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Conserved domains on  [gi|1834199245|ref|NP_001369122|]
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excitatory amino acid transporter 1, isoform E [Drosophila melanogaster]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
20-448 5.13e-112

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 337.09  E-value: 5.13e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  20 LTMATVIGVFVGGLIGFIIKNSTGEWskreimyISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITY 98
Cdd:COG1301     5 LTLQILIALVLGILLGLLLPELVAAV-------LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  99 YFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKAskvlTPDTLMDLVRNMFTDNIIQstmfqhrteiyentsispa 178
Cdd:COG1301    78 FLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAA----EAPSLLDFLLNIIPSNIFE------------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qPMENwefksaqregSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEME 258
Cdd:COG1301   135 -AFAE----------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYG 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 259 siAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPR 337
Cdd:COG1301   204 --LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKS 281
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 338 VTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDV 417
Cdd:COG1301   282 VASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGI 361
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1834199245 418 SLIIAVDWLLDRFRTTINVMCDALGTILVNH 448
Cdd:COG1301   362 ALILGIDRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
20-448 5.13e-112

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 337.09  E-value: 5.13e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  20 LTMATVIGVFVGGLIGFIIKNSTGEWskreimyISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITY 98
Cdd:COG1301     5 LTLQILIALVLGILLGLLLPELVAAV-------LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  99 YFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKAskvlTPDTLMDLVRNMFTDNIIQstmfqhrteiyentsispa 178
Cdd:COG1301    78 FLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAA----EAPSLLDFLLNIIPSNIFE------------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qPMENwefksaqregSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEME 258
Cdd:COG1301   135 -AFAE----------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYG 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 259 siAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPR 337
Cdd:COG1301   204 --LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKS 281
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 338 VTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDV 417
Cdd:COG1301   282 VASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGI 361
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1834199245 418 SLIIAVDWLLDRFRTTINVMCDALGTILVNH 448
Cdd:COG1301   362 ALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-449 2.26e-107

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 324.47  E-value: 2.26e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  20 LTMATVIGVFVGGLIGFIIKNStgewskreIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL--------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  99 YFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASkvltPDTLMDLVRNMFTDNIIQSTMfqhrteiyentsispa 178
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAAE----APSLLDFILNIIPSNIFEALA---------------- 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qpmenwefksaqreGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEme 258
Cdd:pfam00375 133 --------------EGNVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-- 196
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 259 SIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPR 337
Cdd:pfam00375 197 YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAeKNLGVSES 276
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 338 VTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDV 417
Cdd:pfam00375 277 IASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGI 356
                         410       420       430
                  ....*....|....*....|....*....|..
gi 1834199245 418 SLIIAVDWLLDRFRTTINVMCDALGTILVNHL 449
Cdd:pfam00375 357 ALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
25-446 1.89e-32

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 128.73  E-value: 1.89e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  25 VIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITYYFVTT 103
Cdd:PRK11283   13 LIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 104 ISAVILGICLVTTLRPGQGAKIVETQTESIDK----ASKVLTPD-TLMDLVRNMFTDNIIQSTMfqhrteiyentsispa 178
Cdd:PRK11283   93 TVAIILGITLANVFQPGAGIDMSQLATVDISKyqstTEEVQSHShGLMGTILSLIPTNIFASMA---------------- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qpmenwefksaqreGSNVLGLVMFSVILGTTIGRMREK-GQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEM 257
Cdd:PRK11283  157 --------------KGEMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANF 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 258 EsiAATIQSLGWYFITVMIGLFLHGF---GTIAVIFFLGTRRLpyryIAKLSQVLATAFGTGSSSATMPLTIKCLDNMGI 334
Cdd:PRK11283  223 G--FASLWPLAKLVLLVYFAILFFALvvlGIVARLCGLSIWIL----IRILKDELILAYSTASSETVLPRIIEKMEAYGA 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 335 DPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEP 414
Cdd:PRK11283  297 PKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPL 376
                         410       420       430
                  ....*....|....*....|....*....|..
gi 1834199245 415 KDVSLIIAVDWLLDRFRTTINVMCDALGTILV 446
Cdd:PRK11283  377 EGLAFIAGVDRILDMARTALNVVGNALAVLVI 408
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
20-448 5.13e-112

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 337.09  E-value: 5.13e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  20 LTMATVIGVFVGGLIGFIIKNSTGEWskreimyISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITY 98
Cdd:COG1301     5 LTLQILIALVLGILLGLLLPELVAAV-------LKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKTLLY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  99 YFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKAskvlTPDTLMDLVRNMFTDNIIQstmfqhrteiyentsispa 178
Cdd:COG1301    78 FLVTTTIALVIGLVVANLFQPGAGLNLDLADAAAAEAA----EAPSLLDFLLNIIPSNIFE------------------- 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qPMENwefksaqregSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEME 258
Cdd:COG1301   135 -AFAE----------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYG 203
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 259 siAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPR 337
Cdd:COG1301   204 --LDALGSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAeEKLGVSKS 281
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 338 VTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDV 417
Cdd:COG1301   282 VASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGI 361
                         410       420       430
                  ....*....|....*....|....*....|.
gi 1834199245 418 SLIIAVDWLLDRFRTTINVMCDALGTILVNH 448
Cdd:COG1301   362 ALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
20-449 2.26e-107

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 324.47  E-value: 2.26e-107
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  20 LTMATVIGVFVGGLIGFIIKNStgewskreIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITY 98
Cdd:pfam00375   1 LLLQILIALVLGILIGLFFPEL--------AAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLY 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  99 YFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDKASkvltPDTLMDLVRNMFTDNIIQSTMfqhrteiyentsispa 178
Cdd:pfam00375  73 FLVTTAIAALIGLLVANVFQPGSGLALIAASLKEAKAAE----APSLLDFILNIIPSNIFEALA---------------- 132
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qpmenwefksaqreGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEme 258
Cdd:pfam00375 133 --------------EGNVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGT-- 196
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 259 SIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCL-DNMGIDPR 337
Cdd:pfam00375 197 YGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAeKNLGVSES 276
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 338 VTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDV 417
Cdd:pfam00375 277 IASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGI 356
                         410       420       430
                  ....*....|....*....|....*....|..
gi 1834199245 418 SLIIAVDWLLDRFRTTINVMCDALGTILVNHL 449
Cdd:pfam00375 357 ALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
25-446 1.89e-32

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 128.73  E-value: 1.89e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  25 VIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITYYFVTT 103
Cdd:PRK11283   13 LIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIGAKTIIYFEVIT 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 104 ISAVILGICLVTTLRPGQGAKIVETQTESIDK----ASKVLTPD-TLMDLVRNMFTDNIIQSTMfqhrteiyentsispa 178
Cdd:PRK11283   93 TVAIILGITLANVFQPGAGIDMSQLATVDISKyqstTEEVQSHShGLMGTILSLIPTNIFASMA---------------- 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 179 qpmenwefksaqreGSNVLGLVMFSVILGTTIGRMREK-GQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEM 257
Cdd:PRK11283  157 --------------KGEMLPIIFFSVLFGLGLSSLPAThREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANF 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 258 EsiAATIQSLGWYFITVMIGLFLHGF---GTIAVIFFLGTRRLpyryIAKLSQVLATAFGTGSSSATMPLTIKCLDNMGI 334
Cdd:PRK11283  223 G--FASLWPLAKLVLLVYFAILFFALvvlGIVARLCGLSIWIL----IRILKDELILAYSTASSETVLPRIIEKMEAYGA 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 335 DPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEP 414
Cdd:PRK11283  297 PKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPL 376
                         410       420       430
                  ....*....|....*....|....*....|..
gi 1834199245 415 KDVSLIIAVDWLLDRFRTTINVMCDALGTILV 446
Cdd:PRK11283  377 EGLAFIAGVDRILDMARTALNVVGNALAVLVI 408
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
57-446 6.08e-32

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 126.71  E-value: 6.08e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  57 GEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQTESIDK 135
Cdd:PRK13027   37 GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGMNIDLRSLDAASL 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 136 ASKVLTPDTLMDLVRnmFTDNIIQSTMFqhrteiyentsispaqpmenwefkSAQREGsNVLGLVMFSVILGTTIGRMRE 215
Cdd:PRK13027  117 AGYAKNAQSLKGTAG--FLLKLIPTTAV------------------------DAFAKG-DILQVLLFSVLFGSALSLLGE 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 216 KGQLLQDFFTTLSEAMMTITSWVIWISPLGV----AFLIAAKIIemesiaATIQSLGWYFITVMIGLFLHGFGTIAVIFF 291
Cdd:PRK13027  170 RAKRVNRLIDELSHVLFRIMGFIIKLAPLGVlgaiAFTTGKYGV------GSLKQLGMLVAVFYLTCFVFVVVVLGAVMR 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 292 LGTRRLpYRYIAKLSQVLATAFGTGSSSATMPLTIKCLDNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREM 371
Cdd:PRK13027  244 LAGFSV-FKLIRYLREELLIVLGTASSDAVLPQVMRKLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNT 322
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1834199245 372 SYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPK-DVSLIIAVDWLLDRFRTTINVMCDALGTILV 446
Cdd:PRK13027  323 PLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPAIPVlGLVLILPVDWFMGIARALTNLIGNCVATVVV 398
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
57-446 2.03e-30

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 122.70  E-value: 2.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  57 GEIFLRMLKCLIVPLLVSSITSAIGGL-DLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQG---------AKIV 126
Cdd:PRK01663   38 GDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGAGmnidpatldAKAV 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 127 ETQTEsidKASKVLTPDTLMdlvrnmftdNIIQSTMFqhrteiyentsispaqpmenwefkSAQREGsNVLGLVMFSVIL 206
Cdd:PRK01663  118 AQYAA---QAHEQGTVDFLM---------DIIPTTVV------------------------GAFASG-DILQVLLFAVLF 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 207 GTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGV----AFLIAAKIIemesiaATIQSLGWYFITVMIGLFLHG 282
Cdd:PRK01663  161 GFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGAfgamAFTIGKYGV------GSLVQLGQLIGCFYITCILFV 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 283 FGTIAVIFFLGTRRLpYRYIAKLSQVLATAFGTGSSSATMPLTIKCLDNMGIDPRVTRFVIPVGATINMDGTALYEAVAA 362
Cdd:PRK01663  235 FVVLGAIARLTGFSI-FKFIRYIKEELLIVLGTSSSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAA 313
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 363 LFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEP-KDVSLIIAVDWLLDRFRTTINVMCDAL 441
Cdd:PRK01663  314 VFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPHIPvAGLALILGIDRFMSEARALTNLIGNGV 393

                  ....*
gi 1834199245 442 GTILV 446
Cdd:PRK01663  394 ATVVV 398
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
25-395 5.69e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 76.44  E-value: 5.69e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  25 VIGVFVGGLIGFIIKNSTGewskreimYISFPGEIFLRMLKClIVPLLVSS-ITSAIGGLDLSMSSKIATRAITYYFVT- 102
Cdd:PRK13628   21 LIGLVLGILLALLSPPAAE--------AVGLLGTLFVGALKA-VAPILVFVlVMASIANHKKGQKTNIRPILVLYLLGTf 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 103 --TISAVILGICLVTTLrpgqgakIVETQTESIDKASKVLtpDTLMDLVRNMFtDNIIQSTMfqhrteiyentsispaqp 180
Cdd:PRK13628   92 laALVAVVASFLFPSTL-------VLVASAADISPPQGIV--EVLKTLLLSLV-DNPINALL------------------ 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 181 menwefksaqreGSNVLGLVMFSVILGTTigrMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAakiiemESI 260
Cdd:PRK13628  144 ------------NANYIGILAWAIGLGLA---LRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVA------STL 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 261 AAT-IQSLGWY--FITVMIG-LFLHGFGTIAVIFFLGTRRLPYRYIAK-LSQVLATAFGTGSSSATMPLTIKCLDNMGID 335
Cdd:PRK13628  203 AETgFSALAGYaqLLAVLVGcMLFVALVVNPLIVFWKIRRNPYPLVFTcLRESGVTAFFTRSSAANIPVNMALCEKLGLD 282
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 336 PRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGI 395
Cdd:PRK13628  283 EDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGV 342
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
194-448 7.16e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 75.47  E-value: 7.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 194 SNVLGLVMFSVILGTTigrMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIieMESIAATIQSLGWYFIT 273
Cdd:PRK14695   59 ANYIGILSWAVIFGIA---MREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTI--SDKGVGSLANYGILLVL 133
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 274 VMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLA-TAFGTGSSSATMPLTIKCLDNMGIDPRVTRFVIPVGATINMD 352
Cdd:PRK14695  134 LVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRVSGvTAFFTRSSATNIPVNMKLCHDLGLNPDTYSVSIPLGSTINMA 213
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 353 GTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLL----D 428
Cdd:PRK14695  214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgviqD 293
                         250       260
                  ....*....|....*....|
gi 1834199245 429 RFRTTINVMCDALGTILVNH 448
Cdd:PRK14695  294 SCETALNSSTDVLFTAVAEY 313
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
25-396 1.89e-14

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 74.82  E-value: 1.89e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  25 VIGVFVGGLIGFIIKNSTgewskreiMYISFPGEIFLRMLKClIVPLLV-----SSITSAIGGLDLSMSSkiatrAITYY 99
Cdd:COG3633    20 LIGLVLGILLALLSPEAA--------KSVGLLGTLFVGALKA-VAPILVfvlvmSAIANHKQGQKTNMKP-----IIVLY 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 100 FVTTISAVILGIcLVTTLRPgqgakivetQTESIDKASKVLTP-----DTLMDLVRNMFtDNIIQSTMfqhrteiyents 174
Cdd:COG3633    86 LLGTFLAALVAV-VASFLFP---------TTLTLVAAAADLTPpggigEVLKTLLLNVV-DNPVNALA------------ 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 175 ispaqpmenwefksaqreGSNVLGLVMFSVILGTTigrMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAaki 254
Cdd:COG3633   143 ------------------NANYIGILAWAIGLGLA---LRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVA--- 198
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 255 iemESIAAT-IQSLGWYF--ITVMIGLFLhgfgTIA-----VIFFLGTRRLPYRYIAK-LSQVLATAFGTGSSSATMPLT 325
Cdd:COG3633   199 ---STVATTgFSALLGYAhlLAVLVGCML----FVAlvvnpLIVFLKIRRNPYPLVFTcLRESGITAFFTRSSAANIPVN 271
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1834199245 326 IKCLDNMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASIGAAGIP 396
Cdd:COG3633   272 MALCEKLGLDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIEVDLPTALLLSVVAAVSACGASGVA 342
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
26-421 1.16e-10

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 63.31  E-value: 1.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245  26 IGVFVGGLIGFIIKNSTGEWS---KREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMS-SKIATRAITYYFV 101
Cdd:COG1823    36 TGLGLGILFGLILQLIYGAGSpviKQSIDWFNIVGNGYVRLLQMIVMPLVFVSILSAITKLKNASSlGKISGLIIGILLG 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 102 TTISAVILGIcLVTTLRPGQGAKIVETQTEsidkaskvltpdtlmdlvrnmftdnIIQSTMFQHRTEIYENTSIS----- 176
Cdd:COG1823   116 TTAIAALVGI-LVALLFGLTAEGLTQGAAE-------------------------TARGEALEERLGEVEDLSLPqqils 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 177 --PAQPMENWefkSAQREGSnVLGLVMFSVILGTTIGRMR----EKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLI 250
Cdd:COG1823   170 fiPTNPFADL---TGARPTS-TIAVVIFAAFLGIAALGLRrkkpEQAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALM 245
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 251 AaKIIEMESIAAtIQSLGWYFITVMIGLFL----HGfgtiavIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTI 326
Cdd:COG1823   246 T-KVVATSDFAD-ILNLGKFVVASYVALIImfivHL------LLLALAGLNPLTYFKKVWPVLTFAFTSRSSAGTIPLNI 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1834199245 327 KCL-DNMGIDprvtrfvipvgatinmdgtalyEAVAalfiaqyrEMSYSFGtivavsitataASIG---AAGIPQAGLVt 402
Cdd:COG1823   318 ETQtKRLGVP----------------------EGIA--------NFAASFG-----------ATIGqngCAGIYPAMLA- 355
                         410
                  ....*....|....*....
gi 1834199245 403 mVMVLDTVGLEPKDVSLII 421
Cdd:COG1823   356 -VMIAPTVGINPLDPSFIL 373
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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