|
Name |
Accession |
Description |
Interval |
E-value |
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
66-274 |
2.39e-112 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 322.78 E-value: 2.39e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKAL 141
Cdd:pfam01135 1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVpesfKSYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 142 DVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDPMllssgRVRLVVGDGRMGFAEEAPYDAIHVGAAAP 221
Cdd:pfam01135 79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2168696669 222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
|
|
| pimt |
TIGR00080 |
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ... |
62-281 |
1.10e-73 |
|
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]
Pssm-ID: 272896 [Multi-domain] Cd Length: 215 Bit Score: 224.71 E-value: 1.10e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEG 137
Cdd:TIGR00080 1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVAMMTELL--ELKPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 138 AKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDGRMGFAEEAPYDAIHVG 217
Cdd:TIGR00080 79 MKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVT 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2168696669 218 AAAPVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKEKQW 281
Cdd:TIGR00080 154 AAGPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
|
|
| PRK13942 |
PRK13942 |
protein-L-isoaspartate O-methyltransferase; Provisional |
70-278 |
1.05e-52 |
|
protein-L-isoaspartate O-methyltransferase; Provisional
Pssm-ID: 184409 Cd Length: 212 Bit Score: 170.97 E-value: 1.05e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKSNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGS 145
Cdd:PRK13942 8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAIMCELL--DLKEGMKVLEIGT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 146 GSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPVVPQ 225
Cdd:PRK13942 86 GSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2168696669 226 ALIDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK13942 161 PLIEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
|
|
| Pcm |
COG2518 |
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ... |
75-275 |
1.40e-51 |
|
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442008 [Multi-domain] Cd Length: 197 Bit Score: 167.57 E-value: 1.40e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 75 LRKNGIiKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGSGSGIL 150
Cdd:COG2518 4 LRPRGV-TDPRVLDAMRAVPRELFVpealRELAYADRALPIGHGQTISQPYIVARMLEAL--DLKPGDRVLEIGTGSGYQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 151 TACFARMVGHsgkVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPVVPQALIDQ 230
Cdd:COG2518 81 AAVLARLAGR---VYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEALLEQ 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2168696669 231 LKPGGRLILPVGPaGGNQMLEQYDKLQDGsVKMKPLMGVIYVPLT 275
Cdd:COG2518 153 LAPGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
|
|
| pcm |
PRK00312 |
protein-L-isoaspartate(D-aspartate) O-methyltransferase; |
71-278 |
2.44e-46 |
|
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
Pssm-ID: 178974 [Multi-domain] Cd Length: 212 Bit Score: 154.59 E-value: 2.44e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 71 LIHNLRKNGIiKTDKVFEVMLATDRS--------HYAksnpYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALD 142
Cdd:PRK00312 12 LVLRLRAEGI-LDERVLEAIEATPRElfvpeafkHKA----YENRALPIGCGQTISQPYMVARMTELL--ELKPGDRVLE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 143 VGSGSGILTACFARMVGHsgkVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPV 222
Cdd:PRK00312 85 IGTGSGYQAAVLAHLVRR---VFSVERIKTLQWEAKRRLKQ-----LGLHNVSVRHGDGWKGWPAYAPFDRILVTAAAPE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2168696669 223 VPQALIDQLKPGGRLILPVGpaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK00312 157 IPRALLEQLKEGGILVAPVG--GEEQQLLTRVRKRGGRFEREVLEEVRFVPLVKGE 210
|
|
| PRK13944 |
PRK13944 |
protein-L-isoaspartate O-methyltransferase; Provisional |
71-274 |
5.54e-33 |
|
protein-L-isoaspartate O-methyltransferase; Provisional
Pssm-ID: 140001 Cd Length: 205 Bit Score: 119.92 E-value: 5.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 71 LIHNLRKNGIIKTDKVFEVMLATDRSHYA----KSNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGSG 146
Cdd:PRK13944 5 LVEELVREGIIKSERVKKAMLSVPREEFVmpeyRMMAYEDRPLPLFAGATISAPHMVAMMCELI--EPRPGMKILEVGTG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 147 SGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmLLSSGRVRLVVGDGRMGFAEEAPYDAIHVGAAAPVVPQA 226
Cdd:PRK13944 83 SGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIER----LGYWGVVEVYHGDGKRGLEKHAPFDAIIVTAAASTIPSA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2168696669 227 LIDQLKPGGRLILPVGPAGGnQMLEQYDKLQDGsVKMKPLMGVIYVPL 274
Cdd:PRK13944 159 LVRQLKDGGVLVIPVEEGVG-QVLYKVVKRGEK-VEKRAITYVLFVPL 204
|
|
| methyltran_FxLD |
TIGR04364 |
methyltransferase, FxLD system; Members of this family resemble occur regularly in the ... |
69-241 |
2.14e-20 |
|
methyltransferase, FxLD system; Members of this family resemble occur regularly in the vicinity of lantibiotic biosynthesis enzymes and their probable target, the FxLD family of putative ribosomal natural product precursor (TIGR04363). Members resemble protein-L-isoaspartate O-methyltransferase (TIGR00080) and a predicted methyltranserase, TIGR04188, of another putative peptide modification system.
Pssm-ID: 275158 Cd Length: 394 Bit Score: 89.73 E-value: 2.14e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 69 SELIHNLRKNGIIKTDKVFEVMLATDRSHYAKSNP----YM----------DSPQSIgfqATISAPHMHAYALELLfdQL 134
Cdd:TIGR04364 6 AALVDELREDGVIRSPRVEAAFRTVPRHLFAPGAPlekaYAanravvtkrdEDGRAL---SSVSAPHIQAMMLEQA--GV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 135 HEGAKALDVGSGsGILTACFARMVGHSGKVIGIDHIKELVDdsitnvkKDDPMLLSSG--RVRLVVGDGRMGFAEEAPYD 212
Cdd:TIGR04364 81 EPGMRVLEIGSG-GYNAALLAELVGPSGEVTTVDIDEDVTD-------RARACLAAAGypQVTVVLADAEAGVPELAPYD 152
|
170 180
....*....|....*....|....*....
gi 2168696669 213 AIHVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR04364 153 RIIVTVGAWDIPPAWLDQLAPGGRLVVPL 181
|
|
| PRK13943 |
PRK13943 |
protein-L-isoaspartate O-methyltransferase; Provisional |
64-241 |
1.61e-19 |
|
protein-L-isoaspartate O-methyltransferase; Provisional
Pssm-ID: 237568 [Multi-domain] Cd Length: 322 Bit Score: 86.44 E-value: 1.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 64 GGASHSELIHNLRKNGIikTDKVFEVMLATDRS-----HYAKSNPYMD----SPQSIGFQATISAPHMHAYALELLfdQL 134
Cdd:PRK13943 3 EFFMREKLFWILKKYGI--SDHIAKAFLEVPREefltkSYPLSYVYEDivlvSYDDGEEYSTSSQPSLMALFMEWV--GL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 135 HEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDGRMGFAEEAPYDAI 214
Cdd:PRK13943 79 DKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVRR-----LGIENVIFVCGDGYYGVPEFAPYDVI 153
|
170 180
....*....|....*....|....*..
gi 2168696669 215 HVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:PRK13943 154 FVTVGVDEVPETWFTQLKEGGRVIVPI 180
|
|
| Gcd14 |
COG2519 |
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ... |
134-238 |
4.25e-12 |
|
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442009 [Multi-domain] Cd Length: 249 Bit Score: 64.41 E-value: 4.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 134 LHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmLLSSGRVRLVVGDGRMGFAEEaPYDA 213
Cdd:COG2519 89 IFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLER----FGLPDNVELKLGDIREGIDEG-DVDA 163
|
90 100
....*....|....*....|....*..
gi 2168696669 214 IHVGAAAP--VVPQAlIDQLKPGGRLI 238
Cdd:COG2519 164 VFLDMPDPweALEAV-AKALKPGGVLV 189
|
|
| methyltr_grsp |
TIGR04188 |
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ... |
134-246 |
4.41e-10 |
|
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).
Pssm-ID: 275041 Cd Length: 363 Bit Score: 59.68 E-value: 4.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 134 LHEGAKALDVGSGSGILTACFARMVGhsgkvigidhikelvDDSITNVKKDdPMLLSSGRVRL---------VVGDGRMG 204
Cdd:TIGR04188 105 VEDGHRVLEIGTGTGYSAALLCHRLG---------------DDNVTSVEVD-PGLAARAASALaaagyaptvVTGDGLLG 168
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2168696669 205 FAEEAPYDAIHVGAAAPVVPQALIDQLKPGGRLILPVG---PAGG 246
Cdd:TIGR04188 169 HPPRAPYDRIIATCAVRRVPPAWLRQTRPGGVILTTLSgwlYGGG 213
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
128-239 |
5.64e-10 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 56.18 E-value: 5.64e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 128 ELLFDQLHEGAKALDVGSGSGILTACFARMvGHsgKVIGIDhikeLVDDSITNVKKddpmLLSSGRVRLVVGDGR-MGFA 206
Cdd:COG2227 16 ALLARLLPAGGRVLDVGCGTGRLALALARR-GA--DVTGVD----ISPEALEIARE----RAAELNVDFVQGDLEdLPLE 84
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2168696669 207 EEaPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG2227 85 DG-SFDLVicsevleHLPDPAALL-RELARLLKPGGLLLL 122
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
136-239 |
1.58e-09 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 54.06 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 136 EGAKALDVGSGSGILTACFARMVGHsGKVIGIDhikeLVDDSITNVKKDDPmllssgRVRLVVGDGRmGFAEEAPYDAIH 215
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALLAERFPG-ARVTGVD----LSPEMLARARARLP------NVRFVVADLR-DLDPPEPFDLVV 68
|
90 100 110
....*....|....*....|....*....|
gi 2168696669 216 VGAA------APVVPQALIDQLKPGGRLIL 239
Cdd:COG4106 69 SNAAlhwlpdHAALLARLAAALAPGGVLAV 98
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
126-239 |
2.50e-09 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 54.94 E-value: 2.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 126 ALELLFD--QLHEGAKALDVGSGSGILTACFARMVGHsgKVIGID-------HIKELVDDsitnvkkddpmLLSSGRVRL 196
Cdd:COG2230 39 KLDLILRklGLKPGMRVLDIGCGWGGLALYLARRYGV--RVTGVTlspeqleYARERAAE-----------AGLADRVEV 105
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2168696669 197 VVGDGRmGFAEEAPYDAI-------HVGAAA-PVVPQALIDQLKPGGRLIL 239
Cdd:COG2230 106 RLADYR-DLPADGQFDAIvsigmfeHVGPENyPAYFAKVARLLKPGGRLLL 155
|
|
| PrmA |
COG2264 |
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis]; |
127-239 |
3.51e-09 |
|
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441865 [Multi-domain] Cd Length: 284 Bit Score: 56.33 E-value: 3.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 127 LELLFDQLHEGAKALDVGSGSGILtACFARMVGHsGKVIGIDhIKEL-VDDSITNVKKDDpmllSSGRVRLVVGDGRmgf 205
Cdd:COG2264 139 LEALEKLLKPGKTVLDVGCGSGIL-AIAAAKLGA-KRVLAVD-IDPVaVEAARENAELNG----VEDRIEVVLGDLL--- 208
|
90 100 110
....*....|....*....|....*....|....*....
gi 2168696669 206 aEEAPYDAIhVgA---AAPVVPQA--LIDQLKPGGRLIL 239
Cdd:COG2264 209 -EDGPYDLV-V-AnilANPLIELApdLAALLKPGGYLIL 244
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
123-239 |
5.65e-09 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 53.84 E-value: 5.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 123 HAYALELLfdQLHEGAKALDVGSGSGILTACFARmvgHSGKVIGIDHIKELVDDSITNVKKDDPmllssgRVRLVVGDG- 201
Cdd:COG2226 11 REALLAAL--GLRPGARVLDLGCGTGRLALALAE---RGARVTGVDISPEMLELARERAAEAGL------NVEFVVGDAe 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2168696669 202 RMGFAEEApYDAIHVGAAAPVVP--QALIDQ----LKPGGRLIL 239
Cdd:COG2226 80 DLPFPDGS-FDLVISSFVLHHLPdpERALAEiarvLKPGGRLVV 122
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
141-235 |
7.88e-09 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 52.18 E-value: 7.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 141 LDVGSGSGILTACFARMVGHsgKVIGIDHIKELVDDSITNVKKDDPmllssgRVRLVVGDGR-MGFAEEaPYDAIHVGAA 219
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGGA--RVTGVDLSPEMLERARERAAEAGL------NVEFVQGDAEdLPFPDG-SFDLVVSSGV 72
|
90 100
....*....|....*....|....
gi 2168696669 220 APVVPQALIDQ--------LKPGG 235
Cdd:pfam13649 73 LHHLPDPDLEAalreiarvLKPGG 96
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
126-269 |
2.25e-08 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 53.00 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 126 ALELLFDQLHEGAKALDVGSGSGILTACFARMVGHsgKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGD-GRMG 204
Cdd:COG0500 16 ALLALLERLPKGGRVLDLGCGTGRNLLALAARFGG--RVIGIDLSPEAIALARARAAK-----AGLGNVEFLVADlAELD 88
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2168696669 205 FAEEAPYDAI-------HVgaaAPVVPQALID----QLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGV 269
Cdd:COG0500 89 PLPAESFDLVvafgvlhHL---PPEEREALLRelarALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLR 161
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
139-241 |
4.00e-07 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 47.42 E-value: 4.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 139 KALDVGSGSGILTACFARmvGHSGKVIGIDhikelVDDSITNVKKDDPMLLSSGRVRLVVGDGRMG-FAEEAPYDAIHVG 217
Cdd:cd02440 1 RVLDLGCGTGALALALAS--GPGARVTGVD-----ISPVALELARKAAAALLADNVEVLKGDAEELpPEADESFDVIISD 73
|
90 100 110
....*....|....*....|....*....|.
gi 2168696669 218 AAAPVV---PQALIDQ----LKPGGRLILPV 241
Cdd:cd02440 74 PPLHHLvedLARFLEEarrlLKPGGVLVLTL 104
|
|
| CbiT |
TIGR02469 |
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes ... |
117-241 |
4.32e-07 |
|
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes the CbiT methylase which is responsible, in part (along with CbiE), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 274148 [Multi-domain] Cd Length: 124 Bit Score: 48.09 E-value: 4.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 117 ISAPHMHAYALELLfdQLHEGAKALDVGSGSGILTACFARMVGhSGKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRL 196
Cdd:TIGR02469 2 MTKREVRALTLAKL--RLRPGDVLWDIGAGTGSVTIEAARLVP-NGRVYAIERNPEALDLIERNLRR-----FGVSNIVI 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2168696669 197 VVGDgrmgfAEEAPY------DAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR02469 74 VEGD-----APEAPEallpdpDAVFVGGSGgllQEILEAVERRLRPGGRIVLNA 122
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
124-239 |
4.57e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 49.94 E-value: 4.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 124 AYALELLfdQLHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDPmllssgRVRLVVGDG-R 202
Cdd:PRK08317 9 ARTFELL--AVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKERAAGLGP------NVEFVRGDAdG 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2168696669 203 MGFAEEApYDAI-------HVGAaapvvPQALIDQ----LKPGGRLIL 239
Cdd:PRK08317 81 LPFPDGS-FDAVrsdrvlqHLED-----PARALAEiarvLRPGGRVVV 122
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
134-239 |
1.97e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 46.64 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 134 LHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVGDgrmgfAEEAP--- 210
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQK-----LGFDNVEFEQGD-----IEELPell 70
|
90 100 110
....*....|....*....|....*....|....*....
gi 2168696669 211 ----YD------AIHVGAAAPVVPQALIDQLKPGGRLIL 239
Cdd:pfam13847 71 eddkFDvvisncVLNHIPDPDKVLQEILRVLKPGGRLII 109
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
137-239 |
6.23e-06 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 46.30 E-value: 6.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 137 GAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDdsitNVKKDDPMLLSSGRVRLVVGDgrmgfAEEAPY----- 211
Cdd:PRK00216 52 GDKVLDLACGTGDLAIALAKAVGKTGEVVGLDFSEGMLA----VGREKLRDLGLSGNVEFVQGD-----AEALPFpdnsf 122
|
90 100 110
....*....|....*....|....*....|....*..
gi 2168696669 212 DAIHVGAAAPVVPQalIDQ--------LKPGGRL-IL 239
Cdd:PRK00216 123 DAVTIAFGLRNVPD--IDKalremyrvLKPGGRLvIL 157
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
131-174 |
1.06e-05 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 45.71 E-value: 1.06e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 2168696669 131 FDQLHEGAKALDVGSGSGIltACF--ARMVGHSGKVIGIDHIKELV 174
Cdd:PRK11873 72 LAELKPGETVLDLGSGGGF--DCFlaARRVGPTGKVIGVDMTPEML 115
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
141-239 |
1.11e-05 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 43.04 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 141 LDVGSGSGILTACFARMVGHsgkVIGIDHIKELVDDSITNVKKDDpmllssgrVRLVVGDG-RMGFAEEApYDAIHVGAA 219
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGAR---VTGVDISPEMLELAREKAPREG--------LTFVVGDAeDLPFPDNS-FDLVLSSEV 68
|
90 100
....*....|....*....|....*.
gi 2168696669 220 A---PVVPQAL--IDQ-LKPGGRLIL 239
Cdd:pfam08241 69 LhhvEDPERALreIARvLKPGGILII 94
|
|
| cbiT |
PRK00377 |
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional |
126-241 |
1.74e-05 |
|
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
Pssm-ID: 234740 Cd Length: 198 Bit Score: 44.79 E-value: 1.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 126 ALELLFDQLHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDPMllssGRVRLVVGDGRMGF 205
Cdd:PRK00377 30 ALALSKLRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKFGVL----NNIVLIKGEAPEIL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2168696669 206 AEEAP-YDAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:PRK00377 106 FTINEkFDRIFIGGGSeklKEIISASWEIIKKGGRIVIDA 145
|
|
| Ubie_methyltran |
pfam01209 |
ubiE/COQ5 methyltransferase family; |
136-238 |
4.81e-05 |
|
ubiE/COQ5 methyltransferase family;
Pssm-ID: 395966 [Multi-domain] Cd Length: 228 Bit Score: 43.58 E-value: 4.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 136 EGAKALDVGSGSGILTACFARMVGHSGKVIGIDhikelVDDSITNVKKDDPMLLSSGRVRLVVGDGRMGFAEEAPYDAIH 215
Cdd:pfam01209 42 RGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLD-----INENMLKEGEKKAKEEGKYNIEFLQGNAEELPFEDDSFDIVT 116
|
90 100
....*....|....*....|....*....
gi 2168696669 216 VGAA---APVVPQALIDQ---LKPGGRLI 238
Cdd:pfam01209 117 ISFGlrnFPDYLKVLKEAfrvLKPGGRVV 145
|
|
| prmA |
PRK00517 |
50S ribosomal protein L11 methyltransferase; |
127-239 |
6.23e-05 |
|
50S ribosomal protein L11 methyltransferase;
Pssm-ID: 234786 [Multi-domain] Cd Length: 250 Bit Score: 43.22 E-value: 6.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 127 LELLFDQLHEGAKALDVGSGSGILtACFARMVGHsGKVIGIDhIKEL-VDDSITNVKKDDpmllssgrVRLVVGDGrmgf 205
Cdd:PRK00517 110 LEALEKLVLPGKTVLDVGCGSGIL-AIAAAKLGA-KKVLAVD-IDPQaVEAARENAELNG--------VELNVYLP---- 174
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2168696669 206 AEEAPYDAIhVgA---AAPVVpqALIDQ----LKPGGRLIL 239
Cdd:PRK00517 175 QGDLKADVI-V-AnilANPLL--ELAPDlarlLKPGGRLIL 211
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
128-168 |
1.46e-04 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 41.81 E-value: 1.46e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2168696669 128 ELLFDQLHE--GAKALDVGSGSGILTACFARMvghSGKVIGID 168
Cdd:PRK14968 13 FLLAENAVDkkGDRVLEVGTGSGIVAIVAAKN---GKKVVGVD 52
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
128-239 |
1.69e-04 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 41.71 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 128 ELLFDQL--HEGAKALDVGSGSGILTACFARMVGHSgKVIGIDhIKEL-VDDSITNVKKDDPmllssGRVRLVVGDGRMG 204
Cdd:COG2813 39 RLLLEHLpePLGGRVLDLGCGYGVIGLALAKRNPEA-RVTLVD-VNARaVELARANAAANGL-----ENVEVLWSDGLSG 111
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2168696669 205 FAEEaPYDAI------HVGAAAPV-VPQALIDQ----LKPGGRLIL 239
Cdd:COG2813 112 VPDG-SFDLIlsnppfHAGRAVDKeVAHALIADaarhLRPGGELWL 156
|
|
| TrmR |
COG4122 |
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ... |
133-235 |
3.89e-04 |
|
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443298 Cd Length: 173 Bit Score: 40.17 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 133 QLHEGAKALDVGSGSGILTACFARMVGHSGKVIGIDHIKELVDDSITNVKKDDpmllSSGRVRLVVGDGR--MGFAEEAP 210
Cdd:COG4122 13 RLLGAKRILEIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAG----LADRIRLILGDALevLPRLADGP 88
|
90 100
....*....|....*....|....*...
gi 2168696669 211 YDAIHVGAAAPVVP---QALIDQLKPGG 235
Cdd:COG4122 89 FDLVFIDADKSNYPdylELALPLLRPGG 116
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
121-239 |
5.71e-04 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 39.98 E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 121 HMHAYALELLFDQlhEGAKALDVGSGSGILTACFARMVGHsgkVIGIDHIKELVDdsITNVKKDDpmllssgrVRLVVGD 200
Cdd:COG4976 33 LLAEELLARLPPG--PFGRVLDLGCGTGLLGEALRPRGYR---LTGVDLSEEMLA--KAREKGVY--------DRLLVAD 97
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2168696669 201 GRMGFAEEAPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG4976 98 LADLAEPDGRFDLIvaadvltYLGDLAAVF-AGVARALKPGGLFIF 142
|
|
| PLN02366 |
PLN02366 |
spermidine synthase |
184-235 |
6.39e-04 |
|
spermidine synthase
Pssm-ID: 215208 [Multi-domain] Cd Length: 308 Bit Score: 40.78 E-value: 6.39e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2168696669 184 DDPmllssgRVRLVVGDGR--MGFAEEAPYDAIHVGAAAPVVP-QALIDQ---------LKPGG 235
Cdd:PLN02366 143 DDP------RVNLHIGDGVefLKNAPEGTYDAIIVDSSDPVGPaQELFEKpffesvaraLRPGG 200
|
|
| PRK08287 |
PRK08287 |
decarboxylating cobalt-precorrin-6B (C(15))-methyltransferase; |
124-239 |
5.38e-03 |
|
decarboxylating cobalt-precorrin-6B (C(15))-methyltransferase;
Pssm-ID: 181354 Cd Length: 187 Bit Score: 36.90 E-value: 5.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 124 AYALELLfdQLHEGAKALDVGSGSG---ILTAC-FARMvghsgKVIGIDHIKELVDDSITNVKKddpmlLSSGRVRLVVG 199
Cdd:PRK08287 21 ALALSKL--ELHRAKHLIDVGAGTGsvsIEAALqFPSL-----QVTAIERNPDALRLIKENRQR-----FGCGNIDIIPG 88
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2168696669 200 DGRMGFAEEApyDAIHVGAAAPVVpQALID----QLKPGGRLIL 239
Cdd:PRK08287 89 EAPIELPGKA--DAIFIGGSGGNL-TAIIDwslaHLHPGGRLVL 129
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
131-239 |
5.64e-03 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 36.80 E-value: 5.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2168696669 131 FDQLHEGaKALDVGSGSGILTACFARMVGHsGKVIGIDHIKELVDDSITNVKKDDPMllssgRVRLVVGDGRMGFaEEAP 210
Cdd:pfam05175 27 LPKDLSG-KVLDLGCGAGVLGAALAKESPD-AELTMVDINARALESARENLAANGLE-----NGEVVASDVYSGV-EDGK 98
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2168696669 211 YDAI------HVG-AAAPVVPQALI----DQLKPGGRLIL 239
Cdd:pfam05175 99 FDLIisnppfHAGlATTYNVAQRFIadakRHLRPGGELWI 138
|
|
| |
