View
Concise Results
Standard Results
Full Results
prolyl endopeptidase [Homo sapiens]
Protein Classification
prolyl oligopeptidase family serine peptidase ( domain architecture ID 11445431 )
prolyl oligopeptidase family serine peptidase is a S9 family peptidase which catalyzes the cleavage of peptide bonds, specifically the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues
List of domain hits
Name
Accession
Description
Interval
E-value
PreP
COG1505 Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
4-704
0e+00
Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
Pssm-ID: 441114 [Multi-domain]
Cd Length: 673
Bit Score: 860.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 4 L Q YP DVY RD ETA vqdy HGHKIC DPY A WLED P DS EQ T K A F V E AQN KI T VPF L EQC P I R GLYKE R MT EL YD Y PKYSCH FK K G 83
Cdd:COG1505 4 L T YP ATR RD DVV ---- DTTAVA DPY R WLED D DS PE T L A W V K AQN AV T RAY L AAI P R R EALRA R LL EL LN Y DRIPAP FK R G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 84 K RY FY F Y N T GLQNQ R VL Y V Q D S L EG E AR V F LDPN I LS D DGT VA L RGYAF S E DG EYF AY G LS AS GSD WVTIKFMK V DGAKE 163
Cdd:COG1505 80 G RY YN F W N D GLQNQ G VL R V R D G L DP E WE V L LDPN A LS E DGT WV L GAWSL S P DG RRL AY S LS EG GSD ARVVRVFD V ATGEF 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 164 LP D VL E RV K F S CM AW T h DG K G MF Y NS Y P qqdg KSD G TE T STNLHQ K L YYH VL GT D QSED I L CA E F P - D E P KWMG G AEL S D 242
Cdd:COG1505 160 VE D GF E WE K K S GV AW L - DG T G FV Y SR Y G ---- EPE G SL T DSGYPR K V YYH RR GT P QSED E L VF E G P p D D P ERYV G VSV S E 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 243 DGRY V L L S IRE G c DPV N R L WYC DL QQE ssgiagil KW V K L IDN F EGE Y DY V T N E G TVF t FK T NRQS P NY R VIN ID FRD P E 322
Cdd:COG1505 235 DGRY L L I S RAL G - FYR N E L YLL DL PDG -------- EL V P L DLP F DAD Y SG V V N G G WLY - LL T RLDA P RG R LVA ID LAA P G 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 323 ESK W KVLV PE h EKD VLE WIACVR s NF LVL C YL H DV KNILQLH DL T t G A L LKTF PL - DV GS IV G Y SG QKKDT E I FY Q FTSF 401
Cdd:COG1505 305 PRN W TEFI PE - AEA VLE GVSWTG - GR LVL S YL D DV VSRVRVY DL D - G K L VREV PL p GL GS VS G F SG DDDGD E L FY S FTSF 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 402 L S P GII Y HC DL TKE E L E pr VFREVTVK g I DASDY QTV Q I F YP SKDGT KI P M FIVHKKG I KLDG SH P AF LYGYGGFNIS I T 481
Cdd:COG1505 382 L T P PTL Y RY DL GTG E S E -- LLKKPPAP - F DASDY EVE Q V F AT SKDGT RV P Y FIVHKKG L KLDG PN P TL LYGYGGFNIS L T 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 482 P N YS V S R L IFVR h M GG IL AVAN I RGGGEYG ET WH KG G ILA NKQN C FDDF QC AAE Y LI KE GYTSP K RL T I N GGSNGGLLV A 561
Cdd:COG1505 459 P S YS A S G L AWLE - R GG VY AVAN L RGGGEYG PA WH QA G LKE NKQN V FDDF IA AAE D LI AR GYTSP E RL A I Q GGSNGGLLV G 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 562 A CAN QRP D LFG C V IAQ V GVM DML KF HK Y T I G HA W TTD YG CS D SKQH F EW L VK YSP L HNVK lpea DDIQ YP SM L LL TADHD 641
Cdd:COG1505 538 A ALT QRP E LFG A V VCA V PLL DML RY HK F T A G AS W IAE YG DP D DPEE F AY L YA YSP Y HNVK ---- AGVA YP AT L FT TADHD 613
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41349456 642 DRV V P L H SL KF I A T LQ yivg RSRKQS NP L L IHVD T KA GHGAG K PT AKVI EE VS D MF AF IA R C L 704
Cdd:COG1505 614 DRV H P A H AR KF A A R LQ ---- AAQAGD NP V L YREE T EG GHGAG A PT SQRA EE AA D IY AF LW R N L 672
Name
Accession
Description
Interval
E-value
PreP
COG1505 Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
4-704
0e+00
Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
Pssm-ID: 441114 [Multi-domain]
Cd Length: 673
Bit Score: 860.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 4 L Q YP DVY RD ETA vqdy HGHKIC DPY A WLED P DS EQ T K A F V E AQN KI T VPF L EQC P I R GLYKE R MT EL YD Y PKYSCH FK K G 83
Cdd:COG1505 4 L T YP ATR RD DVV ---- DTTAVA DPY R WLED D DS PE T L A W V K AQN AV T RAY L AAI P R R EALRA R LL EL LN Y DRIPAP FK R G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 84 K RY FY F Y N T GLQNQ R VL Y V Q D S L EG E AR V F LDPN I LS D DGT VA L RGYAF S E DG EYF AY G LS AS GSD WVTIKFMK V DGAKE 163
Cdd:COG1505 80 G RY YN F W N D GLQNQ G VL R V R D G L DP E WE V L LDPN A LS E DGT WV L GAWSL S P DG RRL AY S LS EG GSD ARVVRVFD V ATGEF 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 164 LP D VL E RV K F S CM AW T h DG K G MF Y NS Y P qqdg KSD G TE T STNLHQ K L YYH VL GT D QSED I L CA E F P - D E P KWMG G AEL S D 242
Cdd:COG1505 160 VE D GF E WE K K S GV AW L - DG T G FV Y SR Y G ---- EPE G SL T DSGYPR K V YYH RR GT P QSED E L VF E G P p D D P ERYV G VSV S E 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 243 DGRY V L L S IRE G c DPV N R L WYC DL QQE ssgiagil KW V K L IDN F EGE Y DY V T N E G TVF t FK T NRQS P NY R VIN ID FRD P E 322
Cdd:COG1505 235 DGRY L L I S RAL G - FYR N E L YLL DL PDG -------- EL V P L DLP F DAD Y SG V V N G G WLY - LL T RLDA P RG R LVA ID LAA P G 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 323 ESK W KVLV PE h EKD VLE WIACVR s NF LVL C YL H DV KNILQLH DL T t G A L LKTF PL - DV GS IV G Y SG QKKDT E I FY Q FTSF 401
Cdd:COG1505 305 PRN W TEFI PE - AEA VLE GVSWTG - GR LVL S YL D DV VSRVRVY DL D - G K L VREV PL p GL GS VS G F SG DDDGD E L FY S FTSF 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 402 L S P GII Y HC DL TKE E L E pr VFREVTVK g I DASDY QTV Q I F YP SKDGT KI P M FIVHKKG I KLDG SH P AF LYGYGGFNIS I T 481
Cdd:COG1505 382 L T P PTL Y RY DL GTG E S E -- LLKKPPAP - F DASDY EVE Q V F AT SKDGT RV P Y FIVHKKG L KLDG PN P TL LYGYGGFNIS L T 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 482 P N YS V S R L IFVR h M GG IL AVAN I RGGGEYG ET WH KG G ILA NKQN C FDDF QC AAE Y LI KE GYTSP K RL T I N GGSNGGLLV A 561
Cdd:COG1505 459 P S YS A S G L AWLE - R GG VY AVAN L RGGGEYG PA WH QA G LKE NKQN V FDDF IA AAE D LI AR GYTSP E RL A I Q GGSNGGLLV G 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 562 A CAN QRP D LFG C V IAQ V GVM DML KF HK Y T I G HA W TTD YG CS D SKQH F EW L VK YSP L HNVK lpea DDIQ YP SM L LL TADHD 641
Cdd:COG1505 538 A ALT QRP E LFG A V VCA V PLL DML RY HK F T A G AS W IAE YG DP D DPEE F AY L YA YSP Y HNVK ---- AGVA YP AT L FT TADHD 613
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41349456 642 DRV V P L H SL KF I A T LQ yivg RSRKQS NP L L IHVD T KA GHGAG K PT AKVI EE VS D MF AF IA R C L 704
Cdd:COG1505 614 DRV H P A H AR KF A A R LQ ---- AAQAGD NP V L YREE T EG GHGAG A PT SQRA EE AA D IY AF LW R N L 672
Peptidase_S9_N
pfam02897 Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded ...
7-423
0e+00
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded beta-propeller domain protects the catalytic triad of prolyl oligopeptidase (see pfam00326), excluding larger peptides and proteins from proteolysis in the cytosol.
Pssm-ID: 397164 [Multi-domain]
Cd Length: 414
Bit Score: 522.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 7 P DVY RDE T AV QD YHG HKIC DPY A WLED P DS EQ T K A F VEA Q NK I T VP FL E Q C P - I R GLY KE RM T E L YD Y PKY S CH F K KG KR 85
Cdd:pfam02897 1 P PTA RDE H AV DE YHG DVVS DPY R WLED D DS PE T E A W VEA E NK Y T ED FL A Q L P r L R EKI KE EL T A L IN Y DDI S AP F R KG GY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 86 Y F YF Y N T G LQ NQ R VLY V QD S L E GE --- AR VFLDPN I LS D DGT - V AL R G Y AFS E DG EYF AY G LS A SGSDW V TI K F MK V DGA 161
Cdd:pfam02897 81 Y Y YF R N D G GK NQ S VLY R QD A L P GE gkp EE VFLDPN T LS E DGT f T AL G G F AFS P DG RLL AY S LS L SGSDW Y TI R F RD V ETG 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 162 KE LPDVLE R VKFS CMA W TH DGKG M FY NS Y PQQ D GK SD gte T S TNL H QK LYY H V LGT D QS E D I L CA EFP DE P K W MG GAE L S 241
Cdd:pfam02897 161 ED LPDVLE G VKFS GIV W AP DGKG F FY TR Y DKP D ER SD --- T G TNL N QK VWR H R LGT P QS Q D V L VF EFP KD P L W SL GAE R S 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 242 D DG R Y VLL S IRE G C D p V N R L W Y C DL QQ E SS giagil KWV KL I D N - F E GEYD YVT NEG TV F T F K TN RQS PN Y R VINI D FR D 320
Cdd:pfam02897 238 E DG K Y LFI S SAS G T D - T N E L Y Y L DL TK E TG ------ DTL KL V D G r F D GEYD VEH NEG DR F Y F L TN DGA PN F R LVRV D LN D 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 321 P EE S K WK V LVPE H E KD VLE w IAC V RS N F LVL C Y LH D VKNI LQ LH DL T TG A - L LKT FPL - D VGS IV G Y SG QKK D T E IF Y Q F 398
Cdd:pfam02897 311 P SP S E WK D LVPE R E DV VLE - EIT V FG N Y LVL S Y RR D ALSR LQ VF DL K TG K v L SRE FPL p G VGS VS G F SG EYD D S E LR Y S F 389
410 420
....*....|....*....|....*
gi 41349456 399 T SFL S PG I IY HC DL TKE ELE PRV FR 423
Cdd:pfam02897 390 S SFL T PG T IY DL DL ATG ELE LLK FR 414
PRK10115
PRK10115 protease 2; Provisional
20-700
8.81e-53
protease 2; Provisional
Pssm-ID: 182247 [Multi-domain]
Cd Length: 686
Bit Score: 193.95
E-value: 8.81e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 20 HG HKIC D P Y A WL E D PDSE Q TKA -- FVEAQ N KI -- T V PFLE Q CPIRGLY KE RMTELYDYPKYSCHF K K G K RY FYF Y NT G lq 95
Cdd:PRK10115 15 HG DTRI D N Y Y WL R D DTRS Q PEV ld YLHQE N SY gh R V MASQ Q ALQDRIL KE IIDRIPQREVSAPYI K N G Y RY RHI Y EP G -- 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 96 NQRVL Y VQD S LEG E A ---- RVF LD P N ILSDDGTV - A L R G Y A FSE D GEYF A YGLSASGSDWVT I K F MKVDGAKEL P DV L ER 170
Cdd:PRK10115 93 CEYAI Y QRQ S AFS E E wdew ETL LD A N KRAAHSEF y T L G G M A ITP D NTIM A LAEDFLSRRQYG I R F RNLETGNWY P EL L DN 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 171 V K f SCMA W TH D GKGMF Y NS ypqqdgksdg TETS T N L HQKLYY H VL GT DQ S E D I L CA E FP D EPKWMGGAELSDD g R YV LLS 250
Cdd:PRK10115 173 V E - PSFV W AN D SWTFY Y VR ---------- KHPV T L L PYQVWR H TI GT PA S Q D E L VY E EK D DTFYVSLHKTTSK - H YV VIH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 251 IREGCDPVNR L WYCD L QQ essgi A GILKWVKLIDNF E GEY D YVTNE gtv F TFKT NR QSP N YRVINIDF RD pe E SK W KV L V 330
Cdd:PRK10115 241 LASATTSEVL L LDAE L AD ----- A EPFVFLPRRKDH E YSL D HYQHR --- F YLRS NR HGK N FGLYRTRV RD -- E QQ W EE L I 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 331 P EH E KDV LE WIACVRSNFL V LCYLHDVKNIL Q LHDL T TGALLKT F -- P LD V g SIVG Y SGQKKDTEIF Y QFT S FLS P GIIY 408
Cdd:PRK10115 311 P PR E NIM LE GFTLFTDWLV V EERQRGLTSLR Q INRK T REVIGIA F dd P AY V - TWIA Y NPEPETSRLR Y GYS S MTT P DTLF 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 409 HC D L tk EEL E P RV FREVT V K G I DA SD Y QTVQIFYPSK DG TKI P MFI V HKKGIKLD G SH P AFL YGYG GFNI SI TPNY S V SR 488
Cdd:PRK10115 390 EL D M -- DTG E R RV LKQTE V P G F DA AN Y RSEHLWITAR DG VEV P VSL V YHRKHFRK G HN P LLV YGYG SYGA SI DADF S F SR 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 489 L IFVRH m G GIL A VANI RGGGE Y G ET W HKG G ILAN K Q N C F D D FQC A AEY L I K E GY T SP KRLTIN GGS N GG L L VAACA NQRP 568
Cdd:PRK10115 468 L SLLDR - G FVY A IVHV RGGGE L G QQ W YED G KFLK K K N T F N D YLD A CDA L L K L GY G SP SLCYGM GGS A GG M L MGVAI NQRP 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 569 D LF GC VIAQV GVM D MLKFH ----- KY T I G H aw TTDY G CSDSK Q HF E WLVK YSP LH NV klp E A DD iq YP SM L LL T AD HD DR 643
Cdd:PRK10115 547 E LF HG VIAQV PFV D VVTTM ldesi PL T T G E -- FEEW G NPQDP Q YY E YMKS YSP YD NV --- T A QA -- YP HL L VT T GL HD SQ 619
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 41349456 644 V VPLHSL K FI A T L QYI vgrs RKQSNP LL IHV D TKA GHG AGKPTA K VI E E V SDMF AF I 700
Cdd:PRK10115 620 V QYWEPA K WV A K L REL ---- KTDDHL LL LCT D MDS GHG GKSGRF K SY E G V AMEY AF L 672
Name
Accession
Description
Interval
E-value
PreP
COG1505 Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
4-704
0e+00
Prolyl endopeptidase PreP, S9A serine peptidase family [Amino acid transport and metabolism];
Pssm-ID: 441114 [Multi-domain]
Cd Length: 673
Bit Score: 860.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 4 L Q YP DVY RD ETA vqdy HGHKIC DPY A WLED P DS EQ T K A F V E AQN KI T VPF L EQC P I R GLYKE R MT EL YD Y PKYSCH FK K G 83
Cdd:COG1505 4 L T YP ATR RD DVV ---- DTTAVA DPY R WLED D DS PE T L A W V K AQN AV T RAY L AAI P R R EALRA R LL EL LN Y DRIPAP FK R G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 84 K RY FY F Y N T GLQNQ R VL Y V Q D S L EG E AR V F LDPN I LS D DGT VA L RGYAF S E DG EYF AY G LS AS GSD WVTIKFMK V DGAKE 163
Cdd:COG1505 80 G RY YN F W N D GLQNQ G VL R V R D G L DP E WE V L LDPN A LS E DGT WV L GAWSL S P DG RRL AY S LS EG GSD ARVVRVFD V ATGEF 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 164 LP D VL E RV K F S CM AW T h DG K G MF Y NS Y P qqdg KSD G TE T STNLHQ K L YYH VL GT D QSED I L CA E F P - D E P KWMG G AEL S D 242
Cdd:COG1505 160 VE D GF E WE K K S GV AW L - DG T G FV Y SR Y G ---- EPE G SL T DSGYPR K V YYH RR GT P QSED E L VF E G P p D D P ERYV G VSV S E 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 243 DGRY V L L S IRE G c DPV N R L WYC DL QQE ssgiagil KW V K L IDN F EGE Y DY V T N E G TVF t FK T NRQS P NY R VIN ID FRD P E 322
Cdd:COG1505 235 DGRY L L I S RAL G - FYR N E L YLL DL PDG -------- EL V P L DLP F DAD Y SG V V N G G WLY - LL T RLDA P RG R LVA ID LAA P G 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 323 ESK W KVLV PE h EKD VLE WIACVR s NF LVL C YL H DV KNILQLH DL T t G A L LKTF PL - DV GS IV G Y SG QKKDT E I FY Q FTSF 401
Cdd:COG1505 305 PRN W TEFI PE - AEA VLE GVSWTG - GR LVL S YL D DV VSRVRVY DL D - G K L VREV PL p GL GS VS G F SG DDDGD E L FY S FTSF 381
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 402 L S P GII Y HC DL TKE E L E pr VFREVTVK g I DASDY QTV Q I F YP SKDGT KI P M FIVHKKG I KLDG SH P AF LYGYGGFNIS I T 481
Cdd:COG1505 382 L T P PTL Y RY DL GTG E S E -- LLKKPPAP - F DASDY EVE Q V F AT SKDGT RV P Y FIVHKKG L KLDG PN P TL LYGYGGFNIS L T 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 482 P N YS V S R L IFVR h M GG IL AVAN I RGGGEYG ET WH KG G ILA NKQN C FDDF QC AAE Y LI KE GYTSP K RL T I N GGSNGGLLV A 561
Cdd:COG1505 459 P S YS A S G L AWLE - R GG VY AVAN L RGGGEYG PA WH QA G LKE NKQN V FDDF IA AAE D LI AR GYTSP E RL A I Q GGSNGGLLV G 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 562 A CAN QRP D LFG C V IAQ V GVM DML KF HK Y T I G HA W TTD YG CS D SKQH F EW L VK YSP L HNVK lpea DDIQ YP SM L LL TADHD 641
Cdd:COG1505 538 A ALT QRP E LFG A V VCA V PLL DML RY HK F T A G AS W IAE YG DP D DPEE F AY L YA YSP Y HNVK ---- AGVA YP AT L FT TADHD 613
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41349456 642 DRV V P L H SL KF I A T LQ yivg RSRKQS NP L L IHVD T KA GHGAG K PT AKVI EE VS D MF AF IA R C L 704
Cdd:COG1505 614 DRV H P A H AR KF A A R LQ ---- AAQAGD NP V L YREE T EG GHGAG A PT SQRA EE AA D IY AF LW R N L 672
Peptidase_S9_N
pfam02897 Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded ...
7-423
0e+00
Prolyl oligopeptidase, N-terminal beta-propeller domain; This unusual 7-stranded beta-propeller domain protects the catalytic triad of prolyl oligopeptidase (see pfam00326), excluding larger peptides and proteins from proteolysis in the cytosol.
Pssm-ID: 397164 [Multi-domain]
Cd Length: 414
Bit Score: 522.64
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 7 P DVY RDE T AV QD YHG HKIC DPY A WLED P DS EQ T K A F VEA Q NK I T VP FL E Q C P - I R GLY KE RM T E L YD Y PKY S CH F K KG KR 85
Cdd:pfam02897 1 P PTA RDE H AV DE YHG DVVS DPY R WLED D DS PE T E A W VEA E NK Y T ED FL A Q L P r L R EKI KE EL T A L IN Y DDI S AP F R KG GY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 86 Y F YF Y N T G LQ NQ R VLY V QD S L E GE --- AR VFLDPN I LS D DGT - V AL R G Y AFS E DG EYF AY G LS A SGSDW V TI K F MK V DGA 161
Cdd:pfam02897 81 Y Y YF R N D G GK NQ S VLY R QD A L P GE gkp EE VFLDPN T LS E DGT f T AL G G F AFS P DG RLL AY S LS L SGSDW Y TI R F RD V ETG 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 162 KE LPDVLE R VKFS CMA W TH DGKG M FY NS Y PQQ D GK SD gte T S TNL H QK LYY H V LGT D QS E D I L CA EFP DE P K W MG GAE L S 241
Cdd:pfam02897 161 ED LPDVLE G VKFS GIV W AP DGKG F FY TR Y DKP D ER SD --- T G TNL N QK VWR H R LGT P QS Q D V L VF EFP KD P L W SL GAE R S 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 242 D DG R Y VLL S IRE G C D p V N R L W Y C DL QQ E SS giagil KWV KL I D N - F E GEYD YVT NEG TV F T F K TN RQS PN Y R VINI D FR D 320
Cdd:pfam02897 238 E DG K Y LFI S SAS G T D - T N E L Y Y L DL TK E TG ------ DTL KL V D G r F D GEYD VEH NEG DR F Y F L TN DGA PN F R LVRV D LN D 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 321 P EE S K WK V LVPE H E KD VLE w IAC V RS N F LVL C Y LH D VKNI LQ LH DL T TG A - L LKT FPL - D VGS IV G Y SG QKK D T E IF Y Q F 398
Cdd:pfam02897 311 P SP S E WK D LVPE R E DV VLE - EIT V FG N Y LVL S Y RR D ALSR LQ VF DL K TG K v L SRE FPL p G VGS VS G F SG EYD D S E LR Y S F 389
410 420
....*....|....*....|....*
gi 41349456 399 T SFL S PG I IY HC DL TKE ELE PRV FR 423
Cdd:pfam02897 390 S SFL T PG T IY DL DL ATG ELE LLK FR 414
PtrB
COG1770 Protease II [Amino acid transport and metabolism];
19-706
1.14e-109
Protease II [Amino acid transport and metabolism];
Pssm-ID: 441376 [Multi-domain]
Cd Length: 686
Bit Score: 347.45
E-value: 1.14e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 19 Y HG HKIC D P YAWL E D PDSEQTK A FV EA Q N ------- KI T V P FL E Q cpirg L YK E --- R MT E ly D --- Y P kysch FKK G k R 85
Cdd:COG1770 23 H HG DTRV D D YAWL R D REDPEVL A YL EA E N ayteavm AP T K P LQ E T ----- L FA E mkg R IK E -- D dss V P ----- YRD G - G 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 86 Y F Y F -- YNT G L Q n QRVLYVQDSLEGEAR V F LD P N I L SDDGT - VA L R G YAF S E DG EYF AY GLSAS GS DWV T IKFMKVDGAK 162
Cdd:COG1770 90 Y W Y Y sr TEE G K Q - YPIYCRKPASGAGEE V L LD G N A L AEGHD f FS L G G LSV S P DG RLL AY SVDTV GS ERY T LRIKDLETGE 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 163 E LPDV L E RVKFS c MA W TH D GKGM FY nsypqqdgksd GTETS T NLHQKLYY H V LGTD QS ED I L CA E FP DE PKWM g G AELSD 242
Cdd:COG1770 169 D LPDV I E NTSGG - LV W AA D NRTL FY ----------- TRVDE T LRPYQVWR H R LGTD PA ED V L VY E EK DE RFFV - G VGKTR 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 243 D GRY VLLSI re G CDPVNRLWYC D LQQESS giagil KWVKLIDNF EG - EY D y V TNE G TV F TFK TN RQS PN YRVINIDFRD P 321
Cdd:COG1770 236 S GRY IVIGS -- G STTTSEVRLL D ADDPTA ------ EPRLVAPRE EG v EY S - V EHA G DR F YIL TN DDA PN FKLVRAPVDA P 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 322 EESK W KV L V P e H EKD V - LE WIACVR s NF LV LCYLHDVKNILQLH DL TT G ALLK - T F PLDVGSIVGYSGQKK DT EIF - Y QF 398
Cdd:COG1770 307 SREN W QE L I P - H RPG V l LE GVDAFK - DH LV VSERENGLPRIRVR DL DD G EEHE i A F DEEAYTAGLGGNPEF DT DTL r Y SY 384
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 399 T S FLS P GII Y HC DL TKE E LEPRVFR EV t VK G I D AS DY QTVQIFYPSK DGTK I P MFI V HK K GI KLDGS H P AF LYGYG GFN I 478
Cdd:COG1770 385 S S LTT P SSV Y DY DL ATG E RTLLKQQ EV - PG G F D PA DY VSERLWATAR DGTK V P VSL V YR K DT KLDGS A P LL LYGYG SYG I 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 479 SI T P NY S V SRL IFV - R hm G GIL A V A N IRGGGE Y G ET W HKG G I L AN K Q N C F D DF QCA AE Y LI KE GYTSP K R LTIN GGS N GG 557
Cdd:COG1770 464 SI D P SF S T SRL SLL d R -- G FVY A I A H IRGGGE L G RR W YED G K L LK K K N T F T DF IAC AE H LI AQ GYTSP G R IVAM GGS A GG 541
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 558 LL VA A C AN QR P D LF GC VIAQV GVM D M L K fhky T I --- GHAW TT ---- DY G C - SDS K QHFEWLVK YSP LH NVK l PE A ddiq 629
Cdd:COG1770 542 LL MG A V AN MA P E LF AG VIAQV PFV D V L T ---- T M ldp SLPL TT gewd EW G N p LND K EAYDYMKS YSP YD NVK - AQ A ---- 612
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 630 YP SM L LL T ADH D D RV V --- P lhs L K FI A T L qyivg R SR K QS - NPLL IHVDTK AGHG -- A G KPT A kv IE EV SDMF AF IARC 703
Cdd:COG1770 613 YP AI L VT T GLN D S RV Q ywe P --- A K WV A K L ----- R EL K TD d NPLL LKTNMD AGHG ga S G RFD A -- LK EV ALEY AF LLDL 682
...
gi 41349456 704 L NV 706
Cdd:COG1770 683 L GI 685
Peptidase_S9
pfam00326 Prolyl oligopeptidase family;
482-707
1.94e-71
Prolyl oligopeptidase family;
Pssm-ID: 459761 [Multi-domain]
Cd Length: 213
Bit Score: 231.35
E-value: 1.94e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 482 P NY S v SRLIFVRHM G GIL A V AN I RG G G E YGE TW H KG G ILANK QN C FDDF QC AAEYLI KE GYT S P K RL T I N GGS N GG L L VA 561
Cdd:pfam00326 1 P SF S - WNAQLLADR G YVV A I AN G RG S G G YGE AF H DA G KGDLG QN E FDDF IA AAEYLI EQ GYT D P D RL A I W GGS Y GG Y L TG 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 562 A CA NQRPDLF GCVI A Q V G V M D M L KFHKY T IGH -- AWTTDY G CS - D SKQHFEW L VK YSP LH NVK lpeaddi Q YP SM LL LTA 638
Cdd:pfam00326 80 A AL NQRPDLF KAAV A H V P V V D W L AYMSD T SLP ft ERYMEW G NP w D NEEGYDY L SP YSP AD NVK ------- V YP PL LL IHG 152
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 41349456 639 DH DDRV V P LH SLK FI A T LQ Y ivgrsrk QSN P L L IHVDTKA GHG A GKP TA K v I EE VSDMF AF IARC L NVD 707
Cdd:pfam00326 153 LL DDRV P P WQ SLK LV A A LQ R ------- KGV P F L LLIFPDE GHG I GKP RN K - V EE YAREL AF LLEY L GGT 213
PRK10115
PRK10115 protease 2; Provisional
20-700
8.81e-53
protease 2; Provisional
Pssm-ID: 182247 [Multi-domain]
Cd Length: 686
Bit Score: 193.95
E-value: 8.81e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 20 HG HKIC D P Y A WL E D PDSE Q TKA -- FVEAQ N KI -- T V PFLE Q CPIRGLY KE RMTELYDYPKYSCHF K K G K RY FYF Y NT G lq 95
Cdd:PRK10115 15 HG DTRI D N Y Y WL R D DTRS Q PEV ld YLHQE N SY gh R V MASQ Q ALQDRIL KE IIDRIPQREVSAPYI K N G Y RY RHI Y EP G -- 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 96 NQRVL Y VQD S LEG E A ---- RVF LD P N ILSDDGTV - A L R G Y A FSE D GEYF A YGLSASGSDWVT I K F MKVDGAKEL P DV L ER 170
Cdd:PRK10115 93 CEYAI Y QRQ S AFS E E wdew ETL LD A N KRAAHSEF y T L G G M A ITP D NTIM A LAEDFLSRRQYG I R F RNLETGNWY P EL L DN 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 171 V K f SCMA W TH D GKGMF Y NS ypqqdgksdg TETS T N L HQKLYY H VL GT DQ S E D I L CA E FP D EPKWMGGAELSDD g R YV LLS 250
Cdd:PRK10115 173 V E - PSFV W AN D SWTFY Y VR ---------- KHPV T L L PYQVWR H TI GT PA S Q D E L VY E EK D DTFYVSLHKTTSK - H YV VIH 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 251 IREGCDPVNR L WYCD L QQ essgi A GILKWVKLIDNF E GEY D YVTNE gtv F TFKT NR QSP N YRVINIDF RD pe E SK W KV L V 330
Cdd:PRK10115 241 LASATTSEVL L LDAE L AD ----- A EPFVFLPRRKDH E YSL D HYQHR --- F YLRS NR HGK N FGLYRTRV RD -- E QQ W EE L I 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 331 P EH E KDV LE WIACVRSNFL V LCYLHDVKNIL Q LHDL T TGALLKT F -- P LD V g SIVG Y SGQKKDTEIF Y QFT S FLS P GIIY 408
Cdd:PRK10115 311 P PR E NIM LE GFTLFTDWLV V EERQRGLTSLR Q INRK T REVIGIA F dd P AY V - TWIA Y NPEPETSRLR Y GYS S MTT P DTLF 389
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 409 HC D L tk EEL E P RV FREVT V K G I DA SD Y QTVQIFYPSK DG TKI P MFI V HKKGIKLD G SH P AFL YGYG GFNI SI TPNY S V SR 488
Cdd:PRK10115 390 EL D M -- DTG E R RV LKQTE V P G F DA AN Y RSEHLWITAR DG VEV P VSL V YHRKHFRK G HN P LLV YGYG SYGA SI DADF S F SR 467
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 489 L IFVRH m G GIL A VANI RGGGE Y G ET W HKG G ILAN K Q N C F D D FQC A AEY L I K E GY T SP KRLTIN GGS N GG L L VAACA NQRP 568
Cdd:PRK10115 468 L SLLDR - G FVY A IVHV RGGGE L G QQ W YED G KFLK K K N T F N D YLD A CDA L L K L GY G SP SLCYGM GGS A GG M L MGVAI NQRP 546
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 569 D LF GC VIAQV GVM D MLKFH ----- KY T I G H aw TTDY G CSDSK Q HF E WLVK YSP LH NV klp E A DD iq YP SM L LL T AD HD DR 643
Cdd:PRK10115 547 E LF HG VIAQV PFV D VVTTM ldesi PL T T G E -- FEEW G NPQDP Q YY E YMKS YSP YD NV --- T A QA -- YP HL L VT T GL HD SQ 619
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 41349456 644 V VPLHSL K FI A T L QYI vgrs RKQSNP LL IHV D TKA GHG AGKPTA K VI E E V SDMF AF I 700
Cdd:PRK10115 620 V QYWEPA K WV A K L REL ---- KTDDHL LL LCT D MDS GHG GKSGRF K SY E G V AMEY AF L 672
DAP2
COG1506 Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
442-705
1.43e-23
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain]
Cd Length: 234
Bit Score: 100.09
E-value: 1.43e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 442 YP S K DGT KI P MFIVHKKG ikl DGSH P AFL Y GY GG FN i S ITPNYSVSRLIFVRH mg G ILAV A - NI RG G GE YGET W HKGGI l 520
Cdd:COG1506 2 FK S A DGT TL P GWLYLPAD --- GKKY P VVV Y VH GG PG - S RDDSFLPLAQALASR -- G YAVL A p DY RG Y GE SAGD W GGDEV - 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 521 ankqncf DD FQC A AE YL IKEG Y TS P K R LT I N G G S N GG LLVAAC A NQR PD L F GCVI A QV GV M D MLKFHKY T igh AWT T DYG 600
Cdd:COG1506 75 ------- DD VLA A ID YL AARP Y VD P D R IG I Y G H S Y GG YMALLA A ARH PD R F KAAV A LA GV S D LRSYYGT T --- REY T ERL 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 601 CSDSKQHF E WLVKY SPL HN vklpe AD DIQY P s M LL LTADH DDRV V P LHSLKFIAT L qyivgrs R K QSN P LLIH V DTKA GH 680
Cdd:COG1506 145 MGGPWEDP E AYAAR SPL AY ----- AD KLKT P - L LL IHGEA DDRV P P EQAERLYEA L ------- K K AGK P VELL V YPGE GH 211
250 260
....*....|....*....|....*
gi 41349456 681 G AGKPT A KVIE E vs DMFA F IA R C L N 705
Cdd:COG1506 212 G FSGAG A PDYL E -- RILD F LD R H L K 234
DLH
COG0412 Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
436-574
3.21e-04
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440181 [Multi-domain]
Cd Length: 226
Bit Score: 42.65
E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 436 Q T VQIFY P SK DG TKI P MFIVHKK G ikl D G SH P A -- F L YGYG G F N IS I T pny S V S R L i FVRH mg G ILAV A - NIR G G G EY G E 512
Cdd:COG0412 2 T T ETVTI P TP DG VTL P GYLARPA G --- G G PR P G vv V L HEIF G L N PH I R --- D V A R R - LAAA -- G YVVL A p DLY G R G GP G D 72
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 41349456 513 TWHKGGI L ANKQN --- CFD D FQC A AEY L IKEGYTSPK R LTIN G GSN GG L L VAAC A NQR PDL FGC V 574
Cdd:COG0412 73 DPDEARA L MGALD pel LAA D LRA A LDW L KAQPEVDAG R VGVV G FCF GG G L ALLA A ARG PDL AAA V 137
FrsA
COG1073 Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
440-652
3.88e-04
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain]
Cd Length: 253
Bit Score: 42.59
E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 440 IF Y PS KDGT K IPMFIVHKK GIKL D G ---------- SH PA FLY -- G Y GG f NIS itpnysv S R LIFVRHM --- G - GI LA VAN 503
Cdd:COG1073 1 IF P PS DKVN K EDVTFKSRD GIKL A G dlylpagask KY PA VVV ah G N GG - VKE ------- Q R ALYAQRL ael G f NV LA FDY 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41349456 504 i RG G GE YGETWHKG G ILANK qncfd D FQC A AE YL IKEGYTS P K R LTIN G G S N GG LLVAAC A NQR P D l FGC VI AQVGVMDM 583
Cdd:COG1073 73 - RG Y GE SEGEPREE G SPERR ----- D ARA A VD YL RTLPGVD P E R IGLL G I S L GG GYALNA A ATD P R - VKA VI LDSPFTSL 145
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 41349456 584 LKFHKYTIGH A WTTDYGCSDSKQHFEWL ---- VKYS PL HNVKL peadd I QY P s M L LLTADH D DR V VPLH S LKF 652
Cdd:COG1073 146 EDLAAQRAKE A RGAYLPGVPYLPNVRLA slln DEFD PL AKIEK ----- I SR P - L L FIHGEK D EA V PFYM S EDL 212
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
