NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2046363545|ref|NP_001381959|]
View 

transmembrane protein 209 isoform 2 [Rattus norvegicus]

Protein Classification

CytochromB561_N domain-containing protein( domain architecture ID 11184663)

CytochromB561_N domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
CytochromB561_N super family cl46356
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
4-559 0e+00

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


The actual alignment was detected with superfamily member pfam09786:

Pssm-ID: 480696  Cd Length: 579  Bit Score: 542.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545   4 EVSPSPsLIDRTIRMRKETESRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWR 83
Cdd:pfam09786   3 EVYRNP-ALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFIS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545  84 YFKYTVA----------PTSLVVSPGQQTLLGLKPAVVQTT------PPRDLAATQISPSPPspsiqgqSVLSYSPSRSP 147
Cdd:pfam09786  82 LFKYLFAvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVtthrkkPPKSKSSPQSPSPVL-------VPLHQSVSPSS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 148 STSPKFATSCMTGYSPQLQGLSSGGLGSYSPaVTYSPvsgySKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTAYNS 227
Cdd:pfam09786 155 SESRKGGDKSPAGSGKKLRSFSTSSKSPASP-SVYLR----GSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 228 PTDKEDYMTDlRTLDTFLRSEEEKQHRVKLGSPDSTSPSTsptfwNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEAD 307
Cdd:pfam09786 230 ATIGKEIRTE-KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGD 303
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 308 LISKQAAEEVWArVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGC-PELQIGEASVTSLKQAALVK 386
Cdd:pfam09786 304 LPSPMSMEENIE-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGEDGLLHLKRAALVQ 382
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 387 A--------------PLIPTL--NAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGD---FKGRRWDTDLPTDSA 447
Cdd:pfam09786 383 AldtstlslqspqlpPLIPFLqeWAKGLLPQSSVNQEYLVQRIKELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSH 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 448 IIMHVFCTYLDsrlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCVYQSAINPPHYELIYQRHVYSLP 517
Cdd:pfam09786 463 LLFYLFCAYLD-----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSL 537
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 2046363545 518 KGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFG 559
Cdd:pfam09786 538 QGRTNLFDSILQFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Name Accession Description Interval E-value
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
4-559 0e+00

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 542.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545   4 EVSPSPsLIDRTIRMRKETESRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWR 83
Cdd:pfam09786   3 EVYRNP-ALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFIS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545  84 YFKYTVA----------PTSLVVSPGQQTLLGLKPAVVQTT------PPRDLAATQISPSPPspsiqgqSVLSYSPSRSP 147
Cdd:pfam09786  82 LFKYLFAvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVtthrkkPPKSKSSPQSPSPVL-------VPLHQSVSPSS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 148 STSPKFATSCMTGYSPQLQGLSSGGLGSYSPaVTYSPvsgySKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTAYNS 227
Cdd:pfam09786 155 SESRKGGDKSPAGSGKKLRSFSTSSKSPASP-SVYLR----GSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 228 PTDKEDYMTDlRTLDTFLRSEEEKQHRVKLGSPDSTSPSTsptfwNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEAD 307
Cdd:pfam09786 230 ATIGKEIRTE-KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGD 303
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 308 LISKQAAEEVWArVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGC-PELQIGEASVTSLKQAALVK 386
Cdd:pfam09786 304 LPSPMSMEENIE-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGEDGLLHLKRAALVQ 382
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 387 A--------------PLIPTL--NAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGD---FKGRRWDTDLPTDSA 447
Cdd:pfam09786 383 AldtstlslqspqlpPLIPFLqeWAKGLLPQSSVNQEYLVQRIKELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSH 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 448 IIMHVFCTYLDsrlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCVYQSAINPPHYELIYQRHVYSLP 517
Cdd:pfam09786 463 LLFYLFCAYLD-----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSL 537
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 2046363545 518 KGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFG 559
Cdd:pfam09786 538 QGRTNLFDSILQFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Name Accession Description Interval E-value
CytochromB561_N pfam09786
Cytochrome B561, N terminal; Members of this family are found in the N terminal region of ...
4-559 0e+00

Cytochrome B561, N terminal; Members of this family are found in the N terminal region of cytochrome B561, as well as in various other putative uncharacterized proteins.


Pssm-ID: 462899  Cd Length: 579  Bit Score: 542.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545   4 EVSPSPsLIDRTIRMRKETESRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWR 83
Cdd:pfam09786   3 EVYRNP-ALSAALTANSLRPSKSVLLFWGLLSIASASILLFEMSREGISQEAAYSFVKLYYIEYALAFIGSLSALFKFIS 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545  84 YFKYTVA----------PTSLVVSPGQQTLLGLKPAVVQTT------PPRDLAATQISPSPPspsiqgqSVLSYSPSRSP 147
Cdd:pfam09786  82 LFKYLFAvqskspskgtKTPSRLTNQQLGLLGLKPNDSSFVtthrkkPPKSKSSPQSPSPVL-------VPLHQSVSPSS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 148 STSPKFATSCMTGYSPQLQGLSSGGLGSYSPaVTYSPvsgySKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTAYNS 227
Cdd:pfam09786 155 SESRKGGDKSPAGSGKKLRSFSTSSKSPASP-SVYLR----GSPVPLNSSPLPSDRNYENSVQSSPEIDSAVSTPWSRKR 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 228 PTDKEDYMTDlRTLDTFLRSEEEKQHRVKLGSPDSTSPSTsptfwNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEAD 307
Cdd:pfam09786 230 ATIGKEIRTE-KMLERFLAEVDEKITESAFGKASPSNVSG-----SANRSGSTRSTPLRSVRMSPGSQKFTTPPKKGEGD 303
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 308 LISKQAAEEVWArVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGC-PELQIGEASVTSLKQAALVK 386
Cdd:pfam09786 304 LPSPMSMEENIE-AFENLGIYPQIEQWRDRLRQWISLTILNPLVEKIETSHIQVMQAAAkPTLQLGEDGLLHLKRAALVQ 382
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 387 A--------------PLIPTL--NAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGD---FKGRRWDTDLPTDSA 447
Cdd:pfam09786 383 AldtstlslqspqlpPLIPFLqeWAKGLLPQSSVNQEYLVQRIKELAEGTCLKNYRWNSGGSvyrKKGKKWDLELPTDSH 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2046363545 448 IIMHVFCTYLDsrlppHPKY----------PDGKTFTSQHFVQTPNKPDVTNENVFCVYQSAINPPHYELIYQRHVYSLP 517
Cdd:pfam09786 463 LLFYLFCAYLD-----HPKWsknplflgvlPPGEPFPERYVVVISGKPAVKHPGACILAVGKQSPPHFALYWDKKLQNSL 537
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 2046363545 518 KGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFG 559
Cdd:pfam09786 538 QGRTNLFDSILQFCHRIKTGYGGYVRGINLGSSGINILPVLE 579
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH