|
Name |
Accession |
Description |
Interval |
E-value |
| Tryp_SPc |
cd00190 |
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens ... |
631-872 |
1.53e-85 |
|
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.
:
Pssm-ID: 238113 [Multi-domain] Cd Length: 232 Bit Score: 272.61 E-value: 1.53e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 631 IIGGKNSLRGGWPWQVSLRLKSshgdGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQ 710
Cdd:cd00190 1 IVGGSEAKIGSFPWQVSLQYTG----GRHFCGGSLISPRWVLTAAHCV--YSSAPSNYTVRLGSHDLSSNEGGGQVIKVK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 711 QIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPlWRERPQKTASNCYITGWGDT--GRAYSRTLQQAAIPL 788
Cdd:cd00190 75 KVIVHPNYNPSTYDNDIALLKLKRP----VTLSDNVRPICLP-SSGYNLPAGTTCTVSGWGRTseGGPLPDVLQEVNVPI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 789 LPKRFCEERY--KGRFTGRMLCAGNlhEHKRVDSCQGDSGGPLMCERPGEsWVVYGVTSWGYGCGVKDSPGVYTKVSAFV 866
Cdd:cd00190 150 VSNAECKRAYsyGGTITDNMLCAGG--LEGGKDACQGDSGGPLVCNDNGR-GVLVGIVSWGSGCARPNYPGVYTRVSSYL 226
|
....*.
gi 300244530 867 PWIKSV 872
Cdd:cd00190 227 DWIQKT 232
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
280-380 |
1.97e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
:
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 158.27 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC 359
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 360 PKSSWGEHNCGHKEDAGVSCT 380
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
500-599 |
4.57e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
:
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 157.12 E-value: 4.57e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|
gi 300244530 580 IKQDIGRHNCRHSEDAGVIC 599
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVC 100
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
387-486 |
1.19e-40 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
:
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 144.41 E-value: 1.19e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASA-NHFEESTGPIWLDDVSCSGKETRFLQC 465
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGsAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 466 SRRQWGRHDCSHREDVSIACY 486
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
170-270 |
2.16e-30 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
:
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 115.13 E-value: 2.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLC 249
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 250 EKDIWQGGVCPQKMAAAVTCS 270
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| KR |
smart00130 |
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
99-164 |
3.05e-18 |
|
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides.
:
Pssm-ID: 214527 Cd Length: 83 Bit Score: 80.13 E-value: 3.05e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 300244530 99 WVSVTDFGAPCLRWAEVPPFLERSPPASWAQLrGQRHNFCRSPDG-AGRPWCFYGDARgkVDWGYCD 164
Cdd:smart00130 14 TVSVTKSGKPCQRWDSQTPHLHRFTPESFPDL-GLEENYCRNPDGdSEGPWCYTTDPN--VRWEYCD 77
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Tryp_SPc |
cd00190 |
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens ... |
631-872 |
1.53e-85 |
|
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.
Pssm-ID: 238113 [Multi-domain] Cd Length: 232 Bit Score: 272.61 E-value: 1.53e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 631 IIGGKNSLRGGWPWQVSLRLKSshgdGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQ 710
Cdd:cd00190 1 IVGGSEAKIGSFPWQVSLQYTG----GRHFCGGSLISPRWVLTAAHCV--YSSAPSNYTVRLGSHDLSSNEGGGQVIKVK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 711 QIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPlWRERPQKTASNCYITGWGDT--GRAYSRTLQQAAIPL 788
Cdd:cd00190 75 KVIVHPNYNPSTYDNDIALLKLKRP----VTLSDNVRPICLP-SSGYNLPAGTTCTVSGWGRTseGGPLPDVLQEVNVPI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 789 LPKRFCEERY--KGRFTGRMLCAGNlhEHKRVDSCQGDSGGPLMCERPGEsWVVYGVTSWGYGCGVKDSPGVYTKVSAFV 866
Cdd:cd00190 150 VSNAECKRAYsyGGTITDNMLCAGG--LEGGKDACQGDSGGPLVCNDNGR-GVLVGIVSWGSGCARPNYPGVYTRVSSYL 226
|
....*.
gi 300244530 867 PWIKSV 872
Cdd:cd00190 227 DWIQKT 232
|
|
| Tryp_SPc |
smart00020 |
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens ... |
630-869 |
4.55e-83 |
|
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.
Pssm-ID: 214473 Cd Length: 229 Bit Score: 266.08 E-value: 4.55e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 630 RIIGGKNSLRGGWPWQVSLRLksshGDGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDyHTLVPEEFEEEIGV 709
Cdd:smart00020 1 RIVGGSEANIGSFPWQVSLQY----GGGRHFCGGSLISPRWVLTAAHCV--RGSDPSNIRVRLGS-HDLSSGEEGQVIKV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 710 QQIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPlWRERPQKTASNCYITGWGDT---GRAYSRTLQQAAI 786
Cdd:smart00020 74 SKVIIHPNYNPSTYDNDIALLKLKEP----VTLSDNVRPICLP-SSNYNVPAGTTCTVSGWGRTsegAGSLPDTLQEVNV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 787 PLLPKRFCEERYKGRF--TGRMLCAGNLHEHKrvDSCQGDSGGPLMCErpGESWVVYGVTSWGYGCGVKDSPGVYTKVSA 864
Cdd:smart00020 149 PIVSNATCRRAYSGGGaiTDNMLCAGGLEGGK--DACQGDSGGPLVCN--DGRWVLVGIVSWGSGCARPGKPGVYTRVSS 224
|
....*
gi 300244530 865 FVPWI 869
Cdd:smart00020 225 YLDWI 229
|
|
| Trypsin |
pfam00089 |
Trypsin; |
631-869 |
9.85e-65 |
|
Trypsin;
Pssm-ID: 459667 [Multi-domain] Cd Length: 219 Bit Score: 216.15 E-value: 9.85e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 631 IIGGKNSLRGGWPWQVSLRLKSshgdGRLLCGATLLSSCWVLTAAHCFKrygnSTRSYAVRVGDYHTLVPEEFEEEIGVQ 710
Cdd:pfam00089 1 IVGGDEAQPGSFPWQVSLQLSS----GKHFCGGSLISENWVLTAAHCVS----GASDVKVVLGAHNIVLREGGEQKFDVE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 711 QIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPLWRERPQKTASnCYITGWGDTGRA-YSRTLQQAAIPLL 789
Cdd:pfam00089 73 KIIVHPNYNPDTLDNDIALLKLESP----VTLGDTVRPICLPDASSDLPVGTT-CTVSGWGNTKTLgPSDTLQEVTVPVV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 790 PKRFCEERYKGRFTGRMLCAGNlhehKRVDSCQGDSGGPLMCERPgeswVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWI 869
Cdd:pfam00089 148 SRETCRSAYGGTVTDTMICAGA----GGKDACQGDSGGPLVCSDG----ELIGIVSWGYGCASGNYPGVYTPVSSYLDWI 219
|
|
| COG5640 |
COG5640 |
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, ... |
630-873 |
1.48e-55 |
|
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444365 [Multi-domain] Cd Length: 262 Bit Score: 192.56 E-value: 1.48e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 630 RIIGGKNSLRGGWPWQVSLRlkSSHGDGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDyHTLVPEEfEEEIGV 709
Cdd:COG5640 30 AIVGGTPATVGEYPWMVALQ--SSNGPSGQFCGGTLIAPRWVLTAAHCV--DGDGPSDLRVVIGS-TDLSTSG-GTVVKV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 710 QQIVIHREYRPDRSDYDIALVRLQGPeeqcarfSSHVLPACLP--LWRERPQKTASncyITGWGDTGR---AYSRTLQQA 784
Cdd:COG5640 104 ARIVVHPDYDPATPGNDIALLKLATP-------VPGVAPAPLAtsADAAAPGTPAT---VAGWGRTSEgpgSQSGTLRKA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 785 AIPLLPKRFCEeRYKGRFTGRMLCAGNlhEHKRVDSCQGDSGGPLMCERPGEsWVVYGVTSWGYGCGVKDSPGVYTKVSA 864
Cdd:COG5640 174 DVPVVSDATCA-AYGGFDGGTMLCAGY--PEGGKDACQGDSGGPLVVKDGGG-WVLVGVVSWGGGPCAAGYPGVYTRVSA 249
|
....*....
gi 300244530 865 FVPWIKSVT 873
Cdd:COG5640 250 YRDWIKSTA 258
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
280-380 |
1.97e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 158.27 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC 359
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 360 PKSSWGEHNCGHKEDAGVSCT 380
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
500-599 |
4.57e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 157.12 E-value: 4.57e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|
gi 300244530 580 IKQDIGRHNCRHSEDAGVIC 599
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVC 100
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
387-486 |
1.19e-40 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 144.41 E-value: 1.19e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASA-NHFEESTGPIWLDDVSCSGKETRFLQC 465
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGsAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 466 SRRQWGRHDCSHREDVSIACY 486
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
285-380 |
2.27e-38 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 137.89 E-value: 2.27e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 285 GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAW-HQAYFGEG-SGPVMLDEVRCTGNELSIEQCPKS 362
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPsGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*...
gi 300244530 363 SWGEHNCGHKEDAGVSCT 380
Cdd:pfam00530 81 PWGNHNCSHSEDAGVICS 98
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
510-599 |
4.90e-35 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 128.26 E-value: 4.90e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 510 EGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARA-RTMAYFGEG-KGPIHVDNVKCTGNERSLADCIKQDIGRH 587
Cdd:pfam00530 6 EGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSApSGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHRPWGNH 85
|
90
....*....|..
gi 300244530 588 NCRHSEDAGVIC 599
Cdd:pfam00530 86 NCSHSEDAGVIC 97
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
392-485 |
8.44e-35 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 127.88 E-value: 8.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 392 GKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFEESTGPIWLDDVSCSGKETRFLQCSRR 468
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPsgcSYFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*..
gi 300244530 469 QWGRHDCSHREDVSIAC 485
Cdd:pfam00530 81 PWGNHNCSHSEDAGVIC 97
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
170-270 |
2.16e-30 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 115.13 E-value: 2.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLC 249
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 250 EKDIWQGGVCPQKMAAAVTCS 270
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
175-270 |
5.99e-26 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 102.45 E-value: 5.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 175 GKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTP--FSGLGLIPIYWSNVRCRGDEENILLCEKD 252
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*...
gi 300244530 253 IWQGGVCPQKMAAAVTCS 270
Cdd:pfam00530 81 PWGNHNCSHSEDAGVICS 98
|
|
| KR |
smart00130 |
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
99-164 |
3.05e-18 |
|
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides.
Pssm-ID: 214527 Cd Length: 83 Bit Score: 80.13 E-value: 3.05e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 300244530 99 WVSVTDFGAPCLRWAEVPPFLERSPPASWAQLrGQRHNFCRSPDG-AGRPWCFYGDARgkVDWGYCD 164
Cdd:smart00130 14 TVSVTKSGKPCQRWDSQTPHLHRFTPESFPDL-GLEENYCRNPDGdSEGPWCYTTDPN--VRWEYCD 77
|
|
| KR |
cd00108 |
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
100-164 |
7.14e-11 |
|
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides.
Pssm-ID: 238056 Cd Length: 83 Bit Score: 58.93 E-value: 7.14e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 300244530 100 VSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGqRHNFCRSPDGA-GRPWCFYGDarGKVDWGYCD 164
Cdd:cd00108 16 VSTTKSGKPCQRWNSQLPHQHKFNPERFPEGLL-EENYCRNPDGDpEGPWCYTTD--PNVRWEYCD 78
|
|
| Kringle |
pfam00051 |
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
100-164 |
1.42e-09 |
|
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta.
Pssm-ID: 395005 Cd Length: 79 Bit Score: 55.39 E-value: 1.42e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 300244530 100 VSVTDFGAPCLRWAEVPPFLERSPPAS---WAQLRGqrhNFCRSPDGAGRPWCFYGDarGKVDWGYCD 164
Cdd:pfam00051 13 VSTTESGRPCQAWDSQTPHRHSKYTPEnfpAKGLGE---NYCRNPDGDERPWCYTTD--PRVRWEYCD 75
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Tryp_SPc |
cd00190 |
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens ... |
631-872 |
1.53e-85 |
|
Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad residues.
Pssm-ID: 238113 [Multi-domain] Cd Length: 232 Bit Score: 272.61 E-value: 1.53e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 631 IIGGKNSLRGGWPWQVSLRLKSshgdGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQ 710
Cdd:cd00190 1 IVGGSEAKIGSFPWQVSLQYTG----GRHFCGGSLISPRWVLTAAHCV--YSSAPSNYTVRLGSHDLSSNEGGGQVIKVK 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 711 QIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPlWRERPQKTASNCYITGWGDT--GRAYSRTLQQAAIPL 788
Cdd:cd00190 75 KVIVHPNYNPSTYDNDIALLKLKRP----VTLSDNVRPICLP-SSGYNLPAGTTCTVSGWGRTseGGPLPDVLQEVNVPI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 789 LPKRFCEERY--KGRFTGRMLCAGNlhEHKRVDSCQGDSGGPLMCERPGEsWVVYGVTSWGYGCGVKDSPGVYTKVSAFV 866
Cdd:cd00190 150 VSNAECKRAYsyGGTITDNMLCAGG--LEGGKDACQGDSGGPLVCNDNGR-GVLVGIVSWGSGCARPNYPGVYTRVSSYL 226
|
....*.
gi 300244530 867 PWIKSV 872
Cdd:cd00190 227 DWIQKT 232
|
|
| Tryp_SPc |
smart00020 |
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens ... |
630-869 |
4.55e-83 |
|
Trypsin-like serine protease; Many of these are synthesised as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. A few, however, are active as single chain molecules, and others are inactive due to substitutions of the catalytic triad residues.
Pssm-ID: 214473 Cd Length: 229 Bit Score: 266.08 E-value: 4.55e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 630 RIIGGKNSLRGGWPWQVSLRLksshGDGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDyHTLVPEEFEEEIGV 709
Cdd:smart00020 1 RIVGGSEANIGSFPWQVSLQY----GGGRHFCGGSLISPRWVLTAAHCV--RGSDPSNIRVRLGS-HDLSSGEEGQVIKV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 710 QQIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPlWRERPQKTASNCYITGWGDT---GRAYSRTLQQAAI 786
Cdd:smart00020 74 SKVIIHPNYNPSTYDNDIALLKLKEP----VTLSDNVRPICLP-SSNYNVPAGTTCTVSGWGRTsegAGSLPDTLQEVNV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 787 PLLPKRFCEERYKGRF--TGRMLCAGNLHEHKrvDSCQGDSGGPLMCErpGESWVVYGVTSWGYGCGVKDSPGVYTKVSA 864
Cdd:smart00020 149 PIVSNATCRRAYSGGGaiTDNMLCAGGLEGGK--DACQGDSGGPLVCN--DGRWVLVGIVSWGSGCARPGKPGVYTRVSS 224
|
....*
gi 300244530 865 FVPWI 869
Cdd:smart00020 225 YLDWI 229
|
|
| Trypsin |
pfam00089 |
Trypsin; |
631-869 |
9.85e-65 |
|
Trypsin;
Pssm-ID: 459667 [Multi-domain] Cd Length: 219 Bit Score: 216.15 E-value: 9.85e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 631 IIGGKNSLRGGWPWQVSLRLKSshgdGRLLCGATLLSSCWVLTAAHCFKrygnSTRSYAVRVGDYHTLVPEEFEEEIGVQ 710
Cdd:pfam00089 1 IVGGDEAQPGSFPWQVSLQLSS----GKHFCGGSLISENWVLTAAHCVS----GASDVKVVLGAHNIVLREGGEQKFDVE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 711 QIVIHREYRPDRSDYDIALVRLQGPeeqcARFSSHVLPACLPLWRERPQKTASnCYITGWGDTGRA-YSRTLQQAAIPLL 789
Cdd:pfam00089 73 KIIVHPNYNPDTLDNDIALLKLESP----VTLGDTVRPICLPDASSDLPVGTT-CTVSGWGNTKTLgPSDTLQEVTVPVV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 790 PKRFCEERYKGRFTGRMLCAGNlhehKRVDSCQGDSGGPLMCERPgeswVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWI 869
Cdd:pfam00089 148 SRETCRSAYGGTVTDTMICAGA----GGKDACQGDSGGPLVCSDG----ELIGIVSWGYGCASGNYPGVYTPVSSYLDWI 219
|
|
| COG5640 |
COG5640 |
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, ... |
630-873 |
1.48e-55 |
|
Secreted trypsin-like serine protease [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444365 [Multi-domain] Cd Length: 262 Bit Score: 192.56 E-value: 1.48e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 630 RIIGGKNSLRGGWPWQVSLRlkSSHGDGRLLCGATLLSSCWVLTAAHCFkrYGNSTRSYAVRVGDyHTLVPEEfEEEIGV 709
Cdd:COG5640 30 AIVGGTPATVGEYPWMVALQ--SSNGPSGQFCGGTLIAPRWVLTAAHCV--DGDGPSDLRVVIGS-TDLSTSG-GTVVKV 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 710 QQIVIHREYRPDRSDYDIALVRLQGPeeqcarfSSHVLPACLP--LWRERPQKTASncyITGWGDTGR---AYSRTLQQA 784
Cdd:COG5640 104 ARIVVHPDYDPATPGNDIALLKLATP-------VPGVAPAPLAtsADAAAPGTPAT---VAGWGRTSEgpgSQSGTLRKA 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 785 AIPLLPKRFCEeRYKGRFTGRMLCAGNlhEHKRVDSCQGDSGGPLMCERPGEsWVVYGVTSWGYGCGVKDSPGVYTKVSA 864
Cdd:COG5640 174 DVPVVSDATCA-AYGGFDGGTMLCAGY--PEGGKDACQGDSGGPLVVKDGGG-WVLVGVVSWGGGPCAAGYPGVYTRVSA 249
|
....*....
gi 300244530 865 FVPWIKSVT 873
Cdd:COG5640 250 YRDWIKSTA 258
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
280-380 |
1.97e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 158.27 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 280 IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQC 359
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 360 PKSSWGEHNCGHKEDAGVSCT 380
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
500-599 |
4.57e-45 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 157.12 E-value: 4.57e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 500 VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|
gi 300244530 580 IKQDIGRHNCRHSEDAGVIC 599
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVC 100
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
387-486 |
1.19e-40 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 144.41 E-value: 1.19e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASA-NHFEESTGPIWLDDVSCSGKETRFLQC 465
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGsAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 466 SRRQWGRHDCSHREDVSIACY 486
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
285-380 |
2.27e-38 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 137.89 E-value: 2.27e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 285 GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAW-HQAYFGEG-SGPVMLDEVRCTGNELSIEQCPKS 362
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPsGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*...
gi 300244530 363 SWGEHNCGHKEDAGVSCT 380
Cdd:pfam00530 81 PWGNHNCSHSEDAGVICS 98
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
510-599 |
4.90e-35 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 128.26 E-value: 4.90e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 510 EGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARA-RTMAYFGEG-KGPIHVDNVKCTGNERSLADCIKQDIGRH 587
Cdd:pfam00530 6 EGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSApSGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHRPWGNH 85
|
90
....*....|..
gi 300244530 588 NCRHSEDAGVIC 599
Cdd:pfam00530 86 NCSHSEDAGVIC 97
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
392-485 |
8.44e-35 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 127.88 E-value: 8.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 392 GKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS---ANHFEESTGPIWLDDVSCSGKETRFLQCSRR 468
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPsgcSYFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*..
gi 300244530 469 QWGRHDCSHREDVSIAC 485
Cdd:pfam00530 81 PWGNHNCSHSEDAGVIC 97
|
|
| SR |
smart00202 |
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ... |
170-270 |
2.16e-30 |
|
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.
Pssm-ID: 214555 [Multi-domain] Cd Length: 101 Bit Score: 115.13 E-value: 2.16e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLC 249
Cdd:smart00202 1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80
|
90 100
....*....|....*....|.
gi 300244530 250 EKDIWQGGVCPQKMAAAVTCS 270
Cdd:smart00202 81 PHSGWGSHNCSHGEDAGVVCS 101
|
|
| SRCR |
pfam00530 |
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ... |
175-270 |
5.99e-26 |
|
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.
Pssm-ID: 459844 Cd Length: 98 Bit Score: 102.45 E-value: 5.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 175 GKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTP--FSGLGLIPIYWSNVRCRGDEENILLCEKD 252
Cdd:pfam00530 1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCsyFGPGSTGPIWLDDVRCSGNETSLWQCPHR 80
|
90
....*....|....*...
gi 300244530 253 IWQGGVCPQKMAAAVTCS 270
Cdd:pfam00530 81 PWGNHNCSHSEDAGVICS 98
|
|
| KR |
smart00130 |
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like ... |
99-164 |
3.05e-18 |
|
Kringle domain; Named after a Danish pastry. Found in several serine proteases and in ROR-like receptors. Can occur in up to 38 copies (in apolipoprotein(a)). Plasminogen-like kringles possess affinity for free lysine and lysine- containing peptides.
Pssm-ID: 214527 Cd Length: 83 Bit Score: 80.13 E-value: 3.05e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 300244530 99 WVSVTDFGAPCLRWAEVPPFLERSPPASWAQLrGQRHNFCRSPDG-AGRPWCFYGDARgkVDWGYCD 164
Cdd:smart00130 14 TVSVTKSGKPCQRWDSQTPHLHRFTPESFPDL-GLEENYCRNPDGdSEGPWCYTTDPN--VRWEYCD 77
|
|
| eMpr |
COG3591 |
V8-like Glu-specific endopeptidase [Posttranslational modification, protein turnover, ... |
655-849 |
5.82e-11 |
|
V8-like Glu-specific endopeptidase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442810 [Multi-domain] Cd Length: 194 Bit Score: 62.39 E-value: 5.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 655 GDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRSYAVRVG-DYHTLVPEEFeeeiGVQQIVIHREYRPD-RSDYDIALVRL 732
Cdd:COG3591 8 DGGGGVCTGTLIGPNLVLTAGHCVYDGAGGGWATNIVFVpGYNGGPYGTA----TATRFRVPPGWVASgDAGYDYALLRL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 300244530 733 QGPEEQCARFsshvlpacLPLWRERPQKTASNCYITGWGDtGRAYSRTLQQAaipllpkrfceerykGRFTGRmlcAGNL 812
Cdd:COG3591 84 DEPLGDTTGW--------LGLAFNDAPLAGEPVTIIGYPG-DRPKDLSLDCS---------------GRVTGV---QGNR 136
|
170 180 190
....*....|....*....|....*....|....*..
gi 300244530 813 HEHkRVDSCQGDSGGPLMCERPGeSWVVYGVTSWGYG 849
Cdd:COG3591 137 LSY-DCDTTGGSSGSPVLDDSDG-GGRVVGVHSAGGA 171
|
|
| KR |
cd00108 |
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as ... |
100-164 |
7.14e-11 |
|
Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and fibrinolytic proteins, some serine proteases and plasma proteins. Plasminogen-like kringles possess affinity for free lysine and lysine-containing peptides.
Pssm-ID: 238056 Cd Length: 83 Bit Score: 58.93 E-value: 7.14e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 300244530 100 VSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGqRHNFCRSPDGA-GRPWCFYGDarGKVDWGYCD 164
Cdd:cd00108 16 VSTTKSGKPCQRWNSQLPHQHKFNPERFPEGLL-EENYCRNPDGDpEGPWCYTTD--PNVRWEYCD 78
|
|
| Kringle |
pfam00051 |
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, ... |
100-164 |
1.42e-09 |
|
Kringle domain; Kringle domains have been found in plasminogen, hepatocyte growth factors, prothrombin, and apolipoprotein A. Structure is disulfide-rich, nearly all-beta.
Pssm-ID: 395005 Cd Length: 79 Bit Score: 55.39 E-value: 1.42e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 300244530 100 VSVTDFGAPCLRWAEVPPFLERSPPAS---WAQLRGqrhNFCRSPDGAGRPWCFYGDarGKVDWGYCD 164
Cdd:pfam00051 13 VSTTESGRPCQAWDSQTPHRHSKYTPEnfpAKGLGE---NYCRNPDGDERPWCYTTD--PRVRWEYCD 75
|
|
| SRCR_2 |
pfam15494 |
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ... |
400-432 |
5.63e-03 |
|
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.
Pssm-ID: 464747 Cd Length: 99 Bit Score: 37.31 E-value: 5.63e-03
10 20 30
....*....|....*....|....*....|....*
gi 300244530 400 LEVY--YRGQWGTVCDDGWTELNTYVVCRQLGFKY 432
Cdd:pfam15494 6 LQVYssARPSWLPVCSDDWNPAYGRAACQQLGYLR 40
|
|
| SRCR_2 |
pfam15494 |
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ... |
514-543 |
8.00e-03 |
|
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.
Pssm-ID: 464747 Cd Length: 99 Bit Score: 36.54 E-value: 8.00e-03
10 20 30
....*....|....*....|....*....|..
gi 300244530 514 EVFI--NGQWGTICDDGWTDKDAAVICRQLGY 543
Cdd:pfam15494 7 QVYSsaRPSWLPVCSDDWNPAYGRAACQQLGY 38
|
|
| |
