEPKRGIFSRLTRLT 190
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 968-1647 3.33e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 104.63  E-value: 3.33e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  968 ISQLKSQAEETQSELKSTQSNLE-------AKSKQLEaangSLEEEAKKsghlLEQITKLKSEVGETQAALS-----SCH 1035
Cdd:COG1196    167 ISKYKERKEEAERKLEATEENLErledilgELERQLE----PLERQAEK----AERYRELKEELKELEAELLllklrELE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1036 TDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALhtklskfsDEIATGHKELTSK 1115
Cdd:COG1196    239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL--------ARLEQDIARLEER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1116 ADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLE 1195
Cdd:COG1196    311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1196 ITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSEtnhifELFEMEADMNSERLIEKV 1275
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA-----AEEEAELEEEEEALLELL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1276 TGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVkqkEELVQNLEEKVRES 1355
Cdd:COG1196    466 AELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV---LIGVEAAYEAALEA 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1356 SSIIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEK 1435
Cdd:COG1196    543 ALAAALQN-IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1436 LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvles 1515
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE------- 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1516 qkkshnEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASV 1595
Cdd:COG1196    695 ------LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE---EEELLEEEALEELPEPPDLEEL 765

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1596 KSAlLEQLQNRVAELET----ALRQAnDAQKTAYletKELRRQLEslELEKSREVL 1647
Cdd:COG1196    766 ERE-LERLEREIEALGPvnllAIEEY-EELEERY---DFLSEQRE--DLEEARETL 814
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 735-1315 2.93e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.93e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  735 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAE 814
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  815 QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKT 894
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  895 LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQ 974
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  975 AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVEskTKQLEAANAALEK 1054
Cdd:COG1196    473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE--AALEAALAAALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1055 VNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQkekELQELR 1134
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT---LLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1135 QQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT-KAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQ 1213
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTgGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1214 KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKEthL------ 1287
Cdd:COG1196    708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA--Lgpvnll 785

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1834199290 1288 ---QLDERQKKFEELEEKLKQAQQSEQKLQQ 1315
Cdd:COG1196    786 aieEYEELEERYDFLSEQREDLEEARETLEE 816
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 513-1195 6.48e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.52  E-value: 6.48e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  513 LKARIVELESALDNERKKTEELQCSIDEAQfcgDELNAQSQvykeKIHDLESKITKLVSATPSLQsilppdlpSDDGALQ 592
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALAN----EISRLEQQKQILRERLANLE--------RQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKMTIQQKE---VESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLK 669
Cdd:TIGR02168  323 AQLEELESKLDELAEElaeLEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  670 EENEKQAQEAQAEFTRKLAEKSVEVLRLSS-ELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTT 748
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  749 QLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEK---------ELVQSKEQAAKTL-------------NDKEQLEKQI 806
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvlsELISVDEGYEAAIeaalggrlqavvvENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  807 SDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI-----------KAQNTQK--- 872
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldNALELAKklr 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  873 --------DFELVESG------------------ESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQ 926
Cdd:TIGR02168  643 pgyrivtlDGDLVRPGgvitggsaktnssilerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  927 SKSAESeSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEE 1006
Cdd:TIGR02168  723 ELSRQI-SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1007 AKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQA 1086
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1087 ERSSSSALHTKLSKFSdeiatghkELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQ 1166
Cdd:TIGR02168  882 RASLEEALALLRSELE--------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL 953

                          730       740
                   ....*....|....*....|....*....
gi 1834199290 1167 EEVTKAKTENLELSTGTQTTIKDLQERLE 1195
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIK 982
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 772-1645 1.86e-20

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 98.89  E-value: 1.86e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  772 EEKSTLLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDLKQLA-EQEKLVREMTENAINQIQLEKESIEQQLALKQNELE 849
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALeYYQLKEKLELEEEYLLYlDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  850 DFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKeketiikeKEQELQQLQSKS 929
Cdd:pfam02463  266 KLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--------AEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  930 AESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 1009
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1010 SGHLLEQITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERS 1089
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEE-------ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1090 SSSALhtklskfsdeiatghkeltskadawsQEMLQKEKELQELRQQLQDSQDSQTKLKAegerkeKSFEESIKNLQEEV 1169
Cdd:pfam02463  491 SRQKL--------------------------EERSQKESKARSGLKVLLALIKDGVGGRI------ISAHGRLGDLGVAV 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1170 TKAKTENL-ELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQA 1248
Cdd:pfam02463  539 ENYKVAIStAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADED 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1249 EKSETNHIFELFEMEADMNSERLIEKVTGIKE--ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE 1326
Cdd:pfam02463  619 DKRAKVVEGILKDTELTKLKESAKAKESGLRKgvSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1327 IQQSLQELqdsvKQKEELVQNLEEKVResssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG 1406
Cdd:pfam02463  699 LEIKKKEQ----REKEELKKLKLEAEE-----LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1407 ELQQVQEANGDIKDSLVKVEELvkvLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANG 1486
Cdd:pfam02463  770 SLKEKELAEEREKTEKLKVEEE---KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1487 ELKEALCQKENGLKELQGKLDESNtvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQ 1566
Cdd:pfam02463  847 KLEKLAEEELERLEEEITKEELLQ--ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIK 924

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1567 LLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSRE 1645
Cdd:pfam02463  925 EEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
996-1618 1.59e-19

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 95.88  E-value: 1.59e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  996 LEAANGSLEE-----EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEkvnkEYAESRAEASDLQ 1070
Cdd:PRK02224   182 LSDQRGSLDQlkaqiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLE----EHEERREELETLE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1071 DKVKEITDTLhAELQAERSS-SSALHTK---LSKFSDEIA-----TGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ 1141
Cdd:PRK02224   258 AEIEDLRETI-AETEREREElAEEVRDLrerLEELEEERDdllaeAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1142 DSQTKLKAEGERkeksfeESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEitnaelqhkekmasedaqKIADLKTL 1221
Cdd:PRK02224   337 AQAHNEEAESLR------EDADDLEERAEELREEAAELESELEEAREAVEDRRE------------------EIEELEEE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1222 VEAIQVANANISATNAELSTVLEVLQAEKSETNHifELFEMEADMNSER-LIEKVTGIKEELK----------ETHLQ-L 1289
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELRE--REAELEATLRTAReRVEEAEALLEAGKcpecgqpvegSPHVEtI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1290 DERQKKFEELEEKLKQAQqseqklqqESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNEs 1369
Cdd:PRK02224   471 EEDRERVEELEAELEDLE--------EEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE- 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1370 nvqlenktsclketqdqllesqkkekqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAt 1449
Cdd:PRK02224   542 ---------------------------LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER- 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1450 nkeLQELLVKSQENEGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvlesqkkshneiqDKLEQ 1529
Cdd:PRK02224   594 ---IRTLLAAIADAEDEIE----RLREKREALAELNDERRERLAEKRERKRELEAEFDE----------------ARIEE 650

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1530 AQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSAL------LEQL 1603
Cdd:PRK02224   651 AREDKERAEEYLEQVEEKLDELREERDDLQAEI----------GAVENELEELEELRERREALENRVEALealydeAEEL 720

                          650
                   ....*....|....*
gi 1834199290 1604 QNRVAELETALRQAN 1618
Cdd:PRK02224   721 ESMYGDLRAELRQRN 735
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 608-1548 1.87e-19

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 95.63  E-value: 1.87e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  608 EVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEftRKL 687
Cdd:pfam01576   79 ELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE--RKL 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  688 AEKSVEvlRLSSELQNLKATSDSLEseRVNKTDECEILQTEVRMRDEQ-----IRELNQQLDEVTTQLNVQKADSSALDD 762
Cdd:pfam01576  157 LEERIS--EFTSNLAEEEEKAKSLS--KLKNKHEAMISDLEERLKKEEkgrqeLEKAKRKLEGESTDLQEQIAELQAQIA 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  763 MLRLQKEGTEEK-STLLEKTEKELVQsKEQAAKTLndkEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL 841
Cdd:pfam01576  233 ELRAQLAKKEEElQAALARLEEETAQ-KNNALKKI---RELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  842 --------------ALKQNELEDFQKKQSES----EVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEK---- 899
Cdd:pfam01576  309 edtldttaaqqelrSKREQEVTELKKALEEEtrshEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenae 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  900 LQAALEEL---KKEKETIIKEKEQELQQLQSKSAESESA---LKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKS 973
Cdd:pfam01576  389 LQAELRTLqqaKQDSEHKRKKLEGQLQELQARLSESERQraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  974 QAEETQSELKS---TQSNLEAKSKQLEAANGSL----EEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLE 1046
Cdd:pfam01576  469 QLQDTQELLQEetrQKLNLSTRLRQLEDERNSLqeqlEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1047 AANAALEKVNKEYAESRAEASDLQ---DKVKEITDTLHAELQAERSSSSALHTKLSKFSD------EIATGHKELTSKAD 1117
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLEktkNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQmlaeekAISARYAEERDRAE 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1118 AWSQE----MLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS----------FEESIKNLQEEVTKAKTENLELSTGT 1183
Cdd:pfam01576  629 AEAREketrALSLARALEEALEAKEELERTNKQLRAEMEDLVSSkddvgknvheLERSKRALEQQVEEMKTQLEELEDEL 708

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1184 QTTiKDLQERLEIT--------NAELQHKEKMASED----AQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKS 1251
Cdd:pfam01576  709 QAT-EDAKLRLEVNmqalkaqfERDLQARDEQGEEKrrqlVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQID 787

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1252 ETNHIFElfemEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1331
Cdd:pfam01576  788 AANKGRE----EAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQER 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1332 QELQDSV--------------KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCL--KETQDQLLES--QKK 1393
Cdd:pfam01576  864 DELADEIasgasgksalqdekRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELaaERSTSQKSESarQQL 943

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1394 EKQLQEEAAKLsgelqqvQEANGDIKDslvKVEELVKVLEEKLQAATSQLDaQQATNKELQELLVKSQENEgnLQGESLA 1473
Cdd:pfam01576  944 ERQNKELKAKL-------QEMEGTVKS---KFKSSIAALEAKIAQLEEQLE-QESRERQAANKLVRRTEKK--LKEVLLQ 1010

                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1474 VTEKLQQLEQangeLKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1548
Cdd:pfam01576 1011 VEDERRHADQ----YKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSKL 1081
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 697-1433 3.53e-19

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 94.32  E-value: 3.53e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  697 LSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKST 776
Cdd:TIGR04523   45 IKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEV 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  777 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 856
Cdd:TIGR04523  125 ELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  857 ESEVHLQEIKAQNTQkdfeLVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 936
Cdd:TIGR04523  205 NLKKKIQKNKSLESQ----ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNN 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  937 KVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEetQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 1016
Cdd:TIGR04523  281 KKI---------------KELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQ 343

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1017 ITKLKSEVGETQaalsschTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQdkvkeitdtlhaelqaerSSSSALHT 1096
Cdd:TIGR04523  344 ISQLKKELTNSE-------SENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE------------------SQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1097 KLSKFSDEiatgHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1176
Cdd:TIGR04523  399 KIQNQEKL----NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLS 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1177 LElstgtqttIKDLQERLEITNAELQHKEKMASEDAQKIADLKtlvEAIQVANANISatnaELSTVLEVLQAEKSETNHI 1256
Cdd:TIGR04523  475 RS--------INKIKQNLEQKQKELKSKEKELKKLNEEKKELE---EKVKDLTKKIS----SLKEKIEKLESEKKEKESK 539

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1257 F-----ELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSL 1331
Cdd:TIGR04523  540 IsdledELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1332 QELQDSVKQKEELVQNLE---EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQD---QLLESQKKEKQLQEEAAKLS 1405
Cdd:TIGR04523  620 EKAKKENEKLSSIIKNIKskkNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDdiiELMKDWLKELSLHYKKYITR 699

                          730       740       750
                   ....*....|....*....|....*....|..
gi 1834199290 1406 ----GELQQVQEANGDIKDSLVKVEELVKVLE 1433
Cdd:TIGR04523  700 miriKDLPKLEEKYKEIEKELKKLDEFSKELE 731
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 968-1709 1.47e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.47e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  968 ISQLKSQAEETQSELKSTQSNL---EAKSKQLEAANGSLEEEAKKSghllEQITKLKSEVGETQAALSschtdveskTKQ 1044
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLdrlEDILNELERQLKSLERQAEKA----ERYKELKAELRELELALL---------VLR 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1045 LEAANAALEKVNKEYAESRAEASDLQDKVKEiTDTLHAELQAErssssalHTKLSKFSDEIATGHKELTSKAdawsQEML 1124
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQE-LEEKLEELRLE-------VSELEEEIEELQKELYALANEI----SRLE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1125 QKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlelstgtqttIKDLQERLEITNAELQHK 1204
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEE-----------LESLEAELEELEAELEEL 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1205 EKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELK 1283
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1284 ETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE--- 1360
Cdd:TIGR02168  451 ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSElis 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1361 -------AQNTKLNES--NVQLENktsclKETQDQLLESQKKEKQ---------LQEEAAKLSGELQQVQEANG--DIKD 1420
Cdd:TIGR02168  531 vdegyeaAIEAALGGRlqAVVVEN-----LNAAKKAIAFLKQNELgrvtflpldSIKGTEIQGNDREILKNIEGflGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1421 SLVKV-EELVKVLE---------EKLQAATSQ------------LDAQQAT---------NKELQELLVKSQENEgNLQG 1469
Cdd:TIGR02168  606 DLVKFdPKLRKALSyllggvlvvDDLDNALELakklrpgyrivtLDGDLVRpggvitggsAKTNSSILERRREIE-ELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1470 ESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS----HNEIQDKLEQAQQKERTLQEETSKLA 1545
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDlarlEAEVEQLEERIAQLSKELTELEAEIE 764

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1546 EQLSQLKQANEELQKSLQQKQLLLEKGNEF-------DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAN 1618
Cdd:TIGR02168  765 ELEERLEEAEEELAEAEAEIEELEAQIEQLkeelkalREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLE 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1619 DAQKTAYLETKELRRQLESL-----ELEKSREVLS-LKAQMNGASSRSGKGDEVESLDIETSLAKINFLNsiiADMQQKN 1692
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELeelieELESELEALLnERASLEEALALLRSELEELSEELRELESKRSELR---RELEELR 921

                          810
                   ....*....|....*..
gi 1834199290 1693 DALKAKVQTLETLPMDF 1709
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRI 938
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 675-1508 6.66e-18

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 90.80  E-value: 6.66e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  675 QAQEAQAEFTRKLAEKSVEV-LRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQ 753
Cdd:pfam02463  205 QAKKALEYYQLKEKLELEEEyLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQ 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  754 KADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAInqiqLE 833
Cdd:pfam02463  285 EEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEE----EE 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  834 KESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEqktlGHEKLQAALEELKKEKET 913
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE----DLLKEEKKEELEILEEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  914 IIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKS 993
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALI 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  994 KQLEAANGSLEEEAKKSGHLLEQITKLKSEVgETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKV 1073
Cdd:pfam02463  517 KDGVGGRIISAHGRLGDLGVAVENYKVAIST-AVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIA 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1074 KEITDTLHAELQAERSSSSA----LHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKA 1149
Cdd:pfam02463  596 VLEIDPILNLAQLDKATLEAdeddKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1150 EGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVAN 1229
Cdd:pfam02463  676 LEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKS 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1230 ANISATN-AELSTVLEVLQAEKSETNHIFElfEMEADMNSERLIEKVTGIKEELKETHLQLdERQKKFEELEEKLKQAQQ 1308
Cdd:pfam02463  756 RLKKEEKeEEKSELSLKEKELAEEREKTEK--LKVEEEKEEKLKAQEEELRALEEELKEEA-ELLEEEQLLIEQEEKIKE 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1309 SEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLL 1388
Cdd:pfam02463  833 EELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLL 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1389 ESQKKEKQLQ--EEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGN 1466
Cdd:pfam02463  913 EEKENEIEERikEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNK 992

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1467 LQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1508
Cdd:pfam02463  993 DELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWN 1034
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 597-1426 8.72e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 86.95  E-value: 8.72e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  597 KLQEKMTIQQKEVESRIAEQLEEEQRLR-----------------ENVKYLNEQIATLQSELVSKDEALEKFSLSECGIE 659
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKlkeqakkaleyyqlkekLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  660 NLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIREL 739
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  740 NQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQlEKQISDLKQLAEQEKLV 819
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE-ELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  820 REMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEK 899
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  900 LQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQ 979
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 1059
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQD 1139
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1140 SQDSQTKL-----KAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQK 1214
Cdd:pfam02463  733 KINEELKLlkqkiDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKE 812

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1215 IADLKTLVEAIQVANANISatNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQK 1294
Cdd:pfam02463  813 EAELLEEEQLLIEQEEKIK--EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1295 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLE 1374
Cdd:pfam02463  891 KEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKE 970

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1375 NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVE 1426
Cdd:pfam02463  971 ELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1269-1649 1.66e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.14  E-value: 1.66e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1348
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1349 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1428
Cdd:COG1196    329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1429 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1508
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1509 SNTVLESQkkshneiqdkleQAQQKERTLQEETSKLAEQLSQLKQANEELqkslqqkQLLLEKGNEFDTQLAEY------ 1582
Cdd:COG1196    489 AAARLLLL------------LEAEADYEGFLEGVKAALLLAGLRGLAGAV-------AVLIGVEAAYEAALEAAlaaalq 549

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1583 QKVIDEMDDAASVKSALLEQLQNRVAELE-TALRQANDAQKTAYLETKELRRQLESLELEKSREVLSL 1649
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPlDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617
PTZ00121 PTZ00121
MAEBL; Provisional
 768-1544 2.65e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.58  E-value: 2.65e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  768 KEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE-QLEKQISDLKQLAEQEKlvremTENAiNQIQLEKESIEQQLALKQN 846
Cdd:PTZ00121  1121 KKKAEDARKAEEARKAEDARKAEEARKAEDAKRvEIARKAEDARKAEEARK-----AEDA-KKAEAARKAEEVRKAEELR 1194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  847 ELEDFQK----KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL-----EQKTLGHEKLQAALEELKKEKETIIKE 917
Cdd:PTZ00121  1195 KAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaeeERNNEEIRKFEEARMAHFARRQAAIKA 1274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  918 KE----QELQQLQS--KSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 991
Cdd:PTZ00121  1275 EEarkaDELKKAEEkkKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  992 KSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAE----AS 1067
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEekkkAD 1434

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1068 DLQDKVKEITDTLHAELQAE--RSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQT 1145
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEeaKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1146 KLKAEGERKE---KSFEESIKNLQ----EEVTKA----KTENLELSTGTQTTIKDLQERlEITNAELQHKEKMASEDAQK 1214
Cdd:PTZ00121  1515 AKKAEEAKKAdeaKKAEEAKKADEakkaEEKKKAdelkKAEELKKAEEKKKAEEAKKAE-EDKNMALRKAEEAKKAEEAR 1593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1215 IADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADmnSERLIEKVTGIKEELKETHLQLDERQK 1294
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE--EKKKAEELKKAEEENKIKAAEEAKKAE 1671

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1295 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE---KVRESSSIIEAQNTKLNESNV 1371
Cdd:PTZ00121  1672 EDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEnkiKAEEAKKEAEEDKKKAEEAKK 1751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1372 QLE--NKTSCLKETQDQLLESQKKEKQL---QEEAAKLSGELQQVQEANGDIKDSLVKVEE-------LVKVLEEKLQAA 1439
Cdd:PTZ00121  1752 DEEekKKIAHLKKEEEKKAEEIRKEKEAvieEELDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlVINDSKEMEDSA 1831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1440 TSQLDAQQATNKELQELLVKSQENEGNLQGESlAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1519
Cdd:PTZ00121  1832 IKEVADSKNMQLEEADAFEKHKFNKNNENGED-GNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGK 1910

                          810       820
                   ....*....|....*....|....*.
gi 1834199290 1520 HNE-IQDKLEQAQQKERTLQEETSKL 1544
Cdd:PTZ00121  1911 NNDiIDDKLDKDEYIKRDAEETREEI 1936
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 608-1195 3.61e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 3.61e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  608 EVESRI------AEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKfslsecgienlrrelellkeENEKQAQEAQA 681
Cdd:COG1196    197 ELERQLeplerqAEKAERYRELKEELKELEAELLLLKLRELEAELEELE--------------------AELEELEAELE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  682 EFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALD 761
Cdd:COG1196    257 ELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELE 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  762 DMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQL 841
Cdd:COG1196    337 EELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  842 ALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQE 921
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  922 LQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANG 1001
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1002 SLEEEAKKSGHLLEQITKLKSEVG--------ETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKV 1073
Cdd:COG1196    577 LPLDKIRARAALAAALARGAIGAAvdlvasdlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1074 KEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGER 1153
Cdd:COG1196    657 SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREE 736

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1154 KEKSFEESIKNLQEEVTKAKTENLELSTgTQTTIKDLQERLE 1195
Cdd:COG1196    737 LLEELLEEEELLEEEALEELPEPPDLEE-LERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1146-1695 6.71e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.83  E-value: 6.71e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1146 KLKAEGERKEK--SFEESIKNLQEEVTKAKTENLELS-TGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLV 1222
Cdd:COG1196    204 PLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1223 EAIQVANANISATNAELSTVLEVLQAEKSEtnhifelfemeADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEK 1302
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRE-----------LEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1303 LKQAqqsEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSC--- 1379
Cdd:COG1196    353 LEEA---EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELeea 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1380 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELL-- 1457
Cdd:COG1196    430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLeg 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1458 VKSQENEGNLQGESLA--------------------------VTEKLQQLEQANGELKEALCQKENGL---KELQGKLDE 1508
Cdd:COG1196    510 VKAALLLAGLRGLAGAvavligveaayeaaleaalaaalqniVVEDDEVAAAAIEYLKAAKAGRATFLpldKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1509 SNTVLESQKKSHNEIQDKLEQAQQKERTLQE---ETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKV 1585
Cdd:COG1196    590 AALARGAIGAAVDLVASDLREADARYYVLGDtllGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1586 IDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDE 1665
Cdd:COG1196    670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749

                          570       580       590
                   ....*....|....*....|....*....|
gi 1834199290 1666 VESLDIETSLAKINFLNSIIADMQQKNDAL 1695
Cdd:COG1196    750 EEALEELPEPPDLEELERELERLEREIEAL 779
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 675-1604 7.46e-16

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 83.94  E-value: 7.46e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  675 QAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQK 754
Cdd:TIGR00606  203 QEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQME 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  755 ADSSALDDMLRLQKEGTEEKSTLLE--------KTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENA 826
Cdd:TIGR00606  283 KDNSELELKMEKVFQGTDEQLNDLYhnhqrtvrEKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEH 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  827 INQIQLEKESIEQQLALKQNELEDFQKKQSESEVHL----QEIKAQNTQKDFELVESGESLKKlqqqlEQKTLGHEKLQA 902
Cdd:TIGR00606  363 IRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLvierQEDEAKTAAQLCADLQSKERLKQ-----EQADEIRDEKKG 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  903 ALEELKKEKETIIKEKEQ---ELQQLQSKSAESESALKVVQVQLEQLQQQAAAsgEEGSKTVAKLHDEISQLKSQAEETQ 979
Cdd:TIGR00606  438 LGRTIELKKEILEKKQEElkfVIKELQQLEGSSDRILELDQELRKAERELSKA--EKNSLTETLKKEVKSLQNEKADLDR 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNleAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDveskTKQLEAAnaaLEKVNKEY 1059
Cdd:TIGR00606  516 KLRKLDQEM--EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPN----KKQLEDW---LHSKSKEI 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRAEASDLQDKVKEITDTLHAELQAERSsssaLHTKLSKFSDEI--ATGHKELTSKADAWSQEMLQKEKELQELRQQL 1137
Cdd:TIGR00606  587 NQTRDRLAKLNKELASLEQNKNHINNELES----KEEQLSSYEDKLfdVCGSQDEESDLERLKEEIEKSSKQRAMLAGAT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1138 QDSQDSQTKLKAEgerkeksfEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIAD 1217
Cdd:TIGR00606  663 AVYSQFITQLTDE--------NQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1218 LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfEMEADMNSERLIEKVTGIKEELKEthlQLDERQKKFE 1297
Cdd:TIGR00606  735 RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG--TIMPEEESAKVCLTDVTIMERFQM---ELKDVERKIA 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1298 ELEEKLKQA--QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiieaqntklnesnvqlen 1375
Cdd:TIGR00606  810 QQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNE--------------------- 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1376 ktscLKETQDQLLESQKKEKQLQEEAAKLSGElqqVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQE 1455
Cdd:TIGR00606  869 ----LKSEKLQIGTNLQRRQQFEEQLVELSTE---VQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1456 LLVKSQENEGNLQGESLAVTEKLQQLEQangelkEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKER 1535
Cdd:TIGR00606  942 KVNDIKEKVKNIHGYMKDIENKIQDGKD------DYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQER 1015

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1536 TLQEETS--KLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtqlAEYQKVIDEMDDAASVKSALLEQLQ 1604
Cdd:TIGR00606 1016 WLQDNLTlrKRENELKEVEEELKQHLKEMGQMQVLQMK--------QEHQKLEENIDLIKRNHVLALGRQK 1078
PTZ00121 PTZ00121
MAEBL; Provisional
 610-1430 8.68e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 8.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  610 ESRIAEQLEEEQRLRENVKylneQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQ-AEFTRKLA 688
Cdd:PTZ00121  1086 DNRADEATEEAFGKAEEAK----KTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKrVEIARKAE 1161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  689 E-KSVEVLRLSSELQNLKATSDSLE---SERVNKTDEC----------------EILQTEVRMRDEQIR---------EL 739
Cdd:PTZ00121  1162 DaRKAEEARKAEDAKKAEAARKAEEvrkAEELRKAEDArkaeaarkaeeerkaeEARKAEDAKKAEAVKkaeeakkdaEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  740 NQQLDEVTTQLNVQKADSSALDDMLRLQKEG-TEEKSTLLEKTEKELVQSKEQAAKT--------LNDKEQLEKQISDLK 810
Cdd:PTZ00121  1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIkAEEARKADELKKAEEKKKADEAKKAeekkkadeAKKKAEEAKKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  811 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQ 888
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkKADAAKKKAEEKKKADEAKKKAE 1401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  889 QLEQKTLGHEKLQAA---LEELKKEKETIIKEKEQELQQLQSKSAES--ESALKVVQVQLEQLQQQAAASGEEGSKTvAK 963
Cdd:PTZ00121  1402 EDKKKADELKKAAAAkkkADEAKKKAEEKKKADEAKKKAEEAKKADEakKKAEEAKKAEEAKKKAEEAKKADEAKKK-AE 1480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  964 LHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGsleEEAKKSGHLLEQITKLKSEvgETQAALSSCHTDVESKTK 1043
Cdd:PTZ00121  1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA---EEAKKADEAKKAEEAKKAD--EAKKAEEKKKADELKKAE 1555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1044 QLEAANaalEKVNKEYAESRAEASDLQDKVKEITDTLHaelQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEM 1123
Cdd:PTZ00121  1556 ELKKAE---EKKKAEEAKKAEEDKNMALRKAEEAKKAE---EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAE 1629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1124 LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKnlqEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQH 1203
Cdd:PTZ00121  1630 EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKK---AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE 1706

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1204 KEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELK 1283
Cdd:PTZ00121  1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1284 EthlqldERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQN 1363
Cdd:PTZ00121  1787 E------EDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNEN 1860

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1364 TKLNESNVQLENKTSCLKETQDQLLESqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVK 1430
Cdd:PTZ00121  1861 GEDGNKEADFNKEKDLKEDDEEEIEEA-DEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIK 1926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1385-1703 1.49e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 1.49e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQLLESQKKE-KQLQEEAAKLSGELQQVQEANG---DIKDSLVKVEELVKVLEEKLQAATSQldAQQAtnKELQELlvKS 1460
Cdd:TIGR02168  147 SEIIEAKPEErRAIFEEAAGISKYKERRKETERkleRTRENLDRLEDILNELERQLKSLERQ--AEKA--ERYKEL--KA 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1461 QENEGNLQGESLAVTEKLQQLEQANGELKEA---LCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTL 1537
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAeeeLEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1538 QEETSKLAEQLSQL----KQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETA 1613
Cdd:TIGR02168  301 EQQKQILRERLANLerqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1614 LRQANDAQKTAYLETKELRRQLESLELEKSRevlSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKND 1693
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLER---LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                          330
                   ....*....|
gi 1834199290 1694 ALKAKVQTLE 1703
Cdd:TIGR02168  458 RLEEALEELR 467
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1121-1639 1.64e-15

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 82.38  E-value: 1.64e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1121 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEevTKAKTENLELS-TGTQTTIKDLQERLEITNA 1199
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYND--LKKQKEELENElNLLEKEKLNIQKNIDKIKN 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1200 ELQHKEKMASEDAQKIADLKTLVEAIqvanANISATNAELSTVLEVLQAEKSETNHIFElfemEADMNSERLIEKVTGIK 1279
Cdd:TIGR04523  195 KLLKLELLLSNLKKKIQKNKSLESQI----SELKKQNNQLKDNIEKKQQEINEKTTEIS----NTQTQLNQLKDEQNKIK 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1280 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtskeklteiQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1359
Cdd:TIGR04523  267 KQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1360 EAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1439
Cdd:TIGR04523  338 SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKL 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1440 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1519
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1520 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKgNEFDTQLAEYQKVIDEMDDAasvksal 1599
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKE------- 569

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 1834199290 1600 LEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1639
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKE 609
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 735-1639 3.15e-15

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 81.76  E-value: 3.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  735 QIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEK--TEKEL-VQSKEQAAKTLNDKEQLEKQISDLKQ 811
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQlqAETELcAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  812 LAEQEklvremtENAINQIQLEKESIEQQLAlkqneledfqkkqsESEVHLQEIKAQNTQKDFELVESGESLKKLQQQ-- 889
Cdd:pfam01576   83 RLEEE-------EERSQQLQNEKKKMQQHIQ--------------DLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDil 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  890 -LEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALkvvqVQLEQLQQQAAASGEEGSKTVAKLHDEI 968
Cdd:pfam01576  142 lLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMI----SDLEERLKKEEKGRQELEKAKRKLEGES 217

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  969 SQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQ---- 1044
Cdd:pfam01576  218 TDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQrrdl 297

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1045 ---LEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQ 1121
Cdd:pfam01576  298 geeLEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK 377

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1122 EMLQKEKELQELrqqlQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAEL 1201
Cdd:pfam01576  378 AKQALESENAEL----QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAEL----AEKLSKLQSELESVSSLL 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1202 QHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELfEMEADMNSERliekvtgikeE 1281
Cdd:pfam01576  450 NEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEE-EEEAKRNVER----------Q 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1282 LKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE--------------IQQSLQELQDSVKQKEELVQN 1347
Cdd:pfam01576  519 LSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEkaaaydklektknrLQQELDDLLVDLDHQRQLVSN 598

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1348 LEEKVRESSSII---EAQNTKLNESNVQLENK-----------TSCLKETQDQLLESQKKEKQLQEE----------AAK 1403
Cdd:pfam01576  599 LEKKQKKFDQMLaeeKAISARYAEERDRAEAEareketralslARALEEALEAKEELERTNKQLRAEmedlvsskddVGK 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1404 LSGEL--------QQVQEANG---DIKDSLVKVEELVKVLEEKLQAATSQ----LDAQQATNKELQELLVKS-------Q 1461
Cdd:pfam01576  679 NVHELerskraleQQVEEMKTqleELEDELQATEDAKLRLEVNMQALKAQferdLQARDEQGEEKRRQLVKQvreleaeL 758

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1462 ENEGNLQGESLAVTEKLQ--------QLEQANGELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQK 1533
Cdd:pfam01576  759 EDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQ----LKKLQAQMKDLQRELEEARASRDEILAQSKESEKK 834

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1534 ERTLQEETSKLAEQLSQLKQAN-----------EELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-------MDDAASV 1595
Cdd:pfam01576  835 LKNLEAELLQLQEDLAASERARrqaqqerdelaDEIASGASGKSALQDEKRRLEARIAQLEEELEEeqsntelLNDRLRK 914

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|....
gi 1834199290 1596 KSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1639
Cdd:pfam01576  915 STLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEME 958
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 731-1550 5.63e-15

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 80.93  E-value: 5.63e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  731 MRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELvqskeQAAKTLNdkeqlEKQISDLK 810
Cdd:pfam15921  100 LHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL-----EAAKCLK-----EDMLEDSN 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  811 QLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNEledfqkKQSESEVHLQEIKAQNTQKDFELVESGESLK----KL 886
Cdd:pfam15921  170 TQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYE------HDSMSTMHFRSLGSAISKILRELDTEISYLKgrifPV 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  887 QQQLEQ-KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLH 965
Cdd:pfam15921  244 EDQLEAlKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLE 323

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  966 DEISQLKSQAEETQselKSTQSNLEAKSKQLEAANGSLEEE-------AKKSGHLLEQITKLKSEVGETQAALSSCHTDV 1038
Cdd:pfam15921  324 STVSQLRSELREAK---RMYEDKIEELEKQLVLANSELTEArterdqfSQESGNLDDQLQKLLADLHKREKELSLEKEQN 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1039 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSdeiatghkELTSKADA 1118
Cdd:pfam15921  401 KRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS--------SLTAQLES 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1119 wSQEMLQKEKElqelrqqlqdsqdSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLElstgtqttIKDLQERLEITN 1198
Cdd:pfam15921  473 -TKEMLRKVVE-------------ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAE--------ITKLRSRVDLKL 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1199 AELQHkekmasedaqkiadLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGI 1278
Cdd:pfam15921  531 QELQH--------------LKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1279 KE------ELKETHLQLDERQKKFEELE--------EKLKQAQQSEQKLQQESQTSKEK---LTEIQQSLQELQDSVKQK 1341
Cdd:pfam15921  597 KEindrrlELQEFKILKDKKDAKIRELEarvsdlelEKVKLVNAGSERLRAVKDIKQERdqlLNEVKTSRNELNSLSEDY 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1342 EELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1421
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEA 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1422 LVKVEELVKVLEEKLQAATSQLDA-QQATNKELQEL-LVKSQEN---------EGNLQGESLAVTE---KLQQLEQANGE 1487
Cdd:pfam15921  757 MTNANKEKHFLKEEKNKLSQELSTvATEKNKMAGELeVLRSQERrlkekvanmEVALDKASLQFAEcqdIIQRQEQESVR 836

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1488 LKealCQKENGLKELQGKLDESNTVLE-------SQKKSHNEIQDK------LEQAQQKERTLQEETSKLAEQLSQ 1550
Cdd:pfam15921  837 LK---LQHTLDVKELQGPGYTSNSSMKprllqpaSFTRTHSNVPSSqstasfLSHHSRKTNALKEDPTRDLKQLLQ 909
PTZ00121 PTZ00121
MAEBL; Provisional
 769-1477 6.94e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.96  E-value: 6.94e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  769 EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTE-NAINQIQLEKESIEQQLALKQNE 847
Cdd:PTZ00121  1080 DFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKaEDARKAEEARKAEDAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  848 LEDFQK----------KQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKEtiIKE 917
Cdd:PTZ00121  1160 AEDARKaeearkaedaKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEE--AKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  918 KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKtvAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLE 997
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  998 AAngslEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 1077
Cdd:PTZ00121  1316 KA----DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1078 DTLHAELQAERSSSSALHTKLSKFSDEIAtghKELTSKADAwSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERK--- 1154
Cdd:PTZ00121  1392 KADEAKKKAEEDKKKADELKKAAAAKKKA---DEAKKKAEE-KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKkae 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1155 EKSFEESIKNLQEEVTKAKtenlELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE---AIQVANAN 1231
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKAD----EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEakkADEAKKAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1232 ISATNAELSTVLEVLQAEksETNHIFELFEMEADMN-SERLIEKVTGIKEELKETHLQLDERQKKFEelEEKLKQAQQSE 1310
Cdd:PTZ00121  1544 EKKKADELKKAEELKKAE--EKKKAEEAKKAEEDKNmALRKAEEAKKAEEARIEEVMKLYEEEKKMK--AEEAKKAEEAK 1619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1311 QKLQQESQTSKEKlTEIQQSLQELQDSVKQKEELVQNLEE---KVRESSSIIEAQNTKLNESNVQLENKtsclKETQDQL 1387
Cdd:PTZ00121  1620 IKAEELKKAEEEK-KKVEQLKKKEAEEKKKAEELKKAEEEnkiKAAEEAKKAEEDKKKAEEAKKAEEDE----KKAAEAL 1694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1388 LESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAtSQLDAQQATNKELQELLVKSQENEGNL 1467
Cdd:PTZ00121  1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA-EEAKKDEEEKKKIAHLKKEEEKKAEEI 1773

                          730
                   ....*....|
gi 1834199290 1468 QGESLAVTEK 1477
Cdd:PTZ00121  1774 RKEKEAVIEE 1783
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
959-1548 6.96e-15

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 80.49  E-value: 6.96e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  959 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghlLEQITKLKSEVGETQAALSSCHTDV 1038
Cdd:PRK03918   172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREE----LEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1039 ESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITdtlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSkada 1118
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-----ELKEKAEEYIKLSEFYEEYLDELREIEKRLSR---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1119 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEESIKNLQEevTKAKTENLE-----LSTGTQTTIKDLQER 1193
Cdd:PRK03918   319 LEEEINGIEERIKELEEKEERLEELKKKLK-ELEKRLEELEERHELYEE--AKAKKEELErlkkrLTGLTPEKLEKELEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1194 LEITNAELQHKEK----MASEDAQKIADLKTLVEAIQVANANISATNAELS-----TVLEVLQAE-KSETNHIFELFEME 1263
Cdd:PRK03918   396 LEKAKEEIEEEISkitaRIGELKKEIKELKKAIEELKKAKGKCPVCGRELTeehrkELLEEYTAElKRIEKELKEIEEKE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1264 ADMNSE-RLIEKVTGIKEEL---KETHLQLDERQKKFEELE-EKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1338
Cdd:PRK03918   476 RKLRKElRELEKVLKKESELiklKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1339 KQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1418
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1419 KDSLVKVEELVKVLEEKLQAATsqldaqQATNKELQELLVKsqenegnLQGESLAVTEKLQQLEQANGELKEALCQKENG 1498
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYS------EEEYEELREEYLE-------LSRELAGLRAELEELEKRREEIKKTLEKLKEE 702

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1499 LKELQGKLDESNtVLESQKKSHNEIQDKLE--QAQQKERTLQeETSKLAEQL 1548
Cdd:PRK03918   703 LEEREKAKKELE-KLEKALERVEELREKVKkyKALLKERALS-KVGEIASEI 752
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 974-1665 1.13e-14

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 80.01  E-value: 1.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  974 QAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLKSEVGETQAALsschtDVESKTKQLEAANAALE 1053
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQL-KKQQLLKQLRARIEELRAQEAVLEETQERI-----NRARKAAPLAAHIKAVT 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1054 KVNKEYAESRAEasdLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKEL-TSKADAWSQEMLQKEKELQE 1132
Cdd:TIGR00618  304 QIEQQAQRIHTE---LQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDaHEVATSIREISCQQHTLTQH 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1133 LRQQLQDSQDSQTKLKAEGERKEKsfeesiknLQEEVTKAKTENLELSTGTQ------TTIKDLQERLEITNA------- 1199
Cdd:TIGR00618  381 IHTLQQQKTTLTQKLQSLCKELDI--------LQREQATIDTRTSAFRDLQGqlahakKQQELQQRYAELCAAaitctaq 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1200 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSE--------TNHIFELFEMEADMNS-ER 1270
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPlcgscihpNPARQDIDNPGPLTRRmQR 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1271 LIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSvkqkeelvqnLEE 1350
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL----------TEK 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1351 KVRESSSIIEAQNTKLNESNVQLENktsclketQDQLLESQKKEKQLQEEAAKLSGELQQVqeANGDIKDSLVKVEELVK 1430
Cdd:TIGR00618  603 LSEAEDMLACEQHALLRKLQPEQDL--------QDVRLHLQQCSQELALKLTALHALQLTL--TQERVREHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:TIGR00618  673 ELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TvlESQKKSHNEIQDKLEQAQQKERTLQEetsklaeqLSQLKQANEELQKSLQQKQLLLEkgnefdTQLAEYQKVIDEMD 1590
Cdd:TIGR00618  753 R--TVLKARTEAHFNNNEEVTAALQTGAE--------LSHLAAEIQFFNRLREEDTHLLK------TLEAEIGQEIPSDE 816

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1591 DAASVKSALL----EQLQNRVAELETALRQAndaqKTAYLETKELRRQLESLeLEKSREVLSLKAQMNGASSRSGKGDE 1665
Cdd:TIGR00618  817 DILNLQCETLvqeeEQFLSRLEEKSATLGEI----THQLLKYEECSKQLAQL-TQEQAKIIQLSDKLNGINQIKIQFDG 890
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1188-1650 3.13e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 78.57  E-value: 3.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1188 KDLQERLEITNAELQHKEK--MASEDAQ-KIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEmEA 1264
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKfiKRTENIEeLIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE-EL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1265 DMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKlQQESQTSKEKLTEIQQSLQELQDSVKQKEEL 1344
Cdd:PRK03918   244 EKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK-AEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1345 VQNLEEKVRESSSIiEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG--------ELQQVQEANG 1416
Cdd:PRK03918   323 INGIEERIKELEEK-EERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGltpeklekELEELEKAKE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1417 DIKDSLVKVEELVKVLEEK---LQAATSQLDAQQAT----NKELQEllvksqENEGNLQGEslaVTEKLQQLEQANGELK 1489
Cdd:PRK03918   402 EIEEEISKITARIGELKKEikeLKKAIEELKKAKGKcpvcGRELTE------EHRKELLEE---YTAELKRIEKELKEIE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1490 EALCQKENGLKELQGKLDESNTV------------LESQKKSHNeiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1557
Cdd:PRK03918   473 EKERKLRKELRELEKVLKKESELiklkelaeqlkeLEEKLKKYN--LEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1558 LQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksalLEQLQNRVAELETALRQANDAQKTAY-LETKELRRQLE 1636
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAELLKELEELGFES------VEELEERLKELEPFYNEYLELKDAEKeLEREEKELKKL 624

                          490
                   ....*....|....
gi 1834199290 1637 SLELEKSREVLSLK 1650
Cdd:PRK03918   625 EEELDKAFEELAET 638
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
760-1354 3.21e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 78.57  E-value: 3.21e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  760 LDDMLRLQKEGTEEKSTLLEKTE------KELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLE 833
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTEnieeliKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  834 KESIEQQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELkkek 911
Cdd:PRK03918   247 LESLEGSKRKLEEKIRELEERIEELKKEIEELeeKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE---- 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  912 etiIKEKEQELQQLQSKSAESESALKVVQVQLEQLqqqaaasgeEGSKTVAKLHDEISQLKSQAEETQSELKS-TQSNLE 990
Cdd:PRK03918   323 ---INGIEERIKELEEKEERLEELKKKLKELEKRL---------EELEERHELYEEAKAKKEELERLKKRLTGlTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  991 AKSKQLEAANGSLEEEAKKsghLLEQITKLKSEVGETQAALSS-------CHT-----DVESKTKQLEAANAALEKVNKE 1058
Cdd:PRK03918   391 KELEELEKAKEEIEEEISK---ITARIGELKKEIKELKKAIEElkkakgkCPVcgrelTEEHRKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1059 YAESRAEASDLQDKVKEITDTLHAELQAerssssalhTKLSKFSDEIatghKELTSKADAWSQEML-QKEKELQELRQQL 1137
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESEL---------IKLKELAEQL----KELEEKLKKYNLEELeKKAEEYEKLKEKL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1138 QDSQDSQTKLKAEGERKE------KSFEESIKNLQEEVTKAKTENLELSTGtqtTIKDLQERLEitNAELQHKEKMASED 1211
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEelkkklAELEKKLDELEEELAELLKELEELGFE---SVEELEERLK--ELEPFYNEYLELKD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1212 AQKiaDLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFemeadmnSERLIEKVTGIKEELKETHLQLDE 1291
Cdd:PRK03918   610 AEK--ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-------SEEEYEELREEYLELSRELAGLRA 680

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1292 RqkkFEELEEKLKQAQQSEQKLqqesqtsKEKLTEIQQSLQELQDSVKQKEElVQNLEEKVRE 1354
Cdd:PRK03918   681 E---LEELEKRREEIKKTLEKL-------KEELEEREKAKKELEKLEKALER-VEELREKVKK 732
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
759-1349 6.17e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.39  E-value: 6.17e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  759 ALDDMLRLQKEGTEE-KSTLLEKTEKELVqskeqaaKTLNDKEQLEKQI-SDLKQLAEQEKLVREMTENAINQIQLEKES 836
Cdd:PRK02224   177 GVERVLSDQRGSLDQlKAQIEEKEEKDLH-------ERLNGLESELAELdEEIERYEEQREQARETRDEADEVLEEHEER 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  837 IEQQLALKQnELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIK 916
Cdd:PRK02224   250 REELETLEA-EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  917 EKEQELQQLQSKSAESESALKVVQVQleqlqqqaaasgEEGSKtvaKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQL 996
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADDL------------EERAE---ELREEAAELESELEEAREAVEDRREEIEELEEEI 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  997 EAANGS-------LEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDL 1069
Cdd:PRK02224   394 EELRERfgdapvdLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEED 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1070 QDKVKEITDTLhAELQAERSSSSALHTKLSKFSdEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKA 1149
Cdd:PRK02224   474 RERVEELEAEL-EDLEEEVEEVEERLERAEDLV-EAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEA 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1150 EGERKEKSFEESIKNLQEevtkaktenlelstgTQTTIKDLQERLEITNAELQHKEKMASEDAqKIADLKTLVEAIQVAN 1229
Cdd:PRK02224   552 EAEEKREAAAEAEEEAEE---------------AREEVAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLREKR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1230 ANISATNAELSTVLevlqAEKSETNHifelfEMEADMNSERLiekvtgikEELKETHLQLDERQkkfEELEEKLKQAQQS 1309
Cdd:PRK02224   616 EALAELNDERRERL----AEKRERKR-----ELEAEFDEARI--------EEAREDKERAEEYL---EQVEEKLDELREE 675

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1834199290 1310 EQKLQQESQTSKEKLTEiqqsLQELQDSVKQKEELVQNLE 1349
Cdd:PRK02224   676 RDDLQAEIGAVENELEE----LEELRERREALENRVEALE 711
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 873-1704 1.16e-13

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 76.93  E-value: 1.16e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  873 DFELVESGESLKKLQ--QQLEQKTLGHEKLQAALEELKKEKETIIKE--KEQELQQLQSKSAESESALKVVQVQLEQLQQ 948
Cdd:pfam02463  159 EEEAAGSRLKRKKKEalKKLIEETENLAELIIDLEELKLQELKLKEQakKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  949 QAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSG---------HLLEQITK 1019
Cdd:pfam02463  239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllklerrkvDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1020 LKSEVGETQAALSSCHTDVESKTKQL---EAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHT 1096
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELkelEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1097 KLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEN 1176
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1177 LELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTL------------VEAIQVANANISATNAELSTVLE 1244
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRiisahgrlgdlgVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1245 VLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS------EQKLQQESQ 1318
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKvvegilKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1319 TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQ 1398
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1399 EEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLD--AQQATNKELQELLVKSQENEGNLQGESLAVTE 1476
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEekSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1477 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAE-QLSQLKQAN 1555
Cdd:pfam02463  799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELlQELLLKEEE 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1556 EELQKSLQQKQLLLEKGNEfdtqlaeyqkvIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQL 1635
Cdd:pfam02463  879 LEEQKLKDELESKEEKEKE-----------EKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1636 ESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLET 1704
Cdd:pfam02463  948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 551-1406 1.69e-13

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 76.16  E-value: 1.69e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  551 QSQVYKEKIHDLESKITKLVSATPSLQSIL--PPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVK 628
Cdd:pfam02463  231 YLKLNEERIDLLQELLRDEQEEIESSKQEIekEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  629 YLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEftrklaeksvevLRLSSELQNLKATS 708
Cdd:pfam02463  311 DDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKL------------QEKLEQLEEELLAK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  709 DSLESERVNKTDECEILQTEVRMRDEQIRELNQQLdevttqLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQS 788
Cdd:pfam02463  379 KKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL------ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEE 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  789 KEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTEnainQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQ 868
Cdd:pfam02463  453 LEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL----LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  869 NTQKDFELVESGESLKKLQQQLEQKT------LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES-------ESA 935
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSatadevEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlAQL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  936 LKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLE 1015
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1016 QITKLKSEVGETQAALSScHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTlhaELQAERSSSSALH 1095
Cdd:pfam02463  689 LAKEEILRRQLEIKKKEQ-REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEE---EEKSRLKKEEKEE 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1096 TKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTE 1175
Cdd:pfam02463  765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEE------ELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1176 NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNH 1255
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENE 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1256 IFElfemeaDMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQ 1335
Cdd:pfam02463  919 IEE------RIKEEAEIL----LKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEE 988

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1336 DSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG 1406
Cdd:pfam02463  989 RYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELRLEDPDDPFSG 1059
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 911-1641 3.39e-13

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 75.21  E-value: 3.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  911 KETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQqqaaasgEEGSKTVAKLHDEiSQLKSQAEETQSELKSTQSNLE 990
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLC-------EEKNALQEQLQAE-TELCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  991 AKSKQLEAangSLEEEAKKSGHLL-------EQITKLKSEVGETQAALSSCHTD---VESKTKQLEAANAALEKVNKEYA 1060
Cdd:pfam01576   75 EILHELES---RLEEEEERSQQLQnekkkmqQHIQDLEEQLDEEEAARQKLQLEkvtTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1061 EsraEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADawsQEMLQK--EKELQELRQQLQ 1138
Cdd:pfam01576  152 K---ERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQE---LEKAKRklEGESTDLQEQIA 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1139 DSQDSQTKLKAEGERKEKSFEESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADL 1218
Cdd:pfam01576  226 ELQAQIAELRAQLAKKEEELQAALARLEEE-TAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEAL 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1219 KTLVEAIQvanaNISATNAELSTVLEvlqaekSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLdERQKKFEE 1298
Cdd:pfam01576  305 KTELEDTL----DTTAAQQELRSKRE------QEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQL-EQAKRNKA 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1299 LEEKLKQAQQSEQK--------LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESN 1370
Cdd:pfam01576  374 NLEKAKQALESENAelqaelrtLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1371 VQLENKTSCLKETQDQLLESQKkekQLQEEAA---KLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQ 1447
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQE---LLQEETRqklNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMK 530

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1448 ATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELkealcqkENGLKELQGKLDESNTVLESQKkshnEIQDKL 1527
Cdd:pfam01576  531 KKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL-------EKTKNRLQQELDDLLVDLDHQR----QLVSNL 599

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1528 EQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKgnefdtQLAEYQKVIDEMDDAASVKSALLEQLQNRV 1607
Cdd:pfam01576  600 EKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLAR------ALEEALEAKEELERTNKQLRAEMEDLVSSK 673

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1834199290 1608 AELETALRQANDAQKTAYLETKELRRQLESLELE 1641
Cdd:pfam01576  674 DDVGKNVHELERSKRALEQQVEEMKTQLEELEDE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 513-1085 4.17e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 4.17e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  513 LKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITklvsatpslqsilppdlpsddgALQ 592
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----------------------EAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEkfslsecgienlrrelelLKEEN 672
Cdd:COG1196    288 AEEYELLA----ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE------------------ELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  673 EKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNV 752
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  753 QKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQL 832
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  833 EKESIEQQLALKQN-----ELEDFQKKQSESEVHLQEIKAQNTQKDfeLVESGESLKKLQQQLEQKTLG----------- 896
Cdd:COG1196    506 FLEGVKAALLLAGLrglagAVAVLIGVEAAYEAALEAALAAALQNI--VVEDDEVAAAAIEYLKAAKAGratflpldkir 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  897 -HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQA 975
Cdd:COG1196    584 aRAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  976 EETQSELkstQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKV 1055
Cdd:COG1196    664 GGSRREL---LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                          570       580       590
                   ....*....|....*....|....*....|
gi 1834199290 1056 NKEYAESRAEASDLQDKVKEITDTLHAELQ 1085
Cdd:COG1196    741 LLEEEELLEEEALEELPEPPDLEELERELE 770
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1121-1685 5.15e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 74.33  E-value: 5.15e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1121 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEEsIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAE 1200
Cdd:PRK03918   200 KELEEVLREINEISSELPELREELEKLEKEVKELEELKEE-IEELEKELESLEGSKRKL----EEKIRELEERIEELKKE 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1201 LQHKEKMASE------DAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmNSERLIEK 1274
Cdd:PRK03918   275 IEELEEKVKElkelkeKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE------------EKEERLEE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1275 VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskekLTEIQQSLQELQDSVKQKEELVQNLEEKVRE 1354
Cdd:PRK03918   343 LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT------PEKLEKELEELEKAKEEIEEEISKITARIGE 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1355 SSSIIEAQNTKLNESNVQ-------------------LENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAN 1415
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1416 gdikdSLVKVEELVKVLEEKLQAAtsQLDAQQATNKELQELLVKSQENEGNLQGESLAVtEKLQQLEQANGELKEALCQK 1495
Cdd:PRK03918   497 -----KLKELAEQLKELEEKLKKY--NLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL-EKLEELKKKLAELEKKLDEL 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1496 ENGLKELQGKLDE----SNTVLESQ--------------KKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEE 1557
Cdd:PRK03918   569 EEELAELLKELEElgfeSVEELEERlkelepfyneylelKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1558 LQkslqqkqlllEKGNEFDTQlaEYQKVIDEMddaasvksallEQLQNRVAELETALRQANDAQKTAYLETKELRRQLES 1637
Cdd:PRK03918   649 LE----------ELEKKYSEE--EYEELREEY-----------LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1834199290 1638 LElEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSII 1685
Cdd:PRK03918   706 RE-KAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 834-1566 9.80e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 73.61  E-value: 9.80e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  834 KESIEQQLALKQNELEDFQKKQSES-EVH-----------------LQEIKAQ-NTQKDFELVESgESLKKLQQQLEQKT 894
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESnELHekqkfylrqsvidlqtkLQEMQMErDAMADIRRRES-QSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  895 LGHEKLQAALEELKKEKETIIKE-------KEQELQQLQSKSAESESAL-KVVQVQLEQLQQQAAASGEEGSKTVAKLHD 966
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQlrkmmlsHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAISKILRELDT 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  967 EISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkKSGHLLEqITKLKSEVGETQAALSSCHTDVESKTKQLE 1046
Cdd:pfam15921  232 EISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-ISEHEVE-ITGLTEKASSARSQANSIQSQLEIIQEQAR 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1047 AANAAL--------EKVNKEYAESRAEASDLQDKVKEITDTL---HAELQAERS-------SSSALHTKLSKFSDEIATG 1108
Cdd:pfam15921  310 NQNSMYmrqlsdleSTVSQLRSELREAKRMYEDKIEELEKQLvlaNSELTEARTerdqfsqESGNLDDQLQKLLADLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1109 HKELTSKADA----WSQEM---LQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQeevtkAKTENLELST 1181
Cdd:pfam15921  390 EKELSLEKEQnkrlWDRDTgnsITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ-----GKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1182 GTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE----AIQVANANISATNAELSTVLEVLQAEKSETNHIf 1257
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQekerAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL- 543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1258 elfemeadmnserliekvTGIKEELKETHLQLDERQKKFEELEEKLKQAQQ-------SEQKLQQESQTSKEKLTEIQQS 1330
Cdd:pfam15921  544 ------------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrTAGAMQVEKAQLEKEINDRRLE 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1331 LQELQDSVKQKEELVQNLEEKVressSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeEAAKLSGELQQ 1410
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRN---ELNSLSEDYEV 678

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1411 VQEangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-------ELLVKSQENEGNLQGESLAVTEKLQQLEQ 1483
Cdd:pfam15921  679 LKR---NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdghamKVAMGMQKQITAKRGQIDALQSKIQFLEE 755

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1484 ANGELKealcQKENGLKELQGKLDESNTVLESQKkshNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQ 1563
Cdd:pfam15921  756 AMTNAN----KEKHFLKEEKNKLSQELSTVATEK---NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828


                   ...
gi 1834199290 1564 QKQ 1566
Cdd:pfam15921  829 RQE 831
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 728-1090 1.08e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 1.08e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  728 EVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAaktlndkEQLEKQIS 807
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERL-------EELEEDLS 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  808 DLKQlaEQEKLVREMTENAinqiqLEKESIEQQLALKQNELEDFQKKQSESEVhlQEIKAQNTQKDFELVESGESLKKLQ 887
Cdd:TIGR02169  748 SLEQ--EIENVKSELKELE-----ARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAELSKLEEEVSRIEARLREIE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  888 QQLEQKTLGHEKLQAALEELKKEKETI---IKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKL 964
Cdd:TIGR02169  819 QKLNRLTLEKEYLEKEIQELQEQRIDLkeqIKSIEKEIENLNGKKEELEEEL------------------EELEAALRDL 880

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  965 HDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHT--DVESKT 1042
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSleDVQAEL 960

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1043 KQLEAANAALEKVN----KEYAESRAEASDLQDKvkeitdtlHAELQAERSS 1090
Cdd:TIGR02169  961 QRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEK--------RAKLEEERKA 1004
PRK11281 PRK11281
mechanosensitive channel MscK;
1278-1654 1.12e-12

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 73.41  E-value: 1.12e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQesqtskeklteIQQSLQELQDSvkQKEELVQNLeekvrESSS 1357
Cdd:PRK11281    61 VQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQ-----------AQAELEALKDD--NDEETRETL-----STLS 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1358 IIEAQNtKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQeeaAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQ 1437
Cdd:PRK11281   123 LRQLES-RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQ---AALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQ 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1438 AATSQLDAQQ-------ATNKELQELLvKSQENEgnlqgeslaVTEKLQQLEQANGELKEALCQKEngLKELQGKLDESN 1510
Cdd:PRK11281   199 AEQALLNAQNdlqrkslEGNTQLQDLL-QKQRDY---------LTARIQRLEHQLQLLQEAINSKR--LTLSEKTVQEAQ 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TVLESQKKSHNE-IQDKLEQAQQKERTLQEETSKLAE----------QLSQLKQAN---EE----LQKSL-------QQK 1565
Cdd:PRK11281   267 SQDEAARIQANPlVAQELEINLQLSQRLLKATEKLNTltqqnlrvknWLDRLTQSErniKEqisvLKGSLllsrilyQQQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1566 QLL--LEKGNEFDTQLAE---YQKVIDEMDDAasvksalLEQLQNRVAELEtalrqANDAQKtaylETKELRRQLESLeL 1640
Cdd:PRK11281   347 QALpsADLIEGLADRIADlrlEQFEINQQRDA-------LFQPDAYIDKLE-----AGHKSE----VTDEVRDALLQL-L 409

                          410
                   ....*....|....*....
gi 1834199290 1641 EKSREVL-----SLKAQMN 1654
Cdd:PRK11281   410 DERRELLdqlnkQLNNQLN 428
mukB PRK04863
chromosome partition protein MukB;
1270-1644 2.02e-12

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 72.68  E-value: 2.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1270 RLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkqkeelvQNLE 1349
Cdd:PRK04863   283 VHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQ------------QEKI 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1350 EKVRESssiieaqntkLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAngdikdslvkveelv 1429
Cdd:PRK04863   351 ERYQAD----------LEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQA--------------- 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1430 kvleeklqaatsqLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKL 1506
Cdd:PRK04863   406 -------------LDVQQTRAIQYQQAVQALERAKQLCGLPDLTADnaeDWLEEFQAKEQEATEELLSLEQKLSVAQAAH 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1507 DESNTVLESQKKSHNEI--QDKLEQAQQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnefdtQLAEYQK 1584
Cdd:PRK04863   473 SQFEQAYQLVRKIAGEVsrSEAWDVARELLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQQRAER-------LLAEFCK 544

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1585 VIDEMDDAAsvksALLEQLQnrvAELETALRQANDAQKTAYLETKELRRQLESLELEKSR 1644
Cdd:PRK04863   545 RLGKNLDDE----DELEQLQ---EELEARLESLSESVSEARERRMALRQQLEQLQARIQR 597
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
604-1175 2.13e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 72.40  E-value: 2.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  604 IQQKEVESRIAEQLEEEQRLRENV---KYLN--EQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQe 678
Cdd:PRK03918   132 IRQGEIDAILESDESREKVVRQILgldDYENayKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREIN- 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  679 aqaEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVnktdECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSS 758
Cdd:PRK03918   211 ---EISSELPELREELEKLEKEVKELEELKEEIEELEK----ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK 283

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  759 ALDDmLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE 838
Cdd:PRK03918   284 ELKE-LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  839 --QQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVEsgESLKKLQQQLEQKTLGHEKLQAALEELKK------- 909
Cdd:PRK03918   363 lyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIE--EEISKITARIGELKKEIKELKKAIEELKKakgkcpv 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  910 --------EKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAaasgeEGSKTVAKLHDEISQLKSQAEETQS- 980
Cdd:PRK03918   441 cgrelteeHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKy 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  981 -----ELKSTQ-SNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESK----TKQLEAANA 1050
Cdd:PRK03918   516 nleelEKKAEEyEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1051 ALEKVNKEYAESRAEASDLQDKVKEITDT----------LHAELQAERSSSSALHTKLSKFSDEiatGHKELTSKADAWS 1120
Cdd:PRK03918   596 ELEPFYNEYLELKDAEKELEREEKELKKLeeeldkafeeLAETEKRLEELRKELEELEKKYSEE---EYEELREEYLELS 672

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1121 QEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEES---------IKNLQEEVTKAKTE 1175
Cdd:PRK03918   673 RELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELeklekalerVEELREKVKKYKAL 736
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1237-1698 2.27e-12

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 72.38  E-value: 2.27e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1237 AELSTVLEVLQAEKSETNHIFELFEMEADMNSERLiEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE 1316
Cdd:PRK02224   202 KDLHERLNGLESELAELDEEIERYEEQREQARETR-DEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1317 SQTSKEKLTEIQQSLQEL----------QDSVKQKEELVQNLEEKVRESssiIEAQNTKLNESNVQLENktscLKETQDQ 1386
Cdd:PRK02224   281 VRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDR---LEECRVAAQAHNEEAES----LREDADD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1387 LlESQKKEkqLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQEllvksqenegn 1466
Cdd:PRK02224   354 L-EERAEE--LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELRE----------- 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1467 lqgESLAVTEKLQQLEqanGELKEAlcqkENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAE 1546
Cdd:PRK02224   420 ---ERDELREREAELE---ATLRTA----RERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEE 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1547 QLSQLKQ---ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKT 1623
Cdd:PRK02224   490 EVEEVEErleRAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERA-------EELRERAAELEAEAEEKREAAAE 562

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1624 AYLETKELRRQLESLEleksrevlslkaqmngaSSRSGKGDEVESLD-IETSLAKINFLNSIIADMQQKNDALKAK 1698
Cdd:PRK02224   563 AEEEAEEAREEVAELN-----------------SKLAELKERIESLErIRTLLAAIADAEDEIERLREKREALAEL 621
PTZ00121 PTZ00121
MAEBL; Provisional
 1043-1661 2.78e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.48  E-value: 2.78e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1043 KQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIAT--GHKELTSKAD-AW 1119
Cdd:PTZ00121  1200 RKAEAARKA-EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAhfARRQAAIKAEeAR 1278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1120 SQEMLQKEKELQ---ELRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQER 1193
Cdd:PTZ00121  1279 KADELKKAEEKKkadEAKKAEEKKKADEAKKKAEEAKKAdeaKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1194 LEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAE---------KSETNHIFELFEMEA 1264
Cdd:PTZ00121  1359 AEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakkkadeaKKKAEEKKKADEAKK 1438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1265 DMNSERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEKLKQAQQSEQkLQQESQTSKEKLTEIQQSLQELQ--DSVKQ 1340
Cdd:PTZ00121  1439 KAEEAKKADEAKKKAEEAKkaEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKKAEEAKKKADEAKKAAEAKKkaDEAKK 1517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1341 KEELVQNLE-EKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIK 1419
Cdd:PTZ00121  1518 AEEAKKADEaKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1420 DSLVKVEELVKVlEEKLQAATSQLDAQQATNKELQEllvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEngl 1499
Cdd:PTZ00121  1598 MKLYEEEKKMKA-EEAKKAEEAKIKAEELKKAEEEK---KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA--- 1670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1500 KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE--RTLQEETSKLAEQL-----------SQLKQANEELQKSLQQKQ 1566
Cdd:PTZ00121  1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKEAEEKKKAEELkkaeeenkikaEEAKKEAEEDKKKAEEAK 1750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1567 LLLEKGNEFDTQLAEYQKVIDEM--DDAASVKSALLEQLQNRVAELETALRQA------------------NDAQKTAYL 1626
Cdd:PTZ00121  1751 KDEEEKKKIAHLKKEEEKKAEEIrkEKEAVIEEELDEEDEKRRMEVDKKIKDIfdnfaniieggkegnlviNDSKEMEDS 1830

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1834199290 1627 ETKELRRQlESLELEKSREVLSLKAQMNGASSRSG 1661
Cdd:PTZ00121  1831 AIKEVADS-KNMQLEEADAFEKHKFNKNNENGEDG 1864
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 553-1026 3.24e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.59  E-value: 3.24e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  553 QVYKEKIHDLESKITKLVSATPSLQSILPpDLPSDDGALQEEIAKLQEKMtIQQKEVESRIAEQLEEEQRLRENVKYLNE 632
Cdd:TIGR04523  207 KKKIQKNKSLESQISELKKQNNQLKDNIE-KKQQEINEKTTEISNTQTQL-NQLKDEQNKIKKQLSEKQKELEQNNKKIK 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  633 QIATLQSELVSKDEALEKfsLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLE 712
Cdd:TIGR04523  285 ELEKQLNQLKSEISDLNN--QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  713 SERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQA 792
Cdd:TIGR04523  363 RELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEI 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  793 AKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTqk 872
Cdd:TIGR04523  443 KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS-- 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  873 dfELVESGESLKKLQQQLEQKTLGHE-KLQAALEELKKEK-ETIIKEKEQELQQL---QSKSAESESALKVVQVQLEQLQ 947
Cdd:TIGR04523  521 --SLKEKIEKLESEKKEKESKISDLEdELNKDDFELKKENlEKEIDEKNKEIEELkqtQKSLKKKQEEKQELIDQKEKEK 598

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290  948 QQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGE 1026
Cdd:TIGR04523  599 KDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 964-1588 4.15e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.20  E-value: 4.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  964 LHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTK 1043
Cdd:TIGR04523   73 SNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1044 QLEAANAALEKVNKEYAESRAE----ASDLQDKVKEITDTLHAELQAERSSSS-----ALHTKLSKFSDEIATGHKELTS 1114
Cdd:TIGR04523  153 ELEKLNNKYNDLKKQKEELENElnllEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiQKNKSLESQISELKKQNNQLKD 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1115 KADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEES---IKNLQEEVTKAKTENLEL-STGTQTTIKDL 1190
Cdd:TIGR04523  233 NIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNnkkIKELEKQLNQLKSEISDLnNQKEQDWNKEL 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1191 QERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEvlqaeksETNHIFELFEMEADMNSER 1270
Cdd:TIGR04523  313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1271 lIEKVTGIKEELKethLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEe 1350
Cdd:TIGR04523  386 -IKNLESQINDLE---SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLD- 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1351 kvressSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSgelQQVQEANGDIKDSLVKVEELVK 1430
Cdd:TIGR04523  461 ------NTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELE---EKVKDLTKKISSLKEKIEKLES 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKlqaatsqldAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:TIGR04523  532 EKKEK---------ESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1511 tvlesqkkshNEIQDKLEQAQQKERtlqeetsklaeqlsQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1588
Cdd:TIGR04523  603 ----------KEIEEKEKKISSLEK--------------ELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 825-1562 5.59e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 70.82  E-value: 5.59e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  825 NAINQIQLEKESIEQQLALKQNELEDFQKKqsesevhlqeikaqntqkdfelvesgesLKKLQQQLEQKtlgheklqaal 904
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKE----------------------------LKNLDKNLNKD----------- 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  905 EELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSktvaKLHDEISQLKSQAEETQSELKS 984
Cdd:TIGR04523   67 EEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN----KLEVELNKLEKQKKENKKNIDK 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  985 TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALsschTDVESKTKQLEAANAALEKVNKEYAESRA 1064
Cdd:TIGR04523  143 FLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI----DKIKNKLLKLELLLSNLKKKIQKNKSLES 218

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1065 EASDLQDKVKEITDTlhaeLQAERSSSSALHTKLSKFSDEIatghKELTSKADAWSQEMLQKEKELQelrqqlqdsqdsq 1144
Cdd:TIGR04523  219 QISELKKQNNQLKDN----IEKKQQEINEKTTEISNTQTQL----NQLKDEQNKIKKQLSEKQKELE------------- 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1145 tklkaEGERKEKSFEESIKNLQEEVTKAKTE-NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVE 1223
Cdd:TIGR04523  278 -----QNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELT 352

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1224 AIQVANANISATNAELSTVLEVLQAEKSETNhifelfemeadmnserliEKVTGIKEELKETHLQLDERQKKFEELEEKL 1303
Cdd:TIGR04523  353 NSESENSEKQRELEEKQNEIEKLKKENQSYK------------------QEIKNLESQINDLESKIQNQEKLNQQKDEQI 414

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1304 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEekvressSIIEAQNTKLNESNVQLENKTSCLKET 1383
Cdd:TIGR04523  415 KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLD-------NTRESLETQLKVLSRSINKIKQNLEQK 487

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1384 QDQLLESQKKEKQLQEEAAKLSgelQQVQEANGDIKDSLVKVEELVKVLEEKlqaatsqldAQQATNKELQELLVKSQEN 1463
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKELE---EKVKDLTKKISSLKEKIEKLESEKKEK---------ESKISDLEDELNKDDFELK 555

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1464 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1543
Cdd:TIGR04523  556 KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635

                          730
                   ....*....|....*....
gi 1834199290 1544 LAEQLSQLKQANEELQKSL 1562
Cdd:TIGR04523  636 IKSKKNKLKQEVKQIKETI 654
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1361-1621 6.00e-12

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 69.41  E-value: 6.00e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1361 AQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1440
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1441 SQLDAQQatnKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEalcqkenglkelqgkldesntVLESQKKSH 1520
Cdd:COG4942     97 AELEAQK---EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKY---------------------LAPARREQA 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1521 NEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVIDEMDDAASVKSALL 1600
Cdd:COG4942    153 EELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELAELQQEAEELEALI 229

                          250       260
                   ....*....|....*....|.
gi 1834199290 1601 EQLQNRVAELETALRQANDAQ 1621
Cdd:COG4942    230 ARLEAEAAAAAERTPAAGFAA 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1432-1659 9.26e-12

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 70.05  E-value: 9.26e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1432 LEEKLQAATSQLDAQQAtnkELQELlvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1511
Cdd:COG3206    180 LEEQLPELRKELEEAEA---ALEEF--RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPD 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1512 VLESQKKShNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgnefdtqlAEYQKVIDEMDD 1591
Cdd:COG3206    255 ALPELLQS-PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ-------------QEAQRILASLEA 320

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1592 AASVKSALLEQLQNRVAELETALRQANDAQKtaylETKELRRQLESLE-----LEKSREVLSLKAQMNGASSR 1659
Cdd:COG3206    321 ELEALQAREASLQAQLAQLEARLAELPELEA----ELRRLEREVEVARelyesLLQRLEEARLAEALTVGNVR 389
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1384-1624 1.24e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 68.64  E-value: 1.24e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1384 QDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLdaqQATNKELQELLVKSQEN 1463
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL---AALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1464 EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK 1543
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1544 LAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVIDEMDDAAsvksallEQLQNRVAELETALRQANDAQKT 1623
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELAELQQEA-------EELEALIARLEAEAAAAAERTPA 245


                   .
gi 1834199290 1624 A 1624
Cdd:COG4942    246 A 246
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
593-1075 1.73e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.32  E-value: 1.73e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSEcgIENLRRELELLKEEN 672
Cdd:PRK03918   182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELE--KELESLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  673 EKQAQEAQAEFTRK--------------LAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQ---TEVRMRDEQ 735
Cdd:PRK03918   260 KIRELEERIEELKKeieeleekvkelkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEeriKELEEKEER 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  736 IRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTL----LEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQ 811
Cdd:PRK03918   340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLtgltPEKLEKELEELEKAKEEIEEEISKITARIGELKK 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  812 LAEQEKLV---------------REMTE----NAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQK 872
Cdd:PRK03918   420 EIKELKKAieelkkakgkcpvcgRELTEehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLK 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  873 DF--ELVESGESLKKLQ-QQLEQKTLGHEKLQAALEELKKEKETIIKEKEqELQQLQSKSAESESALKVVQVQLEQLQQQ 949
Cdd:PRK03918   500 ELaeQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELE-KLEELKKKLAELEKKLDELEEELAELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  950 AaasGEEGSKTVAKLHDEISQLKSQAEEtQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQA 1029
Cdd:PRK03918   579 L---EELGFESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK 654

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290 1030 ALS-SCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKE 1075
Cdd:PRK03918   655 KYSeEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1288-1563 2.22e-11

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 68.90  E-value: 2.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1288 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEK--LTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTK 1365
Cdd:pfam05667  215 ELAAAQEWEEEWNSQGLASRLTPEEYRKRKRTKLLKriAEQLRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTDTGL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1366 LNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDA 1445
Cdd:pfam05667  295 TKGSRFTHTEKLQFTNEAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEE 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1446 QQATNKELQE----------LLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ-GKLDESNTVLE 1514
Cdd:pfam05667  375 LKEQNEELEKqykvkkktldLLPDAEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKsNKEDESQRKLE 454

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1515 SQKKSHNEIQDKLEQAQQKE---RTLQEE-------------TSKLAEQLSQLKQANEELQKSLQ 1563
Cdd:pfam05667  455 EIKELREKIKEVAEEAKQKEelyKQLVAEyerlpkdvsrsayTRRILEIVKNIKKQKEEITKILS 519
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1314-1554 2.45e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 67.48  E-value: 2.45e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1314 QQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1393
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1394 EKQLQEEAAKLSGELQQVQEANGDI----KDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLvksqenegnlqg 1469
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR------------ 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1470 eslavteklQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS 1549
Cdd:COG4942    167 ---------AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237


                   ....*
gi 1834199290 1550 QLKQA 1554
Cdd:COG4942    238 AAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1067-1705 2.64e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 68.91  E-value: 2.64e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1067 SDLQDKVKEITDT-LHAELQAERSSSSALHTKLSKFSDEIATGhKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSqt 1145
Cdd:PRK02224   190 DQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRET-- 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1146 klKAEGERKEKSFEESIKNLQEEVTKAKTEN------LELSTGTQTTIKDLQERLEITNAELQhkekmasedaqkiadlk 1219
Cdd:PRK02224   267 --IAETEREREELAEEVRDLRERLEELEEERddllaeAGLDDADAEAVEARREELEDRDEELR----------------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1220 tlvEAIQVANANISATNAELSTVLEvlQAEKSETNhifelfemeadmnSERLIEKVTGIKEELKETHLQLDERQKKFEEL 1299
Cdd:PRK02224   328 ---DRLEECRVAAQAHNEEAESLRE--DADDLEER-------------AEELREEAAELESELEEAREAVEDRREEIEEL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1300 EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSC 1379
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVET 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1380 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEangdikdsLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK 1459
Cdd:PRK02224   470 IEEDRERVEELEAELEDLEEEVEEVEERLERAED--------LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1460 SQENEGNLQGESLAVTEKLQQLEQANGELKEALcqkenglKELQGKLDESNTVLESQkkshNEIQDKLEQAQQKERTLQE 1539
Cdd:PRK02224   542 LRERAAELEAEAEEKREAAAEAEEEAEEAREEV-------AELNSKLAELKERIESL----ERIRTLLAAIADAEDEIER 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1540 etskLAEQLSQLKQANEELQKSLQQKqlllekgNEFDTQLAEyqkvidEMDDAAsvksalLEQLQNRVAELETALRQAND 1619
Cdd:PRK02224   611 ----LREKREALAELNDERRERLAEK-------RERKRELEA------EFDEAR------IEEAREDKERAEEYLEQVEE 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1620 aqktaylETKELRRQLESLEleksrevlslkAQMNGASSrsgkgdEVESLDietslakinflnsiiaDMQQKNDALKAKV 1699
Cdd:PRK02224   668 -------KLDELREERDDLQ-----------AEIGAVEN------ELEELE----------------ELRERREALENRV 707


                   ....*.
gi 1834199290 1700 QTLETL 1705
Cdd:PRK02224   708 EALEAL 713
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1259-1570 4.31e-11

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 67.55  E-value: 4.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1259 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSV 1338
Cdd:PRK04778    88 LFEAEELNDKFRFRK----AKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSF 163

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1339 --------KQKEELVQNLEEKVRESSS--IIEAQNT--KLNESNVQLENKT--------SCLKETQDQLLESQKKEKQLQ 1398
Cdd:PRK04778   164 gpaldeleKQLENLEEEFSQFVELTESgdYVEAREIldQLEEELAALEQIMeeipellkELQTELPDQLQELKAGYRELV 243

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1399 EE-----AAKLSGELQQVQEAngdIKDSLVKVEEL-VKVLEEKLQAATSQLD-----------AQQ---ATNKELQELLV 1458
Cdd:PRK04778   244 EEgyhldHLDIEKEIQDLKEQ---IDENLALLEELdLDEAEEKNEEIQERIDqlydilerevkARKyveKNSDTLPDFLE 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1459 KSQENEGNLQGEslavTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1538
Cdd:PRK04778   321 HAKEQNKELKEE----IDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELEEILKQLEEIE 396

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1834199290 1539 EETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1570
Cdd:PRK04778   397 KEQEKLSEMLQGLRKDELEAREKLERYRNKLH 428
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1271-1639 4.31e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 4.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1271 LIEKVTGIKE--ELKETHL-QLDERQKKFEELEEKLKQAQQSEQKLQQESQTsKEKLTEIQQSLQELQDSVKQKEElvqn 1347
Cdd:TIGR02169  158 IIDEIAGVAEfdRKKEKALeELEEVEENIERLDLIIDEKRQQLERLRREREK-AERYQALLKEKREYEGYELLKEK---- 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1348 leEKVRESSSIIEAQNTKLNESNVQLEnktsclKETQDQLLESQKKEKQLQEEAAKL----SGELQQVQEANGDIKDSLV 1423
Cdd:TIGR02169  233 --EALERQKEAIERQLASLEEELEKLT------EEISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1424 KVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQ 1503
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1504 GKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGnefDTQLAEYQ 1583
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQ---EWKLEQLA 461

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1584 KVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLE 1639
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1477-1705 5.00e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 5.00e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1477 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLS----QLK 1552
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIArleeRRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1553 QANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELR 1632
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1633 RQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1705
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 538-1129 5.39e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 5.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  538 IDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTI----QQKEVESRI 613
Cdd:pfam15921  194 VDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLI 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  614 AEQLEEEQRLRENVKYLNEQIATLQSEL-VSKDEALEKFSLSECGIENLRRELELLKEenekQAQEAQAEFTRKLAEKSV 692
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSIQSQLeIIQEQARNQNSMYMRQLSDLESTVSQLRS----ELREAKRMYEDKIEELEK 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  693 EVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQI---RELNQQL-----------DEVTTQLNVQKADSS 758
Cdd:pfam15921  350 QLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELsleKEQNKRLwdrdtgnsitiDHLRRELDDRNMEVQ 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  759 ALDDMLRLQKE----GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLK----QLAEQEKLVREMT------E 824
Cdd:pfam15921  430 RLEALLKAMKSecqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTakkmTLESSERTVSDLTaslqekE 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  825 NAINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTL---GHEKLQ 901
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDLKLQELQHLKNEGD----HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTA 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  902 AALEELKKEKETIIKEKEQELQQ---LQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEET 978
Cdd:pfam15921  586 GAMQVEKAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  979 QSELKS-------TQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI-TKLKSEVGETQAALS---SCHTDVESKTKQLEA 1047
Cdd:pfam15921  666 RNELNSlsedyevLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTrNTLKSMEGSDGHAMKvamGMQKQITAKRGQIDA 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1048 ANA-------ALEKVNKEYAESRAEASDLQDKVKEIT---DTLHAELQAERSSSSALHTKLSKFsdEIATGHKELTSkad 1117
Cdd:pfam15921  746 LQSkiqfleeAMTNANKEKHFLKEEKNKLSQELSTVAtekNKMAGELEVLRSQERRLKEKVANM--EVALDKASLQF--- 820

                          650
                   ....*....|..
gi 1834199290 1118 AWSQEMLQKEKE 1129
Cdd:pfam15921  821 AECQDIIQRQEQ 832
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 237-301 6.61e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.40  E-value: 6.61e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  237 MAVGDRVIVSSGFGsrpgILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFV 301
Cdd:COG5244      4 LSVNDRVLLGDKFG----TVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFI 64
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1280-1492 6.62e-11

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 66.33  E-value: 6.62e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1280 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1359
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1360 EAQNTKLNESNVQLEnKTSclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAA 1439
Cdd:COG4942    100 EAQKEELAELLRALY-RLG--RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1440 TSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAL 1492
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 546-912 6.72e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 6.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  546 DELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpsddgalqEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRE 625
Cdd:TIGR02168  680 EELEEKIEELEEKIAELEKALAELRKELEELEEEL------------EQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  626 NVKYLNEQIATLQSELVSKDEALEKFSLSECGIEnlrrELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLK 705
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  706 ATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADssalddmlrlqkegTEEKSTLLEKTEKEL 785
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE--------------LEALLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  786 VQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELedfqkkQSESEVHLQEI 865
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEE-------LREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEA 956

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290  866 KAQNTQKDFELVESGESLKKLQQQLEQktLGHEKLqAALEELKKEKE 912
Cdd:TIGR02168  957 EALENKIEDDEEEARRRLKRLENKIKE--LGPVNL-AAIEEYEELKE 1000
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1293-1632 8.07e-11

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 66.78  E-value: 8.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1293 QKKFEELEE-----KLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLN 1367
Cdd:PRK04778    85 EEQLFEAEElndkfRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFG 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1368 ESNVQLENKtscLKETQDQLlesqKKEKQLQEEA--AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAatsQLDA 1445
Cdd:PRK04778   165 PALDELEKQ---LENLEEEF----SQFVELTESGdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELPD---QLQE 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1446 QQATNKELQEllvksqEN----EGNLQGESLAVTEKLQQLEQ--ANGELKEAlcqkENGLKELQGKLDESNTVLESQKKS 1519
Cdd:PRK04778   235 LKAGYRELVE------EGyhldHLDIEKEIQDLKEQIDENLAllEELDLDEA----EEKNEEIQERIDQLYDILEREVKA 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1520 HNE-------IQDKLEQAQQKERTLQEETsklaEQLSQLKQANEELqkslqqkqllLEKGNEFDTQLAEYQKVIDEMDDA 1592
Cdd:PRK04778   305 RKYveknsdtLPDFLEHAKEQNKELKEEI----DRVKQSYTLNESE----------LESVRQLEKQLESLEKQYDEITER 370

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1834199290 1593 ASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELR 1632
Cdd:PRK04778   371 IAEQEIAYSELQEELEEILKQLEEIEKEQEKLSEMLQGLR 410
PTZ00121 PTZ00121
MAEBL; Provisional
 527-1129 9.46e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 9.46e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  527 ERKKTEELQCSIDEAQfCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSilPPDLPSDDGALQEEIAKLQEKMTIQQ 606
Cdd:PTZ00121  1300 EKKKADEAKKKAEEAK-KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA--EAEAAADEAEAAEEKAEAAEKKKEEA 1376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  607 KEvESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIEnlrreLELLKEENEKQAQEA-QAEFTR 685
Cdd:PTZ00121  1377 KK-KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE-----EKKKADEAKKKAEEAkKADEAK 1450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  686 KLAE--KSVEVLRLSSElQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIR---ELNQQLDEVTTQLNVQKADSSAL 760
Cdd:PTZ00121  1451 KKAEeaKKAEEAKKKAE-EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKkaaEAKKKADEAKKAEEAKKADEAKK 1529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  761 DDMLRLQKEG--TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIE 838
Cdd:PTZ00121  1530 AEEAKKADEAkkAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  839 QQLalKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQqqlEQKTLGHEKLQAALEELKKEKETIIKEK 918
Cdd:PTZ00121  1610 EEA--KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAE---EENKIKAAEEAKKAEEDKKKAEEAKKAE 1684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  919 EQELQQLQSKSAESESALKVVQVQLEQLQQQAAasGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKqleA 998
Cdd:PTZ00121  1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK--AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK---I 1759

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  999 ANGSLEEEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQD-KVKEIT 1077
Cdd:PTZ00121  1760 AHLKKEEEKKAEEIRKEKEAVIEEELDEED---EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDsAIKEVA 1836

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1078 DTlhAELQAERSSSSALHtKLSKFSDEIATGHKELTSKADAWSQEMLQKEKE 1129
Cdd:PTZ00121  1837 DS--KNMQLEEADAFEKH-KFNKNNENGEDGNKEADFNKEKDLKEDDEEEIE 1885
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 800-1700 1.10e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.07  E-value: 1.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  800 EQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEiKAQNTQKDFELVES 879
Cdd:pfam15921   81 EEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRN-QLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  880 geslkklqqqLEQKTLGHEKLQaaLEELKKeketIIKEKEQELQQLQSKSAESESAL-KVVQVQLEQLQQQAAASGEEGS 958
Cdd:pfam15921  160 ----------LKEDMLEDSNTQ--IEQLRK----MMLSHEGVLQEIRSILVDFEEASgKKIYEHDSMSTMHFRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  959 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLeaangsLEEEAKKSGHLleqITKLKSEVGETQAALSSCHTDV 1038
Cdd:pfam15921  224 KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQL---ISEHEVEITGLTEKASSARSQA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1039 ESKTKQLEAANAALEKVNKEYAEsraEASDLQDKVKEITDTLhaelqaeRSSSSALHTKLSKFSDEIATGHKELT---SK 1115
Cdd:pfam15921  295 NSIQSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSEL-------REAKRMYEDKIEELEKQLVLANSELTearTE 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1116 ADAWSQEMLQKEKELQelrqqlqdsqdsqtKLKAEGERKEKsfeesiknlqeEVTKAKTENLEL---STGTQTTIKDLQE 1192
Cdd:pfam15921  365 RDQFSQESGNLDDQLQ--------------KLLADLHKREK-----------ELSLEKEQNKRLwdrDTGNSITIDHLRR 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1193 RLEITNAELQHKEKMasedaqkiadlktlveaiqvananisatnaelstvlevLQAEKSETNHIFELfEMEADMNSERLI 1272
Cdd:pfam15921  420 ELDDRNMEVQRLEAL--------------------------------------LKAMKSECQGQMER-QMAAIQGKNESL 460

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1273 EKVTGIKEELKETHLQLderQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1352
Cdd:pfam15921  461 EKVSSLTAQLESTKEML---RKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLK 537

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1353 RESSSIIEAQnTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEangDIKDSLVKVEELvKVL 1432
Cdd:pfam15921  538 NEGDHLRNVQ-TECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEK---EINDRRLELQEF-KIL 612

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1433 EEKLQAATSQLDAqqatnkelqellvksqenegnlqgeslavteKLQQLEQANGELKEALCQKENGLKELQGKLDEsntV 1512
Cdd:pfam15921  613 KDKKDAKIRELEA-------------------------------RVSDLELEKVKLVNAGSERLRAVKDIKQERDQ---L 658

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1513 LESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDtqlAEYQKVIDEMDDA 1592
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSD---GHAMKVAMGMQKQ 735

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1593 ASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMngaSSRSGKGDEVESLDIE 1672
Cdd:pfam15921  736 ITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLR---SQERRLKEKVANMEVA 812

                          890       900
                   ....*....|....*....|....*...
gi 1834199290 1673 TSLAKINFLNSIIADMQQKNDALKAKVQ 1700
Cdd:pfam15921  813 LDKASLQFAECQDIIQRQEQESVRLKLQ 840
mukB PRK04863
chromosome partition protein MukB;
728-1639 1.62e-10

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 66.52  E-value: 1.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  728 EVRMRDEQIRELNQQLDEVTTQLNVQKadsSALDDMLRlqkegteeKSTLLEKTEKELVQSKEQAAKTLN-------DKE 800
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQ---YRLVEMAR--------ELAELNEAESDLEQDYQAASDHLNlvqtalrQQE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  801 QLEKQISDLK----QLAEQEKLV------REMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEvhlQEIKAqnt 870
Cdd:PRK04863   349 KIERYQADLEeleeRLEEQNEVVeeadeqQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQ---QAVQA--- 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  871 qkdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKetiiKEKEQELQQLQSKSAESESALKVVqvqleqlqqqa 950
Cdd:PRK04863   423 ------------LERAKQLCGLPDLTADNAEDWLEEFQAKE----QEATEELLSLEQKLSVAQAAHSQF----------- 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  951 aasgEEGSKTVAKLHDEISqlKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEeAKKSGHLLEQITKLKSEVGETQAA 1030
Cdd:PRK04863   476 ----EQAYQLVRKIAGEVS--RSEAWDVARELLRRLREQRHLAEQLQQLRMRLSE-LEQRLRQQQRAERLLAEFCKRLGK 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1031 LSSCHTDVESKTKQLEAAnaaLEKVNKEYAESRAEASDLQDKVKEItDTLHAELQAERSSSSALHTKLSKFSDEiaTGHK 1110
Cdd:PRK04863   549 NLDDEDELEQLQEELEAR---LESLSESVSEARERRMALRQQLEQL-QARIQRLAARAPAWLAAQDALARLREQ--SGEE 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1111 ELTSKA-DAWSQEMLQKEKELQELRQqlqdsqdsqtklkaEGERKEKSFEESIKNLQEEvtkaktenlelSTGTQTTIKD 1189
Cdd:PRK04863   623 FEDSQDvTEYMQQLLERERELTVERD--------------ELAARKQALDEEIERLSQP-----------GGSEDPRLNA 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1190 LQERLE-ITNAELQhkEKMASEDAQKI-ADLKTLVEAIQVAnanisatnaELSTVLEVLQAEKSETNhifELFEMEADMN 1267
Cdd:PRK04863   678 LAERFGgVLLSEIY--DDVSLEDAPYFsALYGPARHAIVVP---------DLSDAAEQLAGLEDCPE---DLYLIEGDPD 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1268 SerLIEKVTGIKEELKETHLQLDERQ---KKFEEL--------EEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQD 1336
Cdd:PRK04863   744 S--FDDSVFSVEELEKAVVVKIADRQwrySRFPEVplfgraarEKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSR 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1337 SVKQK---------EELVQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLKETQDQL--LESQKK---EKQLQEEAA 1402
Cdd:PRK04863   822 FIGSHlavafeadpEAELRQLNRRRVE----LERALADHESQEQQQRSQLEQAKEGLSALnrLLPRLNllaDETLADRVE 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1403 KLSGELQQVQEANGDIKdslvkveelvkvleeKLQAATSQLDAQQATnkeLQEllvkSQENEGNLQGESLAVTEKLQQLE 1482
Cdd:PRK04863   898 EIREQLDEAEEAKRFVQ---------------QHGNALAQLEPIVSV---LQS----DPEQFEQLKQDYQQAQQTQRDAK 955

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1483 QANGELKEaLCQKENGLK--ELQGKLDESNTVLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQK 1560
Cdd:PRK04863   956 QQAFALTE-VVQRRAHFSyeDAAEMLAKNSDLNEK-------LRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKS 1027

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1561 SLQQKQlllekgnefdTQLAEYQKVIDEMDDAASvkSALLEQLQNRVAELETALRqANDAQKTAY--------LETKELR 1632
Cdd:PRK04863  1028 SYDAKR----------QMLQELKQELQDLGVPAD--SGAEERARARRDELHARLS-ANRSRRNQLekqltfceAEMDNLT 1094


                   ....*..
gi 1834199290 1633 RQLESLE 1639
Cdd:PRK04863  1095 KKLRKLE 1101
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 1280-1616 2.32e-10

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 65.10  E-value: 2.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1280 EELKETHLQL----DERQKKFEELEEKLKQAQQSEQKLQ---QESQTSKEKLTEIQQS------LQELQDSVKQKEELVQ 1346
Cdd:pfam05622   69 EQLQEENFRLetarDDYRIKCEELEKEVLELQHRNEELTslaEEAQALKDEMDILRESsdkvkkLEATVETYKKKLEDLG 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1347 NLEEKVR--ESSSIIEAQNT--------KLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAng 1416
Cdd:pfam05622  149 DLRRQVKllEERNAEYMQRTlqleeelkKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKE-- 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1417 diKDSLVKVEELVKVLEEKLQAAtsqlDAQQATNKELQELLVKSQENEGNLQGE--SLAVTEKLQQLEQANGELKealCQ 1494
Cdd:pfam05622  227 --KERLIIERDTLRETNEELRCA----QLQQAELSQADALLSPSSDPGDNLAAEimPAEIREKLIRLQHENKMLR---LG 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1495 KEnglkelqgkldesntvlESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1574
Cdd:pfam05622  298 QE-----------------GSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSL 360

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1575 FDTQLAEYQKVIDEMDDAASVKSALLEQLQN--------RVAELETALRQ 1616
Cdd:pfam05622  361 LKQKLEEHLEKLHEAQSELQKKKEQIEELEPkqdsnlaqKIDELQEALRK 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1317-1560 2.57e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 64.40  E-value: 2.57e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1317 SQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLenktsclKETQDQLLESQKKEKQ 1396
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-------RALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1397 LQEEAAKLSGELQQVQEANGDIKDSLVKVEElvkvlEEKLQAATSQLDAQQA-TNKELQELLVKSQENEGNlqgeslAVT 1475
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGR-----QPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAE------ELR 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1476 EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1555
Cdd:COG4942    157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                   ....*
gi 1834199290 1556 EELQK 1560
Cdd:COG4942    237 AAAAE 241
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
591-1107 2.88e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.45  E-value: 2.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  591 LQEEIAKLQEKmtiqqkevesrIAEQLEEEQRLRENVKYLNEQIATLQSELvskDEALEKFSLSECGIEnlrrelelLKE 670
Cdd:PRK02224   256 LEAEIEDLRET-----------IAETEREREELAEEVRDLRERLEELEEER---DDLLAEAGLDDADAE--------AVE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  671 ENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTE-------VRMRDEQIRELNQQL 743
Cdd:PRK02224   314 ARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESEleeareaVEDRREEIEELEEEI 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  744 DEVTTQLN---VQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNdkeqlEKQISDLKQLAEQEKLVR 820
Cdd:PRK02224   394 EELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLE-----AGKCPECGQPVEGSPHVE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  821 EMTENainqiqlekesiEQQLALKQNELEDFQKKQSESEvhlqeikaqntqkdfELVESGESLKKLQQQLEQKtlghEKL 900
Cdd:PRK02224   469 TIEED------------RERVEELEAELEDLEEEVEEVE---------------ERLERAEDLVEAEDRIERL----EER 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  901 QAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAE---- 976
Cdd:PRK02224   518 REDLEELIAERRETIEEKRERAEELRERAAELEAE----AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIEsler 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  977 --ETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQaalsschtdVESKTKQLEAANAALEK 1054
Cdd:PRK02224   594 irTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR---------IEEAREDKERAEEYLEQ 664

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1055 VNKEYAESRAEASDLQDKVKEITDTLH--AELQAERSSSSALHTKLSKFSDEIAT 1107
Cdd:PRK02224   665 VEEKLDELREERDDLQAEIGAVENELEelEELRERREALENRVEALEALYDEAEE 719
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 780-1584 4.05e-10

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 65.07  E-value: 4.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  780 KTEKELVQSKEQAAKTlndkEQLEKQIsdLKQLAEQEKLVREMTENAINQIQLEKESIEQqlalKQNELEDFQKKQSESE 859
Cdd:TIGR00606  189 ETLRQVRQTQGQKVQE----HQMELKY--LKQYKEKACEIRDQITSKEAQLESSREIVKS----YENELDPLKNRLKEIE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  860 VHLQEI-KAQNTQKDFELVEsgESLKKLQQQLEQKTLG-HEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESalK 937
Cdd:TIGR00606  259 HNLSKImKLDNEIKALKSRK--KQMEKDNSELELKMEKvFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNK--E 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  938 VVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK-------QLEAANGSLEEEAKKS 1010
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQiknfhtlVIERQEDEAKTAAQLC 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1011 GHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSS 1090
Cdd:TIGR00606  415 ADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNS 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1091 SSALHTKLSKFsdeIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT 1170
Cdd:TIGR00606  495 LTETLKKEVKS---LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPN 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1171 KAKTENLELSTGTQttIKDLQERLEITNAELQHKEKMA----SEDAQKIADLKTLVEAI------QVANANISATNAELS 1240
Cdd:TIGR00606  572 KKQLEDWLHSKSKE--INQTRDRLAKLNKELASLEQNKnhinNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIE 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1241 TVLEVLQAEKSETNHIFELFEMEADMNSE--RLIEKVTGIKEELKETHLQLderQKKFEELEEKLKQAQQSEQKLQQESQ 1318
Cdd:TIGR00606  650 KSSKQRAMLAGATAVYSQFITQLTDENQSccPVCQRVFQTEAELQEFISDL---QSKLRLAPDKLKSTESELKKKEKRRD 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1319 TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET---QDQLLESQKKEK 1395
Cdd:TIGR00606  727 EMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVtimERFQMELKDVER 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1396 QLQEEAAKLSGElqqvqeangDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVT 1475
Cdd:TIGR00606  807 KIAQQAAKLQGS---------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIG 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1476 EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1555
Cdd:TIGR00606  878 TNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYM 957

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1834199290 1556 EELQKSLQQ--KQLLLEKGNEFDT---QLAEYQK 1584
Cdd:TIGR00606  958 KDIENKIQDgkDDYLKQKETELNTvnaQLEECEK 991
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1197-1698 4.11e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 64.74  E-value: 4.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1197 TNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERlIEKVT 1276
Cdd:pfam05483   97 IEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEK-TKKYE 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1277 GIKEELKETHLQLDER-QKKFEELEEKLKQAQQSEQKLQQESQTSKEKlteIQQSLQELQDSVKQKEELVQNL------- 1348
Cdd:pfam05483  176 YEREETRQVYMDLNNNiEKMILAFEELRVQAENARLEMHFKLKEDHEK---IQHLEEEYKKEINDKEKQVSLLliqitek 252

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1349 EEKVRESSSIIEAQNTKLNesnvQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1428
Cdd:pfam05483  253 ENKMKDLTFLLEESRDKAN----QLEEKT---KLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKT 325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1429 VKVLEEKLQAATSQLDAQQATNK-----------ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEN 1497
Cdd:pfam05483  326 ICQLTEEKEAQMEELNKAKAAHSfvvtefeattcSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEV 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1498 GLKELQGKLDESNTVLESQK---KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1574
Cdd:pfam05483  406 ELEELKKILAEDEKLLDEKKqfeKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKL 485

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1575 FDTQLA--------EYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletKELRRQLESLELEKSREV 1646
Cdd:pfam05483  486 KNIELTahcdklllENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKE----MNLRDELESVREEFIQKG 561

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1647 LSLKAQMNgASSRSGKGDEVESLDIETSLA-----------KINFLNSIIADMQQKNDALKAK 1698
Cdd:pfam05483  562 DEVKCKLD-KSEENARSIEYEVLKKEKQMKilenkcnnlkkQIENKNKNIEELHQENKALKKK 623
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1269-1704 5.58e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.55  E-value: 5.58e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS--------EQKLQQESQTSKEKLTEIQQSLQELQdsvkq 1340
Cdd:COG4913    291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEAQirgnggdrLEQLEREIERLERELEERERRRARLE----- 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1341 keELVQNLEEKVRESSSIIEAQNTKLNEsnvQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ---------- 1410
Cdd:COG4913    366 --ALLAALGLPLPASAEEFAALRAEAAA---LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnipa 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1411 -VQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL----QELLVKSQ------------ENEGNLQGESLA 1473
Cdd:COG4913    441 rLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAIERVLggfaLTLLVPPEhyaaalrwvnrlHLRGRLVYERVR 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1474 VTEKLQQLEQAN-GELKEALCQKENGLKE-LQGKLDESNTV--------------------LESQKKSHNEIQD------ 1525
Cdd:COG4913    521 TGLPDPERPRLDpDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdspeelrrhpraitragQVKGNGTRHEKDDrrrirs 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1526 ----------KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF------DTQLAEYQKVIDEM 1589
Cdd:COG4913    601 ryvlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvasaEREIAELEAELERL 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1590 DDAasvkSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLEleksREVLSLKAQMNGASSRsgkGDEVESL 1669
Cdd:COG4913    681 DAS----SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE----EELDELQDRLEAAEDL---ARLELRA 749

                          490       500       510
                   ....*....|....*....|....*....|....*...
gi 1834199290 1670 DIETSLAKI---NFLNSIIADMQQKNDALKAKVQTLET 1704
Cdd:COG4913    750 LLEERFAAAlgdAVERELRENLEERIDALRARLNRAEE 787
PTZ00121 PTZ00121
MAEBL; Provisional
 1154-1646 5.97e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.78  E-value: 5.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1154 KEKSFEESIKNLQEEVTKAKTENLELSTGTQTTikdlqerlEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIS 1233
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETG--------KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA 1148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1234 ATNAELSTVLEVLQAEKSEtnhIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEElEEKLKQAQQSEQKL 1313
Cdd:PTZ00121  1149 EDAKRVEIARKAEDARKAE---EARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEE-ERKAEEARKAEDAK 1224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1314 QQESQtskEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKK 1393
Cdd:PTZ00121  1225 KAEAV---KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1394 EKQlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGE--- 1470
Cdd:PTZ00121  1302 KKA--DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAkkk 1379

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1471 SLAVTEKLQQLEQANgELKEALCQKENGLKELQGKLDESNTVLESQKKShnEIQDKLEQAQQK--ERTLQEETSKLAEQ- 1547
Cdd:PTZ00121  1380 ADAAKKKAEEKKKAD-EAKKKAEEDKKKADELKKAAAAKKKADEAKKKA--EEKKKADEAKKKaeEAKKADEAKKKAEEa 1456

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1548 --LSQLKQANEELQKS--LQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKT 1623
Cdd:PTZ00121  1457 kkAEEAKKKAEEAKKAdeAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536

                          490       500
                   ....*....|....*....|...
gi 1834199290 1624 AYLETKELRRQLEslELEKSREV 1646
Cdd:PTZ00121  1537 DEAKKAEEKKKAD--ELKKAEEL 1557
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1103-1704 6.83e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 6.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1103 DEIAtGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEK---------SFEESIKNLQEEVTKAK 1173
Cdd:TIGR02169  160 DEIA-GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekrEYEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1174 TENLELSTGTQT-TIKDLQERLEITNAELQHKEKMASEDAQKIADL--------KTLVEAIQVANANISATNAELStvLE 1244
Cdd:TIGR02169  239 KEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeeqlrvKEKIGELEAEIASLERSIAEKE--RE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1245 VLQAEKSETNHIFELFEMEADM-NSERLIE----KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1319
Cdd:TIGR02169  317 LEDAEERLAKLEAEIDKLLAEIeELEREIEeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1320 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1399
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1400 EAAKLSGELQQVQE--------------------ANGDIKDSLVK-----VEELVKVlEEKLQAAT-------------- 1440
Cdd:TIGR02169  477 EYDRVEKELSKLQRelaeaeaqaraseervrggrAVEEVLKASIQgvhgtVAQLGSV-GERYATAIevaagnrlnnvvve 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1441 SQLDAQQATN--KELQ---------------------------------------------------ELLVKSQEN---- 1463
Cdd:TIGR02169  556 DDAVAKEAIEllKRRKagratflplnkmrderrdlsilsedgvigfavdlvefdpkyepafkyvfgdTLVVEDIEAarrl 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1464 ---------EGNLQGESLAVT---EKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQ 1531
Cdd:TIGR02169  636 mgkyrmvtlEGELFEKSGAMTggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1532 QKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAasvksalLEQLQNRVAELE 1611
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE---NVKSELKELEARIEELEED-------LHKLEEALNDLE 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1612 TALRQAndaqktaylETKELRRQLESLELEKSREVLSLkAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQK 1691
Cdd:TIGR02169  786 ARLSHS---------RIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE 855

                          730
                   ....*....|...
gi 1834199290 1692 NDALKAKVQTLET 1704
Cdd:TIGR02169  856 IENLNGKKEELEE 868
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 513-1169 7.50e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.32  E-value: 7.50e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  513 LKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSatpslqsilppdlpsddgalq 592
Cdd:TIGR02169  228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--------------------- 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKM---TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLK 669
Cdd:TIGR02169  287 EEQLRVKEKIgelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  670 EENEKQAQEAQAEFT---RKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEV 746
Cdd:TIGR02169  367 EDLRAELEEVDKEFAetrDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  747 TTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEK---------------------Q 805
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEErvrggraveevlkasiqgvhgT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  806 ISDLKQLAEQEKLVREMTE-NAINQIQLEKESIEQQLA--LKQ-----------NELEDFQKKQSESE--------VHLQ 863
Cdd:TIGR02169  527 VAQLGSVGERYATAIEVAAgNRLNNVVVEDDAVAKEAIelLKRrkagratflplNKMRDERRDLSILSedgvigfaVDLV 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  864 EI--KAQNTQK----DFELVESGESLKKLQQQLEQKTL-------------GH-----------------EKLQAALEEL 907
Cdd:TIGR02169  607 EFdpKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLegelfeksgamtgGSraprggilfsrsepaelQRLRERLEGL 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  908 KKEKETIIKEK---EQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEgsktVAKLHDEISQLKSQAEETQSELKS 984
Cdd:TIGR02169  687 KRELSSLQSELrriENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER----LEELEEDLSSLEQEIENVKSELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  985 TQSNLEAKSKQLEAANGSLEE-EAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKvnkEYAESR 1063
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK---EIQELQ 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1064 AEASDLQDKVKEITDTLHaELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDS 1143
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIE-NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          730       740
                   ....*....|....*....|....*....
gi 1834199290 1144 QTKLKAEGERKE---KSFEESIKNLQEEV 1169
Cdd:TIGR02169  919 LSELKAKLEALEeelSEIEDPKGEDEEIP 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 513-910 9.06e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.92  E-value: 9.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  513 LKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSlqsilppdlpsddgaLQ 592
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ---------------LS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKMTiqqkEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFS--LSECGIENLRRELELLKE 670
Cdd:TIGR02168  754 KELTELEAEIE----ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRaeLTLLNEEAANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  671 ENEKQAQEAQAEFTRK-LAEKSVEVLRLSSELQNLKATSDSLESERvnktdecEILQTEVRMRDEQIRELNQQLDEVTTQ 749
Cdd:TIGR02168  830 ERRIAATERRLEDLEEqIEELSEDIESLAAEIEELEELIEELESEL-------EALLNERASLEEALALLRSELEELSEE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  750 LNvqkadsSALDDMLRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLekqisdLKQLAEQEKLVREMTENAINQ 829
Cdd:TIGR02168  903 LR------ELESKRSELRRE--------LEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLTLEEAEALENK 962

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  830 IQLEKESIEQQLALKQNELEDFqkkqseSEVHL---QEIKAQNTQKDFelvesgeslkkLQQQLEQKTLGHEKLQAALEE 906
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKEL------GPVNLaaiEEYEELKERYDF-----------LTAQKEDLTEAKETLEEAIEE 1025


                   ....
gi 1834199290  907 LKKE 910
Cdd:TIGR02168 1026 IDRE 1029
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 693-1444 9.34e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.09  E-value: 9.34e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  693 EVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvQKADSSALDdmLRLQKEGTE 772
Cdd:pfam12128  242 EFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWK-EKRDELNGE--LSAADAAVA 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  773 EKSTLLEKTEKELVQSKEQAAKTLN-DKEQLEKQISDLKQLAEQEKLVremtENAINQIQLEKESIEQQLALKQN-ELED 850
Cdd:pfam12128  319 KDRSELEALEDQHGAFLDADIETAAaDQEQLPSWQSELENLEERLKAL----TGKHQDVTAKYNRRRSKIKEQNNrDIAG 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  851 FQKKQSesevhlqeikAQNTQKDFELVESGESLKKLQQQLeqktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSA 930
Cdd:pfam12128  395 IKDKLA----------KIREARDRQLAVAEDDLQALESEL------REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  931 ESEsaLKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELK-------STQSNLEAKSKQLEAANGSL 1003
Cdd:pfam12128  459 TPE--LLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRqasrrleERQSALDELELQLFPQAGTL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1004 EEEAKKSGHLLEQitklksEVGETQAALSSCHTD-----VESKTKQ---LEAANAALEKVNKEyaesraEASDLQDKVKE 1075
Cdd:pfam12128  537 LHFLRKEAPDWEQ------SIGKVISPELLHRTDldpevWDGSVGGelnLYGVKLDLKRIDVP------EWAASEEELRE 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1076 ITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQemlqKEKELQELRQQLqdsqdsqtklKAEGERKE 1155
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKN----ARLDLRRLFDEK----------QSEKDKKN 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1156 KSFEESIKNLQEEVTKAKTENLELStgtqttiKDLQERLEitnaelQHKEKMASEDAQKIADLKTLVEAIQVANANISAT 1235
Cdd:pfam12128  671 KALAERKDSANERLNSLEAQLKQLD-------KKHQAWLE------EQKEQKREARTEKQAYWQVVEGALDAQLALLKAA 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1236 NAelstvlevlqaeKSETNHIFELFEMEADMNSERlieKVTGIKEElkethlQLDERQKKFEELEEKLKQAQQSEQKLQQ 1315
Cdd:pfam12128  738 IA------------ARRSGAKAELKALETWYKRDL---ASLGVDPD------VIAKLKREIRTLERKIERIAVRRQEVLR 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1316 -----------ESQTSKEKLTEIQQSLQELQDSVKQKEElvqnleekvresssiieaqNTKLNESNVQLENKTSclKETQ 1384
Cdd:pfam12128  797 yfdwyqetwlqRRPRLATQLSNIERAISELQQQLARLIA-------------------DTKLRRAKLEMERKAS--EKQQ 855

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQLLESQKKEKQLQEEAAKLSgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLD 1444
Cdd:pfam12128  856 VRLSENLRGLRCEMSKLATLK-EDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVE 914
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 507-824 1.07e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 1.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  507 KKKLFPLKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPpDLPS 586
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK-ELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  587 DDGALQEEIAKLQEKM-TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELvsKDEALEKFSLSEcgienlrreL 665
Cdd:TIGR02169  766 RIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL--NRLTLEKEYLEK---------E 834

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  666 ELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDE 745
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK 914

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  746 VTTQLNVQKADSSALDDML----RLQKEGTEEKS-TLLEKTEKELVQSKEQAAKTL--------NDKEQLEKQISDLKql 812
Cdd:TIGR02169  915 KRKRLSELKAKLEALEEELseieDPKGEDEEIPEeELSLEDVQAELQRVEEEIRALepvnmlaiQEYEEVLKRLDELK-- 992

                          330
                   ....*....|..
gi 1834199290  813 AEQEKLVREMTE 824
Cdd:TIGR02169  993 EKRAKLEEERKA 1004
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1195-1641 1.55e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.86  E-value: 1.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1195 EITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANIsatnAELSTVLEVLQAEKSETNHIFELFEMEADMNS-ERLIE 1273
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL----EELEAELEELREELEKLEKLLQLLPLYQELEAlEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1274 KVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQS-EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1352
Cdd:COG4717    143 ELPERLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1353 RESSSIIEaqntklnesnvQLENKtsclketqdqlLESQKKEKQLQEEAAKLS--GELQQVQEANGDIKDSLVKVEELVK 1430
Cdd:COG4717    223 EELEEELE-----------QLENE-----------LEAAALEERLKEARLLLLiaAALLALLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1511 TVLEsQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEfDTQLAEYQKVIDEMD 1590
Cdd:COG4717    361 EELQ-LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLE-ALDEEELEEELEELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1591 DAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETK--ELRRQLESLELE 1641
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLEEDGELAELLQEleELKAELRELAEE 491
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 767-1000 1.80e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.70  E-value: 1.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  767 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDL-KQLAEQEKLVREmTENAINQIQLEKESIEQQLALKQ 845
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALeRRIAALARRIRA-LEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  846 NELEDFQKKQSESEVHLQEIKAQNT------QKDFELVESG--------ESLKKLQQQLEQKTLGHEKLQAALEELKKEK 911
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPlalllsPEDFLDAVRRlqylkylaPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  912 ETIIKEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEA 991
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARL------------------EKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ....*....
gi 1834199290  992 KSKQLEAAN 1000
Cdd:COG4942    239 AAERTPAAG 247
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1466-1705 1.86e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.03  E-value: 1.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1466 NLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLA 1545
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1546 EQLSQLKQANEELQKSLQQKQLLLEkgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAY 1625
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEELE---ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1626 LETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETL 1705
Cdd:COG1196    393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 772-1642 1.87e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 63.05  E-value: 1.87e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  772 EEKSTLLEKT---EKELVQSKEQAAktlNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQ--LALKQN 846
Cdd:COG3096    278 NERRELSERAlelRRELFGARRQLA---EEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekIERYQE 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  847 ELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQL--------EQKTLGHEKLQA--ALEELK-------- 908
Cdd:COG3096    355 DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLadyqqaldVQQTRAIQYQQAvqALEKARalcglpdl 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  909 -----KEKETIIKEKEQELQQ----LQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISqlKSQAEETQ 979
Cdd:COG3096    435 tpenaEDYLAAFRAKEQQATEevleLEQKLSVADAARRQF---------------EKAYELVCKIAGEVE--RSQAWQTA 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAANGSLEEEAKksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEY 1059
Cdd:COG3096    498 RELLRRYRSQQALAQRLQQLRAQLAELEQ----RLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1060 AESRAEASDLQDKVKEITdTLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKAD--AWSQEMLQKEKELQELRQQL 1137
Cdd:COG3096    574 AEAVEQRSELRQQLEQLR-ARIKELAARAPAWLAAQDALERLREQS---GEALADSQEvtAAMQQLLEREREATVERDEL 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1138 QdsqdsqtklkaegERKEkSFEESIKNLQEevtKAKTENLELSTgtqttikdLQERLeitNAELQHK--EKMASEDAQKI 1215
Cdd:COG3096    650 A-------------ARKQ-ALESQIERLSQ---PGGAEDPRLLA--------LAERL---GGVLLSEiyDDVTLEDAPYF 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1216 -ADLKTLVEAIQVAnanisatnaELSTVLEVLQAEKSETNHIFeLFEMEADMNSERLIEKvtgikEELKETHL-QLDERQ 1293
Cdd:COG3096    702 sALYGPARHAIVVP---------DLSAVKEQLAGLEDCPEDLY-LIEGDPDSFDDSVFDA-----EELEDAVVvKLSDRQ 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1294 ---KKFEEL--------EEKLKqaqqseqKLQQESQTSKEKLTEIQQSLQELQdsvkqkeELVQNLEEKVRESSSII--- 1359
Cdd:COG3096    767 wrySRFPEVplfgraarEKRLE-------ELRAERDELAEQYAKASFDVQKLQ-------RLHQAFSQFVGGHLAVAfap 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1360 --EAQNTKLNESNVQLEnktsclketqDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIkdSLVK---VEELVKVLEE 1434
Cdd:COG3096    833 dpEAELAALRQRRSELE----------RELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQA--NLLAdetLADRLEELRE 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1435 KLQAATSQ---LDAQQATNKELQELLVKSQ---ENEGNLQGESLAVTEKLQQLEQANGELKEALCQKEN-GLKELQGKLD 1507
Cdd:COG3096    901 ELDAAQEAqafIQQHGKALAQLEPLVAVLQsdpEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHfSYEDAVGLLG 980

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1508 ESNTVLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekgNEFDTQLAEYQKVID 1587
Cdd:COG3096    981 ENSDLNEK-------LRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTL---QELEQELEELGVQAD 1050

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1588 emDDAAsvksallEQLQNRVAELETALRQaNDAQKTaYLETKELRRQLESLELEK 1642
Cdd:COG3096   1051 --AEAE-------ERARIRRDELHEELSQ-NRSRRS-QLEKQLTRCEAEMDSLQK 1094
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1233-1574 2.37e-09

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 62.45  E-value: 2.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1233 SATNAELSTVLEVLQAEKS--ETNHIFELFEMEAdmnserlieKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSE 1310
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKqmELEHKRARIELEK---------KASALKRQLDRESDRNQELQKRIRLLEKREAEAEEAL 71

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1311 QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLES 1390
Cdd:pfam05557   72 REQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEA 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1391 QKKEKQLQEEAAKLSGELQQVQEANGDIKdSLVKVEELVKVLEEKLqAATSQLDAQQATNKELQELLVKSQENEGNLQGE 1470
Cdd:pfam05557  152 EQLRQNLEKQQSSLAEAEQRIKELEFEIQ-SQEQDSEIVKNSKSEL-ARIPELEKELERLREHNKHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1471 SLAVTEKLQQLEQANGELKEALCQKENGLKELQG--KLDESNTVlesQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1548
Cdd:pfam05557  230 VEDLKRKLEREEKYREEAATLELEKEKLEQELQSwvKLAQDTGL---NLRSPEDLSRRIEQLQQREIVLKEENSSLTSSA 306

                          330       340
                   ....*....|....*....|....*....
gi 1834199290 1549 SQLKQANEELQ---KSLQQKQLLLEKGNE 1574
Cdd:pfam05557  307 RQLEKARRELEqelAQYLKKIEDLNKKLK 335
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 506-1590 2.61e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 62.76  E-value: 2.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  506 DKKKLFPLKARIVElESALDN--ERKKTEELQCSIDEAQfcgDEL-NAQSQVYKEKIHDLESKITKLVSATPSLQSILpp 582
Cdd:TIGR01612  672 DIDALYNELSSIVK-ENAIDNteDKAKLDDLKSKIDKEY---DKIqNMETATVELHLSNIENKKNELLDIIVEIKKHI-- 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  583 dlpsdDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRenvKYlNEQIATLQSELvskdealekfslsecgieNLR 662
Cdd:TIGR01612  746 -----HGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELN---KY-KSKISEIKNHY------------------NDQ 798

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  663 RELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECeilQTEVRMRDEQIREL-NQ 741
Cdd:TIGR01612  799 INIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNC---KEKIDSEHEQFAELtNK 875

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  742 QLDEVT-TQLNVQKA---DSSALDDMLRLQKEGTEEKSTLLEKTEK--ELVQSKEQAAKTLNDK-----EQLEKQISDLK 810
Cdd:TIGR01612  876 IKAEISdDKLNDYEKkfnDSKSLINEINKSIEEEYQNINTLKKVDEyiKICENTKESIEKFHNKqnilkEILNKNIDTIK 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  811 QLAEQEKLVREMTENA-INQI-QLEKesieqqlALKQNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQ 887
Cdd:TIGR01612  956 ESNLIEKSYKDKFDNTlIDKInELDK-------AFKDASLNDYEAKNNELIKYFNDLKANlGKNKENMLYHQFDEKEKAT 1028

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  888 QQLEQKTlghEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESesalkvvQVQLEQLQQQAAASGEEGSKTVAKLHDE 967
Cdd:TIGR01612 1029 NDIEQKI---EDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIEL-------LNKEILEEAEINITNFNEIKEKLKHYNF 1098

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  968 ISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSghlleqitklksevgetqaalsschtdvESKTKQLEA 1047
Cdd:TIGR01612 1099 DDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKS----------------------------ENYIDEIKA 1150

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1048 ANAALEKVnkeyaesrAEASDLQDKVKEITDTLHaELQAERSSSSALHTKLSKFSDEIATGHKELTSkadawsqemLQKE 1127
Cdd:TIGR01612 1151 QINDLEDV--------ADKAISNDDPEEIEKKIE-NIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS---------LEEV 1212

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1128 KELQeLRQQLQDSQDSQTKLKAEGERKE---KSFEESIKNLQEevTKAKTENLELSTGTQTTIKDLQERLEITNAELQHK 1204
Cdd:TIGR01612 1213 KGIN-LSYGKNLGKLFLEKIDEEKKKSEhmiKAMEAYIEDLDE--IKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDH 1289

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1205 EKMASEDAQKIADLKTLVEAIQVAN---ANISATNAELSTVLEVLQAEKSETN----HIFELFEMEADMNSERLIEKVTG 1277
Cdd:TIGR01612 1290 HIISKKHDENISDIREKSLKIIEDFseeSDINDIKKELQKNLLDAQKHNSDINlylnEIANIYNILKLNKIKKIIDEVKE 1369

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQLDERQKKFEELEEKLKQAQQSEQ-KLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1356
Cdd:TIGR01612 1370 YTKEIEENNKNIKDELDKSEKLIKKIKDDINLEEcKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENN 1449

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1357 siieaQNTKLNESNVQL-ENKTSCLKETQ------------DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLV 1423
Cdd:TIGR01612 1450 -----ENVLLLFKNIEMaDNKSQHILKIKkdnatndhdfniNELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVT 1524

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1424 KVEELVKVLEEKLQAATSQLDAQQATN--KELQELLV----KSQENEGNLQGESLAVTEKLQQLEQANgelkEALCQKEN 1497
Cdd:TIGR01612 1525 ELLNKYSALAIKNKFAKTKKDSEIIIKeiKDAHKKFIleaeKSEQKIKEIKKEKFRIEDDAAKNDKSN----KAAIDIQL 1600

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1498 GLKELQGKLDESNTVlesqKKSHNEIQDKLEQAQQKERTLQEET--SKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1575
Cdd:TIGR01612 1601 SLENFENKFLKISDI----KKKINDCLKETESIEKKISSFSIDSqdTELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676

                         1130
                   ....*....|....*
gi 1834199290 1576 DTQLAEYQKVIDEMD 1590
Cdd:TIGR01612 1677 DELDSEIEKIEIDVD 1691
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1272-1652 2.83e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.09  E-value: 2.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1272 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQtSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1351
Cdd:COG4717     73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKLLQLLPLYQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1352 VRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1431
Cdd:COG4717    152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1432 LEEKL--QAATSQLDAQQATNKELQELLV---------KSQENEGNLQGESLAV------------TEKLQQLEQANG-E 1487
Cdd:COG4717    232 LENELeaAALEERLKEARLLLLIAAALLAllglggsllSLILTIAGVLFLVLGLlallflllarekASLGKEAEELQAlP 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1488 LKEALCQKE--NGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETS--KLAEQLSQLKQANEE----LQ 1559
Cdd:COG4717    312 ALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELeqEIAALLAEAGVEDEEelraAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1560 KSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASvksalLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLEslE 1639
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEALD-----EEELEEELEELEEELEELEEELEELREELAELEAELE--Q 464

                          410
                   ....*....|...
gi 1834199290 1640 LEKSREVLSLKAQ 1652
Cdd:COG4717    465 LEEDGELAELLQE 477
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1122-1634 3.21e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.05  E-value: 3.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1122 EMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIknlQEEVTKAKTENlelstGTQTTIKDLQERLEITNAEL 1201
Cdd:pfam05483  100 ELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEI---QENKDLIKENN-----ATRHLCNLLKETCARSAEKT 171

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1202 QHKEKMASEDAQKIADLKTLVEAIQVA--NANISATNAELSTVLEvLQAEKSETNHIFELFEMEADMNSER---LIEKVT 1276
Cdd:pfam05483  172 KKYEYEREETRQVYMDLNNNIEKMILAfeELRVQAENARLEMHFK-LKEDHEKIQHLEEEYKKEINDKEKQvslLLIQIT 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1277 GIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1356
Cdd:pfam05483  251 EKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLT 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1357 SIIEAQNTKLNESN-------VQLENKTSCLKE---TQDQLLEsqKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVE 1426
Cdd:pfam05483  331 EEKEAQMEELNKAKaahsfvvTEFEATTCSLEEllrTEQQRLE--KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1427 ELVKVLEEKlqaaTSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGK- 1505
Cdd:pfam05483  409 ELKKILAED----EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEk 484

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1506 ------LDESNTVLESQKKSHNEIQD---KLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQ-KQLLLEKGNEF 1575
Cdd:pfam05483  485 lknielTAHCDKLLLENKELTQEASDmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESvREEFIQKGDEV 564

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1576 DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQ 1634
Cdd:pfam05483  565 KCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKK 623
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1292-1704 3.27e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.96  E-value: 3.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1292 RQKKFEELEEKLKQAQ----QSEQKL-------------------------QQESQ------TSKEKLTEIQQSLQELQD 1336
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKnelkNKEKELknldknlnkdeekinnsnnkikileQQIKDlndklkKNKDKINKLNSDLSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1337 SVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANG 1416
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNID 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1417 DIKDSLVKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALC 1493
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1494 QKENGLKELQGKLDESN----------TVLESQKKS--HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1561
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEkqlnqlkseiSDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1562 LQQKQLlleKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDaqktaylETKELRRQLESLELE 1641
Cdd:TIGR04523  351 LTNSES---ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK-------LNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1642 KSrevLSLKAQMNGASSRSGKGDEVESLDIETSLAK--INFLNSIIADMQQKNDALKAKVQTLET 1704
Cdd:TIGR04523  421 KE---LLEKEIERLKETIIKNNSEIKDLTNQDSVKEliIKNLDNTRESLETQLKVLSRSINKIKQ 482
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 979-1665 3.56e-09

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 62.28  E-value: 3.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  979 QSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTdvesKTKQLEAANAALEKvnke 1058
Cdd:COG3096    353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQT----RAIQYQQAVQALEK---- 424

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1059 yAESRAEASDL-QDKVKEITDTLHAELQAERSSSSALHTKLSkFSDEIATGHKEL----------TSKADAWS--QEMLq 1125
Cdd:COG3096    425 -ARALCGLPDLtPENAEDYLAAFRAKEQQATEEVLELEQKLS-VADAARRQFEKAyelvckiageVERSQAWQtaRELL- 501

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1126 keKELQELRQQLQDSQDSQTKLkAEGERKEKSfEESIKNLQEEVTKAKTENLElstgTQTTIKDLQERLEITNAELqhkE 1205
Cdd:COG3096    502 --RRYRSQQALAQRLQQLRAQL-AELEQRLRQ-QQNAERLLEEFCQRIGQQLD----AAEELEELLAELEAQLEEL---E 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1206 KMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFElfemeadmNSERLIEKVTGIKEELKET 1285
Cdd:COG3096    571 EQAAEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEALA--------DSQEVTAAMQQLLEREREA 642

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1286 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEK-----LTEIQQ--SLQE----------------LQDSVKQKE 1342
Cdd:COG3096    643 TVERDELAARKQALESQIERLSQPGGAEDPRLLALAERlggvlLSEIYDdvTLEDapyfsalygparhaivVPDLSAVKE 722

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1343 ELvQNLEEkVRESSSIIEAQNTKLNES--NVQLENKTSCLKETQDQLLESQ----------KKEKQLQ----------EE 1400
Cdd:COG3096    723 QL-AGLED-CPEDLYLIEGDPDSFDDSvfDAEELEDAVVVKLSDRQWRYSRfpevplfgraAREKRLEelraerdelaEQ 800

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1401 AAKLSGELQQVQEANGDIKDSLVK---------VEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQG-- 1469
Cdd:COG3096    801 YAKASFDVQKLQRLHQAFSQFVGGhlavafapdPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKll 880

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1470 --------ESLAvtEKLQQLEQANGELKEA---LCQKENGLKELQGKLDesntVLESQKKSHNEIQDKLEQAQQKERTLQ 1538
Cdd:COG3096    881 pqanlladETLA--DRLEELREELDAAQEAqafIQQHGKALAQLEPLVA----VLQSDPEQFEQLQADYLQAKEQQRRLK 954

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1539 -------------------------EETSKLAEQL-SQLKQANEELQKS-LQQKQLllekgnefDTQLAEYQKVIDEMDD 1591
Cdd:COG3096    955 qqifalsevvqrrphfsyedavgllGENSDLNEKLrARLEQAEEARREArEQLRQA--------QAQYSQYNQVLASLKS 1026

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1592 AASVKSALLEQLQNRVAELEtaLRQANDAQKTAYLETKELRRQLESL-----ELEKSREVlsLKAQMNGASSRSGKGDE 1665
Cdd:COG3096   1027 SRDAKQQTLQELEQELEELG--VQADAEAEERARIRRDELHEELSQNrsrrsQLEKQLTR--CEAEMDSLQKRLRKAER 1101
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1269-1647 4.96e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 61.32  E-value: 4.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK--EKLTEIQQSLQELQ---DSVKQKEE 1343
Cdd:COG4717     77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPerlEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1344 LVQNLEEKVRESSSIIEAQNTKLNESNVQLENKT-SCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSL 1422
Cdd:COG4717    157 ELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1423 VKVEELVKVLEEK-LQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALcQKENGLKE 1501
Cdd:COG4717    237 EAAALEERLKEARlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL-QALPALEE 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1502 LQGKldESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQkslqQKQLLLEKGNEFDTQLAE 1581
Cdd:COG4717    316 LEEE--ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQE----IAALLAEAGVEDEEELRA 389

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1582 YQKVIDEMDDAAsvksALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVL 1647
Cdd:COG4717    390 ALEQAEEYQELK----EELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
778-1514 5.80e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.47  E-value: 5.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  778 LEKTEKELVQSKEQAaKTLND-KEQLEKQISDLKQLAEQEKLVREMT----ENAINQIQLEKESIEQQLALKQNELEDFQ 852
Cdd:COG4913    237 LERAHEALEDAREQI-ELLEPiRELAERYAAARERLAELEYLRAALRlwfaQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  853 KKQSESEVHLQEIKAQNTQKDfelvesGESLKKLQQQLEQKTLGHEKLQAALEELkkeketiikekEQELQQLQSKSAES 932
Cdd:COG4913    316 ARLDALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERERRRARL-----------EALLAALGLPLPAS 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  933 ESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE---LKSTQSNLEAKS----KQLEAANGSLEE 1005
Cdd:COG4913    379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEiasLERRKSNIPARLlalrDALAEALGLDEA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1006 EAKKSGHLLEqitkLKSEVGETQAA----LSSCHTD--VESktkqlEAANAALEKVNKEYAESRaeasdLQ-DKVKEITD 1078
Cdd:COG4913    459 ELPFVGELIE----VRPEEERWRGAiervLGGFALTllVPP-----EHYAAALRWVNRLHLRGR-----LVyERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1079 TLHAELQAERSSSSALHTKLSKFSDEIatgHKELTSKADAWSQEmlqkekELQELRQqlqdsqdsqtklkaegerkeksf 1158
Cdd:COG4913    525 DPERPRLDPDSLAGKLDFKPHPFRAWL---EAELGRRFDYVCVD------SPEELRR----------------------- 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1159 eesiknlqeeVTKAKTENLELSTGTQTTIKDLQERLEitnAELQhkekMASEDAQKIADLKTLVEAIQVANANISATNAE 1238
Cdd:COG4913    573 ----------HPRAITRAGQVKGNGTRHEKDDRRRIR---SRYV----LGFDNRAKLAALEAELAELEEELAEAEERLEA 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1239 LSTVLEVLQAEKSETNHIFELFEMEADMNSerLIEKVTGIKEELKethlQLDERQKKFEELEEKLKQAQQSEQKLQQESQ 1318
Cdd:COG4913    636 LEAELDALQERREALQRLAEYSWDEIDVAS--AEREIAELEAELE----RLDASSDDLAALEEQLEELEAELEELEEELD 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1319 TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVResssiiEAQNTKLnesnvqlenktsclketqDQLLESQKKEKQLQ 1398
Cdd:COG4913    710 ELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR------LELRALL------------------EERFAAALGDAVER 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1399 EEAAKLSGELQQVQEANGDikdslvKVEELVKVLEEKLQ---AATSQLDAQQATNKELQELLVKsqenegnLQGESLAVT 1475
Cdd:COG4913    766 ELRENLEERIDALRARLNR------AEEELERAMRAFNRewpAETADLDADLESLPEYLALLDR-------LEEDGLPEY 832

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1476 EK--LQQLEQANGELKEALCQK-ENGLKELQGKLDESNTVLE 1514
Cdd:COG4913    833 EErfKELLNENSIEFVADLLSKlRRAIREIKERIDPLNDSLK 874
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 906-1570 6.13e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.22  E-value: 6.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  906 ELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGS-------KTVAKLHDEISQL------- 971
Cdd:TIGR00606  109 EFKTLEGVITRYKHGEKVSLSSKCAEIDREMISHLGVSKAVLNNVIFCHQEDSnwplsegKALKQKFDEIFSAtryikal 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  972 ----------KSQAEETQSELKSTQSNLEAKSK---QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHtDV 1038
Cdd:TIGR00606  189 etlrqvrqtqGQKVQEHQMELKYLKQYKEKACEirdQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIM-KL 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1039 ESKTKQLEAANAALEKVNKEYAESRAEA-SDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKAD 1117
Cdd:TIGR00606  268 DNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLV 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1118 AWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTEnlELSTGTQTTikdlqerleit 1197
Cdd:TIGR00606  348 EQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQED--EAKTAAQLC----------- 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1198 nAELQHKEKMASEDAQKIADLKT-LVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKvt 1276
Cdd:TIGR00606  415 -ADLQSKERLKQEQADEIRDEKKgLGRTIELKKEILEKKQEELKFVIKELQ---------------QLEGSSDRILEL-- 476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1277 giKEELKETHLQLDERQKKfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESS 1356
Cdd:TIGR00606  477 --DQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIR 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1357 SIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKL 1436
Cdd:TIGR00606  553 KIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKL 628

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1437 QAATSQlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE--------------QANGELKEALCQKENGLKEL 1502
Cdd:TIGR00606  629 FDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTdenqsccpvcqrvfQTEAELQEFISDLQSKLRLA 707

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1503 QGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLE 1570
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLG 775
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 125-185 9.37e-09

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 60.47  E-value: 9.37e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290  125 IGQRVWLGGTRpGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSR 185
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIR 65
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
590-1098 1.12e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 60.31  E-value: 1.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  590 ALQEEIAKLQEkmtiQQKEVESRIAEQLEEEQRLRENVKYL-NEQIATLQSELVSKDEALEKfslsecgienlrreleLL 668
Cdd:COG4913    299 ELRAELARLEA----ELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEE----------------RE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  669 KEENEKQAQEAQAEFTRKLAEKSVEVLRlsselQNLKATSDSLESERvnktdecEILQTEVRMRDEQIRELNQQLDEVTT 748
Cdd:COG4913    359 RRRARLEALLAALGLPLPASAEEFAALR-----AEAAALLEALEEEL-------EALEEALAEAEAALRDLRRELRELEA 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  749 QLNVQKADSSALD-DMLRLQKEGTEEkstlLEKTEK------ELVQSKEQAAKTLNDKEQL-----------EKQISDLK 810
Cdd:COG4913    427 EIASLERRKSNIPaRLLALRDALAEA----LGLDEAelpfvgELIEVRPEEERWRGAIERVlggfaltllvpPEHYAAAL 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  811 QLAEQEKL--------VREMTENAINQiQLEKESIEQQLALKQNELEDFqkkqsesevhLQEIKAQntQKDFELVESGES 882
Cdd:COG4913    503 RWVNRLHLrgrlvyerVRTGLPDPERP-RLDPDSLAGKLDFKPHPFRAW----------LEAELGR--RFDYVCVDSPEE 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  883 LKKLQQ------QLEQKTLGHEK-----------L----QAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQV 941
Cdd:COG4913    570 LRRHPRaitragQVKGNGTRHEKddrrrirsryvLgfdnRAKLAALEAE----LAELEEELAEAEERLEALEAELDALQE 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  942 QLEQLQQQAAASGEEgsKTVAKLHDEISQLksqaEETQSELKSTQSNLEAKSKQLEAANGSLEEeakksghLLEQITKLK 1021
Cdd:COG4913    646 RREALQRLAEYSWDE--IDVASAEREIAEL----EAELERLDASSDDLAALEEQLEELEAELEE-------LEEELDELK 712

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1022 SEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKL 1098
Cdd:COG4913    713 GEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 523-1628 1.17e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 60.45  E-value: 1.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  523 ALDNERKKTEELqcsIDE--AQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILppdlpSDDGALQEEIAKLQE 600
Cdd:TIGR01612 1133 ALEEIKKKSENY---IDEikAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIY-----DEIKKLLNEIAEIEK 1204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  601 KMTIQQ----------KEVESRIAEQLEEEQRLRENVkylneqIATLQSELVSKDEALEKFSLSECGIENLRRELELLKE 670
Cdd:TIGR01612 1205 DKTSLEevkginlsygKNLGKLFLEKIDEEKKKSEHM------IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMET 1278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  671 ENEKQAQEAQAEFTRKLAEKSVEVLRLSSelqnLKATSDSLESERVNktDECEILQTEVRMRDEQIRELNQQLDEVTTQL 750
Cdd:TIGR01612 1279 FNISHDDDKDHHIISKKHDENISDIREKS----LKIIEDFSEESDIN--DIKKELQKNLLDAQKHNSDINLYLNEIANIY 1352

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  751 NVQKadssalddmlrlqkegteekstlLEKTEKELVQSKEQAaktlNDKEQLEKQISDlkQLAEQEKLVREMTENAinQI 830
Cdd:TIGR01612 1353 NILK-----------------------LNKIKKIIDEVKEYT----KEIEENNKNIKD--ELDKSEKLIKKIKDDI--NL 1401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  831 QLEKESIEQQLALKqnELEDFQKKQSESEVHlqeIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKE 910
Cdd:TIGR01612 1402 EECKSKIESTLDDK--DIDECIKKIKELKNH---ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDN 1476

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  911 KETIIKEKEQELQQLQSKSaeseSALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLksqaeETQSELKSTQSNLE 990
Cdd:TIGR01612 1477 ATNDHDFNINELKEHIDKS----KGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-----AIKNKFAKTKKDSE 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  991 AKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVnkeyaesraeaSDLQ 1070
Cdd:TIGR01612 1548 IIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKI-----------SDIK 1616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1071 DKVKE-ITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAwSQEMLQKEKELQELRQQLQdsqdsqtKLKA 1149
Cdd:TIGR01612 1617 KKINDcLKETESIEKKISSFSIDSQDTELKENGDNLNSLQEFLESLKDQ-KKNIEDKKKELDELDSEIE-------KIEI 1688

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1150 EGERKEKSFEESIKNLQEEVTKAKTENLE-LSTGTQTTIKDLQERLEITNAE-LQHKEKMASEDAQKIADLKTLVEAIQV 1227
Cdd:TIGR01612 1689 DVDQHKKNYEIGIIEKIKEIAIANKEEIEsIKELIEPTIENLISSFNTNDLEgIDPNEKLEEYNTEIGDIYEEFIELYNI 1768

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1228 ANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNS---ERLIEKVTGIKEELKEthlQLDERQKKFEELEEKLK 1304
Cdd:TIGR01612 1769 IAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKKSKSyldDIEAKEFDRIINHFKK---KLDHVNDKFTKEYSKIN 1845

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1305 QAQQSEQKLQQESQTSKEKlteiqqslQELQDSVKQKEELVQNLEEKV-----RESSSIIEAQNTKLNESNVQLENKT-- 1377
Cdd:TIGR01612 1846 EGFDDISKSIENVKNSTDE--------NLLFDILNKTKDAYAGIIGKKyysykDEAEKIFINISKLANSINIQIQNNSgi 1917

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1378 SCLKETQDQLLESQKKEKqlqEEAAKLSGELQQVQEANGDIKDSLVKVEELVKvleeklqaatsqldAQQATNKELQELL 1457
Cdd:TIGR01612 1918 DLFDNINIAILSSLDSEK---EDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFK--------------KSQDLHKKEQDTL 1980

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1458 vksqenegNLQGESLAVTEKLQQLEQANGELKEALCQKE---NGLKELQGKLDESN----------TVLESQKksHNEIQ 1524
Cdd:TIGR01612 1981 --------NIIFENQQLYEKIQASNELKDTLSDLKYKKEkilNDVKLLLHKFDELNklscdsqnydTILELSK--QDKIK 2050

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1525 DKLEQAQQKERTL--QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKsalLEQ 1602
Cdd:TIGR01612 2051 EKIDNYEKEKEKFgiDFDVKAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTE---IKI 2127

                         1130      1140
                   ....*....|....*....|....*.
gi 1834199290 1603 LQNRVAELETALRQANDAQKTAYLET 1628
Cdd:TIGR01612 2128 IEDKIIEKNDLIDKLIEMRKECLLFS 2153
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1165-1655 1.25e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 60.24  E-value: 1.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1165 LQEEVTKAKTENLELST------GTQTTIKDLQERLEITNAELqhKEKMASEDAQkiadlktlveaiqvANANISATNAE 1238
Cdd:pfam12128  246 LQQEFNTLESAELRLSHlhfgykSDETLIASRQEERQETSAEL--NQLLRTLDDQ--------------WKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1239 LSTVLEVLQAEKSEtnhiFELFEMEADMNSERLIEKVTGIKEelkethlQLDERQKKFEELEEKLKQAQQSEQKLQQESQ 1318
Cdd:pfam12128  310 LSAADAAVAKDRSE----LEALEDQHGAFLDADIETAAADQE-------QLPSWQSELENLEERLKALTGKHQDVTAKYN 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1319 TSKEKLteiqqSLQELQDSVKQKEELVQNLEEKVR---ESSSIIEAQNTKLNEsnvqlenktsclkETQDQLLESQKKEK 1395
Cdd:pfam12128  379 RRRSKI-----KEQNNRDIAGIKDKLAKIREARDRqlaVAEDDLQALESELRE-------------QLEAGKLEFNEEEY 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1396 QLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQqatnKELQELLVKSQENEGNLQGESLAVT 1475
Cdd:pfam12128  441 RLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQ----SELRQARKRRDQASEALRQASRRLE 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1476 EKLQQLEQAN-------GELKEALCQKENGLKELQGKL---------------------DESN---TVLESQKKSHNEIQ 1524
Cdd:pfam12128  517 ERQSALDELElqlfpqaGTLLHFLRKEAPDWEQSIGKVispellhrtdldpevwdgsvgGELNlygVKLDLKRIDVPEWA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1525 DKLEQAQQK----ERTLQEETSKLAEQLSQLKQANEELQKS---------------LQQKQLLLEKGNEFDT---QLAEY 1582
Cdd:pfam12128  597 ASEEELRERldkaEEALQSAREKQAAAEEQLVQANGELEKAsreetfartalknarLDLRRLFDEKQSEKDKknkALAER 676

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1583 QK-VIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRR-QLESLELEKSREVLSLKAQMNG 1655
Cdd:pfam12128  677 KDsANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDaQLALLKAAIAARRSGAKAELKA 751
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 506-830 1.49e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  506 DKKKLFPLKARIVEL--------------ESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVS 571
Cdd:TIGR02169  672 EPAELQRLRERLEGLkrelsslqselrriENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  572 ATPSLQSILpPDLPSDDGALQEEIAKLQEKM-TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEK 650
Cdd:TIGR02169  752 EIENVKSEL-KELEARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  651 FSLSECGIENLRRELELLKEENEKQAQEAQA---EFTRKLAEKSVEVLRLSSELQNLKATSDSLESERvnktdecEILQT 727
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGkkeELEEELEELEAALRDLESRLGDLKKERDELEAQL-------RELER 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  728 EVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTL------LEKTEKEL----------VQSKEQ 791
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLedvqaeLQRVEEEIralepvnmlaIQEYEE 983

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1834199290  792 AAKTLND----KEQLEKQISDLKQLAEQ-EKLVREMTENAINQI 830
Cdd:TIGR02169  984 VLKRLDElkekRAKLEEERKAILERIEEyEKKKREVFMEAFEAI 1027
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1281-1491 1.59e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 58.69  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1281 ELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIE 1360
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1361 AQNTKLNESNVQLENKT-----------SCLKETQDQLLESQKKEK-QLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1428
Cdd:COG3883     97 RSGGSVSYLDVLLGSESfsdfldrlsalSKIADADADLLEELKADKaELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1429 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEA 1491
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1385-1656 1.65e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQLLEsqkkEKQLQEEAAKLSGELQQVQEAngdiKDSLVKVEELVKVLE------EKLQAATSQLDAQQATnKELQELLV 1458
Cdd:COG4913    215 EYMLE----EPDTFEAADALVEHFDDLERA----HEALEDAREQIELLEpirelaERYAAARERLAELEYL-RAALRLWF 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1459 KSQENEgnlqgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDEsntvLESQKKSHNeiQDKLEQAQQKERTLQ 1538
Cdd:COG4913    286 AQRRLE--------LLEAELEELRAELARLEAELERLEARLDALREELDE----LEAQIRGNG--GDRLEQLEREIERLE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1539 EETSKLAEQLSQLKQANEELqkslqqkqlllekGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAN 1618
Cdd:COG4913    352 RELEERERRRARLEALLAAL-------------GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1834199290 1619 DaqktaylETKELRRQLESLELEKS---REVLSLKAQMNGA 1656
Cdd:COG4913    419 R-------ELRELEAEIASLERRKSnipARLLALRDALAEA 452
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1434-1663 1.89e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 1.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1434 EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVL 1513
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1514 ESQKKSHNEIQDKLEQAQQKERTL----QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEM 1589
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLAlllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1590 DDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKG 1663
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 734-937 1.90e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 1.90e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  734 EQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQisdlkqLA 813
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE------LE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  814 EQEKLVREMtenaINQIQLEKESIEQQLALKQNELEDFQKKQSesevHLQEIKAQNTQKDFELVESGESLKKLQQQLEQK 893
Cdd:COG4942    101 AQKEELAEL----LRALYRLGRQPPLALLLSPEDFLDAVRRLQ----YLKYLAPARREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1834199290  894 TLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 937
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELA 216
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1155-1659 2.28e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1155 EKSFEESIKNLQEEVtkaktENLElstGTQTTIKDLQERLEITNAELQHKEKMAsEDAQKIADLKTLVEAIQVANANISA 1234
Cdd:COG4913    220 EPDTFEAADALVEHF-----DDLE---RAHEALEDAREQIELLEPIRELAERYA-AARERLAELEYLRAALRLWFAQRRL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1235 tnAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIE-----------KVTGIKEELKETHLQLDERQKKFEELEEKL 1303
Cdd:COG4913    291 --ELLEAELEELRAELARLEAELERLEARLDALREELDEleaqirgnggdRLEQLEREIERLERELEERERRRARLEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1304 KQAQQSE-------QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEelvQNLEEKVRESSSIIEAqntklnesnvqLENK 1376
Cdd:COG4913    369 AALGLPLpasaeefAALRAEAAALLEALEEELEALEEALAEAEAAL---RDLRRELRELEAEIAS-----------LERR 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1377 TSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS------------LV------KVEELV--------- 1429
Cdd:COG4913    435 KSNIPARLLALRDALAEALGLDEAELPFVGELIEVRPEEERWRGAiervlggfaltlLVppehyaAALRWVnrlhlrgrl 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1430 ---KVLEEKLQAATSQLDAQQATNK----------ELQELLVKSQ-----ENEGNLQGESLAVTEKLQ------------ 1479
Cdd:COG4913    515 vyeRVRTGLPDPERPRLDPDSLAGKldfkphpfraWLEAELGRRFdyvcvDSPEELRRHPRAITRAGQvkgngtrhekdd 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1480 --------QLEQANGELKEALcQKEngLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE---------RTLQEETS 1542
Cdd:COG4913    595 rrrirsryVLGFDNRAKLAAL-EAE--LAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidvASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1543 KLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQK 1622
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 1834199290 1623 TAYLETKELRRQLESLELEKSREVLSLKAQMNGASSR 1659
Cdd:COG4913    752 EERFAAALGDAVERELRENLEERIDALRARLNRAEEE 788
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1272-1665 2.52e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 2.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1272 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESqtskEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1351
Cdd:pfam02463  144 IEIIAMMKPERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELI----IDLEELKLQELKLKEQAKKALEYYQLKEKL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1352 VRESSSIIEAQNTKLNESNvqlenktscLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKV 1431
Cdd:pfam02463  220 ELEEEYLLYLDYLKLNEER---------IDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKL 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1432 LEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNT 1511
Cdd:pfam02463  291 LAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1512 VLESQKKSHNEIQDKLEQAQ---QKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1588
Cdd:pfam02463  371 LEEELLAKKKLESERLSSAAklkEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEK 450

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1589 mddAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAqMNGASSRSGKGDE 1665
Cdd:pfam02463  451 ---EELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK-VLLALIKDGVGGR 523
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1147-1652 2.65e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.98  E-value: 2.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1147 LKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQttikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQ 1226
Cdd:pfam05557   14 LQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQ----ELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1227 VANANISATNAELSTVLEVLQAEKSETNHIFelfeMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQA 1306
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQI----QRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1307 QQSEQKLQQESQ--TSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEaQNTKLNESNVQLENKTSCLKETQ 1384
Cdd:pfam05557  166 AEAEQRIKELEFeiQSQEQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIE-NKLLLKEEVEDLKRKLEREEKYR 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQL----LESQKKEKQLQE-------------EAAKLSGELQQVQ-------EANGDIKDSLVKVEELVKVLEEKLQAAT 1440
Cdd:pfam05557  245 EEAatleLEKEKLEQELQSwvklaqdtglnlrSPEDLSRRIEQLQqreivlkEENSSLTSSARQLEKARRELEQELAQYL 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1441 SQLDAQQATNKELQELLVKSQE------NEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN---T 1511
Cdd:pfam05557  325 KKIEDLNKKLKRHKALVRRLQRrvllltKERDGYRAILESYDKELTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEaqlS 404

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1512 VLESQKKSHNEIQDKLEQAQQ--KERTLQEETSKLAEQLSQLKQANEELQkslQQKQLLLEKGNEFDTQLA--EYQKVID 1587
Cdd:pfam05557  405 VAEEELGGYKQQAQTLERELQalRQQESLADPSYSKEEVDSLRRKLETLE---LERQRLREQKNELEMELErrCLQGDYD 481

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1588 E------------MDDAASVKSALLEQLQNRV-----------AELETALRQANDAQKTAYLETKELRRQLESLEL--EK 1642
Cdd:pfam05557  482 PkktkvlhlsmnpAAEAYQQRKNQLEKLQAEIerlkrllkkleDDLEQVLRLPETTSTMNFKEVLDLRKELESAELknQR 561

                          570
                   ....*....|
gi 1834199290 1643 SREVLSLKAQ 1652
Cdd:pfam05557  562 LKEVFQAKIQ 571
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1151-1610 3.07e-08

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 58.94  E-value: 3.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1151 GERKE-KSFEESIKNLQEEVTKAKT-----------ENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKiadl 1218
Cdd:COG5022    807 GSRKEyRSYLACIIKLQKTIKREKKlreteevefslKAEVLIQKFGRSLKAKKRFSLLKKETIYLQSAQRVELAER---- 882

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1219 KTLVEAIQVANANISA-TNAEL-STVLEVLQAEKS----ETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1292
Cdd:COG5022    883 QLQELKIDVKSISSLKlVNLELeSEIIELKKSLSSdlieNLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEV 962

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1293 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESnvq 1372
Cdd:COG5022    963 ESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSES--- 1039

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1373 leNKTSCLKETQDQLLESQKKEKQLQEEAAKLsgelqQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKE 1452
Cdd:COG5022   1040 --TELSILKPLQKLKGLLLLENNQLQARYKAL-----KLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPA 1112

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1453 -LQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEAlcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQA- 1530
Cdd:COG5022   1113 nVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVL-------QLELDGLFWEANLEALPSPPPFAALSEKRLYQs 1185

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1531 ---QQKERTLQEETSKLAEQLSQL-KQANEELQKSLQQKQLLLEK--GNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQ 1604
Cdd:COG5022   1186 alyDEKSKLSSSEVNDLKNELIALfSKIFSGWPRGDKLKKLISEGwvPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLL 1265


                   ....*.
gi 1834199290 1605 NRVAEL 1610
Cdd:COG5022   1266 NSIDNL 1271
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1005-1627 3.51e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.77  E-value: 3.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1005 EEAKKSGHLLEQI-------TKLKSEVGETQAALSscHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 1077
Cdd:COG4913    245 EDAREQIELLEPIrelaeryAAARERLAELEYLRA--ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1078 DTLhAELQAERSSSsalhtklskfsdeiatGHKELtskaDAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS 1157
Cdd:COG4913    323 EEL-DELEAQIRGN----------------GGDRL----EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1158 FEESIKNLQEEVTKAKTE---NLELSTGTQTTIKDLQERLEITNAELQH---------------KEKMASEDAQKIADLK 1219
Cdd:COG4913    382 FAALRAEAAALLEALEEEleaLEEALAEAEAALRDLRRELRELEAEIASlerrksniparllalRDALAEALGLDEAELP 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1220 TLVEAIQVANANISATNA-E----------------LSTVLEVLQAEKSETNHIFELFE--------MEADMNSerLIEK 1274
Cdd:COG4913    462 FVGELIEVRPEEERWRGAiErvlggfaltllvppehYAAALRWVNRLHLRGRLVYERVRtglpdperPRLDPDS--LAGK 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1275 VTgIK------------------------EELKE---------------THLQLDERQKKFEEL------EEKLKQAQQS 1309
Cdd:COG4913    540 LD-FKphpfrawleaelgrrfdyvcvdspEELRRhpraitragqvkgngTRHEKDDRRRIRSRYvlgfdnRAKLAALEAE 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1310 EQKLQQESQTSKEKLTEIQQSLQELQdsvkQKEELVQNLEEKVRESSSIIEAQnTKLNESNVQLENktscLKETQDQLLE 1389
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQ----ERREALQRLAEYSWDEIDVASAE-REIAELEAELER----LDASSDDLAA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1390 SQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATN--KELQELLVKSQENE--G 1465
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALleERFAAALGDAVERElrE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1466 NLQGESLAVTEKLQQLEQANGELKEALCQK-ENGLKELQGKLDEsntvLESQKKSHNEIQ-DKLEQAQQKERTLQEETS- 1542
Cdd:COG4913    770 NLEERIDALRARLNRAEEELERAMRAFNREwPAETADLDADLES----LPEYLALLDRLEeDGLPEYEERFKELLNENSi 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1543 -KLAEQLSQLKQANEE-------LQKSLQQKQ------LLLEKGNEFDTQLAEYQKVIDEMDDAASVKSA-LLEQLQNRV 1607
Cdd:COG4913    846 eFVADLLSKLRRAIREikeridpLNDSLKRIPfgpgryLRLEARPRPDPEVREFRQELRAVTSGASLFDEeLSEARFAAL 925

                          730       740
                   ....*....|....*....|
gi 1834199290 1608 AELETALRQANDAQKTAYLE 1627
Cdd:COG4913    926 KRLIERLRSEEEESDRRWRA 945
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
842-1332 3.81e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 3.81e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  842 ALKQNELEDFQKKQSESEVHLQEIKAQNTQKDfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE-- 919
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQll 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  920 ---QELQQLQSKSAESESALKVVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKstqsnlEAKSKQL 996
Cdd:COG4717    129 plyQELEALEAELAELPERLEEL---------------EERLEELRELEEELEELEAELAELQEELE------ELLEQLS 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  997 EAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEAS--DLQDKVK 1074
Cdd:COG4717    188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-ERLKEARLLLLIAAAllALLGLGG 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1075 EITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAegerk 1154
Cdd:COG4717    267 SLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE----- 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1155 eksFEESIKNLQEEVTKAKTENLELstgtqttikdLQERLEITNAELQHKEKMASED-----AQKIADLKTLVEAIQVAN 1229
Cdd:COG4717    342 ---LLDRIEELQELLREAEELEEEL----------QLEELEQEIAALLAEAGVEDEEelraaLEQAEEYQELKEELEELE 408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1230 ANISATNAELSTVLEVLQAEKSETnhifELFEMEADMNS-----ERLIEKVTGIKEELK--ETHLQLDERQKKFEELEEK 1302
Cdd:COG4717    409 EQLEELLGELEELLEALDEEELEE----ELEELEEELEEleeelEELREELAELEAELEqlEEDGELAELLQELEELKAE 484

                          490       500       510
                   ....*....|....*....|....*....|
gi 1834199290 1303 LKQAQQSEQKLQQESQTSKEKLTEIQQSLQ 1332
Cdd:COG4717    485 LRELAEEWAALKLALELLEEAREEYREERL 514
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
774-1248 5.31e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 57.86  E-value: 5.31e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  774 KSTLLEKTEKELVQSKEQAAKTLNdKEQLEKQISDLKQLAEQEKLVREMTEN--AINQIQLEKESIEQQLALKQNELEDF 851
Cdd:COG4717     36 KSTLLAFIRAMLLERLEKEADELF-KPQGRKPELNLKELKELEEELKEAEEKeeEYAELQEELEELEEELEELEAELEEL 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  852 QKKQSESEVHLQeikaqntqkdfeLVESGESLKKLQQQLEQktlghekLQAALEELKkeketiikEKEQELQQLQSKSAE 931
Cdd:COG4717    115 REELEKLEKLLQ------------LLPLYQELEALEAELAE-------LPERLEELE--------ERLEELRELEEELEE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  932 SESALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsg 1011
Cdd:COG4717    168 LEAELAELQEELEELLEQLSLATEE---ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-- 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1012 hllEQITKLKS--EVGETQAALSSCHTDVESKTKQLEAANAAL----------EKVNKEYAESRAEASDLQDKVKEITDT 1079
Cdd:COG4717    243 ---ERLKEARLllLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallfllLAREKASLGKEAEELQALPALEELEEE 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1080 LHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQK--EKELQELRQQLQDSQDSQTKLKAEGERKEKS 1157
Cdd:COG4717    320 ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEelEQEIAALLAEAGVEDEEELRAALEQAEEYQE 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1158 FEESIKNLQEEVTKAKTENLELSTGTQTTikDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvANANISATNA 1237
Cdd:COG4717    400 LKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQ 476

                          490
                   ....*....|.
gi 1834199290 1238 ELSTVLEVLQA 1248
Cdd:COG4717    477 ELEELKAELRE 487
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1246-1616 9.17e-08

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 56.83  E-value: 9.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1246 LQAEKSETNHIFELFEMeADMNSERLIEKVTGIKEELKETHLQLDERqkkFEELEEKLKQAQQSEQKLQQESQTSKEKLT 1325
Cdd:pfam07888   36 LEECLQERAELLQAQEA-ANRQREKEKERYKRDREQWERQRRELESR---VAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1326 EIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLS 1405
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLS 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1406 GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKEL---QELLVKSQENEGNLqGESLAVTEKLQQLE 1482
Cdd:pfam07888  192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELrslQERLNASERKVEGL-GEELSSMAAQRDRT 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1483 QAngELKEALCQkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERtlqeetSKLAEQLSQLKQANEELQKSL 1562
Cdd:pfam07888  271 QA--ELHQARLQ----AAQLTLQLADASLALREGRARWAQERETLQQSAEADK------DRIEKLSAELQRLEERLQEER 338

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1563 QQKQLL-LEKGNEFD---TQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQ 1616
Cdd:pfam07888  339 MEREKLeVELGREKDcnrVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQ 396
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1112-1370 1.23e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 1.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1112 LTSKADAWSQEMLQKEKELQELRQQLQDSQdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQ 1191
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELE----KELAALKKEEKALLKQLAALERRIAALARRIRAL----EQELAALE 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1192 ERLEITNAELQHKEKmaSEDAQKiADLKTLVEAIQvananisaTNAELSTVLEVLQAEKSetNHIFELFEMEADMNSERl 1271
Cdd:COG4942     83 AELAELEKEIAELRA--ELEAQK-EELAELLRALY--------RLGRQPPLALLLSPEDF--LDAVRRLQYLKYLAPAR- 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1272 IEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEK 1351
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228

                          250
                   ....*....|....*....
gi 1834199290 1352 VRESSSIIEAQNTKLNESN 1370
Cdd:COG4942    229 IARLEAEAAAAAERTPAAG 247
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1259-1589 1.42e-07

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 56.40  E-value: 1.42e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1259 LFEMEADMNSERLIEkvtgIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQE----L 1334
Cdd:pfam06160   69 LFEAEELNDKYRFKK----AKKALDEIEELLDDIEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLAnrfsY 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1335 QDSVKQKEELVQNLEEK------VRESSSIIEAQNT--KLNESNVQLENKTS--------CLKETQDQLLESQKKEKQLQ 1398
Cdd:pfam06160  145 GPAIDELEKQLAEIEEEfsqfeeLTESGDYLEAREVleKLEEETDALEELMEdipplyeeLKTELPDQLEELKEGYREME 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1399 E-----EAAKLSGELQQVQEangDIKDSLVKVEEL-VKVLEEKLQAATSQLDAqqatnkeLQELLVKSQENEGNLQGESL 1472
Cdd:pfam06160  225 EegyalEHLNVDKEIQQLEE---QLEENLALLENLeLDEAEEALEEIEERIDQ-------LYDLLEKEVDAKKYVEKNLP 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1473 AVTEKLQQLEQANGELKE--ALCQKENGL--KELQgKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL 1548
Cdd:pfam06160  295 EIEDYLEHAEEQNKELKEelERVQQSYTLneNELE-RVRGLEKQLEELEKRYDEIVERLEEKEVAYSELQEELEEILEQL 373

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1834199290 1549 SQLKQANEELQKSLQQkqllLEKGnEFDTQ--LAEYQKVIDEM 1589
Cdd:pfam06160  374 EEIEEEQEEFKESLQS----LRKD-ELEARekLDEFKLELREI 411
PRK11281 PRK11281
mechanosensitive channel MscK;
1381-1624 1.48e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 56.84  E-value: 1.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1381 KETQDQLlESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKElqell 1457
Cdd:PRK11281    39 ADVQAQL-DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAqapAKLRQAQAELEALKDDNDE----- 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1458 VKSQENEgnlqgeslavTEKLQQLEQangelkeALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKertL 1537
Cdd:PRK11281   113 ETRETLS----------TLSLRQLES-------RLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQR---L 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1538 QEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAE--------YQKVIDEMddaaSVKSALLEQ----LQN 1605
Cdd:PRK11281   173 QQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEgntqlqdlLQKQRDYL----TARIQRLEHqlqlLQE 248

                          250       260
                   ....*....|....*....|....
gi 1834199290 1606 -----RVAELETALRQANDAQKTA 1624
Cdd:PRK11281   249 ainskRLTLSEKTVQEAQSQDEAA 272
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 958-1182 1.91e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 1.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  958 SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTD 1037
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1038 VESKTKQLEAANAALEKVNKEY-------AESRAEASDLQDKVKEITDTLHA---ELQAERSSSSALHTKLSKFSDEIAT 1107
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPplalllsPEDFLDAVRRLQYLKYLAPARREqaeELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1108 GHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTG 1182
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1128-1575 1.94e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 1.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1128 KELQELRQQLQDSQDSQTKLKAEGERKEKSfEESIKNLQEEVTKAKTENLELSTGTQttIKDLQERLEITNAELQHKEKM 1207
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEEL-EEELEELEAELEELREELEKLEKLLQ--LLPLYQELEALEAELAELPER 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1208 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemeadmnSERLIEKVTGIKEELKETHL 1287
Cdd:COG4717    148 LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE--------------LQDLAEELEELQQRLAELEE 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1288 QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQS-LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKL 1366
Cdd:COG4717    214 ELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1367 NESNVQLENKT------SCLKETQDQLLESQKKEKQLQ-----EEAAKLSGELQQVQEANGDIKD-----SLVKVEELVK 1430
Cdd:COG4717    294 AREKASLGKEAeelqalPALEELEEEELEELLAALGLPpdlspEELLELLDRIEELQELLREAEEleeelQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1431 VL--------EEKLQAATSQLDAQQATNKELQELlvKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKEL 1502
Cdd:COG4717    374 ALlaeagvedEEELRAALEQAEEYQELKEELEEL--EEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290 1503 QGKLDESNTVLESQKKShneiqDKLEQAQQKERTLQEETSKLAEQ---LSQLKQANEELQKSLQQKQL--LLEKGNEF 1575
Cdd:COG4717    452 REELAELEAELEQLEED-----GELAELLQELEELKAELRELAEEwaaLKLALELLEEAREEYREERLppVLERASEY 524
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 766-1561 2.53e-07

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 55.99  E-value: 2.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  766 LQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLaeqeklvremtENAINQIQLEKESIEQQLALKQ 845
Cdd:PTZ00440   839 LQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENMNKNINIIKTL-----------NIAINRSNSNKQLVEHLLNNKI 907

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  846 NELEDFQKkqsesevHLQEIKAQN----TQKDFELVESGESLKKLQQQLEQKTLGHEKLQA--ALEELKKEKETIIKEKE 919
Cdd:PTZ00440   908 DLKNKLEQ-------HMKIINTDNiiqkNEKLNLLNNLNKEKEKIEKQLSDTKINNLKMQIekTLEYYDKSKENINGNDG 980

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  920 QELQQLQSKSAESEsALKVVQVQLEQLQQQAAASGEEgskTVAKLHDEISQLksqaeeTQSELKSTQSNLEAKSKQLEAa 999
Cdd:PTZ00440   981 THLEKLDKEKDEWE-HFKSEIDKLNVNYNILNKKIDD---LIKKQHDDIIEL------IDKLIKEKGKEIEEKVDQYIS- 1049

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1000 ngSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEItdt 1079
Cdd:PTZ00440  1050 --LLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLIEIKNKSHEHVVNADKEKNKQTEH--- 1124

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1080 lhaeLQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFE 1159
Cdd:PTZ00440  1125 ----YNKKKKSLEKIYKQMEKTLKELENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKSKTIMEEIESYKKDID 1200

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1160 ESIKNLQEEvTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKmaSEDAQKIADLKT--------LVEAIQVANAn 1231
Cdd:PTZ00440  1201 QVKKNMSKE-RNDHLTTFEYNAYYDKATASYENIEELTTEAKGLKGE--ANRSTNVDELKEiklqvfsyLQQVIKENNK- 1276

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1232 ISATNAELSTVLEVLQAEKSET------NHIFELFEMEADMNSErlIEKVTGIKEELKETHLQLDERQKKFEELEEKlKQ 1305
Cdd:PTZ00440  1277 MENALHEIKNMYEFLISIDSEKilkeilNSTKKAEEFSNDAKKE--LEKTDNLIKQVEAKIEQAKEHKNKIYGSLED-KQ 1353

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1306 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE-KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQ 1384
Cdd:PTZ00440  1354 IDDEIKKIEQIKEEISNKRKEINKYLSNIKSNKEKCDLHVRNASRgKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK 1433

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQLLESQKKEKQLQEEAAKLsgeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENE 1464
Cdd:PTZ00440  1434 QYSNEAMETENKADENNDSI---IKYEKEITNILNNSSILGKK--TKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKL 1508

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1465 GNLQ--------GESLA---VTEKLQQLEQANGELKEALCQKENGLKELQ----------------GKLDESNTvLESQK 1517
Cdd:PTZ00440  1509 NQLNeqpnikreGDVLNndkSTIAYETIQYNLGRVKHNLLNILNIKDEIEtilnkaqdlmrdiskiSKIVENKN-LENLN 1587

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1834199290 1518 KSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKS 1561
Cdd:PTZ00440  1588 DKEADYVKYLDNILKEKQLMEAEYKKLNEIYSDVDNIEKELKKH 1631
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 592-875 2.66e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.51  E-value: 2.66e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  592 QEEIAKLQEKMTIQQKevesRIAEQLEEEQRLRENVKYLNEQIATLqselVSKDEALEKFSLSECGIENLRRELELLKEE 671
Cdd:pfam17380  332 QAAIYAEQERMAMERE----RELERIRQEERKRELERIRQEEIAME----ISRMRELERLQMERQQKNERVRQELEAARK 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  672 NEKQAQEAQaeftRKLAEKSVEVLRLSSELQNLKATS-DSLESERVNktdECEILQTEVRMRDEQIRELNQQLDEvttql 750
Cdd:pfam17380  404 VKILEEERQ----RKIQQQKVEMEQIRAEQEEARQREvRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEE----- 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  751 nvQKADSSALDDMLRLQKEGTEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI 830
Cdd:pfam17380  472 --RKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1834199290  831 QL-EKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFE 875
Cdd:pfam17380  547 EMeERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1280-1567 3.58e-07

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 53.76  E-value: 3.58e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1280 EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1359
Cdd:COG1340      1 SKTDELSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEER 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1360 EAQNTKLNESNVQLENktscLKETQDQLLESQKKEKQLQEEAAKLSGElQQVQEANGDIKDSLVkveELVKVLEEKLQAA 1439
Cdd:COG1340     81 DELNEKLNELREELDE----LRKELAELNKAGGSIDKLRKEIERLEWR-QQTEVLSPEEEKELV---EKIKELEKELEKA 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1440 TSQLDAqqatNKELQELLvksqenegnlqGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKS 1519
Cdd:COG1340    153 KKALEK----NEKLKELR-----------AELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKE 217

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1834199290 1520 HNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQL 1567
Cdd:COG1340    218 IVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKREKEKEEL 265
PRK12704 PRK12704
phosphodiesterase; Provisional
 1245-1404 4.18e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 54.78  E-value: 4.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1245 VLQAEKsETNHIFELFEMEADMNSErliEKVTGIKEELK----ETHLQLDERQKKFEELEEKLkqaQQSEQKLQQESqts 1320
Cdd:PRK12704    33 IKEAEE-EAKRILEEAKKEAEAIKK---EALLEAKEEIHklrnEFEKELRERRNELQKLEKRL---LQKEENLDRKL--- 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1321 kEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssIIEAQNTKLNE-SNVQLEnktsclkETQDQLLESQKKEkqLQE 1399
Cdd:PRK12704   103 -ELLEKREEELEKKEKELEQKQQELEKKEEELEE---LIEEQLQELERiSGLTAE-------EAKEILLEKVEEE--ARH 169


                   ....*
gi 1834199290 1400 EAAKL 1404
Cdd:PRK12704   170 EAAVL 174
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
507-1026 4.44e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 4.44e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  507 KKKLFPLKARIVELESALDNERKKTEELQ------CSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSIL 580
Cdd:PRK03918   251 EGSKRKLEEKIRELEERIEELKKEIEELEekvkelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  581 ppdlpSDDGALQEEIAKLQEKMtiqqKEVESRIAEqLEEEQRLRENVKYLNEQIATLQSELvsKDEALEKFslsecgien 660
Cdd:PRK03918   331 -----KELEEKEERLEELKKKL----KELEKRLEE-LEERHELYEEAKAKKEELERLKKRL--TGLTPEKL--------- 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  661 lrrelellkEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERvnktDECEILQTEvrMRDEQIRELn 740
Cdd:PRK03918   390 ---------EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAK----GKCPVCGRE--LTEEHRKEL- 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  741 qqLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKtEKELVQSKEQAAKTLNDKEQLEKQisDLKQLAEQEKLVR 820
Cdd:PRK03918   454 --LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKLKKY--NLEELEKKAEEYE 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  821 EMTENAIN---QIQLEKESIEQQLALKqNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGES-LKKLQ----QQLEQ 892
Cdd:PRK03918   529 KLKEKLIKlkgEIKSLKKELEKLEELK-KKLAELEKKLDELEEELAELLKELEELGFESVEELEErLKELEpfynEYLEL 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  893 KTLGHEkLQAALEELKKEKETiIKEKEQELQQLQSKSAESESALKVVQVQ-LEQLQQQAAASGEEGSKTVAKLHDEISQL 971
Cdd:PRK03918   608 KDAEKE-LEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRAELEEL 685

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  972 KSQAEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLKSEVGE 1026
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKKELE-KLEKALERVEELREKVKKYKALLKE 739
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 583-1377 4.61e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.05  E-value: 4.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  583 DLPSDDGALQEEIAKLQEKMTIQQKEVESRiAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKfslsecgienlr 662
Cdd:TIGR00606  416 DLQSKERLKQEQADEIRDEKKGLGRTIELK-KEILEKKQEELKFVIKELQQLEGSSDRILELDQELRK------------ 482

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  663 relellkeenekqaqeaqaeftrklAEKSVEVLRLSSELQNLKATSDSLESERVNktdeceiLQTEVRMRDEQIRELNQQ 742
Cdd:TIGR00606  483 -------------------------AERELSKAEKNSLTETLKKEVKSLQNEKAD-------LDRKLRKLDQEMEQLNHH 530

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  743 LDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKtekelVQSKEQAAKTLNDKEQLEKQisdlkqlaeqeklvrem 822
Cdd:TIGR00606  531 TTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGY-----FPNKKQLEDWLHSKSKEINQ----------------- 588

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  823 TENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIkaqntqkdfelvesgeslkklqqqleqktLGHEKLQA 902
Cdd:TIGR00606  589 TRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDV-----------------------------CGSQDEES 639

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  903 ALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAaasgEEGSKTVAKLHDEISQLKSQAEETQSEL 982
Cdd:TIGR00606  640 DLERLKEE----IEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVC----QRVFQTEAELQEFISDLQSKLRLAPDKL 711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  983 KSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAES 1062
Cdd:TIGR00606  712 KSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE-EESAKVCLTD 790

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1063 RAEASDLQDKVKEITDTLhaELQAERSSSSALHTKLSKFSDEIATGHKEL---TSKADAWSQEMLQKEKELQELRQQLQD 1139
Cdd:TIGR00606  791 VTIMERFQMELKDVERKI--AQQAAKLQGSDLDRTVQQVNQEKQEKQHELdtvVSKIELNRKLIQDQQEQIQHLKSKTNE 868

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1140 SQDSQTKLKAEGERK---EKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEK-------MAS 1209
Cdd:TIGR00606  869 LKSEKLQIGTNLQRRqqfEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKaqdkvndIKE 948

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1210 EDAQKIADLKTLVEAIQVANAN-ISATNAELSTVLEVLQAEKSETNHIfelfemEADMNSERLIEKVTGIKEELKETHLQ 1288
Cdd:TIGR00606  949 KVKNIHGYMKDIENKIQDGKDDyLKQKETELNTVNAQLEECEKHQEKI------NEDMRLMRQDIDTQKIQERWLQDNLT 1022

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1289 LDERQKKFEELEEKLK------------QAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQ-----KEELVQNLEEK 1351
Cdd:TIGR00606 1023 LRKRENELKEVEEELKqhlkemgqmqvlQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHfkkelREPQFRDAEEK 1102

                          810       820
                   ....*....|....*....|....*.
gi 1834199290 1352 VREssSIIEAQNTKLNESNVQLENKT 1377
Cdd:TIGR00606 1103 YRE--MMIVMRTTELVNKDLDIYYKT 1126
PRK12704 PRK12704
phosphodiesterase; Provisional
 799-931 5.45e-07

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 54.40  E-value: 5.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  799 KEQLEKQISDLKQLAEQeklvremtenAINQIQLEKESIEQQLALKQNELEDFQKKQSESEV-----HLQEIKAQNTQKD 873
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKR----------ILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELrerrnELQKLEKRLLQKE 95

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1834199290  874 FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 931
Cdd:PRK12704    96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
46 PHA02562
endonuclease subunit; Provisional
 1211-1427 7.12e-07

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 54.25  E-value: 7.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1211 DAQKIADLKTLVEA-IQVANANISATNAELSTVLEVLqaeKSETNHIFELfEMEADMNSERLIEKVTGIKEELKETHLQL 1289
Cdd:PHA02562   161 DISVLSEMDKLNKDkIRELNQQIQTLDMKIDHIQQQI---KTYNKNIEEQ-RKKNGENIARKQNKYDELVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1290 DERQKKFEELEE----------KLKQAQ-------QSEQKL--------------QQESQTsKEKLTEIQQSLQELQDSV 1338
Cdd:PHA02562   237 EELTDELLNLVMdiedpsaalnKLNTAAakikskiEQFQKVikmyekggvcptctQQISEG-PDRITKIKDKLKELQHSL 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1339 KQKEELVQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI 1418
Cdd:PHA02562   316 EKLDTAIDELEEIMDE----FNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKI 391


                   ....*....
gi 1834199290 1419 KDSLVKVEE 1427
Cdd:PHA02562   392 VKTKSELVK 400
46 PHA02562
endonuclease subunit; Provisional
 808-1080 7.12e-07

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 54.25  E-value: 7.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  808 DLKQLAEQEKL----VREMTENaINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAqntqkdfELVESGESL 883
Cdd:PHA02562   161 DISVLSEMDKLnkdkIRELNQQ-IQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYD-------ELVEEAKTI 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  884 KklqQQLEQktlghekLQAALEELKKEKEtiikEKEQELQQLQSKSAESESALKvvqvqleqlqqqaaasgeegskTVAK 963
Cdd:PHA02562   233 K---AEIEE-------LTDELLNLVMDIE----DPSAALNKLNTAAAKIKSKIE----------------------QFQK 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  964 L------HDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKsevgETQAALSSCHTD 1037
Cdd:PHA02562   277 VikmyekGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLL----ELKNKISTNKQS 352

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1834199290 1038 VESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTL 1080
Cdd:PHA02562   353 LITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTK 395
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1288-1610 7.30e-07

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 54.29  E-value: 7.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1288 QLDERQkkfeeLEEKLKQAQQSEQKLQQES----QTSKEKLTEIQQSL---QELQDSVKQKEELVQNLEEKVRESSSiiE 1360
Cdd:PRK10929    22 APDEKQ-----ITQELEQAKAAKTPAQAEIvealQSALNWLEERKGSLeraKQYQQVIDNFPKLSAELRQQLNNERD--E 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1361 AQNTKLNESNVQLENKtscLKETQDQLLEsqkkekqlqeeaakLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAAT 1440
Cdd:PRK10929    95 PRSVPPNMSTDALEQE---ILQVSSQLLE--------------KSRQAQQEQDRAREISDSLSQLPQQQTEARRQLNEIE 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1441 SQLDAQQATNKELQELLVKSqenegnLQGESLAVTEKLQQLE---------QANGELKEALCQKENglKELQGKLDESNT 1511
Cdd:PRK10929   158 RRLQTLGTPNTPLAQAQLTA------LQAESAALKALVDELElaqlsannrQELARLRSELAKKRS--QQLDAYLQALRN 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1512 VLESQKkshneiQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSL-QQKQLLLEKGNEFDTQLAEYQKV----- 1585
Cdd:PRK10929   230 QLNSQR------QREAERALESTELLAEQSGDLPKSIVAQFKINRELSQALnQQAQRMDLIASQQRQAASQTLQVrqaln 303

                          330       340
                   ....*....|....*....|....*.
gi 1834199290 1586 -IDEMDDAASVKSALLEQLQNRVAEL 1610
Cdd:PRK10929   304 tLREQSQWLGVSNALGEALRAQVARL 329
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 518-1541 7.48e-07

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 54.45  E-value: 7.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  518 VELESALDNERKKTEELQCSIDEAQFCGDELNAQSQ---VYKEKIHDLESKITKLVSATP-SLQSILppDLPSDDGA--- 590
Cdd:PTZ00440   487 EKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKnieDYYITIEGLKNEIEGLIELIKyYLQSIE--TLIKDEKLkrs 564

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  591 LQEEIAK-----------------LQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSL 653
Cdd:PTZ00440   565 MKNDIKNkikyieenvdhikdiisLNDEIDNIIQQIEELINEALFNKEKFINEKNDLQEKVKYILNKFYKGDLQELLDEL 644

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  654 SECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVL-----RLSSELQNLKATSDSLESERVNKtdeceiLQTE 728
Cdd:PTZ00440   645 SHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMKSDNIdniikNLKKELQNLLSLKENIIKKQLNN------IEQD 718

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  729 VRMRDEQIRElnqQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQL---EKQ 805
Cdd:PTZ00440   719 ISNSLNQYTI---KYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDLPDGKNTYEEFLQYKDTIlnkENK 795

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  806 IS-DLKQLAEQEKLVREMTENAINQIQLEK-------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELV 877
Cdd:PTZ00440   796 ISnDINILKENKKNNQDLLNSYNILIQKLEahtekndEELKQLLQKFPTEDENLNLKELEKEFNENNQIVDNIIKDIENM 875

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  878 ESG-ESLKKLQQQLEqktlGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqLQQQAAASGEE 956
Cdd:PTZ00440   876 NKNiNIIKTLNIAIN----RSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNE----------KLNLLNNLNKE 941

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  957 GSKTVAKLHDE-ISQLKSQAEETQSELKSTQSNLEAKSK-QLEaangSLEEEAKKSGHLLEQITKLKSEVGETQAALSSc 1034
Cdd:PTZ00440   942 KEKIEKQLSDTkINNLKMQIEKTLEYYDKSKENINGNDGtHLE----KLDKEKDEWEHFKSEIDKLNVNYNILNKKIDD- 1016

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1035 hTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTS 1114
Cdd:PTZ00440  1017 -LIKKQHDDIIELIDKLIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDE 1095

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1115 KADAWSQEMLQKEKELQELRQQLQdsqdsqtKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTqttikdlqerl 1194
Cdd:PTZ00440  1096 NKNKLIEIKNKSHEHVVNADKEKN-------KQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN----------- 1157

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1195 EITNAELQHKEKMASEDAQKIAD-----------LKTLVEAIQVANANISATNAELSTVLEVLQAEKSETnhifelfemE 1263
Cdd:PTZ00440  1158 EVNEIEIEYERILIDHIVEQINNeakksktimeeIESYKKDIDQVKKNMSKERNDHLTTFEYNAYYDKAT---------A 1228

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1264 ADMNSERLIEKVTGIKEElkethlqlDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQ------------QSL 1331
Cdd:PTZ00440  1229 SYENIEELTTEAKGLKGE--------ANRSTNVDELKEIKLQVFSYLQQVIKENNKMENALHEIKnmyeflisidseKIL 1300

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1332 QELQDSVKQKEELVQNLEEKVRESSSIIEaqntklnesnvQLENKTSCLKETQDQLLESQkKEKQLQEEAAKLSGELQQV 1411
Cdd:PTZ00440  1301 KEILNSTKKAEEFSNDAKKELEKTDNLIK-----------QVEAKIEQAKEHKNKIYGSL-EDKQIDDEIKKIEQIKEEI 1368

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1412 QEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEklQQLEQANGELKEA 1491
Cdd:PTZ00440  1369 SNKRKEINKYLSNIKSNKEKCDLHVRNASRGKDKIDFLNKHEAIEPSNSKEVNIIKITDNINKCK--QYSNEAMETENKA 1446

                         1050      1060      1070      1080      1090      1100
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1492 LCQKENGLK-------------------ELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEET 1541
Cdd:PTZ00440  1447 DENNDSIIKyekeitnilnnssilgkktKLEKKKKEATNIMDDINGEHSIIKTKLTKSSEKLNQLNEQP 1515
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
613-860 7.90e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.25  E-value: 7.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  613 IAEQLEEEQ-RLRENVKYLNEQIATLQSELVSKDEALEKFsLSECGIENlrrelellkeenekqAQEAQAEFTRKLAEKS 691
Cdd:COG3206    162 LEQNLELRReEARKALEFLEEQLPELRKELEEAEAALEEF-RQKNGLVD---------------LSEEAKLLLQQLSELE 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  692 VEVLRLSSELQNLKATSDSLESERVNKTDECEILQTevrmrDEQIRELNQQLDEVTTQLNVQKADSSALD-DMLRLQKEg 770
Cdd:COG3206    226 SQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNHpDVIALRAQ- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  771 teekstlLEKTEKELVQSKEQAAKTL-NDKEQLEKQISDL-KQLAEQEKLVREMtenaiNQIQLEKESIEQQLALKQNEL 848
Cdd:COG3206    300 -------IAALRAQLQQEAQRILASLeAELEALQAREASLqAQLAQLEARLAEL-----PELEAELRRLEREVEVARELY 367

                          250
                   ....*....|..
gi 1834199290  849 EDFQKKQSESEV 860
Cdd:COG3206    368 ESLLQRLEEARL 379
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1299-1534 8.46e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.87  E-value: 8.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1299 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELqdsvKQKEELVqNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1378
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLV-DLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1379 CLKETQDQLLESQKKEKQLQEEAAkLSGELQQVQEANGDIKDSLVKVEE---LVKVLEEKLQAATSQLDAqqatnkELQE 1455
Cdd:COG3206    241 RLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPnhpDVIALRAQIAALRAQLQQ------EAQR 313

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1456 LLVksqenegNLQGESLAVTEKLQQLEQANGELKEALcqkeNGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKE 1534
Cdd:COG3206    314 ILA-------SLEAELEALQAREASLQAQLAQLEARL----AELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 973-1199 8.83e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 8.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  973 SQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAL 1052
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1053 EKVNKEYAEsRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 1132
Cdd:COG4942    100 EAQKEELAE-LLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1133 LRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNA 1199
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1380-1625 9.46e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 53.30  E-value: 9.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1380 LKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQAtnkELQELLVK 1459
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1460 SQENEGNLQgeslavteKLQQLEQANGelkealcqkengLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE 1539
Cdd:COG3883     95 LYRSGGSVS--------YLDVLLGSES------------FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEA 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1540 ETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAND 1619
Cdd:COG3883    155 KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234


                   ....*.
gi 1834199290 1620 AQKTAY 1625
Cdd:COG3883    235 AAAAAA 240
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 865-1501 1.01e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 53.96  E-value: 1.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  865 IKAQNTQKD--FELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQ 942
Cdd:pfam05483  204 VQAENARLEmhFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDEN 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  943 LEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSleeeakKSGHLLeQITKLKS 1022
Cdd:pfam05483  284 LKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKA------KAAHSF-VVTEFEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1023 EVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLhaelqAERSSSSALHTKLSKFS 1102
Cdd:pfam05483  357 TTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKIL-----AEDEKLLDEKKQFEKIA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1103 DEIATGHKELTSKADAwsqemlqKEKELQELRQQLQDSQDSqtklkaegerkEKSFEESIKNLQEEVTKAKTENLELSTG 1182
Cdd:pfam05483  432 EELKGKEQELIFLLQA-------REKEIHDLEIQLTAIKTS-----------EEHYLKEVEDLKTELEKEKLKNIELTAH 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1183 tqttikdlqerleiTNAELQHKEKMASEDAQKIADLKTLVEAIqvananISATNAELSTVLEVLQAEKSETNhifelFEM 1262
Cdd:pfam05483  494 --------------CDKLLLENKELTQEASDMTLELKKHQEDI------INCKKQEERMLKQIENLEEKEMN-----LRD 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1263 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1342
Cdd:pfam05483  549 ELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAEN 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1343 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQqvQEANGDIKDSL 1422
Cdd:pfam05483  629 KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID--KRCQHKIAEMV 706

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1423 VKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE 1501
Cdd:pfam05483  707 ALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 569-817 1.21e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 1.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  569 LVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMtiqqKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEAL 648
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  649 EKFSLSEcgienlrrelellkeeneKQAQEAQAEFTRKLAEKSVEVLRLS--SELQNLKATSDSLESERVNktdecEILQ 726
Cdd:COG4942     86 AELEKEI------------------AELRAELEAQKEELAELLRALYRLGrqPPLALLLSPEDFLDAVRRL-----QYLK 142

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  727 TEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKE-------GTEEKSTLLEKTEKELVQSKEQAAKTLNDK 799
Cdd:COG4942    143 YLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEeraaleaLKAERQKLLARLEKELAELAAELAELQQEA 222

                          250
                   ....*....|....*...
gi 1834199290  800 EQLEKQISDLKQLAEQEK 817
Cdd:COG4942    223 EELEALIARLEAEAAAAA 240
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1773-1789 1.39e-06

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 45.92  E-value: 1.39e-06
                           10
                   ....*....|....*..
gi 1834199290 1773 RKYCDSCEVFGHDTSEC 1789
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1175-1656 1.39e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.69  E-value: 1.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1175 ENLELSTGTQ-TTIKDLQERLEITNAE--LQHKEKMASEDAQKIADLKTlVEAIQVANA--------NISATNAELSTVL 1243
Cdd:pfam12128  149 QNDRTLLGRErVELRSLARQFALCDSEspLRHIDKIAKAMHSKEGKFRD-VKSMIVAILeddgvvppKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1244 EVLQAEKSETNHIFELFEMEADMNS-ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQaqqseqKLQQESQTSKE 1322
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTlESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQ------LLRTLDDQWKE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1323 KLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQDQLLESQ---------K 1392
Cdd:pfam12128  302 KRDELNGELSAADAAVAKDRSELEALEDQHGAFLDA-DIETAAADQEQLpSWQSELENLEERLKALTGKHqdvtakynrR 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1393 KEKQLQEEAAKLSGeLQQVQEANGDIKDSLVKVEElvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESL 1472
Cdd:pfam12128  381 RSKIKEQNNRDIAG-IKDKLAKIREARDRQLAVAE--DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQAT 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1473 AVTEKLQQLEQANGEL---KEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQL- 1548
Cdd:pfam12128  458 ATPELLLQLENFDERIeraREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLl 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1549 ----SQLKQANEELQKSLQQKQLLlekgnefDTQLaeyqkviDEMDDAASVKSAL--------LEQLQ-NRVAELETALR 1615
Cdd:pfam12128  538 hflrKEAPDWEQSIGKVISPELLH-------RTDL-------DPEVWDGSVGGELnlygvkldLKRIDvPEWAASEEELR 603

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1834199290 1616 QANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGA 1656
Cdd:pfam12128  604 ERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
PRK11281 PRK11281
mechanosensitive channel MscK;
519-929 1.41e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  519 ELESALD--NERKKTEE----LQCSIDEAQfcgdELNAQSQVYKEKIHDLESKITKlvsATPSLQSIlppdlpsddgalQ 592
Cdd:PRK11281    40 DVQAQLDalNKQKLLEAedklVQQDLEQTL----ALLDKIDRQKEETEQLKQQLAQ---APAKLRQA------------Q 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKM---------TIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSelvskdealekfslsecgienlrr 663
Cdd:PRK11281   101 AELEALKDDNdeetretlsTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT------------------------ 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  664 elellkeenekQAQEAQAEftrkLAEKSVEVLRLSSELQNLKATSDSLESERVNKtdeceiLQTEVRMRDEQIrELNQQL 743
Cdd:PRK11281   157 -----------QPERAQAA----LYANSQRLQQIRNLLKGGKVGGKALRPSQRVL------LQAEQALLNAQN-DLQRKS 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  744 DEVTTQLNvqkadssaldDMLRLQKEGTEEKSTLLEKT---------EKELVQSKEQAAKTLNDKE------------QL 802
Cdd:PRK11281   215 LEGNTQLQ----------DLLQKQRDYLTARIQRLEHQlqllqeainSKRLTLSEKTVQEAQSQDEaariqanplvaqEL 284

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  803 E--KQISD--------LKQLAEQEKLVREMTENAINQIQLEKESI--------------EQQLALKQNEL-EDFQKKQSE 857
Cdd:PRK11281   285 EinLQLSQrllkatekLNTLTQQNLRVKNWLDRLTQSERNIKEQIsvlkgslllsrilyQQQQALPSADLiEGLADRIAD 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  858 SEVHLQEIkaqNTQKDfELVESGESLKKLQQQleQKTLGHEKLQAALEELKKEKETIIKEKEQEL--------------Q 923
Cdd:PRK11281   365 LRLEQFEI---NQQRD-ALFQPDAYIDKLEAG--HKSEVTDEVRDALLQLLDERRELLDQLNKQLnnqlnlainlqlnqQ 438


                   ....*.
gi 1834199290  924 QLQSKS 929
Cdd:PRK11281   439 QLLSVS 444
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
764-1195 1.41e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  764 LRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKEsiEQQLAL 843
Cdd:COG4717     83 AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEER--LEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  844 KQNELEDFQKKQSESEVHLQEIKAQNT-QKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKE--Q 920
Cdd:COG4717    161 LEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaaA 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  921 ELQQLQSK--SAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEA 998
Cdd:COG4717    241 LEERLKEArlLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEE 320

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  999 ANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVES-KTKQLEAANAALEK----VNKEYAESRAEASDLQDKV 1073
Cdd:COG4717    321 LEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELEQEIAALLAeagvEDEEELRAALEQAEEYQEL 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1074 KEITDTLHAELQAERSSSSALHTKLSKfsDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGER 1153
Cdd:COG4717    401 KEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL 478

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1154 KEKsfEESIKNLQEEVTKAKTenlelstgTQTTIKDLQERLE 1195
Cdd:COG4717    479 EEL--KAELRELAEEWAALKL--------ALELLEEAREEYR 510
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1382-1550 1.64e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1382 ETQDQLLESQKKEKQLQE---EAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELL- 1457
Cdd:COG1579      4 EDLRALLDLQELDSELDRlehRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLg 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1458 -VKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKshnEIQDKLEQAQQKERT 1536
Cdd:COG1579     84 nVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKA---ELDEELAELEAELEE 160

                          170
                   ....*....|....
gi 1834199290 1537 LQEETSKLAEQLSQ 1550
Cdd:COG1579    161 LEAEREELAAKIPP 174
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 755-936 1.70e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 1.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  755 ADSSALDDMLRLQKEGTEekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEK 834
Cdd:COG1579      1 AMPEDLRALLDLQELDSE-----LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARI 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  835 ESIEQQLALKQN--ELEDFQKKqsesevhLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKE 912
Cdd:COG1579     76 KKYEEQLGNVRNnkEYEALQKE-------IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD 148

                          170       180
                   ....*....|....*....|....
gi 1834199290  913 TIIKEKEQELQQLQSKSAESESAL 936
Cdd:COG1579    149 EELAELEAELEELEAEREELAAKI 172
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 687-1023 1.76e-06

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 52.90  E-value: 1.76e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  687 LAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRL 766
Cdd:pfam10174  361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTT 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  767 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLndkEQLEKQISDLKQ--------LAEQEKLVREMTENAINQIQ--LEKES 836
Cdd:pfam10174  441 LEEALSEKERIIERLKEQREREDRERLEEL---ESLKKENKDLKEkvsalqpeLTEKESSLIDLKEHASSLASsgLKKDS 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  837 ieqqlALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFEL-VESGESLKKLQQQLEQKTLGHEKLQAALEEL-------- 907
Cdd:pfam10174  518 -----KLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTnPEINDRIRLLEQEVARYKEESGKAQAEVERLlgilreve 592

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  908 --KKEKETIIKE---------KEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAE 976
Cdd:pfam10174  593 neKNDKDKKIAElesltlrqmKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELD 672

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290  977 ETQSELKSTQSNLEAKSKQLEaangSLEEEAKKSghlLEQITKLKSE 1023
Cdd:pfam10174  673 ATKARLSSTQQSLAEKDGHLT----NLRAERRKQ---LEEILEMKQE 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 686-932 1.89e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 1.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  686 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLR 765
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  766 LQKEgteEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvREMTENAINQIQLEKESIEQQLALKQ 845
Cdd:COG4942    101 AQKE---ELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA----RREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  846 NELEDFQKKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQL 925
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKL----------LARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ....*..
gi 1834199290  926 QSKSAES 932
Cdd:COG4942    244 PAAGFAA 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1310-1566 2.12e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 52.71  E-value: 2.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1310 EQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLeekvRESSSIIEAQNtklnESNVQLENktscLKETQDQLLE 1389
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF----RQKNGLVDLSE----EAKLLLQQ----LSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1390 SQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkveELVKVLEEKLQAATSQLDAQQATNKElqellvksqenegnlqg 1469
Cdd:COG3206    231 ARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTP----------------- 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1470 ESLAVTEKLQQLEQANGELKEalcqkenglkELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEqLS 1549
Cdd:COG3206    289 NHPDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR-LE 357

                          250
                   ....*....|....*..
gi 1834199290 1550 QLKQANEELQKSLQQKQ 1566
Cdd:COG3206    358 REVEVARELYESLLQRL 374
PRK09039 PRK09039
peptidoglycan -binding protein;
724-863 2.13e-06

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 51.89  E-value: 2.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  724 ILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDML-RLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQL 802
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVaNLRAS--------LSAAEAERSRLQALLAELAGAGAAA 114

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290  803 EKQISDL-KQLAEQEKLvremTENAINQIQLEKESIEQ---QLALKQNELEDFQKKQSESEVHLQ 863
Cdd:PRK09039   115 EGRAGELaQELDSEKQV----SARALAQVELLNQQIAAlrrQLAALEAALDASEKRDRESQAKIA 175
CagA_N pfam18971
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...
 1346-1628 2.74e-06

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.


Pssm-ID: 408741 [Multi-domain]  Cd Length: 876  Bit Score: 52.47  E-value: 2.74e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1346 QNLEEKvresssiIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQlqeeaAKLSGELQQVQEANGDIKDSLVKV 1425
Cdd:pfam18971  559 RNLENK-------LTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAE-----AKSTGNYDEVKKAQKDLEKSLRKR 626

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1426 EELVKVLEEKLQAAT---SQLDAQQATNKELQEL--LVKSQENEG--------NLQGESLAVTEKLQQLEQANGELKEAL 1492
Cdd:pfam18971  627 EHLEKEVEKKLESKSgnkNKMEAKAQANSQKDEIfaLINKEANRDaraiaytqNLKGIKRELSDKLEKISKDLKDFSKSF 706

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1493 CQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLqqKQLLLEkg 1572
Cdd:pfam18971  707 DEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSV--KDVIIN-- 782

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1573 nefdtqlaeyQKVIDEMDD---AASVKSAL--LEQLQNRVAELETALRQ--ANDAQKTAYLET 1628
Cdd:pfam18971  783 ----------QKVTDKVDNlnqAVSVAKAMgdFSRVEQVLADLKNFSKEqlAQQAQKNEDFNT 835
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1287-1478 3.96e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 3.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1287 LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsiiEAQNTKL 1366
Cdd:COG1579     10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYE---EQLGNVR 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1367 NESNVQlenktSCLKEtqdqlLESQKKEKQLQEEaaklsgELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQ 1446
Cdd:COG1579     87 NNKEYE-----ALQKE-----IESLKRRISDLED------EILELMERIEELEEELAELEAELAELEAELEEKKAELDEE 150

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1834199290 1447 QA-TNKELQELLVKSQENEGNLQGESLAVTEKL 1478
Cdd:COG1579    151 LAeLEAELEELEAEREELAAKIPPELLALYERI 183
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 801-937 4.63e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.92  E-value: 4.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  801 QLEKQISDL-KQLAEQEKLVREMtENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKaqnTQKDFELVES 879
Cdd:COG1579     21 RLEHRLKELpAELAELEDELAAL-EARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR---NNKEYEALQK 96

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290  880 G-ESLKKLQQQLEQKTLGH----EKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 937
Cdd:COG1579     97 EiESLKRRISDLEDEILELmeriEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
812-1033 5.83e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 5.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  812 LAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFqkKQSESEVHLQEIKAQNTQKdfelvesgesLKKLQQQLE 891
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEF--RQKNGLVDLSEEAKLLLQQ----------LSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  892 QKTLGHEKLQAALEELKKEKETIIKE-----KEQELQQLQSKSAESESALKVVQVQLEqlqqqaaasgeEGSKTVAKLHD 966
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDAlpellQSPVIQQLRAQLAELEAELAELSARYT-----------PNHPDVIALRA 298

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290  967 EISQLKSQ----AEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSS 1033
Cdd:COG3206    299 QIAALRAQlqqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYES 369
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
507-1076 6.45e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 6.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  507 KKKLFPLKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESkitklvsatpslqsilppdlps 586
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE---------------------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  587 ddgalQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIatlqSELVSKDEALEKFSLSECGIENLRrele 666
Cdd:PRK03918   288 -----LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI----KELEEKEERLEELKKKLKELEKRL---- 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  667 llkeenekqaqeaqaEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKT-DECEILQTEVRmrdEQIRELNQQLDE 745
Cdd:PRK03918   355 ---------------EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKElEELEKAKEEIE---EEISKITARIGE 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  746 VTTQLNVQKADSSALDDMLRL----QKEGTEE-KSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVR 820
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAKGKcpvcGRELTEEhRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  821 EMTENAINQIQLEKEsieqqlaLKQNELEDFQKKQSESEvhlqeikaqntqkdfELVESGESLKKLQQQLEQKTLGHEKL 900
Cdd:PRK03918   497 KLKELAEQLKELEEK-------LKKYNLEELEKKAEEYE---------------KLKEKLIKLKGEIKSLKKELEKLEEL 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  901 QAALEELKKEKETIIKEKEQELQQLQSKSAESESALkvvqvqleqlqqqaaasgEEGSKTVAKLHDEISQLK---SQAEE 977
Cdd:PRK03918   555 KKKLAELEKKLDELEEELAELLKELEELGFESVEEL------------------EERLKELEPFYNEYLELKdaeKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  978 TQSELKSTQSNLEAKSKQLEAANGSLEEEAKKsghlLEQITKLKSEvgETQAALSSCHTdveSKTKQLEAANAALEKVNK 1057
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSE--EEYEELREEYL---ELSRELAGLRAELEELEK 687

                          570
                   ....*....|....*....
gi 1834199290 1058 EYAESRAEASDLQDKVKEI 1076
Cdd:PRK03918   688 RREEIKKTLEKLKEELEER 706
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1295-1642 7.20e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 7.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1295 KFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKeelvQNLEEKVRESSSIIEAQNTKLNESNVQLE 1374
Cdd:TIGR00606  183 RYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSK----EAQLESSREIVKSYENELDPLKNRLKEIE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1375 NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQV-QEANGDIKDSLVKVEELVKVLEEKLQAATSQLdaqQATNKEL 1453
Cdd:TIGR00606  259 HNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVfQGTDEQLNDLYHNHQRTVREKERELVDCQREL---EKLNKER 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1454 QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKE----------------LQGKLDESNTVlesqK 1517
Cdd:TIGR00606  336 RLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFErgpfserqiknfhtlvIERQEDEAKTA----A 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1518 KSHNEIQDKLEQAQQK-----------ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKvi 1586
Cdd:TIGR00606  412 QLCADLQSKERLKQEQadeirdekkglGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSK-- 489

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1587 deMDDAASVKSALLEQ--LQNRVAELETALRQanDAQKTAYLE-TKELRRQLESLELEK 1642
Cdd:TIGR00606  490 --AEKNSLTETLKKEVksLQNEKADLDRKLRK--LDQEMEQLNhHTTTRTQMEMLTKDK 544
PRK12704 PRK12704
phosphodiesterase; Provisional
 1274-1458 8.54e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 50.55  E-value: 8.54e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1274 KVTGIKEELKEThlqLDERQKKFEEL-EEKLKQAQQSEQKLQQE-SQTSKEKLTEIQQslqeLQDSVKQKEELVQNLEEK 1351
Cdd:PRK12704    32 KIKEAEEEAKRI---LEEAKKEAEAIkKEALLEAKEEIHKLRNEfEKELRERRNELQK----LEKRLLQKEENLDRKLEL 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1352 VRESSSIIEAQNTKLNESNVQLENKtsclKETQDQLLESQKKEkqlQEEAAKLSGElqqvqEANgdikdslvkvEELVKV 1431
Cdd:PRK12704   105 LEKREEELEKKEKELEQKQQELEKK----EEELEELIEEQLQE---LERISGLTAE-----EAK----------EILLEK 162

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1834199290 1432 LEEKLQAATSQL------DAQQATNKELQELLV 1458
Cdd:PRK12704   163 VEEEARHEAAVLikeieeEAKEEADKKAKEILA 195
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1208-1449 8.67e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 8.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1208 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQaeksetnhifelfemEADMNSERLIEKVTGIKEELKETHL 1287
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA---------------ALERRIAALARRIRALEQELAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1288 QLDERQKKFEELEEKLKQAQQSEQK----LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVREsssiIEAQN 1363
Cdd:COG4942     84 ELAELEKEIAELRAELEAQKEELAEllraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE----LRADL 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1364 TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQL 1443
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239


                   ....*.
gi 1834199290 1444 DAQQAT 1449
Cdd:COG4942    240 AERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1013-1617 9.43e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 9.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1013 LLEQITKLKSEVGEtqaaLSSCHTDVESKTKQLEAAnAALEKVNKEYAESRAEASDLQD--------KVKEITDTLHAEL 1084
Cdd:COG4913    223 TFEAADALVEHFDD----LERAHEALEDAREQIELL-EPIRELAERYAAARERLAELEYlraalrlwFAQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1085 QAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLqdsqdsqTKLKAEGERKEKSFEESIKN 1164
Cdd:COG4913    298 EELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL-------ERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1165 LQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVL- 1243
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALa 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1244 EVLQAEKSETNHIFELFEMEADMNS-----ERLI--------------EKVTGIKEELK-ETHLQLderqkkfeeleEKL 1303
Cdd:COG4913    451 EALGLDEAELPFVGELIEVRPEEERwrgaiERVLggfaltllvppehyAAALRWVNRLHlRGRLVY-----------ERV 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1304 KQAQQSEQKLQQESQTSKEKLT--------EIQQSLQELQDSVKqkeelVQNLEEKVRESSSI-IEAQ------------ 1362
Cdd:COG4913    520 RTGLPDPERPRLDPDSLAGKLDfkphpfraWLEAELGRRFDYVC-----VDSPEELRRHPRAItRAGQvkgngtrhekdd 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1363 NTKLNESNV-------QLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSG---ELQQVQEANGDIKDslvkveelVKVL 1432
Cdd:COG4913    595 RRRIRSRYVlgfdnraKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEID--------VASA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1433 EEKLQAATSQLDAQQATNKELQELlvksQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE---- 1508
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAAL----EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedl 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1509 --SNTVLESQKKSHNEIQDKLEqaQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLekGNEFDTQLAEYQKVI 1586
Cdd:COG4913    743 arLELRALLEERFAAALGDAVE--RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAE--TADLDADLESLPEYL 818

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 1834199290 1587 DEMDDAASV---------KSALLEQLQNRVAELETALRQA 1617
Cdd:COG4913    819 ALLDRLEEDglpeyeerfKELLNENSIEFVADLLSKLRRA 858
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 515-1367 1.22e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  515 ARIVELESALDNERKKTEELQCSIDEAQfcgdeLNAQSQVYKEKIHDLESKITKLVSATPSLQSilppdlpsddgaLQEE 594
Cdd:pfam12128  204 AILEDDGVVPPKSRLNRQQVEHWIRDIQ-----AIAGIMKIRPEFTKLQQEFNTLESAELRLSH------------LHFG 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  595 IAKLQEKMTIQQKEVESRIAEQleeEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEK 674
Cdd:pfam12128  267 YKSDETLIASRQEERQETSAEL---NQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAA 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  675 QAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERV--NKTDECEILQTEVRMRDEQIRelnqqldevttQLNV 752
Cdd:pfam12128  344 ADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKeqNNRDIAGIKDKLAKIREARDR-----------QLAV 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  753 QKADSSALDDMLRLQKEG-----TEEKSTLLEKTEKELVQsKEQAAKTLNDKEQLEKQISDLKQLAE-QEKLVREMTENA 826
Cdd:pfam12128  413 AEDDLQALESELREQLEAgklefNEEEYRLKSRLGELKLR-LNQATATPELLLQLENFDERIERAREeQEAANAEVERLQ 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  827 INQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEE 906
Cdd:pfam12128  492 SELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWD 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  907 LKKEKETIIKEKEQELQQLQsksaesesalkvvqvqleqlqqqaaasgeegsktVAKLHDEISQLKSQAEETQSELKSTQ 986
Cdd:pfam12128  572 GSVGGELNLYGVKLDLKRID----------------------------------VPEWAASEEELRERLDKAEEALQSAR 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  987 SNLEAKSKQLEAANGSLEEEAKKsghLLEQITKLKSEvGETQAALSSCHTDVESK-TKQLEAANA-ALEKVNKEYAESRA 1064
Cdd:pfam12128  618 EKQAAAEEQLVQANGELEKASRE---ETFARTALKNA-RLDLRRLFDEKQSEKDKkNKALAERKDsANERLNSLEAQLKQ 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1065 EASDLQDKVKEITDTL----HAELQAERSSSSALHTKLSKFSDEIA---TGHKELTSKADAWSQEMLQK----------- 1126
Cdd:pfam12128  694 LDKKHQAWLEEQKEQKrearTEKQAYWQVVEGALDAQLALLKAAIAarrSGAKAELKALETWYKRDLASlgvdpdviakl 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1127 EKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAELQhKEK 1206
Cdd:pfam12128  774 KREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISEL----QQQLARLIADTKLRRAKLE-MER 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1207 MASEDAQ---------------KIADLKTLVEAIQvANANISATNAELSTVLEVLQAEKSETNHIFELFE--MEADMNS- 1268
Cdd:pfam12128  849 KASEKQQvrlsenlrglrcemsKLATLKEDANSEQ-AQGSIGERLAQLEDLKLKRDYLSESVKKYVEHFKnvIADHSGSg 927

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 -----ERLIEKVTGIKEELkethLQLDERQKKFEELEEKLK-QAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVK-QK 1341
Cdd:pfam12128  928 laetwESLREEDHYQNDKG----IRLLDYRKLVPYLEQWFDvRVPQSIMVLREQVSILGVDLTEFYDVLADFDRRIAsFS 1003

                          890       900       910
                   ....*....|....*....|....*....|.
gi 1834199290 1342 EELVQNLE-----EKVRESSSIIEAQNTKLN 1367
Cdd:pfam12128 1004 RELQREVGeeaffEGVSESAVRIRSKVSELE 1034
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 792-1009 1.45e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  792 AAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQ 871
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  872 KDFELVESGESLKKL---QQQLEQKT-----------LGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALK 937
Cdd:COG4942     95 LRAELEAQKEELAELlraLYRLGRQPplalllspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834199290  938 VVqvqleqlqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK 1009
Cdd:COG4942    175 EL---------------EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
46 PHA02562
endonuclease subunit; Provisional
 1186-1424 1.54e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1186 TIKDLQERLE-ITNAELQHKEKMASEDAQKIADLKTLVEAIQVAnanisatnaelstVLEVLQAEKSETNHIFELFEMEA 1264
Cdd:PHA02562   199 TYNKNIEEQRkKNGENIARKQNKYDELVEEAKTIKAEIEELTDE-------------LLNLVMDIEDPSAALNKLNTAAA 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1265 DMNSErlIEKVTGIKEELKETHL------QLDERQKKFEELEEKLKQAQQSEQKL---QQESQTSKEKLTEIQQSLQELQ 1335
Cdd:PHA02562   266 KIKSK--IEQFQKVIKMYEKGGVcptctqQISEGPDRITKIKDKLKELQHSLEKLdtaIDELEEIMDEFNEQSKKLLELK 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1336 DSVKQKEELVQNLEEKVRESSSIIEaqntKLNESNVqleNKTSCLKETQDQLlesqkkeKQLQEEAAKLSGELQQVQEAN 1415
Cdd:PHA02562   344 NKISTNKQSLITLVDKAKKVKAAIE----ELQAEFV---DNAEELAKLQDEL-------DKIVKTKSELVKEKYHRGIVT 409


                   ....*....
gi 1834199290 1416 GDIKDSLVK 1424
Cdd:PHA02562   410 DLLKDSGIK 418
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1200-1647 1.60e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 49.82  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1200 ELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEK--SETNHIFELFEMEADMN-SERLIEKVT 1276
Cdd:pfam10174  213 EELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGllHTEDREEEIKQMEVYKShSKFMKNKID 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1277 GIKEEL--KETHL------------QLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1342
Cdd:pfam10174  293 QLKQELskKESELlalqtkletltnQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1343 ELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDI---- 1418
Cdd:pfam10174  373 EEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKerii 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1419 --------KDSLVKVEELvKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1490
Cdd:pfam10174  453 erlkeqreREDRERLEEL-ESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKE 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1491 ALCQKENGLKELQGkldesntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQlllE 1570
Cdd:pfam10174  532 ECSKLENQLKKAHN--------AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKD---K 600

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1571 KGNEFDTQLAEYQKviDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAyletkeLRRQLESL--ELEKSREVL 1647
Cdd:pfam10174  601 KIAELESLTLRQMK--EQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNS------QQLQLEELmgALEKTRQEL 671
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1299-1574 1.79e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 49.13  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1299 LEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTS 1378
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1379 CLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLV 1458
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1459 KSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQ 1538
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1834199290 1539 EETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNE 1574
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNL 304
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 835-1417 1.93e-05

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 49.75  E-value: 1.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  835 ESIEQQLALKQNELEDFQKKQSEsevhLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETI 914
Cdd:pfam07111   59 QALSQQAELISRQLQELRRLEEE----VRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  915 IKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTV----AKLHDEISQLKSQAEETQSELKSTQSNLE 990
Cdd:pfam07111  135 EEGSQRELEEIQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLetkrAGEAKQLAEAQKEAELLRKQLSKTQEELE 214

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  991 AKSKQLEAANGSLEEEAKKSGH----------LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEK------ 1054
Cdd:pfam07111  215 AQVTLVESLRKYVGEQVPPEVHsqtwelerqeLLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELTRkiqpsd 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1055 -VNKEYAES-RAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSkfsdeiatghkELTSKADAWSQEMLQKEKELQE 1132
Cdd:pfam07111  295 sLEPEFPKKcRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVA-----------ELQEQVTSQSQEQAILQRALQD 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1133 LRQQLQDSQDSQTKLKAEGERKEKSfeesiKNLQEEVTKAKTENLELSTG----TQTTIKDLQERLEITNAELQHKEKMA 1208
Cdd:pfam07111  364 KAAEVEVERMSAKGLQMELSRAQEA-----RRRQQQQTASAEEQLKFVVNamssTQIWLETTMTRVEQAVARIPSLSNRL 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1209 SEDAQKIADLKTLVeAIQVANANISA-----------TNAELSTVLEVLQAEKSETNHIFELfemeadmnSERLIEKVTG 1277
Cdd:pfam07111  439 SYAVRKVHTIKGLM-ARKVALAQLRQescpppppappVDADLSLELEQLREERNRLDAELQL--------SAHLIQQEVG 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKEThlqlderqkkfeELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDS-----------VKQKEELVQ 1346
Cdd:pfam07111  510 RAREQGEA------------ERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESteeaaslrqelTQQQEIYGQ 577

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1347 NLEEKVRESSSIIEAQ--NTKLNESNVQLENKTSCLKETQDQLLESQKKE-----KQLQEEAAKLSGE--LQQVQEANGD 1417
Cdd:pfam07111  578 ALQEKVAEVETRLREQlsDTKRRLNEARREQAKAVVSLRQIQHRATQEKErnqelRRLQDEARKEEGQrlARRVQELERD 657
PRK11281 PRK11281
mechanosensitive channel MscK;
1081-1618 2.00e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.91  E-value: 2.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1081 HAELQAERSSSSALHTKLSKFSD-EIATGHKELTSKADAWSQEMLQK----EKELQELRqqlqdsqdsqtKLKAEGERKE 1155
Cdd:PRK11281    28 RAASNGDLPTEADVQAQLDALNKqKLLEAEDKLVQQDLEQTLALLDKidrqKEETEQLK-----------QQLAQAPAKL 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1156 KSFEESIKNLQEEVTKAKTENLElstgtQTTIKDLQERLEITNAELQhkekmaseDAQkiadlktlvEAIQVANANISAt 1235
Cdd:PRK11281    97 RQAQAELEALKDDNDEETRETLS-----TLSLRQLESRLAQTLDQLQ--------NAQ---------NDLAEYNSQLVS- 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1236 naeLSTVLEVLQAEKSEtnhifelfemeadmNSERLiekvtgikeelkethlqlderqkkfEELEEKLKQAQQSEQKLQQ 1315
Cdd:PRK11281   154 ---LQTQPERAQAALYA--------------NSQRL-------------------------QQIRNLLKGGKVGGKALRP 191

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1316 ESQTskekLTEIQQSLQELQDSVKQKE----ELVQNLEEKVREsssiieaqntKLNESNVQLEnktsclKETQD-QLLES 1390
Cdd:PRK11281   192 SQRV----LLQAEQALLNAQNDLQRKSlegnTQLQDLLQKQRD----------YLTARIQRLE------HQLQLlQEAIN 251

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1391 QKKEKQLQEEAAklsgELQQVQEANGDIKDSLVKveelvkvleeklqaatsqldAQQATNKELQELLVKSqenegnlqge 1470
Cdd:PRK11281   252 SKRLTLSEKTVQ----EAQSQDEAARIQANPLVA--------------------QELEINLQLSQRLLKA---------- 297

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1471 slavTEKLQQLEQANGELK---EALCQKENGLKE----LQGKLdesntVLesqkkshNEIqdkLEQAQQKERTLQeETSK 1543
Cdd:PRK11281   298 ----TEKLNTLTQQNLRVKnwlDRLTQSERNIKEqisvLKGSL-----LL-------SRI---LYQQQQALPSAD-LIEG 357

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1544 LAEQLSQLKQAneelQKSLQQKQLLLEKGNEFDTQLAEYQKVidEMDDAasVKSALLEQLQNRVAELETALRQAN 1618
Cdd:PRK11281   358 LADRIADLRLE----QFEINQQRDALFQPDAYIDKLEAGHKS--EVTDE--VRDALLQLLDERRELLDQLNKQLN 424
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1269-1408 2.21e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 2.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQ---ESQTSKEkLTEIQQSLQELQDSVKQKEELV 1345
Cdd:COG1579     34 AELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgNVRNNKE-YEALQKEIESLKRRISDLEDEI 112

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1346 QNLEEKVRESSSIIEAQNTKLNESNVQLENKTsclKETQDQLLESQKKEKQLQEEAAKLSGEL 1408
Cdd:COG1579    113 LELMERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAELEELEAEREELAAKI 172
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 899-1066 2.30e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 47.61  E-value: 2.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  899 KLQAALEELKKEKETI---IKEKEQELQQLQSKSAESESALKVVQvqleqlqqqaaasgeegsKTVAKLHDEISQLKSQA 975
Cdd:COG1579     14 ELDSELDRLEHRLKELpaeLAELEDELAALEARLEAAKTELEDLE------------------KEIKRLELEIEEVEARI 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  976 EETQSELKSTQSN--LEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALE 1053
Cdd:COG1579     76 KKYEEQLGNVRNNkeYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155

                          170
                   ....*....|...
gi 1834199290 1054 KVNKEYAESRAEA 1066
Cdd:COG1579    156 AELEELEAEREEL 168
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1171-1527 2.68e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 2.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1171 KAKTENLELSTGTQTTIKDLQERLEiTNAELQHKEKMASEDAQKIADlkTLVEAIQVANANISATNAELSTVLEVLQAEK 1250
Cdd:PLN02939    36 RARRRGFSSQQKKKRGKNIAPKQRS-SNSKLQSNTDENGQLENTSLR--TVMELPQKSTSSDDDHNRASMQRDEAIAAID 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1251 SETNHIFELFEMEADMNSERLIEKvtgIKEELKETHLQLDERQKKFEELEEKLKQaqqsEQKLQQESQTSKEKLTEIQQS 1330
Cdd:PLN02939   113 NEQQTNSKDGEQLSDFQLEDLVGM---IQNAEKNILLLNQARLQALEDLEKILTE----KEALQGKINILEMRLSETDAR 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1331 LQeLQDSVKQKEELVQNLEEKVRESSSIIEAQN-----------TKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQE 1399
Cdd:PLN02939   186 IK-LAAQEKIHVEILEEQLEKLRNELLIRGATEglcvhslskelDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEK 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1400 EAAKLSGELQQVQ----EANGDI-KDSLVKVE---ELVKVLEEKLQAATSQLDAQQAT---NKELQELLVKSQEN--EGN 1466
Cdd:PLN02939   265 ERSLLDASLRELEskfiVAQEDVsKLSPLQYDcwwEKVENLQDLLDRATNQVEKAALVldqNQDLRDKVDKLEASlkEAN 344

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1467 LQGESLAVTEKLQQ--------LEQANGELKEALCQKENGLKELQGKLdeSNTVLESQKKSHNEIQDKL 1527
Cdd:PLN02939   345 VSKFSSYKVELLQQklklleerLQASDHEIHSYIQLYQESIKEFQDTL--SKLKEESKKRSLEHPADDM 411
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1183-1590 3.04e-05

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 48.68  E-value: 3.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1183 TQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQvanANISATNAELSTVLEVLQAEKSETNHIFELFE- 1261
Cdd:PRK04778   110 IESLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSFGPALDELEKQLENLEEEFSQFVe 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1262 -------MEADMNSERLIEKVTGIKEELKETHLQLDERQKKF----EELEEKLKQAQQS-----EQKLQQESQTSKEKLT 1325
Cdd:PRK04778   187 ltesgdyVEAREILDQLEEELAALEQIMEEIPELLKELQTELpdqlQELKAGYRELVEEgyhldHLDIEKEIQDLKEQID 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1326 EIQQSLQELQdsVKQKEELVQNLEEKVRESSSIIEaqnTKLNESNVQLENKtsclKETQDQLLESQKKEKQLQEEAAKLS 1405
Cdd:PRK04778   267 ENLALLEELD--LDEAEEKNEEIQERIDQLYDILE---REVKARKYVEKNS----DTLPDFLEHAKEQNKELKEEIDRVK 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1406 -------GELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATS---QLDAQQATNKELQELLVKSQENEGNLQGESLAVT 1475
Cdd:PRK04778   338 qsytlneSELESVRQLEKQLESLEKQYDEITERIAEQEIAYSElqeELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAR 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1476 EKLQQLEQANGELKEALcQKEN--GL--------KELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSK-- 1543
Cdd:PRK04778   418 EKLERYRNKLHEIKRYL-EKSNlpGLpedylemfFEVSDEIEALAEELEEKPINMEAVNRLLEEATEDVETLEEETEElv 496

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1544 ----LAEQLSQ----LKQANEELQKSLQQKQLLLeKGNEFDTQLAEYQKVIDEMD 1590
Cdd:PRK04778   497 enatLTEQLIQyanrYRSDNEEVAEALNEAERLF-REYDYKAALEIIATALEKVE 550
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1331-1555 3.83e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 3.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1331 LQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQ 1410
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1411 vQEANGDIKDSLVKVEEL------VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQA 1484
Cdd:COG3883     98 -SGGSVSYLDVLLGSESFsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1485 NGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1555
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAA 247
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 963-1657 3.86e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 48.64  E-value: 3.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  963 KLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAkksgHLLEQITKLKSEVGETQAALSSCHTDVESKT 1042
Cdd:PRK10246   202 KLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSL----NWLTRLDELQQEASRRQQALQQALAAEEKAQ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1043 KQLEAAN-------------------AALEKVNKEYAESRA---EASDLQDKVKEITDTLHAELQAERSSSS---ALHTK 1097
Cdd:PRK10246   278 PQLAALSlaqparqlrphweriqeqsAALAHTRQQIEEVNTrlqSTMALRARIRHHAAKQSAELQAQQQSLNtwlAEHDR 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1098 LSKFSDEIATGHKELT------SKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTK 1171
Cdd:PRK10246   358 FRQWNNELAGWRAQFSqqtsdrEQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVP 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1172 AKTENLELstgtQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAiqvananiSATNAELSTVLEVLQAEK- 1250
Cdd:PRK10246   438 QQKRLAQL----QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQ--------EARIKDLEAQRAQLQAGQp 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1251 ----SETNH--IFELFEMEADMNSERL--IEK-VTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSK 1321
Cdd:PRK10246   506 cplcGSTSHpaVEAYQALEPGVNQSRLdaLEKeVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVC 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1322 EKLTEIQQSLQELQDSVKQKEELVQNLEE--KVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQL---LESQKKEKQ 1396
Cdd:PRK10246   586 ASLNITLQPQDDIQPWLDAQEEHERQLRLlsQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYaltLPQEDEEAS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1397 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQgeslavte 1476
Cdd:PRK10246   666 WLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEETVALDNWRQVHEQCLSLHSQLQTLQ-------- 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1477 klQQLEQANGELKEALCQKENGLKelqgkldesNTVLESqkkshneiqdkleQAQQKERTLQEETsklAEQLSQLKQAne 1556
Cdd:PRK10246   738 --QQDVLEAQRLQKAQAQFDTALQ---------ASVFDD-------------QQAFLAALLDEET---LTQLEQLKQN-- 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1557 eLQKSLQQKQLLLEKGNEfdtQLAEYQKVIDE-MDDAASVksallEQLQNRVAELETALRQANDAQktayletKELRRQL 1635
Cdd:PRK10246   789 -LENQRQQAQTLVTQTAQ---ALAQHQQHRPDgLDLTVTV-----EQIQQELAQLAQQLRENTTRQ-------GEIRQQL 852

                          730       740
                   ....*....|....*....|..
gi 1834199290 1636 ESlELEKSREVLSLKAQMNGAS 1657
Cdd:PRK10246   853 KQ-DADNRQQQQALMQQIAQAT 873
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1473-1678 4.41e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 4.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1473 AVTEKLQQLEQANGELKEALCQKengLKELQGKLDEsntvLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLK 1552
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKE---LKELEEELKE----AEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1553 QANE------ELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMD----DAASVKSALLEQLQNRVAELETALRQANDAQK 1622
Cdd:COG4717    123 KLLQllplyqELEALEAELAELPERLEELEERLEELRELEEELEeleaELAELQEELEELLEQLSLATEEELQDLAEELE 202

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1623 TAYLETKELRRQLESLELEKSRevlsLKAQMNGASSRSGKGDEVESLDIETSLAKI 1678
Cdd:COG4717    203 ELQQRLAELEEELEEAQEELEE----LEEELEQLENELEAAALEERLKEARLLLLI 254
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1026-1763 4.56e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 48.89  E-value: 4.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1026 ETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITD------TLHAELQAERSSSSALHTKLS 1099
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDeiiyinKLKLELKEKIKNISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1100 KfsdeiATGHKELTSKADAWSQEmLQKEKELQELRQQLQDSQDSQTkLKAEgerKEKSFEESIKNLQEEVTKAKTENLEL 1179
Cdd:TIGR01612  621 K-----AIDLKKIIENNNAYIDE-LAKISPYQVPEHLKNKDKIYST-IKSE---LSKIYEDDIDALYNELSSIVKENAID 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1180 STGTQTTIKDLQERLEITNAELQHKEKMASE------DAQKIADLKTLVEAIQVANANIsatNAELSTVLEVLQA-EKSE 1252
Cdd:TIGR01612  691 NTEDKAKLDDLKSKIDKEYDKIQNMETATVElhlsniENKKNELLDIIVEIKKHIHGEI---NKDLNKILEDFKNkEKEL 767

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1253 TNHIFELFEMEADMNSERliEKVTGIK--------------EELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE-- 1316
Cdd:TIGR01612  768 SNKINDYAKEKDELNKYK--SKISEIKnhyndqinidnikdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDfl 845

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1317 ---------SQTSKEKLTEIQQSLQELQDSVKQK--EELVQNLEEKVRESSSIIEAQNTKLNE--SNVQLENKTS----C 1379
Cdd:TIGR01612  846 nkvdkfinfENNCKEKIDSEHEQFAELTNKIKAEisDDKLNDYEKKFNDSKSLINEINKSIEEeyQNINTLKKVDeyikI 925

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1380 LKETQDQLLESQKKEKQLQEeaaKLSGELQQVQEAN-------GDIKDSLV-KVEELVKVLEEklqaatSQLDAQQATNK 1451
Cdd:TIGR01612  926 CENTKESIEKFHNKQNILKE---ILNKNIDTIKESNlieksykDKFDNTLIdKINELDKAFKD------ASLNDYEAKNN 996

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1452 ELQELLVKSQENEGNLQGESL---------AVTEKLQQLEQANGELKE-------ALCQKENGLKELQGKLDES--NTVL 1513
Cdd:TIGR01612  997 ELIKYFNDLKANLGKNKENMLyhqfdekekATNDIEQKIEDANKNIPNieiaihtSIYNIIDEIEKEIGKNIELlnKEIL 1076

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1514 ESQKKS---HNEIQDKLEQAQQKErTLQEETSKLAEQLSQLKQ----ANEELQKSLQQKQLLLEKG----NEFDTQLAEY 1582
Cdd:TIGR01612 1077 EEAEINitnFNEIKEKLKHYNFDD-FGKEENIKYADEINKIKDdiknLDQKIDHHIKALEEIKKKSenyiDEIKAQINDL 1155

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1583 QKVIDEMDDAASVKSaLLEQLQNRVAELetalrqanDAQKTAYLETKELRRQLESLELEKSrevlSLKaQMNGASSRSGK 1662
Cdd:TIGR01612 1156 EDVADKAISNDDPEE-IEKKIENIVTKI--------DKKKNIYDEIKKLLNEIAEIEKDKT----SLE-EVKGINLSYGK 1221

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1663 gdevesldietSLAKInFLNSIIADMQQKNDALKAKVQTLETLpmdftkphafDALTKRKPAPRLFCDICDEFDQhDTED 1742
Cdd:TIGR01612 1222 -----------NLGKL-FLEKIDEEKKKSEHMIKAMEAYIEDL----------DEIKEKSPEIENEMGIEMDIKA-EMET 1278

                          810       820
                   ....*....|....*....|.
gi 1834199290 1743 CPIQGSEDQDYSTPSSESNNN 1763
Cdd:TIGR01612 1279 FNISHDDDKDHHIISKKHDEN 1299
PRK01156 PRK01156
chromosome segregation protein; Provisional
 685-1363 5.11e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.36  E-value: 5.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  685 RKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDeceiLQTEVRMRDEQIRELNQQLDEvttqlnvqkaDSSALDDML 764
Cdd:PRK01156   152 KKILDEILEINSLERNYDKLKDVIDMLRAEISNIDY----LEEKLKSSNLELENIKKQIAD----------DEKSHSITL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  765 RLQKEGTEEkstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQlAEQEKLVREMTENAINQIQLEKESIEQQLAL- 843
Cdd:PRK01156   218 KEIERLSIE----YNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT-AESDLSMELEKNNYYKELEERHMKIINDPVYk 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  844 KQNELEDFQKKQSESEVHLQEIKaqntQKDFELVESGESLKKLQQQleqktlghEKLQAALEELKKEKETIikekEQELQ 923
Cdd:PRK01156   293 NRNYINDYFKYKNDIENKKQILS----NIDAEINKYHAIIKKLSVL--------QKDYNDYIKKKSRYDDL----NNQIL 356

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  924 QLQSKSAESESALKVVQVQLEQLqqqaaasgEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSL 1003
Cdd:PRK01156   357 ELEGYEMDYNSYLKSIESLKKKI--------EEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSL 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1004 EEEAKKSGHLLEQITKlKSEVGETQAALSSCHTDV-ESKTKQL-EAANAALEKVNKEYAESRAEASDLQDKVKEitdtlh 1081
Cdd:PRK01156   429 NQRIRALRENLDELSR-NMEMLNGQSVCPVCGTTLgEEKSNHIiNHYNEKKSRLEEKIREIEIEVKDIDEKIVD------ 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1082 aelqaerssssalhtkLSKFSDEIATGHKEltskadawsqEMLQKEKELQELRQQLQDSQDSQTKLKaEGERKEKSFEES 1161
Cdd:PRK01156   502 ----------------LKKRKEYLESEEIN----------KSINEYNKIESARADLEDIKIKINELK-DKHDKYEEIKNR 554

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1162 IKNLQEEVTKAKTE--NLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEaiqvananisatnael 1239
Cdd:PRK01156   555 YKSLKLEDLDSKRTswLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYID---------------- 618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1240 STVLEVLQAEKSETNHIFELFEMEadmnseRLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT 1319
Cdd:PRK01156   619 KSIREIENEANNLNNKYNEIQENK------ILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDD 692

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1834199290 1320 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQN 1363
Cdd:PRK01156   693 AKANRARLESTIEILRTRINELSDRINDINETLESMKKIKKAIG 736
PRK11281 PRK11281
mechanosensitive channel MscK;
774-1021 6.25e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.98  E-value: 6.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  774 KSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQ-LAEQEKLVREMTEN---------AINQIQLEKESI---EQQ 840
Cdd:PRK11281    50 KQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQqLAQAPAKLRQAQAElealkddndEETRETLSTLSLrqlESR 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  841 LALKQNELEDFQKK-----------QSESE----------VHLQEIKAQ-NTQKDFELVESGESLKKLQQQL-------- 890
Cdd:PRK11281   130 LAQTLDQLQNAQNDlaeynsqlvslQTQPEraqaalyansQRLQQIRNLlKGGKVGGKALRPSQRVLLQAEQallnaqnd 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  891 -EQKTL-GHEKLQAALEELKKEKETIIKEKEQELQQLQskSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAK---LH 965
Cdd:PRK11281   210 lQRKSLeGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ--EAINSKRLTLSEKTVQEAQSQDEAARIQANPLVAQeleIN 287

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290  966 DEISQLKSQAEETQSELksTQSNLEAKSkQLEAANGSleEEAKKsghllEQITKLK 1021
Cdd:PRK11281   288 LQLSQRLLKATEKLNTL--TQQNLRVKN-WLDRLTQS--ERNIK-----EQISVLK 333
PRK01156 PRK01156
chromosome segregation protein; Provisional
 886-1490 7.10e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.97  E-value: 7.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  886 LQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgEEGSKTVAKLH 965
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNL-------------------KSALNELSSLE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  966 DEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQL 1045
Cdd:PRK01156   249 DMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAII 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1046 EAAnAALEKVNKEYAESRAEASDLQDKVKEItDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQ 1125
Cdd:PRK01156   329 KKL-SVLQKDYNDYIKKKSRYDDLNNQILEL-EGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDA 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1126 KEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTT---IKDLQERLEITNAELQ 1202
Cdd:PRK01156   407 IKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSnhiINHYNEKKSRLEEKIR 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1203 HKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVlqaeksetnhifelfEMEADMNSErliekvtgikEEL 1282
Cdd:PRK01156   487 EIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARA---------------DLEDIKIKI----------NEL 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1283 KETHL---QLDERQK--KFEELEEKlkqaqqSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSS 1357
Cdd:PRK01156   542 KDKHDkyeEIKNRYKslKLEDLDSK------RTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1358 IIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSlvkvEELVKVLEEKLQ 1437
Cdd:PRK01156   616 YIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI----EDNLKKSRKALD 691

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1438 AATSQLDAQQATNKEL----QELLVKSQENEGNLqgeslavtEKLQQLEQANGELKE 1490
Cdd:PRK01156   692 DAKANRARLESTIEILrtriNELSDRINDINETL--------ESMKKIKKAIGDLKR 740
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 1304-1560 7.32e-05

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 47.11  E-value: 7.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1304 KQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEA---QNTKLNESNVQLENKTSCL 1380
Cdd:pfam15905   55 KVKSLELKKKSQKNLKESKDQKELEKEIRALVQERGEQDKRLQALEEELEKVEAKLNAavrEKTSLSASVASLEKQLLEL 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1381 KETQDqLLESQKKEKQLQEEAAKLSGELQQVQ-EANGDIKDSLVKVEELvkvlEEKLQAATSQLDAQQATNKELQELLVK 1459
Cdd:pfam15905  135 TRVNE-LLKAKFSEDGTQKKMSSLSMELMKLRnKLEAKMKEVMAKQEGM----EGKLQVTQKNLEHSKGKVAQLEEKLVS 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1460 S--QENEGNLQGESL--------AVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHN-------- 1521
Cdd:pfam15905  210 TekEKIEEKSETEKLleyitelsCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNekcklles 289

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1834199290 1522 EIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQK 1560
Cdd:pfam15905  290 EKEELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQ 328
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 862-1093 7.93e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 7.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  862 LQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEketiIKEKEQELQQLQSKSAESESALKVVQV 941
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  942 QLEQLQQQAAASGE-EGSKTVAKLHDEISQLKSQAEETQS---ELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQI 1017
Cdd:COG3883     94 ALYRSGGSVSYLDVlLGSESFSDFLDRLSALSKIADADADlleELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1018 TKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSA 1093
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 561-1091 9.18e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 9.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  561 DLESKITKLVSATPSLQSilppDLPSDDGALQEEI-AKLQEKMTIQQKEVE-SRIAEQLEEEQRLRENVKylnEQIATLQ 638
Cdd:pfam01576  451 EAEGKNIKLSKDVSSLES----QLQDTQELLQEETrQKLNLSTRLRQLEDErNSLQEQLEEEEEAKRNVE---RQLSTLQ 523

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  639 SELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRklAEKSVEVLR-----LSSELQNLKATSDSLEs 713
Cdd:pfam01576  524 AQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDK--LEKTKNRLQqelddLLVDLDHQRQLVSNLE- 600

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  714 ERVNKTDEC--EILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDdmlrlQKEGTEEKSTLLEKTEKELVQSKEQ 791
Cdd:pfam01576  601 KKQKKFDQMlaEEKAISARYAEERDRAEAEAREKETRALSLARALEEALE-----AKEELERTNKQLRAEMEDLVSSKDD 675

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  792 AAKTLNDkeqLEKQisdlKQLAEQEKlvremtenainqiqlekESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQ 871
Cdd:pfam01576  676 VGKNVHE---LERS----KRALEQQV-----------------EEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFER 731

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  872 KDFELVESGESLKK-LQQQLEQktlghekLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVqvqleqlqqqa 950
Cdd:pfam01576  732 DLQARDEQGEEKRRqLVKQVRE-------LEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGR----------- 793

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  951 aasgEEGSKTVAKLHDEISQLKSQAEETQS---ELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGET 1027
Cdd:pfam01576  794 ----EEAVKQLKKLQAQMKDLQRELEEARAsrdEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADE 869

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1028 QAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSS 1091
Cdd:pfam01576  870 IASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTS 933
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
610-854 9.38e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 9.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  610 ESRIAEQLEEEQRLRENVKYLNEQIATLQSELvskdEALEKFSLSECGIENLRRELELLKeenekQAQEAQAEFTRKLAE 689
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAEL----DALQERREALQRLAEYSWDEIDVA-----SAEREIAELEAELER 679

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  690 ksveVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNvqkadssalddmlRLQKE 769
Cdd:COG4913    680 ----LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE-------------AAEDL 742

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  770 GTEEKSTLLEKTEKELVQSKEQAAKtlndKEQLEKQISDLKQLAEQ--EKLVREMTE------NAINQIQLEKESIEQQL 841
Cdd:COG4913    743 ARLELRALLEERFAAALGDAVEREL----RENLEERIDALRARLNRaeEELERAMRAfnrewpAETADLDADLESLPEYL 818

                          250
                   ....*....|....*..
gi 1834199290  842 A----LKQNELEDFQKK 854
Cdd:COG4913    819 AlldrLEEDGLPEYEER 835
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1487-1676 9.43e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1487 ELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtskLAEQLSQLKQANEELQKSLQQKQ 1566
Cdd:COG3883     20 AKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1567 -------------------------LLLEKGNEFDTQ-LAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDA 1620
Cdd:COG3883     97 rsggsvsyldvllgsesfsdfldrlSALSKIADADADlLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1621 QKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLA 1676
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1151-1542 9.46e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 47.26  E-value: 9.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1151 GERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANA 1230
Cdd:COG5185    177 KKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLE 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1231 NISATNAELSTVLEVLQAEKSE-----TNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQldeRQKKFEELEEKLKQ 1305
Cdd:COG5185    257 KLVEQNTDLRLEKLGENAESSKrlnenANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA---AAEAEQELEESKRE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1306 AQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNlEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKET-Q 1384
Cdd:COG5185    334 TETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKS-SEELDSFKDTIESTKESLDEIPQNQRGYAQEILATlE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1385 DQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLeeklqaatSQLDAQQATNKELQELLVKSQENE 1464
Cdd:COG5185    413 DTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEE--------SQSRLEEAYDEINRSVRSKKEDLN 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1465 GNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTV--LESQKKSHNEIQDKLEQAQQKERTLQEETS 1542
Cdd:COG5185    485 EELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRArgYAHILALENLIPASELIQASNAKTDGQAAN 564
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 1726-1743 1.01e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.91  E-value: 1.01e-04
                           10
                   ....*....|....*...
gi 1834199290 1726 RLFCDICDEFDqHDTEDC 1743
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 852-1094 1.18e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  852 QKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQktlgHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 931
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  932 SESALKVVQVQLEQLQQQAAASGEegsktvaklHDEISQLKSQAEETQSE--LKSTQSNLEAKSKQLEAANGSLEEEAKK 1009
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGR---------QPPLALLLSPEDFLDAVrrLQYLKYLAPARREQAEELRADLAELAAL 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1010 SGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTlhAELQAERS 1089
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE--AAAAAERT 243


                   ....*
gi 1834199290 1090 SSSAL 1094
Cdd:COG4942    244 PAAGF 248
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 900-1630 1.19e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 47.12  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  900 LQAALEELKKEKETIIKekeqELQQLQSKSAESESALKVVQVQLEQLQQQAAAsgEEGSKtvaklhdeISQLKSQAEETQ 979
Cdd:pfam10174    1 LQAQLRDLQRENELLRR----ELDIKESKLGSSMNSIKTFWSPELKKERALRK--EEAAR--------ISVLKEQYRVTQ 66

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  980 SELKSTQSNLEAKSKQLEAA---NGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHtdvESKTKQLEAANAALEKVN 1056
Cdd:pfam10174   67 EENQHLQLTIQALQDELRAQrdlNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEH---ERQAKELFLLRKTLEEME 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1057 KEYAESRAEASDLQDKVKEITDTLHaelqaerssSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQ 1136
Cdd:pfam10174  144 LRIETQKQTLGARDESIKKLLEMLQ---------SKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREE 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1137 ---LQDSQDSQTKLKA------EGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKM 1207
Cdd:pfam10174  215 lhrRNQLQPDPAKTKAlqtvieMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQL 294

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1208 ASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNhifeLFEMEADMNSERLIEKVTgikeelkethl 1287
Cdd:pfam10174  295 KQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA----ILQTEVDALRLRLEEKES----------- 359

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1288 QLDERQKKFEELEEKlKQAQQSE-QKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVR---ESSSIIEAQN 1363
Cdd:pfam10174  360 FLNKKTKQLQDLTEE-KSTLAGEiRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKslqTDSSNTDTAL 438

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1364 TKLNESNVQLENKTSCLKETQDQL-------LESQKKE-KQLQEEAAKLSGELQQ-------VQEANGDIKDSLVKVEEL 1428
Cdd:pfam10174  439 TTLEEALSEKERIIERLKEQREREdrerleeLESLKKEnKDLKEKVSALQPELTEkesslidLKEHASSLASSGLKKDSK 518

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1429 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEgnlqgeslAVTEKLQQLEQANGELKE--ALCQKE-----NGLKE 1501
Cdd:pfam10174  519 LKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNP--------EINDRIRLLEQEVARYKEesGKAQAEverllGILRE 590

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1502 LQG-KLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLllekgnefDTQLA 1580
Cdd:pfam10174  591 VENeKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQL--------EELMG 662

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1581 EYQKVIDEMDDAASVKSALLEQLQNRVAELeTALRQANDAQKTAYLETKE 1630
Cdd:pfam10174  663 ALEKTRQELDATKARLSSTQQSLAEKDGHL-TNLRAERRKQLEEILEMKQ 711
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
1263-1490 1.21e-04

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 46.06  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1263 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKE 1342
Cdd:COG1340     19 ELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNELREELDELR 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1343 ELVQNLEEKVRESSSIIEA--------QNTKLN-ESNVQLENKTSCLKEtqdqLLESQKKEKQLQEEAAKLSGELQQVQE 1413
Cdd:COG1340     99 KELAELNKAGGSIDKLRKEierlewrqQTEVLSpEEEKELVEKIKELEK----ELEKAKKALEKNEKLKELRAELKELRK 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1414 ANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1490
Cdd:COG1340    175 EAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRK 251
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
787-990 1.23e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  787 QSKEQAAKTLndkEQLEKQISDLK-QLAEQEKLVRE-MTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQE 864
Cdd:COG3206    168 LRREEARKAL---EFLEEQLPELRkELEEAEAALEEfRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  865 IKAQNTQKDFELVESGES---------LKKLQQQLEQKTL----GHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAE 931
Cdd:COG3206    245 LRAQLGSGPDALPELLQSpviqqlraqLAELEAELAELSArytpNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEA 324

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290  932 SESALKVVQVQLEQLQQQaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLE 990
Cdd:COG3206    325 LQAREASLQAQLAQLEAR--------LAELPELEAELRRLEREVEVARELYESLLQRLE 375
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1319-1636 1.33e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1319 TSKEKLTEIQQSLQELQdsvkqkeeLVQnLEEKVRESSSiieAQNTKLNESNVQLENKTSCLKetqdQLLESQKKEKQLQ 1398
Cdd:PRK05771    13 TLKSYKDEVLEALHELG--------VVH-IEDLKEELSN---ERLRKLRSLLTKLSEALDKLR----SYLPKLNPLREEK 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1399 EEAAKLSGElqqvqEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ-----ELLVKSQENEGNLQGESLA 1473
Cdd:PRK05771    77 KKVSVKSLE-----ELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEpwgnfDLDLSLLLGFKYVSVFVGT 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1474 VTEKLQQLEQANGELKEALCQKENGLKE------LQGKLDESNTVLESQKKSHNEIQDkleqaqqkERTLQEETSKLAEQ 1547
Cdd:PRK05771   152 VPEDKLEELKLESDVENVEYISTDKGYVyvvvvvLKELSDEVEEELKKLGFERLELEE--------EGTPSELIREIKEE 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1548 LSQLKQANEELQKSLqqkqlllekgNEFDTQLAEYQKVIDEMDDAASVKSALLEQL--------------QNRVAELETA 1613
Cdd:PRK05771   224 LEEIEKERESLLEEL----------KELAKKYLEELLALYEYLEIELERAEALSKFlktdktfaiegwvpEDRVKKLKEL 293

                          330       340
                   ....*....|....*....|...
gi 1834199290 1614 LRQANDaqKTAYLETKELRRQLE 1636
Cdd:PRK05771   294 IDKATG--GSAYVEFVEPDEEEE 314
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1149-1343 1.35e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 1.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1149 AEGERKEKSFEESIKNLQEEVTKAKTENLELstgtQTTIKDLQERLEITNAELQHKEKmasEDAQKIADLKTLVEAIQVA 1228
Cdd:COG3883     26 SELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALQAEIDKLQAEIAEAEA---EIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1229 NANISATNAelstvleVLQAEK-SETNHIFELFEMEADMNSErLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1307
Cdd:COG3883     99 GGSVSYLDV-------LLGSESfSDFLDRLSALSKIADADAD-LLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1834199290 1308 QSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEE 1343
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1321-1581 1.37e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 46.61  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1321 KEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSsIIEAQNTKLNESNvqlenktscLKETQDQLLESqkkEKQLQEE 1400
Cdd:COG0497    154 EELLEEYREAYRAWRALKKELEELRADEAERARELD-LLRFQLEELEAAA---------LQPGEEEELEE---ERRRLSN 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1401 AAKLSGELQQVQEAngdIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVT---EK 1477
Cdd:COG0497    221 AEKLREALQEALEA---LSGGEGGALDLLGQALRALERLAEYDPSLAELAERLESALIELEEAASELRRYLDSLEfdpER 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1478 LQQLEQANGELKeALCQKENG--------LKELQGKLDEsntvLESqkkshneIQDKLEQAQQKERTLQEETSKLAEQLS 1549
Cdd:COG0497    298 LEEVEERLALLR-RLARKYGVtveellayAEELRAELAE----LEN-------SDERLEELEAELAEAEAELLEAAEKLS 365

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1834199290 1550 QL-KQANEELQKSLQQ--KQLLLEKGnEFDTQLAE 1581
Cdd:COG0497    366 AArKKAAKKLEKAVTAelADLGMPNA-RFEVEVTP 399
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
590-977 1.53e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  590 ALQEEIAKLQEKmtIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLK 669
Cdd:COG4717    106 ELEAELEELREE--LEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELL 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  670 EENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEvrmrdEQIRELNQQLDEVTTQ 749
Cdd:COG4717    184 EQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-----ERLKEARLLLLIAAAL 258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  750 LNVQKADSSALDDMLRLQK--------------EGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEK-QISDLKQLAE 814
Cdd:COG4717    259 LALLGLGGSLLSLILTIAGvlflvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLAAlGLPPDLSPEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  815 QEKLVREMTEnaINQIQLEKESIEQQLALKQNELE---DFQKKQSESEVHLQEiKAQNTQKDFELVesgESLKKLQQQLE 891
Cdd:COG4717    339 LLELLDRIEE--LQELLREAEELEEELQLEELEQEiaaLLAEAGVEDEEELRA-ALEQAEEYQELK---EELEELEEQLE 412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  892 QKTLGHEKLQAAL--EELKKEKETI---IKEKEQELQQLQSKSAESESALKVVqvqleqlqqqaaasgeEGSKTVAKLHD 966
Cdd:COG4717    413 ELLGELEELLEALdeEELEEELEELeeeLEELEEELEELREELAELEAELEQL----------------EEDGELAELLQ 476

                          410
                   ....*....|.
gi 1834199290  967 EISQLKSQAEE 977
Cdd:COG4717    477 ELEELKAELRE 487
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1019-1390 1.55e-04

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 46.39  E-value: 1.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1019 KLKSEVGETQAALsschTDVESKTKQLeaaNAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKL 1098
Cdd:pfam06160   83 KAKKALDEIEELL----DDIEEDIKQI---LEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSYGPAIDELEKQL 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1099 SKFSDEIATgHKELTSKAD-AWSQEMLQK-EKELQELRQQLQDSQDSQTKLK----------AEGERK---------EKS 1157
Cdd:pfam06160  156 AEIEEEFSQ-FEELTESGDyLEAREVLEKlEEETDALEELMEDIPPLYEELKtelpdqleelKEGYREmeeegyaleHLN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1158 FEESIKNLQEEV--TKAKTENLELsTGTQTTIKDLQERLEiTNAELQHKEKMASEDAQKiaDLKTLVEAIQVANANISAT 1235
Cdd:pfam06160  235 VDKEIQQLEEQLeeNLALLENLEL-DEAEEALEEIEERID-QLYDLLEKEVDAKKYVEK--NLPEIEDYLEHAEEQNKEL 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1236 NAELSTVLE--VLQAEKSETNHIFE--LFEMEADMNS--ERLIEKV---TGIKEELKETHLQLDERQKKFEELEEKLKQA 1306
Cdd:pfam06160  311 KEELERVQQsyTLNENELERVRGLEkqLEELEKRYDEivERLEEKEvaySELQEELEEILEQLEEIEEEQEEFKESLQSL 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1307 QQSEQKLQQESQTSKEKLTEIQQSL---------QELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENkt 1377
Cdd:pfam06160  391 RKDELEAREKLDEFKLELREIKRLVeksnlpglpESYLDYFFDVSDEIEDLADELNEVPLNMDEVNRLLDEAQDDVDT-- 468

                          410
                   ....*....|...
gi 1834199290 1378 scLKETQDQLLES 1390
Cdd:pfam06160  469 --LYEKTEELIDN 479
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 800-1077 1.68e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 46.58  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  800 EQLEKQisdLKQLAEQEKLVREMTENAINQIQLEKESIEQQLalKQNELEDF----QKKQSESEVHLQEIKAQNTQKDFE 875
Cdd:PTZ00108  1002 GKLERE---LARLSNKVRFIKHVINGELVITNAKKKDLVKEL--KKLGYVRFkdiiKKKSEKITAEEEEGAEEDDEADDE 1076

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  876 LVESG--------------------ESLKKLQQQLEQKTLGHEKLQAA------LEELKKEKETIIKEKEQE----LQQL 925
Cdd:PTZ00108  1077 DDEEElgaavsydyllsmpiwsltkEKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEekeiAKEQ 1156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  926 QSKSAESESALKVVQ-VQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLE 1004
Cdd:PTZ00108  1157 RLKSKTKGKASKLRKpKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPK 1236

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290 1005 EEAKKSGHLLEQITKLKSEVGETQaalSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEIT 1077
Cdd:PTZ00108  1237 KSSVKRLKSKKNNSSKSSEDNDEF---SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPT 1306
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1345-1652 1.69e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1345 VQNLEEKVRESSSIIEAQNTKLNESNVQLENKTScLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEA---------- 1414
Cdd:COG3096    274 MRHANERRELSERALELRRELFGARRQLAEEQYR-LVEMARELEELSARESDLEQDYQAASDHLNLVQTAlrqqekiery 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1415 NGDIKDSLVKVEELVKVLE---EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQAngelkEA 1491
Cdd:COG3096    353 QEDLEELTERLEEQEEVVEeaaEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKA-----RA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1492 LCQK--------ENGLKELQGKLDE-SNTVLESQKK------SHNEIQDKLE------------QAQQKERTLQE---ET 1541
Cdd:COG3096    428 LCGLpdltpenaEDYLAAFRAKEQQaTEEVLELEQKlsvadaARRQFEKAYElvckiageversQAWQTARELLRryrSQ 507

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1542 SKLAEQLSQLKQANEELQKSLQQKQlllekgnEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQ 1621
Cdd:COG3096    508 QALAQRLQQLRAQLAELEQRLRQQQ-------NAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1834199290 1622 KTAYLETKELRRQLESLElekSREVLSLKAQ 1652
Cdd:COG3096    581 SELRQQLEQLRARIKELA---ARAPAWLAAQ 608
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 1200-1672 1.89e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 46.35  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1200 ELQHKEKMASEDAQKIADLKTLVEAIQvananisATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIK 1279
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQ-------EENQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1280 EELKETHLQLDERQKKFEELEekLKQAQQSEQKLQQESQtsKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSII 1359
Cdd:pfam10174  113 LTEENFRRLQSEHERQAKELF--LLRKTLEEMELRIETQ--KQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIA 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1360 EAQnTKLNESNVQLENKTsclKETQdQLLESQKKEKQLQEEAAKLSGeLQQVQEAN----GDIKDSLVKVEELVKVLE-- 1433
Cdd:pfam10174  189 EAE-MQLGHLEVLLDQKE---KENI-HLREELHRRNQLQPDPAKTKA-LQTVIEMKdtkiSSLERNIRDLEDEVQMLKtn 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1434 -----EKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGE-------LKEALCQKENGLKE 1501
Cdd:pfam10174  263 gllhtEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDckqhievLKESLTAKEQRAAI 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1502 LQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQkqlLLEKGNEFDTQLAE 1581
Cdd:pfam10174  343 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIEN---LQEQLRDKDKQLAG 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1582 YQKVIDE--------------MDDAASVKSALLEQLQNRVAELETALRQANDAQKTaylETKELRRQLESLE---LEKSR 1644
Cdd:pfam10174  420 LKERVKSlqtdssntdtalttLEEALSEKERIIERLKEQREREDRERLEELESLKK---ENKDLKEKVSALQpelTEKES 496

                          490       500
                   ....*....|....*....|....*....
gi 1834199290 1645 EVLSLKAQMNGASSRSGKGD-EVESLDIE 1672
Cdd:pfam10174  497 SLIDLKEHASSLASSGLKKDsKLKSLEIA 525
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1071-1571 1.90e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.43  E-value: 1.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1071 DKVKEITDtlhaELQAERSSSSALHTKLSKFSDEIATGHKELTSkaDAWSQEMLQKEKElqELRQQLQDSQDSQTKLKAE 1150
Cdd:PRK01156   169 DKLKDVID----MLRAEISNIDYLEEKLKSSNLELENIKKQIAD--DEKSHSITLKEIE--RLSIEYNNAMDDYNNLKSA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1151 GERKeKSFEESIKNLQEEVTKAKTEnLELSTGTQTTIKDLQERL-EITNAELQHKEKMASEDAQKIADLKTLVEAIQVAN 1229
Cdd:PRK01156   241 LNEL-SSLEDMKNRYESEIKTAESD-LSMELEKNNYYKELEERHmKIINDPVYKNRNYINDYFKYKNDIENKKQILSNID 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1230 ANISATNAELSTvLEVLQAEKSE-----------TNHIFELFEMEADMNS-----ERLIEKV-----------TGIKEEL 1282
Cdd:PRK01156   319 AEINKYHAIIKK-LSVLQKDYNDyikkksryddlNNQILELEGYEMDYNSylksiESLKKKIeeyskniermsAFISEIL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1283 KETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQEL------------------QDSVKQKEEL 1344
Cdd:PRK01156   398 KIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttlgeeksNHIINHYNEK 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1345 VQNLEEKVREsssiIEAQNTKLNESNVQLENKTSCLK-------ETQDQLLESQKKE-KQLQEEAAKLSGELQQVQEANG 1416
Cdd:PRK01156   478 KSRLEEKIRE----IEIEVKDIDEKIVDLKKRKEYLEseeinksINEYNKIESARADlEDIKIKINELKDKHDKYEEIKN 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1417 DIKDslVKVEELVKVLEE--KLQAATSQLDAQ------QATNKELQELLVKSQENEGNLQGESLAVTEKLQQLE------ 1482
Cdd:PRK01156   554 RYKS--LKLEDLDSKRTSwlNALAVISLIDIEtnrsrsNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIEneannl 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1483 -------QANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1555
Cdd:PRK01156   632 nnkyneiQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                          570
                   ....*....|....*.
gi 1834199290 1556 EELQKSLQQKQLLLEK 1571
Cdd:PRK01156   712 NELSDRINDINETLES 727
COG5022 COG5022
Myosin heavy chain [General function prediction only];
684-1004 2.05e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.61  E-value: 2.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  684 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEIL---QTEVRMRDEQIRELNQQLDEVTTQLNVQKAD---- 756
Cdd:COG5022    829 EKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYlqsAQRVELAERQLQELKIDVKSISSLKLVNLELesei 908

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  757 ---SSALDDMLRLQKEGTEEKSTLLEKTEKElVQSKEQAAKTLNDKEQLEK---QISDLKQLAEQEKLVREMTENAINQI 830
Cdd:COG5022    909 ielKKSLSSDLIENLEFKTELIARLKKLLNN-IDLEEGPSIEYVKLPELNKlheVESKLKETSEEYEDLLKKSTILVREG 987

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  831 QLEKESIE---QQLALKQNELEDFQKKQSESEVHLQEI--KAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALE 905
Cdd:COG5022    988 NKANSELKnfkKELAELSKQYGALQESTKQLKELPVEVaeLQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYK 1067

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  906 ELKKEKETIIKEKEQELQQLQSKSAESESALKvvqvqleqlqqQAAASGEEGSKTVAKLHDEISQLKSQAEETQSE--LK 983
Cdd:COG5022   1068 ALKLRRENSLLDDKQLYQLESTENLLKTINVK-----------DLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISkfLS 1136

                          330       340
                   ....*....|....*....|.
gi 1834199290  984 STQSNLEAKSKQLEAANGSLE 1004
Cdd:COG5022   1137 QLVNTLEPVFQKLSVLQLELD 1157
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 776-1011 2.25e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  776 TLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDF---Q 852
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERaraL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  853 KKQSESEVHLQEIKAQNTQKDFelVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAES 932
Cdd:COG3883     96 YRSGGSVSYLDVLLGSESFSDF--LDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290  933 ESALKVVQVQLEQLqqqaaasgeegSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSG 1011
Cdd:COG3883    174 EAQQAEQEALLAQL-----------SAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 241
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1439-1624 2.25e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1439 ATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKK 1518
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1519 S----------------HNEIQDKLEQAQQKERtLQEETSKLAEQLSQLKQANEELQKSLQQKQlllekgNEFDTQLAEY 1582
Cdd:COG3883     94 AlyrsggsvsyldvllgSESFSDFLDRLSALSK-IADADADLLEELKADKAELEAKKAELEAKL------AELEALKAEL 166

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1583 QKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1624
Cdd:COG3883    167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAA 208
PRK11637 PRK11637
AmiB activator; Provisional
 1320-1556 2.46e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.45  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1320 SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKlnesnvqlenktscLKETQDQLLESQKKEKQLQE 1399
Cdd:PRK11637    45 NRDQLKSIQQDIAAKEKSVRQQQQQRASLLAQLKKQEEAISQASRK--------------LRETQNTLNQLNKQIDELNA 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1400 EAAKLsgELQQVQeangdikdslvkveelvkvlEEKLQAAtsQLDA--QQATNKELQELLvksqENEGNLQGESL----- 1472
Cdd:PRK11637   111 SIAKL--EQQQAA--------------------QERLLAA--QLDAafRQGEHTGLQLIL----SGEESQRGERIlayfg 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1473 ----AVTEKLQQLEQANGELKEalcQKenglKELQGKLDESNTVLESQKKShneiQDKLEQAQQ-KERTLQEETSKLAE- 1546
Cdd:PRK11637   163 ylnqARQETIAELKQTREELAA---QK----AELEEKQSQQKTLLYEQQAQ----QQKLEQARNeRKKTLTGLESSLQKd 231

                          250
                   ....*....|..
gi 1834199290 1547 --QLSQLKQaNE 1556
Cdd:PRK11637   232 qqQLSELRA-NE 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
718-917 2.63e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 2.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  718 KTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKA---DSSALDDMLRLQKEgteekstlLEKTEKELvqskEQAAK 794
Cdd:COG4913    615 LEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeYSWDEIDVASAERE--------IAELEAEL----ERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  795 TLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF 874
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEE-------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1834199290  875 ELVESGESLKKLQQQLEQKTlghEKLQAALEELKKEKETIIKE 917
Cdd:COG4913    756 AAALGDAVERELRENLEERI---DALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
684-933 2.70e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 2.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  684 TRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQT---------EVRMRDEQIRELNQQLDEVTtqlnvqk 754
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELEAELERLD------- 681

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  755 ADSSALDdmlRLQKEgteekstlLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI---- 830
Cdd:COG4913    682 ASSDDLA---ALEEQ--------LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElral 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  831 ------QLEKESIEQQLALK-QNELEDFQKKQSESEVHLQEIKAQ-NTQKDFELVESGESLKKLQQQLEQktlgHEKLQA 902
Cdd:COG4913    751 leerfaAALGDAVERELRENlEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESLPEYLAL----LDRLEE 826

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1834199290  903 -ALEELKKE-KETIIKEKEQELQQLQSKSAESE 933
Cdd:COG4913    827 dGLPEYEERfKELLNENSIEFVADLLSKLRRAI 859
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 703-1609 2.78e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 45.98  E-value: 2.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  703 NLKATSDSLESERVNKTDECEILqtevRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEkstllEKTE 782
Cdd:PTZ00440   881 IIKTLNIAINRSNSNKQLVEHLL----NNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLNNLNKEKEKIEK-----QLSD 951

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  783 KELVQSKEQAAKTLNDKEQLEKQISDlKQLAEQEKLVREMTENAINQIQLEKESIEQQLAlkQNELEDFQKKQSESEVHL 862
Cdd:PTZ00440   952 TKINNLKMQIEKTLEYYDKSKENING-NDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNIL--NKKIDDLIKKQHDDIIEL 1028

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  863 ---------QEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETI---IKEKEQELQQLQSKSA 930
Cdd:PTZ00440  1029 idklikekgKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALlkkIDENKNKLIEIKNKSH 1108

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  931 ESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEisqLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKS 1010
Cdd:PTZ00440  1109 EHVVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKE---LENMNLEDITLNEVNEIEIEYERILIDHIVEQINNEAKKS 1185

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1011 GHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAL---EKVNKEYAESR-----AEASDLQDKVKEITDTLHA 1082
Cdd:PTZ00440  1186 KTIMEEIESYKKDIDQVKKNMSKERNDHLTTFEYNAYYDKATasyENIEELTTEAKglkgeANRSTNVDELKEIKLQVFS 1265

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1083 ELQAERSSSSALHTKLSkfsdEIATGHKELTS-KADAWSQEMLQKEKELQELrqqlqdsqdsqtKLKAEGERKEKSfeES 1161
Cdd:PTZ00440  1266 YLQQVIKENNKMENALH----EIKNMYEFLISiDSEKILKEILNSTKKAEEF------------SNDAKKELEKTD--NL 1327

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1162 IKNLQEEVTKAKTENLELSTgtqtTIKDLQERLEITNAELQHKEKMASEDA-----QKIADLKTLVEaIQVANANISATN 1236
Cdd:PTZ00440  1328 IKQVEAKIEQAKEHKNKIYG----SLEDKQIDDEIKKIEQIKEEISNKRKEinkylSNIKSNKEKCD-LHVRNASRGKDK 1402

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1237 AELSTVLEVLQAEKSETNHIFELFEMeadmnserlIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQE 1316
Cdd:PTZ00440  1403 IDFLNKHEAIEPSNSKEVNIIKITDN---------INKCKQYSNEAMETENKADENNDSIIKYEKEITNILNNSSILGKK 1473

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1317 SQTSKEK------LTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLES 1390
Cdd:PTZ00440  1474 TKLEKKKkeatniMDDINGEHSIIKTKLTKSSEKLNQLNEQPNIKREGDVLNNDKSTIAYETIQYNLGRVKHNLLNILNI 1553

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1391 QKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVK------VEELVKVLEEK--LQAATSQLDAQQATNKELQELLVKSQE 1462
Cdd:PTZ00440  1554 KDEIETILNKAQDLMRDISKISKIVENKNLENLNdkeadyVKYLDNILKEKqlMEAEYKKLNEIYSDVDNIEKELKKHKK 1633

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1463 N--EGNLQgeslAVTEKLQQLEQANGELKEALCQKENGLKELQGKLD----ESNTVLESQKKSHNEIQDKLEQAQQKERT 1536
Cdd:PTZ00440  1634 NyeIGLLE----KVIEINKNIKLYMDSTKESLNSLVNNFSSLFNNFYlnkyNINENLEKYKKKLNEIYNEFMESYNIIQE 1709

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1834199290 1537 LQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF--DTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAE 1609
Cdd:PTZ00440  1710 KMKEVSNDDVDYNEAKTLREEAQKEEVNLNNKEEEAKKYlnDIKKQESFRFILYMKEKLDELSKMCKQQYNIVDE 1784
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1534-1703 3.01e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1534 ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLL---EKGNEFDTQLAEYQkVIDEMDDAASV--KSALLEQLQNRVA 1608
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpirELAERYAAARERLA-ELEYLRAALRLwfAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1609 ELETALRQANDAQKtayletkELRRQLESLEleksREVLSLKAQMNGASsrsgkGDEVESLDietslAKINFLNSIIADM 1688
Cdd:COG4913    299 ELRAELARLEAELE-------RLEARLDALR----EELDELEAQIRGNG-----GDRLEQLE-----REIERLERELEER 357

                          170
                   ....*....|....*
gi 1834199290 1689 QQKNDALKAKVQTLE 1703
Cdd:COG4913    358 ERRRARLEALLAALG 372
46 PHA02562
endonuclease subunit; Provisional
 1321-1568 4.20e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 4.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1321 KEKLTEIQQSLQEL---QDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQL-ENKTSCLKETQDQLLEsqkkekq 1396
Cdd:PHA02562   173 KDKIRELNQQIQTLdmkIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEaKTIKAEIEELTDELLN------- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1397 LQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEE--KLQAATSQLDaqqatnkELQELLVKSQENEGNLQGESLAV 1474
Cdd:PHA02562   246 LVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQIS-------EGPDRITKIKDKLKELQHSLEKL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1475 TEKLQQLEQANGELKEAlcQKEngLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQA 1554
Cdd:PHA02562   319 DTAIDELEEIMDEFNEQ--SKK--LLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394

                          250
                   ....*....|....
gi 1834199290 1555 NEELQKSLQQKQLL 1568
Cdd:PHA02562   395 KSELVKEKYHRGIV 408
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1268-1490 4.21e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.20  E-value: 4.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1268 SERLIEKVtgiKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQElqdsvkQKEELVQN 1347
Cdd:PRK00409   500 PENIIEEA---KKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQE------EEDKLLEE 570

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1348 LEEKVREsssIIEAqntklnesnvqlenktscLKETQDQLLesqkKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEE 1427
Cdd:PRK00409   571 AEKEAQQ---AIKE------------------AKKEADEII----KELRQLQKGGYASVKAHELIEARKRLNKANEKKEK 625

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290 1428 LVKVleeklqaatsqldaQQATNKELQ--------------ELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKE 1490
Cdd:PRK00409   626 KKKK--------------QKEKQEELKvgdevkylslgqkgEVLSIPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKK 688
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
734-1335 4.25e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  734 EQIRELNQQLDEVTTQLNVQKAdssaLDDMLRLQKEgtEEKSTLLEKtekELVQSKEQAAKTLNDKEQLEKQISDLKQLA 813
Cdd:COG4913    255 EPIRELAERYAAARERLAELEY----LRAALRLWFA--QRRLELLEA---ELEELRAELARLEAELERLEARLDALREEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  814 EQeklvremTENAINQIQLE-KESIEQQLALKQNELEDFQKKQSESEVHLQEIkaqntqkDFELVESGESLKKLQQQLEQ 892
Cdd:COG4913    326 DE-------LEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAAL-------GLPLPASAEEFAALRAEAAA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  893 KTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAlkvvqvqleqlqqqaaasgeeGSKTVAKLHDEISQLK 972
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR---------------------KSNIPARLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  973 SQAEETQSELK------------------------STQSNLEAKSKQLEAANGSLE----------EEAKKSGHLLEQIT 1018
Cdd:COG4913    451 EALGLDEAELPfvgelievrpeeerwrgaiervlgGFALTLLVPPEHYAAALRWVNrlhlrgrlvyERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1019 --------KLKSEVGETQAALSS---------CHTDVE--------------------------------------SKTK 1043
Cdd:COG4913    531 ldpdslagKLDFKPHPFRAWLEAelgrrfdyvCVDSPEelrrhpraitragqvkgngtrhekddrrrirsryvlgfDNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1044 QLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSS-----ALHTKLSKFSDEIAtghkeltsKADA 1118
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDeidvaSAEREIAELEAELE--------RLDA 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1119 WSQEMLQKEKELQELRQQLQDSQDSQTKLKaegeRKEKSFEESIKNLQEEVTKAKTENLEL-STGTQTTIKDLQERLEIT 1197
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELK----GEIGRLEKELEQAEEELDELQDRLEAAeDLARLELRALLEERFAAA 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1198 NAELQHKEKMASedaqkiadlktLVEAIQVANANISATNAELSTVLEVLQAEksetnHIFELFEMEADMNSerlIEKVTG 1277
Cdd:COG4913    759 LGDAVERELREN-----------LEERIDALRARLNRAEEELERAMRAFNRE-----WPAETADLDADLES---LPEYLA 819

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1278 IKEELKETHLQldERQKKFEELEEKLKQAQQSE--QKLQQESQTSKEKLTEIQQSLQELQ 1335
Cdd:COG4913    820 LLDRLEEDGLP--EYEERFKELLNENSIEFVADllSKLRRAIREIKERIDPLNDSLKRIP 877
COG4487 COG4487
Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];
773-933 4.47e-04

Uncharacterized conserved protein, contains DUF2130 domain [Function unknown];


Pssm-ID: 443580 [Multi-domain]  Cd Length: 425  Bit Score: 44.94  E-value: 4.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  773 EKSTLLEKTEKELVQSKEQAAKTLNDK-EQLEKQISDLKQ-----LAEQEKLVREMTENAINQIQLEKESIEQQLA-LKQ 845
Cdd:COG4487     37 ERLADAAKREAALELAEAKAKAQLQEQvAEKDAEIAELRArleaeERKKALAVAEEKEKELAALQEALAEKDAKLAeLQA 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  846 NELEdFQKKQSESEVHLQEIKAQnTQKdfELVESGESLK-KLQQQLEQKTLGHEKLQAA-----LEELKKEKETIIKEKE 919
Cdd:COG4487    117 KELE-LLKKERELEDAKREAELT-VEK--ERDEELDELKeKLKKEEEEKQLAEKSLKVAeyekqLKDMQEQIEELKRKKE 192

                          170
                   ....*....|....
gi 1834199290  920 QELQQLQSKSAESE 933
Cdd:COG4487    193 QGSTQLQGEVLELE 206
ClyA-like cd21116
family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including ...
 1302-1450 4.63e-04

family of the cytolysin A (ClyA) family alpha pore-forming toxins (alpha-PFT) including Bacillus cereus HblB, Aeromonas hydrophila AhlB, Bacillus thuringiensis Cry6Aa and similar proteins; This family belongs to the ClyA family of alpha-PFT bacterial toxins. PFTs form the major group of virulence factors in many pathogenic bacteria and in general are critical components of the molecular offensive and defensive machinery of cells in all kingdoms of life. Bacterial PFTs facilitate the takeover of host resources by puncturing holes in the membrane. PFTs can be classified as alpha-PFTs and beta-PFTs depending on the secondary structures of their membrane component. Alpha-PFTs use a ring of amphipathic helices while beta-PFTs use a beta-barrel to construct the pore. Members of this family include the toxins: Bacillus cereus hemolysin binding component B (HblB or HBL-B) of the diarrheal enterotoxin hemolysin BL, Aeromonas hydrophila hemolytic (Ahl) component B (AhlB) of the tripartite AhlABC toxin, Vibrio cholerae cytotoxin motility associated killing factor A (MakA) cytotoxin, Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA), Bacillus thuringiensis crystal 6Aa (Cry6Aa) parasporal crystal (Cry) toxin, and Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA) of the non-hemolytic enterotoxin Nhe, which, despite its name, is hemolytic, among others. In solution, ClyA proteins have an elongated, almost entirely alpha-helical structure, except for a short hydrophobic beta-hairpin known as the beta-tongue. Pore formation by ClyA requires circular oligomerization of the toxin by a sequential mechanism. This, in turn, concentrates the amphipathic helices in the center of the ring-like structure, forming a helical barrel that inserts into the membrane by a wedge-like mechanism. Compared with ClyA, NheA is almost entirely alpha-helical with an enlarged "head" domain, and an enlarged beta-tongue; it has been proposed that NheA could even form beta-barrel pores. Alpha-PFTs with similar structures are increasingly being found in eukaryotes, in particular as components of the immune systems of animals. This family may be distantly related to Escherichia coli alpha-PFT hemolysin E (HlyE, also known as ClyA or SheA).


Pssm-ID: 439149 [Multi-domain]  Cd Length: 224  Bit Score: 43.56  E-value: 4.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1302 KLKQAQQSEQKLQQESQTSKEKLteiQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLK 1381
Cdd:cd21116     74 YYPDLIELADNLIKGDQGAKQQL---LQGLEALQSQVTKKQTSVTSFINELTTFKNDLDDDSRNLQTDATKAQAQVAVLN 150

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290 1382 ETQDQLlesqkkeKQLQEEAAKLSGELQQVQEANGDIKDSLvkveelvKVLEEKLQAATSQLDAQQATN 1450
Cdd:cd21116    151 ALKNQL-------NSLAEQIDAAIDALEKLSNDWQTLDSDI-------KELITDLEDAESSIDAAFLQA 205
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 736-1116 4.68e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 45.00  E-value: 4.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  736 IRELNQQLDEVTTQLNVqkadsSALDDMLRLQKEGTEEKSTLLEKTEKELvqSKEQAAKTLNDKEQLEKQISDL-KQLAE 814
Cdd:NF033838    71 LSEIQKSLDKRKHTQNV-----ALNKKLSDIKTEYLYELNVLKEKSEAEL--TSKTKKELDAAFEQFKKDTLEPgKKVAE 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  815 QEKLVREMTENAINQIQlEKESIEQQLALKQNELE--DFQKKQSESEVHLQEIKAQNTQKDfelvesgESLKKLQQQLEQ 892
Cdd:NF033838   144 ATKKVEEAEKKAKDQKE-EDRRNYPTNTYKTLELEiaESDVEVKKAELELVKEEAKEPRDE-------EKIKQAKAKVES 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  893 KtlgheklQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLK 972
Cdd:NF033838   216 K-------KAEATRLEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSDS 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  973 SQAEET--QSELKSTQSNLEAKSKQLEAangslEEEAKksghlleqitKLKSEVGETQAALSSCHTDVESKTKQLEAANA 1050
Cdd:NF033838   289 SVGEETlpSPSLKPEKKVAEAEKKVEEA-----KKKAK----------DQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1051 ALEKVNKEYAESRAEasdlqDKVKEItdtlhaelQAERSSSSALHTKLSKFSDEIATGHKELTSKA 1116
Cdd:NF033838   354 ELELVKEEAKEPRNE-----EKIKQA--------KAKVESKKAEATRLEKIKTDRKKAEEEAKRKA 406
Rabaptin pfam03528
Rabaptin;
1293-1645 5.47e-04

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 44.71  E-value: 5.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1293 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSlqelqdsvkqKEELVQNLEEKVRESSSIIEAQNTKLNESNVQ 1372
Cdd:pfam03528    7 QQRVAELEKENAEFYRLKQQLEAEFNQKRAKFKELYLA----------KEEDLKRQNAVLQEAQVELDALQNQLALARAE 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1373 LENKTSCLKETQDQLLES-QKKEKQLQEEAAKLSGELqqvqeangdiKDSLVKVEELVKVLEEKLQAATSQL-DAQQATN 1450
Cdd:pfam03528   77 MENIKAVATVSENTKQEAiDEVKSQWQEEVASLQAIM----------KETVREYEVQFHRRLEQERAQWNQYrESAEREI 146

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1451 KELQELLVKSQENEgNLQGESLAVTEKLQQL-------EQANGELKEALCQKENGLKELQG-KLDESNTVLESQKKSHNE 1522
Cdd:pfam03528  147 ADLRRRLSEGQEEE-NLEDEMKKAQEDAEKLrsvvmpmEKEIAALKAKLTEAEDKIKELEAsKMKELNHYLEAEKSCRTD 225

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1523 iqdkleqaqqkertLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAE-YQKVIDEMDDAASVksaLLE 1601
Cdd:pfam03528  226 --------------LEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQHNQLKHtWQKANDQFLESQRL---LMR 288

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1834199290 1602 QLQNRVAELET-ALRQANDAQKTAYLETKELRRQLESLELEKSRE 1645
Cdd:pfam03528  289 DMQRMESVLTSeQLRQVEEIKKKDQEEHKRARTHKEKETLKSDRE 333
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1269-1590 5.82e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.12  E-value: 5.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1269 ERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNL 1348
Cdd:COG4372     48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1349 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEEL 1428
Cdd:COG4372    128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEK 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1429 VKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDE 1508
Cdd:COG4372    208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1509 SNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1588
Cdd:COG4372    288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367


                   ..
gi 1834199290 1589 MD 1590
Cdd:COG4372    368 AD 369
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1326-1553 7.17e-04

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 43.85  E-value: 7.17e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  1326 EIQQ-SLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQlLESQK-----KEKQLQE 1399
Cdd:smart00787   66 ELYQfSCKELKKYISEGRDLFKEIEEETLINNPPLFKEYFSASPDVKLLMDKQFQLVKTFAR-LEAKKmwyewRMKLLEG 144

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  1400 EAAKLSGELQQVQEAngdiKDSLVKVEELVKVLEEKLQaatsqlDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQ 1479
Cdd:smart00787  145 LKEGLDENLEGLKED----YKLLMKELELLNSIKPKLR------DRKDALEEELRQLKQLEDELEDCDPTELDRAKEKLK 214

                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290  1480 QLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTlqeETSKLAEQLSQLKQ 1553
Cdd:smart00787  215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFK---EIEKLKEQLKLLQS 285
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 540-1173 7.24e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 7.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  540 EAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPpDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEE 619
Cdd:TIGR00618  202 RSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHA-YLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  620 EQRLREN--------------VKYLNEQIATLQSELVSKDEALEKFSLSECGIenLRRELELLKEENEKQAQEAQAEFTR 685
Cdd:TIGR00618  281 ETQERINrarkaaplaahikaVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAH--VKQQSSIEEQRRLLQTLHSQEIHIR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  686 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVrmrdEQIRELNQQLDEVTTQLNVQKADSSALDDMLR 765
Cdd:TIGR00618  359 DAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKEL----DILQREQATIDTRTSAFRDLQGQLAHAKKQQE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  766 LQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEK----------- 834
Cdd:TIGR00618  435 LQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPcplcgscihpn 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  835 ----------------ESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHE 898
Cdd:TIGR00618  515 parqdidnpgpltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  899 KLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEET 978
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKEL 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  979 QSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKE 1058
Cdd:TIGR00618  675 LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQART 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1059 YAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQ 1138
Cdd:TIGR00618  755 VLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFL 834

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1834199290 1139 DSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAK 1173
Cdd:TIGR00618  835 SRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQA 869
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1477-1624 8.11e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 8.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1477 KLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQE--ETSKLAEQLSQLKQA 1554
Cdd:COG1579     18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlGNVRNNKEYEALQKE 97

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1555 NEELQKSLQQ-KQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTA 1624
Cdd:COG1579     98 IESLKRRISDlEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1184-1414 9.38e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 9.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1184 QTTIKDLQERLEITNA------ELqhkeKMASEDAQKIAD-LKTLVEA-----IQVANANISATNAELSTVLEVLQAEKS 1251
Cdd:COG3206    117 EAAIERLRKNLTVEPVkgsnviEI----SYTSPDPELAAAvANALAEAyleqnLELRREEARKALEFLEEQLPELRKELE 192

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1252 ETNHIFELFE-----MEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLK--------------------QA 1306
Cdd:COG3206    193 EAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGsgpdalpellqspviqqlraQL 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1307 QQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQ 1386
Cdd:COG3206    273 AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                          250       260
                   ....*....|....*....|....*...
gi 1834199290 1387 LLESQKKEKQLQEEAAKLSGELQQVQEA 1414
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLA 380
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 770-927 9.61e-04

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 43.86  E-value: 9.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  770 GTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQeklvremTENAINQIQLEKESIEQQLALK----- 844
Cdd:pfam05667  322 KVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKKLESSIKQ-------VEEELEELKEQNEELEKQYKVKkktld 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  845 -----QNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKL--------QQQLEQKTLGHEKLQAALEELKKek 911
Cdd:pfam05667  395 llpdaEENIAKLQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAksnkedesQRKLEEIKELREKIKEVAEEAKQ-- 472

                          170
                   ....*....|....*.
gi 1834199290  912 etiikeKEQELQQLQS 927
Cdd:pfam05667  473 ------KEELYKQLVA 482
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1263-1436 1.15e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.60  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1263 EADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEiqqsLQELQDSVKQKE 1342
Cdd:COG1579     14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKK----YEEQLGNVRNNK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1343 ELvQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQvqeangDIKDSL 1422
Cdd:COG1579     90 EY-EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA------ELEELE 162

                          170
                   ....*....|....
gi 1834199290 1423 VKVEELVKVLEEKL 1436
Cdd:COG1579    163 AEREELAAKIPPEL 176
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1395-1703 1.18e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1395 KQLQEEAAKLSGELQQVQEANGDIKDSLVkveELVKVLEEkLQAATSQLDAQ-QATNKELqellvksqenegNLQGESLA 1473
Cdd:COG3096    281 RELSERALELRRELFGARRQLAEEQYRLV---EMARELEE-LSARESDLEQDyQAASDHL------------NLVQTALR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1474 VTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEEtsklAEQLSQLKQ 1553
Cdd:COG3096    345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTR----AIQYQQAVQ 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1554 ANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE-----------MDDAASVKSALLEQLQNRVAELETA--------- 1613
Cdd:COG3096    421 ALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEevleleqklsvADAARRQFEKAYELVCKIAGEVERSqawqtarel 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1614 LRQANDAQKTAYLETkELRRQLESLE--LEKSREVLSLKAQMNGASSRS-GKGDEVESL------DIETSLAKINFLNSI 1684
Cdd:COG3096    501 LRRYRSQQALAQRLQ-QLRAQLAELEqrLRQQQNAERLLEEFCQRIGQQlDAAEELEELlaeleaQLEELEEQAAEAVEQ 579

                          330
                   ....*....|....*....
gi 1834199290 1685 IADMQQKNDALKAKVQTLE 1703
Cdd:COG3096    580 RSELRQQLEQLRARIKELA 598
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 829-1160 1.21e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 43.35  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  829 QIQLEKESIEQQLALKQNEL--EDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEE 906
Cdd:pfam07888   33 QNRLEECLQERAELLQAQEAanRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  907 LKKEKETIIKEKEQELQQLQsksaESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEisqlKSQAEETQSELKSTQ 986
Cdd:pfam07888  113 LSEEKDALLAQRAAHEARIR----ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE----EAERKQLQAKLQQTE 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  987 SNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQ---AALSSCHTDVESKTKQLEAANAALEKVNKEYAEsr 1063
Cdd:pfam07888  185 EELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHrkeAENEALLEELRSLQERLNASERKVEGLGEELSS-- 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1064 aeasdlqdkVKEITDTLHAELQAERSSSSALHTKLSKFSDeiatghkeltskadAWSQEMLQKEKELQELRQQLQDSQDS 1143
Cdd:pfam07888  263 ---------MAAQRDRTQAELHQARLQAAQLTLQLADASL--------------ALREGRARWAQERETLQQSAEADKDR 319

                          330
                   ....*....|....*..
gi 1834199290 1144 QTKLKAEGERKEKSFEE 1160
Cdd:pfam07888  320 IEKLSAELQRLEERLQE 336
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
685-926 1.25e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  685 RKLAEKSVEVLRL--------SSELQNLKATSDSLESERVNKTDeceILQTEVRMRD-EQIRELNQQLDE--VTTQLNVQ 753
Cdd:COG3206     93 RPVLERVVDKLNLdedplgeeASREAAIERLRKNLTVEPVKGSN---VIEISYTSPDpELAAAVANALAEayLEQNLELR 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  754 KADSSALDDMLRLQKEGTEEKstlLEKTEKELV--QSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQI- 830
Cdd:COG3206    170 REEARKALEFLEEQLPELRKE---LEEAEAALEefRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALr 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  831 -QLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG--------HEKLQ 901
Cdd:COG3206    247 aQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRilasleaeLEALQ 326

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1834199290  902 AALEELKKEKETI------IKEKEQELQQLQ 926
Cdd:COG3206    327 AREASLQAQLAQLearlaeLPELEAELRRLE 357
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1217-1362 1.46e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 42.70  E-value: 1.46e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  1217 DLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNH-IFELFEMEADMNSERLIEkVTGIKEELKETHLQLDERQKK 1295
Cdd:smart00787  148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEeLRQLKQLEDELEDCDPTE-LDRAKEKLKKLLQEIMIKVKK 226

                            90       100       110       120       130       140
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1834199290  1296 FEELEEKLkqaqqseQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQ 1362
Cdd:smart00787  227 LEELEEEL-------QELESKIEDLTNKKSELNTEIAEAEKKLEQCRGFTFKEIEKLKEQLKLLQSL 286
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1286-1389 1.46e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1286 HLQLDERQKKFEELEEKLKQAQQSEQKLQQESQT-SKEKLTEIQQSLQELQ---DSVKQKEELVQNLEEKVRESSSIIEA 1361
Cdd:COG0542    403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQDEaSFERLAELRDELAELEeelEALKARWEAEKELIEEIQELKEELEQ 482

                           90       100
                   ....*....|....*....|....*...
gi 1834199290 1362 QNTKLNESNVQLENKTSCLKETQDQLLE 1389
Cdd:COG0542    483 RYGKIPELEKELAELEEELAELAPLLRE 510
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 512-879 1.56e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  512 PLKARIVE-LESALD--NERKKTEElqcSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLvsatpslqsilPPDLPSDD 588
Cdd:PRK10929    41 PAQAEIVEaLQSALNwlEERKGSLE---RAKQYQQVIDNFPKLSAELRQQLNNERDEPRSV-----------PPNMSTDA 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  589 gaLQEEIAKLQEKMTIQqkevesriAEQLEEEQ-RLRENVKYLNeQIATLQSELvskdealeKFSLSEcgIENLRRELEL 667
Cdd:PRK10929   107 --LEQEILQVSSQLLEK--------SRQAQQEQdRAREISDSLS-QLPQQQTEA--------RRQLNE--IERRLQTLGT 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  668 LKEEnekqaqEAQAEFTRKLAEKSVevlrlsselqnLKATSDSLESERVNKTDECEIlqteVRMRDE----QIRELNQQL 743
Cdd:PRK10929   166 PNTP------LAQAQLTALQAESAA-----------LKALVDELELAQLSANNRQEL----ARLRSElakkRSQQLDAYL 224

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  744 DEVTTQLNV--QKADSSALDDMLRLQKEGTEEKSTLLE--KTEKELVQSKEQAAKTLND--------------------- 798
Cdd:PRK10929   225 QALRNQLNSqrQREAERALESTELLAEQSGDLPKSIVAqfKINRELSQALNQQAQRMDLiasqqrqaasqtlqvrqalnt 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  799 -KEQ-------------LEKQISDLKQLAEQEKLVREMTENAINQIQLEkESIEQQLALKQNELEDFQKKQSESEVHLQE 864
Cdd:PRK10929   305 lREQsqwlgvsnalgeaLRAQVARLPEMPKPQQLDTEMAQLRVQRLRYE-DLLNKQPQLRQIRQADGQPLTAEQNRILDA 383

                          410
                   ....*....|....*.
gi 1834199290  865 -IKAQNtqkdfELVES 879
Cdd:PRK10929   384 qLRTQR-----ELLNS 394
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-118 1.58e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290    2 SDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPqpskmkAPSSFGSTGSVSKIGRPCCNHTTP 81
Cdd:PHA03307   280 SRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST------SSSSESSRGAAVSPGPSPSRSPSP 353

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1834199290   82 KSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTA 118
Cdd:PHA03307   354 SRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 1297-1571 1.97e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 43.20  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1297 EELEEKLKQAQQSEqkLQQESQTSKEKLTEIQQSLQELQDSVKQK----EELVQNLEEK-VRESSSIIEAQN------TK 1365
Cdd:pfam07111  128 EMVRKNLEEGSQRE--LEEIQRLHQEQLSSLTQAHEEALSSLTSKaeglEKSLNSLETKrAGEAKQLAEAQKeaellrKQ 205

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1366 LNESNVQLENKTSCLKETQDQLLESQKKEKQLQE---EAAKLSGELQQVQEANGDIKDSL----VKVEELVKVL---EEK 1435
Cdd:pfam07111  206 LSKTQEELEAQVTLVESLRKYVGEQVPPEVHSQTwelERQELLDTMQHLQEDRADLQATVellqVRVQSLTHMLalqEEE 285

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1436 LQAATSQLDAQQAT-NKELQELLVKSQEN----EGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESN 1510
Cdd:pfam07111  286 LTRKIQPSDSLEPEfPKKCRSLLNRWREKvfalMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKA 365

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1511 TVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEK 1571
Cdd:pfam07111  366 AEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVEQ 426
GAS pfam13851
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ...
 1386-1565 2.24e-03

Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.


Pssm-ID: 464001 [Multi-domain]  Cd Length: 200  Bit Score: 41.43  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1386 QLLESQKKE-KQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQaatsQLDAQQATNKELQELLVKSQENE 1464
Cdd:pfam13851   26 ELIKSLKEEiAELKKKEERNEKLMSEIQQENKRLTEPLQKAQEEVEELRKQLE----NYEKDKQSLKNLKARLKVLEKEL 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1465 GNLQGESLAVTEKLQQLEQANGELKEalcQKENGLKELQGKLDESNTVLESQkkshneIQDKLEQAQQKERTLQEETSKL 1544
Cdd:pfam13851  102 KDLKWEHEVLEQRFEKVERERDELYD---KFEAAIQDVQQKTGLKNLLLEKK------LQALGETLEKKEAQLNEVLAAA 172

                          170       180
                   ....*....|....*....|.
gi 1834199290 1545 AEQLSQLKQANEELQKSLQQK 1565
Cdd:pfam13851  173 NLDPDALQAVTEKLEDVLESK 193
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 686-896 2.32e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  686 KLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKAdssALDDMLR 765
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  766 -LQKEGTEEK--STLLEKTEKELVQSKEQAAKTL--NDKEQLEKQISDLKQLAEQEKLVRE---MTENAINQIQLEKESI 837
Cdd:COG3883     94 aLYRSGGSVSylDVLLGSESFSDFLDRLSALSKIadADADLLEELKADKAELEAKKAELEAklaELEALKAELEAAKAEL 173

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1834199290  838 EQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLG 896
Cdd:COG3883    174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 959-1100 2.34e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 2.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  959 KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHL--LEQITKLKSEVGETQAALSSCHT 1036
Cdd:COG1579     31 AELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEYEALQKEIESLKRRISDLED 110

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1037 DVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSK 1100
Cdd:COG1579    111 EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 687-1082 2.35e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 42.74  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  687 LAEKSVEVLRLSselqnlkatsDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSsalddMLRL 766
Cdd:pfam13166   87 LGEESIEIQEKI----------AKLKKEIKDHEEKLDAAEANLQKLDKEKEKLEADFLDECWKKIKRKKNS-----ALSE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  767 QKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDkeqlEKQISDLKQLAEQEK-LVREMTENAINQIQLEKESI-EQQLALK 844
Cdd:pfam13166  152 ALNGFKYEANFKSRLLREIEKDNFNAGVLLSD----EDRKAALATVFSDNKpEIAPLTFNVIDFDALEKAEIlIQKVIGK 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  845 QNELEDFQKKQSESEvhlqeikaqntqkdfeLVESGESL-KKLQQQLE--QKTLGHEkLQAALEE------------LKK 909
Cdd:pfam13166  228 SSAIEELIKNPDLAD----------------WVEQGLELhKAHLDTCPfcGQPLPAE-RKAALEAhfddeftefqnrLQK 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  910 EKETIIKEKEQELQQLQSKSAESesalkvvqvqleqlqqqaaasgeegsKTVAKLHDEISQLKSQAEETQSELKSTQSNL 989
Cdd:pfam13166  291 LIEKVESAISSLLAQLPAVSDLA--------------------------SLLSAFELDVEDIESEAEVLNSQLDGLRRAL 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  990 EAKSKQ-------------LEAANGS-----------------LEEEAKKSGHLLEQ--ITKLKSEVGETQAALSSCHTD 1037
Cdd:pfam13166  345 EAKRKDpfksieldsvdakIESINDLvasineliakhneitdnFEEEKNKAKKKLRLhlVEEFKSEIDEYKDKYAGLEKA 424

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1834199290 1038 VESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA 1082
Cdd:pfam13166  425 INSLEKEIKNLEAEIKKLREEIKELEAQLRDHKPGADEINKLLKA 469
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1289-1704 2.49e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.64  E-value: 2.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1289 LDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQqSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNE 1368
Cdd:COG5185     92 KKLDTKILQEYVNSLIKLPNYEWSADILISLLYLYKSEIV-ALKDELIKVEKLDEIADIEASYGEVETGIIKDIFGKLTQ 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1369 SNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQA 1448
Cdd:COG5185    171 ELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQ 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1449 TNKELQELLVKSQENEGNLQGESlavTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHneiqdKLE 1528
Cdd:COG5185    251 TSDKLEKLVEQNTDLRLEKLGEN---AESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLA-----AAE 322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1529 QAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEkGNEFDTQLAEYQKVIDEMDDA-ASVKSALLEQLQNRV 1607
Cdd:COG5185    323 AEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIE-NIVGEVELSKSSEELDSFKDTiESTKESLDEIPQNQR 401

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1608 AELETALRQANDAQKTAYLETKELRRQLESL------------ELEKSREVLSLKAQMNGASSRSGKGDEVESldieTSL 1675
Cdd:COG5185    402 GYAQEILATLEDTLKAADRQIEELQRQIEQAtssneevskllnELISELNKVMREADEESQSRLEEAYDEINR----SVR 477

                          410       420
                   ....*....|....*....|....*....
gi 1834199290 1676 AKINFLNSIIADMQQKNDALKAKVQTLET 1704
Cdd:COG5185    478 SKKEDLNEELTQIESRVSTLKATLEKLRA 506
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 999-1238 2.53e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  999 ANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITd 1078
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERA- 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1079 tlhAELQAERSSSSALHTKLSkfsdeiATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSf 1158
Cdd:COG3883     93 ---RALYRSGGSVSYLDVLLG------SESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1159 EESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAE 1238
Cdd:COG3883    163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1148-1346 2.85e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 2.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1148 KAEGERKEKSFEESIKNLQEEVTKA-------KTENLELSTGTQTT-----IKDLQERLEITNAELQHKEKMASEDAQKI 1215
Cdd:COG3206    170 REEARKALEFLEEQLPELRKELEEAeaaleefRQKNGLVDLSEEAKlllqqLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1216 ADLKTLVEAIQvANANISATNAELSTvLEVLQAEKSET---NH--IFELFEMEADMNS---ERLIEKVTGIKEELKETHL 1287
Cdd:COG3206    250 GSGPDALPELL-QSPVIQQLRAQLAE-LEAELAELSARytpNHpdVIALRAQIAALRAqlqQEAQRILASLEAELEALQA 327

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1288 QLDERQKKFEELEEKLKQAQQSEQK---LQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQ 1346
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELEAElrrLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 729-933 2.99e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  729 VRMRDEQIRELNQQLDEVTTQLnvQKADSSALDDMLR-LQKEGTEEKSTLLEKTEKELVQ-----SKEQAAKTLN---DK 799
Cdd:PRK05771     4 VRMKKVLIVTLKSYKDEVLEAL--HELGVVHIEDLKEeLSNERLRKLRSLLTKLSEALDKlrsylPKLNPLREEKkkvSV 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  800 EQLEKQISDLKQLAEQ-EKLVREMTENaINQIQLEKESIEQQLA--------------LKQNEL----------EDFQKK 854
Cdd:PRK05771    82 KSLEELIKDVEEELEKiEKEIKELEEE-ISELENEIKELEQEIErlepwgnfdldlslLLGFKYvsvfvgtvpeDKLEEL 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  855 QSESEVHLQEIKAQNTQKDFELV--------ESGESLKKLQQQlEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQ 926
Cdd:PRK05771   161 KLESDVENVEYISTDKGYVYVVVvvlkelsdEVEEELKKLGFE-RLELEEEGTPSELIREIKEELEEIEKERESLLEELK 239


                   ....*..
gi 1834199290  927 SKSAESE 933
Cdd:PRK05771   240 ELAKKYL 246
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 514-842 3.34e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 3.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  514 KARIVelesALDNERKKT-EELQcSIDEAQFCgdELNAQSQVykEKIHDLESKITKLVSATPSLQSILPPDlpsddGALQ 592
Cdd:PRK05771     8 KVLIV----TLKSYKDEVlEALH-ELGVVHIE--DLKEELSN--ERLRKLRSLLTKLSEALDKLRSYLPKL-----NPLR 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  593 EEIAKLQEKMTIQQKEVESRIAEQLEEEqrlrenVKYLNEQIATLQSELvskdEALEKfslsecgienlrrelellkeen 672
Cdd:PRK05771    74 EEKKKVSVKSLEELIKDVEEELEKIEKE------IKELEEEISELENEI----KELEQ---------------------- 121

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  673 ekqaqeaqaeftrklAEKSVEVLR-LSSELQNLKATSD-SLESERVNKTDECEILQTEVrmrDEQIRELNQQLDEVTTQL 750
Cdd:PRK05771   122 ---------------EIERLEPWGnFDLDLSLLLGFKYvSVFVGTVPEDKLEELKLESD---VENVEYISTDKGYVYVVV 183

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  751 NVQKADSSALDDMLRlqKEGTEEKSTLLEKTEKELVQSKEQAAKTLND-KEQLEKQISDLKQLAEQEKLVREmtenAINQ 829
Cdd:PRK05771   184 VVLKELSDEVEEELK--KLGFERLELEEEGTPSELIREIKEELEEIEKeRESLLEELKELAKKYLEELLALY----EYLE 257

                          330
                   ....*....|...
gi 1834199290  830 IQLEKESIEQQLA 842
Cdd:PRK05771   258 IELERAEALSKFL 270
COG5391 COG5391
Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function ...
 1255-1410 3.54e-03

Phox homology (PX) domain protein [Intracellular trafficking and secretion / General function prediction only];


Pssm-ID: 227680 [Multi-domain]  Cd Length: 524  Bit Score: 42.09  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1255 HIFELFEMEAdMNSERLIEKVTGIKEELKETHLQ-LDERQ---KKFEELEEKLkqAQQSEQKLQQESQTSKEKLTEIQ-- 1328
Cdd:COG5391    301 SIFSLFEKIL-IQLESEEESLTRLLESLNNLLLLvLNFSGvfaKRLEQNQNSI--LNEGVVQAETLRSSLKELLTQLQde 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1329 -QSLQELQDSVKQKEELVQNLEEKVRESSSIiEAQNTKLNESNV-QLENKTSCLKETQ-----DQLLESQKKEKQLQEEA 1401
Cdd:COG5391    378 iKSRESLILTDSNLEKLTDQNLEDVEELSRS-LRKNSSQRAVVSqQPEGLTSFSKLSYklrdfVQEKSRSKSIESLQQDK 456


                   ....*....
gi 1834199290 1402 AKLSGELQQ 1410
Cdd:COG5391    457 EKLEEQLAI 465
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1016-1194 3.91e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1016 QITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHA-----ELQAerss 1090
Cdd:COG1579     18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkEYEA---- 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1091 ssalhtklskFSDEIATGHKELTSKADawsqEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVT 1170
Cdd:COG1579     94 ----------LQKEIESLKRRISDLED----EILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELE 159

                          170       180
                   ....*....|....*....|....
gi 1834199290 1171 KAKTENLELSTGTQTTIKDLQERL 1194
Cdd:COG1579    160 ELEAEREELAAKIPPELLALYERI 183
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
773-1076 3.91e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 41.43  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  773 EKSTLLEKTEKELVQSKEQAaktlndKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQ 852
Cdd:COG1340      1 SKTDELSSSLEELEEKIEEL------REEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVK 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  853 KKQSESEVHLQEIKaqntqkdfELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKET--IIKEKEQELqqlqsksa 930
Cdd:COG1340     75 ELKEERDELNEKLN--------ELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTevLSPEEEKEL-------- 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  931 esesalkvvqvqleqlqqqaaasgeegSKTVAKLHDEISQLKsQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKS 1010
Cdd:COG1340    139 ---------------------------VEKIKELEKELEKAK-KALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEA 190

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1011 GHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEI 1076
Cdd:COG1340    191 QELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRAL 256
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1452-1566 3.92e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.12  E-value: 3.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1452 ELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDES-NTVLESQKKSHNEIQDKLEQA 1530
Cdd:PRK00409   517 KLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQL 596

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1834199290 1531 QQKERTLQEEtSKLAEQLSQLKQANEELQKSLQQKQ 1566
Cdd:PRK00409   597 QKGGYASVKA-HELIEARKRLNKANEKKEKKKKKQK 631
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1228-1452 4.18e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1228 ANANISATNAELSTVLEVLQAEKSEtnhifeLFEMEADMnsERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQ 1307
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAE------LDALQAEL--EELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1308 QSEQKLQQESQTSKEKLTEIQ---------------QSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQ 1372
Cdd:COG3883     86 EELGERARALYRSGGSVSYLDvllgsesfsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1373 LENKtscLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKE 1452
Cdd:COG3883    166 LEAA---KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 966-1157 4.48e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.35  E-value: 4.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  966 DEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEeakksghLLEQITKLKSEVGETQAALSSCHTDVESKTKQL 1045
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNE-------LQAELEALQAEIDKLQAEIAEAEAEIEERREEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1046 EAANAALEK--VNKEYAESRAEASDLQD---------KVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTS 1114
Cdd:COG3883     89 GERARALYRsgGSVSYLDVLLGSESFSDfldrlsalsKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEA 168

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1834199290 1115 KADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKS 1157
Cdd:COG3883    169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
Laminin_I pfam06008
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ...
 1296-1482 4.93e-03

Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.


Pssm-ID: 310534 [Multi-domain]  Cd Length: 258  Bit Score: 40.86  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1296 FEELEEKLKQAQQSEQKLQQESQT----SKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESnV 1371
Cdd:pfam06008   56 TEELQKKATQTLAKAQQVNAESERtlghAKELAEAIKNLIDNIKEINEKVATLGENDFALPSSDLSRMLAEAQRMLGE-I 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1372 QLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEAngdIKDSLVKveelvkvLEEKLQAATSQLDAQQATNK 1451
Cdd:pfam06008  135 RSRDFGTQLQNAEAELKAAQDLLSRIQTWFQSPQEENKALANA---LRDSLAE-------YEAKLSDLRELLREAAAKTR 204

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1834199290 1452 ELQELLVKSQENEGNLQGESLAVTEKLQQLE 1482
Cdd:pfam06008  205 DANRLNLANQANLREFQRKKEEVSEQKNQLE 235
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1273-1520 5.29e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 41.96  E-value: 5.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1273 EKVTGIKEELKETHLQLDERQKK------FEELEEKLKQAQQSEQKLQQESQTSkEKLTEIQQSLQELQDSVKQKEELVQ 1346
Cdd:PTZ00108  1102 EKVEKLNAELEKKEKELEKLKNTtpkdmwLEDLDKFEEALEEQEEVEEKEIAKE-QRLKSKTKGKASKLRKPKLKKKEKK 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1347 NLEEKVRESSSIIEAQNTKLNESNVQLE-----NKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDS 1421
Cdd:PTZ00108  1181 KKKSSADKSKKASVVGNSKRVDSDEKRKlddkpDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEF 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1422 LVKVEELVKVLEEKLQAATSQLDAQQATNKEL-QELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLK 1500
Cdd:PTZ00108  1261 SSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPdGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTR 1340

                          250       260
                   ....*....|....*....|
gi 1834199290 1501 ELQGKlDESNTVLESQKKSH 1520
Cdd:PTZ00108  1341 VKQAS-ASQSSRLLRRPRKK 1359
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 733-922 5.55e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 5.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  733 DEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKtlnDKEQLeKQISDLKql 812
Cdd:COG1579     16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKK---YEEQL-GNVRNNK-- 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  813 aEQEKLVREMTENAINQIQLEKESIEqqlalKQNELEDFQKKQSESEVHLQEIKAQntqkdfelvesgesLKKLQQQLEQ 892
Cdd:COG1579     90 -EYEALQKEIESLKRRISDLEDEILE-----LMERIEELEEELAELEAELAELEAE--------------LEEKKAELDE 149

                          170       180       190
                   ....*....|....*....|....*....|
gi 1834199290  893 KTlghEKLQAALEELKKEKETIIKEKEQEL 922
Cdd:COG1579    150 EL---AELEAELEELEAEREELAAKIPPEL 176
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
777-1031 6.29e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 6.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  777 LLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQS 856
Cdd:COG4372     18 LRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  857 ESEVHLQEIKAQNTQKDFELvesgESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESAL 936
Cdd:COG4372     98 QAQEELESLQEEAEELQEEL----EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  937 KVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQ 1016
Cdd:COG4372    174 QALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLE 253

                          250
                   ....*....|....*
gi 1834199290 1017 ITKLKSEVGETQAAL 1031
Cdd:COG4372    254 EVILKEIEELELAIL 268
PRK11637 PRK11637
AmiB activator; Provisional
 1305-1554 6.37e-03

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 41.22  E-value: 6.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1305 QAQQSEQKLQQESQTSKEKLTEIQQSLQ---ELQDSVKQKEELVQNLEEKVRESssiieaQNTkLNESNVQLENKTSCLK 1381
Cdd:PRK11637    41 HASDNRDQLKSIQQDIAAKEKSVRQQQQqraSLLAQLKKQEEAISQASRKLRET------QNT-LNQLNKQIDELNASIA 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1382 ETQDQllesQKKEKQL---QEEAAKLSGELQQVQeangdikdSLVKVEELVKvlEEKLQAATSQL-DAQQATNKELQELL 1457
Cdd:PRK11637   114 KLEQQ----QAAQERLlaaQLDAAFRQGEHTGLQ--------LILSGEESQR--GERILAYFGYLnQARQETIAELKQTR 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1458 V-----KSQENEGNLQGESLAVTEKLQQ--LEQANGELKEALCQKENGLKELQGKLDESNtvlesqkksHNEIQ--DKLE 1528
Cdd:PRK11637   180 EelaaqKAELEEKQSQQKTLLYEQQAQQqkLEQARNERKKTLTGLESSLQKDQQQLSELR---------ANESRlrDSIA 250

                          250       260
                   ....*....|....*....|....*.
gi 1834199290 1529 QAQQKERTLQEETSKLAEQLSQlKQA 1554
Cdd:PRK11637   251 RAEREAKARAEREAREAARVRD-KQK 275
mukB PRK04863
chromosome partition protein MukB;
1481-1657 6.60e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 6.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1481 LEQANGELKEALCQKENGLKELQGKLDESN---TVLESQKKSHNE----IQDKLEQAQQKER---TLQEETSKLAEQLSQ 1550
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAELNeaeSDLEQDYQAASDhlnlVQTALRQQEKIERyqaDLEELEERLEEQNEV 370

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1551 LKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASvksalleQLQNRVAELETALRQANDAQKTA-----Y 1625
Cdd:PRK04863   371 VEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAI-------QYQQAVQALERAKQLCGLPDLTAdnaedW 443

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1834199290 1626 LEtkELRRQLESLELeksrEVLSLKAQMNGAS 1657
Cdd:PRK04863   444 LE--EFQAKEQEATE----ELLSLEQKLSVAQ 469
SHE3 pfam17078
SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an ...
 1502-1702 6.67e-03

SWI5-dependent HO expression protein 3; SWI5-dependent HO expression protein 3 (She3) is an RNA-binding protein that binds specific mRNAs, including the mRNA of Ash1, which is invalid in cell-fate determination. She3 acts as an adapter protein that docks the myosin motor Myo4p onto an Ash1-She2p ribonucleoprotein complex. She3 seems to bind to Myo4p and Shep2p via different domains.


Pssm-ID: 293683 [Multi-domain]  Cd Length: 228  Bit Score: 40.11  E-value: 6.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1502 LQGKLDESNTVLESQKKSHNEIQDKLEQAQQKErtlqeetSKLAEQLSQLKQANEELQKSLQQKQlllEKGNEFDTQLAE 1581
Cdd:pfam17078    8 LHDQIDALTKTNLQLTVQSQNLLSKLEIAQQKE-------SKFLENLASLKHENDNLSSMLNRKE---RRLKDLEDQLSE 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1582 YQKVIDEMDDAASVKSALLEQLQNRVAELETALRQAnDAQKTAYLETKELRRQLESLELEKSREVL-SLKAQMNGASSRS 1660
Cdd:pfam17078   78 LKNSYEELTESNKQLKKRLENSSASETTLEAELERL-QIQYDALVDSQNEYKDHYQQEINTLQESLeDLKLENEKQLENY 156

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1834199290 1661 GKGDEVESLDIETslaKINFLNSIIADMQQKNDALKAKVQTL 1702
Cdd:pfam17078  157 QQRISSNDKDIDT---KLDSYNNKFKNLDNIYVNKNNKLLTK 195
TPR_MLP1_2 pfam07926
TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of ...
 962-1086 7.05e-03

TPR/MLP1/MLP2-like protein; The sequences featured in this family are similar to a region of human TPR protein and to yeast myosin-like proteins 1 (MLP1) and 2 (MLP2). These proteins share a number of features; for example, they all have coiled-coil regions and all three are associated with nuclear pores. TPR is thought to be a component of nuclear pore complex- attached intra-nuclear filaments, and is implicated in nuclear protein import. Moreover, its N-terminal region is involved in the activation of oncogenic kinases, possibly by mediating the dimerization of kinase domains or by targeting these kinases to the nuclear pore complex. MLP1 and MLP2 are involved in the process of telomere length regulation, where they are thought to interact with proteins such as Tel1p and modulate their activity.


Pssm-ID: 462316 [Multi-domain]  Cd Length: 129  Bit Score: 38.39  E-value: 7.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  962 AKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESK 1041
Cdd:pfam07926    4 SSLQSEIKRLKEEAADAEAQLQKLQEDLEKQAEIAREAQQNYERELVLHAEDIKALQALREELNELKAEIAELKAEAESA 83

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1834199290 1042 TKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQA 1086
Cdd:pfam07926   84 KAELEESEESWEEQKKELEKELSELEKRIEDLNEQNKLLHDQLES 128
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 772-1131 7.23e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 41.10  E-value: 7.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  772 EEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQ-EKLVREMTEnainqIQLEKESIEQQLALKQNELED 850
Cdd:COG5185    211 ETGNLGSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKlEKLVEQNTD-----LRLEKLGENAESSKRLNENAN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  851 FQKKQSESevhLQEIKAQNTQKdfelvesgESLKKLQQQLEQKTLGHEKLQAaLEELKKEKETIIKEKEQELQQLQSKSA 930
Cdd:COG5185    286 NLIKQFEN---TKEKIAEYTKS--------IDIKKATESLEEQLAAAEAEQE-LEESKRETETGIQNLTAEIEQGQESLT 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  931 ESESALKvvqvqleqlqqqAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK----QLEAANGSLEEE 1006
Cdd:COG5185    354 ENLEAIK------------EEIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQeilaTLEDTLKAADRQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1007 AKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAAlEKVNKEYAESRAEASDLQDKVKEITDTLHAELQA 1086
Cdd:COG5185    422 IEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE-EAYDEINRSVRSKKEDLNEELTQIESRVSTLKAT 500

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1834199290 1087 ERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQ 1131
Cdd:COG5185    501 LEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLI 545
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 1115-1422 7.24e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 41.38  E-value: 7.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1115 KADAWSQEMLQKEKELQELRQQLQDSQDSQTKLkaegerKEKSFEESIKNLQEEVTKAKTENLElSTGTQTTIKDLQERL 1194
Cdd:PLN03229   423 KREAVKTPVRELEGEVEKLKEQILKAKESSSKP------SELALNEMIEKLKKEIDLEYTEAVI-AMGLQERLENLREEF 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1195 EITNAELQHKEKMASEDAQKIAD--LKTLVEAIQVAN----------ANISATNAELSTVLEVLQAEKSEtnhifelfEM 1262
Cdd:PLN03229   496 SKANSQDQLMHPVLMEKIEKLKDefNKRLSRAPNYLSlkykldmlneFSRAKALSEKKSKAEKLKAEINK--------KF 567

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1263 EADMNSERLIEKVTGIKEELKETHL-QLDERQKKFEELEEKLKQAQQSEQK-------LQQESQTSKEKLTEIQQSLQEL 1334
Cdd:PLN03229   568 KEVMDRPEIKEKMEALKAEVASSGAsSGDELDDDLKEKVEKMKKEIELELAgvlksmgLEVIGVTKKNKDTAEQTPPPNL 647

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1335 QDSV-KQKEELVQNLEEKVRESS-----SIIEAQNTKLNES-NVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGE 1407
Cdd:PLN03229   648 QEKIeSLNEEINKKIERVIRSSDlkskiELLKLEVAKASKTpDVTEKEKIEALEQQIKQKIAEALNSSELKEKFEELEAE 727

                          330
                   ....*....|....*
gi 1834199290 1408 LQQVQEANGDIKDSL 1422
Cdd:PLN03229   728 LAAARETAAESNGSL 742
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 898-1385 7.44e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.19  E-value: 7.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  898 EKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLqqqaaasgEEGSKTVAKLHDEISQLKS---Q 974
Cdd:PRK10929    26 KQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQYQQVI--------DNFPKLSAELRQQLNNERDeprS 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  975 AEETQSELKSTQSNLEAKSKQLEAANgSLEEEAKKSGHLLEQITKLKSEVGETQAALSschtDVESKTKQLEAANAALEK 1054
Cdd:PRK10929    98 VPPNMSTDALEQEILQVSSQLLEKSR-QAQQEQDRAREISDSLSQLPQQQTEARRQLN----EIERRLQTLGTPNTPLAQ 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1055 VnkEYAESRAEASDLQDKVKEItdtlhaELqAERSSSSalhtklskfSDEIATGHKELTSKADAwsqemlQKEKELQELR 1134
Cdd:PRK10929   173 A--QLTALQAESAALKALVDEL------EL-AQLSANN---------RQELARLRSELAKKRSQ------QLDAYLQALR 228

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1135 QQLQDSQDSQTKLKAEgeRKEKsFEESIKNLQEEVTKAKTENLELSTgtqttikdlqerleITNAELQHKEKMASEdaQK 1214
Cdd:PRK10929   229 NQLNSQRQREAERALE--STEL-LAEQSGDLPKSIVAQFKINRELSQ--------------ALNQQAQRMDLIASQ--QR 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1215 IADLKTLveaiQVANAnisatnaeLSTVLEVLQAEKSETnhifelfemeadMNSERLIEKVTGIKEELKETHL-----QL 1289
Cdd:PRK10929   290 QAASQTL----QVRQA--------LNTLREQSQWLGVSN------------ALGEALRAQVARLPEMPKPQQLdtemaQL 345

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1290 DERQKKFEELEEKLkqaqqseQKLQQESQTSKEKLTEIQQSLqeLQDSVKQKEELVQNLEEKVreSSSIIEAqnTKLNES 1369
Cdd:PRK10929   346 RVQRLRYEDLLNKQ-------PQLRQIRQADGQPLTAEQNRI--LDAQLRTQRELLNSLLSGG--DTLILEL--TKLKVA 412

                          490
                   ....*....|....*.
gi 1834199290 1370 NVQLENktsCLKETQD 1385
Cdd:PRK10929   413 NSQLED---ALKEVNE 425
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 1273-1400 7.60e-03

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 40.82  E-value: 7.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1273 EKVTGIKEELKETH--LQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEE 1350
Cdd:pfam15742  128 EKILELQQKLEHAHkvCLTDTCILEKKQLEERIKEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEM 207

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1351 KVRESSSIIEAQNTKL----NESNVQLENKTSClKETQDQLLESQKKEKQLQEE 1400
Cdd:pfam15742  208 TNSQQQLRIQQQEAQLkqleNEKRKSDEHLKSN-QELSEKLSSLQQEKEALQEE 260
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1435-1614 7.60e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 7.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1435 KLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVle 1514
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN-- 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1515 sqkKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSL-QQKQLLLEKGNEFDTQLAEYQKVIdemddaa 1593
Cdd:COG1579     89 ---KEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELaELEAELEEKKAELDEELAELEAEL------- 158

                          170       180
                   ....*....|....*....|.
gi 1834199290 1594 svksallEQLQNRVAELETAL 1614
Cdd:COG1579    159 -------EELEAEREELAAKI 172
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1522-1722 7.67e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.22  E-value: 7.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1522 EIQDKLEQAQQKERTLQEEtsklAEQLSQLKQANEELQKSL----QQKQLLLEKGNEFDTQL-AEYQKVIDEMDdaASVK 1596
Cdd:COG5022    872 QSAQRVELAERQLQELKID----VKSISSLKLVNLELESEIielkKSLSSDLIENLEFKTELiARLKKLLNNID--LEEG 945

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1597 SALLEQLQNRVAELETALRQANDAQKT---AYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIE- 1672
Cdd:COG5022    946 PSIEYVKLPELNKLHEVESKLKETSEEyedLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEv 1025

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1834199290 1673 TSLAK-INFLNSIIADMQQKNDAlkAKVQTLETLPMDFTKPHAFDALTKRK 1722
Cdd:COG5022   1026 AELQSaSKIISSESTELSILKPL--QKLKGLLLLENNQLQARYKALKLRRE 1074
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 696-1333 8.42e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 40.96  E-value: 8.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  696 RLSSELQNLKAT-SDSLESERVNKTDEC---EILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGT 771
Cdd:pfam10174   25 KLGSSMNSIKTFwSPELKKERALRKEEAariSVLKEQYRVTQEENQHLQLTIQALQDELRAQRDLNQLLQQDFTTSPVDG 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  772 EEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESieQQLALKQNELEDF 851
Cdd:pfam10174  105 EDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQS--KGLPKKSGEEDWE 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  852 QKKQ-SESEVHLQEIKAQNTQKDFELVESGESLKKlQQQLEQKTLGHEKLQAALEeLKKEK----ETIIKEKEQELQQLQ 926
Cdd:pfam10174  183 RTRRiAEAEMQLGHLEVLLDQKEKENIHLREELHR-RNQLQPDPAKTKALQTVIE-MKDTKisslERNIRDLEDEVQMLK 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  927 SksaesESALKVVQVQLEQLQQQAAASGEEGSKTvaklhdEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANgsleee 1006
Cdd:pfam10174  261 T-----NGLLHTEDREEEIKQMEVYKSHSKFMKN------KIDQLKQELSKKESELLALQTKLETLTNQNSDCK------ 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1007 akksghllEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAElqa 1086
Cdd:pfam10174  324 --------QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVK--- 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1087 ERSSSsALHTKLSKFSDEIATGHKELTSKADA-----------------WSQEMLQKEKELQELRQQLQDSQDSQTKLKA 1149
Cdd:pfam10174  393 ERKIN-VLQKKIENLQEQLRDKDKQLAGLKERvkslqtdssntdtalttLEEALSEKERIIERLKEQREREDRERLEELE 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1150 EGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQT----------TIKDL-----QERLEITNAELQHKEKMASEDAQK 1214
Cdd:pfam10174  472 SLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSlassglkkdsKLKSLeiaveQKKEECSKLENQLKKAHNAEEAVR 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1215 IAD-----LKTLVEAIQVANANISATNAELSTVLEVL---QAEKSETNHIFELFEMEADMNSERLIEKVTGIK----EEL 1282
Cdd:pfam10174  552 TNPeindrIRLLEQEVARYKEESGKAQAEVERLLGILrevENEKNDKDKKIAELESLTLRQMKEQNKKVANIKhgqqEMK 631

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1283 KETHLQLDERQKKFEELEEKLKQAQQSE-----QKLQQESQTSKEKLTEIQQSLQE 1333
Cdd:pfam10174  632 KKGAQLLEEARRREDNLADNSQQLQLEElmgalEKTRQELDATKARLSSTQQSLAE 687
F-BAR_PACSIN1 cd07680
The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein ...
 1386-1571 8.92e-03

The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Protein kinase C and Casein kinase Substrate in Neurons 1 (PACSIN1); F-BAR domains are dimerization modules that bind and bend membranes and are found in proteins involved in membrane dynamics and actin reorganization. Protein kinase C and Casein kinase Substrate in Neurons (PACSIN) proteins, also called Synaptic dynamin-associated proteins (Syndapins), act as regulators of cytoskeletal and membrane dynamics. Vetebrates harbor three isoforms with distinct expression patterns and specific functions. PACSIN 1 or Syndapin I is expressed specifically in the brain and is localized in neurites and synaptic boutons. It binds the brain-specific proteins dynamin I, synaptojanin, synapsin I, and neural Wiskott-Aldrich syndrome protein (nWASP), and functions as a link between the cytoskeletal machinery and synaptic vesicle endocytosis. PACSIN 1 interacts with huntingtin and may be implicated in the neuropathology of Huntington's disease. It contains an N-terminal F-BAR domain and a C-terminal SH3 domain. F-BAR domains form banana-shaped dimers with a positively-charged concave surface that binds to negatively-charged lipid membranes. They can induce membrane deformation in the form of long tubules.


Pssm-ID: 153364 [Multi-domain]  Cd Length: 258  Bit Score: 40.03  E-value: 8.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1386 QLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKvEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQEneg 1465
Cdd:cd07680     51 QLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLN-EDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQK--- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1466 nlqgeslAVTEKLQQLEQANGELKEAlCQKEN--GLKELQGKLDESNTVlESQKKshneIQDKLEQAQQKERTLQEETSK 1543
Cdd:cd07680    127 -------PWAKKMKELEAAKKAYHLA-CKEEKlaMTREANSKAEQSVTP-EQQKK----LQDKVDKCKQDVQKTQEKYEK 193

                          170       180
                   ....*....|....*....|....*....
gi 1834199290 1544 LAEQLSQLK-QANEELQKSLQQKQLLLEK 1571
Cdd:cd07680    194 VLDDVGKTTpQYMENMEQVFEQCQQFEEK 222
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 720-935 9.10e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  720 DECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDK 799
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  800 EQLEKQISDLKQLAEQEklvreMTENAINQIQL-------EKESIEQQLALKQnELEDFQKKQSESEVHLQEIKAQNTQK 872
Cdd:COG3883     96 YRSGGSVSYLDVLLGSE-----SFSDFLDRLSAlskiadaDADLLEELKADKA-ELEAKKAELEAKLAELEALKAELEAA 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1834199290  873 DFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESA 935
Cdd:COG3883    170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAA 232
Laminin_I pfam06008
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ...
 1174-1454 9.19e-03

Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.


Pssm-ID: 310534 [Multi-domain]  Cd Length: 258  Bit Score: 40.09  E-value: 9.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1174 TENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKI-----------ADLKTLVEAIQVANANISATNAELSTV 1242
Cdd:pfam06008    1 LLSLNSLTGALPAPYKINYNLENLTKQLQEYLSPENAHKIQIeilekelsslaQETEELQKKATQTLAKAQQVNAESERT 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1243 LevlqaeksetNHIFELfemeaDMNSERLIEKVTGIKEelKETHLQLDERQKKFEELEEKLKQAQQSEQKLQqeSQTSKE 1322
Cdd:pfam06008   81 L----------GHAKEL-----AEAIKNLIDNIKEINE--KVATLGENDFALPSSDLSRMLAEAQRMLGEIR--SRDFGT 141

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1323 KLTEIQQSLQELQDSVKQKEELVQNLEEkvrESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQkkekqlqeeaa 1402
Cdd:pfam06008  142 QLQNAEAELKAAQDLLSRIQTWFQSPQE---ENKALANALRDSLAEYEAKLSDLRELLREAAAKTRDAN----------- 207

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1834199290 1403 klsGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQ 1454
Cdd:pfam06008  208 ---RLNLANQANLREFQRKKEEVSEQKNQLEETLKTARDSLDAANLLLQEID 256
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
883-1086 9.34e-03

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 40.83  E-value: 9.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  883 LKKLQQQLEQKTLGHEKLQAALEELKK------EKETIIKEKE--QELQQLQSKSAESESALkvvqvqleqlqqqaaaSG 954
Cdd:COG0497    174 LEELRADEAERARELDLLRFQLEELEAaalqpgEEEELEEERRrlSNAEKLREALQEALEAL----------------SG 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290  955 EEGS-------------------KTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAAN---GSLEEEAKKSGH 1012
Cdd:COG0497    238 GEGGaldllgqalralerlaeydPSLAELAERLESALIELEEAASELRRYLDSLEFDPERLEEVEerlALLRRLARKYGV 317

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1834199290 1013 LLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASdlqdkvKEITDTLHAELQA 1086
Cdd:COG0497    318 TVEELLAYAEELRAELAELENSDERLEELEAELAEAEAELLEAAEKLSAARKKAA------KKLEKAVTAELAD 385
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1509-1703 9.42e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 9.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1509 SNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEfdtQLAEYQKVIDE 1588
Cdd:COG3883     14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---EIEERREELGE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1589 M-------DDAASVKSALLE-----QLQNRVaeleTALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGA 1656
Cdd:COG3883     91 RaralyrsGGSVSYLDVLLGsesfsDFLDRL----SALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAEL 166

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1834199290 1657 SSRSgkgDEVESLdIETSLAKINFLNSIIADMQQKNDALKAKVQTLE 1703
Cdd:COG3883    167 EAAK---AELEAQ-QAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 1279-1414 9.76e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 40.76  E-value: 9.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199290 1279 KEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSI 1358
Cdd:pfam05262  209 QEDAKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKPADTSSPKEDKQVAENQKREIEKAQI 288

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199290 1359 IEAQNTKLNESNVQlENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEA 1414
Cdd:pfam05262  289 EIKKNDEEALKAKD-HKAFDLKQESKASEKEAEDKELEAQKKREPVAEDLQKTKPQ 343
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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