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Conserved domains on  [gi|1845979303|ref|NP_001370744|]
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Homeobox protein dve-1 [Caenorhabditis elegans]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10647766)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  21557080|26464018|27768937|1357790
SCOP:  4000291

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 179-244 1.15e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


:

Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 61.11  E-value: 1.15e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845979303  179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCK 244
Cdd:smart00389   3 RKRTSFTP-EQLEELEKEFQKNPYPSREEREELAKKLG----------LSERQVKVWFQNRRAKWK 57
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 179-244 1.15e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 61.11  E-value: 1.15e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845979303  179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCK 244
Cdd:smart00389   3 RKRTSFTP-EQLEELEKEFQKNPYPSREEREELAKKLG----------LSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 179-245 3.15e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 57.25  E-value: 3.15e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1845979303 179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCKR 245
Cdd:cd00086     2 RKRTRFTP-EQLEELEKEFEKNPYPSREEREELAKELG----------LTERQVKIWFQNRRAKLKR 57
Homeodomain pfam00046
Homeodomain;
179-245 3.60e-08

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 49.04  E-value: 3.60e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1845979303 179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCKR 245
Cdd:pfam00046   2 RKRTTFTP-EQLEELEKEFQENPYPSAEEREELAAQLG----------LTERQVKVWFQNRRAKWKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
189-245 6.91e-05

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 42.04  E-value: 6.91e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845979303 189 ELPVLEKWFEENPHPTWmqidqytqclnncAYRENY---PHISQHNVKIWFKNRRAKCKR 245
Cdd:COG5576    62 QLMVLEREFEINPYPSS-------------ITRIKLsllLNMPPKSVQIWFQNKRAKEKK 108
 
Name Accession Description Interval E-value
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 179-244 1.15e-12

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 61.11  E-value: 1.15e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845979303  179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCK 244
Cdd:smart00389   3 RKRTSFTP-EQLEELEKEFQKNPYPSREEREELAKKLG----------LSERQVKVWFQNRRAKWK 57
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 179-245 3.15e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 57.25  E-value: 3.15e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1845979303 179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCKR 245
Cdd:cd00086     2 RKRTRFTP-EQLEELEKEFEKNPYPSREEREELAKELG----------LTERQVKIWFQNRRAKLKR 57
Homeodomain pfam00046
Homeodomain;
179-245 3.60e-08

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 49.04  E-value: 3.60e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1845979303 179 RSRLMFDPlTELPVLEKWFEENPHPTWMQIDQYTQCLNncayrenyphISQHNVKIWFKNRRAKCKR 245
Cdd:pfam00046   2 RKRTTFTP-EQLEELEKEFQENPYPSAEEREELAAQLG----------LTERQVKVWFQNRRAKWKR 57
COG5576 COG5576
Homeodomain-containing transcription factor [Transcription];
189-245 6.91e-05

Homeodomain-containing transcription factor [Transcription];


Pssm-ID: 227863 [Multi-domain]  Cd Length: 156  Bit Score: 42.04  E-value: 6.91e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845979303 189 ELPVLEKWFEENPHPTWmqidqytqclnncAYRENY---PHISQHNVKIWFKNRRAKCKR 245
Cdd:COG5576    62 QLMVLEREFEINPYPSS-------------ITRIKLsllLNMPPKSVQIWFQNKRAKEKK 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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