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Conserved domains on  [gi|2131399612|ref|NP_001384316|]
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putative protein FAM90A7 [Homo sapiens]

Protein Classification

transcription initiation factor TFIID subunit 1( domain architecture ID 10633817)

transcription initiation factor TFIID subunit 1 (TAF1) is part of the TFIID complex that plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 3.79e-19

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


:

Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 80.51  E-value: 3.79e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2131399612  41 RLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 25-420 9.73e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.31  E-value: 9.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612   25 RAPVGPR-----SPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKpRAEANPGPLNKD 99
Cdd:PHA03247  2599 RAPVDDRgdprgPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQAS 2677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  100 KGEKEERPRQQDPQRNALLHMFSGKPPEKPlpngkgsTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSV 179
Cdd:PHA03247  2678 SPPQRPRRRAARPTVGSLTSLADPPPPPPT-------PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  180 LASLSPL--RKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAVRPQ 257
Cdd:PHA03247  2751 PGGPARParPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP 2830

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  258 AQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELRAPENLQPPPAA 337
Cdd:PHA03247  2831 PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  338 TELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSlLAAPSFHSP 417
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVP-QPAPSREAP 2989


                   ...
gi 2131399612  418 EKP 420
Cdd:PHA03247  2990 ASS 2992
 
Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 3.79e-19

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 80.51  E-value: 3.79e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2131399612  41 RLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-420 9.73e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.31  E-value: 9.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612   25 RAPVGPR-----SPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKpRAEANPGPLNKD 99
Cdd:PHA03247  2599 RAPVDDRgdprgPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQAS 2677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  100 KGEKEERPRQQDPQRNALLHMFSGKPPEKPlpngkgsTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSV 179
Cdd:PHA03247  2678 SPPQRPRRRAARPTVGSLTSLADPPPPPPT-------PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  180 LASLSPL--RKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAVRPQ 257
Cdd:PHA03247  2751 PGGPARParPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP 2830

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  258 AQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELRAPENLQPPPAA 337
Cdd:PHA03247  2831 PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  338 TELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSlLAAPSFHSP 417
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVP-QPAPSREAP 2989


                   ...
gi 2131399612  418 EKP 420
Cdd:PHA03247  2990 ASS 2992
 
Name Accession Description Interval E-value
zf-CCHC_6 pfam15288
Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.
 41-82 3.79e-19

Zinc knuckle; This Zinc knuckle is found in FAM90A mammalian proteins.


Pssm-ID: 464616 [Multi-domain]  Cd Length: 42  Bit Score: 80.51  E-value: 3.79e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2131399612  41 RLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENL 82
Cdd:pfam15288   1 RVKCKNCGAFGHTARSKRCPIKCWNGALVPQPLGSKKEKENL 42
PHA03247 PHA03247
large tegument protein UL36; Provisional
 25-420 9.73e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.31  E-value: 9.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612   25 RAPVGPR-----SPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKpRAEANPGPLNKD 99
Cdd:PHA03247  2599 RAPVDDRgdprgPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQAS 2677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  100 KGEKEERPRQQDPQRNALLHMFSGKPPEKPlpngkgsTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSV 179
Cdd:PHA03247  2678 SPPQRPRRRAARPTVGSLTSLADPPPPPPT-------PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  180 LASLSPL--RKASLSSSSSLGPKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAVRPQ 257
Cdd:PHA03247  2751 PGGPARParPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPP 2830

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  258 AQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELRAPENLQPPPAA 337
Cdd:PHA03247  2831 PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQ 2910

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2131399612  338 TELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLENGRWSSSlLAAPSFHSP 417
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVP-QPAPSREAP 2989


                   ...
gi 2131399612  418 EKP 420
Cdd:PHA03247  2990 ASS 2992
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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